
mcm10

protein mcm10 homolog anedi maanavulalo "mcm10" janyuvu dwara encode cheyabadina protein. idhi cdc45: mcm2-7: gins helicase yokka kriyaaseelataku avasaram, anduvalla saraina DNA pratiruupanaku avasaram.
function.
eee janyuvu dwara encode cheyabadina protein anedi eucariotic genome replication praarambhamlo palgone atyanta samrakshinchabadina minee-chromosome maintenance proteinlalo (mcm) okati. mcm proteinla dwara erpadina protein complexes anedi prii-replication complexes (prii-arsi) loe keelaka bhaagam mariyu idhi replication forkula erpadatamlo mariyu itara dna replication sambandhita proteinla niyaamakamlo paalgonavacchu. eee protein mcm2 mariyu mcm6 thoo, alaage muulam gurtimpu protein arsi2 thoo sankarshana chendagaladu. idhi proteolysis mariyu sell saikil-aadhaarita paddhatiloo phosphorylation dwara niyantrinchabadutundi. genopaslo ilanti protein yokka adhyayanalu dna replication praarambhamlo eee protein yokka chromatin binding prii-arsi assembly tarvaata mariyu muulam vipputaku mundu anie suuchistunnaayi. vibhina isopharmlanu encoding chese pratyamnaayamgaa spliesed transcript vaeriyantlu gurtinchabaddaayi.
paraspara charyalu.
mcm10 anedi orsi2ell thoo sankarshana chendutundani choopabadindi.

