Question: The use of the standard addition method in the calibration of an instrumental analysis method is recommended: 
 Options:  <1> Whenever possible <2> When analyzing complex samples in which important matrix effects are likely to occur and you want to minimize them. <3> When you want to determine very high concentrations of analyte. <4> When you want to use a dilution factor. <5> In automated acid-base volumetries.
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