PANTHER version protein sequence and function evolution data with expanded tation of biological pathways. Nucleic Acids Res.

(Database D

–D

Nevins, J.R.,

The Rb/E

F pathway and cancer. Hum. Mol. Genet.

–

Newman, A.B., Walter, S., Lunetta, K.L., Garcia, M.E., Slagboom, Christensen, K., Arnold, A.M., Aspelund, T., Aulchenko, Y.S., min, E.J., Christiansen, L., D’Agostino, R.B., Sr., Fitzpatrick, Franceschini, N., Glazer, N.L., Gudnason, V., Hofman, A., Kaplan, Karasik, D., Kelly-Hayes, M., Kiel, D.P., Launer, L.J., K.D., Massaro, J.M., Miljkovic, I., Nalls, M.A., Hernandez, D., B.M., Rivadeneira, F., Rotter, J., Seshadri, S., Smith, A.V., K.D., Tiemeier, H., Uh, H.W., Uitterlinden, A.G., Vaupel, J.W., ston, J., Westendorp, R.G., Harris, T.B., Lumley, T., van Duijn, Murabito, J.M.,

A meta-analysis of four genome-wide tion studies of survival to age

years or older: The Cohorts for and Aging Research in Genomic Epidemiology Consortium. J. tol. A Biol. Sci. Med. Sci.

,

–

Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M.D., Bochud, M., L., Najjar, S.S., Zhao, J.H., Heath, S.C., Eyheramendy, S., Papadakis, Voight, B.F., Scott, L.J., Zhang, F., Farrall, M., Tanaka, T., Wallace, Chambers, J.C., Khaw, K.T., Nilsson, P., van der Harst, P., Polidoro, Grobbee, D.E., Onland-Moret, N.C., Bots, M.L., Wain, L.V., Elliott, Teumer, A., Luan, J., Lucas, G., Kuusisto, J., Burton, P.R., Hadley, M

rdle, W.L., Brown, M., Dominiczak, A., Newhouse, S.J., N.J., Webster, J., Zeggini, E., Beckmann, J.S., Bergmann, S., Lim, Song, K., Vollenweider, P., Waeber, G., Waterworth, D.M., Yuan, Groop, L., Orho-Melander, M., Allione, A., Di Gregorio, A., Guarrera, Panico, S., Ricceri, F., Romanazzi, V., Sacerdote, C., Vineis, P., I., Sandhu, M.S., Luben, R.N., Crawford, G.J., Jousilahti, P., Perola, Boehnke, M., Bonnycastle, L.L., Collins, F.S., Jackson, A.U., K.L., Stringham, H.M., Valle, T.T., Willer, C.J., Bergman, R.N., M.A., Doring, A., Gieger, C., Illig, T., Meitinger, T., Org, E., Pfeufer, Wichmann, H.E., Kathiresan, S., Marrugat, J., O’Donnell, C.J., S.M., Siscovick, D.S., Subirana, I., Freimer, N.B., Hartikainen, M

arthy, M.I., O’Reilly, P.F., Peltonen, L., Pouta, A., de Jong, Snieder, H., van Gilst, W.H., Clarke, R., Goel, A., Hamsten, A., J.F., Seedorf, U., Syvanen, A.C., Tognoni, G., Lakatta, E.G., Sanna, Scheet, P., Schlessinger, D., Scuteri, A., Dorr, M., Ernst, F., Felix, Homuth, G., Lorbeer, R., Reffelmann, T., Rettig, R., Volker, U., Galan, Gut, I.G., Hercberg, S., Lathrop, G.M., Zelenika, D., Deloukas, Soranzo, N., Williams, F.M., Zhai, G., Salomaa, V., Laakso, M., R., Forouhi, N.G., Volzke, H., Uiterwaal, C.S., van der Schouw, Numans, M.E., Matullo, G., Navis, G., Berglund, G., Bingham, Kooner, J.S., Connell, J.M., Bandinelli, S., Ferrucci, L., Watkins, Spector, T.D., Tuomilehto, J., Altshuler, D., Strachan, D.P., Laan, Meneton, P., Wareham, N.J., Uda, M., Jarvelin, M.R., Mooser, V., lander, O., Loos, R.J., Elliott, P., Abecasis, G.R., Caulfield, M., P.B.,

Genome-wide association study identifies eight loci with blood pressure. Nat. Genet.

