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x Dato S, Carotenuto L, De Benedictis G (

) Genes and longevity: a genetic-demographic approach reveals sex- and age-specific gene effects not shown by the case– control approach (APOE and HSP

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De Benedictis G, Franceschi C (

) The unusual genetics of human longevity. Sci Aging Knowl Environ

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De Benedictis G, Franceschi C (

) The unusual genetics human longevity. Sci Aging Knowl Environ

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) Sex-specific gevity associations defined by Tyrosine Insulin-Insulin Growth Factor

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p

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) Do men and women different trajectories to reach extreme longevity? Clin Exp Res

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) Secreted protein in sera and CSF: implication for cleavage in release of Klotho protein from cell FEBS Lett

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Kawano K, Ogata N, Chiano M, Molloy H, Kleyn P, TD, Uchida M, Hosoi T, Suzuki T, Orimo H, Inoue Nabeshima Y, Nakamura K, Kuro-o M, Kawaguchi (

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) Klotho as a regulator of oxidative stress senescence. Biol Chem

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Acknowledgments Thisworkwassupportedby:thePRRIITT program of the Emilia-Romagna Region (and Fondi Strutturali Obiettivo 2); Italian Ministry of Health Grant ‘‘Progetto Finalizzato (cid:2)Studio delle differenze uomo-donna nei mecca- nismi patogenetici delle malattie cardiovascolari(cid:3)‘‘to CF; Roberto and Cornelia Pallotti Legacy for Cancer Research GrantstoCFandSS.UniversityofBologna‘‘ProgettiStrategici’’ 2006 grant (‘‘p53 e patologie non neoplastiche nell’anziano: uno studio multidisciplinare sul ruolo del polimorfismo al codone 72 del gene TP53’’) to SS.

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