glucose transporter

glucose transporterlu anevi plasma pora antataa glucose ravaanaanu sulabhataram chese pora proteinla yokka vistruta samuuham, eee prakriyanu sulabhataram chesina vyaapti anie pilustaaru. anni jeevulaku glucose oka mukhyamaina shakti vanaru kabatti, eee ravaanaadaarulu anni failaalo untaaru. glut ledhaa ledhaa kutumbam anedi chaalaa ksheerada kanaalalo kanipinche protein kutumbam. 14 gluts maanava janyuvu dwara encode cheyabadataayi. glut anedi oka rakamaina uniporter transporter protein.
uchita glucose samslaeshanha.
chaalaa autotrophic kaani kanaalu uchita glucosenu utpatti cheyalevu endukante avi glucose-6-phosphatase yokka vyakteekarananu kaligi undavu mariyu anduvalla, glucose teesukovadam mariyu catabolismlo matrame palgontayi. saadhaaranamgaa hepatocytelalo matrame utpatti cheyabadutundi, upavaasa paristhitulalo, pregulu, kandaraalu, medadu mariyu moothrapindaalu vanti itara kanajaalaalu gluconiogenesis kriyaaseelata taruvaata glucosenu utpatti cheyagalavu.
eest loe glucose ravana.
saccaromysis serevisia" loe glucose ravana sulabhataram cheyabadina vyaapti dwara jarugutundi. ravana proteins pradhanamgaa hcxt kutumbaaniki chendinavi, conny aneka itara ravaanaadaarulu gurtinchabaddaaru.
ksheeradaalalo glucose ravana.
gluts anevi plasma pora yokka cytoplasmic vaipu bahirgatamayye amaino mariyu carboxyl termini rendintitho 12 pora-vistarinchi unna helix kaligi unna samagra pora proteins. glut proteins pratyaamnaaya kuurpu yokka namuunaa prakaram glucose mariyu sambandhita hexoselanu ravana chestaayi, idhi transporter kanaaniki velupala ledhaa lopali vaipu oke uparitala bandhinche pradaesaanni bahirgatam chestundani anchanaa vestundi. oka pradaesaaniki glucosenu bandhinchadam anedi ravaanaaku sambandhinchina conformational maarpunu prerepistundi mariyu glucosenu poraku maroka vaipuku vidudala chestundi. antargata mariyu bayati glucose-binding saitlu, transmembrane vibhagalu 9,10,11 loe unnatlu anipistundi; alaage, edava transmembrane vibhaagamlo unna dls muulaamsam ravana cheyabadina uparitalam yokka empika mariyu anubandhaanni kaligi undavacchu.
rakalu.
prati glucose transporter isopharm glucose gvakriyalo oka nirdishta paatra poeshistumdi, idhi daani kanajaala vyakteekarana, uparitala vishishtata, ravana gatisastram mariyu vividha saareeraka paristhitulalo niyantrita vyakteekarana dwara nirnayinchabadutundi. eee roeju varaku, 14 mandhi mandhi sabhyulu gurtinchabaddaaru. kramam saaruupyatala aadhaaramgaa, samruddhi kutumbam moodu upavargaalugaa vibhajinchabadindi.
I taragati.
modati taragatilo manchi lakshanaalatoo kuudina glucose transporterlu transporterlu untaayi.
taragatulu II/III.
rendava taragati krindi vaatini kaligi untundih
moodava taragati krindi vaatini kaligi untundih
rendava mariyu moodava taragatulaloni chaalaa mandhi sabhyulu iteevala databasela yokka homology shodhanalu mariyu vividha janyu prajectulu andinchina krama samacharam dwara gurtinchabaddaaru.
eee kotta glucose transporter isopharmla paniteeru prastutam inca spashtamgaa nirvachinchabadaledu. vaatilo chaalaa varaku varaku, mariyu) muulaamsaalatoe tayaaru cheyabaddaayi, ivi vaatini kanaantaramgaa nilupukovadamlo sahaayapadataayi mariyu anduvalla glucose ravaanaanu nirodhistaayi. eee ravaanaadaarula kana-uparitala sthaanaantaragamanaanni prothsahinchadaaniki yantraamgaalu unnaya anedi inca teliyadu, ayithe insulin insulin mariyu mariyu kana-uparitala sthaanaantaragamanaanni prothsahinchadani spashtamgaa nirdhaarinchabadindi.
sodiyam-glucose cottransport aavishkarana.
aagashtu aagashtu, praaglo, robbert keey. pregulalo glucose shoshanaku yantraamgaa sodiyam-glucose cottransportnu kanugonna vishayanni crain modatisaarigaa pradarsinchindi. crain yokka cottransport aavishkarana jeevasaastramlo fluxes coupling yokka mottamodati pratipaadana. pratipaadana crain kriyaaseela ravaanaanu vivarinchadaaniki cottransport bhavananu roopondinchina modatidi. pratyaekamgaa, brush sarihaddu pora antataa pegu epitheliumlo glucose perukupovadam anedi brush sarihaddu daatina diguva naa + ravaanaatoe jatacheyabadi untundani ayana pratipaadinchaaru. eee parikalpana vaegamgaa pareekshinchabadindi, suddhi cheyabadindi mariyu vaastavamgaa prati kana rakamloki vibhina shreni anuvulu mariyu ayanla churukaina ravaanaanu kaligi undataaniki [vistarinchabadindi].

