This is due in the main to sedimentation, pollution and over-fishing. These practices have now spread to the high seas, where, if left unchecked, are likely to result in the commercial extinction of a significant number of fish species, including many that are crucial for the sustenance of millions of people. The European Commission estimates that for stocks with sufficient data for assessment, 78.5 per cent are exploited unsustainably with 43 per cent outside of safe biological limits. A review of 48 stocks managed by regional fisheries management organisations (RFMOs) found that 32 (67 per cent) were overexploited or collapsed.