Question: We want to study if Vitamin D can increase the incidence of breast cancer. In our area we have a population registry of cancer. To achieve our goal, all women diagnosed with breast cancer are selected from the register we have and each case pairs with two controls. What study design has been chosen? 
 Options:  <1> Prospective cohort study. <2> Cases and controls study. <3> Case-control study nested. <4> Retrospective cohort study. <5> Ecological study
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