
amobarbital

amobarbital (gatamlo amylobarbitan ledhaa sodiyam amital anie karige sodiyam uppu anie pilicheevaaru) anedi barbiturate utpannam ayina aushadham. idhi upasamana-hypnotic lakshanaalanu kaligi untundi. idhi vaasana laeni tellani spatikaakaara podi mariyu konchem chedhu ruchi kaligi untundi. idhi 1923loe germanylo mottamodatisaarigaa samslaeshanha cheyabadindi. idhi chinna nundi madhyantara natana barbituratega pariganinchabadutundi. amobarbitalnu ekkuva kaalam teesukunte, saareeraka mariyu manasika aadharapadatam abhivruddhi chendutundi. amobarbital upasamharana anedi pracchanna prakampanalanu anukaristundi mariyu praanaantakam kaavacchu. amobarbitalnu americaloni elly lillie und company amital anae brand paerutoe prakaasavantamaina neelam bullet aakarapu capsules (pulviewls anie pilustaaru) ledhaa 50,100 ledhaa 200 milligramula aushadhaanni kaligi unna gulabi maatralu (disketlu anie pilustaaru) loe tayaaru chesindi. eee aushadhaanni kooda saadhaaranamgaa tayaaru chesaaru. veedhiloo "neelam swargam" anie piluvabade amobarbital vistrutamgaa durviniyogam cheyabadindi. amital, alaage tunal, samaana parimaanamlo secobarbital mariyu amobarbital kaligi unna kalayika aushadham, rendintinee 1990la chivari varaku eli lillie tayaaru chesindi. ayithe, benzodiazipines yokka prajaadarana peragadamtho, eee aushadhaala kosam prescriptions 1980la madhya nundi chivari varaku chaalaa arudugaa marai.
aushadha shaastram.
eluka thalamic mukkalalo "inn vitro" adhyayanamlo, amobarbital gaba grahakalanu sakriyam cheyadam dwara panichesindi, idhi input nirodhakata, depressioned burst mariyu tannic firingnu tagginchindi, mukhyamgaa ventrobasal mariyu intralaminar neuronlalo, adhe samayamlo vyaktigata chloride chaanellalo paeludu vyavadhi mariyu sagatu vaahakatanu penchutundi; idhi post synaptic pravaahaala yokka vyaapti mariyu kshayam samayam rendintinee penchindi.
reperfusion taruvaata mitochondrial paniteerunu samrakshinche prayatnamlo eluka gundelo mitochondrial electron ravaanaanu nirodhinchadaaniki oka adhyayanamlo amobarbital upayoginchabadindi.
1988 adhyayanam prakaram, amobarbital anedi secobarbital mariyu pentobarbital (avarohana kramamlo) kante takkuva saktitoe "inn vivo" loe benzodiazipine grahaka bandhaanni penchutundi, conny phenobarbital mariyu barbital (avarohana kramamlo) kante ekkuvagaa untundi. (secobarbital> pentobarbital> "amobarbital"> phenobarbital> barbital)
idhi 212mg/kilola sem elukalanu kaligi untundi.sii. 
jeevakriya.
amobarbital hydroxylation dwara 3 '-hydroxiamobarbital, mariyu enn-glucosidation dwara 1-(beata-dii-glucopyranosyl)-amobarbital erpadutundi.
suuchanalu.
aamodinchabadani/off-label.
intravenous maargam dwara nemmadigaa icchinappudu, sodiyam amobarbital trooth seeram anie pilavabadedigaa panichestundi. prabhaavamtho, oka vyakti saadhaarana paristhitulalo vaaru nirodhinche samacharanni bahirgatam chestaaru. idhi chaalaa varaku nirodham kolpovadam valla ayi undavacchu. anduvalla, manasika rogulalo nirodhakatalanu tappinchukovadaaniki wisconsin vishwavidhyaalayamlo vilium blequen eee aushadhaanni modata vaidyaparamgaa upayoginchaaru. oka vishayam sanghatana yokka "tappudu ghnaapakasakti" kaligi undataaniki balavantam cheyabadutundane aavishkarana kaaranamgaa amobarbitalnu nijamaina seeramgaa upayoginchadam viswasaneeyatanu kolpoyindi.
catatonic mutism unna rogulanu interview cheyadaaniki eee aushadhaanni sirala dwara upayoginchavacchu, konnisaarlu nidranu nivaarinchadaaniki kepheento kalipi.
rendava prapancha yuddham samayamlo shell shacku chikitsa cheyadaaniki mariyu sainikulanu mundu varusa vidhulaku tirigi ichhe prayatnamlo dheenini united states saayudha dalaalu upayoginchaayi. aushadham dwara prerepinchabadina saktivantamaina upasamanam, abhignaa balaheenata mariyu samanvayam kaaranamgaa eee rangamlo sainikula upayogaanni baga tagginchadamtho eee upayogam nilipiveyabadindi. amobarbital okappudu americalo elly lillie pharmaceuticals dwara amital brand paerutoe capsule roopamlo tayaaru cheyabadindi. idhi 80la praarambhamlo nilipiveyabadindi, ekkuvagaa benzodiazipine aushadhaala kutumbam dwara bharti cheyabadindi. amobarbital kooda vistrutamgaa durviniyogam cheyabadindi, veedhullo "neelam swargam" anie piluvabadevi endukante vaati neelam gulika.
vyatiraeka suuchanalu.
amobarbital teesukunetappudu eee krindi mandulanu nivaarinchaali
paraspara charyalu.
