title: Effects of Dietary Coconut Oil on the Biochemical and Anthropometric Profiles of Women Presenting Abdominal Obesity Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women Plasma lipid and lipoprotein response of humans to beef fat, coconut oil and safflower oil. Medium-chain fatty acids: evidence for incorporation into chylomicron triglycerides in humans. Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. The effect of daily consumption of coconut fat and soya-bean fat on plasma lipids and lipoproteins of young normolipidaemic men. Virgin olive oil, palm olein and coconut oil diets do not raise cell adhesion molecules and thrombogenicity indices in healthy Malaysian adults Low linolenate and commercial soybean oils diminish serum HDL cholesterol in young free-living adult females. The Impact of Virgin Coconut Oil and High-Oleic Safflower Oil on Body Composition, Lipids, and Inflammatory Markers in Postmenopausal Women. A randomized study of coconut oil versus sunflower oil on cardiovascular risk factors in patients with stable coronary heart disease The effect of supplemental dietary fat on plasma cholesterol levels in lovastatin-treated hypercholesterolemic patients. Diets high in palmitic acid (16:0), lauric and myristic acids (12:0 + 14:0), or oleic acid (18:1) do not alter postprandial or fasting plasma homocysteine and inflammatory markers in healthy Malaysian adults. Sea buckthorn berry oil inhibits platelet aggregation. Supplementation-Dependent Effects of Vegetable Oils with Varying Fatty Acid Compositions on Anthropometric and Biochemical Parameters in Obese Women Corn Oil Lowers Plasma Cholesterol Compared with Coconut Oil in Adults with Above-Desirable Levels of Cholesterol in a Randomized Crossover Trial
abstract: The effects of dietary supplementation with coconut oil on the biochemical and anthropometric profiles  of women presenting waist circumferences ( WC ) > 88 cm ( abdominal obesity ) were investigated . The r and omised , double-blind , clinical trial involved 40 women aged 20–40 years . Groups received daily dietary supplements comprising 30 mL of either soy bean oil ( group S ; n = 20 ) or coconut oil ( group C ; n = 20 ) over a 12-week period , during which all subjects were instructed to follow a balanced hypocaloric diet and to walk for 50 min per day . Data were collected 1 week before ( T1 ) and 1 week after ( T2 ) dietary intervention . Energy intake and amount of carbohydrate ingested by both groups diminished over the trial , whereas the consumption of protein and fibre increased and lipid ingestion remained unchanged . At T1 there were no differences in biochemical or anthropometric characteristics between the groups , whereas at T2 group C presented a higher level of HDL ( 48.7 ± 2.4 vs. 45.00 ± 5.6 ; P = 0.01 ) and a lower LDL : HDL ratio ( 2.41 ± 0.8 vs. 3.1 ± 0.8 ; P = 0.04 ) . Reductions in BMI were observed in both groups at T2 ( P < 0.05 ) , but only group C exhibited a reduction in WC ( P = 0.005 ) . Group S presented an increase ( P < 0.05 ) in total cholesterol , LDL and LDL : HDL ratio , whilst HDL diminished ( P = 0.03 ) . Such alterations were not observed in group C. It appears that dietetic supplementation with coconut oil does not cause dyslipidemia and seems to promote a reduction in abdominal obesity Introduction High dietary saturated fat intake is associated with higher blood concentrations of low-density lipoprotein cholesterol ( LDL-C ) , an established risk factor for coronary heart disease . However , there is increasing interest in whether various dietary oils or fats with different fatty acid profiles such as extra virgin coconut oil may have different metabolic effects but trials have reported inconsistent results . We aim ed to compare changes in blood lipid profile , weight , fat distribution and metabolic markers after four weeks consumption of 50 g daily of one of three different dietary fats , extra virgin coconut oil , butter or extra virgin olive oil , in healthy men and women in the general population . Design R and omised