At a median follow-up of @ years , biochemotherapy improved RFS ( hazard ratio -LSB- HR -RSB- , @ ; @ % CI , @ to @ ; P = @ ) , with a median RFS of @ years ( @ % CI , @ years to not reached -LSB- NR -RSB- ) versus @ years for HDI ( @ % CI , @ to @ years ) and a @-year RFS of @ % versus @ % .