Pioglitazone treatment resulted in a change in augmentation index of -@ % units ( @ % confidence interval -LSB- @ % CI -RSB- -@ , -@ ) ( P = @ ) and in diastolic blood pressure of -@ mm Hg ( @ % CI -@ , -@ ) ( P = @ ) , but did not significantly change aortic PWV ( P = @ ) or reactive hyperemia index ( P = @ ) .