
deodenase

deodenase (ledhaa "monodiodiness") anedi thyroid harmonela kriyaaseelata ledhaa nishkriyaatmakatalo palgone peroxidase enjaim.
rakalu.
diodinesses rakaalalo ivi unnaih
iodothyronine diodinesses neerugaa thyronine harmonela nundi iodine vidudalanu utprerakam chestaayi. avi peroxyredoxins (prx) nuu pooli unde utpreraka domaintho selenosystein-aadhaarita pora proteins. moodu sambandhita isopharmlu, deodenase rakam i, ii, mariyu iii, lakshya kanaalalo praarambhamlo vidudala chesina harmon puurvagaami t4 (thyroxine) nuu t3 (triodothyronine) ledhaa rt3 (riverse triodothyronine) loki sakriyam cheyadaaniki mariyu nishkriyam cheyadaaniki dohadam chestaayi. enjaimlu iodine yokka tagginche tolagimpunu utprerakam chestaayi (vividha isopharmlu vividha thyronine sthaanaalapai daadi chestaayi), tadwara tamanu taamu prix maadirigaane aakseekarinchukuntaayi, taruvaata enjaim yokka tagginche recycling jarugutundi.
iodotyrosine deodenase thyroid harmonela vichchinnaaniki dohadam chestundi. idhi iodothyronins yokka catabolism phalitamgaa iodenated tyrosinla nundi punaruddharinchabadina upayogam kosam ayodinnu vidudala chestundi. iodotyrosine deodenase oka flavin mononucleotide cofactornu upayogistundi mariyu idhi naad oxidase/flavin reductase suupar famileaki chendinadi.
aakali pratispandana.
aakali ledhaa teevramaina ottidilo, deodenase rakam 1 nirodhinchabadutundi, idhi t3 yokka prasarana sthaayilanu taggistundi (idhi plasmalo t4 nundi paridheeyamgaa marchabadina t3 yokka pradhana muulam kavadam valla), idhi jeevakriya retulo taggudalaku kaaranamavutundi. sahajamgaane, t3 yokka plasma sthaayilu padipothe, tsh loe parihara perugudala untundi, dheeni sraavam t3 dwara nirodhinchabadutundi. ayithe, type 2 deodenase petutory mariyu cn laloe t4 nundi t3 gaa maaradaaniki madhyavartitvam chestundi, mariyu kelareela parimiti eee enjaimnu prabhaavitam cheyadu kabatti, pityootareelo sthaanika t3 sthaayilu saadhaaranam.anduvalla, pityuutariilooni thyrotrophes (pityootareelo endocrine kanaalu) taginanta mottamlo tii3 kaligi untaayi, mariyu tshech loe etuvanti parihara perugudala jaragadu.
kelareela parimiti yokka eee prabhavam aakalitho unna vyaktiki ardhame endukante idhi sareeramlo indhana nilvalanu samrakshistundi. marovaipu, eee prabhavam aaharam teesukune samayamlo uddeshapoorvakamgaa baruvu taggadam marinta kashtataram chestundi.
selenium.
selenosystein gaa iodothyronine deodenase loe selenium, tii3 yokka uchita prasarana sthaayilanu nirnayinchadamlo keelaka paatra poeshistumdi. selenium lopam tii3 sthaayila pathanamlo chikkulanu kaligi untundi.