tii. aine. eff. ess. eff. 12

tumour necrosis factor legand super family member 12 jyala tii. aine. eff.-sambandhit durbal prerak auph apoptosis (tweak) mhanoon dekhil olakhale jaate, heey eka prathine aahe jeey manavanmadhye "tii. aine. eff. ess. eff. 12" janukadware encode kele jaate.
karya.
tweak 1997 madhye shodhala gela. yaa janukadware encode kelele prathin heey eka cytokine aahe jeey tumour necrosis factor (tii. aine. eff.) legand kutumbatil aahe. heey prathin eff. aine. 14/twicker receptorsathi legand aahe. yaa cytokinemadhye tii. aine. eff. saha ativyapi sanket karye aahet, parantu uutinche vitaran adhik vyapak aahe. leukocytes heey manvi vishranti aanee sakriy monocytes, dendritic peshi aanee naisargik ghatak peshi yasah twickche mukhya srot aahet. peshi-vishisht paddhatine peshi mrutyuchya anek margandware tweak apoptosisla pravrutt karoo shakate. heey cytokine endothelial peshinchya prasar aanee sthalantarala protsahan dete aanee asha prakare angiogenesische niyamak mhanoon karya karate.
vaidyakeey mahatva.
dirghakalin sooj, fibrosis aanee angiogenesis rogshastriy uutinmadhye badalanna protsahan denyasathi junat dukhapatimadhye tweak pathvechya atee sakriyateche varnan kele gele aahe. udaharanarth, dirghakalin yakrutachya aajarat, tweak expression vadhate aanee yakrutachya tantumay granthiche pramukh niyamak asalelya yakrutachya stellet peshincha prasar hoto.

