At @-year biopsy , baseline chronic inflammation was associated with lower mean tumor volume ( @ l vs. @ l ; P = @ ) , number of biopsy cores involved ( @ vs. @ ; P < @ ) , percent of cores involved ( @ % vs. @ % ; P < @ ) , core involvement ( @ l vs. @ l ; P < @ ) , and overall percent tumor involvement ( @ % vs. @ % ; P < @ ) .