
zeane-francois rosignol

zeane-francois rosignol oka french shaastravetta, aushadha rasayana shaastravetta mariyu vaidyudu, septembaru 5,1943naa fraanslo janminchaaru. athanu paris vishwavidhyaalayamlo chaduvukunnadu, taruvaata ushnamandala vaidyamlo pratyekata pondaadu. aaa taruvaata athanu vidyaasamsthalalo mariyu aushadha parisramalo vruttini konasaginchadu, bahula aushadha nirodhaka "falsiparam" malaria ledhaa albendazole mariyu nitazoxanide chikitsalo halophantrin vanti paraannajeevi vyaadhula chikitsa kosam kotta aushadhaalanu kanugoni abhivruddhi chesaadu. 1993loe, athanu thana sonta aushadha samstha, romark laboratories, ell.sii., theazolideslo modatidi ayina thana sonta aavishkarana nitajoxanide abhivruddhi cheyadaaniki. romarklo, athanu company directorla boardu chhairman mariyu daani cheef sains officer. theazolides yokka antiviral karyakalapalanu kanugonna taruvaata rosignol californialoni stanford vishwavidhyaalayaaniki interferon stimulated janyu margalu mariyu deerghakaalika viral hepatitisnu adhyayanam cheyadaaniki professor krinda vellaadu. emet keef mariyu professor. jeffrey glen. hepatitis sii vairasku vyatiraekamgaa nitazoxanide yokka antiviral kaaryaacharana yokka yantraangam glen prayogasaalalo kanugonabadindi.
vidya.
rosignol paris vishwavidhyaalayamlo professor aadhvaryamlo rasayana saastraanni adhyayanam cheyadam praarambhinchaadu. paal caudiot mariyu paarislooni radium institute yokka chemistry vibhaagamlo synthetic organic chemistrylo doctorate degreeni siddham chesaaru, idhi vaastavaaniki paster institute yokka radiobiology mariyu cancer parisoedhana vibhagam. 1911loe paster institute mariyu paris vishwavidyaalayanche srushtinchabadina radium institute, rendu taraala curies, modati pier mariyu maerii curie, taruvaata vaari kumarte, irene joliot-curie, mariyu aame bhartha frederic juliot, 1903 mariyu 1935 madhya aidu nobel bahumatulu geluchukunna sahaja mariyu krutrima rediyodhaarmikatanu kanugonna pradaesam. curie yokka vaarasatvamto lothugaa gurtinchabadindi, rosignol anhu bhouthika saastramlo vruttini konasaagistunnatlu bhaavinchaaru. radium institute mariyu prakkane unna curie foundation kooda oka pradhana cancer aasupatriki nilayamgaa unnaayi, ikkada maerii curie mariyu claudius regaud rediyamtho radiotherapyni praarambhinchaaru, idhi maerii kanugonna radium mariyu cancer yokka modati aadima chikitsalu ekkada vartimpajeyabaddaayi, chivariki, eee samvatsaraallo rosignol yokka vaidyaaniki gurikavadam athani aasaktini rekettistundi mariyu vaidya parisoedhana vaipu athani bhavishyat dhoranini nirnayistundi.
nitazoxanide.
paris vishwavidhyaalayamlo rasayana saastramlo thana vyasanni samarthinchukunna taruvaata, athanu vaidyasaastram adhyayanam cheyadaaniki paatasaalaku tirigi vacchaadu. radium institutelo thana chivari samvatsaramlo, rosignol, appudu paris vishwavidyaalayam yokka formacy paatasaalalo paraannajeevi shaastra professor ayina raymond caviernu kalusukunnaru, akkada athanu malaria mariyu pegu paraannajeevula chikitsa kosam kotta aushadhaala kosam paraannajeevi shaastra prayogasaalaku velutunnadu. cavier rasayana saastramlo doctorate degree kosam samslaeshanha cheyabadina konni sammelanaalanu pareekshinchaadu, mariyu athanu thana vaidya vidyanu konasagistune thana prayogasaalalo chaeradaaniki avakaasaanni andinchaadu. idhi manchi nirnayamgaa niroopinchabadindi, 1974loe rosignol mariyu javier theazolideslo modati nitajoxanide kanugonnaru. nitazoxanide modata cavier prayogasaalalo pareekshinchabadindi mariyu vitrolo ledhaa prayogasaala jantuvulalo pregu protojova mariyu helminths rendintikee vyatiraekamgaa prabhaavavantamgaa unnatlu kanugonabadindi mariyu fraanslooni maanavulalo "tainia saginata" mariyu "hymenolepsis naana" chikitsalo chinna sankhyalo rogulalo modatisaarigaa ivvabadindi.
ushnamandala vaidyamlo pani cheyandi.
