Hvilke forskellige typer vand anvendes i farmaceutisk produktion?
What are different types of water used in pharmaceutical production?
Der anvendes adskillige forskellige typer vand i farmaceutisk produktion. I alle disse typer bør TOC af vand og biobyrde i vandsystemet overvågens korrekt. De anvendes hver især på forskellige stadier i processen og har forskellige specifikationer, hvad angår renhed. Renset vand (PW) er vand, der er blevet renset til et lavt niveau af urenheder. Vand til indsprøjtning (WFI) er vand, der anvendes som hjælpestof i produktionen af parenterale lægemidler. Ultrarent vand (UPW) er vand, der er blevet renset til et ekstremt lavt niveau af urenheder, som skal efterleve meget strenge specifikationer.
There are several different types of water that are used in pharmaceutical production. In each of these, the TOC of water and bioburden in the water system should be properly monitored. Each is used at different steps in the process and has different specifications for purity. Purified Water (PW) is water that has been processed to remove impurities to low levels. Water for Injection (WFI) is water used as an excipient in the production of parenteral medications. Ultrapure Water (UPW) is water that has been purified to extremely low levels of impurities that must meet very strict specifications.