Participants with non-alcoholic fatty liver disease ( defined as ( @ ) H magnetic resonance spectroscopy liver-fat content > @ % ) , insulin resistance ( homoeostatic model assessment of insulin resistance -LSB- HOMA-IR -RSB- of at least @ mmol/LmU/L ) , BMI greater than @ kg/m ( @ ) , and aged @-@ years were randomly assigned by interactive voice response system in a @:@ ratio , stratified for triglyceride concentration ( < @ mmol/L or @ mmol/L ) , to oral RO@ ( @ mg twice daily ) or matching placebo for @ weeks .