
nucleoprotein

nucleoproteins hii nuclic acids (ektar dii. aine. aii. kinwa aar. aine. aii.) sanyugmit prathine aahet. vishisht nucleoproteinsmadhye ribosomes, nucleosomes aanee vishanujanya nucleocapsid prathine yancha samavesh hoto.
sanrachana.
nucleoproteins sakaratmak charge asatat, jyamule nakaratmak charge asalelya nucleic acid sakhalyanshi parasparkriya sulabh hote. anek nucleoproteinschya trutiyak sanrachana aanee jaivik karye samajoon ghetali jaatat. nucleoproteinschy sanrachana nishchit karnyasathichya mahattvachya tantranmadhye ksh-kiran vivartan, anoo chumbakeey anunad aanee cryo-electron sukshmadarshakacha samavesh hoto.
vishanu.
vishanuche genomes (ektar dii. aine. aii. kinwa aar. aine. aii.) vishanuchya capsidmadhye atyant ghattapane bharalele asatat. tyamule anek vishanu heey nucleoproteinschy sanghatit sangrahapeksha thode adhik asatat aanee tyanchya bandhanichi thikane aatalya dishene nirdesh karatat. sanrachanatmakdrushtya vaishishtyapurn vishanujanya nucleoproteinsmadhye influenzae, rabies, ibola, buniumwera, sclalenberg, hajara, crimean-kongo raktasravi taap aanee lassa yancha samavesh hoto.
deoxyribonucleoperciotriopote.
deoxyribonucleoriopotriope (dnp) heey dna aanee prathinanche eka sankul aahe. prototypical udaharane mhanje nucleosomes, complexes jyamadhye genomic dna heey eukariotic seela nucleusmadhye aath histone prathinanchya samoohanbhovati gundaloon chromatin tayar kele jaate. shukranunmadhye utpattichya darmyan protamines histoneschi jaaga ghetat.
karye.
sarvat vyapak deoxyribonucleoperciotriopote heey nucleosome aahet, jyamadhye ghatak nuclear dna aahe. dii. aine. aii. saha ektrit prathine histones aanee protamines aahet; parinami nucleoproteins gunasutranmadhye sthit asatat. asha prakare, sampoorn gunasutra, i.eae. eucariotsmadhil chromatinemadhye asha nucleoproteins asatat.
eukariotic peshinmadhye, dii. aine. aii. haah chromatin navachya atyant ghanroop nucleoprotein sankulatil histone prathinanchya sumare samaan vastumanasaha sambandhit asato. yaa prakarchya sankulatil deoxyribonucleoperciotriopote parasparsanvad sadhun eka bahuprathine niyamak sankul tayar karatat jyamadhye madhyavarti dii. aine. aii. loop kelele asate kinwa jakhameche asate. deoxyribonucleoperciotriopote dii. aine. aii. pratikruti aanee pratilekhan niyantrit karnyat sahbhagi hotat.
deoxyribonucleoperciotriopote heey samaroop punarsanyojanamadhye dekhil samavisht asatat, jee dii. aine. aii. chee durusti karanyachi prakriya aahe jee jawaljawal sarvatrik disate. yaa prakriyetil madhyavarti madhyavarti payari mhanje dii. aine. pii. philament tayar karnyasathi single-stranded dii. aine. aii. saha recombinage prathinanchya anek pratincha parasparkriya. yaa prakriyet vaparale jaanare punarsanyojne archaea (rada punarsanyojne), jivanu (rika punarsanyojne) aanee yukariyotsadware yeastpasoon manavanmadhye (reed 51 aanee dii. emm. see. 1 punarsanyojne) tayar kele jaatat.
ribonucleoproteins.
