MR-lymphography at 3 Tesla using USPIO. Patient with prostate cancer and lymphatic metastases. Left image shows the morphological T1 weighted coronal sequence with two small lymph nodes near to the left common iliac artery. Right image shows the corresponding T2* weighted coronal image 24 h after the intravenous administration of an USPIO agent (ferumoxtran-10). The lymph node marked by the green circle shows an USPIO uptake and therefore a signal loss in the T2* image suggesting normal lymphatic tissue. The lymph node marked by the red circle does not show any USPIO uptake and therefore shows a bright signal on the T2* image. This lymph node is highly suspect for metastasis.