Supporting Information

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Fig. S1 Scatterplot of the first two principal component scores based on the 229 SNPs (MAF > 0.01) identified in the 1291 mtDNA analyzed sequences.

Table S1. a and b. Haplogroup distribution in males and females.

Table S2. List of all the mutations identified in our sample by the complete mtDNA sequencing.

Table S3. mtDNA mutations found in our study and previously associated with diseases.

Table S4. Distribution of 90+ and controls from different centers in the GEHA project.

Table S6. Modified primer pairs for complete resequencing.