A better therapeutic response was found in group A patients , as shown by higher objective response rate ( ORR ) and clinical benefit rate ( CBR ) values in group A versus group B ( ORR , @ % -LSB- @ % confidence interval ( CI ) , @ % -@ % -RSB- vs @ % -LSB- @ % CI , @ % -@ % -RSB- , ( @ ) = @ , P < @ ; CBR , @ % -LSB- @ % CI , @ % -@ % -RSB- vs @ % -LSB- @ % CI , @ % -@ % -RSB- , ( @ ) = @ , P < @ ) .