In the @ patients not receiving catecholamines at blood sampling , endogenous p-noradrenaline correlated positively with adrenaline , syndecan @ , soluble vascular endothelial growth factor receptor @ , soluble CD@ ligand , tissue-type plasminogen activator , and plasminogen activator inhibitor @ ( PAI-@ ) and negatively with PAI-@ / tissue-type plasminogen activator ratio ( all P < @ ) and was independently associated with syndecan @ , soluble vascular endothelial growth factor receptor @ , and PAI-@ ( all P < @ ) , and @ - and @-day mortality ( P < @ ) .