charles vacantee

charles alfried "chuck" vacantee (janm 1950) heey ootee abhiyantriki aanee stame selsache sanshodhak aahet aanee harvard vaidyakeey shalet anaesthesiology vandam/covino pradhyapak aahet. teey massatusates vidyapithatil aanee brigham aanee mahila rugnalayatil bhulvichedanshastrache majee pramukh aahet, jeey aata nivrutt jhaale aahet.
too vacantee mausasathi olakhala jaato, linda griffith aanee joseph uptonne tayar kelela under, tyachya pathivar manvi kanasarkhe cartilage aakarache aanee stap salesveril done mage ghetalelya lekhanpaiki pahilya lekhakacha varishtha lekhak mhanoon, tyachya bhavane aanee swatah prastavit keleli sankalpana aanee haruko obokata saha-lekhak.
karkird.
vacantine creiton preparatory highschoolmadhun padvi prapt kelee, bii.aaa. 1968 madhye creiton vidyapithatun, aanee tyanche emm.dii. 1975 madhye nebrasca vidyapithatil vaidyakeey mahavidhyalayatun, aanee nantar 1978 madhye vaidyakeey kendra rugnalayatil (aata vermont vaidyakeey kendra vidyapith mhanoon olakhale jaanare) vaidyakeey kendra rugnalayat tyanche shalyachikitsatmak prashikshan aanee nivas purn kele. tyanchya bhavansah, tyanna 2002 madhye varshatil majee vidyarthi mhanoon naav denyat aale aanee 2005 madhye kretankadoon tyanna majee vidyarthyanche kamgiriche prashastipatra midale.
vacantee heey emm. aay. tii. aanee mulanchya boston rugnalayat sanshodhan sahyogi aanee massatusates general rugnalayat bhulatadnya hote. teey massatusates vaidyakeey kendra vidyapithatil bhulvichedanshastrachya vibhagache adhyaksh jhaale aanee massatusates vaidyakeey vidyalay vidyapithat bhulvichhedanshastra aanee shastrakriyeche pradhyapak jhaale. 2002 madhye teey alfa-alfa alfa sathee nivadoon aale.
september 2002 madhye, vacantee brigham aanee mahila rugnalayat sameel jhaali, sayman jailmanchya jaagi anaesthesiology, perioperative aanee vedna aushadh vibhag adhyaksh mhanoon. step selchya vadanantar, rikti brigham aanee mahila rugnalayatil vibhagiy adhyakshapadacha rajinama deela aanee 1 september 2014 pasoon eka varshacha vishranti ghetala, nantar 2015 madhye nivrutt jhaala.
tyanni 200 hoon adhik lekh, saransh aanee pustake prakashit kelee aahet. tyanni ootee abhiyantriki sansthechi saha-sthapana kelee aanee stame selshee sambandhit anek paytant tyanchyakade aahet. teey 2007-8 madheel society auph ekedemik anaesthesiology adhyaksh hote.
ootee abhiyantriki.
tyachi parshvabhoomi bhulvidnyanachi asali taree, 1980 chya dashakachya uttaradhat, jyane yakrut punarjananavar kaam karat asalela tyacha bhau joseph, jyala jaya asehi mhanatat, tyachyasobat vacantine ootee abhiyantrikimadhye kaam karnyas suruvat kelee.
1989 madhye, vacantine pahilyanda biodegradable scaffoldver manvi upasthi inn vitro vadhavali; heey kaam 'top journal' madhoon nakarle gele kaaran tyache 'konatehi vyavharik parinam naheet' asey mhatale gele hote. yamule aashcharyachakit houn, houn riktata gola jhaali qee sarvat katheen cartilagenous pratisthapan mhanje qaan. tantranmadhye sudharana kelyanantar aanee emm. aay. tii. yethe robbert langerchya kamavar kaam kelyanantar, 1997 madhye massatusates vidyapithatil vacantee aanee aanee vadgrastapane aanee madhyamanchya mothya lakshasah, polymer scaffold aanee gayichya gudghyachya chaundrocyte peshincha vapar karoon, nagna undaranchya mageel bajus manvi kanasarkhi upasthi rachana vikasit kelee-jyala iyarmaus, auriculosaurus kinwa vacantee maus asey mhanatat.
