Least squares ( LS ) mean change from baseline to endpoint ( week @ ) favored AOM versus placebo in PANSS total ( treatment difference , -@ -LSB- @ % CI , -@ to -@ -RSB- ; P < @ ) and CGI-S ( treatment difference , -@ -LSB- @ % CI , -@ to -@ -RSB- ; P < @ ) scores , as it did at all other timepoints through @ weeks ( all P @ ) .