Subjects taking RAL by chewing had significantly higher drug exposure ( RAL area under the curve -LSB- AUC -RSB- ( @-@ ) : @ @ versus @ @ ng h/mL , P < @ ) and reduced pharmacokinetic variability compared with those taking the drug by swallowing the whole tablet , with no difference in the minimum RAL concentrations ( RAL C ( min ) : @ @ versus @ @ ng/mL , P = @ ) .