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talia

LSpatients.Neurobiol.Aging [epub ahead of print].

Considering the complexity of the mechanisms lead- ing to transcriptional and translational regulation of VEGF expression, additional polymorphisms (also located within the VEGF coding region) may be responsible for the pos- itive association with long term aging. Furthermore, this study opens the question about the role of other angiogenic factors striking similarity to VEGF on successful aging; in fact, angiogenin and progranulin have been recently associ- ated to neurodegenerative disorders and represent molecules with important neuroprotective activities (Baker et al., 2006;

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