The decrease was significantly more pronounced in patients receiving osteopathy at day @ -LSB- -@ ( -@ to @ ) vs. @ ( -@ to @ ) , P = @ -RSB- , day @ -LSB- -@ ( -@ to @ ) vs. @ ( -@ to @ ) , P = @ -RSB- , and day @ -LSB- -@ ( -@ to -@ ) vs. @ ( -@ to @ ) , P = @ -RSB- with a concomitant increase in Qol ( P = @ at day @ , P = @ at day @ , P = @ at day @ ) .