During stair ascent and descent , lateral wedge insoles significantly ( P < @ ) reduced the @st peak external knee adduction moment in early stance ( ascent @ % , descent @ % ) , the trough in mid stance ( ascent @ % , descent @ % ) , @nd peak in the late stance ( ascent @ % , descent @ % ) and the knee adduction angular impulse compared to the control ( standard shoe ) with large effect sizes ( @-@ @ ) .