Blood samples were harvested on the morning of the @nd admission day ( TO ) , immediately after operation ( T@ ) , on the morning of the @rd day after operation ( T@ ) , and on the morning of the @th day after operation ( T@ ) to detect prothrombin time ( PT ) , thrombin time ( TT ) , activated partial thromboplastin time ( APTT ) , levels of FIB and D-dimer ( D-D ) , changes of white blood cell ( WBC ) , neutrophils ( N ) , C-reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) , and IL-@ .