
vidyut impedence myography

electrical impedence myography ledhaa eim anedi kandaraala aarogyaanni anchanaa vaeyadaaniki oka naan-invasive technic, idhi vyaktigata kandaraalu ledhaa kandaraala samuuhaala vidyut impedence lakshanaala kolatapai aadharapadi untundi. eee saanketikata naadii kandaraala vyaadhulanu vaati nirdhaarana kosam mariyu vaati purogati yokka konasagutunna anchanaa kosam ledhaa chikitsa jokyamtho moolyaankanam chese uddesyamto upayoginchabadindi. kandaraala kuurpu mariyu suukshmadarshini nirmaanam vyaadhitho paatu marutayi, mariyu vyaadhi pathology phalitamgaa sambhavinche impedencelo maarpulanu eeem kolustundi. chikitsalu mariyu nivaaranala aavishkarananu vegavantam cheyadaaniki ankitamaina 501 (sii) (3) laabhaapekshaleni samstha prize 4 life dwara alls biomarker (biological correlate ledhaa surrogate end point anie kooda pilustaaru) gaa daani saamardhyaaniki em pratyaekamgaa gurtinchabadindi. $1 millionla biomarker chhalenj anedi biomarkernu gurtinchadampai drushti saarinchindi, idhi rendava dasha aushadha pareekshalanu sagaaniki tagginchenta khachitamainadi mariyu nammadaginadi. eee bahumatini daa. beth izrael looni neurology vibhaagamlo neuromuscular disease vibhagam adhipati seward rutkov, deconness medical center loe neurology professor mariyu haarvard medical schoollo neurology professor, eem yokka saanketikatanu abhivruddhi cheyadamlo mariyu daani nirdishta anuvartanaanni abhivruddhi cheyadamlo ayana chesina krushiki. biomarkerga eeem anedi kotta chikitsalanu marinta vaegamgaa mariyu samarthavantamgaa gurtinchadaaniki daariteestundani bhaavistunnaaru. redikyulopati, inflammatory mayopati, duechen kandaraala ksheenata mariyu vennemuka kandaraala ksheenatatoo sahaa vividha rakaala naraala kandaraala paristhitulalo vyaadhi sthithiki eem sunnitatvaanni choopinchindi.
naraala kandaraala vyaadhi anchanaatho paatu, kandaraala paristhiti yokka soukaryavantamaina mariyu sunnitamaina kolatagaa panichese avakaasam kooda eeenku undhi. vruddhaapya janabha mariyu keella gayalu unna vyaktulalo pani cheyadam valla kandaraala ksheenata mariyu viniyogaaniki chaalaa sunnitamgaa untundani mariyu kandaraala conditioning mariyu hypertrophieki sunnitamgaa untundani suuchistumdi. tudi antariksha nauka mission (ess. tii. ess-135) loe elukala adhyayanamtho sahaa eluka mariyu elukala namuunaalapai pani cheyadam eee sambhaavya viluvanu nirdhaarinchadaaniki sahaayapadindi.
antarleena bhavanalu.
vidyut nirodhakatapai aasakti 20va sataabdam prarambham nundi undhi, sareeradharma shaastravetta luis lapic naraala kanaala poranu roopondinchadaaniki praathamika circuitnu pratipaadinchaaru. 1940 varaku saastravettalu eee namuunaapai vaividhyaalatoe prayogaalu chesaaru, kenneth cole kana poralu mariyu kanaantara dravam rendinti yokka nirodhakata lakshanaalaku kaaranamayye circuit namuunaanu abhivruddhi chesaaru.
anni impedence-aadhaarita paddhatula maadirigaane, arsi circuitga kandara kanajaalam yokka saralikruta namuunaapai immig aadharapadi untundi. eee namuunaa circuit yokka nirodhakata bhaganni bahya kana mariyu kanaantara dravaala nirodhakataku mariyu praticharya bhaganni kana pora yokka capacitive prabhaavaalaku aapaadistundi. vyaktigata kana pora yokka samagrata kanajaalam yokka impedence paie gananeeyamaina prabhavanni chooputundi; anduvalla, vyaadhi purogatilo kanajaalam yokka ksheenatanu kolavadaniki kandaraala impedensenu upayoginchavacchu. naraala kandaraala vyaadhiloo, vividha karakalu kandaraala kuurpu mariyu suukshma nirmaana amsaalanu prabhaavitam chestaayi, veetilo mukhyamgaa kandaraala fiber ksheenata mariyu avyavastha, kandaraala ksheenatalo sambhavinche kovvu mariyu bandhana kanajaalaala nikshepana mariyu vaapu undatam, aneka itara vyaadhulu unnaayi. em kanajaalamlo eee maarpulanu bahula pounahpunyaalalo mariyu pradhana kandaraala fiber disaku sambandhinchi bahula koonaalaloo daani impedence lakshanaalanu kolavadam dwara mottam kanajaalamlo eee maarpulanu sangrahistundi.
