Region of interest (ROI) placement in the raw T2 map in accordance with the fluid-attended inversion recovery (FLAIR) sequences. The slice with the largest diameter of peritumoral T2-weighted/FLAIR hyperintensity was chosen, the anatomical centre of the tumour was delineated. Another ROI was placed in the healthy- appearing white matter of the contralateral lobe using an image processing program to ensure reliability of the measurements. The spatial T2 value distribution across the tumour radius was measured at four different locations from the tumour centre to the outer infiltration zone by the placement of three further ROIs.