In a double-blind controlled study , @ patients with an established diagnosis of CF and a documented nasal infection with Pseudomonas aeruginosa and/or Staphylococcus aureus -LSB- @ males ( @ % ) , median age of @ years ( range @-@ yrs ) -RSB- , were randomized to receive the nasal spray formulation containing hyaluronate and tobramycin ( N = @ ) or hyaluronate alone ( N = @ ) for @ days .