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Table S3 Lack of association with exceptional longevity of vari- ants in HRAS1 and LASS1 in the major population strata

Supporting Information

Additional Supporting Information may be found in the online version of this article:

Table S4 Association of combinations of haplotypes in HRAS1, and LASS1 with exceptional longevity

Fig. S1 Haplotype blocks in APOE, HRAS1, and LASS1. Haplo- type blocks for the three genes were examined using Haploview after stratifying the populations using Structure assignment probabilities of 0.8 and 0.9 (in parentheses below) for European origin. A – Georgia (0.9), B – Georgia (0.8), C – Louisiana (0.9), and D – Louisiana (0.8). Among the differences between the two populations, the large haplotype block in HRAS1 that is evident in the Louisiana population at 0.9 and 0.8 assignment probabilities is only apparent in Georgia at 0.9 assignment prob- ability, and the haplotype block seen in LASS1 in the Louisiana population is not apparent in the Georgia population. No tag SNP in the haplotype blocks were identified.

Table S8 Genotyped loci

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Table S2 APOE association with exceptional longevity in major population strata