
barton-mccomby deoxygenation

barton-mccomby deoxygenation anedi oka sendriya praticharya, dheenilo oka sendriya sammelanamloni hydroxy functional group sthaanamlo hydrogen nuu unchi alkyl groupunu istundi. dheeniki british rasayana saastravettalu surr derec harrold richard barton mariyu stewart doubleu. mccomby.
eee deoxygenation praticharya oka radikal pratyaamnaayam. sambandhita barton decorboxylationlo reactant anedi carboxylic aamlam.
yantraangam.
praticharya yantraangam utpreraka radikal prarambha dasha mariyu pracharam dasanu kaligi untundi. alkahal (1) modata theonoester ledhaa janthet 2 vanti reactive carbotheoil intermediatga maarchabadutundi. aibn vaedi cheyadam valla daani homolitic cheelika erpadutundi, rendu 2-sanoprop-2-yl radicals 9 nuu utpatti chestundi, ivi prati okkati tributylstanine 3 nundi oka protaannu sangrahinchi tributylstanil radicals 4 mariyu kriyaarahitamaina 10 nuu utpatti chestaayi. tributyltine radikal sulfur anuvu vadda 4 daadi dwara 2 nundi santhet samuuhaanni sangrahistundi. idhi carbon kendrikruta raadikalnu vadili, r-o σ bandham yokka homolitic cheelika dwara c-o π bandhaanni yerparustundi, idhi alkyl radikal 5 mariyu tributylitine janthet 7 nuu istundi. eee sammelanamloni sulfur tinn bandham chaalaa sthiramgaa untundi mariyu eee praticharyaku chodaka saktini andistundi. alkyl radikal 5 appudu tributylstanen yokka kotta anuvu nundi hydrogen anuvunu sangrahistundi, idhi kaavalasina deoxygenated utpattini (6) mariyu pracharam kosam siddhamgaa unna kotta radikal jaatulanu utpatti chestundi.
vaividhyaalu.
pratyaamnaaya hydrogen vanarulu.
eee praticharya yokka pradhana pratikuulata emitante, vishapuuritamaina, khareedaina mariyu praticharya misramam nundi tolaginchadam kashtam ayina tributylstanen vadakam. oka pratyaamnaayam emitante, tributyltine oxidenu radikal muulamgaa mariyu paalii (methylhydridesyloxance) (pmhs) nuu hydrogen muulamgaa upayoginchadam. prarambha padaarthamgaa upayoginche phenyl chlorotheonopharmate chivariki carbonyl sulfidenu utpatti chestundi.
trialkyl borenlu.
takkuva mottamlo neetitho kalushitamaina trimethyl boren vanti trialkilborane-water complexelu marinta soukaryavantamaina hydrogen daatanu andistaayi.
eee utpreraka chakramlo trialakilboren 3 gaali dwara methyl radikal 4kii gaali aakseekarana dwara pratispandana praarambhamavutundi. eee radikal janthet 2 nundi s-methyl-s-methyl diethio carbonate 7 mariyu radikal intermediate 5. (ch3) 3b thoo pratispandistundi.eee radikal thoo tirigi kalapadaniki hydrojannu hetch2oo complexes 3 andistundi, idhi diethyl borinic aamlam mariyu kotta methyl radikal nuu vadilivestundi.
boran-water complexelo oo-hetch homolysis praticharya anedi tributylstanenlone homolysis praticharya maadirigaane saktitoe endothermic anie, conny swachchamaina neeti yokka homolysis praticharya kante chaalaa takkuvagaa untundani saiddhaantika gananala dwara kanugonabadindi.
paridhi.
eee praticharya yokka vaividhyam azadirachtin yokka mottam samshlaeshanhaloo dasalalo okatigaa upayoginchabadindih
maroka vaividhyamlo karakamu imidazole 1,1 '-theocarbonyldemidazolo (tii. sii. dii. ii), udaaharanaku palescencin bii yokka mottam samshlaeshanhaloo. sugandha sextetlo natrajani lonepare prameyam unnanduna janthet yokka pratidhvani sthireekarana lenanduna praathamika alcoholsku tii. sii. dii. ii. mukhyamgaa manchidi.
eee praticharya "s"-alkailksanthetlaku kooda vartistundi. triathyl boren oka kotta loha rahita karakamga, avasaramaina hydrogen anuvulu protic draavakaalu, reactor goda ledhaa (khachitamgaa nirjala paristhitulalo) boraine nundi kooda sangrahinchabadataayi.

