At @-month median follow-up , superior efficacy of EC-Doc -LSB- versus FEC ( a combination of @-fluorouracil , epirubicin , and cyclophosphamide ) -RSB- was seen in EFS and OS : @-year EFS : @ % versus @ % ( P = @ ) ; @-year OS : @ % versus @ % ( P = @ ) ; both tests one-tailed .