
transcription babul

transcription babul anedi dna transcription samayamlo dna double helix yokka parimita bhaagam gayapadinappudu erpadina paramaanu nirmaanam. transcription babul parimaanam 12 nundi 14 bays jatala varaku untundi. rna polymerase enjaim oka pramotartho bandhinchi, rendu dna tantuvulu vidipovadaaniki karanamainappudu transcription babul erpadutundi. idhi janta laeni dna praantaanni andistundi, ikkada double helix yokka prati strandpy nucleotidela yokka chinna saagateeta bahirgatamavutundi. 
rna polymerase.
transcription babul erpadatamlo palgone pramukha enjaim ayina bacteria rna polymerase, rna samshlaeshanhaku maarganirdesam cheyadaaniki dna templetnu upayogistundi. idhi rendu pradhana roopaallo untundih core enjaimga, idhi kriyaarahitamgaa unnappudu, mariyu holloenzymga, idhi sakriyam ayinappudu. sigma (σ) karakam anedi transcription prakriyaku sahayapade oka upa vibhagam mariyu idhi transcription budaganu jatha cheyani sthaavaraalatho bandhinchinappudu sthireekaristundi. eee rendu bhagalu, rna polymerase mariyu sigma karakam, kalisi jatha chesinappudu, rna polymerase holloenzymnu nirmistaayi, idhi daani kriyaaseela roopamlo untundi mariyu pramotartho bandhinchadaaniki mariyu dna transcription praarambhinchadaaniki siddhamgaa untundi. okasari idhi dnatho bandhinchina tarvaata, rna polymerase closed nundi open complexga maari, transcription babul nuu yerparustundi. rna polymerase kotta strand yokka 3 'chivarana paripuurakaramaina sthaavaraalanu jodinchadam dwara 5' nundi 3 'disalo kotta rnanu samslaeshanha chestundi. transcription praarambhamaina tarvaata holoenzyme kuurpu vidipotundi, ikkada σ karakam sanklishtatanu vidadeestundi mariyu rna polymerase, daani pradhana roopamlo, DNA anuvu venta jaarutundi.
bacterial rna polymerase yokka transcription saikil.
rna polymerase holoenzyme bahirgatamaina dna strand yokka pramotartho bandhistundi mariyu rna yokka kotta strandnu samslaeshanha cheyadam praarambhistundi. double helix dna shidhilamgaa untundi mariyu prati strandpy chinna nucleotide sequence andubaatulo untundi. transcription babul anedi bahirgatamaina dna tantuvulalo okadaanipai jatacheyani sthaavaraala praantam. prarambha pratilekhana sthaanam holloenzyme oka pramotartho bandhinche pradaesam dwara nirnayinchabadutundi. prarambha pradaesamloe dna gayapadani mariyu oke-strandedga untundi. rna polymerase template dna strand krindiki kadulutundi mariyu sigma karakam vidudala cheyabadinappudu dna promoter paraspara charyaku antaraayam kaligistundi. praarambhaaniki σ karakam avasaram, conny DNA transcription yokka migilina dasalaku kaadu. σ karakam rna polymerase nundi vidipoyina tarvaata, transcription konasaagutundi. idhi podugu dasaku velladaaniki kotta rna strand yokka sumaru 10 samslaeshanha nucleotidelu avasaram. podugu samayamlo lipyantareekarana prakriya chaalaa vaegamgaa untundi. rna polymerase oka termination signal (terminator) nii chuse varaku podigimpu jarugutundi, idhi prakriyanu addukuntundi mariyu dna template mariyu kotta rna anuvu rendinti vidudalaku kaaranamavutundi. dna saadhaaranamgaa mugimpu sanketaanni encode chestundi.
eucariotic transcription.
chaalaa varaku eucariotic janyuvulu rna polymerase II dwara lipyantareekarinchabadataayi, ivi 5 'nundi 3' disalo konasaagutaayi. eucariotslo, rna polymerase II complexes lopala unna nirdishta upabhaagaalu bahula vidhulanu nirvahinchadaaniki anumatistaayi. saadhaarana transcription karakalu rna polymerase II nundi dnaku bandhinchadaaniki sahaayapadataayi. transcription praarambhinchadaaniki rna polymerase II bandhinche chota mariyu eucariotslo, transcription prarambha sthaanam + 1 nucleotide vadda unchabadina chota promoterlu udaharinchabaddaaru. anni rna polymerasela maadirigaane, idhi 3 'nundi 5' disalo dna template venta prayaanistundi mariyu kotta rna yokka 3 'chivaraku kotta sthaavaraalanu jodinchadam dwara 5' nundi 3 'disalo kotta rna strandnu samslaeshanha chestundi. double stranded dna unwinding phalitamgaa transcription babul sambhavistundi. dna double strand yokka sumaru 25 bays jatala gayapadina taruvaata, transcription babul praantamloo rna samslaeshanha jarugutundi. suupar coiling kooda eee prakriyaloo bhaagam, endukante rna polymerase II mundu unna dna praantaalu vishraanti teesukuntaayi, ayithe daani venuka unna dna praantaalu rewinding avtayi, mallii double helixnu yerparustaayi.
rna polymerase transcription chakram samayamlo ekkuva dasalanu nirvahistundi, mukhyamgaa transcription babul nii paripuurakaramaina bays jatha kosam terichi unchadamlo. transcription sykillo konni dasalu unnaayi, veetilo ekkuva proteins avasaram, udaaharanaku arpibi4/7 complexes mariyu elangation phyaaktar transcription phyaaktar iis (tfis) kii jatacheyabadina rna polymerase.