terrie elton

terrie ess. elton ohiyo state universitylo pharmacologyki american professor.
vidya mariyu vidya charitra.
terrie elton oka jeevarasaayana shaastravetta, athanu thana bii.ess. webber state university nundi chemistrylo, athani Ph.dii. washington state university nundi biochemistrylo, mariyu washington state university mariyu alabama vishwavidhyaalayamlo post doctoral panini pradarsinchaaru. 2019 natiki elton dorothy emm vadda formacy professor mariyu parisoedhakudu. ohiyo raashtramlo davis haart und lung research institute.
shaastreeya dushpravartana.
elton thana prachurinchina rachanalalo konni chitraalu vakreekarinchabadinatlu kanipinchina taruvaata taruvaata shaastreeya dushpravartanaku modati aaropanalu edurkonnadu, mariyu ohiyo rashtra formacy vibhagam kamitee antargata daryaaptuku gurayyadu. kramarahita" chitraalu "uddesapurvaka dushpravartana" phalitamgaa levani vishwavidyaalaya daryaaptu kamitee nirdhaarinchina taruvaata elton modata dushpravartana aaropanala nundi vimukti pondaadu.ayithe, december 2012 chivaralo, elton ohiyo state university adhikarulu mariyu parisoedhanaa samagrata karyalayam rendinti dwara shaastreeya dushpravartanaku doshigaa nirdhaarinchabaddaadu. down syndrome unna rogula medadu rasayana saastramlo thana parisoedhanaloo keelaka proteinlanu gurtinchadaaniki upayoginchina westran blatslo tappudu dayta unnatlu kanugonabadindi. jaateeya aarogya samsthalaku manjuru chesina darakhastulo westran blat daetaanu kooda ayana abaddhalu chepparu. elton yokka detapai samakhya daryaaptu nayakudu zaan dahlberg prakaram, "adhikara sthaanam nundi idhi spashtamgaa undhi. niyantrana mariyu prayogaatmaka paristhitulanu suuchimchadaaniki elton bommalanu tirigi upayoginche deerghakaala sampradaayam undhi. athanu coppy chesinatlu, recise chesinatlu/stretch chesinatlu/kudinchabadindani, cheekatigaa mariyu tippabadina chitraalanu (addamgaa mariyu niluvugaa) kooda kanipistaadu... saaruupyatalanu daachadaaniki."
daachadaaniki." parisoedhana samagrata karyalayam elton prachurinchina aaru patraalanu upasamharinchukovaalani sifaarasu chesindi, mariyu athanu swachchandamgaa moodu samvatsaraala minahaayimpu oppandamloki pravesinchaadu, dheenilo athanu yea yuu thoo edainaa oppandaalu ledhaa upa oppandaala nundi tananu taanu minahayinchukunnadu.ess. prabhutva samstha mariyu prajaarogya sevalaku yea ruupamloonainaa salahadaruga panicheestunnaaru. ohiyo state university kooda eltonku thana sonta jarimaanaalanu vidhinchindi, indulo moodu samvatsaraala paatu edainaa under graduate ledhaa graduate vidyaarthulanu paryaveekshinchadaanni nishedhinchadam, anni patraalanu samarpinchadam mariyu aidu samvatsaraala paatu vaaritho munduku saagadaaniki mundu sameeksha kosam vishwavidhyaalayaaniki darakhaastulanu manjuru cheyadam, mariyu parisoedhana dushpravartanapai counselling puurti cheyadam mariyu parisoedhana naitikatapai sikshana.
2020 natiki, elton yokka edu parisoedhanaa patraalu upasamharinchabaddaayi.
patraalanu upasamharinchukunnaaru.
chromosome 21-utpanna micrornalu maanava down syndrome medadulalo asaadhaarana protein vyakteekaranaku kaaranaatmaka aadharaanni andistaayi.
eee vyaasam journal off biological chemistrylo prachurinchabadindi. eee kaagitamlo, elton mariyu athani prayogasaala aidu microrna janyuvulatho panicheestunnaayi. 21 kaligi unna mirna janyuvu yokka nishkriyaatmakata, down syndrome chikitsalo chikitsa saadhananni andinchavacchani soochinche antima phalitaalu. eee patrika modatisaarigaa november 6,2009naa prachurinchabadindi. patrikanu upasamharinchukune samayaniki, idhi ippatike 34 saarlu udaharinchabadindi. udaharinchabadindi, 2sii, 2dii, 3bii, 3ii, 3ii, 4zii mariyu mariyu chitraalalo tappudu mariyu/ledhaa kalpita "westran blats" kaaranamgaa kaagitam upasamharinchabadindi.
