
neuroangiogenesis

neuroangiogenesis anedi naraalu mariyu rakta naalaala samanvaya perugudala. naadii mariyu raktanaala vyavasthalu maargadarsaka suuchanalanu mariyu kana-uparitala grahakalanu panchukuntaayi, ivi eee samakaaleekarinchina perugudalanu anumatistaayi. neuroangiogenesis" anae padam 2002loe matrame upayogamloki vachindi mariyu eee prakriyanu gatamlo neurovascular patterning anie pilicheevaaru. neurogenesis mariyu angiogenesis kalayika pindam abhivruddhi mariyu prarambha jeevitamlo mukhyamaina bhaagam. endometriosis, medadu kanitulu mariyu algimers vyaadhi vanti vyaadhulalo idhi paatra pooshistundani bhaavistunnaaru.
sareeradharma shaastram.
neurovascular namuunaa.
neurovascular development anedi pindajanya utpatti mariyu prarambha jeevita kaalamlo naadii vyavastha mariyu vascular vyavastha yokka samaantara aavirbhavam mariyu namuunaa. neurovascular congruencini oxon maargadarshakatvamto kuudina bhaagaswaamya paramaanu namuunaa yantraangam dwara nirnayinchinatlu kanipistundi, indulo sema3eah (semaphorine 3eah) mariyu (neuropylene) vanti akshatantu maargadarsaka anuvulu untaayi.
yantraamgaalu.
neuroangeogenic mariyu oxonal maargadarsaka anuvulu perugudalaku maarganirdesam cheyadaaniki neuronal perugudala sankuvulu mariyu endothelial kona kanaalu rendintipai panicheestaayi.
naraala perugudala sankuvulu naraala kanaala konalapai untaayi mariyu saanukuula mariyu pratikuulamaina vividha kaarakaalaku pratispandistaayi. neuron perugudala actin (chitramlo erupu) mariyu microtuble (chitramlo aakupaccha) cytoskeleton podigimpu dwara jarugutundi.
abhivruddhi chendutunna raktanaalaala chivarana kanipinche kona kanaalu neerugaa perugudalanu niyantrinchadaaniki prakkane unna endothelial kanaalanu niyantristaayi. tudi kanaalu grahakaalu mariyu ligandlanu kaligi untaayi, veeti dwara avi sthaanika neuroangeogenic kaarakaalaku pratispandistaayi.
neurogenic karakalu.
aneka neuroangeogenic karakalu unnaayi, veetilo konni neuronal perugudalanu prothsahinchadaaniki panicheestaayi mariyu dheeniki viruddhamgaa panicheestaayi. pattika udaaharanalanu chooputundi
pathology.
neuroangiogenesis anedi endometriosis, medadu kanitulu mariyu algimers vyaadhi vanti vruddhaapya chittavaikalyam vanti aneka vyaadhulalo chikkukundi. veetilo prati okkati aarogya samrakshana parisramaku gananeeyamaina vyayaanni kaligistundi, antey kriyaatmaka chikitsala abhivruddhini praarambhinchadaaniki neuroangiogenesisto sahaa-palgonna prakriyala gurinchi puurti avagahana avasaram.
endometriosis.
endometriosis anedi garbhasayam velupala endometrial kanajaalam amarchadam valla kalige oka saadhaarana stree jananendri vyaadhi, dheeniki deerghakaalika kati noppi oka lakshanam. eee implantla nirmaanam, perugudala mariyu sthirathvam rakta naalaala sarafaraanu penchadaaniki angiogenesis meeda aadharapadi untaayi. phalitamgaa rakta pravaahamlo perugudala noppi lakshanaalatoo neerugaa sambandham kaligi undavacchu. neuroangiogenesis dwara rakta naalaalatoe paatu eee praantaalalo neuronla ekakaala perugudala dheeniki oka saadhyamaina vivarana.
medadu kanitulu.
glioblastoma multiform vanti medadu kanitulu, prongiogenic karakalu, vez mariyu interleukin 8 yokka adhika vyakteekaranhatho sambandham unna dattamaina raktanaalaala dwara vargeekarinchabadataayi.
medaduku gaayam.
ischemic stroke ledhaa baadhaakaramaina medadu gaayam taruvaata, gayapadina kanajaalaaniki oxygen mariyu poeshakaalanu tirigi sarafara cheyadaaniki angiogenesis maddatu istundi mariyu neurogenesis mariyu synaptogenesisnu prerepistundi, mukhyamgaa ischemic penambraalo. neuroangiogenesis chakkaga niyantrinchabadutundi mariyu kramaanugatamgaa untundi, indulo rakta-medadu avarodha paniteerunu punaruddharinchadaaniki endothelial kanaala vistarana mariyu valasalu, perisaitla niyamakam mariyu kotta rakta naalaalanu sthireekarinchadam untaayi, eee prakriya wezf mariyu angiopoitin-1 vanti proengiogenic kaarakaala niyantranapai aadharapadi untundi.
algimers vyaadhi.
neuroangeogenic kaarakaala taggudala phalitamgaa sambhavinche paristhiti algimers vyaadhi. vruddhaapyamlo nirantara neuroangiogenesis lekunda, medadulooni praantaalu ikapai kriyaatmaka kesanaalikala puurti puurakaanni kaligi undakapovachhu, anduvalla, anchanaa dwara, mastishka rakta pravaham mariyu abhignaa saamarthyam taggutaayi. vruddhaapya samayamlo neuroangiogenesis taggadam mariyu kesanaalika saandrata takkuvagaa undatam, bahusha hypoxia dwara angiogenic kaarakaala yokka balaheenamaina niyantrananu kaligi undatam, algimers vyaadhiki vascular praatipadika kaavacchu.

