
delta-beeta thalassemia

delta-beeta thalassemia haah thalassemia eka durmil prakar aahe jyamadhye haemoglobin subunit delta aanee haemoglobin subunit beetache utpadan qamee hote aanee haemoglobin subunit gamachi patali vadhate. haah eka autosomal recessive disorder aahe.
chinhe aanee lakshane.
delta-beeta thalassemia asaleli vyakti sahasa lakshane nasaleli asate, tathapi jethe laal rakt peshi asamanyapane lahan asatat tethe microcytosis houu shakato.
yantrana.
delta-beeta thalassemia haah autosomal recessive disorder aahe, jyacha arth palak doghehi prabhavit aahet aanee janukachya done pratee upasthit asane aavashyak aahe. eka vahkala haemoglobin aaa tayar karnyasathi eka samanya januk milate, eka palkakadoon aanee dusra palak eka januk puravato jyamule haemoglobin aaa hott nahee. delta-beeta thalassemia durmil manla jaato.
delta-beeta-thalassemia haah sampoorn delta aanee beeta janukanchya anukramanchya vilopanamule hoto aanee keval gamma-globin aanee etch. bii. eff. tayar hotat. kvachitach, gair-vibhajanshil swarupanchi nond jhaali aahe.
jevha done delta 0 utparivartan varshane midatat, tevha haemoglobin aii 2 (alfa 2, delta 2) tayar hott nahee. heey nirupadravi aahe kaaran samanya praudh haemoglobin fakt 2-3% heey haemoglobin aii2 asate. vyaktimadhye samanya raktavahinyasambandhi mapdand (erythrocyte ganana, ekoon haemoglobin, sarasari pesheey aakarman) asateel. delta-beeta thalassemia heey darshavite qee eka utparivartan + 69 sthiteet aahe.
beeta thalassemiashi sambandh.
delta-beeta thalassemia beeta thalassemia vaishishtyache nidan lapavoo shakato. beeta thalassemia, haemoglobin aii2 madhye vaadh hote, parantu delta-beeta thalassemia utparivartanachya saha-astitvamule haemoglobin aii2 chey moolya samanya shreneet qamee hoil, jyamule beeta thalassemia vaishishtyache nidan aspasht hoil.
nidan.
hypochromic microcytic laal raktpeshinchya shodhanantar, delta-beeta thalassemiachi pushti uchch-karyakshamatechya drav chromatographidware hote.
upchar.
garaj bhasalyas raktastravasathi, jase qee rakt sankraman, upchar vaparale jaatat.
stame seela pratyaropan haah aanakhi eka paryay aahe, parantu daata aanee asthi majja pratyaropan prapt karnari vyakti susangat asane aavashyak aahe, tyat samavisht asalelya jokhaminche moolyankan kele pahije.