homeosis

parinaamaatmaka abhivruddhi jeevasaastramlo, homeosis anedi oka avayavanni maroka avayavamgaa marchadam, idhi konni abhivruddhi klishtamaina janyuvulalo, mukhyamgaa homeotic janyuvulalo utparivartana ledhaa missexpression nundi utpannamavutundi. jantuvulalo, eee abhivruddhi janyuvulu pratyaekamgaa vaati anteroposterior akshampai avayavaala abhivruddhini niyantristaayi. ayithe, mokkalalo, homeosis dwara prabhaavitamaina abhivruddhi janyuvulu kesaramu ledhaa rekula abhivruddhi nundi chlorophyll abhivruddhi varaku deeninainaa niyantrinchavacchu. jantuvulalo kanipinche hocks janyuvulalo utparivartanalu ledhaa mokkalalo mods-baaks kutumbam vanti itara kaaranaala valla homeosis sambhavinchavachhu. homeosis anedi keetakaalu unnanta vijayavantamgaa mariyu vaividhyamgaa maaradaaniki sahayapadina oka lakshanam.
abhivruddhi samayamlo vibhaga gurtimpunu marchadam dwara homeotic utparivartanalu panicheestaayi. udaaharanaku, "ultrabithorox" janyuroopam oka samalakshanaanni istundi, indulo metathorasic mariyu modati pottikadupu bhagalu mesothorasic vibhagaluga marutayi. maroka prasiddha udaaharana "antenapedia": function yokka geyin-off-function yugmavikalpam antenna sthaanamlo kaallu abhivruddhi chendadaaniki kaaranamavutundi.
vrukshashaastramlo, rolf sattler puurti homeosisto paatu pakshika homeosisku praadhaanyata ivvadam dwara homeosis (bharti) bhavananu savarinchaaru; eee savarana ippudu vistrutamgaa aamodinchabadindi.
angiospermlaloni homeotic utparivartanaalu adavilo arudugaa untaayani bhavistaruh vaarshika mokka clarkia (onagrassi) loe, homeotic utparivartanalu telisinavi, ikkada rekulanu sepal-lanty avayavaala rendava valayamtho bharti chestaaru, idhi oke janyuvu yokka utparivartanalo udbhavistundi. pushpa utparivartanalo praanaantakamaina ledhaa haanikaramaina parinaamaalu lekapovadam valla vibhina padanirmaana vyakteekaranalu "clarkia" yokka parinaamaaniki mariyu bahusha aneka itara mokkala samoohaalalo kooda oka karakamga unnaayi.
jantuvulalo homeotic yantraamgaalu.
edd levis homeotic utparivartanakaarulapai chesina pani taruvaata, aneka homeotic proteinlalo unna samrakshinchabadina dna binding kramaanni kanugonadam dwara jantuvulalo homeosis yokka drugvishayam marinta vivarinchabadindi. 
anduvalla, 60 amaino aamlam dna binding protein domainku homeodomine anie paeru pettaru, ayithe 180 bipi nucleotide sequence encoding dheeniki homeobox anie paeru pettaru. edd levis adhyayanam chesina homeobox janyu samuuhaalaku hocks janyuvulu anie paeru pettaru, ayinappatikee chaalaa ekkuva homeobox janyuvulu hocks janyu samuuhaala kante janthu janyuvula dwara encode cheyabadataayi.
antonio garsia-bellido pratipaadinchina vidhamgaa konni proteinla homeotic-function modata "selector" gaa bhaavinchabadindi. 
nirvachanam prakaram, selectorlu (transcription phyaaktar) proteins anie oohinchabaddaaru, ivi kanajaalamlo oka kanam mariyu daani kanajaala vaarasulaku rendu sambhaavya kana bhavishyattu loe okadaanni sthiramgaa nirnayistaayi. 
chaalaa janthu homeotic vidhulu homeobox-kaligina kaarakaalato mudipadi unnappatikee, jantuvulalo anni homeotic proteins homeobox janyuvula dwara encode cheyabadavu, inca anni homeobox janyuvulu tappanisarigaa homeotic vidhulu ledhaa (utparivartana) samalakshanhaalato mudipadi undavu.
homeotic selectorla bhavananu maikhel acom "post-selector zeane" modal anie pilavabade vaatilo marinta vivarinchaadu ledhaa kaneesam arhata pondaadu, idhi adanapu phalitaalanu cherchindi mariyu selector-aadhaarita sthiramaina binary switchla "sanaatana" nii "venakki nadichindi".
kanajaala compartmentla bhavana homeosis yokka selector modaltho lothugaa mudipadi undhi, endukante sell vidhi yokka selector-madhyavartitva nirvahananu jantuvu yokka shareera pranaalika yokka vividha samsthaagata vibhagaluga parimitam cheyavachu.
eee sandarbhamlo, homeotic selectorlu mariyu abhivruddhi sankethaala yokka vividha kalayikala dwara saha-lakshyamgaa unna enhancer dnlpy drushti pettadam dwara albert erives mariyu sahacharulu homeotic yantraamgaalapai kotta antardrushtulanu kanugonnaru.
eee pani homeotic selectorlugaa panichese transcription kaarakaalaku, naach signalling maargam mariyu bmp signalling maargam vanti abhivruddhi signalling maargaala prabhavakaalugaa panichese transcription kaarakaalaku madhya protein jeevarasaayana vyatyaasaanni gurtistundi.
eee pani homeotic selectorlu parimita kanajaala compartmentlo "licenses" enhancer dnlaku panicheestaarani pratipaadinchindi, tadwara enhancerlu abhivruddhi sankethaalanu chadavadaaniki veelu kalpinchabadataayi, ivi polyglutamine-madhyavartitva aggregation dwara vileenam cheyabadataayi.
mokkalalo homeotic yantraamgaalu.
jantuvulalo kanipinche sanklishta bahula kanajaalam maadirigaane, bhuu mokkala bahula kanajaalam abhivruddhi chendutuu, homeotic prabhaavaalato transcription karakam janyuvula dwara kanajaalam mariyu avayava vibhagaluga vyavastheekarinchabadutundi.
mokkalu homeobox kaligina janyuvulanu kaligi unnappatikee, mokkala homeotic karakalu mods-baaks dna binding domainlanu kaligi untaayi.
janthu janyuvulu kooda takkuva sankhyalo mads-baaks kaarakaalanu kaligi untaayi.
anduvalla, mokkalu mariyu jantuvulalo bahula kanajaalam yokka swatantra parinaamamlo, vividha eucariotic transcription phyaaktar kutumbaalu homeotic vidhulanu nirvahinchadaaniki saha-empika cheyabaddaayi. 
mods-domine karakalu marinta pratyaekamaina kaarakaalaku saha-karakaluga panicheyaalani pratipaadinchabaddaayi, tadwara avayava gurtimpunu nirnayinchadamlo sahaayapadataayi.
idhi maikhel acom vivarinchina janthu homeotics yokka vivaranaku marinta daggaragaa anugunamgaa pratipaadinchabadindi.

