What is the impact of p53 on aging and cellular senescence?
p53 对衰老和细胞衰老有何影响？
p53 is a protein involved in stress responses and tumor suppression. Dysregulation of p53 can lead to cellular senescence, a state of irreversible cell cycle arrest, which contributes to aging. Modulating p53 activity may influence aging outcomes.
p53 是一种参与应激反应和肿瘤抑制的蛋白质。p53 失调可导致细胞衰老，这是一种不可逆的细胞周期停滞状态，从而导致衰老。调节 p53 活性可能会影响衰老结果。