l effikaċja ta  nateglinide kienet anqas minn dik ta  metformin f monoterapija (tnaqqis ta  hba1c () b metformin 500 mg tlett darbiet kuljum b monoterapija  1 23 [95 ci  1 48  0 99] u b nateglinide 120 mg tlett darbiet kuljum b monoterapija  0 90 [95 ci  1 14  0 66])