Of the patients who received placebo , there was a statistically significant improvement demonstrated in the O'Leary-Sant Interstitial Cystitis Symptom and Problem Indexes of -@ ( @ % confidence interval -LSB- CI -RSB- , @-@ @ ) , Interstitial Cystitis Symptom Index of -@ ( @ % CI , @-@ @ ) , Interstitial Cystitis Problem Index of -@ ( @ % CI , @-@ @ ) , and Pelvic Pain , Urgency , Frequency scale of -@ ( @ % CI , @-@ @ ) at week @ compared with baseline .