1980 prarambha rojullo, rosignol professornu kalisaaru. fraanslooni maarsillo pier payne. payne thana vruttiparamaina jeevitaanni paschima aafrikaalo gadipadu, modata senegal looni dockerlo, taruvaata coat dii 'ivore looni abidjan loe, akkada athanu desham yokka modati vaidya paatasaalanu sthaapinchaadu mariyu chivariki daani modati deane ayyadu. marcille nundi, peane ushnamandala vaidyamlo sikshana pondina rosignol. intalo, philadelphia, pensylvanialoni pharmaceutical diggajam, smithcline & french prayogasaalalu, paarislooni cavier prayogasaalalo nirvahinchina paraannajeevi saastramlo pani gurinchi telusukuni, pegu helmintiasis chikitsa kosam benzemidazole carbamate anthelminthic, albendazolnu abhivruddhi cheyadaaniki rosignolnu baadhyata vahinchaayi. marcille nundi geniva varaku, idhi daani director, andrew davis aadhvaryamlo prapancha aarogya samsthalo paraannajeevi vyaadhula vibhaagaaniki oka chinna prayaanam matrame, mariyu akkada rendu pradhana paraannajeevi nirodhaka mandulu, progicontel mariyu albendazole, vaidyaparamgaa abhivruddhi cheyabadataayi. progiquantel anedi schistosomiasis chikitsalo oka pradhana purogatigaa maarindi, idhi paraannajeevi yokka aidu jaatulaku vyatiraekamgaa prabhaavavantamgaa untundi. albendazole anedi modati prabhaavavantamaina single motaadu nematocydal anthelminthic, idhi abhivruddhi chendutunna prapanchamlo atyanta vistrutamgaa upayoginche aushadhaalalo okati. eee rendu mandulu prapancha aarogya samstha yokka avasaramaina aushadhaala jaabitaalo cherchabaddaayi. rosignol tadupari 10 samvatsaraalu davisto kalisi panichestundi.
paarislooni caviertho kalisi panichestunnappudu, rosignol washington dii looni walter reed armi institute off research vadda unna united states armi research & development command yokka antimalarial drugg development prograamtho malaria nirodhaka agentla kosam kooda sodhinchaadu.sii. athanu antimalarial, halophantrinetho sainyam praarambhinchina panini puurti chesaadu mariyu eee prakriyaloo smithcline & french prayogasaalalato kuudina aushadha-sunnitamaina mariyu aushadha-nirodhaka falsiparam malaria chikitsa kosam paschima aafrikaaloni maali desamlo mariyu dakshina americaloni french gayanalo moodu baga niyantrita clinical adhyayanalanu nirvahinchaadu. albendazole mariyu halophantrine united stateslo aahara mariyu aushadha paripalana nundi varusaga albenza mariyu haaphan vaanijya paerlatoe vaari niyantrana aamodaalanu pondaayi mariyu prapanchavyaaptamgaa pedda sankhyalo deshaalalo licenses pondaayi. avi ippatikee smith cline & french prayogasaalala vaarasudaina glaxomithcline, plc dwara vaanijyeekarinchabaddaayi.
nitazoxanide mariyu itara theazolidela abhivruddhi.
1993loe, nitajoxanide maereelaandlooni bethesdaloni national institute off health vadda national institute off allergy und antu vyaadhula sahakaaramtho tirigi kanugonabadindi, idhi abhivruddhi chendutunna apicomplexion protojova, "cryptosporidium parvam" kuu modati prabhaavavantamaina chikitsa. dheenini taruvaata romark prayogasaalalu, ell.sii. roganirodhaka shakti mariyu roganirodhaka saktini tagginche vyaktulu, sahayalu unnavaaru, iddariloo. idhi chivariki united stateslo alinia anae vaanijya paerutoe 12 nelala vayassu nundi roganirodhaka shakti laeni peddalu mariyu pillala chikitsa kosam aahara & aushadha paripalana dwara aamodinchabadutundi.
