
loncastuximab tessyrine

zinelaunta yaa brand navane vikale jaanare loncastuximab tessyrine heey eka monoclonal antibody sanyugmit aushadh aahe jeey mothya bii-seela lymphoma aanee uchch darjachya bii-seela lymphomachya upcharansathi vaparale jaate. heey eka pratipind-aushadh sanyugma (aii. dii. see.) aahe jeey see. dii. 19 prathinanna lakshya karananya manavikrut pratipindanni banalele aahe.
sarvat samanya dushparinamadhye gamma-glutamiletransferase (jee. jee. tii., yakrutatil enzyme), neutropania (neutrofilschi qamee patali, pandhya raktapesheencha eka prakar), thakwa, raktakshay (laal raktapeshinchi qamee patali), thrombocytopenia (raktatil plateletschi qamee patali), malmal (aajari padane), paridhiy sooj (drav dharan jhalyamule sooj yene, visheshtah ghotya aanee paay) aanee pural yancha samavesh hoto.
april 2021 madhye americet aanee december 2022 madhye european unionmadhye vaidyakeey vaparasathi loncastuximab tessirinla manyata denyat aalee. us food andd drugg administration (fda) heey pratham shreniche aushadh manate.
vaidyakeey vapar.
loncastuximab tessyrine heey punha udbhavnare kinwa apavartak mothe bii-seela lymphoma aanee uchch darjache bii-seela lymphoma asalelya praudhanchya upcharansathi soochit kele jaate.
tantradnyan.
manavikrut monoclonal pratipind heey valine-allenine vichchedanaksham, myalimide linkardware cytotoxic (karkarogvirodhi) pyrolobenzodiazepine (pii. bii. dii.) diamershee yadruchchikpane sanyojit kele jaate. pratipinde see. dii. 19shhee bandhali jaatat, eka prathine jee lymphoma aanee leukemiachya kahee prakaransah bii-seela hematological tumourchya prushthbhagavar atyant vyakt kelee jaate. arbud peshinshi bandhalyanantar pratipinde antargat kelee jaatat, cytotoxic aushadh pii. bii. dii. sodale jaate aanee karkarogachya peshi nasht kelya jaatat. vividh actinomycetsdware utpadit naisargik utpadanancha eka varg asalelya pii. bii. dii. monomarsmadhun pii. bii. dii. diamer tayar kele jaatat. pii. bii. dii. diamer heey dii. aine. aii. chya vishisht sthalanna paraspar jodine kaam karatat, jyamule karkarogachya peshinche vibhajan hote jyamule peshi martat. dii. aine. aii.-crossling agentscha eka varg mhanoon teey pranaligat chemotherapeutic aushadhanpeksha lakshaniyaritya adhik shaktishali aahet.
itihas.
done tappyanchya pahilya chachanyanmadhye, punha udbhavananya kinwa apavartak bii-peshi naun-hodgkins lymphoma aanee punha udbhavananya kinwa apavartak bii-peshi tivra lymphoblastic leukemia asalelya lokanmadhye aushadhache moolyankan kele jaate. pahilya tappyatil ghatak lymphomachya antarim parinamanvaril 14 vya aantarrashtriy parishadet, punha udbhavalelya kinwa apavartak nasalelya hodgkins lymphomamadhye loncastuximab tessirinchya upcharache moolyankan karnyasathi tayar kelela open-label, doses-escalating abhyas sadar karnyat aala. deta cutoffchya velee nondani kelelya rugnanmadhye ekoon pratisad darr ekoon rugna loksankhyet 61 takke hota (42 takke sampoorn pratisad aanee 19 takke aanshik pratisad) aanee punha udbhavananya kinwa apavartak pasarlelya mothya bii-seela lymphoma (dii. ell. bii. see. ell.) asalelya rugnanmadhye ekoon pratisad darr 57 takke hota (43 takke sampoorn pratisad aanee 14 takke aanshik pratisad).
loncastuximab tessirinla eff. dii. aii. neey mothya bii-peshi lymphomachya prasaravaril upcharansathi anath aushadh mhanoon manyata dilee hotee.
samaj aanee sanskruti.
kayadeshir sthitee.
15 september 2022 roji, european medicine agency (eae. emm. aii.) chya manvi vaparasathichya aushadhi utpadananchya samiteene (see. etch. emm. pii.) eka sakaratmak mutt sweekarle, aanee aushadh utpadan zinelaunta sathee vipanan pradhikaran denyachi shifaras kelee, jeey mothya bii-seela lymphoma (dii. ell. bii. see. ell.) aanee uchch darjachya bii-seela lymphoma (etch. jee. bii. ell.) asalelya praudhanchya upcharansathi aahe. yaa aushadhi utpadanasathi arjdar aii. dii. see. therapeutics (aine. ell.) bii. aahe.vhee. december 2022 madhye european unionmadhye vaidyakeey vaparasathi loncastuximab tessirinla manyata denyat aalee.
sanshodhan.
tyachi krutichi yantrana lakshat gheta, qaar-tii seela therapisathi apatra asalelya rugnanmadhye loncastuximab tessyrine aakarshak asoo shakate.