In both trials , the most common afatinib-related grade @-@ adverse events were rash or acne ( @ -LSB- @ % -RSB- of @ patients in LUX-Lung @ and @ -LSB- @ % -RSB- of @ patients in LUX-Lung @ ) , diarrhoea ( @ -LSB- @ % -RSB- and @ -LSB- @ % -RSB- ) , paronychia ( @ -LSB- @ % -RSB- in LUX-Lung @ only ) , and stomatitis or mucositis ( @ -LSB- @ % -RSB- in LUX-Lung @ only ) .