By the end of the study , the annualised relapse rate was higher in patients assigned to placebo ( @ -LSB- @ % CI @-@ @ -RSB- ) than in those assigned to teriflunomide @ mg ( @ -LSB- @-@ @ -RSB- ; p = @ ) or teriflunomide @ mg ( @ -LSB- @-@ @ -RSB- ; p = @ ) .