The commonest grade @-@ toxic effects were neutropenia ( @ -LSB- @ % -RSB- patients in the chemotherapy group , @ -LSB- @ % -RSB- patients in the sequential chemoimmunotherapy group , and @ -LSB- @ % -RSB- patients in the concurrent chemoimmunotherapy group ; fatigue ( @ -LSB- @ % -RSB- in the chemotherapy group , @ -LSB- @ % -RSB- in the sequential chemoimmunotherapy group , and @ -LSB- @ % -RSB- in the concurrent chemoimmunotherapy group ) ; and pain ( @ -LSB- @ % -RSB- patients in the chemotherapy group , @ -LSB- @ % -RSB- in the sequential chemoimmunotherapy group , and @ -LSB- @ % -RSB- in the concurrent chemoimmunotherapy group ) .