Haematological and non-haematological toxic effects that were significantly more common in the carboplatin group than in the no-carboplatin group included grade @ or @ neutropenia ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , grade @ or @ anaemia ( @ -LSB- @ % -RSB- vs one -LSB- < @ % -RSB- ) , grade @ or @ thrombocytopenia ( @ -LSB- @ % -RSB- vs one -LSB- < @ % -RSB- ) , and grade @ or @ diarrhoea ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) ; carboplatin was more often associated with dose discontinuations ( @ -LSB- @ % -RSB- with carboplatin and @ -LSB- @ % -RSB- without carboplatin ; p = @ ) .