
arcc5

dna repair protein, expi-zii kanaalanu puurti chese protein anedi maanavulalo "ersisi5" janyuvu dwara encode cheyabadina protein.
function.
tolagimpu marammattu cross-complementing elukala marammattu lopam, complementation group 5 (geroderma pigmentosum, complementation group zii) yuvi-prerita dna nashtam yokka tolagimpu marammattulo paalgontundi. utparivartanalu kakain syndromeku kaaranamavutaayi, idhi teevramaina perugudala lopaalu, manasika mandagamanam mariyu cachexia dwara vargeekarinchabadutundi. vibhina isopharmlanu encoding chese bahula pratyaamnaaya spliesed transcript vaeriyantlu vivarinchabaddaayi, ayithe anni variantla jeeva praamaanikata nirnayinchabadaledu.
ersisi5loe utparivartanalu arthrogriposis kuu kaaranamavutaayi.
xpg anedi oka nirdishta nirmaana endonucles, idhi nucleotide tolagimpu marammattu samayamlo debbatinna nucleotide yokka 3 'vaipu DNA nii kotha chestundi.
syndromes.
ersisi5" ("expigy") janyuvulo utparivartana lopaalu cancer-peedita paristhiti geroderma pigmentosum (expi) kii matrame kaaranam kaavacchu ledhaa teevramaina neurodevelopmental desorder kakain syndrome (cs) ledhaa shishu praanaantaka cerebro-okyulo-facio-skelital syndromtho kalipi undavacchu.
mouse modal.
oka "ersisi5" ("expigy") utparivartana eluka namuunaa kaaleyam mariyu medadu rendintiloonuu ksheeninchina samalakshanhaalato kuudina cachexia mariyu bolu emukala vyaadhi sahaa akaala vruddhaapya lakshanaalanu pradarsinchindi. eee utparivartana elukalu bahula-vyavastha akaala vruddhaapya ksheenata samalakshanaanni abhivruddhi chesaayi, idhi dna nashtam mariyu vruddhaapya madhya sambandhaanni balopetam chestundi. (vruddhaapyam yokka dna nashtam siddhaantam chudandi).
adavi-rakam elukala jeevitakaalaanni podiginche aahara parimiti, "ersisi5" ("expigy") utparivartana elukala jeevitakaalaanni kooda gananeeyamgaa penchindi. utparivartana elukala aahara parimiti, vruddhaapyaanni alasyam chestunnappudu, janyuvu vistruta dna nashtam perukupovadaanni mandagistundi mariyu transcriptional avutputnu samrakshistundi, tadwara merugaina kana saadhyataku dohadam chestundi.
paraspara charyalu.
ersisi5 ersisi2thoo sankarshana chendutundani choopabadindi.