This prospective randomized controlled , open-labeled trial , with blinded end point evaluation ( PROBE design ) tested superiority of aspirin @ to @ mg/d plus clopidogrel @ mg/d ( A+C ) over warfarin therapy ( international normalized ratio @-@ ) in patients with ischemic stroke , transient ischemic attack , or peripheral embolism with plaque in the thoracic aorta > @ mm and no other identified embolic source .