tassy-see. aar. dii. 2 prathin kshetra

aanvik jivashastrat, tassy-see. aar. dii. 2 heey prathinanchya tassy kutumbat aadhalanare cysteine-samruddha dusare prathin kshetra darshavate. yaa kutumbatil sadasya pramukhyane tumour necrosis factor receptor super family, sadasya 13 bii (tassy) madhye aadhaltat aanee april aanee baaf yaa legandshee bandhanyasathi aavashyak asatat. tassy-see. aar. dii. 2 mhanje transmembrane sakriyak aanee camel interactor-cysteine samruddha domain 2.
karya.
tassy heey baff functionche nakaratmak niyamak mhanoon karya karate kaaran tassy abhivyakti qamee jhalyamule bii lymphocytes atirikt utpadan hote, joou eka prakarcha navachya raktapesheencha prakar aahe joou sansargapasun sanrakshn karato. cytokinesche anukram, karyatmak aanee sanrachanatmak samanatechya aadhare kutumbat vargikaran kele jaau shakate.
tumour necrosis factor (tii. aine. eff.) (tii. aine. eff.-alfa kinwa cashectin mhanoonahi olakhale jaate) heey eka cytotoxin aahe jeey monocytes navachya navachya rakt peshinchya eka prakaratoon tayar kele jaate. yamule tumour regression, septic shock aanee cashexia hoto asey manale jaate. prathinanche asamanyapane lamb aanee asamanya sanket kramasah prohormone mhanoon sanshleshan kele jaate, jeey paripakv sravit cytokinemadhye anupasthit asate. amino acidcha eka lahan hydrophobic taana lipid bilayersmadhye prohormonela langada ghalanyas madat karato. propeptidechya vichchedananantar samprerakache paripakv prathine aanee anshatah prakriya kelele swaroop donhi stravale jaatat.
tii. aine. eff. chee anek vegvegali kutumbe aahet, parantu hii serve cytokines homotremeric (kinwa ell. tii.-alfa/beetachya babatit heterotremeric) sankul tayar karatat asey disate jeey tyanchya vishisht receptorsdware olakhale jaatat. tassy haah tumour necrosis factor receptor super familicha sadasya aahe aanee bii peshi karyache niyamak mhanoon tyachi mahattvachi bhoomika aahe. tessy april aanee baaf yaa done legandsla bandhate, jyashi teey uchch aatmiyata balgatat aanee tyachya bahya koshikeey pradeshat cysteine-samruddha done kshetra (see. aar. dii.) asatat.
rachana.
tassy-see. aar. dii. 1 heey paryayi splicingdware aine-terminal cysteine samruddha kshetra kadhoon takoon tassy-see. aar. dii. 2 tayar karate. heey lahan swaroop legand-prerit peshi sanket denyas saksham aahe aanee dusra see. aar. dii.
ektyane (tassy-see. aar. dii. 2) donhi legandsasathi purn aakarshan asate.
legands.
legands heey prakar II transmembrane prathine cytokines aahet jyancha rogpratikarak peshinvar vividh parinam hoto, jyat eka mhanoon karya karane samavisht aaheh
april (jyala tii. aine. ess. eff. 13aii, unch-2 aanee tii. aar. dii. ell.-1 asehi mhanatat) haah eka tii. aine. eff. legand aahe joou kahee gathindware atiprabhavit hoto.

