
trans-splissing

"trans"-splissing haah aar. aine. aii. prakriyecha eka vishesh prakar aahe, jyamadhye done vegvegalya prathamik aar. aine. aii. pratilekhanmadhil exon shevat teey shevatparyant jodale jaatat aanee jodale jaatat. jaree kahee jivanu aanee aarkiyamadhye tranasathi "ardh-januk" dekhil asatat, taree heey sahasa eukeriotsmadhye aadhalate aanee spliciosomdware madhyasthi kelee jaate.
aanuvanshik 'trans'-splissing.
samanya" ("sis"-) splissing ekach renuvar prakriya karate, tarr "trans"-splissing anek vegalya purv-emm. aar. aine. aii. pasoon ekach aar. aine. aii. pratilekh tayar karate. utparivartit januk utpadananna sambodhit karnyasathi yaa ghatanecha vapar aanvik upcharansathi keela jaau shakato. aanuvanshik trans-splicingmule aar. aine. aii. vividhatet parivartansheelata yete aanee proteomchi jatilata vadhate.
oncogenesis.
kahee sanlayan pratilekhan samanya manvi peshinmadhye 'trans'-splicingdware hote, tarr 'trans'-splissing hii kahee oncogenic sanlayan pratilekhanmagil yantrana dekhil asoo shakate.
ess. ell. "trans"-splissing.
spliesed leader (ess. ell.) "trans"-splicingcha vapar vishisht sukshmajiv karatat, visheshtah kinetoplaste vargache protest januke vyakt karnyasathi karatat. yaa jivanmadhye, eka aachchhadit splies leader aar. aine. aii. lipyantarit kele jaate aanee tyach velee, januke lamb polycystronmadhye lipyantarit kelee jaatat. capped splies leaderla 'trans'-pratyek janukavar eksandh capped aanee polyadenylated pratilekhan tayar karnyasathi vibhajit kele jaate. heey lavkar-valanare eucariots kahee intron vapartat aanee tyanchyakade asalele spliciosome tyanchya sanrachanechya asemblimadhye kahee asamanya badal darshavtat. cappingmadhe vishesh bhoomikansah tyanchyakade anek eae. aay. eff. 4eae isophorm dekhil aahet. trans-splicingmadhun jaananya khalchya prajatinmadhye spliesed leader kram atyant sanrakshit keela jaato. udaharanarth trypanosomes. peshimadhye vibhajit netyachi bhoomika maheet nasali taree tee anuvad aarambhamadhye samavisht asalyache manale jaate. see madhye.elegans, "anukram netyache vibhajan diksha kodanchya jawal hote. kahee shastradnya asehi suchavatat qee peshi vyavharyatesathi haah kram aavashyak aahe. eskerismadhye, aar. aine. aii. januk lipyantarit karnyasathi spliesed leader kram aavashyak asato. vibhajit neta kram haah diksha, emm. aar. aine. aii. sthanikikaran aanee anuvad diksha kinwa pratibandhasathi jababdar asoo shakato.
kahee itar eukariotes, visheshtah dynophlagelates, spunge, nematodes, niderian, tinephore, flatworm, crustatians, chettogneth, rotifers aanee tunicatesmadhye dekhil qamee-adhik pramanat slu "trans"-splicingcha vapar karatat. tunicate "sayna aantr" madhye, ess. ell. "trans"-splicingchi vyapti, "trans"-spliesed viruddha naun-"trans"-spliesed janukanchya dwaiti aanee paramparik vargikaranapeksha varanvar aanee kvachitach "trans"-spliesed janukanna olakhananya parimanatmak drushtikonatun adhik changlya prakare varnan kelee jaate.
ess. ell. 'trans'-vaiyaktik 5 '-cap kelelya emm. aar. aine. aii. madhye opronchya polycystronic transcriptchya resolutionmadhye splissing karye. jevha bahyakananna cystronchya khulya vachan chaukatila lagoon asalelya, adhomukhi sweekarak sthalanmadhye 'trans'-vibhajit kele jaate, tevha hii prakriya sadhya hote.
yantrana.
trans-splissing heey done swatantra exonche lipyantarit aar. aine. aii. jodane dware darshavile jaate. yaa splicingsathicha sanket emm. aar. aine. aii. chya 5 'tokavaril bahyarekha aahe, varchya bajula karyarat 5' splies sitechya anupasthitit. jevha 5 'outron splies keela jaato, tevha splies kelelya leader aar. aine. aii. chee 5' splies site outronla shakhankit kelee jaate aanee madhyavarti tayar hote. yaa payarimule mukt spliesed leader exon tayar hoto. tyanantar purv-mruna varr pahilya exonmadhye exon jodala jaato aanee madhyavarti sodale jaate. trans-splissing heey sis-splicingpeksha vegale aahe kaaran prii-marnavar 5 'splies site nahee. tyaeivaji 5 'splies site slies sequencedware pradan kelee jaate.
indriy aanee indriyavirodhi strands darmyan trans-splissing.
pratilekhan hott asalelya indriy tantuncha parinam mhanoon, eka purv-mruna tayar hote jee indriy tantunna purak asate. anty-sains strandche dekhil lipyantar kele jaate, parinami eka purak prii-marnah strand tayar hoto. done pratilekhanmadhil exon ekatra jodale jaatat aanee chimerick mruna tayar hotat.
paryayi trans-splissing.
paryayi trans-splicingmadhye intragenic trans-splissing aanee intergenic trans-splicingcha samavesh aahe. antarjaivik trans-splicingmadhye purv-mrunamadhye exonchi nakkal samavisht asate. done vegvegalya janukanchya purv-mrunapasoon tayar jhalelya exonche ekatra vibhajan heey aantar-janukeey trans-splicing vaishishtya aahe, parinami trans-janukeey mruna hote.