The UHC patients treated with PDT plus S-@ showed higher @-year survival rate compared with the patients treated with PDT alone ( @ % versus @ % , P = @ ) and prolonged overall survival ( median @ months , @ % confidence interval -LSB- CI -RSB- : @-@ @ , versus @ months , @ % CI : @-@ , P = @ , hazard ratio -LSB- HR -RSB- , @ ; @ % CI : @-@ @ ) .