Changes in target-to-background ratio values from baseline were significantly greater in the pioglitazone group than in the glimepiride group ( -@ @ vs. @ @ , p = @ ) , as well as changes in high-sensitivity C-reactive protein ( pioglitazone vs. glimepiride group : median : -@ -LSB- interquartile range ( IQR ) : -@ to -@ -RSB- mg/l vs. @ -LSB- IQR : -@ to @ -RSB- mg/l , p = @ ) .