The adjusted annual rate of change in FVC was -@ ml with nintedanib versus -@ ml with placebo ( difference , @ ml ; @ % confidence interval -LSB- CI -RSB- , @ to @ ; P < @ ) in INPULSIS-@ and -@ ml with nintedanib versus -@ ml with placebo ( difference , @ ml ; @ % CI , @ to @ ; P < @ ) in INPULSIS-@ .