During the @-year follow-up , patients with reduced LTPA at baseline had an increased risk of CV events ( adjusted hazard ratio @ -LSB- @ % CI @-@ @ ; P = @ -RSB- , @ -LSB- @-@ @ ; P = @ -RSB- , and @ -LSB- @-@ @ ; P = @ -RSB- for no LTPA , LTPA irregularly , and LTPA two to three times weekly , respectively ) compared with those with LTPA more than three times weekly .