
upabhasha paripalana

latin nundi "naaluka kinda" kosam upabhasha (sankshiptamgaa sl), aushadha nirvahana marganni suuchistumdi, dheeni dwara padaarthaalu naaluka kinda kanajaalaala dwara raktamloki vyaapistaayi.
hridayanaala mandulu, steroidlu, barbituratelu, benzodiazipines, opioid analgesics, tihechsi, cbd, konni proteins mariyu perugutunna vitaminlu mariyu khanijaalato sahaa aneka mandulu upabhasha paripalana dwara grahinchabadataayi.
suutram.
oka rasayanamu naaluka krinda unna shleshma poratho sambandham vachinappudu, adhi grahinchabadutundi. epithelium krinda unna bandhana kanajaalam kesanaalikalanu samruddhiga kaligi untundi kabatti, aaa padaardham vaatiloki vyaapinchi sirala prasaranaloki pravesistundi. dheeniki viruddhamgaa, pregulalo soshinchabadina padaarthaalu saadhaarana prasaranaloki pravesinche mundu kaaleyamlo modati-paas jeevakriyaku lobadi untaayi.
moukhika paripalana kante upabhasha paripalanaku konni prayojanaalu unnaayi. marinta pratyakshamgaa undatam valla, idhi tarachugaa charyanu vaegamgaa praarambhistundi, mariyu idhi raktapravaahamloki pravesinche mundu lalajala enjaimla dwara matrame padaardham ksheenataku gurayye pramaadaanni nirdhaaristundi, ayithe noti dwara ichhe mandulu jeernasayaantara pregu yokka pratikuula vaataavaranam gundaa vellaali, idhi kadupu aamlam ledhaa pittam dwara ledhaa monoamine accidase (maavo) vanti enjaimla dwara ksheenataku gurayye pramaadam undhi. inca, jeernasayaantara pregu nundi shoshana tarvaata, atuvanti mandulu kaaleyaaniki vellaali, akkada vaatini vistrutamgaa maarchavacchu; dheenini aushadha jeevakriya yokka modati paas prabhavam anie pilustaaru. kadupu mariyu pregula jeernakriya kaaranamgaa, salvinorin eah vanti konni padaarthaalaku noti maargam saripodu.
roopaalu.
upabhasha paripalana kosam aushadha tayaareelu eee krindi roopamlo tayaaru cheyabadataayih
padaartham.
lalajalamlo sulabhamgaa karigipothe daadaapu yea rakamaina padaardham ayina upabhasha paripalanaku anukuulamgaa untundi. podlu mariyu aerosols annee eee paddhatini sadviniyogam chesukovacchu. ayithe, pihech, paramaanu baruvu mariyu lipid draavaneeyata vanti aneka amsaalu maargam aacharanaatmakamainadaa anie nirnayinchavacchu. eee lakshanaala aadhaaramgaa, tagina vidhamgaa karige aushadham shleshmam dwara chaalaa nemmadigaa vyaapinchi prabhaavavantamgaa undavacchu. ayithe, aneka mandulu upabhaashalo teesukovadam chaalaa saktivantamainadi, mariyu idhi saadhaaranamgaa nasika shleshmam dwara ivvadam kante surakshitamaina pratyaamnaayam. eee paddhatini konni psychoactive aushadhaalanu andinche vyaktulu kooda vistrutamgaa upayogistaaru. ayithe, oka lopam emitante, eee paddhatini aamla ledhaa castic mandulu mariyu puurakaalatoe deerghakaalikamgaa upayoginchadam valla dantaala rangu maaradam mariyu kshayam.
psychoactives.
salvinorin eah thoo paatu, itara psychoactives nuu kooda upabhaashalo vartimpajeyavachu. lsd, mdma, marphin, alprajolam, clonazepum, diazipam mariyu cycadelic tryptaminelu mariyu fenethylaminelu mariyu vinoda ganjai tinadaginavi (tihechsi) vanti aneka itara padaarthaalu kooda eee maargam dwara paripalanaku aacharaneeyamainavi. chaalaa tarachugaa, prasnalooni aushadham podigaa chesi notilo unchabadutundi (tarachugaa neerugaa naaluka kinda). akkada ekkuvasepu unchinatlayithe, aaa aushadham zii. ii. marganni daatavesi raktapravaahamloki vyaapistundi. idhi saadhaarana noti paripalana kante ishtapade paddhati kaavacchu, endukante maavo aneka aushadhaalanu (mukhyamgaa dmt vanti tryptaminelu) aakseekarana chestundi mariyu eee maargam rasayananni neerugaa medaduku anuvadistundi, ikkada chaalaa psychoactives panicheestaayi. rasayananni gontulo kadagadam dwara adhika lalajalam dwara eee paddhati parimitam cheyabadutundi. alaage, aneka aalkalaaydlu asahyakaramaina ruchini kaligi untaayi, idhi vaatini notilo pattukovadam kashtataram chestundi. psychoactive pharmaceuticals maatralalo saadhaaranamgaa durviniyogaanni nirutsaahaparachadaaniki mariyu pillalu vaatini tinakunda nirutsaahaparachadaaniki denatonium vanti chedhu rasayanalu untaayi.
allergy kaarakaala.
allergy karakalu kooda allergy immunotherapylo bhaagamgaa naaluka kinda vartinchavachhu.
chikitsa peptides mariyu proteins.
chikitsa peptides mariyu proteinla (cytokins, domine antibodies, fab sakalaalu ledhaa single chain antibodies vantivi) paripalanaku saapekshamgaa kotta maargam upabhasha paripalana. peptides mariyu proteins jeerna-pregula maargamlo sthiramgaa undavu, pradhanamgaa enjaimlu mariyu pihech vyatyaasaala dwara ksheenata kaaranamgaa. paryavasanamga, chaalaa peptides (insulin, exenatide, vasopressin modalainavi).) ledhaa proteins (interferon, epo mariyu interleukins vantivi) injection dwara ivvali. iteevala, kotta saanketikatalu atuvanti anuvula upabhasha nirvahananu anumatinchaayi. novo nordisk, sanofi mariyu biolingus vanti companylu upabhasha maargam dwara macromalicules (peptides, proteins mariyu immunotherapylu) nuu andinchadaaniki prayatnaalu jarugutunnaayi.
sublingual praantaaniki daggaragaa roganirodhaka-grahaka kanaalu undatam valla, sublingual delivery roganirodhaka-kriyaaseela aushadhaalaku mukhyamgaa prabhaavavantamgaa undavacchu.
teekaalu.
vividha antu vyaadhulaku vyatiraekamgaa teekaalu vaeyadaaniki kooda upabhasha marganni upayoginchavacchu. anduvalla, preclinical adhyayanalu sublingual teekaalu atyanta roganirodhaka saktini kaligi untaayani mariyu influenzae virus nundi rakshinchagalavani kanugonnayi.
mariyu "helicobacter pailori", conny itara antu vyaadhulaku vyatiraekamgaa teekaala kosam upabhasha paripalananu kooda upayoginchavacchu.

