There was significantly synergistic effect of combination of telmisartan with rosuvastatin on reducing carotid imtima-media thickness ( IMT ) , Th@ cells frequency , IL-@ , IL-@ , IL-@ , tumor necrosis factor ( TNF ) - , expression of retinoic acid receptor-related orphan receptor ( ROR ) t mRNA , Th@/Treg ratio , IL-@ , IL-@ , IFN - , hsCRP , and MCP-@ , and increasing Treg cells frequency , IL-@ , transforming growth factor ( TGF ) -@ , and expression of forkhead/winged helix transcription factor ( Foxp@ ) mRNA ( all P < @ ) .