
petrenko-samskrutshenko piperidone samslaeshanha

petrenko-samskruta-praticharya anedi robinson-scop tropinone samshlaeshanhaku daggari sambandham unna oka classic bahula-bhagala-paeru praticharya, conny idhi 12 samvatsaraala kritam prachurinchabadindi.
classic praticharya.
asalaina prachuranalo diethyl-α-ketoglarate, acetonidic-carboxylic aamlam yokka utpannam, ammonia mariyu benzaldehydetho kalipi upayoginchabadutundi. saapeksha stereochemistry asalu prachuranalo spashtam cheyabadaledu, eee rojullo ex-raelu ledhaa nmr upayoginchi nirmaanaatmaka vislaeshanha andubaatulo ledhu. ammonia ledhaa ammonium lavanaalu lenappudu 4-oxotetrahydropyrona erpadutundi.
robinson samshlaeshanhaku viruddhamgaa, idhi sussinaldehyde ledhaa glutaraldehyde vanti dialdehydelanu upayoginchadu, conny benzaldehyde vanti saralamaina aldehydelanu upayogistundi. anduvalla, praticharya yokka utpatti oka cyclic nirmaanam kaadu (tropinone mariyu sudopellatiarine chudandi) conny 4-piperidone. tropinone samshlaeshanhanu petrenko-samskrutshenko praticharya yokka vaividhyamgaa chudavachu, dheenilo rendu aldehyde vidhulu oke anuvulo samayojaneeyamgaa mudipadi untaayi. hantzsh samslaeshanha kakunda, petrenko-samskrutshenko praticharya anedi bahula-bhagala ring-condensation praticharyalo aakseekarana taruvaata pondagalige konni udaaharanalalo okati. acetic aamlamlo chromium trioxide dwara aakseekarana anedi 4-pyridone anae samaroopa pratyaamnaayaaniki daariteestundi, decorboxylation 3,5-pratyaamnaaya utpannaanni istundi.
aadhunika roopaalu.
indium lavanaala samakshamlo diethyl-α-catoglarate kuu badulugaa acetoacetate nuu upayoginchavacchu. anilyn vadakam kooda asalu prachuranalo nivedinchabadindi. eee praticharya yokka utpatti sii-2 mariyu sii-6 vadda phenyl samuuhaala transoid aakruteekarananu chooputundi.
sahaja utpatti samslaeshanha.
konni ladybuglalo kanipinche alcoloid ayina precosinnellin nuu siddham cheyadaaniki eee praticharyanu upayoginchaaru.
samanvaya rasayana saastraaniki anuvartanaalu.
benzaldehydenu 2-pyridincarboxaldehy pratyaamnaayam chesinappudu, pratispandananu bissidone-ligandla kosam puurvagaamulanu siddham cheyadaaniki upayoginchavacchu. mukhyamgaa eee paddhati rendu tadupari petrenko-samskrutasemko praticharyalapai aadharapadi untundi. hydrogen peroxide samakshamlo cyclohexane aakseekarana cheyagala adhika-viluva kaligina inumu kaligina sammelanaalanu siddham cheyadaaniki eee ligandlanu upayoginchavacchu.

