
endomorphine-2

endomorphine-2 (emm-2) anedi oka antarjanita opioid peptide mariyu rendu endomorphinelalo okati. idhi amaino assid sequence tyre-proo-phay-enhetch2 nuu kaligi undhi. idhi adhika anubandham, micro-opioid receptor yokka atyanta empikaina agonist, mariyu endomorphine-1 (emm-1) thoo paatu, eee receptor yokka vaastava endogenous ligand (antey, endorphines kakunda) gaa pratipaadinchabadindi. emm-1 maadirigaane, emm-2 jantuvulalo analgesianu utpatti chestundi, conny emm-1 medadulo ekkuvagaa unnappatikee, emm-2 vennupaamulo ekkuvagaa untundi. adanamgaa, emm-2 yokka charya emm-1 nundi kontha bhinnamgaa untundi, endukante emm-2 adanamgaa vennupamu mariyu medadulo dynorphine eah mariyu [mett] encaphaline vidudalanu oka teliyani yantraangam dwara prerepistundi, idhi varusaga κ-mariyu δ-opioid grahakalanu sakriyam chestundi, mariyu emm-2 yokka analgesic prabhavalalo kontha bhaagam eee charyapai aadharapadi untundi. antekakunda, emm-1 niyata sthala praadhaanyatanu utpatti chestundi, idhi aushadha bahumati yokka kolata, emm-2 niyata sthala "virakti" nii utpatti chestundi, idhi dynorphine-eah-aadhaarita prabhavam. emm-1 maadirigaane, emm-2 kosam janyu encoding inca gurtinchabadaledu.