Question: Jaundice (yellowing of the skin and mucous membranes due to increased levels of bilirubin) may be of cholestatic origin (pathway obstruction) or hepatocellular damage. Indicate the correct answer: 
 Options:  <1> In cholestatic jaundice we observed: persistent alanine aminotransferase (ALT) increase without elevation of gamma glutamyltransferase (GGT). <2> In hepatocellular jaundice there is a slight increase in GGT (<5 times the upper limit of reference) and a large increase in ALT (> 10 times the upper limit of reference). <3> In cholestatic jaundice, a decrease in direct bilirubin and prothrombin time is observed. <4> In hepatocellular jaundice, a decrease in alkaline phosphatase and activated partial thromboplastin time is observed. <5> In both jaundices we can observe a clear decrease in aspartate aminotransferase (AST).
2