Although the subdose of @ IU is able to trigger equivalent kinetics of IL-@ / CXCL-@ and MCP-@ / CCL-@ , only the subdose of @,@ IU is able to trigger similar kinetics of MIG/CXCL -@ , pro-inflammatory ( TNF , IFN - and IL-@ ) and modulatory cytokines ( IL-@ and IL-@ ) .