
myocyte-nirdishta penche karakam 2a

myocyte-nirdishta enhancer phyaaktar 2eah anedi maanavulalo "meaf2eah" janyuvu dwara encode cheyabadina protein. meaf2eah anedi meaf2 kutumbamlo oka transcription karakam. maanavulalo idhi chromosome 15q26 loe untundi. meaf2elo konni utparivartanalu coronary artary vyaadhi mariyu myocardial inforction yokka autosomal aadhipatya roopaaniki kaaranamavutaayi.
function.
mesodermal puurvagaami kanaala nundi myoblastlaku bhedam yokka prakriya kandaraala janyu vyakteekarananu niyantrinche vividha kanajaala-nirdishta kaarakaalanu kanugonadaaniki daariteesindi. mayod (mim 159970), myogenin (mim 159980), maif5 (mim 159990), mariyu mrf4 (mim 159991) thoo sahaa myogenic basic helix-loop-helix proteins gurtinchabadina kaarakaala yokka 1 taragati. DNA binding regulatory proteinla yokka rendava kutumbam myocyte-nirdishta enhancer phyaaktar-2 (Mef2) kutumbam. eee proteinlalo prati okkati, annee kakapoyina, aneka niyantrana praantaalalo unna meph2 target dna shreniki bandhistundi. meph2 janyuvulu mods janyu kutumbaaniki chendinavi (eest matting rakam-nirdishta transcription karakam mcm1, mokkala homeotic janyuvulu 'agamus' mariyu 'deficience' mariyu maanava seeram pratispandana karakam srf (mim 600589)), aneka homeotic janyuvulu mariyu itara transcription karakalu kooda kaligi unna oka kutumbam, ivanni rakshita dna-binding domaine panchukuntaayi.[omim dwara sarafara cheyabadindi]
paraspara charyalu.
myocyte-nirdishta enhancer phyaaktar 2a thoo sankarshana chendutundani choopabadindihi

