Question: A 68-year-old woman diagnosed with pulmonary tuberculosis. Treatment with Isoniacid, Rifampicin and Ethambutol was started. At 12 days after the start of treatment, he consulted for fever of 38ºC, skin rash, lymphadenopathy, arthralgia, lumbar pain, oliguria and eosinophilia with acute deterioration of renal function. The urine test revealed hematuria, leukocyturia with eosinophiluria in Wright's stain and non-nephrotic proteinuria (1.2 grams daily). With these clinical data the most likely diagnosis is: 
 Options:  <1> Acute tubular necrosis due to drug nephrotoxicity. <2> Acute tubular necrosis of ischemic etiology. <3> Ateroembolic disease. <4> Thrombotic occlusion of the main renal artery. <5> Acute tubulointerstitial nephritis.
5