At @-months , there was a non-significant difference in change score for FACIT-Sp between intervention and control groups ( @ points -LSB- @ % CI -@ to @ -RSB- , p = @ ) , a significant difference in QUAL-E ( @ -LSB- @ to @ -RSB- , p = @ ) and FAMCARE-P@ ( @ -LSB- @ to @ -RSB- , p = @ ) , and no difference in ESAS ( -@ -LSB- -@ to @ -RSB- , p = @ ) or CARES-MIS ( -@ -LSB- -@ to @ -RSB- , p = @ ) .