
pratyaekamaina padaardhaala gurtimpu

pratyaekamaina padaardhaala gurtimpu (yooni) anedi oka padaardham yokka paramaanu nirmaanam ledhaa vivaranaatmaka samaachaaramtho anusandhaaninchabadina alphanumeric gurtimpu, idhi aaharam mariyu aushadha nirvahana (fda) yokka prapancha padaardhaala namodu vyavastha (gsrs) dwara utpatti cheyabadutundi. idhi rasayana, protein, nucleic aamlam, polymer, nirmanatmakamga vaividhyamaina ledhaa mishrama padaarthaalugaa vargeekaristundi, iso 11238 mariyu iso dts 19844 loe praamaaneekarana kosam antarjaateeya samstha vivarinchina pramaanaala prakaram. unis yajamanya rahitamainavi, pratyekamainavi, spashtamainavi mariyu utpatti cheyadaaniki mariyu upayoginchadaaniki uchitam. oka anuvu nundi oka jeevi varaku edainaa padaarthaanni cherchenta visaalamgaa undi, sanklishtata yea sthaayiloonainaa padaarthaala kosam oka yooni utpatti cheyavachu."
aushadham mariyu jeeva utpattulaloni padaarthaalu vanti niyantrita utpattulaloni padaarthaalaku shaashwata, pratyaekamaina gurtimpulanu utpatti cheyadaaniki gsrs upayoginchabadutundi. gsrs paramaanu nirmaanam, protein mariyu nucleic sequencelu mariyu vivaranaatmaka samacharanni unitini roopondinchadaaniki upayogistundi. oka rasayana padaardhaanni nirvachinchadaaniki ishtapade maargam daani dvi-miteeya paramaanu nirmaanam dwara untundi, endukante idhi oka padaardham yokka gurtimpuku sambandhinchinadi mariyu oka padaardham yokka stereochemistrici sambandhinchina samacharam takshaname andubaatulo untundi. nucleic aamlalu vaati shrenula dwara mariyu unna evaina maarpula dwara nirvachinchabadataayi. proteinla vishayamlo, kaaryaacharanaku avasaramaina itara maarpulatoe paatu, tudi-samuuha maarpulu matrame pratyaekamgaa gurtinchabadataayi. proteinla swaabhaavika binna swabhaavam dheeniki kaaranam. anduvalla, rendu ververu protein padaarthaalu oke unitini panchukogalavu mariyu inca biosemilarity ledhaa chikitsa samaanatvaanni kaligi undavu. polymerlu vaati nirmaanaatmaka punaraavruta unitlu mariyu paramaanu baruvu ledhaa paramaanu baruvuku sambandhinchina lakshanaalu (udhaa.zii. snigdhata). nirmanatmakamga vibhina padaarthaalu anevi sahaja padaarthaalaina mokkala saram mariyu teekaalu nundi sahajamgaa bhinnamaina tayaareelu.
gsrs anedi fda, national center pharr advanced translational sciences (enn cats) mariyu european medicines agency (ema) madhya sahakaram dwara andinchabade uchita pampinhee cheyagala software vyavastha. aushadha utpatti (ii. dii. emm. pii) pramaanaala yokka pradhana ii. ess. oo gurtimpu pramaanaalalo okataina ii. ess. oo 11238 pramaanaanni amalu cheyadaaniki zii. ess. aarr. ess. abhivruddhi cheyabadindi. gsrsnu nirvahinche gsrs bordulo fda, european regulatory agencylu mariyu united states pharmacopia (usp) nipunulu unnaaru.