In the multivariate analysis , history of migraine ( hazard ratio -LSB- HR -RSB- , @ ; P = @ ) , narrower neuroretinal rim width at baseline ( HR , @ ; P = @ ) , use of systemic - blockers ( HR , @ ; P = @ ) , low mean systolic blood pressure ( HR , @ ; P = @ ) , and low mean arterial ocular perfusion pressure during follow-up ( HR , @ ; P = @ ) were significant and independent risk factors for disc hemorrhage detection .