peptidial hastantaran

peptidil transferage heey eka eminoaciltransferase () tasech ribosomeche prathamik utsechak karya aahe, jeey prathinanchya jaivasanshleshanachya anuvad prakriyedarmyan tranancha vapar karoon shejarchya emino aesidmadhye peptide bandh tayar karate. peptidial hastantaran pratikriyesathiche thurr done tii. aar. aine. aii. renu aahet, eka vadhanari peptide sakhali dharan karnara aanee dusra sakhalimadhye jodale jaanare amino aaml dharan karnara. peptidial sakhali aanee amino aaml heey yaa trinanchya see. see. aii.-3 'tokanvar oo anooshi ester bandhandware tyanchya sambandhit trinanna jodalele asatat. peptidil transferage heey eka enzyme aahe jeey prathin sanshleshanat polypeptide sakhali vadhavanyasathi amino acid avasheshanchya jodanila utprerit karate. heey mothya ribosomal upaghatakat sthit aahe, jithe teey peptide bandh nirmitila utprerit karate. teey purnapane aar. aine. aii. neey banalele aahe. peptidial hastantaran kendratil ribosome-baddh peptidial trana aanee eminoacyl tranachya see. see. aii. tokanmadhil sanrekhan yaa pratikriyanna utprerit karnyachya tyachya kshamatet yogdan dete. hii pratikriya nucleophilic visthapanadvare hote. eminoacyl trancha amino gut peptidial tranchya antim carboxyl gatavar hallah karato. peptidil hastantaran kriya rayabosomdware kelee jaate. peptidil hastantaran kriyakalap konatyahi ribosomal prathinandware madhyasthi karat nahee tarr ribosomal aar. aine. aii. (aar. aar. aine. aii.) yaa raibozaimdware madhyasthi kelee jaate. ribosimes heey ekmev enzymes aahet jeey prathinanni navhe tarr ribonucleotidesne banalele asatat. itar serve enzymes prathinanni banalele asatat. haah aar. aine. aii. avashesh haah aar. aine. aii. jaagtik gruhitkala samarthan denara sarvat mahattvapoorn purava aahe.
peptidial hastantaran heey keval anuvadapurate maryadit naheet, parantu yaa karyasah tulanene qamee utsechake aahet.
karya.
peptidial transferage hii tyachi sakriyatechi urja qamee karoon pratikriyecha veg vadhavate. tee pratikriya ghadanyasathi yogya disha pradan karoon heey karate. peptidial hastantaran nikatata pradan karate, mhanje teey goshtila jawal aanate, parantu tee paryayi yantrana pradan karat nahee. tyaeivaji, teey yogya thurr abhimukhata pradan karate, jyamule vidyaman yantrana udbhavanyachi sambhavyata vadhate.
yantrana.
parshvabhoomi.
ribosomal sanrachanet teen bandhan sthale asatat jee pii site, eka site aanee eae site aahet. eka site hii eminoacyl site aahe kaaran eka sitemadhye jeey yete teey eminoacyl trana aahe. sanrachanet eka amino acid avashesh asato joou ekhadya jageshi jodalelya ester linkejmadhye asato aanee tethe eka mukt amine asate. peptidil site asalelya pii sitewar, eka tii. aar. aine. aii. jodalela asato. heey lakshat ghene mahatvache aahe qee peptidial hastantaranachya pratyek chakrachya suruvatila tumhi nehmi pii sitewar sitewar peptide sakhalisah tii. aar. aine. aii. neey suruvat karata. ekada asey jhaale qee eminoacyl trana ekhadya jageshi bandhale jaau shakate.
vastavik yantrana.
yantranechya sandarbhat, ekhadya thikani asalele amine pii sitevaryl ester karbanvar nucleophilic hallah karnar aahe. jevha nucleophilic hallah hoto, tevha eka tetrahedral madhyavarti tayar keela jaeel. peptidial hastantaranachya sakriy thikani, panyache avashesh asatat. jevha chatushkoniy madhyavarti tayar hote, tevha auxiyaniyanavar aata nakaratmak charge asato kaaran oxygenmadhye eka atirikt electron asato. panyavaril hydrogenavar aanshik sakaratmak prabhar asato, joou tetrahedral auxianian madhyavarti sthir karato. tyanantar kaay hoil teey mhanje tetrahedral madhyavarti kosalel aanee carbonyl bandhamadhye sudharana hoil jyamule baher padnara gut gamavel-mhanje tyala jodaleli tii. aar. aine. aii. asaleli pii. site raiboj ring asel. baher padnara gut sodalyavar, proton panyatoon amoort hoil jyamule done mukhya hydroxyl gatanmadhun proton amoort hoil aanee ektya jodya amino aesidchya naveen amainmadhun proton amoort kartil. yantrana purn jhalyanantar, eka gair-acelated tii. aar. aine. aii. pii. sitewar raheel aanee atirikt amino acid vyatirikt sampoorn vadhanari polypeptide sakhali serve eka sitevaryl tii. aar. aine. aii. chya teen mukhya hydroxyl gatanshi ester linkejmadhye jodali jaeel.
pratijaivikanche lakshya.
khaleel prathine sanshleshan avarodhak peptidil hastantaran lakshya karatatah