vacantee aanee tyacha bhau joseph yanni tyach tantracha vapar karoon 12 varshanchya seane mccormack yaa mulasathi chhatichi plate vadhavali, jyacha janm tyachya hrudayavar aanee fuffusavar upasthi kinwa hadanshivay jhaala hota. 1998 madhye, massatucetsmadhil vacantichya netrutvakhalil sanghane, jyacha angatha chiralela hota asha raul mursia yaa mansasathi, pravalanchya farshicha vapar karoon, angathyachya badalache haad vikasit kele. eff. dii. aii. neey yaa kamala manjuri dilee hotee, parantu tyanni upasthi aanee snayu vadhavanyasahi manyata dilee nahee. 14 varshanchya mulisathi vacantine eka naveen shwasanalikadekheel vikasit kelee.
vacantee mhanatat qee tyanni 1991 madhye anga badalanyachya sandarbhat ootee abhiyantriki hii sandnya tayar kelee, jaree tee purvi itar vaparasathi vaparali gelee hotee aanee tyanchi nakkal vadgrast aahe (udaharanarth, hii sandnya 1984 madhye netra shalyachikitsakane tyach sandarbhat vaparali hotee).
stame peshi.
bijkanasarkhya peshi.
jyala nantar step cells ('pluripotensiche uttejak-prerit adhigrahan') mhatale jaeel yachee kalpana vacanticadoon aalee, jyala tyacha bhau martin, jyala shaheed mhanoon olakhale jaate, asey vatat hote qee praudh sastan pranyanchya uutinmadhye lahan pluripotent peshi asatat jyaa ootee jakhami jhalyavar kinwa tanalyavar sodalya jaat asat.
charlesne 1996 madhye nebrascahoon aaplyabarobar kaam karnyasathi jaanyasathi eka pathologist shahidala patvoon dile hote aanee tyane shahidanna vicharale qee, sanvardhanat lavkar lavkar pramanit praudh peshi aanee garbh peshi, jyaa vaparnyasathi vadgrast aahet, tyanna paryay mhanoon praudh stame peshi shodhata yeteel qaa? tyachya bhavachya daun syndromever upchar karnyachya ichchemule vacantila stame selsvar kaam karnyasathi prerit kele gele.
shahidanni pratham undaranchya menduchya uutinmadhil lahan mool peshi olakhalya jyaa tyane kapalya hotya aanee lahan nalikanmadhun jabardastine kelya hotya. pahilyanda tyanni tyanchi olakh patavali tevha teey durchitravanichya chamoola nikal dakhavanyasathi dabavakhali kaam karat hote aanee anek sahkari nikalambaddal sanshayi hote. tyanni 2001 madhye yaa "bijkanasarkhya peshinche" varnan karnare kaam prakashit kele aanee nondavale qee yaa peshi anek divas anoxic sthiteet tiku shakatat aanee tyaa vegalya bijkanasarkhya peshinmadhun swadupind aanee fuffusansah vividh ootee vadhavanyas saksham aahet.
step peshi.
charles harwardla gela tevha tyane yaa peshinvar kaam karane suru thewale, jyat vaksh shalyachikitsak koji kojima hyasah, jyane tyanna fuffusachya uutinmadhye olakhale. vacantine 2008 pasoon harvard yetheel tyachya prayogshalet haruko obokata yaa padvidhar vidyarthyachi bharati kelee aanee tine bijkanasarkhya peshinvar kaam kele aanee tyanna tichya prabandhatil kendrabindu banavale; obokata yanni peshi terratoma madhye vadhavane sadhya kele, jeey vacantine kele navhate.
charlesne nantar yaa siddhantala parishkrut kele qee tanav kinwa dukhapat hii sharirik peshinmadhye pluripotensichya vikasas pratyakshat chalana deu shakate aanee suruvatila hii kalpana obokata pasoon thewali. 2010 madhye floridamadhye jhalelya parishadet tyane pahilyanda obokata aanee masayuki yamato yanna haah prastav mandala; yamato swatantrapane tyach nishkarshavar pohochala hota.
riktine poost-doctor mhanoon obokata chaloo thewala. tyanni suruvatila jakhami peshinsathi urjecha srot mhanoon aii. tii. pii. chaa vapar prastavit keela. obokata yanni sudharit parinamancha arth, aii. tii. pii. dravanachya qamee pii. etch. mule hoto, dahak mhanoon tyache gunadharm mhanoon navhe. tyanantar tee japanla paratali aanee tine heey kaam kayamche chaloo thewale. yoshiki sasaichya sahkaryane obokata yanni stame seela reshechya vikasatoon vacantila vagalale.
prakashan.
vacantine julai 2012 madhye society auph cardiovascular anaesthesiologist conferencemadhye heey parinam sadar kele aanee nantar janewari 2014 madhye 'nechar' yaa niyatkalikane done lekh prakashit kele jyat asey suchavale gele qee eka sadhya aaml upcharamule undaranchya rakt peshi pluripotent houu shakatat.
