sacubitril

sacubitril (; inn) heey eka uchch raktadabavirodhi aushadh aahe jeey valsartanchya sanyogane vaparale jaate. sacubitril/valsarton heey sanyukt aushadh, jeey chachanyandarmyan "ell. see. etch. 696" mhanoon olakhale jaate aanee "entresto" yaa brand navane vikale jaate, heey hrudayavikarachya zatkyasathiche upchar aahe. 7 julai 2015 roji hrudayavikarachya babatit eff. dii. aii. chya pradhanyachya punaravalokan prakriyeantargat tyala manjuri denyat aalee.
dushparinam.
sacubitrilmule bradykininchi patali vadhate, jee aushadh asalelya rugnanmadhye kadhikadhi kadhikadhi soojasathi jababdar asate. mhanunach fuffusanchya soojcha itihas asalelya rugnansathi ess inhibitorschya vaparasah aushadhachi shifaras kelee jaat nahee.
krutichi yantrana.
sacubitril haah eka utpadan aahe joou esteresesdware dii-ithileshandware sacubitrilate (ell. bii. kyu. 657) madhye sakriy hoto. sacubitrilate neprelicin yaa enzymela pratibandhit karate, jeey alind aanee menduchya natriuretic peptidechya peptidechya jababdar aahe, done raktadab qamee karnare peptides jeey pramukhyane raktache praman qamee karoon kaam karatat. yavyatirikt, neprelicin heey bradykinin yaa dahak madhyasthasah vividh peptidesche vighatan karate.

