Improvement in PVR and mean pulmonary artery pressure ( MPAP ) over a @-week period was significantly associated with improvement in RV FWLS ( r = @ , P = @ ; @ , P = @ respectively ) , LV global CS ( r = @ , P = @ ; r = @ , P = @ , respectively ) , and LV septal CS ( r = @ , P = @ ; r = @ , P = @ , respectively ) .