Methazolamide treatment was associated with a HbA@c of -@ % ( @ % CI -@ , @ ; P < @ ) ( -@ mmol/mol -LSB- -@ , @ -RSB- ) , an increase in the proportion of patients achieving HbA@c @ % ( @ mmol/mol ) from @ to @ % , a rapid reduction in alanine aminotransferase ( @ units/L ) , and weight loss ( @ % ) in metformin-cotreated patients .