
heterobimetallic utprerakam

heterobimetallic utprerakam anedi utprerakam yokka oka vidhanam, idhi rasayana praticharyanu prothsahinchadaaniki rendu ververu lohalanu upayogistundi. eee nirvachanamlo cherchabadina sandarbhaalu (pathakam 1) ikkadah 1) prati loham ververu uparitalaanni (synergistic utprerakam, "sahakaara" mariyu "dwandwa" utprerakam anae padaalatoe parasparam maarchukobadutundi.), 2) rendu lohaalu oke uparitalamtho sankarshana chendutaayi, mariyu 3) oka loham matrame neerugaa uparitalamtho sankarshana chendutundi, ayithe rendava loham modatidaanitoe sankarshana chendutundi.
synergistic utprerakam loe.
palladium yokka sanklishtatalu lithium, tinn, jink mariyu boran nundi utpannamaina vaatitho sahaa organometallic nucleophilestho electrophiles yokka cross-couplingnu utprerakam chestaayi. oka udaaharana sonogashira coupling, ikkada utpreraka raagi uppu (udhaa.zii. kui) praathamika paristhitulalo oka terminal alkine (pronucleophyl) thoo pratispandinchi raagi acetylidenu utpatti chestundi, idhi arilpalledium hallidepy transmetalate avutundi, raagi haalaidnu punarutpatti chestundi. arilpalladium acetylide nundi tagginche tolagimpu cross-kapul utpattini istundi.
itara sendriya pronucleophiles krindi udaaharanalalo (pathakam 2) arilpalladium haalaidlatho cross-kapul cheyabadataayih
1. allenoyetla bangaaru-utpreraka cyclisation taruvaata aaril ayodaidlatho cross-coupling 4-aarilbutenolaidlanu istundi.
2. styrenela borylcupression taruvaata aaril haalaidlatho palladium-utpreraka cross-coupling α-aaril-β-boromethyl functionalised aarenlanu utpatti chestundi. eee praticharya chakriya styrenes vishayamlo diasterioselectiveg cheyabadindi, mariyu oka anancioselective roopaantaram kooda abhivruddhi cheyabadindi. styrenela yokka anancioselective hydroarylation adevidhamgaa chiral copper hydride dwara saadhinchabadutundi.
3. α, β-asantrupta keatonela yokka asymmetric conjugate taggimpu-allilation anedi kyuu-hetch madhyavartitva taggimpu mariyu chiral faaks-legated palladium utprerakam dwara tadupari allilation dwara saadhinchabadutundi.
kriyaaseela nitriles (pathakam 3) yokka anancioselective allilation kooda gamaninchadaggadi. oka chiral bisphosphine-legated rhodium utprerakam alfa-keato-nitrail bhaganni daani sambandhita anoletga sakriyam chestundi, idhi adhika ananciomeric adanapu loe α-allilated naitrilnu ivvadaaniki π-allilpalladium complexes dwara addaginchabadutundi. rhodium utprerakam lenappudu anantiocelectivity gamaninchabadadu, ayithe palladium lenappudu praticharya konasaagadu.
mundugaa roopondinchina heterobimetallic utprerakaalato.
rendu loha kendraalu oke sanklishtatalo unna utpreraka vyavasthalu kooda telisinavi (udhaa.zii. shibasaki utprerakaalu); marinni udaaharanalu krinda ivvabaddaayi.
prarambha mariyu chivari parivartana loha samudaayaala ayan-jatha kalayikalu ekakaalamlo levis aamlam mariyu levis bays rendinti vanti uparitalamtho sankarshana chendutaayi. udaaharanaku, epoxidela carbonylative ring vistarana (pathakam 4) anedi [koo (koo) 4]-counter dwara ekakaalamlo ring teravadamtho kri, tii ledhaa elai yokka catanic complexela dwara levis assid activation dwara saadhinchabadutundi. phalitamgaa vachhe alcailcobalt yokka carbonylation taruvaata lactonization utpattini vidudala chestundi.
