Without working with men and boys, discrimination, violence and inequality will continue. Sufficient opportunities and knowledge must be afforded for how young people, particularly boys and young men, can challenge gender norms, stereotypes and harmful practices. Furthermore, reaching adolescent boys through age-appropriate comprehensive sexuality education, which allows them to reflect and question predominant norms around masculinity and femininity, is a critical way to better ensure future generations of gender-equitable men. Communicating positive messages—that change is possible and that boys can positively influence not only their own lives but also that of girls—can increase boys’ participation and responsiveness.