Grade @ toxicities were reported at expected levels : @ ( @ % ) of @ patients who received treatment and had full treatment details had grade @ neutropenia , @ ( @ % ) had infection , @ ( @ % ) had fatigue , @ ( @ % ) had muscle and joint pains , @ ( @ % ) had nausea , @ ( @ % ) had vomiting , @ ( @ % ) had neuropathy , @ ( @ % ) had transaminitis , @ ( @ % ) had acute hypersensitivity , and @ ( @ % ) had a rash .