kaap (chemotherapy)

chop heey naun-hodgkin lymphomachya upcharanmadhye vaparlya jaanarya chemotherapychya aahar paddhatiche sankshipt roop aahe. kapmadhye khaleel goshtincha samavesh hotoh
kadhikadhi aar-chop aahar tayar karnyasathi yaa upchar paddhatimadhye chimerick chimerick monoclonal antibody, retooksimab jodali jaate.
dosing niyam.
aar-maxie-chop haah aavaran peshi lymphomamadhye vaparla jaato aanee 21 divasanchya antarane deela jaato, aar-etch. dii. aii. see. (retooksimab + uchch-matra citerabine) saha paryayane deela jaato.
itar bahutek naun-hodgkin lymphomamadhye (kahee aakramak prakar vagalata), manak-doses [aar]-chop samanyatah pahilya-ola upchar mhanoon vaparla jaato.
vapar aanee sanket.
chemotherapy aushadhanmule jhalelya nukasanichi durusti karnyasathi karkarogachya peshinpeksha samanya peshi adhik saksham asatat.
jarr lymphoma haah bii peshi moolcha asel tarr haah aahar monoclonal antibody retooksimabs dekhil jodala jaau shakato; yaa sanyojanala aar-chop mhanatat. samanyatah, abhyaskram done kinwa teen aathvadyanchya antarane (anukrame chop-14 aanee chop-21) prashasit kele jaatat. rog upcharanna pratisad dett aahe qee nahee yache moolyankan karnyasathi samanyatah teen chakrannantar seaty scan kele jaate.
hriday v raktavahinyasambandhi rogacha itihas asalelya rugnanmadhye, doxorubicin (jeey cardiotoxic aahe) haah khoop motha dhoka manla jaato aanee aaharatoon vagalala jaato. yaa sanyojanala nantar cop (cyclophosphamide, onkovin aanee prednisone kinwa prednisolone) kinwa see. vhee. pii. (cyclophosphamide, winkristin aanee prednisone kinwa prednisolone) asey sambodhale jaate.
dushparinam aanee guntagunt.
heey mishran samanyatah changle sahan kele jaate. chemotherapy-prerit malmal aanee ultyansathi antimaticschi (jase qee ondancetron) aavashyakta asoo shakate aanee mesna deuun raktasravi cystities rokhala jaato. allopesia (cases galane) hii samanya baab aahe.
neutropania samanyatah chakratoon aathvadyat vikasit hoto. yaa kalat, anek chikitsak pegfilgrastim kinwa ciprofloxacin rogpratibandhak vaparachi shifaras karatat. jarr neutropenic kalavadhit taap aala, tarr neutropenic sepsisasathi tatadiche vaidyakeey moolyankan aavashyak aahe, kaaran neutrophilchi sankhya qamee asalelya rugnanmadhye sansarg vegane vadhu shakato.
tumourchya peshinchya jalad mrutyucha parinam asalelya tumour lysis syndromemule syndromemule hyperuricemiapasoon bachav karnyasathi allopurinol samanyatah rognivarak paddhatine saha-prashasit kele jaate.
itihas.
1993 madhye prakashit jhalelya eka mahattvapoorn abhyasane kapchi tulana itar anek chemotherapychya paddhatinshi kelee (udaa.jee. pragat naun-hodgkin lymphomasathi emm-bacode, promise-cytabom, macop-bii). chup heey sarvat qamee vishari parantu samaan parinamkarakta asalele aahar mhanoon udayas aale.
tathapi, 2012 madhye germanymadhye, bendamsteinne [aar-] chopla visthapit kele aahe aanee teey aalashi lymphoma (naun-hodgkin lymphomacha qamee aakramak upasanch) sathee pasantiche pahile upchar banale aahe.
[r]-chaup badal.
aakramak lymphomasasathi adhik prabhavi pahilya-ola chemotherapycha aahar vikasit karnyasathi, kahee sanshodhakanni manak [aar]-chop aaharat bharr ghalanyacha prayatna keela.
chemotherapychya matra vadhavun [aar]-chop aaharpaddhatichi parinamkarakta aanakhi sudharanyache prayatna dekhil karnyat aale. yaa paddhatila [r]-uchch-chaukh asey mhatale gele. tathapi, adhik vishaktata aanee kharch vadhavat asatana, pramanit-matra [aar]-choipapeksha adhik parinamkarakta darshavili nahee.
[aar]-chopchi parinamkarakta sudharanyacha prayatna karnyasathi, kahee sanshodhakanni chemotherapy atishay uchch matreparyant vadhavanyacha prayatna keela, pratyek chakrat autologus stame seela samarthanachi aavashyakta hotee. tyaa aaharatil matra eka chakratoon chakratoon chakrat vadhavanyat aalya. yaa aaharala [aar]-megachop asey mhatale jaat asey. parantu punha, asha vadhimule vishaktata vadhavtana parinamkarakta sudharat nasalyache disun aale.

