The most common grade @-@ adverse events were skin rash ( @ -LSB- @ % -RSB- of @ patients vs @ -LSB- @ % -RSB- of @ patients ) , neutropenia ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , diarrhoea ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , and lethargy ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) .