 
mancaud (pathakam 5) abhivruddhi chesina iprufuf-utpreraka sii-hetch borylation vyavasthalo heterobimetallic baand-breaking prakriya kooda upayoginchabadutundi. pinakolborenloni b-h bandham yokka bimetallic cheelika raagi hydride (iprcu-h) mariyu inupa boril [(pinn) b-fp] nuu utpatti chestundi, veetilo rendodi yuvi vikiranam meeda boriletlu nishkriyam cheyabadavu. hetch-efpi mariyu aiprku-hetch kalayika nundi hetch2 yokka bimetallic reductive elemination utpreraka chakranni tirigi praarambhistundi. utprerakamlo raagini cherchadam chaalaa avasaram; (pinn) b-fpnii upayoginchi c-h borylation anedi matrame hfp upa utpatti yokka dimerisation kaaranamgaa inumulo stoichiometric.
nirantara m1-m2 bandhaalanu kaligi unna heterobimetallic utprerakaalu rendu ververu loha kendraala paraspara charya kaaranamgaa maarpu chendina praticharyanu pradarsistaayi. udaaharanaku, binuclear complexes [klai2tii (entibup2) 2-/ pidi (η3-chii2sii (chii3) chii2)] + dwara utprerakam cheyabadina allilic amination anoohyamgaa vaegamgaa untundi. dft adhyayanalu pd → ti dietive paraspara charya anedi parivartana sthithilo pd nundi electron saandratanu upasamharinchukovadam dwara saadhaaranamgaa nemmadigaa tagginche tolagimpu dasanu vegavantam chestundani suuchistunnaayi (pathakam 6).
silika-maddatugala heterobimetallic tantalam iridium utprerakaalu (i) monometallic analogues alaage (ii) sajatiya vyavasthalaku sambandhinchi hetch/dii utpreraka marpidi praticharyalalo utpreraka paniteerunu baga penchinatlu chuupimchabaddaayi. c-h kriyaaseelata maargamlo keelaka parivartana sthithilo, dft dwara lekkinchabadutundi, indulo (i) c-h σ kakshya nundi electrophilic prarambha lohampai khaalii d kakshyaku (ta) kalisi (ii) nucleophilic sahayam kosam chivari loham (ir) nundi utpannamayye nindina d kakshya nundi c-h σ * kakshyaku (pathakam 7) tirigi ravadam untundi. anubandha ligandla dwara andinchabade steric prabhavalu sii-hetch kriyaaseelata shakti addamkulalo (ca) apaaramaina vyatyaasaalaku daariteeyavacchani gananalu choopinchaayi. 20 kilolu/moll-1) eee heterobimetallic sahakaara yantraamgamlo, lohala praapyata utpreraka paniteerupai teevramaina prabhavanni chooputundani suuchistumdi.
photordox utprerakam loe.
saampradaaya parivartana loha utprerakam thoo photordox utprerakam kalayika utpreraka chakramlo savaalu chese dasalanu nadapadaniki kanipinche kaantini upayoginchadaaniki veelu kalpistundi. udaaharanaku, nickel-utprerakam aril amination anedi kashtamaina sii-enn taggimpu tolagimpu dasato baadhapadutundi. anduvalla nikelku badulugaa, khareedaina palladium aadhaarita precatalistlanu tarachugaa sterical-encumbered phosphine ligandlatho kalipi tagginche tolagimpunu sulabhataram cheyadaaniki upayogistaaru. iteevali vidhanam madhyantara niai-amido complexes yokka single-electron aakseekarananu prabhaavitam cheyadaaniki iridium-aadhaarita photordox utprerakaanni upayogistundi. phalitamgaa vachhe niai-amido vaegamgaa taggimpu tolagimpuku lonavutundi, idhi nii-utpreraka aril aminationnu phosphine ligandla upayogam lekunda gadhi ushnograta vadda munduku saagadaaniki anumatistundi.
jeevasambandhamaina praamukhyata.
rendu ledhaa anthakante ekkuva ververu loha kendraalanu kaligi unna enjaimlu aneka mukhyamaina jeeva vyavasthalalo kanipistaayi; udaaharanaku, natrajani sthireekaranalo natrajani yokka moe-phay protein n2 nundi nh3 maarpidini utprerakam chestundi. maanava jeevasaastraaniki marinta auchityam unna kyuu-zen superoxide dismutase, superoxide, oo2-nuu oo2 mariyu hydrogen peroxidega marchadam dwara kanaalanu aakseekarana ottidi nundi rakshistundi.

