Regarding the two levels of the two examined factors for aconite cake-separated moxibustion , after the first course of treatment , the changes in HAMA scores were significantly different for the two tested moxibustion frequencies ( P = @ ) , with greater changes for the `` @ treatments/wk '' groups than for the `` @ treatments/wk '' groups ; in addition , there were interaction effects between the number of cones and moxibustion frequency ( P = @ ) .