Patients were randomly assigned @:@ to fulvestrant @ mg administered as two @-mL intramuscular injections on days @ , @ , and @ and every @ ( @ ) days thereafter or fulvestrant @ mg administered as two @-mL intramuscular injections ( one fulvestrant and one placebo -LSB- identical in appearance to study drug -RSB- ) on days @ , @ ( two placebo injections only ) , and @ and every @ ( @ ) days thereafter .