Tesamorelin significantly reduced visceral adipose tissue ( mean change , -@ cm@ -LSB- @ % CI , -@ to -@ cm@ -RSB- with tesamorelin vs @ cm@ -LSB- @ % CI , -@ to @ cm@ -RSB- with placebo ; treatment effect , -@ cm@ -LSB- @ % CI , -@ to -@ cm@ -RSB- ; P = @ ) and liver fat ( median change in lipid to water percentage , -@ % -LSB- interquartile range -LCB- IQR -RCB- , -@ % to @ % -RSB- with tesamorelin vs @ % -LSB- IQR , -@ % to @ % -RSB- with placebo ; P = @ ) over @ months , for a net treatment effect of -@ % in lipid to water percentage .