At week @ , although there was no significant difference in the mean reduction of serum HBV DNA from baseline between LdT + ADV group and LAM + ADV group ( -@ vs -@ log@ IU/mL , P = @ ) , more patients in the LdT + ADV group had undetectable HBV DNA levels compared to those in the LAM + ADV group ( @ % vs @ % , P = @ ) .