There were amelioration of haemodinamic instability , especially in MARS-group ( increase in ADmean was @ % in MARS ( p = @ ) and @ % in Prometheus-group ( p = @ ) ) , increase in P/F ratio ( @ % in Prometheus-group ( p = @ ) ) , decrease in serum total bilirubin ( @ % in MARS-group ( p = @ ) and @ % in Prometheus-group ( p < @ ) ) and unconjugated bilirubin levels ( @ % in Prometheus-group ( p = @ ) ) , also we had decreasing in serum aminotransferase levels and trend to increasing in serum cholinesterase level ( @ % in MARS-group ( p = @ ) and @ % in Prometheus-group ( p = @ ) ) .