Strain elastosonography frame in a case of right parietal GBM (case no. 3). Elastosonography gives information about the stiffness of the tissue, and it is revealed through a chromatic scale. Red spots are representative of softer zones (necrotic areas); blue spots are representative of harder zones (brain–tumor interface and brain parenchyma). The core of the lesions appears to be softer than surrounding normal brain parenchyma. White arrow: GBM. Yellow arrow: surrounding normal brain parenchyma.