In analyses restricted to eyes with bilateral large drusen at baseline , the direct comparison of lutein/zeaxanthin vs beta carotene showed hazard ratios of @ ( @ % CI , @-@ @ ; P = @ ) for progression to late AMD , @ ( @ % CI , @-@ @ ; P = @ ) for neovascular AMD , and @ ( @ % CI , @-@ @ ; P = @ ) for central geographic atrophy .