After the @-month study period , patients in the treatment group showed significantly improved left ventricular end-diastolic diameter ( P = @ ) , left ventricular end-systolic diameter ( P = @ ) , left ventricular ejection fraction ( P = @ ) , and left atrial diameter ( P = @ ) values , and their serum N-terminal prohormone of brain natriuretic peptide ( P = @ ) and high-sensitive C-reactive protein ( P = @ ) concentrations were significantly improved compared with the control group .