From weeks @ to @ , curcumin was significantly more effective than placebo in improving several mood-related symptoms , demonstrated by a significant group x time interaction for IDS-SR@ total score ( F@ , @ = @ , p = @ ) and IDS-SR@ mood score ( F@ , @ = @ , p = @ ) , and a non-significant trend for STAI trait score ( F@ , @ = @ , p = @ ) .