amobarbital anedi harmonela janana niyantrana prabhavalanu taggistundani telisindi.
adhika motaadu.
adhika motaadu yokka konni dushprabhavalalo gandaragolam (teevramainadi); praticharyala taggudala ledhaa nashtam; magata (teevramainadi); jwaram; chiraaku (konasagimpu); takkuva shareera ushnograta; paelavamaina teerpu; swaasa aadakapovadam ledhaa nemmadigaa ledhaa ibbandigaa swaasa teesukovadam; nemmadigaa hridaya spandana; aspashtamaina prasangam; asthirata; nidralo ibbandi; kalla asaadhaarana kadalikalu; balaheenata (teevramainadi). teevramaina adhika motaadu jokyam lekunda maranaaniki daariteeyavachchu.
rasayana shaastram.
amobarbital (5-eethail-5-isomyelabarbituric aamlam), anni barbituratela maadirigaane, malonic aamlam utpannaalanu euria utpannaalato pratispandinchadam dwara samslaeshanha cheyabadutundi. mukhyamgaa, amobarbitalnu tayaaru cheyadaaniki, α-ethyl-α-isomyelmalonic eestar euriatho (sodiyam ethoxide samakshamlo) pratispandinchabadutundi.
samajam mariyu samskruti.
thana priyuraalini gonthu nulimi champina, amaayakuraalani cheppukunna andres inglish-howard vanti hantakulanu doshigaa nirdhaarinchadaaniki dheenini upayoginchaaru. athanu thana nyaayavaadi rahasyamgaa aaa aushadhaanni icchaadu, daani prabhaavamtho athanu aamenu enduku gonthu nulimi champado, yea paristhitulalo anie velladinchaadu.
1951 augustu 28 raatri, natudu robbert walker yokka house keeper athanu bhavodvega sthithilo unnatlu kanugonnadu. aame walker yokka manoroga vaidyudini pilichindi, athanu vacchi nidramondinchadaaniki amobarbital icchaaru. walker thana bhavodvega visphotanaaniki mundu madyam sevinchaadani, amobarbital mariyu madyam kalayika teevramaina pratispandanaku daariteesindani nammutaaru. phalitamgaa, athanu oopiri peelchukoni, swaasanu aapivesaadu, atanni punarujjeevimpajeyadaaniki chesina anni prayatnaalu viphalamayyayi. walker 32 samvatsaraala vayasulo maraninchaadu. 
british natudu mariyu hasyanatudu toney hancock 1968loe australialo madyamtho kalipi eee aushadhaanni upayoginchi aatmahatya chesukunnadu.
elly lillie amital brand paerutoe amobarbitalnu tayaaru chesindi, idhi 1980laloe nilipiveyabadindi, dheeni sthaanamlo ekkuvagaa benzodiazipine aushadhaala kutumbam vachindi. amytal kooda vistrutamgaa durviniyogam cheyabadindi. amobarbital veedhi paerlaloo "blues", "blue angels", "blue birds", "blue devils" mariyu "blue heavens" unnaayi, endukante vaati neelam gulika kaaranamgaa.
saamskrutika suuchanalu.
lenn dieton yokka 1967 navala "eah competiable plays tuu dye" loe, amital mariyu lsd kalayikanu paerulaeni kathaanaayakudu thana karyakalapala gurinchi prashninchadaaniki pratispandinchelaa cheyadaaniki upayogistaaru.
thamus pinchon yokka 1973 navala "gravities rainbo" loe, sodiyam amitalnu sainika nigha vibhagam 1930laloe thana sonta raashtramaina masachusetslo (adhyayam 1) african-americanlaku vyatiraekamgaa tella americanla jaatyahamkaarampai tyrone slothrope (navala yokka kathaanaayakudu) aalochanalanu velikiteese oka rakamaina satya seeramgaa upayoginchindi.
1994 haasya action thriller true laislo, kathaanaayakudu harry taskarku (arnald schwarzenegger pooshinchina) ugravaadulu prasninchinappudu sodiyam amitalnu trooth seeramgaa istaaru.
2001loe, oka chikitsakudu (shirley nait) ayina "episode" nipankti () thana rogiki "sodiyam amital" thoo chikitsa chestundi. paatra daa. (bidi wang) eee aushadham rogiki salahaku chaalaa avakaasam istundani, chikitsakudu rogilo tappudu ghnaapakaalanu amarchagaladani paerkonnaadu.
2003loe, animated syries sealab 2021 season 3, episode 7, "tourist season", daa. quentin q. brett butler gaatradaanam chesina quin, paryaatakula samuuhamloo smrutibhramsaanni prerepinchadaaniki "sodiyam amital" nuu upayogistaadu, capt kundella medadu pathakam phalitamgaa sealubpy charyalu teesukokunda nirodhinchadaaniki. marfi. athanu paryatakulu bayaludere mundu uchita madya paaneeyamlo motaadunu vidichipettina bahumatigaa istaadu, mariyu parimaanamlo athanu "enugu marachipovadaaniki kaaranamavutundi" anie vivaristaadu. 
2005loe vacchina chitramlo, pradhana virodhi thana koduku maranaaniki kaaranamani taanu vishwasinche vyaktulanu rahasyamgaa mattumandu ivvadaaniki "sodiyam amital" nuu upayogistaadu, mariyu vaarilo teevramaina bhraantulanu prerepistaadu.
2022loe, daan braun yokka "kolpoyina chihnam" yokka "diophantine maaruperu", episode 06loe, sodiyam amitalnu siah trooth seeramgaa upayogistundi.