) Gene/longevity associa- tion studies at four autosomal loci (REN, THO, PARP, SOD

). Eur J Hum Genet

:

–

De Benedictis G, Tan Q, Jeune B, Christensen K, Ukraintseva SV, Bonafe M, Franceschi C, Vaupel JW and Yashin AI (

) Recent advances in human gene-longevity association studies. Mech Ageing Dev

:

–

Goode EL, Ulrich CM and Potter JD (

) Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev

:

–

Hasty P (

) The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice. Mech Ageing Dev

:

–

Hasty P, Campisi J, Hoeijmakers J, Steeg Hvan and Vijg J (

) Aging and genome maintenance: lessons from the mouse? Science

:

–

Hochberg Y (

) A sharper Bonferroni procedure for multiple tests of significance. Biometrika

:

–

Hoeijmakers JH (

) Genome maintenance mechanisms for preventing cancer. Nature

:

–

Jones IM, Galick H, Kato P, Langlois RG, Mendelsohn ML, Murphy GA, Pleshanov P, Ramsey MJ, Thomas CB, Tucker JD, Tureva L, Vorobtsova I and Nelson DO (

) Three somatic genetic biomarkers and covariates in radiation- exposed Russian cleanup workers of the Chernobyl nuclear reactor

–

years after exposure. Radiat Res

:

–

King CM, Gillespic ES, M

enna PG, Barnett YA (

) An investigation of mutation as a function of age in humans. Mutat Res

:

–

King CM, Bristow-Craig HE, Gillespie ES and Barnett YA (

) In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy

- to

-year-old humans. Mutat Res

:

–

Krichevsky S, Pawelec G, Gural A, Effros RB, Globerson A, Yehuda DB and Yehuda AB (

) Age related microsatel- lite instability in T cells from healthy individuals. Exp Gerontol

:

–

Lewis SJ and Brunner EJ (

) Methodological problems in genetic association studies of longevity – the apolipoprotein E gene as an example. Int J Epidemiol

:

–

Lucas JN, Deng W, Moore D, Hill F, Wade M, Lewis A, Sailes F, Kramer C, Hsieh A and Galvan N (

) Background ionizing radiation plays a minor role in the production of chromosome translocations in a control population. Int J Radiat Biol

:

–

Lunn RM, Langlois RG, Hsieh LL, Thompson CL and Bell DA (

) XRCC

polymorphisms: effects on aflatoxin B

-DNA adducts and glycophorin A variant frequency. Cancer Res

:

–

Marnett LJ (

) Oxyradicals and DNA damage. Carcino- genesis

:

–

Marnett LJ and Plastaras JP (

) Endogenous DNA damage and mutation. Trends Genet

:

–

Mohrenweiser HW, Wilson DM and Jones IM (

) Challenges and complexities in estimating both the functional

De Benedictis G, Carotenuto L, Carrieri G, Luca MDe, Falcone E, Rose G, Cavalcanti S, Corsonello F, Feraco E, Baggio G, Bertolini S, Mari D, Mattace R, Yashin AI, Bonafe M and Franceschi C (

) Gene/longevity associa- tion studies at four autosomal loci (REN, THO, PARP, SOD

). Eur J Hum Genet

:

–

De Benedictis G, Tan Q, Jeune B, Christensen K, Ukraintseva SV, Bonafe M, Franceschi C, Vaupel JW and Yashin AI (

) Recent advances in human gene-longevity association studies. Mech Ageing Dev

:

–

Goode EL, Ulrich CM and Potter JD (

) Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev

:

–

Hasty P (

) The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice. Mech Ageing Dev

:

–

Hasty P, Campisi J, Hoeijmakers J, Steeg Hvan and Vijg J (

) Aging and genome maintenance: lessons from the mouse? Science

:

–

Hochberg Y (

) A sharper Bonferroni procedure for multiple tests of significance. Biometrika

:

–

Hoeijmakers JH (

) Genome maintenance mechanisms for preventing cancer. Nature

:

–

Jones IM, Galick H, Kato P, Langlois RG, Mendelsohn ML, Murphy GA, Pleshanov P, Ramsey MJ, Thomas CB, Tucker JD, Tureva L, Vorobtsova I and Nelson DO (

) Three somatic genetic biomarkers and covariates in radiation- exposed Russian cleanup workers of the Chernobyl nuclear

impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat Res

:

–

Morley A (

) Somatic mutation and ageing. Ann NY Acad Sci

:

–

Muiras ML, Muller M, Schachter F and Burkle A (

) Increased poly(ADP-ribose) polymerase activity in lympho- blastoid cell lines from centenarians. J Mol Med

:

–

Neri S, Cattini L, Facchini A, Pawelec G and Mariani E (

) Microsatellite instability in in vitro ageing of T lymphocyte clones. Exp Gerontol

:

–

Pesch B, Dusing R, Rabstein S, Harth V, Grentrup D, Bruning T, Landt O, Vetter H and Ko YD (

) Polymorphic metabolic susceptibility genes and longevity: a study in octogenarians. Toxicol Lett

:

–

Price EA, Bourne SL, Radbourne R, Lawton PA, Lamerdin J, Thompson LH and Arrand JE (

) Rare microsatellite polymorphisms in the DNA repair genes XRCC

, XRCC

and XRCC

associated with cancer in patients of varying radiosensitivity. Somat Cell Mol Genet

:

–

Ramsey MJ, Moore DH, Briner JF, Lee DA, Olsen L, Senft JR and Tucker JD (

) The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting. Mutat Res

:

–

Relton CL, Daniel CP, Hammal DM, Parker L, Tawn EJ and Burn J (

) DNA repair gene polymorphisms, pre-natal factors and the frequency of somatic mutations in the glycophorin-A gene among healthy newborns. Mutat Res

:

–

Ruttan CC and Glickman BW (

) Coding variants in human double-strand break DNA repair genes. Mutat Res

:

–

Savas S, Kim DY, Ahmad MF, Shariff M and Ozcelik H (

) Identifying functional genetic variants in DNA repair pathway using protein conservation analysis. Cancer Epidemiol Biomarkers Prev

:

–

Shen MR, Jones IM and Mohrenweiser H (

) Nonconser- vative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res

:

–

Slupphaug G, Kavli B and Krokan HE (