Question: The independent parameter of the dissolution model, the solution efficiency, has two limitations. One of them is that the last experimental point has an arbitrary nature. What is the other limitation ?: 
 Options:  <1> At least 50% of the dose must be dissolved. <2> At least 60% of the dose must be dissolved. <3> At least 75% of the dose must be dissolved. <4> At least 80% of the dose must be dissolved. <5> At least 90% of the dose must be dissolved.
5