At month @ , LGH increased clamp glucose infusion rates ( P < @ ) and IGF-@ to IGFBP-@ molar ratio ( P < @ ) , but fasting glucose , insulin , C-peptide , free fatty acid , adiponectin , IGF-@ bioactivity , IGF-@ , IGFBP-@ , @-hour CPRs , adipocyte size , adipocyte @-hydroxysteroid dehydrogenase activity , intrahepatic lipid , extramyocellular , or intramyocellular were unchanged .