clinical trial conducted over June and July 2017 . Setting General community in Cambridgeshire , UK . Participants Volunteer adults were recruited by the British Broadcasting Corporation through their websites . Eligibility criteria were men and women aged 50–75 years , with no known history of cancer , cardiovascular disease or diabetes , not on lipid lowering medication , no contraindications to a high-fat diet and willingness to be r and omised to consume one of the three dietary fats for 4 weeks . Of 160 individuals initially expressing an interest and assessed for eligibility , 96 were r and omised to one of three interventions ; 2 individuals subsequently withdrew and 94 men and women attended a baseline assessment . Their mean age was 60 years , 67 % were women and 98 % were European Caucasian . Of these , 91 men and women attended a follow-up assessment 4 weeks later . Intervention Participants were r and omised to extra virgin coconut oil , extra virgin olive oil or unsalted butter and asked to consume 50 g daily of one of these fats for 4 weeks , which they could incorporate into their usual diet or consume as a supplement . Main outcomes and measures The primary outcome was change in serum LDL-C ; secondary outcomes were change in total and high-density lipoprotein cholesterol ( TC and HDL-C ) , TC/HDL-C ratio and non-HDL-C ; change in weight , body mass index ( BMI ) , waist circumference , per cent body fat , systolic and diastolic blood pressure , fasting plasma glucose and C reactive protein . Results LDL-C concentrations were significantly increased on butter compared with coconut oil ( + 0.42 , 95 % CI 0.19 to 0.65 mmol/L , P<0.0001 ) and with olive oil ( + 0.38 , 95 % CI 0.16 to 0.60 mmol/L , P<0.0001 ) , with no differences in change of LDL-C in coconut oil compared with olive oil ( −0.04 , 95 % CI −0.27 to 0.19 mmol/L , P=0.74 ) . Coconut oil significantly increased HDL-C compared with butter ( + 0.18 , 95 % CI 0.06 to 0.30 mmol/L ) or olive oil ( + 0.16 , 95 % CI 0.03 to 0.28 mmol/L ) . Butter significantly increased TC/HDL-C ratio and non-HDL-C compared with coconut oil but coconut oil did not significantly differ from olive oil  for TC/HDL-C and non-HDL-C. There were no significant differences in changes in weight , BMI , central adiposity , fasting blood glucose , systolic or diastolic blood pressure among any of the three intervention groups . Conclusions and relevance Two different dietary fats ( butter and coconut oil ) which are predominantly saturated fats , appear to have different effects on blood lipids compared with olive oil , a predominantly monounsaturated fat with coconut oil more comparable to olive oil with respect to LDL-C. The effects of different dietary fats on lipid profiles , metabolic markers and health outcomes may vary not just according to the general classification of their main component fatty acids as saturated or unsaturated but possibly according to different profiles in individual fatty acids , processing methods as well as the foods in which they are consumed or dietary patterns . These findings do not alter current dietary recommendations to reduce saturated fat intake in general but highlight the need for further elucidation of the more nuanced relationships between different dietary fats and health . Trial registration number NCT03105947 ; Results This study 's purpose was to evaluate the fasting human plasma lipid and lipoprotein responses to dietary beef fat ( BF ) by comparison with coconut oil ( CO ) and safflower oil ( SO ) , fats customarily classified as saturated and polyunsaturated .  Nineteen free-living normolipidemic men aged 25.6 + /- 3.5 yr consumed central ly-prepared lunches and dinners of common foods having 35 % fat calories , 60 % of which was the test fat . The test fats were isocalorically substituted , and each fed for five weeks in r and om sequences with intervening five weeks of habitual diets .  