lakshyam loe, impedence anedi resistance mariyu reactains gaa vaeru cheyabadutundi, daani nijamaina mariyu oohaatmaka bhagalu. dheeni nundi, kandaraala dasanu lekkinchavacchu, idhi kandaraala gundaa velletappudu sinusoid edurkone samaya-maarpunu suuchistumdi. icchina nirodhakata (r) mariyu praticharya (x) kosam, dasha (θ) nuu lekkinchavacchu. prastuta paniloo, yea vyaadhulanu adhyayanam chestunnaru mariyu saanketika parignaanaanni elaa vartimpajestunnaaru anae daanipai aadharapadi moodu paaraamitulu mukhyamaina paatra pooshistunnatlu kanipistaayi.
kandaraala praantam meeda charmam mandam mariyu charmamloni kovvu undatam kooda eemnu prabhaavitam cheyavachu. ayithe, electrode designlanu srushtinchavachu, ivi prabhavanni chaalaa varaku tappinchagalavu mariyu tadwara ippatikee praathamika kandaraala daetaanu andistaayi. antekakunda, bahula pounahpunya kolatala vadakam kooda kandaraala nundi kovvu yokka prabhavalanu veruchese eee prakriyaku sahaayapadutundi. eee samacharam nundi, icchina praantamloo kandaraalapai unna kovvu yokka sumaru mottaanni anchanaa veyadam/lekkinchadam kooda saadhyamavutundi.
bahula pounahpunya kolatalu.
nirodhakata mariyu praticharya rendoo signal yokka input frequencipy aadharapadi untaayi. frequencylo maarpulu nirodhakata (dravam) mariyu praticharya (pora) yokka saapeksha sahakaranni impedenseku maarustaayi kabatti, multy frequency eeem vyaadhi gurinchi marinta samagra anchanaanu anumatinchavacchu. aarogyakaramaina mariyu vyaadhigrasta samuuhaala madhya pounahpunya aadhaarapadatamlo thedaalanu pradarsinchadaaniki pratighatana, praticharya ledhaa dasanu pounahpunya vidhiga roopondinchavacchu. vyaadhigrasta kandaraalu perugutunna pounahpunyamtho praticharya mariyu dasalo perugudalanu pradarsistaayi, ayithe aarogyakaramaina kandaraala praticharya mariyu dasha viluvalu 50-100 kz varaku pounahpunyamtho perugutaayi, eee samayamlo avi pounahpunyam yokka vidhiga taggadam praarambhistaayi. icchina kandaraala kosam frequency spectramnu nirnayinchadaaniki 500 heartz nundi 2 megahertz varaku frequencylu upayoginchabadataayi.
kandaraala anisotropy.
kandara kanajaalam yokka vidyut nirodhakata anisotropic; kandaraala fiberlaku samaantaramgaa pravahinche current fiberlaku addamgaa artogonalga pravahinche current kante bhinnamgaa pravahistundi. kandaraala antataa artogonalga pravahinche current ekkuva kana poralanu edurkontundi, tadwara nirodhakata, praticharya mariyu dasha viluvalanu penchutundi. kandaraala fiberlaku sambandhinchi vividha koonaalaloo kolatalu teesukovadam dwara, icchina kandaraala anisotropeeni nirnayinchadaaniki eeemnu upayoginchavacchu. anisotropeeni kandaraala fibers disaku sambandhinchi konam yokka vidhiga graph plaat nirodhakata, reactains ledhaa dasagaa ledhaa icchina impedence karakam yokka rekhansha kolata (kandaraala fiberlaku samaantaramgaa) kuu viloma (fiberlaku lambamgaa) kolata nishpattigaa choopabadutundi.
kandaraala anisotropy kooda naraala kandaraala vyaadhitho maarutundi. neuromuscular vyaadhi rogula anisotropy profiles mariyu aarogyakaramaina niyantranala madhya vyatyaasaanni eim choopinchindi. adanamgaa, mayopathik mariyu neurogenic vyaadhi madhya vivaksha chuupadaaniki eeem anisotropeeni upayoginchavacchu. vividha rakaala naraala kandaraala vyaadhulu pratyaekamaina anisotropeelanu kaligi untaayi. mayopati vyaadhi anedi taggina anisotropy dwara vargeekarinchabadutundi. neurogenic vyaadhi takkuva oohinchadagina anisotropeeni utpatti chestundi. atyalpa dasha yokka koonaanni samaantara sthaanam nundi maarchavacchu, mariyu mottam meeda anisotropy tarachugaa aarogyakaramaina niyantrana kante ekkuvagaa untundi.
kolata vidhanalu.
