In breakfast meal test patients , lixisenatide reduced @-hour PPG versus placebo ( LS mean : -@ vs. -@ mg/dL -LSB- -@ vs. -@ mmol/L -RSB- ; p < @ ) and glucose excursion ( -@ vs. +@ mg/dL -LSB- -@ vs. +@ mmol/L -RSB- ) , and reduced @-hour glucagon , insulin , proinsulin , and C-peptide .