
fstl1

folistatin-sambandhita protein 1 anedi maanavulalo "fstl 1" janyuvu dwara encode cheyabadina protein.
nirmaanam.
eee janyuvu folistatin anae bii. emm. pii-4-binding proteintho saaruupyata kaligina proteinnu encode chestundi. idhi bMP-4 mariyu tgf-β1 thoo bandhistundi, conny a loe sakriyam kaadu. indulo efs module (10 samrakshinchabadina systeine avasheshaalanu kaligi unna folistatin lanty kramam), kajal-rakam serin protease inhibitor domine, 2 ef hanned domainlu mariyu vaan willebrand phyaaktar rakam sii domine unnaayi.
clinical praamukhyata.
abhivruddhi.
oopiritittula abhivruddhi, moothra naalaala abhivruddhi, kendra naadii vyavastha abhivruddhi mariyu asthipanjara abhivruddhi vanti abhivruddhilo fstl1 paatra undhi.
arthuritis.
eee janyu utpatti rheumatoid aartharaitistho sambandham unna auto antigen anie bhaavistaaru.
arthuritis yokka pathologylo mukhyamaina shotha nirodhaka madhyavartulanu fstl1 niyantristundi, mariyu fstl1 yokka seeram sthaayilu arthuritis teevratatoo sambandham kaligi untaayi.
hridaya sambandha vyaadhulu.
fstl1 proteinku cardioprotective paatra unnatlu telustondi. ottidi overload taruvaata fstl1 hypertropheny tagginchindi mariyu ischemia/reperfusion yokka eluka ledhaa pandhi namoonaalo myocardial ischemia/reperfusion gayanni nirodhinchindi. kandaraala nundi pondina fstl1 gaayaaniki pratispandanagaa vascular punarnirmananni modulate chestundi.
myocardial inforction taruvaata punarutpattini prerepinchadaaniki saadhyamayye chikitsagaa fstl1 spashtamaina saamarthyaanni kaligi unnatlu choopabadindi. myocardial inforction tarvaata prayogaatmaka jantuvulaku (eluka mariyu pandhi) fstl1 thoo chikitsa cheyadam dwara kramamga gunde paniteerunu punaruddharinchaaru, kaneesam kontavaraku saadhaaranamgaa vibhajinchani gunde kandaraala kanaala pratiruupananu prerepinchadam dwara