Plasma total cholesterol ( TC ) , high-density lipoprotein cholesterol ( HDL-C ) , and low-density lipoprotein cholesterol ( LDL-C ) concentrations among individuals follows the same relative rank regardless of diet . Triglycerides ( TG ) concentrations among individuals also maintain their relative rank regardless of diet but in a different order from that of the cholesterols . Plasma TC , HDL-C , and LDL-C responses to BF were significantly lower and TG higher than to CO . As compared to SO , BF produced equivalent levels of TG , HDL-C , and LDL-C and marginally higher TC . Thus , the customary consideration of BF as " saturated " and grouping it with CO appears unwarranted The purpose of this study was to evaluate the fatty acid composition of chylomicron triglycerides isolated from subjects fed liquid-formula diets containing 40 % of total energy as medium- ( C8:0 and C10:0 ) or long-chain ( C16-C18 ) triglycerides ( MCT , LCT )  for 6 d. Medium-chain fatty acids ( MCFA ) comprised 8 % of total chylomicron triglyceride fatty acids after the first MCT meal . After 6 d of continued MCT feeding , chylomicron triglyceride MCFA content increased to 13 % . When subjects were fed the LCT ( soybean oil ) diet , C16:0 , C18:1 , and C18:2 comprised nearly 90 % of the chylomicron triglyceride fatty acids . The mass of triglyceride transported in chylomicrons isolated from subjects fed the MCT diet was approximately 20 % of that found when subjects consumed the LCT diet . We conclude that although total triglyceride production during MCT ingestion is low , the chylomicron triglycerides that are synthesized contain significant amounts of MCFA The effects of lauric acid ( C12:0 ) on plasma lipids and lipoproteins were compared with the effects of palmitic acid ( C16:0 ) and oleic acid ( C18:1 ) in a metabolic-diet study of 14 men by using liquid-formula diets fed for 3 wk each in r and om order . Lauric acid was supplied in a synthetic high-lauric oil , palmitic acid was provided by palm oil and oleic acid in oleic-rich sunflower seed oil . The high-lauric oil result ed in higher concentrations of plasma total cholesterol ( 4.94 + /- 0.75 mmol/L [ mean + /- SE ] ) and LDL cholesterol ( 3.70 + /- 0.57 mmol/L ) when compared with high-oleic sunflower oil ( 4.44 + /- 0.54 and 3.31 + /- 0.44 mmol/L , respectively ) , but did not raise total and LDL cholesterol concentrations as much as did palm oil ( 5.17 + /- 0.65 and 3.93 + /- 0.51 mmol/L , respectively ) . No differences were noted in plasma triglycerides or HDL cholesterol .  Lauric acid raises total and LDL cholesterol concentrations compared with oleic acid , but is not as potent for increasing cholesterol concentrations as is palmitic acid The present paper reports the influence on plasma lipids of isoenergetic diets containing 30 % of energy as fat , with a polyunsaturated : saturated fat ratio of 4.00 or 0.25 , consumed for 8 weeks by twenty-five young normolipidaemic males . Approximately 70 % of the fat energy was provided by the test fats : soya-bean fat and coconut fat . During the soya-bean-fat-eating period the total plasma cholesterol level fell significantly compared with baseline values ( P less than 0.001 ) and during the coconut-fat-eating phase total plasma cholesterol level increased significantly compared with the soya-bean-eating period ( P less than 0.001 ) . On the soya-bean-fat diet , high-density-lipoprotein (HDL)-cholesterol decreased by 15 % ( range 6 - 35 % ) and plasma triacylglycerols decreased by 25 % ( range 13 - 37 % ) . Results of the present study show that even when the proportion of total fat in the diet is low , a high intake of linoleic acid lowers both total plasma cholesterol and HDL-cholesterol , while a high intake of saturated fat elevates both these lipid fractions . Application of regression formulas to the present findings indicates that short-chain saturated fatty acids have a neutral effect on serum cholesterol Background / objectives : Effects of high-protein diets that are rich in saturated fats on cell adhesion molecules , thrombogenicity and other nonlipid markers of atherosclerosis in humans have not been firmly established . We aim