boston globe" neey nondavale qee "tyacha shodh hii eka aathvan karoon denari gosht aahe qee vidnyan jitke vishesh aahe titkech, kadhikadhi thodese adnyan haah eka sadgun asoo shakato. stame-seela tadnyane kadachit 1990 chya dashakachya uttaradhapasun riktata suru asalela prayog karnyacha prayatna karanyachi kadhihi kalji ghetali nasati."matra, tyachya harvard chamoola yaa kamachya utpattiche yogya shrey midalele nahee, asey vacantila vatale.
vacantine dawa keela qee februvarine manvi tvachechya fibroblast peshinmadhil parinamachi pratikruti tayar kelee aahe aanee "aamhala vishvas aahe qee konatyahi kharab jhalelya kinwa roggrast uutinchi durusti karnyachya prayatnandarmyan sharirat nemke hetch ghadate". 2012 madhye, eka rugnachya autologus peshincha vapar karoon, tyane punarsthit shwasanalikela vadhavanyasathi yaa tantracha vapar kelyache vacantine sangitale.
ghotalyacha.
tathapi, yaa kshetratil itar sanshodhakanni parinam punha tayar kele naheet aanee peshinchya hiravya rangachya chamkamule pluripotency soochit hote asey george delichya padvidhar vidyarthyane vacantichya prayogshalet mrut peshinmadhun swayam-pratidipti mhanoon samarthan dile.
julai 2014 madhye, recanchya tapasanit, hii mahitee banavat asalyache nishpann jhalyanantar, donhi mukhya lekh mage ghenyat aale. akheris maghar ghenyas sahmati darshavilyanantarhi, vacantee mhanale qee "pluripotency (step) peshi ghatanechya uttejana-prerit sampadanachya astitvavar shanka ghenari konatihi mahitee nahee."johnn rasco aanee carl power yanni" "daad guardian" "madhye lihile qee jaree vacantiche sahkari obokata aanee reconmadhil itaranni stap selchya magharsathi bahutek dosh ghetala asala, taree vacantine swatah parinamanchi nakkal karnyas saksham asalyacha dawa karoon aanee march aanee september 2014 madhye stap cells tayar karnyasathi 'pakakruti' (tyachya sanketsthalavar) pradan karoon, jyaa itar konatehi sanshodhak punarutpadit karoo shakale naheet, tyadvare" "swatah obokatapramanech pratikrutichya samasyeche gondhal ghalanyasathi jawaljawal barech kahee kele".
vacantichi prayogshala bund jhaali aanee stap ghotalyanantar 2015 madhye teey nivrutt jhaale, parantu 2016 paryant teey tanav-prerit pluripotensichya tattvavar vishvas thevat rahile. janewari 2017 madhye, tyanni amerikechya paytant karyalayala nakarlelya step seela patentver punarvichar karnyas sangitale aanee yaa davyache samarthan karnyasathi naveen prayog sadar kele.
vaiyaktik jeevan.
vakanticha janm omaha, nebrasca yethe jhaala, too aath mule asalelya cicilian kutumbatil dusra bhau hota; tyache ivadil charles jeey. vacantee aanee joenne keey vacantee (nee franco). tyache vadil creiton vidyapithat dantchikitseche pradhyapak hote (jeey nantar rikt dekhil jhaale) aanee ruut canal shastrakriyeche suruvatiche karmchari hote aanee tyachya aaeene lagn hoiparyant vidyapithat rasayanshastracha prii-maid abhyas keela. 1994 madhye hrudayavikarachya zatkyane tyachya vadilanche nidhan jhaale aanee charles yannahi hrudayavikarachya samasya aalya aahet.
tyala lahanpanapasunach abhiyantrikimadhye rus hota aanee upkarnanmadhye rus asalyamule too bhulatadnya banala. charles junya motorcycle gola karato aanee punarsthapit karato.
bhawand.
tyanna chaar bhau aanee teen bahini aaheth tyancha motha bhau dow. joseph pii. rikti (ootee abhiyantrikichya janakanpaiki eka manale jaanare) aanee tyanche dhakate bhau dow. martin pii. rikt aanee dow. francis ex. rikt asalele serve vaidyakeey sanshodhak aahet; teey "atishay spardhatmak" aahet aanee ektritpane, tyanna "ootee abhiyantrikiche pahile kutumb" mhatale gele aahe. tyacha dusra bhau carl yala daun syndrome aahe.

