L-NMMA was associated with a significant decrease in RPF ( CON-LNMMA : -@ @ % -LSB- P = @ -RSB- ; CHF-LNMMA : -@ @ % -LSB- P = @ -RSB- ) and a profound increase in RVR in both CHF and CON ( CON-LNMMA : +@ @ % -LSB- P = @ -RSB- ; CHF-LNMMA : +@ @ % -LSB- P = @ -RSB- ) .