Grade IC. A 71-year-old woman. A geographic lytic bone tumor in the proximal left humerus is observed. The tumor is geographic in nature and has a ragged and poorly defined margin (solid arrow). Total penetration of cortex is evident (dashed arrow) and results in assignment of Lodwick growth grade IC. The evaluation regarding a sclerotic rim and an expanded shell is not necessary to assign this growth grade. The tumor proved to be diffuse large B-cell non-Hodgkin Lymphoma