
delorajepam

clardesmethyldiazeppe mariyu nordiclazepam anie kooda piluvabade delarajepam, benzodiazepine mariyu desmethyldiazepam nundi utpannamaina aushadham. idhi italeelo vikrayinchabadutundi, ikkada idhi enn mariyu dadumir anae vaanijya paerutoe andubaatulo undhi. deloragipam (clardesmethyldiaseppagy) kooda benzodiazipine aushadhaalaina diclogypom mariyu cloxazolum yokka kriyaaseela jeevakriya. pratikuula prabhavalalo hangover rakam prabhavalu, magata, pravartanaa balaheenatalu mariyu swalpakaalika ghnaapakasakti balaheenatalu undavacchu. itara benzodiazipines maadirigaane delarajipamlo angiolytic, asthipanjara kandaraala sadalimpu, hypnotic mariyu anticonvalsant lakshanaalu unnaayi.
suuchanalu.
delarajepamnu pradhanamgaa angioliticga upayogistaaru, endukante daani sudeergha tolagimpu sagam-jeevitam; swalpa-natana aushadham lorajepam kante aadhipatyaanni chooputundi. antidepressant mandulu, paraxetine mariyu imipramine thoo poliste, delarajepam swalpakaalikamgaa marinta prabhaavavantamgaa unnatlu kanugonabadindi, conny 4 vaaraala tarvaata antidepressants merugaina yanti-anjoity prabhavalanu choopinchaayi.
delarajepamnu daani angiolytic lakshanaala kosam dantha bhayaniki mundastu aushadhamgaa kooda upayogistaaru. aaa raatri aandolana-sambandhita nidralemi nundi upasamanam kaliginchadaaniki dantha (ledhaa itara vaidya) prakriyaku mundu raatri delorajepam yokka adhika motaadulanu ivvavacchu, aaa prabhavalu marusati roeju aandolanaku taginantagaa chikitsa cheyadaaniki taginanta kaalam konasaagutaayi.
madyam upasamharanaku chikitsa cheyadamlo kooda delarajepam prabhavanni pradarsinchindi.
labhyata.
delorajepam tablet mariyu liquid drop suutreekaranalaloo labhistundi. drava binduvu suutreekarana marinta twaragaa grahinchabadutundi mariyu jeevavaividhyaanni meruguparichindi.
aushadha shaastram.
delorajepam paripalana tarvaata baga grahinchabadutundi, 1-2 gantallo garishta plasma sthaayilaku cherukuntundi. idhi chaalaa sudeergha tolagimpu sagam jeevitaanni kaligi undhi mariyu motaadu teesukunna 72 gantala tarvaata kooda gurtinchavacchu. jeeva labhyata daadaapu 77 saatam undhi. garishta plasma sthaayilu paripalana tarvaata kevalam oka ganta kante ekkuva samayamlo sambhavistaayi. delarajepam yokka nemmadigaa jeevakriya kaaranamgaa gananeeyamaina perukupovadam jarugutundi; vruddhulu delarajepam mariyu daani kriyaaseela jeevakriyanu yuva vyaktula kante nemmadigaa jeevakriya chestaaru, phalitamgaa delarajepam yokka motaadu vaegamgaa perukupotundi mariyu yuva vyaktiki samaana motaadu kante adhika plasma saandratatoe garishta sthaayiki cherutundi. vruddhulu kooda chikitsa prabhaavaalaku paelavamaina pratispandananu mariyu pratikuula prabhaavaala adhika retunu kaligi untaaru. delarajepam yokka tolagimpu sagam jeevitam 80-115 gantalu. delarajepam yokka kriyaaseela jeevakriya lorajepam mariyu idhi maatru aushadham (delarajepam) loe 15-24 saatam praatinidhyam vahistundi. delorajepam yokka pharmacokinetics aahaaramto teesukunte, kontha varaku shoshana mandaginchadam tappa, maarchabadadu. delorazepams shakti daadaapu lorajepam saktiki samanamga untundi, diazepam (1 mg delorajepam = 1 mg lorajepam = 5 mg diazepam) kante baruvutho padhi retlu ekkuva saktivantamainadi, saadhaarana motaadulu 0.5 mg-2 mg varaku untaayi. chikitsa saadhaaranamgaa aarogyakaramaina peddalaku 1 mg vadda mariyu pediatric mariyu geriatric rogulaku mariyu telikapati moothrapindaala balaheenata unna rogulaku 0.5 mg vadda praarambhinchabadutundi, chikitsa mitamaina ledhaa teevramaina moothrapindaala balaheenata unna rogulalo viruddhamgaa untundi.
dushprabhaavaalu mariyu vyatiraeka suuchanalu.
delarajipam gaba positive alosteric modulatorla (itara benzodiazipines maadirigaa) yokka anni classic dushprabhaavaalanu kaligi untundi. veetilo upasamanam/nidralemi, maikamu/ataxia, ghnaanoodayam, taggina nirodham, perigina matlade/saamaajikata, aanandam, balaheenamaina teerpu, bhraantulu mariyu swaasakosha maandyam unnaayi. perigina aandolana, utsaaham mariyu dookudu vanti viruddhamaina praticharyalu sambhavinchavachhu mariyu vruddhulu, pediatric mariyu schizophrenic rogulalo ivi sarvasaadhaaranam. arudaina sandarbhaallo, delarajepam aatmahatya aalochanalu mariyu charyalaku kaaranam kaavacchu.