maanava chromosome 21-utpannamaina miranalu down syndrome medadulu mariyu hrudayaalalo atigaa vyakteekarinchabadataayi.
eee vyaasam vaerae patrikalo prachurinchabadindi. eee kaagitamlo, down syndrome janyu motaadu atigaa vyaktaparachadam valla 21 mirna anedi nirdishta lakshya proteinla yokka vyakteekarana taggadaaniki kaaranamavutundani, idhi down syndrome rogulu anubhavinche neuronal mariyu cardiac lakshanaalaku kaaranamavutundani parikalpana. eee patrika modatisaarigaa april 1,2008naa prachurinchabadindi. patrikanu upasamharinchukune samayaniki idhi ippatike 74 saarlu udaharinchabadindi. udaharinchabadindi, 3bii, 3sii, 3eff, 3ii mariyu 3zhe chitraalalo tappudu mariyu/ledhaa kalpita paaschaatya macchala kaaranamgaa kaagitam upasamharinchabadindi.
maanava angiotensin II rakam 1 grahakam 1166 a/c bahuroopata microrna-155 bindingnu taggistundi.
eee vyaasam journal off biological chemistrylo prachurinchabadindi. elton prayogasaala chesina eee adhyayanam modati saadhyamayye jeevarasaayana yantraamgaanni andinchindi, dheeni dwara + 1166 a/c polymorphism 1r saandrata mariyu bahusha hridaya sambandha vyaadhula perugudalaku daariteestundi. eee patrika modata juun 21,2007naa prachurinchabadindi. patrikanu upasamharinchukune samayaniki idhi ippatike 184 saarlu udaharinchabadindi. prachurana yokka 6va chitramlo tappudu mariyu/ledhaa kalpita paaschaatya macchala kaaranamgaa kaagitam upasamharinchabadindi.
amaramaina maanava trophoblast kanaalalo eah. tii. 1 grahaka janyuvu yokka transcriptional regulation
eee vyaasam biochimica ett biophysica acta ledhaa bba (laatinlo biochemical mariyu biophysical journal) loe prachurinchabadindi. eee vyaasam oka amaramaina maanava trophoblast kana rekha yokka aavishkarananu vivaristundi, idhi mruduvaina vascular kandaraala sankocham, dravam homeostasis mariyu saanubhootigala naadii karyakalapalanu niyantrinche peptide ayina aanjeeki pratispandistundi. idhi maavilo samslaeshanha cheyabadutundani (pindaaniki poeshakaalu mariyu neetini istundi) parisoedhana suuchistumdi, idhi takkuva trophoblast aakramanaku anumatinche janyuvunu penchutundi, idhi preclampsiaku pradhana kaaranam. chitram chitram kalpita macchalu kaaranamgaa kaagitam upasamharinchabadindi. idhi aarusaarlu udaharinchabadindi.
maanava maanava grahakam yokka yokka niyantrana mrna splies vaeriyantlu exon 2 nii kaligi unnaayi
eee vyaasam molecular und cellular endocrinologylo prachurinchabadindi. anedi mrna transcripts loe exon 2 nuu cherchadam valla anedi protein sthaayilu mariyu aang II yokka pratispandana elaa taggutundo eee vyaasam charchistundi. మానవఆr kriyaaseelata hridaya sambandha vyaadhitho daggari sambandham kaligi undhi, pratyaamnaaya spliesing dwara exon 2 nuu cherchadam anedi anedi protein yokka mottam utpattini tagginchadaaniki mariyu మానవఆr kriyaaseelata yokka sambhaavya rogalakshana prabhavalanu parimitam cheyadaaniki oka kotta yantraamgaanni suuchistumdi. 5, 5, 6bii, 7bii chitraalalo kalpita macchalu kaaranamgaa eee kaagitam upasamharinchabadindi. eee patrika 11 saarlu udaharinchabadindi.

