,

–

Kong, Q.P., Bandelt,H.J., Sun, C.,Yao, Y.G., Salas,A., Achilli, A., Wang,C.Y., Zhong,L., Zhu, C.L.,Wu,S.F.,Torroni,A.,Zhang,Y.P.,

Updating th

as

sianm

NA phylog- eny: a prerequisite for the identification of pathogenic mutations. Hum. Mol. Genet.

,

–

Koropatnick, T.A., Kimbell, J., Chen, R., Grove, J.S., Donlon, T.A., Masaki, K.H., Rodriguez, B.L., Willcox, B.J., Yano, K., Curb, J.D.,

A prospective study of high-density li- poprotein cholesterol, cholesteryl ester transfer protein gene variants, and healthy aging in very old Japanese–American men. J. Gerontol. A Biol. Sci. Med. Sci.

,

–

Korpelainen, H.,

Genetic maternal effects on human life span through the inher- itance of mitochondrial DNA. Hum. Hered.

,

–

Kumar, S., Tamura, K., Nei, M.,

MEGA

: integrated software for Molecular Evolu- tionary Genetics Analysis and sequence alignment. Brief. Bioinform.

,

–

Lenaz, G., Fato, R., Genova, M.L., Bergamini, C., Bianchi, C., Biondi, A.,

Mitochon- drial complex I: structural and functional aspects. Biochim. Biophys. Acta

,

–

Li, H., Cai, X., Winograd-Cort, E.R., Wen, B., Cheng, X., Qin, Z., Liu, W., Liu, Y., Pan, S., Qian, J., Tan, C.C., Jin, L.,

Mitochondrial DNA diversity and population differ- entiation in southern East Asia. Am. J. Phys. Anthropol.

,

–

Li, Y., Wang, W.J., Cao, H., Lu, J., Wu, C., Hu, F.Y., Guo, J., Zhao, L., Yang, F., Zhang, Y.X., Li, W., Zheng, G.Y., Cui, H., Chen, X., Zhu, Z., He, H., Dong, B., Mo, X., Zeng, Y., Tian, X.L.,

Genetic association of FOXO

A and FOXO

A with longevity trait in Han Chi- nese populations. Hum. Mol. Genet.

,

–

Niemi, A.K., Hervonen, A., Hurme, M., Karhunen, P.J., Jylha, M., Majamaa, K.,

Mi- tochondrial DNA polymorphisms associated with longevity in a Finnish popula- tion. Hum. Genet.

,

–

Niemi, A.K., Moilanen, J.S., Tanaka, M., Hervonen, A., Hurme, M., Lehtimaki, T., Arai, Y., Hirose, N., Majamaa, K.,

A combination of three common inherited mito- chondrial DNA polymorphisms promotes longevity in Finnish and Japanese sub- jects. Eur. J. Hum. Genet.

,

–

Ordovas, J.M.,

Gender, a significant factor in the cross talk between genes, envi- ronment, and health. Gend. Med.

(Suppl. B), S

–S

Pablos-Mendez, A.,Mayeux, R.,Ngai,C.,Shea,S.,Berglund, L.,

Associationof ap

polymorphism with plasma lipid levels in a multiethnic elderly population. Arter- ioscler. Thromb. Vasc. Biol.

,

–

Pan, H., Kong, Q.P., Cheng, Y.T., Lian, S.G., Yang, J., Gao, S.J., Xu, L.Y., Zhang, Y.P.,

Absence ofassociationbetweenmitochondria

NA C

T polymorphism andlon- gevity in a Han Chinese population. Exp. Gerontol.

,

–

Paolisso, G., Gambardella, A., Ammendola, S., Tagliamonte, M.R., Rizzo, M.R., Capurso, A., Varricchio, M.,

Preserved antilipolytic insulin action is associated with a less atherogenic plasma lipid profile in healthy centenarians. J. Am. Geriatr. Soc.

