We examined associations of PIK@CA oncogene mutation with relapse , survival , and treatment efficacy in @ stage III colon carcinoma case subjects within a randomized adjuvant chemotherapy trial ( @-fluorouracil and leucovorin -LSB- FU/LV -RSB- vs irinotecan -LSB- CPT@ -RSB- , fluorouracil and leucovorin -LSB- IFL -RSB- ; Cancer and Leukemia Group B @ -LSB- Alliance -RSB- ) .