Secondary outcomes were duration of cry or fuss ; number of cry or fuss episodes ; sleep duration of infant at @ , @ , and @ days , and @ and @ months ; maternal mental health ( Edinburgh postnatal depression subscale ) ; family functioning ( paediatric quality of life inventory ) , parent quality adjusted life years ( assessment of quality of life ) at @ and @ months ; infant functioning ( paediatric quality of life inventory ) at @ months ; infant faecal microbiota ( microbial diversity , colonisation with Escherichia coli ) , and calprotectin levels at @ month .