All AD cases met criteria for either probable (National Institute of Neurology and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association [now known as the Alzheimer's Association] [NINCDS-ADRDA], Diagnostic and Statistical Manual of Mental Disorders, 4th Ed [DSM-IV]) or definite (Consortium to Establish a registry for Alzheimer's Disease [CERAD]) AD. All elderly controls screened for dementia using the Mini Mental State Examination (MMSE) or Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) were determined to be free from dementia at neuropathological examination or had a Braak score of 2.5 or lower. All studies used the Illumina 610 QuadChip, except the Mayo study which used the Illumina HumanHap300 chip (Carrasquillo et al., 2009).

Table 1: Summary of sample information

Dataset Sample AD status Gender Genotyping Mean AAD Origin size (AD/controls) (male/female) chip (AD/controls)