,

–

Pawlikowska, L., Hu, D., Huntsman, S., Sung, A., Chu, C., Chen, Joyner, A.H., Schork, N.J., Hsueh, W.C., Reiner, A.P., Psaty,

S

Maiuri, M.C., Tasdemir, E., Criollo, A., Morselli, E., Vicencio, J.M., Carnuccio, R., Kroemer, G.,

Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ.

,

–

M

ue, M., Vaupel, J.W., Holm, N., Harvald, B.,

Longevity is moderately heritable in a sample of Danish twins born

–

J. Gerontol.

, B

–B

Ménard, C., Hein, P., Paquin, A., Savelson, A., Yang, X.M., Lederfein, D., Barnabé-Heider, F., Mir, A.A., Sterneck, E., Peterson, A.C., Johnson, P.F., Vinson, C., Miller, F.D.,

An essential role for a MEK-C/ EBP pathway during growth factor-regulated cortical neurogenesis. Neuron

,

–

Mi, H., Guo, N., Kejariwal, A., Thomas, P.D.,

PANTHER version

: protein sequence and function evolution data with expanded represen- tation of biological pathways. Nucleic Acids Res.

(Database issue), D

–D

Nevins, J.R.,

The Rb/E

F pathway and cancer. Hum. Mol. Genet.

,

–

Newman, A.B., Walter, S., Lunetta, K.L., Garcia, M.E., Slagboom, P.E., Christensen, K., Arnold, A.M., Aspelund, T., Aulchenko, Y.S., Benja- min, E.J., Christiansen, L., D’Agostino, R.B., Sr., Fitzpatrick, A.L., Franceschini, N., Glazer, N.L., Gudnason, V., Hofman, A., Kaplan, R.,

centenarians. Proc. Natl. Acad. Sci. U. S. A.

,

–

Gerdes, L.U., Jeune, B., Ranberg, K.A., Nybo, H., Vaupel, J.W.,

Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle- aged men: apolipoprotein E gene is a “frailty gene,” not a “longevity gene.Genet. Epidemiol.

,

–

Goga, A., Yang, D., Tward, A.D., Morgan, D.O., Bishop, J.M.,

Inhibition of CDK

as a potential therapy for tumors over-expressing MYC. Nat. Med.

,

–

Herskind, A.M., M

ue, M., Holm, N.V., Sørensen, T.I., Harvald, B., Vaupel, J.W.,

The heritability of human longevity: a population- based study of

Danish twin pairs born

–

Hum. Genet.

,

–

Hirai, H., Launey, T., Mikawa, S., Torashima, T., Yanagihara, D., Kasaura, T., Miyamoto, A., Yuzaki, M.,

New role of delta

-glutamate receptors in AMPA receptor trafficking and cerebellar function. Nat. Neurosci.

,

–

Inestrosa, N.C., Arenas, E.,

Emerging roles of Wnts in the adult nervous system. Nat. Rev. Neurosci.

,

–

Johnson, S., Halford, S., Morris, A.G., Patel, R.J., Wilkie, S.E., Hardcastle, A.J., Moore, A.T., Zhang, K., Hunt, D.M.,

Genomic organisation and alternative splicing of human RIM

, a gene implicated in auto- somal dominant cone-rod dystrophy (CORD

). Genomics

,

–

Joshi, K., Lee, S., Lee, B., Lee, J.W., Lee, S.K.,

LMO

controls the balance between excitatory and inhibitory spinal V

interneurons. Neu- ron

,

–

Keeble, T.R., Halford, M.M., Seaman, C., Kee, N., Macheda, M., Ander- son, R.B., Stacker, S.A., Cooper, H.M.,