4.1 26.0 3.3 25.2 1 +1 2.8 24.8 3.3 Education, >8 yrsa 14 (13.9) 44 (19.2) 28 (23.9) 9 (13.4) 19 (17.0) 18 (34.0) Smokers, ever 57 (56.4) 121 (52.4) 56 (47.9) 56 (83.6) 91 (81.3) 42 (80.8) Alcohol, >10 units/week 8 (8.7) 29 (13.6) 16 (15.0) 24 (40.0) 39 (37.9) 18 (38.3) b Self-reported diseases Diabetes 6 (5.9) 10 (4.3) 5 (4.2) 2 (2.9) 11 (9.7) 6 (11.3) Hypertension 33 (32.7) 66 (28.6) 33 (28.0) 11 (16.2) 26 (23.2) 14 (26.4) c Other cardiovascular13(12.9)31(13.4 )17(14 .4 )10(14 .7 )22(19 .5 )7(13 .2 ) Stroke3(3 .0 )12(5 .2 )5(4 .2 )7(10 .3 )5(4 .4 )6(11 .3 ) d Respiratory9(8 .9 )27(11 .7 )12(10 .2 )17(25 .0 )17(15 .0 )14(26 .4 ) Poor/very poor self-rated health e 7 (7.1) 17 (7.5) 11 (9.3) 3 (4.8) 3 (2.8) 6 (11.3) No statistically significant differences among genotypes if not otherwise stated. Differences were tested with Logistic regression for categorical data and with multivariate linear regression for continuous data with the DD genotype as reference, controlling for age of the participants. Twins from intact pairs were analyzed as clusters of two in the multivariate models. aMales, DI: p < 0.02, II: p < 0.02 bParticipants were asked if a physician had ever told them that they suffered from any of the mentioned diseases. cAngina, myocardial infarction or heart failure dChronic bronchitis or asthma Cognitive Abilities surveys were comparable in the three ACE genotypes (Table 3). Although not statistically significant, the proportion of individuals with a score below 24 was approximately seven percent higher in participants with the II genotype of The MMSE-test was completed by 674 persons with a median score of 27.0 (quartiles 24.0-28.0). The median test scores and the mean difference in scores between the two TABLE 2. Physical abilities and ACE genotype Females Males ACE genotype II ID DD II ID DD Self-reported physical abilities in 1997 Median strength score (quartiles) 3.4 (2.5, 3.7) 3.5 (2.6, 3.7) 3.3 (2.5, 3.7) 3.5 (2.5, 3.7) 3.5 (3.2, 3.8) 3.5 (2.9, 3.7) N 101 231 117 68 113 53 Self-reported physical abilities in 1999a Median strength score (quartiles) 3.3 (2.5, 3.6) 3.4 (2.7, 3.5) 3.4 (2.5, 3.5) 3.5 (2.7, 3.6) 3.4 (2.6, 3.6) 3.5 (2.7, 3.7) Mean endurance score (SD)b 4.7 (1.1) 4.7 (1.1) 4.8 (1.0) 4.2 (1.2) 4.4 (1.2) 4.4 (1.4) N 73 173 89 54 91 42 Relative difference in self-reported abilities1997 to1999 Mean relative strength score difference(SD)0 .05(0 .2 )0 .05(0 .2 )0 .02(0 .2 )0 .07(0mu, Holm N, Sorensen TIA, Harvald B, Vaupel JW. The heritability of human longevity: a population-based study of Danish twin pairs born between 1870 and 1900. Hum Genet. 2000; 106: 659-661.

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Chapman J, Wang N, Treves TA, Korczyn AD, Bornstein NM. ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patientsThere is not enough context to understand what the text is referring to. Please provide more information.