delarajipam (alaage anni itara benzodiazipines) yokka deerghakaalika upayogam deerghakaalika abhignaa lopaalanu (aarava nela kante ekkuva kaalam konasaagutundi) penchutundani kanugonabadindi, idhi saasvatamani kontamandi parisoedhakulu paerkonnaaru. swalpakaalika upayogam appudappudu niraasaku kaaranam kaavacchu mariyu ekkuva kaalam upayoginchadamto niraasa lakshanaalu sambhavinche pramaadam gananeeyamgaa perugutundi, delorajepamnu appudappudu avasaramaina praatipadikana matrame upayogiste tappa 2 nundi 4 vaaraalaku minchi upayoginchadaaniki uddesinchabadadu. avasaramaina praatipadikana upayoginchinappudu, delorajepam kosam kotta prescription jaarii cheyabadina pratisaaree delorajepam chikitsa avasaranni tirigi anchanaa veyali, mariyu rogulu delorajepamnu alavatuga teesukovadam praarambhistae (varusaga chaalaa rojulu) pratyaamnaaya mandulanu pariganinchaali.
deerghakaalika delorajepam vadakam yokka atyanta teevramaina prabhavam aadharapadatam, upasamharana lakshanaalu delorajepam vadakam nilipiveyabadinappudu kanipinche praksubdha prakampanalanu anukaristaayi. delarajepam nundi upasamharana prabhavalu saadhaaranamgaa daani takkuva-natana gala pratyardhula kante takkuva teevramgaa unnappatikee, avi praanaantakam kaavacchu. upasamharana teevratanu tagginchadaaniki vaaralu ledhaa nelala vyavadhilo delarajepam yokka nemmadigaa dii-titration saadhaaranamgaa suuchimchabadutumdi. tirigi vachhe aandolana mariyu nidralemi vanti upasamharana yokka manasika prabhavalu saareeraka aadharapadataanni vijayavantamgaa chikitsa chesina tarvaata nelala tarabadi konasaagutaayani telisindi.
teevramaina schizophrenia ledhaa skizo-effective desorders unnavaarilo, deloragipam ledhaa sambandhita benzodiazipainlaku allergy ledhaa hypersensitivity unnavaarilo mariyu madhyasta nundi teevramaina moothrapindaala balaheenata unnavaarilo (telikapati moothrapindaala balaheenata unna rogulaku deloragipam konnisaarlu takkuva motaadulo ivvabadutundi) deloragipam vyatiraekamainadi. delarajepam saadhaaranamgaa teevramaina teevramaina ledhaa deerghakaalika anaarogyaalu unna rogulalo vyatiraekamgaa pariganinchabadutundi, ayithe appudappudu vaari chivari rojulu/vaaraala jeevitamlo antima rogula upasamana samrakshanhalo upayogistaaru.
padaardham mariyu/ledhaa madyam vadakam yokka charitra unna rogulaku delarajepam (alaage anni itara benzodiazepines) durviniyogam chese pramaadam ekkuvagaa untundani nammutaaru, atuvanti rogulaku vaidyudu delarajepamnu suuchimchinappudu dheenini pariganinchaali. delorajepamto chikitsa pondutunna rogulandarinee vadakam mariyu mandula mallimpu sankethaala kosam mamuluga paryaveekshinchaalsinapti, padaartham mariyu/ledhaa madyam vadakam yokka charitra unna rogula paryaveekshanhanu penchadam ellappuduu avasaram. deerghakaalika/vakreebhavana aandolana, nidralemi mariyu adapadadapa kandaraala timmiri kosam avasaramaina praatipadikana suuchimchina rogulalo vaidyetara benzodiazipine vadakam sambhavinchindi mariyu saadhaaranamgaa chaalaa nemmadigaa sambhavistundi, chikitsa praarambhinchina nelalu ledhaa samvatsaraala tarvaata matrame spashtamgaa kanipistundi. chaalaa nelalu ledhaa samvatsaraalugaa rogulu mandulapai sthiramgaa unnappatikee delarajepamnu churukuga upayogistunna rogula paryaveekshanhanu eppatikee nilipiveyavaddu.
itara upasamana mandulatho paatu delorajepamnu icchinappudu jaagratta vahinchaali (udhaa. upasamanam, ataxia mariyu (praanaantakamaina) swaasakosha maandyam pramaadaanni penchadam valla opiates, barbiturates, jedd-drugs mariyu phenotheogenes). benzodiazipines yokka adhika motaadu arudugaa maranaaniki daariteesinappatikee, benzodiazipines mariyu itara mattumandula kalayika (mukhyamgaa barbituratelu mariyu alkahal vanti itara gabbaminergic mandulu) maranaaniki daariteese avakaasam chaalaa ekkuva.
pratyeka heccharikalu.
hemodialysis loe moothrapindaala vaiphalyam unna vyaktulu nemmadigaa tolagimpu raetu mariyu aushadham yokka pampinhee taggutundi. kaaleya vyaadhi delorajepam tolagimpu retupai teevra prabhavanni chooputundi, phalitamgaa sagam jeevitam daadaapu rettimpu ayi 395 gantalu avutundi, ayithe aarogyakaramaina rogulu sagatuna 204 gantala tolagimpu sagam jeevitaanni chuupimchaaru. kaaleya vyaadhi unna rogulalo delorajepamnu upayoginchetappudu jaagratta vahinchaalani sifaarsu cheyabadindi.

