The least squares ( LS ) mean change ( @ % confidence interval ) from baseline in HbA@c at week @ was -@ % ( -@ to @ ) in the placebo group , compared with -@ % ( -@ to -@ ) in the tofogliflozin @ mg group , -@ % ( -@ to -@ ) in the tofogliflozin @ mg group , and -@ % ( -@ to -@ ) in the tofogliflozin @ mg group ( p < @ for the LS mean differences in all tofogliflozin groups vs placebo ) .