PPI + LLP was most effective in reducing GER episodes ( @ -LSB- @ -RSB- to @ -LSB- @ -RSB- , P < @ ) and esophageal acid exposure ( median -LSB- interquartile range -RSB- @ % -LSB- @ % -@ % -RSB- to @ % -LSB- @ % -@ % -RSB- , P = @ ) .