Sixty-three mildly hypercholesterolemic adults who were preselected as possessing either high endogenous cholesterol synthesis -LSB- HS ; n = @ ; L : C = @ @ mol/mmol ( mean SD ) -RSB- or low endogenous cholesterol synthesis ( LS ; n = @ ; L : C = @ @ mol/mmol ) on the basis of baseline L : C consumed @ g PS/d or a placebo for @ d with the use of a dual-center , single-blind , randomized crossover design .