In light of the recent progress in understanding the biomedical significance of SHC1 the SNPs documented here will be useful not only for studying associations between specific SNPs and SHC1-related diseases but also as a catalogue of SNPs among Japanese centenarians.

Acknowledgements We greatly appreciate the time and assistance given to us by the centenarians and their family members. This study could not have been performed without their kind cooper- ation.

References

Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, Nicoletti I, Grignani F, Pawson T, Pelicci PG (1992) A