
eff. aii. emm. 210bii

eff. aii. emm. 210bii. heey eka januk aahe jeey homo sepiyansmadhye eff. aii. emm. 210bii. prathinala sanketikrut karate. utkrantichya sampoorn itihasat teey sanrakshit kele gele aahe aanee manvi shariratil anek uutinmadhye teey atyant vyakt kele jaate. eff. aii. emm. 210bii. chey prathamik sthan endoplasmic reticulum aahe.
januk.
locus.
pham210bii heey gunasutra 20 chya adhik strandver, tantotant 20q13.2 varr aadhalate. heey januk lambit 9,749 kshar aahe, jeey 192 amino acid prathinanshi sambandhit aahe.
upnamanche.
paryayi navanmadhye see20orph108, kalpanik prathine lock116151, dj116h4.1 aanee 5aii3 yancha samavesh aahe.
emm. aar. aine. aii.
eff. aii. emm. 210bii. chey 2 dnyat splies prakar aahet, jyanna aupcharikpane eff. aii. emm. 210bii-001 aanee eff. aii. emm. 210bii-002 mhanoon olakhale jaate. eff. aii. emm. 210bii-001 lambimadhye 3 exon aahe, tarr eff. aii. emm. 210bii-002 heey 2 exon aahe.
prathine.
sarvat lamb purvavarti prathine lambimadhye 192 amino acid aahet. aanvik vajan 20.4 keey. dii. ell. aahe aanee samvidhyut bindu 10.8 aahe.
rachana.
prathamik rachana.
79 vya sthanavar 4 avasheshancha 1 sakaratmak aavesh aahe. uchch gunank asalela transmembrane kram 99-123, vhee. jee. vhee. ess. ell. jee. ess. jee. jee. ess. jee. jee. jee. jee. jee. jee. jee. aay. emm. sthananvar upasthit asato.
vhee. vhee. ess. ess. jee. vhee. endoplasmic reticulum retension signal (paak) 187-191 sthananvar upasthit asato.
duyyam rachana.
bahutansh rachana alfa helisesani banaleli aahe. majhya phayar 2 chya andajanusar, 61 takke prathine alfa helices tayar karatat aanee 28 takke transmembrane vibhag tayar karatat. transmembrane topologycha tapshilvar nakasha khalee darshavila aahe.
trutiyak rachana.
aay-tasserne khalee darshavilyapramane pham210beeche dumadane hoil assa andaj vartavala.
upkoshikeey sthan.
pham210bii prathinanche prathamik sthan endoplasmic reticulum aahe. amino aesidchya kramamadhye see-terminsjaval endoplasmic retension signal paak asato. done transmembrane kshetra aahet, jeey anek paddhatinni nishchit kele gele aahet aanee punha pushti kelee gelee aahe. teey khaleel anuvadanantarchya badalalelya pratimet thalakpane dakhavale aahet.
anuvadanantarche badal.
pudhil sankalpanatmak anuvadat anuvadanantar apekshit badal sadar kele aahet. badalancha andaj motifscandware vartavala gela aanee nantar adhik tapshilvar shodh ghetala
aadhalalelya badalanmadhye propeptide clevage sites, see-manocillation sites, galnack oo-glycosylation sites, lycine glycation sites, phosphorylation sites, coronavirus 3 see sarkhya proteinage clevage site aanee jee. pii. aay. sudharana site yancha samavesh aahe.
samarupata.
eff. aii. emm. 210bii. sathee eka mahattvachi paralog mhanje eff. aii. emm. 210aii. sastan prani, sarpatanare prani, pakshi, aprushthavanshi, maase, ubhaychar, trichoplax aanee burshi yaa sarvanmadhye ortholog aanee durchya samarupata aadhalalya aahet.
utkrantivadi itihas.
januk kutumbacha aakar done aahe aanee tyat pham210aii aanee pham210bii yancha samavesh aahe. jevha vanaspati proteestapasoon vegale hotat tevha janukanchi nakkal jhalyache disate. sarvat durcha ortholog aadhalala too populus trichocarpa hota, jyala black cottonwod trii asehi mhanatat. khalee asalele mull nasalele jatijanya vruksh heey vichalan darshavite. zadatil serve jeev vareel ortholog tablemadhyehi aadhalu shakatat.
abhivyakti.
pham210bii heey "homo sapiens" madhye sarvatra vyakt kele jaate. heey vikasachya pratyek tappyat aanee stun, greevey, yakrut, fuffuse, andashay aanee swadupindachya arbudansah anek dhokyat aalelya aarogya avasthanmadhye vyakt kele jaate.
elon brain atlus.
hii pratima elon brain etalasmadhun ghenyat aalee hotee aanee mashachya mendut eff. aii. emm. 210bii. chee abhivyakti darshavate.
yaa pratima cerebellumchya sagital katmadhil eff. aii. emm. 210bii (davikade) chya abhivyaktichi tulana dopamine beeta hydroxylase (ujavikade) shhee karatat.
bhoo-profile.
khaleel pratimet dengue taap asalelya rugnanmadhye kinwa barey jhalelya rugnanmadhye pham210beachii januk abhivyakti aahe. nilya thipkyanvarun disalyapramane, nirogi niyantranachya tulanet raktasravi taap aanee taap anubhavananya rugnanmadhye eff. emm. 210bii. chee shreni qamee jhaali aahe.
khaleel pratimet gambhir jivanu pneumonia, gambhir influenzae aanee jyanna influenzachi lus midali aahe asha rugnanmadhye eff. aii. emm. 210bii. chee januk abhivyakti aahe. pratimet disalyapramane, gambhir jivanu pneumonia asalelya rugnanmadhye pham210bii heey shreneet qamee aahe aanee jyanna influenzachi lus midali aahe tyanchya tulanet gambhir influenzae asalelya rugnanmadhye teey aanakhi qamee aahet.
parasparsanvadi prathine.
khaleel prathine pham210bishii parasparkriya karnyasathi nishchit kelee gelee. tyancha parasparsanvad effinity capture aanee maas spectrometric paddhatindware nirdharit keela gela. yaa prathinanchya karyache vishleshan karoon, eff. aii. emm. 210bii. chya karyabaddal adhik antardrushti dilee jaau shakate.