
pratikuula sanghatanalaku saadhaarana paribhasha pramaanaalu

gatamlo saadhaarana vishapuurita pramaanaalu (citisi ledhaa nci-sisi) anie piluvabade pratikuula sanghatanalaku saadhaarana padajaala pramaanaalu (ctcae), cancer chikitsalo upayoginche aushadhaala pratikuula prabhaavaala praamaanika vargeekaranaku pramaanaala samiti. 
ctcae vyavastha anedi yuu. ess. national cancer institute (nci) yokka utpatti.
modati punaraavrutam 1998 kii mundu jarigindi. 1999 loe, FDA 2010 loe y version 4 kii naveekaranatho 2009 loe version 2. ctcae version 4 nuu vidudala chesindi. prastuta version 5 november 27,2017 naa vidudala cheyabadindi. aneka clinical trials, ippudu oncologyki minchi vistarinchaayi, ctcae vyavastha aadhaaramgaa vaari pariseelanalanu encode chestaayi.
idhi 1 nundi 5 varaku shrenula shrenini upayogistundi. nirdishta paristhitulu mariyu lakshanaalu prati sthaayiki viluvalu ledhaa vivaranaatmaka vyakhyanu kaligi undavacchu, conny saadhaarana maargadarsakam emitante 
grade 1: telikapati, lakshanarahita lakshanaalugaa nirvachinchabadindi. clinical ledhaa diagnostic pariseelanalu matrame; jokyam soochinchabadaledu.
grade 2: mitamainadi; kaneesa, sthaanika ledhaa naan-invasive jokyam avasaram.
grade 3: teevramaina lakshanaalu ledhaa vaidyaparamgaa mukhyamainavi conny praanaantakam kaadu conny ADL loe sweeya samrakshananu nilipiveyadam ledhaa parimitam cheyadam kaavacchu
grade 4: praanaantaka parinaamaalu; atyavasara ledhaa atyavasara jokyam avasaram
grade 5: pratikuula sanghatanaku sambandhinchina ledhaa kaaranamgaa maranam

