
nutritional epigenetics

nutritional epigenetics anedi janyu vyakteekarana mariyu chromatin praapyatapai poeshanha yokka prabhavalanu adhyayanam chese shaastram. idhi epigenetic sanghatanalapai bioactive phud bhagala prabhavalapai drushti saarinche poeshaka janyusaastram yokka upavargam.
charitra.
pindam poeshanha valla pillala janyu profile maarpulu dutch karuvu 1944-1945 lone gamaninchabaddaayi. garbhinii tallulalo poeshakaahaara lopam kaaranamgaa, eee karuvu samayamlo janminchina pillalu gunde jabbulu, oobakaayam, schizophrenia, niraasa mariyu vyasanam vanti aarogya samasyalanu pradarsinche avakaasam ekkuvagaa undhi.
jeevasaastravettalu randy girtle mariyu robbert eah. 2003loe "molecular und cellular biology" anae parisoedhanaa patrikalo garbhinii talli aaharam valla aame santaanam yokka janyu vidhulapai padee prabhavalapai vaari parisoedhananu prachurinchina taruvaata jalabhoomi poeshaka epigeneticslo prarambha maargadarsakulugaa maarindi.
parisoedhana.
poeshaka epigeneticsloni parisoedhakulu aahaaramloni anuvulu mariyu janyu vyakteekarananu niyantrinche anuvula madhya paraspara charyanu adhyayanam chestaaru, idhi dietary methyl groupulu mariyu dna methylation vanti kendrikruta praantaalaku daariteestundi. poeshakaalu mariyu bioactive aahara bhagalu dna methylation mariyu histone maarpulaku sambandhinchina enzymatic charyanu nirodhinchadam dwara epigeneticsnu prabhaavitam chestaayi. methyl samuuhaalu avaanchaneeya janyuvulanu anachiveyadaaniki upayoginchabadataayi kabatti, talli aahara methyl viniyogam sthaayi aame pillala janyu vyakteekarananu gananeeyamgaa maarchagaladu, mukhyamgaa prarambha abhivruddhi samayamlo. antekakunda, oka vyakti yokka vayojana jeevitaantam eee prakriya konasaagutunnanduna poeshakaahaaram methylation prabhaavitam chestundi. eee kaaranamgaa, poeshaka epigeneticistlu aaharaanni molecular exposure yokka oka roopamgaa adhyayanam chesaaru.
epigenetic prakriyalanu prabhaavitam chese bioactive phud bhagalu eah, bii6 mariyu bii12 vanti vitaminla nundi alkahal mariyu arsenic, cadmium mariyu selenium vanti muulakaala varaku untaayi. adanapu folic aamlam mariyu collin vanti aahara methyl supplements kooda epigenetic janyu niyantranapai pratikuula prabhavalanu chuuputaayi.
paadarasam mariyu lead praadhamika epigenetic karakalu vanti bhaarii lohalaku aahara bahirgatam autism mariyu attension deficit hyperactivity desorderku daariteestundani parisoedhakulu pariganinchaaru. garbhadhaarana samayamlo adhika kovvu mariyu takkuva protein aaharaalu kooda sisuvulalo oobakaayam pramaadaanni penchutaayi. phytochemicals viniyogam cancer kanaalanu nirodhinche epigenetic aadhaarita yantraamgaalanu kooda sanukoolamgaa prabhaavitam chestundi. nutritional epigenetics mariyu majer depressive desorder yokka pathophysiology madhya sambandhaanni kooda parisoedhana suuchimchimdi.
epigenetic stressors.
maanavulalo epigenetic yantraamgaala taraala prasaaraaniki sambandhinchina aadharalu 2008loe shampine dwara modatisaarigaa charchinchabaddaayi, aahara abhadrata anedi oka rakamaina ottidi, idhi DNA methylation namoonaalalo maarpula dwara janyu vyakteekarananu prabhaavitam chestundi. maroka rakamaina ottidi anedi paelavamaina prasavapurva aaharam, idhi poeshaka lopam mariyu pindam epigenetic reprogrammingku daariteestundi, idhi pillala jeevitamlo taruvaata vyaadhula abhivruddhiki blueprintnu srushtistundi. bhougolika praantaanni batti, aahara naanhyata samasyalu aahara heavy metal exposurelatho sambandham unna methylation namoonaalalo maarpula dwara epigenetic vaarasatvaanni prabhaavitam cheyavachu, mukhyamgaa autism mariyu attension deficit hyperactivity desorders (ADhd) vishayamlo.
