see. dii. see. 6

see. dii. see. 6, kinwa peshi vibhajan chakr 6, heey eukariotic peshinmadhil eka prathine aahe. yacha abhyas pramukhyane ugavatya yeast 'sacharomysis serevisi' () madhye keela jaato. heey dii. aine. aii. pratikrutiche eka aavashyak niyamak aahe aanee ess. fages aanee mitosische samanvay samanvay peshi chakratil tapasani kendra yantranechya sakriyakaranat aanee dekhbhalimadhye mahattvachi bhoomika bajavate. heey purv-pratikruti sankulacha (purv-aar. see.) bhag aahe aanee dii. aine. aii. varr sookshm gunasutra dekhbhal (emm. see. emm.) prathine loaded karnyasathi aavashyak aahe, jee dii. aine. aii. sanshleshan suru karnyasathi eka aavashyak payari aahe. yavyatirikt, too aaa + etpaceschya kutumbatil sadasya aahe aanee orc 1 shhee atyant sambandhit aahe; aarkiyamadhye donhi samaan prathine aahet. 
karya.
see. dii. see. 6 heey aii. tii. pii. bandhan prathin aahe aanee mool olakh sankul (oo. aar. see.), see. dii. tii. 1 aanee emm. see. emm. sankul (emm. see. emm. emm. asalele) yasah purv-pratikruti sankul (purv-aar. see.) chey sadasya aahe. see. dii. see. 6 heey oo. aar. see. nantar aii. tii. pii. varr avalambun asalelya paddhatine ekatra hote aanee dii. aine. aii. varr emm. see. emm. prathine loaded karnyasathi aavashyak asate. electron sukshmadarshakachya pratimanchya punarbandhanitun asey disun aale qee qee sankul ring-aakarachya mcm helikesachya aakarmanansarkhich eka ring-aakarachi rachana tayar karate. dii. aine. aii. saha sampoorn qee-seedeetii1-mcamaam2-7 (oo. see. emm.) sankulache jawalche aanvik-sankalp model 2017 madhye eae. emm. detavarun ekatra kele gele.
asey manale jaate qee see. dii. see. 6-see. dii. tii. 1 sankul emm. see. emm. donatchya madhyavarti chhidratun dii. aine. aii. dhaga kadhanyasathi aii. tii. pii. jalvichhedan vaparte. see. dii. see. 6 chya bandhan rachneteel utparivartan heey jordarpane soochit karate qee aii. tii. pii. bandhan aanee jalvichhedan heey tyachya karyasathi aavashyak aahe. dii. aine. aii. bandhanichi kiman aavashyakta tyachya 47-emino acid kramanusar mapp kelee gelee aahe. shivay, see. dii. see. 6 apratyakshapane pii. 34. see. dii. see. 2/see. dii. see. 28 emm. fages kinesachya sakriyates pratibandh karate, asha prakare anoo vibhajan dadapale jaate.
niyam.
peshi chakrachya teey tappyadarmyan see. dii. see. 6 samanyatah uchch staravar upasthit asato. yache anshatah kaaran see. dii. see. 6 januk keval jee. 1 tappyat lipyantarit kele jaate. ess tappyachya prarambhi, prarambhi heey heey sankuladware sankuladware phosphorylated hote aanee parinami nishkriy hote. heey see. dii. see. 2 phosphorylationsathy (aine-terminsjaval) sarvasamaveshak thikani see. dii. see. 6 madhye utparivartan karoon darshavile gele aahe jeey jeey rokhate. shivay phosphorylation see. dii. see. 28-see. ell. aine. dware utprerit kele jaau shakate. nishkriy see. dii. see. 6 nantar ess. see. eff. see. dii. see. 4-aadharit sarvavyapi nirjalikaranadware adhahpatanasathi lakshya kele jaate aanee nantar proteezomdware adhogati hote. asha prakare, see. dii. see. 6 chey niyaman see. dii. keey. 2 chya kriyakalapashi ghattapane sambandhit aahe aanee see. dii. keey. 2-kriyakalap prati peshi chakrat ekdach dolan karat asalyane, see. dii. see. 6 chey sanchay aanee avanati dekhil dolan karate.
