
cytotrophoblast

"cytotrophoblast" anedi trophoblast yokka lopali pora (langans pora anie kooda pilustaaru) ledhaa akkada nivasinche kanaalu rendintikee ivvabadina paeru. idhi abhivruddhi chendutunna pindamlo synceteotrophoblast lopali bhaagamlo mariyu blastosist godaku velupali bhaagamlo untundi.
cytotrophoblastnu trophoblastic stem selga pariganistaaru, endukante blastosist chuttoo unna pora alaage untundi, ayithe dotter kanaalu vaeru chesi, bahula paatralalo panicheyadaaniki vistaristaayi. cytotrophoblastic kanaalu vaeru cheyagala rendu vamsaalu unnaih fusion mariyu invasive. fusion vamsam synceteotrophoblastoblast istundi mariyu invasive vamsam interstitial cytotrophoblast kanaalanu istundi.
garbhaasayamlo pindam amarchadamlo cytotrophoblastic kanaalu mukhyamaina paatra poeshistaayi.
kalayika vamsam.
eee kalayika maargam dwara rendu ledhaa anthakante ekkuva cytotrophoblastla kalayika dwara anni synceteotrophoblast erpadataayi. eee maargam mukhyamainadi endukante pindam-talli vayuvu marpidi, poeshaka marpidi mariyu roganirodhaka mariyu jeevakriya vidhulalo synceteotrophoblast mukhyamaina paatra poeshistumdi.
oka bhedam laeni cytotrophoblastic muula kanam villus cytotrophoblastga vaeru avutundi, idhi praadhamika corianic villini kaligi untundi, mariyu chivariki villus synceteotrophoblastaglast kalisipotundi. cytotrophoblast nundi synceteotrophoblast erpadatam anedi trophoblastic kanaala yokka antima bheda dasha.
epidermal groth phyaaktar, glucocorticoids mariyu human corianic gonadotropin vanti bahula signalling anuvula dwara cytotrophoblastic kanaala syncitializationnu inn vitro dwara prerepinchavacchu.
aakramanaatmaka vamsam.
invasive vamsam implantation prakriyaloo avasaramaina cytotrophoblastlanu srushtistundi mariyu puurtigaa panichese mavini yerparustundi. oka bhedam laeni cytotrophoblastic muula kanam oka asaadhaaranamaina cytotrophoblast intermediatga mariyu taruvaata oka madhyantara cytotrophoblastga vaeru chestundi. oka madhyantara cytotrophoblast appudu endovascular cytotrophoblastga marinta vaeru cheyavachu ledhaa syncitiumnu yerparustundi.
madhyantara cytotrophoblast.
interstitial cytotrophoblast yokka praadhamika pani perugutunna pindamnu talli garbhasaya kanajaalaaniki langaru veyadam. eee kanaalu mottam endometrium mariyu myometrium yokka sameepa moodava bhagampai daadi cheyavachu.
eee kanaalu deciduva yokka kanaala modati konni porala gundaa chochukupoyina tarvaata, avi vistarinche saamarthyaanni kolpotayi mariyu haanikaramgaa marutayi. kana chakram nundi eee nishkramana tgf-bita mariyu decarine vanti kaarakaala kaaranamgaa unnatlu telustondi. eee invasive interstitial cytotrophoblastlu ikapai vibhajinchalenappatiki, avi syncitianu yerparuchukune saamarthyaanni kaligi untaayi. madhyantara cytotrophoblastla kalayika phalitamgaa bahula-nucleated pedda kanaalu (chinna syncitia) placental bedd mariyu myometriumlo kanipistaayi.
madhyantara cytotrophoblastlu kooda endovascular cytotrophoblastluga maaravacchu.
endovascular cytotrophoblast.
endovascular cytotrophoblast yokka praadhamika pani talli sarpila dhamanulaloki chochukupoyi, perugutunna pindam upayoginchadaaniki maavi gundaa rakta pravahanni daari teeyadam.
avi phenocopy prakriya nundi interstitial cytotrophoblastla nundi utpannamavutaayi. idhi eee kanaala samalakshanaanni epithelial nundi endothelialga maarustundi. endovascular cytotrophoblastlu, vaati puurveekula vale, vyaapti chendanivi mariyu haanikaramainavi.
implantationlo paatra.
blastosist amarchadamlo saraina cytotrophoblast function avasaram. podugutunna taruvaata, blastosist yokka pinda dhruvam garbhasaya endometriyaaniki edurugaa untundi. vaaru taakina tarvaata trophoblast vaegamgaa vistarinchadam praarambhistundi. cytotrophoblast proteolytic enjaimlanu sravistundi, idhi endometrial kanaala madhya extracellular matricksnu vichchinnam chestundi, tadwara trophoblast yokka vaelu lanty anchanaalu chochukupovadaniki veelu kalpistundi. cytotrophoblast mariyu synceteotrophoblast yokka anchanaalu pindaanni endometrial epithelium puurtigaa kappabade varaku endometriumloki laagutaayi, gaddakattadam plug kosam aadaa cheyandi.
anubandha rugmatalu.
atyanta saadhaarana anubandha rugmata prii-eclampsia, idhi mottam jananaalalo sumaru 7 saatam mandini prabhaavitam chestundi. garbhaasayampai mariyu daani vasculaturepy, mukhyamgaa endovascular cytotrophoblast daadi cheyalsina sarpila dhamanulapai daadi cheyadamlo cytotrophoblast vaiphalyam dheeni lakshanam. dheeni phalitamgaa pindaaniki rakta pravaham taggutundi, idhi garbhaasayamlo perugudala parimitiki kaaranam kaavacchu. talliloo prii-eclampsia yokka clinical lakshanaalu saadhaaranamgaa adhika raktapotu, proteinuria mariyu vaapu.
dheeniki viruddhamgaa, trophoblast dwara garbhasaya kanajaalam meeda ekkuva daadi unte, appudu hydatidiform maccha ledhaa choreocarcinoma talettavachhu.