ribonucleoprotein (aar. aine. pii.) heey ribonucleic aaml aanee aar. aine. aii.-binding prathinanche eka sankul aahe. heey sankul anek mahattvachya jaivik karyanmadhye avibhajya bhag bajavtat jyat pratilekhan, anuvad aanee januk abhivyaktiche niyaman aanee aar. aine. aii. chya chayapachayache niyaman karane yancha samavesh aahe. aar. aine. pii. ess. chya kahee udaharananmadhye ribosome, telomeres enzyme, walt ribonucleoproteins, aar. aine. aii. ess. pii., etch. aine. aar. aine. pii. aanee small nuclear aar. aine. pii. ess. (ess. aine. aar. aine. pii. ess.) yancha samavesh hoto, jeey prii-emm. aar. aine. aii. splicingmadhye (spliciosome) guntalele aahet aanee nucleoluschya mukhya ghatakanpaiki aahet. kahee vishanu heey sadhe ribonucleoproteins asatat, jyat aar. aine. aii. chaa keval eka renu aanee anek samaan prathinanche renu asatat. itar mhanje ribonucleoprotein kinwa deoxyribonucleoriopotriotus sankul jyamadhye anek bhinn prathine asatat aanee apavadatmakapane adhik nuclic acid renu asatat. sadhya, aar. see. ess. bii. prathine deta bankmadhye (pii. dii. bii.) 2000 peksha jaast aar. aine. pii. ess. aadhalu shakatat. shivay, prathine-aar. aine. aii. interfaces deta bases (pii. aar. aay. dii. bii.) kadey pii. dii. bii. madhoon ghetalelya detachya aadhare aar. aine. aii.-protein interfacevaril mahiticha sangrah asato. prathine-aar. aine. aii. interfacechi kahee samanya vaishishtye dnyat sanrachananchya aadhare shodhun kadhali gelee. udaharanarth, ess. aine. aar. aine. pii. madheel aar. aine. pii. chya aar. aine. aii.-binding prathinanmadhye aar. aine. aii.-binding rachana asate. yaa rachneteel sugandhit amino acid avasheshanmule aar. aine. aii. saha parasparsanvad jodala jaato. aar. aine. aii.-bandhani prathinanchya helical bhagatil lycine avashesh nucleic acids parasparkriya sthir karnyas madat karatat. heey nuclic acid bandhan sakaratmak lycine bajuchya sakhalya aanee nakaratmak nuclic acid phosphet pathichya hadanmadhil sthir vidyut aakarshanadvare majboot hote. yavyatirikt, aar. aine. pii. ess. chey sanganakeey swaroop tayar karane shakya aahe. aar. aine. pii. sanrachana mojanyachya sanganakeey paddhati prayogik paddhatinpeksha qamee achook asalya taree, tyaa sanrachaneche eka sthool model pradan karatat jyamule mahattvapoorn amino acid aanee nucleotide avasheshanchya olakhicha andaj lavta yeto. ashee mahitee aar. aine. pii. chey ekoon karya samajoon ghenyas madat karate.'rnp' haah ribonucleoprotein kanancha dekhil sandarbh gheu shakato. pratilekhanantarchya niyamanasathi ribonucleoprotein kann heey swatantra antakoshiy kendra aahet. heey kann influenzae yaa vishanuchya pratikrutimadhye mahattvachi bhoomika bajavtat. influenzae vishanujanya genome haah vishanujanya nucleoproteinshy bandhalelya nakaratmak-sanvedana aar. aine. aii. chya sankuladware tayar jhalelya aath ribonucleoprotein kananni banalela asato. pratyek aar. aine. pii. sobat aar. aine. aii. polymerase complexes asate. jevha nucleoprotein vishanujanya aar. aine. aii. laa bandhate, tevha teey nucleotide payacha pardafash karnyas saksham asate, jyamule vishanujanya polymerasela aar. aine. aii. lipyantar karata yete. yaa tappyavar, ekada vishanu yazman peshimadhye pravesh keela qee too pratikrutichi prakriya suru karnyasathi tayar hoil.
anty-aar. aine. pii. pratipinde.
anty-rnp pratipinde hii 'mishra sanyoji uutinchya roga' shhee sambandhit svayampratibandhak aahet aanee lupus erythematosuschya sumare 40 takke rugnanmadhye dekhil aadhaltat. done prakarchya anty-rnp pratipindejcha sjogren syndromeshy jawalcha sambandh aaheh ss-aii (aarao) aanee ss-bii (laa). ess. aine. aar. aine. pii. viruddha svayampratibandhakanna anty-smith antibodies mhanatat aanee teey zopesathi vishisht asatat. yuu-1-rnpchya lakshaniy patalichi upasthiti itar anek ghatakanchya sanyogane aadhalalyavar emm. see. tii. dii. chey sambhavya soochak dekhil dete.
karye.
ribonucleoproteins sanrakshanachi bhoomika bajavtat. peshimadhye mukt aar. aine. aii. renu mhanoon emm. aar. aine. aii. kadhihi udbhavat naheet. teey nehmi ribonucleoproteins sambandhit asatat aanee ribonucleoproteins complexes mhanoon karya karatat.
tyach prakare, nakaratmak-strand aar. aine. aii. vishanuche genome mukt aar. aine. aii. renu mhanoon kadhihi astitvat nasatat. ribonucleoproteins tyanchya janukanche aar. aine. aii. ess. pasoon sanrakshn karatat. nucleoproteins heey bahutekda vishanunsathi pramukh pratijan asatat kaaran tyanchyat taana-vishisht aanee gut-vishisht pratijan nirdharak asatat.