,

–

Rontu, R., Ojala, P., Hervonen, A., Goebeler, S., Karhunen, P.J., Nikkila, M., Kunnas, T., Jylha, M., Eklund, C., Hurme, M., Lehtimaki, T., 2006. Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nona-

Jylha, M., Eklund, C., Hurme, M., Lehtimaki, T.,

Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nona- genarians. Clin. Endocrinol. (Oxf)

,

–

Rosa, A., Fonseca, B.V., Krug, T., Manso, H., Gouveia, L., Albergaria, I., Gaspar, G., Correia, M., Viana-Baptista, M., Simoes, R.M., Pinto, A.N., Taipa, R., Ferreira, C., Fontes, J.R., Silva, M.R., Gabriel, J.P., Matos, I., Lopes, G., Ferro, J.M., Vicente, A.M., Oliveira, S.A.,

Mitochondrial haplogroup H

is protective for ischemic stroke in Portuguese patients. BMC Med. Genet.

,

Ross, O.A.,M

ormack, R.,Curran,M.D., Duguid, R.A., Barnett, Y.A.,Rea, I.M., Middleton, D.,

Mitochondrial DNA polymorphism: its role in longevity of the Irish pop- ulation. Exp. Gerontol.

,

–

Santoro, A., Salvioli, S., Raule, N., Capri, M., Sevini, F., Valensin, S., Monti, D., Bellizzi, D., Passarino, G., Rose, G., De Benedictis, G., Franceschi, C.,

Mitochondrial DNA involvement in human longevity. Biochim. Biophys. Acta

,

–

Shryock, H.S., Siegel, J.S.,Stockwell,E.G.,

The Methods and Materials of Demogra- phy, Condensed ed. Academic Press, New York. Sont,J.K.,Vandenbroucke,J.P.,

Life expectancyandmitochondria

NA.Dowe in- herit longevity from our mother's mitochondria? J. Clin. Epidemiol.

,

–

Tanaka, M.,

Mitochondrial genotypes and cytochrome b variants associated with longevity or Parkinson's disease. J. Neurol.

(Suppl.

), II

–II

Tanaka, M., Gong, J.S., Zhang, J., Yoneda, M., Yagi, K.,

Mitochondrial genotype as- sociated with longevity. Lancet

,

–

Tanaka, M., Cabrera, V.M., Gonzalez, A.M., Larruga, J.M., Takeyasu, T., Fuku, N., Guo, L.J., Hirose,R.,Fujita,Y.,Kurata,M.,Shinoda, K.,Umetsu,K.,Yamada,Y.,Oshida,Y.,Sato, Y., Hattori, N., Mizuno, Y., Arai, Y., Hirose, N., Ohta, S., Ogawa, O., Tanaka, Y., Kawa- mori, R., Shamoto-Nagai, M., Maruyama, W., Shimokata, H., Suzuki, R., Shimodaira, H.,

Mitochondrial genome variation in eastern Asia and the peopling of Japan. Genome Res.

,

–

Tharaphan, P., Chuenkongkaew, W.L., Luangtrakool, K., Sanpachudayan, T., Suktitipat, B., Suphavilai, R., Srisawat, C., Sura, T., Lertrit, P.,

Mitochondrial DNA hap- logroup distribution in pedigrees of Southeast Asian G

A Leber hereditary optic neuropathy. J. Neuroophthalmol.

,

–

Turnpenny, P.D., Ellard, S.,

Emery's Elements of Medical Genetics,

th ed. Else- vier/Churchill Livingstone, Edinburgh; New York. van der Walt, J.M., Nicodemus, K.K., Martin, E.R., Scott, W.K., Nance, M.A., Watts, R.L., Hubble, J.P., Haines, J.L., Koller, W.C., Lyons, K., Pahwa, R., Stern, M.B., Colcher, A., Hiner, B.C., Jankovic, J., Ondo, W.G., Allen Jr., F.H., Goetz, C.G., Small, G.W., Masta- glia,F.,Stajich,J.M.,M

aurin,A.C.,Middleton,L.T.,Scott,B.L.,Schmechel,D.E.,Peri- cak-Vance, M.A., Vance, J.M.,