Italy has launched in 2000 the National Programme on Continuing Education in Medicine (NPCEM), which requires health care professionals to obtain 50 CME credits per year. The system is not link to re-certification. The safety of pharmaceuticals is further ensured through a postmarketing surveillance system which monitors safety information and adverse reaction for all authorised drugs through the National Network of Pharmacovigilance (Refe Nazionale di Farmacovigilanza).