manvi

humanine heey mitochondrial genomemadhe 16 chya ribosomal aar. aine. aii. janukadware encode kelele micropeptide aahe, emm. tii.-aar. aine. aar. 2. tyachya sanrachanet teen-valane α-helics asate aanee samamiti nasate.
inn vitro' aanee pranyanchya pratikrutinmadhye, tyache cytoprotective prabhav asalyache disate.
januk.
humaninela mitochondrial genomemadhe 16 chya ribosomal aar. aine. aii. janukadware encode kele jaate, emm. tii.-aar. aine. aar. 2. aanvik genomemadhe (aanvik mitochondrial dii. aine. aii. vibhaganmule) anek paralog aadhaltat aanee tyanna emm. tii. aar. aine. aar. 2 ell. asey naav dile jaate aanee tyanantar eka sankhya asate. heey samantar samaroop purnapane aprakat aahet qee nahee yachee purnapane khatri nahee.
prathine.
vyakt kelelya peptidemadhye teen-valane α-helics asate aanee tyat samamiti nasate.
peptidechi lambi tee kuthe tayar hote yavar avalambun asate. jarr teey mitochondria aat tayar jhaale tarr teey 21 amino acid lamb asel. jarr teey mitochondria baher, cytosolmadhye tayar jhaale tarr teey 24 amino acid lamb asel. donhi peptidesmadhye jaivik kriya asalyache disun aale aahe.
itar prajati.
ratus norwegicus" yaa undaramadhye "rattin" (humaninsarkhe prathin) heey januk asate, jeey humanineshy samaroop asalele 38 amino acid peptide encode karate. donhi januke see. dii. aine. aii. tayar karatat jee 88 takke anukram olakh darshavtat. peptides 81 takke eksarkhe asatat, rattinmadheel carboxyl terminal kram humaninpeksha 14 amino acid jaast asato. undaranchya urvarit kramatil 24 amino aamlanpaiki 20 manvi kramatil amino aamlansarkhech aahet.
mouse emm. tii.-aar. aine. aar. 2 humanine ortholog heey eka chhadmajan aahe, tyamule emm. tii. dii. aine. aii. madhoon konatehi humanine tayar hott nahee. tathapi, anoo genomemadhe (manavanpramanech) mitochondrial genomechya anek pratee aanee humanine homologchi eka prat, "jee. emm. 20594" (), sakriyapane vyakt kelee jaate.
karya.
humaninche anek cytoprotective prabhav aahet.
parasparsanvad.
jee. pii. 130, doubleu. ess. ex. 1 aanee see. aine. tii. eff. aar. neey banalelya tripakshiy receptorshee bahya koshikeey parasparkriya, tasech formill peptide receptor 2 (formilpeptide-sarkhya-1 receptor) shhee parasparkriya prakashit jhaali aahe.
humaninchya prabhavasathi backs, tii. bii. aay. dii., aay. jee. eff. bii. pii. 3 aanee aanee saha antahkoshikiy parasparsanvad dekhil aavashyak asoo shakato.
shodh.
vegvegalya mapdandancha vichar karoon teen vegvegalya prayogshalanni swatantrapane humanine shodhale. 2001 madhye prakashit karnari nisimoto prayogshala hii pahili hotee, jine alzheimer rogacha eka pramukh ghatak asalelya amyloid beeta pasoon peshinche sanrakshn karoo shakanari sambhavya prathine shodhat asatana humanine shodhale. apoptosismadhye guntalelya bii. see. ell.-2-sambandhit ex prathinanshi (backs) parasparsanvad sadhu sadhu prathinanchi tapasani kartana reed prayogshalet humanine aadhalale. aay. jee. eff. bii. pii. 3 shhee parasparsanvad parasparsanvad prathinanchi tapasani kartana pinchas cohain prayogshalene swatantrapane humanincha shodh lavala.
sanshodhan.
sanvardhit peshincha vapar karoon kelelya prayoganni heey dakhavun dile aahe qee humaninche neuroprotective tasech cytoprotective asey donhi parinam aahet aanee kruntakanmadhil prayoganmadhye asey aadhalun aale aahe qee alzheimer rog model, huntington rog model aanee stroke modelmadhye tyache sanrakshanatmak parinam aahet.
humaninche asankhya neuroprotective aanee cytoprotective prabhav prastavit aahet. peshi aanee kruntak yaa donhi abhyasanmadhye asey aadhalun aale aahe qee humanine kinwa humanine derivativeschya vaparamule alzheimer rogachya pratikrutinmadhye astitva aanee/kinwa sharirik mapdand vadhatat. alzheimer rogavyatirikt, humaninche huntington rog, prion rog aanee strokechya pratikratinviruddha itar neuroprotective prabhav aahet. sambhavya neuroprotective prabhavanchya palikade, humanine oxidative taana, atherosclerotic plake tayar hone aanee hrudayavikarachya zatkyapasun sanrakshn karate. 
chayapachay prabhav dekhil disun aale aahet aanee humanine swadupindachya beeta-peshinche astitva sudharnyas madat karate, jeey type 1 madhumehas madat karoo shakate aanee insulin sanvedansheelata vadhavate, jeey type 2 madhumehas madat karoo shakate. undaranmadhye, humanine analogue glukojchi patali samanya karate aanee madhumehachi lakshane qamee karate.
alzheimer rogatil adhogatiche kaaran asalelya beeta-amyloidchya visharipanapasun neuronsche sanrakshn karanyachi humaninsarkhich kshamata rattin darshavite.
lahan humaninsarkhe peptides heey mitochondrial 16s rrna madhye aadhalanare peptidesche eka gut aahet aanee tyat pratigami sanket karye dekhil asatat.

