In stage @ , we randomly allocated patients @:@ with the Pocock and Simon algorithm to intravenous rituximab ( @ mg/m ( @ ) ) or fixed-dose subcutaneous rituximab ( @ mg ) , stratified by induction chemotherapy regimen ( cyclophosphamide , doxorubicin , vincristine , prednisone or cyclophosphamide , vincristine , prednisone ) , Follicular Lymphoma International Prognostic Index score , and region .