In a multicenter randomized clinical trial , including @ hospitals and all @ HBOT centers in the Netherlands , we plan to enroll @ patients with Types @ or @ diabetes , a Wagner @ , @ or @ ulcer of the leg present for at least @ weeks , and concomitant leg ischemia , defined as an ankle systolic blood pressure of < @mmHg , a toe systolic blood pressure of < @mmHg or a forefoot transcutaneous oxygen tension ( TcpO@ ) of < @mmHg .