
vaarasatvamgaa vacchina thrombotic thrombocytopenic parpura

thrombotic thrombocytopenic parpura (ttp) anedi praanaantakamaina rugmata, idhi thrombocytopenia mariyu microngiopathic haemolitic raktaheenatato paatu variable neurological disfunction, moothrapindaala vaiphalyam mariyu jwaramtho untundi. idhi vaan willebrand phyaaktar-cleaving protease adams 13 yokka karyakalapalu teevramgaa taggadam valla sambhavistundi. "adams 13" janyu utparivartanala valla kalige vamsapaaramparya ttp chaalaa takkuvagaa untundi.
puttukatho vacchina ledhaa vaarasatvamgaa vacchina ttp ttp yokka anni kesulalo 5 saatam kante takkuvagaa untundi mariyu vaarshika sambhavam 1/1,000,000 kante takkuvagaa anchanaa veyabadindi. vamsapaaramparya ttp unna kutumbaalalo 80 kante ekkuva vibhina utparivartanalu gurtinchabaddaayi.chaalaa mandhi rogulu mishrama bhinnamaina utparivartanaalaku vahakalu. audamts 13" looni exon 23loe nucleotides 2930-2935 yokka homozygus tholagimputho sahaa, homozygus roopamlo 15 utparivartanalu matrame gamaninchabaddaayi.