done rajye vegali karata yetat. pahilya sthiteet sthiteet tappyat) see. dii. keey. 2-kriyakalap qamee aahe, see. dii. see. 6 jamaa houu shakate, mhanoon purv-aar. see. tayar keela jaau shakato parantu sakriy keela jaau shakat nahee. nahee sthiteet see. dii. keey. 2-kriyakalap jaast asato, see. dii. see. 6 nishkriy hoto, mhanoon purv-aar. see. sakriy hoto parantu tayar hott nahee. haah badal khatri deto qee dii. aine. aii. pratikrutikaran pratyek peshi chakrat fakt ekdach kele jaate. heey dakhavun denyat aale aahe qee see. dii. see. 6 chee atiprabhavyata sandnyanatmak peshinmadhye punha pratikruti nirman karat nahee, bahudha peshi reset reset see. dii. keey. chya madhyamatoon pratibandhamule
chakr ghadyal teey teey. tathapi, asey suchavale gele aahe qee see. dii. see. 6 chey niyaman hii anek anavashyak yantrananpaiki eka aahe jee eukariotic peshinmadhye dii. aine. aii. chee punha pratikruti rokhate.
rachana.
archaean "pyrobaculum aerophilum" madheel see. dii. see. 6/oo. aar. see. 1 sambandhit prathinanchi sphatikshastriy rachana sodavanyat aalee aahe aanee teen sanrachanatmak kshetre olakhali gelee aahet. domain I aanee II heey aii. tii. pii. bandhan/jalvichhedan sthal tayar karatat aanee itar aaa + aii. tii. pii. ess. sarkhech asatat. domain III sanrachanatmakdrushtya pankhanchya-helics domenshee sambandhit aahe, tyamule mool dnac sanvad sadhu shakate. eae. saha abhyasatoon. kolai γ clamp loading complexes, asey suchavale gele hote qee domain III purv-aar. see. madheel itar aaa + atpaces prathine-prathine parasparsanvadat madhyasthi karate, asha prakare asey soochit karate qee see. dii. see. 6 tyachya mool swarupat homodymer tayar karate. 1 aanee 2 heey kshetra kajoochya aakaracha renu tayar karatat jeey fatemadhye aii. tii. pii. bandhatat aanee aii. tii. pii./aii. dii. pii. olakhanyasathi sanvedak rachana atiriktapane tayar karatat. hii kshetre tyanantarchya sanrachanatmak badalanmadhye madhyasthi karatat asehi manale jaate. tathapi, yaa kshetranchya achook karyatmak bhoomika adyap aspasht aahet.
rog.
heey see. dii. see. 6 madhye proto-oncogenic kriyakalap darshavile gele aahe. see. dii. see. 6 atiprakshep shaee 4/aii. aar. eff. tumour suppressor janukanchya abhivyaktimadhye shaee 4/aii. aar. eff. locus yethe chromatinechya epigenetic badalancha samavesh asalelya yantranedvare hastakshep karato. yavyatirikt, prathamik peshinmadhil see. dii. see. 6 atee-abhivyakti dii. aine. aii. hyper-pratikrutila protsahan deu shakate aanee oncogene sakriyatemule sakriyatemule vruddhatvachya pratisadas pravrutt karoo shakate. heey nishkarsh soochit karatat qee manvi peshinmadhil see. dii. see. 6 abhivyaktiche niyaman radd kelyane carcinogenesischa gambhir dhoka nirman hoto. prostate karkarogamadhye see. dii. see. 6 chey qamee-niyaman disun aale aanee teey aakramak prostate karkarogachya phenotypic vaishishtyanshi sambandhit hote. shivay, asey
heey disun aale aahe qee see. dii. see. 6 heey garbhashayacha karkarog, fuffusacha karkarog aanee menduchya karkarogamadhye mothya pramanat niyantrit aahe.