to investigate the effects of high-protein Malaysian diets prepared separately with virgin olive oil ( OO ) , palm olein ( PO ) and coconut oil ( CO ) on cell adhesion molecules , lipid inflammatory mediators and thromobogenicity indices in healthy adults . Methods : A r and omized cross-over intervention with three dietary sequences , using virgin OO , PO and CO as test fats , was carried out for 5 weeks on each group consisting of 45 men and women . These test fats were incorporated separately at two-thirds of 30 % fat calories into high-protein Malaysian diets . Results : For fasting and nonfasting blood sample s , no significant differences were observed on the effects of the three test-fat diets on thrombaxane B2 ( TXB2 ) , TXB2/PGF1α ratios and soluble intracellular and vascular cell adhesion molecules . The OO diet induced significantly lower ( P<0.05 ) plasma leukotriene B4 ( LTB4 ) compared with the other two test diets , whereas PGF1α concentrations were significantly higher ( P<0.05 ) at the end of the PO diet compared with the OO diet . Conclusion : Diets rich in saturated fatty acids from either PO or CO and high in monounsaturated oleic acid from virgin OO do not alter the thrombogenicity indices — cellular adhesion molecules , thromboxane B2 ( TXB2 ) and TXB2/prostacyclin ( PGF1α ) ratios . However , the OO diet lowered plasma proinflammatory LTB4 , whereas the PO diet raised the antiaggregatory plasma PGF1α in healthy Malaysian adults . This trial was registered at clinical trials.gov as NCT 00941837 OBJECTIVE A mutant soybean line ( A16 ) low in linolenic acid content ( 2 % of oil by weight ) was developed to increase oil oxidative stability . It was unknown whether serum lipid and lipoprotein concentrations in humans would be affected should A16 soybean oil ( A16 oil ) replace commercial soybean oil in diets . This study was conducted to examine the hypothesis that in free-living normolipidemic women , the consumption of A16 oil at approximately 10 % of energy intake ( en% ) would not affect serum lipids and lipoproteins differently than would the consumption of the same amount of a commercial soybean oil with 7 % of linolenic acid content . DESIGN Fifteen free-living female college students consumed the soybean oil daily with regular meals for 9 weeks in different orders , with each test oil being eaten for 3 weeks . During the study , 13 en% was provided by each test oil and a total of 35 en% was from dietary fat . Serum concentrations of total cholesterol , high-density lipoprotein cholesterol ( HDL cholesterol ) , low-density lipoprotein cholesterol ( LDL cholesterol ) and triacylglycerides ( TAG ) were measured . Serum total fatty acid patterns were analyzed as well . RESULTS Each of the three test oils decreased serum total cholesterol , LDL cholesterol and TAG concentrations from the baseline values . The feeding of A16 and commercial soybean oils decreased serum HDL cholesterol significantly compared with coconut oil ( p < 0.05 ) . Dietary inclusion of coconut oil increased serum myristic acid significantly more than did either soybean oil ( p < 0.01 ) . Serum arachidonic acid concentrations were significantly greater with A16 consumption than with commercial soybean oil consumption ( p < 0.001 ) . CONCLUSION A16 and commercial soybean oils both diminished serum HDL cholesterol . Although the fatty acid composition differed between the two soybean oils , A16 oil and commercial oil had similar effects on serum concentrations of lipoproteins and lipids . With increased oxidative stability , A16 oil is a good alternative to commercial soybean oil This r and omized crossover study compared the impact of virgin coconut oil ( VCO ) to safflower oil ( SO ) on body composition and cardiovascular risk factors . Twelve postmenopausal women ( 58.8 ± 3.7 year ) consumed 30 mL VCO or SO for 28 days , with a 28-day washout . Anthropometrics included body weight and hip and waist circumference . Fat percent for total body , and roid and gynoid , fat mass , and lean mass were measured using