Question: In the path that leads in the liver to acetoacetate biosynthesis from acetyl CoA, which of the following substances is the immediate precursor of acetoacetate? 
 Options:  <1> 3-Hydroxybutyrate <2> Acetoacetyl CoA. <3> 3-Hydroxybutyrate CoA. <4> Mevalonic acid. <5> 3-Hydroxy-3-methylglutaryl. CoA.
5