
aah-7921

ah-7921 anedi oka opioid analgesic aushadham, idhi micro-opioid graahakaaniki empika cheyabadindi, noti dwara icchinappudu marphin yokka shakti 90 saatam untundi. dheenini 1970laloe united kingdamlo unna allen mariyu hunberries vadda oka brundam kanugonnadi. eee aushadhaanni kotta psychoactive padaardham (nps) gaa pariganistaaru, dheenilo idhi niyantrita padaarthaalanu anukarinchadaaniki prayogasaalalo krutrimamgaa srushtinchabadutundi. eee padaardham 2012 nundi internetlo "research chemical" gaa kooda vikrayinchabadindi. aanlainlo vikrayinchinappudu dheenini pratyaamnaaya paeru doxylama anie pilavavacchu, doxylaminetho ayomayam chendakudadu. 7921 ennadoo clinical trials kuu purogati saadhinchaledu. united stateslo etuvanti vaidya upayogam gurinchi deeeku teliyadu, mariyu eee padaardham yokka upayogaala gurinchi etuvanti vaidya parisoedhananu nirvahinchaalani aarogya mariyu maanava sevala vibhagam (hetchhets) nii pattubattaledu.
dushprabhaavaalu mariyu upasamharana.
saadhaaranamgaa 10 nundi 150 mg varaku unde motaadulatoe, viniyogadaarulu heraine, marphin mariyu fentanil vanti euphoria mariyu swaasakosha maandyam vanti prabhavalanu anubhavinche avakaasam undhi. adhika motaadu sambhavinchinappudu viniyogadaarulu tarachugaa tachicardia, adhika raktapotu mariyu muurchalanu anubhavistaaru. elukalu, kukkalu mariyu kothulu, pareekshalalo upayoginchabaddaayi, ivi aushadham marphineku daadaapu samanamga saktivantamainadigaa choopinchaayi mariyu chaalaa nitaruga motaadu pratispandana vakratanu kaligi unnaayi. elukalaku aidu rojula paatu rojuku moodu saarlu 20 mg motaadulu ivvabadataayi, itara opiyaayidla maadirigaane upasamharana lakshanaalanu anubhavistaayi. eee aushadham nundi vaidoliginappudu viniyogadaarulu niraasa mariyu nidralemiki guravutaarani nivedikalu choopinchaayi.
chemistry.
ah-7921 saadhaaranamgaa 215-216 o celsius madhya draveebhavana binduvutoe off-white ghanamgaa kanipistundi. idhi 4 rotable baandlatoe kuudina oke samayojaneeya bandham kaligina unit. dheeniki rendu hydrogen bandham sweekarthalu mariyu oka hydrogen bandham daata kooda unnaaru.
upayoginchandi.
abhivruddhi chendutunna samstha dwara, maanavulalo kakapoyinappatiki, vitrolo mariyu jantuvulalo 7921 vistrutamgaa adhyayanam cheyabadinappatiki, idhi vaidya upayogam kosam vaanijyaparamgaa eppuduu vikrayinchabadaledu. 2013loe, japaanlo "synthetic ganjai" utpattulalo kriyaaseela padaardhamgaa upayoginchinatlu kanugonabadindi.
october 2015loe, yajamani-sikshakudu raay sedlesk sikshana pondina rendu gurralu (bassman mariyu litreta) belmont park resatraaklo 7921kii positivga pareekshinchabaddaayi. norway mariyu island eee padaardhaanni vislaeshanhaatmaka suuchana pramaanamgaa upayogistaayi, dheenilo rasayana sarafaraadaarula nundi aanlainlo arder cheyavachu; ayithe, idhi maanava viniyogam kosam kaadani, tadwara chattaniki anugunamgaa undani lebullu paerkonaali. 2013-2014 nundi padhi nelallo, naalugu ververu deshaala nundi eee aushadham nundi teevramaina maranaalu namodayyayi. modati maranam 19 yella purushudu, athanu gunde raktam yokka 3.9 mg/l ah-7921 saandrata kaligi unnadu, idhi maranam opioid matthu anie nirdhaarinchadaaniki vaidya pareekshakulaku daariteesindi. maroka sandarbhamlo, oka 22 yella mahila 450 microgramula/lii yokka emukala raktamtho ah-7921 gaadatatoo chanipoyinatlu kanugonabadindi.
prachurinchina kesu nivedikala yokka 2018 sameekshalo mottam 14 kesulu kanugonabaddayi, veetilo 13 maranaaniki daariteesaayi. paripalana yokka moukhika maargam rendu kesulalo nivedinchabadindi, mariyu chaalaa sandarbhaalalo sahavarti aushadha agentla vadakam nivedinchabadindi. postmortem shavapareekshalalo pulmonary edema atyanta saadhaaranamainadani kanugonabadindi, tommidi kesulalo oopiritittulu bhaareega unnayani kanugonnaru. mottammeeda, toda raktamlo takkuva mariyu adhika saandrata kaligina ehech-7921 thoo maranaalu sambhavinchaayi.
chattabaddhata.
australialo 2014 maeloe ah-7921 (mandulu mariyu vishaala ekareeti scheduling kosam pramaanamlooni schedule 9) cheyabadindi. ayithe eee savarana juun 2014loe raddu cheyabadindi, antey savarana patram aagipotundi, conny vaastava scheduling pradhana patramlo bhaagamgaa saasvatamgaa untundi (anni suspemp savaranalu konni vaaraala tarvaata aagipotaayi). ayithe, idhi ippatikee nishedhinchabadina digumati kaavacchu.
2013 december nundi ijrayello pampinhee cheyadam chattaviruddham.
united kingdamlo, aushadhaala durviniyoga chattam 1971 (savarana) (nem. 2) arder 2014.
brazillo, 2015 mae nundi ehech-7921 oka akrama aushadham.
october 2015 natiki chainaalo ah-7921 anedi niyantrita padaardham.
check republicklo 7921 nishedhinchabadindi.
united stateslo, vaidya upayogam lekapovadam valla 2016 mae 16naa niyantrita padaarthaala chattam yokka schedule Iloe ah-7921 unchabadindi. inca, padaarthaanni tayaaru chesi, pampinhee chesi, digumati chesi, egumati chesi, parisoedhana chesi, daanini upayoginchadaanni avagahana cheyalanukune yea vyakti ayina aushadha amalu yantraangam dwara namodu cheyabadaali.
kenadian niyantrita mandulu mariyu padaarthaala chattam 2016loe padaarthaanni schedule ii padaarthamgaa chaerchadaaniki savarinchabadindi. chattaparamaina adhikaram lekunda swaadheenam chesukovadam valla garishtamgaa 7 samvatsaraala jailu siksha vidhinchavachhu. inca, aarogya kenada 2016 mae nelaloo "aahara mariyu aushadha nibandhanala" nuu savarinchi, ehech-7921 nuu nirbandha aushadhamgaa vargeekarinchindi. chatta amalu samstha unnavaaru, minahaayimpu anumati unna vyakti ledhaa mantri adhikaram unna samsthalu matrame kenadaalo aushadhaanni kaligi undavacchu.

