Caucasian woman (78 years old) suffering from bilateral unexplained panuveitis. Whole body 18F-FDG PET (maximum intensity projection anterior view) demonstrated significant bilateral hilar, mediastinal and right supraclavicular lymph nodes uptakes (black arrows) while there was no node enlargement on chest CT. A subsequent supraclavicular node dissection revealed noncaseating epithelioid granulomas consistent with sarcoidosis. Special staining and culture for mycobacteria were negative.