Background Paragraph: Allergy symptoms can range from mild to severe. Mild symptoms might include itchy eyes, sneezing, and a runny nose. Severe symptoms can cause difficulty breathing, which may be life threatening. Keep in mind that it is the immune system and not the allergen that causes the allergy symptoms. Allergy symptoms can be treated with medications such as antihistamines. Severe allergic reactions may require an injection of the hormone epinephrine. These treatments lessen or counter the immune system’s response. 
Story: Two sisters both had allergies. Ann had mild allergies, while Jo had to be very careful because she experienced severe allergic reactions before.
Which sister didn't experience sneezing? Which sister didn't get itchy eyes? Which sister didn't have a runny nose? Which sister didn't have difficulty breathing because of the allergic reactions? Which sister didn't require an injection of the hormone epinephrine? Which sister had difficulty breathing because of the allergic reactions? Which sister might have had a runny nose? Which sister might have had itchy eyes? Which sister might have had sneezing? Which sister might have required an injection of the hormone epinephrine?