dual-energy X-ray absorptiometry . Women maintained their typical diet recording 28 days of food records during the study . Results were analyzed with SPSS v24 with significance at P ≤ .05 . Comparisons are reported as paired t-test since no intervention sequence effect was observed . VCO  significantly raised total cholesterol , TC ( + 18.2 ± 22.8 mg/dL ) , low-density lipoprotein ( + 13.5 ± 16.0 mg/dL ) , and high-density lipoprotein , HDL ( + 6.6 ± 7.5 mg/dL ) . SO did not significantly change lipid values . TC and HDL were significantly different between test oils . The TC/HDL ratio change showed a neutral effect of both VCO and SO . One person had adverse reactions to VCO and increased inflammation .  VCO  decreased IL-1β for each person who had a detected sample . The impact of VCO and SO on other cytokines varied on an individual basis . This was the first study evaluating the impact of VCO on body composition in Caucasian postmenopausal women living in the United States . Results are suggestive that individuals wishing to use coconut oil in their diets can do so safely , but more studies need to be conducted with larger sample sizes , diverse population s , and more specific clinical markers such as particle size Background and rationale Coronary artery disease ( CAD ) and its pathological atherosclerotic process are closely related to lipids . Lipids levels are in turn influenced by dietary oils and fats . Saturated fatty acids increase the risk for atherosclerosis by increasing the cholesterol level . This study was conducted to investigate the impact of cooking oil media ( coconut oil and sunflower oil ) on lipid profile , antioxidant mechanism , and endothelial function in patients with established CAD . Design and methods In a single center r and omized study in India , patients with stable CAD on st and ard medical care were assigned to receive coconut oil ( Group I ) or sunflower oil ( Group II ) as cooking media for 2 years . Anthropometric measurements , serum , lipids , Lipoprotein a , apo B/A-1 ratio , antioxidants , flow-mediated vasodilation , and cardiovascular events were assessed at 3 months , 6 months , 1 year , and 2 years . Results Hundred patients in each arm completed 2 years with 98 % follow-up . There was no statistically significant difference in the anthropometric , biochemical , vascular function , and in cardiovascular events after 2 years . Conclusion Coconut oil even though rich in saturated fatty acids in comparison to sunflower oil when used as cooking oil media over a period of 2 years did not change the lipid-related cardiovascular risk factors and events in those receiving st and ard medical care STUDY OBJECTIVE A validation study was conducted first to test assumptions about the effect of saturated and unsaturated dietary fat supplements . The second study was conducted to determine the effect on blood cholesterol levels of saturated and unsaturated fat supplements in patients who followed a low-fat diet and were administered lovastatin . DESIGN R and omized , crossover design , with three periods in the first study and four in the second study , each lasting 6 weeks . SETTING Cholesterol Research Center . PATIENTS The first study evaluated adults with total cholesterol levels between 200 and 280 mg/dl ( 5.172 and 7.241 mmol/L ) . The second study included adults with low-density lipoprotein ( LDL ) cholesterol levels above 160 mg/dl ( 4.138 mmol/L ) . INTERVENTIONS Fat supplements with either coconut or canola oil were delivered to patients in oatmeal-raisin cookies . MEASUREMENTS AND MAIN RESULTS In the validation study , patients ' mean prer and omization total cholesterol level of 222 mg/dl was reduced to 213 mg/dl with canola oil and increased to 233 mg/dl with coconut oil cookies ( p = 0.0038 ) . In the second study the mean prer and omization total cholesterol level of 214 mg/dl was decreased to 199 mg/dl with canola oil and to 208 mg/dl with coconut oil cookies ( p = 0.2342 ) . The LDL cholesterol levels changed in a similar fashion in both studies . CONCLUSIONS Changes in total and LDL cholesterol levels in the validation study were expected based on established effects of saturated and unsaturated fatty acids , but changes in these levels in lovastatin-cookie study were not expected . They could have occurred because lovastatin reversed the effect of saturated fats and enhanced the effect of unsaturated fats . Alternatively , they may have been due to enhanced bioavailability of lovastatin when administered with a high-fat diet . These findings must be confirmed BACKGROUND Dietary fat type is known to modulate the plasma lipid profile , but its effects on plasma homocysteine and inflammatory markers are unclear . OBJECTIVE We investigated the effects of high-protein Malaysian diets prepared with palm olein , coconut oil ( CO ) , or virgin olive oil on plasma homocysteine and selected markers of inflammation and cardiovascular disease ( CVD ) in healthy adults . DESIGN A r and omized-crossover intervention with 3 dietary sequences of 5 wk each was conducted in 45 healthy subjects . The 3 test fats , namely palmitic acid (16:0)-rich palm olein ( PO ) , lauric and myristic acid ( 12:0 + 14:0)-rich CO , and oleic acid (18:1)-rich virgin olive oil ( OO ) , were incorporated at two-thirds of 30 % fat calories into high-protein Malaysian diets . RESULTS No significant differences were observed in the effects of the 3 diets on plasma total homocysteine ( tHcy ) and the inflammatory markers TNF-α , IL-1β , IL-6 , and IL-8 , high-sensitivity C-reactive protein , and interferon-γ . Diets prepared with PO and OO had comparable nonhypercholesterolemic effects ; the postpr and ial total cholesterol for both diets and all fasting lipid indexes for the OO diet were significantly lower ( P < 0.05 ) than for the CO diet . Unlike the PO and OO diets , the CO diet was shown to decrease postpr and ial lipoprotein(a ) . CONCLUSION Diets that were rich in saturated fatty acids prepared with either PO or CO , and an OO diet that was high in oleic acid , did not alter postpr and ial or fasting plasma concentrations of tHcy and selected inflammatory markers . This trial was registered at clinical trials.gov as NCT00941837 A small-scale preliminary cross-over study was conducted to investigate the effects of supercritical CO(2)-extracted sea buckthorn berry oil ( SBO ) on some  risk factors  of  cardiovascular disease .  Special features of the oil are high proportions of palmitic ( 16:0 ) , oleic ( 18:1n-9 ) , palmitoleic ( 16:1n-7 ) , linoleic ( 18:2n-6 ) , and alpha-linolenic ( 18:3n-3 ) acids as well as vitamin E , carotenoids , and sterols . Twelve healthy normolipidemic men were recruited and each volunteer consumed SBO and fractionated coconut oil ( control ) 5 g per day for a period of 4 weeks in a r and om order ( wash-out 4 - 8 weeks ) . Phospholipid fatty acids , plasma lipids , and glucose were unaffected by SBO supplementation . Instead , a clear decrease in the rate of adenosine-5'-diphosphate-induced platelet aggregation and maximum aggregation were found . This suggested the beneficial effects of SBO on blood clotting , but further studies on the dose-response effects are needed to assess the practical use of SBO supplements Fatty acid ( FA ) composition is a determinant of the physiological effects of dietary oils . This study investigated the effects of vegetable oil supplementation with different FA compositions on anthropometric and biochemical parameters in obese women on a hypocaloric diet with lifestyle modifications . Seventy-five women ( body mass index , BMI , 30–39.9kg/m2 ) were r and omized based on 8-week oil supplementation into four experimental groups : the coconut oil group ( CoG , n = 18 ) , the safflower oil group ( SafG , n = 19 ) , the chia oil group ( ChG , n = 19 ) , and the soybean oil placebo group ( PG , n = 19 ) . Pre- and post-supplementation weight , anthropometric parameters , and body fat ( % BF ) , and lean mass percentages ( % LM ) were evaluated , along with biochemical parameters related to lipid and glycidemic profiles . In the