saadhaaranamgaa, eee saanketikatanu vartimpajeyadaaniki, kaneesam naalugu uparitala electrodelu aasaktigala kandaraalapai unchabadataayi. bayati rendu electrodelalo oka nimisham pratyaamnaaya current vartinchabadutundi, mariyu voltage signals lopali electrodela dwara namodu cheyabadataayi. vartimpajesina current yokka frequency mariyu pradhana kandaraala fiber disaku electrode shreni yokka sambandham maarutuu untundi, tadwara kandaraala yokka puurti bahula-pounahpunyam mariyu bahula-disaatmaka anchanaanu saadhinchavachchu.
aneka vibhina impedence vislaeshanha parikaraalatoe eim nirvahinchabadindi. bio impedence vislaeshanha kosam upayoginche vaanijyaparamgaa andubaatulo unna vyavasthalanu, vyaktigata kandaraala impedensenu kolavadaniki kramaankanam cheyavachu. signalnu utpatti cheyadaaniki lock-inn amplifiernu upayoginchi tagina impedence analysernu kooda anukuuleekarinchavachchu mariyu uparitala electrodela nundi voltagelanu record cheyadaaniki tectronics p6243 vanti takkuva saamarthyam gala probnu kooda nirminchavacchu.
ayithe, aasaktigala kandaraalapai jagrattagaa electrode sthaanaanni mariyu electrodela tappu amarika mariyu khachitatvam yokka sambhaavyatanu batti ituvanti paddhatulu nemmadigaa mariyu vikrutamgaa vartistaayi. tadanugunamgaa, electrode headtho bahula bhaagaalanu upayoginchi prarambha chethitho pattukune vyavasthanu nirminchaaru, dheenini neerugaa rogipai unchavacchu. eee parikaram electrode plaetla shrenini kaligi undhi, veetini ekapaksha dhoranulalo impedence kolatalanu nirvahinchadaaniki empikagaa sakriyam cheyavachu. aasileskoplu oka sammelanam sinusoid signalnu utpatti cheyadaaniki programme cheyabaddaayi, idhi vegavantamaina forier transform dwara ekakaalamlo bahula pounahpunyaala vadda impedensenu kolavadaniki upayoginchabadutundi.
aaa prarambha vyavastha srushtinchabadinappati nundi, kandaraala naanhyata (ledhaa mq) viluvanu lekkinchadamtho sahaa, naraala kandaraala vyaadhi anchanaa mariyu fitness paryaveekshanha rendintiloonuu upayoginchadaaniki shilpam vanti itara handheld vaanijya vyavasthalu abhivruddhi cheyabadutunnayi. eee taruvaati viluva kanajaalam yokka icchina cross-sectional praantaaniki kandaraala saapeksha saktini utpatti chese saamarthyam yokka sumaru anchanaanu andinchadam lakshyamgaa pettukundi. udaaharanaku, kandaraala naanhyata anedi sarkopeniya anchanaalo upayoginche kolata.
praamaanika bioelectrical impedence vislaeshanhatoe polchandi.
eim vanti praamaanika bioelectrical impedence vislaeshanha (biah) kooda maanava sareeram yokka lakshanaalanu kolavadaniki balaheenamaina, adhika pounahpunya vidyut pravahanni upayogistundi. praamaanika bialo, em kakunda, chetulu mariyu kaallapai unchina electrodela madhya vidyut pravaham pravahistundi mariyu mottam current maargam yokka impedence lakshanaalu kolustaaru. anduvalla, kolichina impedence lakshanaalu saapekshamgaa anirdishtamainavi, endukante avi sariiramlooni chaalaa bhaganni, antya bhagalu, chaatii, pottikadupu mariyu pottikaduputo sahaa kaligi untaayi; tadanugunamgaa, sannani shareera dravyarashi mariyu% kovvu yokka mottam shareera kolatalanu matrame andinchavacchu. antekakunda, bialo, current athi takkuva nirodhakata maargamlo prayaanistundi, anduvalla prastuta marganni marche evaina karakalu detaalo vaividhyam kaligistaayi. udaaharanaku, pedda naukala vistarana (udhaa.zii., siralu) perugutunna aardreekaranhatho takkuva-nirodhakata marganni andistundi, tadwara phalita daetaanu vakreekaristundi. adanamgaa, pottikadupu vishayaalalo maarpulu adevidhamgaa daetaanu maarustaayi. shareera sthaanam kooda gananeeyamaina prabhavalanu kaligi untundi, ummadi sthaanam detaalo vaividhyaalaku dohadam chestundi. lakshyam, dheeniki viruddhamgaa, vyaktigata kandaraala uparitala amsaalanu matrame kolustundi mariyu sareeram ledhaa avayavaala sthaanam ledhaa aardreekarana sthithi dwara saapekshamgaa prabhaavitam kaadu. amyotrophic lateral sclerosis (alls) loe oka adhyayanamlo eeem mariyu praamaanika biah madhya thedaalu udaaharanagaa cheppabaddayi, idhi 60 mandhi rogulalo purogatini samarthavantamgaa track cheyagaligindani, ayithe biah kaadani choopinchindi.