nitazoxanide yokka antiviral karyakalapala aakasmika aavishkarana mariyu daani charya yokka yantraangam yokka aavishkarana rosignal jeevitamlo oka kotta adhyayanni terichindi mariyu paroksha antiviral aushadhaala yokka puurtigaa kotta taragati aavishkaranaku daariteesindi, idhi viral anuvaadaanni nirodhinchadaaniki telisina aneka interferon uddeepana janyu maargaalanu sakriyam chese host yokka roganirodhaka kanaala dwara interferranla utpattini prerepinchadamlo panichestundi. bahusha marinta aasaktikaramainavi, anukuula roganirodhaka saktipai mariyu marinta pratyaekamgaa tii lymphocytelu, bii lymphocytelu mariyu sahaja killer kanaalapai theazolides yokka prabhavalu. idhi united kingdamloni oxford vishwavidhyaalayamlo mariyu united statesloni jaateeya aarogya samsthalalo teevramaina parisoedhanaku sambandhinchina amsam mariyu aids vanti aneka itara vyaadhula chikitsalo kotta vidhaanaaniki daariteestundi, conny konni cancerlu ledhaa swayam pratirakshaka vyaadhulu kooda. romark prayogasaalalu united kingdamlo university off liverpool loe andreau stachulsky kinda nirvahinchina vandalaadi rendava taram theazolidela samshlaeshanhanu twaragaa praarambhinchaayi, mariyu rotavirus mariyu norovirus, influenzae mariyu influenzae vanti anaarogyaalu mariyu deerghakaalika viral hepatitis bii mariyu sii vanti viral enterrities vanti viral vyaadhula chikitsalo kotta utpannaalu ippudu clinical abhivruddhiloki pravesistunnaayi. nitazoxanide, theazolideslo modatidi, norovirus mariyu rotavirus mariyu respiratory syncitial virus valla kalige cryptosporidial diarrhoea, viral gastroenteritis kosam kanugonabadina mottamodati chikitsa. 2 nundi 12 nelala vayassu gala sisuvulaku ivvadaaniki idhi surakshitamgaa unnatlu kanugonabadindi.
gowravaalu mariyu puraskaralu.
united kingdamlo, daa. rosignol raayal society off chemistry (frsc), raayal college off pathologists (eforcipath) mariyu united kingdamloni raayal colleges off physicians (honefpm) yokka pharmaceutical medicine facultiki gourava sabhyudiga ennikayyaaru. athanu ushnamandala vaidyam mariyu parisubhrata yokka raaja samajam mariyu vaidya shaastram yokka raaja samaajamlo kooda sabhyudu. united stateslo athanu 200 samvatsaraala kritam kotta prapanchamlo srushtinchabadina puraatana vaidya sangham ayina college off physicians off philadelphia (eff. sii. pii. pii) loe sabhyudiga ennikayyaaru. athanu american society off tropical medicine und hygiene, american society pharr microbiology, american chemical society mariyu american association pharr dhi studdy off liver diseases loe sabhyudu. athanu peru looni national universidad dii kajamarka nundi gourava doctorate degreeni andukunnadu. kazamarka anedi andis parvathaalalo daachina nagaram, akkada athanu thana vaidya brundamtho kalisi ushnamandala paraannajeevi vyaadhulanu adhyayanam chesi chikitsa cheyadaaniki chaalaa samvatsaraalu gadipadu. sthaanika samaajamlo ayana chesina krushiki gaanu ayana jaateeya peruvian vaidya sangham ayina collegio medisi dell perulo gourava sabhyudiga kooda niyaminchabaddaaru. daa. rosignol aneka vishwavidyaalayaalatho bahula adhyapaka niyamakalanu nirvahinchaaru, conny murry mukhyamgaa united stateslo californialoni stanford vishwavidhyaalayamlo mariyu united kingdamloni oxford vishwavidhyaalayamlo, rendu samsthalu, akkada athanu thana praathamika mariyu clinical parisoedhanalanu chaalaa varaku nirvahinchaadu. ayana shaastreeya mariyu vaidya patrikalalo 100 kante ekkuva peer-reviewed kathanaalanu rachinchaaru mariyu antu vyaadhula chikitsa kosam kotta aushadhaalapai 31 united states petentlanu andukunnaru. 11 samvatsaraalu, athanu modata salahadaruga mariyu taruvaata switzerlandloni geneevaalo prapancha aarogya samstha kosam paraannajeevi vyaadhulalo nipunudigaa panicheesaadu. 1982 nundi ayana americalo nivasistunnaaru.