Plasma was sampled at baseline , @ hours , and @ hours after randomization or transfusion , and concentrations of interleukin ( IL ) -@ , IL-@ , IL-@ , IL-@ , IL-@ , IL-@ , IL-@ , IL-@-p@ , interferon - , tumor necrosis factor - , human neutrophil elastase , soluble L-selectin , and C-reactive protein were measured using cytokine bead array analysis and an enzyme-linked immunosorbent assay .