anthropometric evaluation , the CoG showed greater weight loss ( Δ% = −8.54 ± 2.38 ) , and reduced BMI ( absolute variation , Δabs = −2.86 ± 0.79 ) , waist circumference ( Δabs = −6.61 ± 0.85 ) , waist-to-height ratio ( Δabs = −0.041 ± 0.006 ) , conicity index ( Δabs = −0.03 ± 0.016 ) , and % BF ( Δabs = −2.78 ± 0.46 ) , but increased % LM ( Δabs = 2.61 ± 1.40 ) ( p < 0.001 ) . Moreover , the CoG showed a higher reduction in biochemical parameters of glycemia ( Δabs = −24.71 ± 8.13 ) and glycated hemoglobin ( Δabs = −0.86 ± 0.28 ) ( p < 0.001 ) . The ChG showed a higher reduction in cholesterol ( Δabs = −45.36 ± 0.94 ) , low-density lipoprotein cholesterol ( LDLc ; Δabs = −42.53 ± 22.65 ) , and triglycerides ( Δabs = −49.74 ± 26.3 ) , but an increase in high-density lipoprotein cholesterol ( HDLc ; abs = 3.73 ± 1.24 , p = 0.007 ) . Coconut oil had a more pronounced effect on abdominal adiposity and glycidic profile , whereas chia oil had a higher effect on improving the lipid profile . Indeed , supplementation with different fatty acid compositions result ed in specific responses ABSTRACT Background Few trials have examined the effects of coconut oil consumption in comparison with polyunsaturated fatty acid – rich oils such as corn oil . Objective This trial assessed the effects of consuming foods made with corn oil compared with coconut oil on lipids , glucose homeostasis , and inflammation . Methods This was a preliminary r and omized crossover study of men ( n = 12 ) and women ( n = 13 ) with a mean age of 45.2 y , mean body mass index ( in kg/m2 ) of 27.7 , fasting LDL cholesterol ≥115 mg/dL and < 190 mg/dL , and triglycerides ( TGs ) ≤375 mg/dL. Subjects consumed muffins and rolls providing 4 tablespoons ( ∼54 g ) per day of corn oil or coconut oil as part of their habitual diets for 4 wk , with a 3-wk washout between conditions . Fasting plasma lipids and high-sensitivity C-reactive protein ( hs-CRP ) and glucose metabolism were assessed via an intravenous glucose tolerance test at baseline and 15 and 29 d of treatment . Responses were compared between treatments by ANCOVA . Results Median baseline concentrations of LDL cholesterol , non-HDL cholesterol , total cholesterol ( total-C ) , HDL cholesterol , total-C : HDL cholesterol , and TGs were 123 , 144 , 188 , 46.0 , 4.21 , and 92.5 mg/dL , respectively . Changes from baseline for corn oil and coconut oil conditions , respectively , were : LDL cholesterol ( primary outcome ; −2.7 % compared with + 4.6 % ) , non-HDL cholesterol ( −3.0 % compared with + 5.8 % ) , total-C ( −0.5 % compared with + 7.1 % ) , HDL cholesterol ( + 5.4 % compared with + 6.5 % ) , total-C : HDL cholesterol ( −4.3 % compared with −3.3 % ) , and TGs ( −2.1 % compared with + 6.0 % ) . Non-HDL cholesterol responses were significantly different between corn and coconut oil conditions ( P = 0.034 ) ; differences between conditions in total-C and LDL cholesterol approached significance ( both P = 0.06 ) . Responses for hs-CRP and carbohydrate homeostasis parameters did not differ significantly between diet conditions . Conclusions When incorporated into the habitual diet , consumption of foods providing ∼54 g of corn oil/d produced a more favorable plasma lipid profile than did coconut oil in adults with elevated cholesterol . This trial was registered at clinical trials.gov as NCT03202654
target: Coconut oil consumption did not significantly affect markers of glycemia , inflammation , and adiposity as compared with nontropical vegetable oils .
  Conclusions : Coconut oil consumption results in significantly higher LDL-cholesterol than nontropical vegetable oils .
background: Background : Coconut oil is high in saturated fat and may , therefore , raise serum cholesterol concentrations , but beneficial effects on other cardiovascular risk factors have also been suggested .
  Therefore , we conducted a systematic review of the effect of coconut oil consumption on blood lipids and other cardiovascular risk factors compared with other cooking oils using data from clinical trials .