@ patients had complete @-h BP readings ; compared with placebo , daglutril significantly reduced @-h systolic ( difference -@ mm Hg , SD @ ; p = @ ) , diastolic ( -@ , @ ; p = @ ) , pulse ( -@ , @ ; p = @ ) , and mean ( -@ , @ ; p = @ ) BP , as well as all night-time BP readings and daytime systolic , pulse , and mean BP , but not diastolic BP .