In exploratory analyses , intervention patients had fewer days of opioid administration ( median , @ -LSB- IQR , @-@ -RSB- days vs @ -LSB- IQR , @-@ -RSB- days ; P = @ ) , were exposed to fewer sedative classes ( median , @ -LSB- IQR , @-@ -RSB- classes vs @ -LSB- IQR , @-@ -RSB- classes ; P < @ ) , and were more often awake and calm while intubated ( median , @ % -LSB- IQR , @ % -@ % -RSB- of days vs @ % -LSB- IQR , @ % -@ % -RSB- of days ; P = @ ) than control patients , respectively ; however , intervention patients had more days with any report of a pain score @ ( median , @ % -LSB- IQR , @ % -@ % -RSB- of days vs @ % -LSB- IQR , @ % -@ % -RSB- of days ; P < @ ) and any report of agitation ( median , @ % -LSB- IQR , @ % -@ % -RSB- vs @ % -LSB- IQR , @ % -@ % -RSB- ; P = @ ) , respectively .