Alectinib was well tolerated , with the most common adverse events being fatigue ( @ -LSB- @ % -RSB- ; all grade @-@ ) , myalgia ( eight -LSB- @ % -RSB- ; all grade @-@ ) , and peripheral oedema ( seven -LSB- @ % -RSB- grade @-@ , one -LSB- @ % -RSB- grade @ ) .