
aine grabiel

aine martin grabil (janm 1942) heey eka sanstheche pradhyapak aanee massatusates institute auph technologymadhil mendu aanee sandnyanatmak vidnyan vibhagat pradhyapak sadasya aahet. tyaa mcgovern institute phaur brain risarchmadhye dekhil sanshodhak aahet. tee besal ganglia aanee savayi tayar karnyachya neurophysiology, antarnihit shikshanavar tadnya aahe aanee tiche kaam parkinson rog, huntington rog, obsessive-compulsive disorder, madak padarthancha durupyog aanee besal gangliaver parinam karananya itar vikaranshi sambandhit aahe.
sanshodhan.
tichya karkirdichya bahutansh kalasathi, grabielne striyatamchya sharirshastravar laksh kendrit kele aahe, jee halchal, aakalanshakti, savayi tayar karane aanee nirnay ghenyachya niyantranat guntaleli besal ganglia rachana aahe. 1970 chya dashakachya uttaradhat, grabielne shodh lavala qee jaree pattiy neurons eka anakar dravyaman asalyache disat asale, taree teey pratyakshat rasayanik vibhaganmadhye sanghatit hote, jyala tine striosome mhatale. nantarchya sanshodhanat stereosomal vikrutee aanee majjatantusambandhi vikar, jase qee huntinton rogatil manahsthitichi nishkriyata aanee parkinson rogat dopaminechi kamatarata yanchyatil sambandh ughad jhaale.
grabilchya tyanantarchya sanshodhanat heey disun aale qee pattyachi modular rachana aakalanshakti, shikshan aanee savayi nirmitishi kashee sambandhit aahe. teela aadhalale qee majjatantu ekach sharirachya bhagavar niyantran thevana sanvedi aanee motor corticeschya bhagatoon prakshepit hotat aanee pattyamadhye ekatra gumphalele asatat, jyamule matrisome tayar hotat. grabielne pudhe dakhavun dile qee sharirachya pratyek bhagasathi matrisome astitvat aahet aanee teey majjatantu, aaklan aanee motor niyantranasathi jababdar asalela pradesh, menduchya khodala, halchalinche samanvay karnara pradesh, neocortaxla jodana loopmadhye sanghatit kele gele hote. undeer aanee narvanar pranyanchya abhyasatoon asey disun aale qee savayi tayar karnyasathi matrusattak heey mahattvapoorn hote.
nantarchya kamat, grabielne pratham pattyamadhye aanee nantar infralymbic cortexmadhye dakhavun dile qee, jevha savay tayar hote tevha neuronal kriyakalapanchi task-brackett kinwa "chunking" pattern udbhavate, jyamadhye nehamiche karya suru jhalyavar neurons sakriy hotat, karyadarmyan thodi kriyashilata darshavtat aanee karya purn jhalyavar punha sakriy hotat.
alikadil karyat, grabielne vartanukichya kamadarmyan parkinson rogane prabhavit jhalelya neuronschya kriyakalapanvar dopaminechya qamee honyachya parinamache vishleshan karnare pahile vyakti asanyabarobarach, savayichi nirmiti, shikshan aanee aaklan aanee nirnay ghenyachya paddhati yasarkhya vartanache moolbhut pailu olakhanyavar laksh kendrit kele aahe.
karkird.
grabielne harvard vidyapithat jivashastra aanee rasayanshastrat padvyuttar shikshan ghetale, 1964 madhye padvi prapt kelee. 1966 madhye tufts vidyapithatun jivashastrat emm. aii. prapt kelyanantar, tine hans-lucas tuber aanee walley nauta yanchya margdarshanakhali emm. aay. tii. yethe manasshastra aanee mendu vidnyanat doctorate abhyas suru keela. 1971 madhye tine ph. dii. prapt kelee aanee 1973 madhye tee emm. aay. tii. vidyashakhet ruju jhaali.
1994 madhye teela 'daad walter aaa' asey naav denyat aale. mendu aanee sandnyanatmak vidnyan vibhagat rosenblith neuroschya pradhyapika hotya aanee 2001 madhye tyanna emm. aay. tii. mcgovern institute phaur brain risarchmadhye sanshodhak mhanoon niyukt karnyat aale. 2008 madhye tyanna sansthechya pradhyapika mhanoon niyukt karnyat aale.
puraskar aanee manyata.
2001 madhye, grabil yanna 'menduchya shareer rachnashastra aanee shariravidnyan samajoon ghenyachya tyanchya agraganya yogdanasathi, jyat rachana, rasayanshastra aanee vichar aanee halchalinna aadhar denanya marganche karya samavisht aahe,' yasathi rashtrapatinche rashtriy vidnyan padak pradan karnyat aale."2012 madhye, teela, aaklan aanee nirnayat antarbhut asalelya moolbhut majjatantu yantraneche spashtikaran dilyabaddal, cornelia bergman aanee winfried denk yanchyasamvet, majjatantushastratil kavali puraskarane sanmanit karnyat aale."
2018 madhye, grabielne okihide hikosaka aanee wolfram schultzs neurosciencemadhil gruber puraskar jinkla. tyanchya karyane moolbhut gangliachya abhyasat moolbhut badal ghadavun aanala aahe aanee mendu naveen savayi aanee kaushalye kashee shikato aanee rakhoon thevato, halchali vyavasthapit karato aanee shikanyasathi aanee nirnay ghenyasathi bakshise prakriya karato yabaddal prabhavshali naveen kalpana nirman kelya aahet. yamule neurodegenerative aanee neurocychiatric vikaranchya vistrut shrenibaddalchi aapali samaj dekhil adhik sakhol jhaali aahe jyamadhye besal ganglia aanee vartanukivaril niyantranat tadjod kelee jaate.
"jevha yaa teen vilakshan shastradnyanni tyanchya karkirdila suruvat kelee, tevha phaar qamee lock besal gangliakade jaast laksh dett hote", dow. mhanatat. robbert wurtz, nih heey pratishthit sanshodhak aanee nivad sallagar mandalache adhyaksh hote. aaj, tyanchya agraganya sanshodhanamule, menduche heey kshetra menduchya samanya karyat aanee vartanat jee madhyavarti bhoomika bajavate tee aata aapan olakhato. tyanchya karyache mahatva [jastiche] sangitale jaau shakat nahee, kaaran parkinson rog, huntington rog aanee ammali padarthanche vyasan yasah aaplya menduchya kahee sarvat vinashkari vikaranmagil majjatantushastrabaddal aapali samaj dekhil yamule badalali aahe."
grabielne shodh lavala qee besal gangliamadhil sarvat mothe kendrak asalelya striyatamchi eka jatil, modular rachana aahe. tyanantar tine yaa parivartanshil shodhache anusaran kele aanee tyaa sanrachanechya karyatmakateche varnan karananya abhyasansah, shikanyachya prakriyedarmyan striyatal neural kriyakalapanmadhil badalanmule pathological savayi tayar hotat, jase qee obsessive compulsive disorderche vaishishtya.tyaa us national academy auph sciences, american academy auph arts andd sciences, american philosophical society aanee national academy auph medicine (purvichi institute auph medicine) chya sadasya aahet.