During the normoglycemic-hyperinsulinemic clamp , flow-mediated dilatation ( FMD ) increased , while soluble intercellular adhesion molecule ( sICAM-@ ) , plasma @-iso-prostaglandin F@ ( @-iso-PGF@ ) , nitrotyrosine , and interleukin ( IL ) -@ decreased compared with normoglycemic-normoinsulinemic clamp .