The chapter makes a call for greater innovation in sub-national government and governance to support the city as it moves forward in realising its aims. Antofagasta has followed a similar pattern, yet the quality of life in the municipality does not appear to be commensurate with its economic and socio-economic potential or its place-based endowments. Between 2002 and 2013, the municipality of Antofagasta improved its relative ranking in a Quality of Life Index developed by Chile’s Universidad Catolica.