Compared with before surgery , in the observation group , levels of IL-@ , IL-@ and IL-@ had no significant differences after operation ( P > @ ) , but TNF - level increased y ( p < @ ) , whereas in control group , IL-@ level had no significant difference ( p > @ ) , IL-@ level decreased obviously ( p < @ ) , IL-@ level increased markedly first and then decreased gradually as time passed but its level remained elevated ( p < @ ) , and TNF - level increased first and then decreased , and there was no significant difference @ d after operation ( p > @ ) .