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Fig 2. Comparison of the promoter activity of the alleles of G190C polymorphism using HSPA1A 5’-flanking 488 bp fragment. The pro- moter activity was examined using a luciferase reporter system in hu- man lung carcinoma A549 cells. The data are expressed as mean 6 SD of5independent experiments.Theblankandgridbarsindicatethecon- trol and heat-inducible levels of luciferase activities expressed as per- centages of the activity of G190C alleles. RLA, the ratio of firefly luciferase activity to Renilla luciferase activity.

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