Changes of clinical symptoms and signs , fast blood glucose ( FBG ) , urinary albumin excretion rate ( UAER ) , beta@-microglobulin ( beta@-MG ) , monocyte chemotactic protein-@ ( MCP-@ ) , lymphocyte membrane cholesterol , propanediol ( MDA ) , PCO , @-hydroxydeoxy guanosine ( @-OHdG ) , superoxide dismutase ( SOD ) , CD@ + , CD@ + , CD@ + , and CD@ + / CD@ + were observed before and after treatment in two groups .