In a double-blind trial , patients were randomly assigned to echium oil ( intervention ( I ) group ; @ ml bis in die ( b.i.d. ) , @ mg/ml - linolenic acid ( ALA ) + @ mg/ml stearidonic acid ( SDA ) + @ mg/ml - linolenic acid ( GLA ) ) or n-@ FA deficient sunflower oil high oleic ( control ( C ) group ; @ ml b.i.d. ) additional to standard nutritional support during treatment .