Question: With regard to the alkaloids derived from ergoline: 
 Options:  <1> They can be obtained by fermentation of pure Claviceps purpurea cultures and derived from phenylalanine and isoprene obtained by the mevalonic acid route (MVA). <2> They can be obtained by fermentation of pure cultures of Claviceps purpurea and derived from tyrosine and isoprene obtained by the DOXP route. <3> They can be obtained by fermentation of pure cultures of Claviceps purpurea and derived from tryptophan and isoprene obtained by the route of mevalonic acid (MVA). <4> They can be obtained by rye infection with Claviceps purpurea spores and derived from tryptophan and isoprene obtained by the DOXP route. <5> They can be obtained by wheat infection with Claviceps purpurea spores and derived from tyrosine and isoprene obtained by the mevalonic acid (MVA) route.
3