Question: A colonoscopy of colorectal cancer screening is performed on a patient with ulcerative colitis with involvement up to the transverse colon. Colonoscopy shows no signs of inflammatory activity. Multiple biopsies were performed every 10 cm. The biopsies were reviewed by 2 expert pathologists demonstrating a focus of high grade dysplasia in one of the biopsies performed in the sigmoid colon. What would you indicate next? 
 Options:  <1> Repeat the colonoscopy to confirm the diagnosis. <2> Intensive surveillance with colonoscopy every 3 to 6 months. <3> Repeat the examination and perform a chromoendoscopy to identify the lesion and perform an endoscopic mucosectomy. <4> Total proctocolectomy. <5> Treatment with mesalazine at doses of 2-3 grams per day and repeat the scan at 3 to 6 months.
4