What are the pharmacopeia requirements for melting point determination?
藥典對熔點測定有哪些需求？
Pharmacopeia requirements for melting point determination at a glance include:  Use capillaries with outer diameters ranging from 1.3–1.8 mm and wall thicknesses from 0.1– 0.2 mm. Apply a constant heating rate of 1°C/min. If not otherwise stated, the temperature is recorded point C when no solid substance is left (which corresponds to the clear point). Pharmacopeias such as the United States Pharmacopeia (USP) require the determination of the melting range, where points A (corresponds to collapse point) and C are used for temperature determination. The recorded temperature represents the temperature of the heating stand, which can be an oil bath or a metal block, in which the thermocouple is positioned.
Learn more about how to achieve compliance to local and international pharmacopoeias for melting point determination
迅速瞭解藥典熔點測定需求：  使用外徑範圍 1.3 至 1.8 毫米且壁厚度 0.1 至 0.2 毫米的毛細管。加熱速率維持在 1°C/分。若無另外表示，在沒有留下固態物質下 (相當於澄點)，溫度是記錄於 C 點。例如美國藥典 (USP) 要求的熔點測定範圍，是以 A 點 (相當於崩潰點) 和 C 點作為溫度測定。記下的溫度代表加熱站的溫度，加熱站是放置熱電偶的地方，可以為油槽或金屬塊。
進一步瞭解如何符合當地及全球藥典熔點測定合規性