After two years , a significant increase was found in the physical health composite score ( = +@ in group a , = +@ in group b , p < @ in both ) , mental health composite score ( = +@ in group a , = +@ in group b , p < @ in both ) , in eight MSQoL sub-items of group a and in seven sub-items in group b. Conversely , the untreated group showed a slight decrease in seven domains .