cube domain

 
cube domain heey utkrantivadi sanrakshit prathinanche kshetra aahe. cube domain (purak (purak, uegf, bii. emm. pii. 1 sathee) hii sumare 110 avasheshanchi sanrachanatmak rachana aahe jee jawaljawal keval bahya koshikeey aanee plazma puttle-sambandhit prathinanmadhye aadhalate, jyapaiki anek vikasatmakpane niyantrit aahet. hii prathine purak sakriyakaran, vikasatmak rachana, uutinchi durusti, akshatantu margadarshan aanee angiogenesis, peshi sanket, garbhadhan, haemostasis, jaljal, neurotransmission, receptor-madhyasth endocytosis aanee tumour dadapane yasah vividh karyanmadhye guntaleli asatat. anek shavakyukt prathine hii merops peptidase kutumbanshi sambandhit sambandhit (estacin) aanee aanee (chimotrypsin) yaa peptidase aahet.
udaharane.
cube domain asalelya prathinanmadhye khaleel goshtincha samavesh hotoh
vareel prathinanpaiki anek prathinanmadhye calcium-bandhankari eae. jee. eff. kshetrandvare vikharalelya anek cube kshetransah utprerak kshetra asate.
shukranu haah shavak kshetra kutumbatil eka upavibhag aahe aanee sastan pranyanchya viryadravyacha eka pramukh ghatak aahe. shukranu heey 110-133 amino acid polypeptides aahet. shukranunchi bandhan kriya, udaa.jee. heprin aanee karbodkanshache bandhan, andakoshanchya prushthbhagavar prushthbhagavar glycoproteinvaril karbodkanshachya gatanshi shukranunche jodane vadhavanyat tyanchi madhyavarti bhoomika saksham karate. dukaranche, bailanche aanee stallionche shukranu tyanchya amino aesidchya anukramamadhye 40-98% samanata darshavtat aanee sarvanmadhye jawalchya cysteine avasheshanmadhye diasulphide bandh asato. sungadhi shimpadatil polypeptides paach jawalun jodalelya janukandware code kelele asatat. bowine shukranu heey janukanchya lakshaniy qamee sankhyevar avalambun asate aanee keval donach heey bowine seminal dravatil yaa prathinanchya abhivyaktishi sambandhit aahet. chimpanzi, kutre aanee manavanmadhye shukranunsathi anavashyak anuvanshik coding disun aale aahe. under aanee undaranchya dna madheel shukranu janukanshi sambandhit asalela pradesh konatyahi shukranu kodapasoon shoonya aahe. spermadecinschya abhivyakti aanee anuvanshik sanketikaranatil heey badal anuvanshik samgrimadhil utparivartan aanee vilopanacha parinam mhanoon janukanmadhil utkrantivadi samayojananmule disun yetat.
kahee cube domain heey oligomerization aanee/kinwa thurr aanee bandhan bhagidaranchya manyatemadhye sameel asalyache disate. udaharanarth, purak proteeaesmadhye, cube domain dimerisationmadhe madhyasthi karatat aanee lakshya prathinanchya kolejansarkhya pradeshanshi (udaa.jee. c1r/c1s sathee c1q). cube domenchya sanrachanet jailey-roll folds beeta-sandwich asate. jawaljawal serve cube kshetranmadhye chaar sanrakshit cysteine asatat jeey kadachit done diasulphide pool pool, (see1-see2 tayar karatat. karatat aanee nakasha 19 chya chya kshetranmadhye calcium-bandhan sthale aahet.
yaa kshetramadhye asalelya prathinanche sanketan sanketan manvi janukanmadhye khaleel goshtincha samavesh hotoh

