Among patients with baseline galectin-@ levels in the top quartile of the distribution , CRT-D was associated with a @ % reduction in risk of the primary end point ( hazard ratio -LSB- HR -RSB- @ , @ % confidence interval -LSB- CI -RSB- @-@ @ ) , whereas among patients with lower baseline galectin-@ values CRT-D was associated with a @ % decrease in risk ( HR @ , @ % CI .