aahara abhadrata.
aahara abhadrata anedi praathamika avasaralanu teerchadaaniki taginanta aaharaanni pondalekapovadaanni suuchistumdi mariyu idhi dna methylation namuunaalatoe sambandham unna puttukatho vachhe lopaala pramaadaanni penchutundi. aahara abhadratatho unna garbhinii talli aardhika ottidilo undi, thana poeshaka avasaralanu teerchukoovadaaniki taginanta aaharaanni pondalekapovacchu. aame bhougolika sthaanam aahara edaarilo undavacchu, akkada aameku taginanta surakshitamaina mariyu pooshakamaina aaharam dorakadu. aahara edaarulu aahara abhadratatho mudipadi unnaayi mariyu adhika saandrata kaligina faast phud restaurantlu mariyu muulalooni dukaanaalu takkuva dharalaku anaarogyakaramaina adhika proses chesina aaharalanu matrame andistaayi.
paelavamaina prasavapurva aaharam.
paelavamaina prasavapurva aaharam ledhaa anaarogyakaramaina aaharam DNA methylation namuunaalanu prabhaavitam chestayani mariyu pillalalo type 2 diabetes, ADHD mariyu prarambha pravartana samasyala abhivruddhiki dohadam chestundani choopabadindi.  dna methylation namoonaalalo maarpulaku daariteese anaarogyakaramaina prenatal diet yokka lakshanaalu adhika kovvu/chakkera ultra-processed aahara utpattulanu ekkuvagaa teesukovadam, poeshakaalu adhikamgaa unde mottam aaharalanu (udhaa.zii. pandlu mariyu kuuragaayalu). garbhadhaarana samayamlo adhika kovvu mariyu takkuva protein aaharaalu kooda sisuvulalo oobakaayam pramaadaanni penchutaayi. adanapu folic aamlam mariyu collin vanti aahara methyl supplements kooda epigenetic janyu niyantranapai pratikuula prabhavalanu chuuputaayi. prastuta prapancha aahara vyavastha kalushitamaina, asurakshitamaina mariyu marchabadina aaharaalu anaarogyakaramaina aahaaramto mudipadi unna atyanta saadhaarana karakallo okatigaa undatam valla maanava aarogyaanni pratikuulamgaa prabhaavitam chese samasyalatho baadhapadutondi.
aahara naanhyata.
aahara naanhyata samasyalu desham, aahara bhadrata paddhatulu, mariyu bhaarii lohaalu, purugumandula avasheshaalu mariyu itara pramaadakaramaina bahirgatam gurinchi tayari mariyu vyavasaya nibandhanalanu batti oka bhougolika praantam nundi maroka praantaaniki maarutuu untaayi. purugumandulu mariyu bhaarii loha avasheshaalu vanti rasayana pramaadaalaku gurikavadanni tagginchadaaniki, prapancha vaanijya samstha (doublutio) surakshitamaina aahara vaanijyaaniki haamii ivvadaaniki prayatninche codex alimentarius commission jaarii chesina uttama paddhatula sankethaalanu erpaatu cheyadaaniki deshaala madhya oppandaalanu spaansar chesindi.  uttama paddhatulu upayogamlo unnappatikee, heavy metal mariyu purugumandula avasheshaalu ippatikee aahara sarafaraalo kanipistaayi.  anaarogyakaramaina aaharaala phalitamgaa akarbana paadarasam mariyu seesam avasheshaalaku prasavaniki mundu mariyu prasavaanantara aahara bahirgatam autism mariyu ADHD unna pillalalo mukhyamaina janyu pravartanalanu sthiramgaa prabhaavitam chestundani choopabadindi. prasavapurva organophosphate purugumandula bahirgatam cardio-metabolic vyaadhula abhivruddhiki sambandhinchina janyuvulalo dna methylation prabhaavitam chestundani choopabadindi.