The relative effect of apixaban compared with aspirin was similar in men and women for both ischemic stroke ( women , @ % versus @ % ; hazard ratio , @ ; @ % confidence interval , @-@ @ ; men , @ % versus @ % ; hazard ratio , @ ; @ % confidence interval , @-@ @ ; Pint = @ ) and major bleeding ( women , @ % versus @ % ; hazard ratio , @ ; @ % confidence interval , @-@ @ ; men , @ % versus @ % ; hazard ratio , @ ; @ % confidence interval , @-@ @ ; Pint = @ ) .