The respective changes in HbA@c were -@ % ( -@ mmol/mol ) and +@ % ( +@ mmol/mol ) ( difference -@ % -LSB- -@ mmol/mol -RSB- ) ( -LSB- @ % CI -@ % , -@ % -RSB- -LSB- -@ , -@ mmol/mol -RSB- ; p < @ ) ; respective changes in insulin dose were -@ U/day and +@ U/day ( difference -@ U/day -LSB- @ % CI -@ , -@ U/day -RSB- ; p < @ ) .