ell-jailyuloj reductase

carbonyl reductase II anie kooda piluvabade dicarbonyl/ell-xylulose reductase, chromosome 17 loe unna dii. sii. ex. aarr janyuvu dwara maanavulalo encode cheyabadina enjaim.
nirmaanam.
dcxr janyuvu sumaru 34 kda parimaanamlo mariyu 224 amaino aamlaalatoe kuudina pora proteinnu encode chestundi. protein moothrapindamlo ekkuvagaa vyakteekarinchabadutundi mariyu cytoplasmic poraku sthaanikeekaristundi.
function.
dii. sii. ess. aarr. aneka ell-oxylose taggimputoe paatu aneka pentoges, tetros, triges, alfa-dicarbonyl sammelanaalanu utprerakam chestundi. enjaim carbohydrate metabolism, glucose metabolism, euronate saikil loe paalgontundi mariyu xylitol nuu utpatti cheyadam dwara sameepa moothrapindaala gottaalalo neeti shoshana mariyu cellular osmorgulationlo paatra poeshistumdi.
enjaimologylo, ell-jailyuloj reductase () anedi rasayana praticharyanu utprerakam chese enjaim.
anduvalla, eee enjaim yokka rendu uparitalaalu xylitol mariyu nadp +, ayithe daani 3 utpattulu l-xylulose, nadph mariyu h +.
eee enjaim short-chain oxidoreductasela suupar famileaki chendinadi, pratyaekamgaa daata yokka ch-oh samuuhampai nad + ledhaa nadp + thoo sweekartagaa panichesevi. eee enjaim taragati yokka kramabaddhamaina paeru xylitol: nadp + 2-oxidoreductase (l-xyulose-forming).
clinical praamukhyata.
pentosuriaku lopam kaaranamavutundi. ell-jailyuloj reductage charya yokka lopam anedi ell-jailyuloj yokka adhika moothra visarjana dwara vargeekarinchabadina jeevakriya vyaadhi yokka puttukatho vacchina lopaniki kaaranamavutundi.
protein yokka athi-vyakteekarana mariyu ectopic vyakteekarana prostate adenocarcinomatho mudipadi undavacchu.

