Double-dummy , double-blind study ( NCT@ ) ; @ adults with @ swollen joints , @ tender joints and C-reactive protein ( CRP ) @ mg/dL randomized @:@ to SC abatacept ( @ mg weekly ) with IV loading ( @ mg/kg on Day @ ) , or IV abatacept ( @ mg/kg monthly ) for @ days , both also receiving MTX ( @-@ mg/week ) .