boeckelheid praticharya

boeckelheid praticharya anedi α-picolin-"n"-oxidelanu hydroxymethylpyridine punarvyavastheekarinchadam. punarvyavastheekarinchadam dheenini modatisaarigaa nivedinchina virgil boeckelheid paeru meeda dheeniki paeru pettaru. vaastavaaniki eee praticharya acetic unhydride upayoginchi jarigindi, dheeniki saadhaaranamgaa refluxes (~ 140 masim) vadda oka kaalam avasaram. triphluoroacetic unhydride (tfaa) nuu upayoginchi praticharyanu nirvahinchavacchu, idhi tarachugaa gadhi ushnograta praticharyaku anumatistundi.
yantraangam.
boeckelheid praticharya yokka vidhanam triphluoroacetic unhydride nundi "enn"-oxide oxygennu acl badilee cheyadam dwara praarambhamavutundi. α-methyl carbon appudu trifluoroacetate ayan dwara deprotonate cheyabadutundi. idhi anuvunu trifluoroacetylated methyl pyridine nuu andinche [3]-sigmatropic punarvyavastheekarana kosam amarchutundi. trifluoro acetate yokka jalavisleshana hydroxymethylpyridine nuu vidudala chestundi.

