In this study , we sought to examine the hypothesis that neoadjuvant chemotherapy ( NAC ) is a better approach with improved prognosis and outcomes after laparoscopical radical hysterectomy ( LRH ) on patients with cervical cancer and to elucidate the potential roles of the p@ : miR-@a : E@F@ and the p@ : miR-@ : Mdm@ signaling pathways in this therapy .