In both studies , we noted improvements in trough FEV@ on day @ for both doses of UMEC plus VI compared with TIO monotherapy ( study @ , UMEC @ g plus VI @ g : @ L -LSB- @ % CI @ to @ ; p = @ -RSB- ; study @ , UMEC @ g plus VI @ g : @ L -LSB- @ to @ ; p = @ -RSB- ; study @ , UMEC @ g plus VI @ g : @ L -LSB- @ to @ ; p = @ -RSB- ; study @ , UMEC @ g plus VI @ g : @ L -LSB- @ to @ ; nominal p = @ -RSB- ) .