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Academy of Finland; The Danish Interdisciplinary Research Council; The Health Foundation (Helsefonden); The Ministry for Higher Education; The National Program for Research Infra- structure 2007 (grant 09-063256); The March of Dimes Birth Defects Foundation; The Swedish Foundation for Strategic Re- search (SSF); Unilever Discover Colworth; Universite´ Paris 13; University of Calabria; University of Tartu (grant SP1GVAR- ENG); Velux Foundation; VU University’s Institute for Health + and Care Research (EMGO ) and Neuroscience Campus Amsterdam (NCA); Wellcome Trust (grant 084762, 085475 and 087436). Funding to pay the Open Access publication charges for this article was provided by IDEAL (FP7- HEALTH-2010-two-stage-259679).

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