The most common treatment-related grade @ or @ adverse events in the afatinib group were rash or acne ( @ -LSB- @ % -RSB- of @ patients ) , diarrhoea ( @ -LSB- @ % -RSB- ) , and stomatitis or mucositis ( @ -LSB- @ % -RSB- ) , compared with neutropenia ( @ -LSB- @ % -RSB- of @ patients ) , vomiting ( @ -LSB- @ % -RSB- ) , and leucopenia ( @ -LSB- @ % -RSB- ) in the gemcitabine and cisplatin group .