
cresentine

cresentine anedi eucariotic kanaalalo kanipinche madhyantara tantuvulaku sambandhinchina bacteria sambandhita protein. tubulinlu mariyu actinlu, itara pradhana cytoskelital proteins, varusaga procariotic homolaglanu kaligi unnatle, eff tii ess jedd mariyu mreb proteins, madhyantara tantuvulu cresentine proteintho mudipadi untaayi. daani konni homolaglu chromosome segregation protein paaraa anie tappugaa label cheyabaddaayi. eee protein kutumbam "calobacter" mariyu "methylobacterium" loe kanipistundi.
kana aakaaramlo paatra.
cresentinnu 2009loe christin jacobs-wagner "calobacter cresentus" (ippudu "vibrioids") loe kanugonnaru, idhi oka jala bacteria, idhi daani cressent aakarapu kanaalanu merugaina chalanasheelata kosam upayogistundi. cresentine protein eee kanaala putaakaara mukhampai untundi mariyu protein laeni utparivartanaalu raad aakarapu kanaalanu yerparustaayi kabatti vaati akaaraaniki avasaramainatluga kanipistundi. calobacter" kanaala aakaraanni prabhaavitam cheyadaaniki, cresentine tantuvula helix kanaaniki oka parshwa bhaagamlo kana pora yokka cytoplasmic vaiputho anubandhinchabadataayi. idhi chinna kanaalalo vakra kana aakaraanni prerepistundi, ivi cresentine yokka helical pitch kante takkuvagaa untaayi, conny paatha, podavaina kanaalalo suruli aakaraanni prerepistaayi.
protein nirmaanam.
eucariotic intermediate philaments maadirigaane, cresentine philamentsga vyavastheekarinchabadutundi mariyu kanamlo oka helical nirmaanamloo untundi. calobacter" procariot (vibroid/cressent-aakaram mariyu helical aakaram, idhi sudeergha sthira dasha tarvaata sweekarinchavachhu) yokka rendu aakaaraalaku cresentn avasaram. cresentine proteinlo 430 avasheshaalu untaayi; daani kramam ekkuvagaa 7 punaraavruta avasheshaala namuunaanu kaligi untundi, ivi kaayil-kaayil nirmaanaanni yerparustaayi. protein yokka dna kramam eucariotic keratin mariyu lamin proteinlatho chaalaa pooli unde vibhaagaalanu kaligi untundi, ekkuvagaa kaayil-kaayil nirmaanaanni kaligi untundi. parisoedhakulu ausmi mariyu itarulu. jantuvula madhyantara tantuvu proteinla maadirigaane, cresentine naalugu kaayil-kaayil vibhaagaalato kuudina kendra raadnu kaligi undani iteevala niroopinchabadindi. madhyantara tantuvu mariyu cresentine proteins rendoo naalugu α-helical vibhaagaalato paatu naan-α-helical linker domainlatho sahaa praathamika kramaanni kaligi untaayi. cresentine mariyu janthu madhyantara filament proteinla madhya oka mukhyamaina vyatyaasam emitante, cresentine raad domine chivarlalo konni ekaabhipraaya kramam muulakaalanu kaligi undadu, ivi janthu lamin mariyu keratin proteinlalo samrakshinchabadataayi.
protein eucariotic iff proteinla maadirigaane vyavastheekrutamaina konni upa domainlugaa vibhajinchabadindi. prati parisoedhakudu idhi madhyantara tantuvula yokka homolog anie nammaru, badulugaa eee saaruupyata convergent evalution dwara udbhavinchi undavacchani suuchistumdi.
tantuvula assembly.
eucariotic intermediate filament proteins shakti input avasaram lekunda sell lopala 8-15 nm yokka philamentlaloki sameekaristaayi, antey, ATP ledhaa GTP avasaram ledhu. ousmis mariyu itarulu. eee vidhamgaa "inn vitro" loe protein tantuvulugaa sameekarinchagaladaa anie pareekshinchadam dwara vaari cresentine parisoedhananu konasaaginchaaru. cresentine proteins nijamgaa 10 nm vedalpu gala tantuvulanu yerparuchukunnayani, eucariotic intermediate tantuvula maadirigaane eee tantuvulalo konni pakkaki kattaluga vyavastheekarinchabadi unnayani vaaru kanugonnaru. madhyantara tantuvu proteinlatho cresentine protein yokka saaruupyata eee rendu cytoskelital proteinla madhya parinaamaatmaka sambandhaanni suuchistumdi.
eucariotic intermediate philaments maadirigaane, cresentine nundi nirminchina filament saagedi. vyaktigata proteins nemmadigaa vidipotaayi, deenivalla nirmaanam kontha gattiga mariyu nemmadigaa punarnirminchabadutundi. eucariotic ifs maadirigaa kakunda, strain nirmaanam gattipadataaniki prerepinchadu.

