Universiti Sains Malaysia has a structure dedicated to start-up support with facilities for on-campus business incubation. The involvement of key actors, such as the school of computer science in the design and organisation of incubation facilities suggests that the university leadership collaborates, co-ordinates and integrates faculty-internal entrepreneurship support in the US M’s support infrastructure and thus ensure cross-faculty collaboration. Two key issues for further development call for closer links between entrepreneurship education efforts and start-up support, and closer co-operation and referral between internal and external business start-up support organisations.