
foyal immuno deficiency syndrome

modata phaal poney syndrome anie piluvabade foyal immuno deficiency syndrome (phis) pradhanamgaa rendu jaatula gurralanu prabhaavitam chestundih phaal mariyu dales. phis anedi tirogamana janyu vyaadhi. prabhaavitamaina pandhi janana samayamlo saadhaaranamgaa kanipistaayi, conny balaheenamgaa marutayi, mariyu roganirodhaka shakti lopam valla kalige nirantara antuvyaadhula kaaranamgaa moodu nelala vayassulo chanipotayi ledhaa anayasa cheyabadataayi.
lakshanaalu.
prabhaavitamaina pandhi pillalu puttinapudu aarogyamgaa untaayi. oka nela vayassu vachesariki, pandhi maandyam chendutaayi, baruvu taggutaayi, virechanaalu mariyu nasika sraavam thoo daggunu kaligi untaayi. chikitsaku pratispandanagaa atisaaram mariyu daggu modatlo merugupadataayi, conny chikitsa asamarthamgaa maaradamtho marinta digajaarutaayi. pandhi kotu podigaa mariyu chuustuu untundi mariyu pandhi peelchukovadamlo viphalamainanduna rendu nelala vayassulo pandhi marinta balaheenapadutundi, mariyu 3 nelala vayassulo, pandhi maranistundi (ledhaa anayasa cheyabadutundi), eee vyaadhiki 100% maranaala retunu istundi.
janyusaastram.
phis anedi tirogamana janyu vyaadhi; prabhaavita rekula prabhaavita janyuvuku sajaateeyamgaa untaayi, antey, avi janyuvu yokka rendu kaapeelanu kaligi untaayi, prati parent nundi vaarasatvamgaa vacchina oka coppy. idhi jaragalante, tallidandrulu iddaroo janyuvu yokka vahakalu ayi undaali. 2010loe, 39 saatam padipoyina gurrapu pandulu mariyu 18 saatam dales gurrapu pandulu santaanotpattiki mundu pareekshinchina prabhaavita janyuvunu kaligi unnaayi. eee mutation manalo sumaru 9 saatam mariyu european gypsy gurraalalo kooda kanipistundi.
sodiyam/mayo-innocital cottransporter (slc5eah3) janyuvulo oke nucleotide polymorphism (mutation), phis kuu kaaranamavutundi. dravaabhisarana ottidiki kana pratispandananu niyantrinchadamlo eee janyuvu keelakam; janyuvu yokka paniteerulo maarpu erra rakta kanaala utpatti (erythropoisis) vaiphalyam mariyu roganirodhaka vyavastha vaiphalyaaniki daariteestundi.
rooga nirdhaarana mariyu chikitsa.
janyu pareeksha valla pandhi pilliki phis undaa ledhaa anedi telustundi. pandhi abhivruddhi chendutunna infectionlaku samarthavanthamaina chikitsa ledhu; anayasa anedi ishtapade empika.
charitra.
eee vyaadhi modatisaarigaa 1996loe nivedinchabadindi. modati kesulu padipoyina gurrapu pillulaloo kanugonabaddayi, mariyu eee vyaadhini modatlo "padipoyina gurrapu gurrapu syndrome" anie pilicheevaaru."eee vyaadhi oka janyu bhaganni kaligi unnatlu kanipinchindi, mariyu itara gurrapu jaatulanu prabhaavitam chese vamsapaaramparya vyaadhulanu parisoedhimchina taruvaata, idhi kottagaa gurtinchina vyaadhi anie nirdhaarinchabadindi. janyuvu-vistruta anubandha adhyayananni upayoginchi vyaadhiki kaaranaanni kanugonnaru, idhi gurrapu chromosome 25paie oka praantaanni suuchimchimdi. eee chromosome aidu prabhaavita gurraalalo kramabaddheekarinchabadindi, mariyu 2009loe, slc5eah3 janyuvulo oka utparivartana kanugonabadindi. dheeni taruvaata koddikaalaanike, gurrapu yajamaanulu vaari gurrapu gurralu vahakalu kaadaa anie gurtinchadaaniki janyu pareekshanu praarambhinchaaru.
drukpatham.
prabhaavitamaina padipoyina mariyu dales gurrapu pandula jaatulaku, sambhogaaniki mundu gurrapu pandula janyu pareeksha vahakalu eppuduu kalisi undavani nirdhaaristundi, idhi prabhaavitamaina pandhi pillalu puttakunda nirodhistundi. kalakramena, gurrapu pandula janyu vaividhyampai pratikuula prabhavam chupakunda, vyaadhi janyuvu yokka tarachudanam taggutundi.

