The proportion of infants who required surgical closure of a patent ductus arteriosus was lower in the budesonide group than in the placebo group ( relative risk , stratified according to gestational age , @ ; @ % CI , @ to @ ; P = @ ) , as was the proportion of infants who required reintubation ( relative risk , stratified according to gestational age , @ ; @ % CI , @ to @ ; P = @ ) .