One dose of Vi-CRM@ significantly increased concentrations of anti-Vi antibody in adults ( from @ U/mL -LSB- @ % CI @-@ -RSB- to @ U/mL -LSB- @-@ -RSB- ) , children ( @ U/mL -LSB- @-@ -RSB- to @ U/mL -LSB- @-@ -RSB- ) , and older infants ( @ U/mL -LSB- @-@ -RSB- to @ U/mL -LSB- @-@ -RSB- ) .