
marthe gautier

marthe gautier (; 10 september 1925-30 april 2022) hii eka french vaidyakeey doctor aanee sanshodhak hotee, jee gunasutrachya vikrutinshi rogancha sambandh shodhanyatil tichya bhoomikesathi prasiddha hotee.
shikshan.
marthe gautiyarne lahan vayatach balrogatadnyancha vyavasay shodhala. 1942 madhye tee tichi baheen poletsobat sameel jhaali, jee balrogatadnya honyachya uddeshane parismadhye tiche vaidyakeey shikshan purn karnar hotee. tine 'internet days hopitox dii parris' chee pravesh pariksha uttirn kelee aanee pudhil chaar varshe balrogatadnyanmadhye vaidyakeey anubhav midvinari intern mhanoon ghalavali.
1955 madhye tine robbert debre yanchya margdarshanakhali balrogatadnyanchya hrudayavikarachya vishayatil ticha prabandh sadar keela aanee tyacha bachav keela. tichya prabandhat streptococcus sansargamule sandhivatachya tapachya (sandhivatachya endocarditis) pranghatak prakaranchya vaidyakeey aanee sharirik vikarshastrachya abhyasavar laksh kendrit kele gele.
tyaveli francemadhil balrogatadnyanche prabhari asalele robbert debre yanni, done mukhya uddishtansah balrogatadnyanche hrudayshastratil dnyan prapt karnyasathi, gautier yanna harvard vidyapithat eka varshasathi shishyavrutti deu kelee. pahila mhanje sandhivatacha taap nirmulanasathi penicillincha vapar karane aanee kadhikadhi pranghatak hriday v raktavahinyasambandhi roganvar courtisones upchar karane; dusra mhanje navjat aanee lahan mulansathi janmajat hrudayroganche nidan aanee shastrakriyesathi eka vibhag tayar karane.
september 1955 madhye, gautier bostenla ravana jhaala. tichyasobat jeane icardy aanee jacks kavrur heey doghehi uttam vidwan hote aanee heey tighehi hopitox dii parisache pahile prashikshanarthi banale jyanna amerikesathi shishyavrutti denyat aalee. harvard yethe, tichya internshipchya kamanpaiki eka kaam seela kalcharmadhye kaam karnare prayogshala tantradnya mhanoon prashikshit hone heey hote. suruvatila tharavalelya done uddishtanvyatirikt, mahadhmanichya tukadyanpasun suru honanya fibroblastchya inn-vitro cultures midvinyasathi, gautier peshi sanwardhan tantradnya mhanoon ardhvel kaam karat hota.
bostenmadhye eka varsh rahilyanantar, gautier parisla paratala. darmyan, parismadhil bisetre rugnalayatil balrogatadnyanchya hrudayavikarachya sevetil tichi nokri tichya anupasthitit eka sahkanyala denyat aalee hotee. tathapi, teela kalale qee raymond turpinchya sanghat, trauso rugnalayat eka padd upalabdh aahe.
turpinche sanshodhan bahupadi lakshansamuchchayanvar kendrit hote, jyapaiki sarvat samanya mhanje trisomy, jeey bauddhik apangatva aanee aakarshastriy vikrutindware darshavile jaate. tyaveli, turpinne trisomichya gunasutra utpattichya gruhitkala pasanti dilee parantu francemadhye peshi sanvardhanasathi prayogshala navhati aanee manvi gunasutranchi sankhya 48 asalyacha andaj hota, parantu konatihi khatri navhati.
daun syndrome.
prayogshaletil peshi sanwardhan.
1956 madhye sweedenmadhil lund vidyapithachya jivashastradnyanni jaheer kele qee manavanmadhye nemke 46 gunasutra aahet. turpinne anek varshanpurvi trisomymadhil gunasutranchi sankhya mojanyasathi peshinchya sanvardhanachi kalpana prastavit kelee hotee. gautier alikadech armond-truso rugnalayat tyachya netrutvakhalil balrogatadnya gatat sameel jhaala hota aanee tine heey karnyacha prayatna karanyachi tayari darshavali, kaaran teela americet peshi sanwardhan aanee uutinvar daag ghalanyachya tantranche prashikshan denyat aale hote. daun syndrome asalelya rugnankadun teela uutinche namune denyas turpinne sahmati darshavali. atishay maryadit sansadhanansah gautiyarne francemadhye pahili 'inn vitro' peshi sanwardhan prayogshala sthapan kelee.
gunasutranchi ganana karnyasathi, gautiyarne sanyoji uutinmadhun midavalelya fibroblastver kaam kele, jeey sthanik bhool deuun midvane sope hote. jaree peshi sanvardhanache tattva sope asale taree, gautiyarsathi upalabdh asalelya adim paristhitit teey karya karnyasathi anek vyavharik adthale hote, jyanna prayogshaletil kachechi bhandi kharedi karnyasathi vaiyaktik karj vaparnyas bhag padale gele aanee kahee vela, manvi raktdravyacha srot mhanoon swatache rakt vaparnyas bhag padale gele. mulanmadhye niyojit hastakshepadarmyan ghetalelya shejarchya shalyachikitsakachya sanyoji uutincha vapar karoon, protocol karya karat asalyachi pushti tine akheris kelee. vibhajan peshinchya gunasutranna vikhuranyasathi aanee tyanna mojane sope karnyasathi tine 'hypotonic shock' paddhat vaparali aanee tyanantar jodaninantar slide koradi kelee.
yaa protocolcha vapar karoon, gottierla aadhalale qee samanya mulanchya peshinmadhye 46 gunasutra asatat. meey 1958 madhye, tine trisomic mulachya peshinmadhye atirikt gunasutra pahile, joou daun syndrome asalelya vyaktinmadhye gunasutra vikrutincha pahila purava hota.
nikalanchi ghoshana.
tyaveli, armond-truso rugnalayatil prayogshalanmadhye slideschee chhayachitre ghenyas saksham sukshmadarshak navhata. gautiyarne tichya slides see. aine. aar. ess. madheel sahkari sanshodhak jerom lejyoon yanchyakade sopavalya, jyanni yaa kamasathi adhik susajj asalelya dusarya prayogshalet chhayachitre kadhanyachi tayari darshavali. august 1958 madhye chhayachitranni daun syndromechya rugnanmadhye atirikt gunasutra olakhale. tathapi, lejyoonne slides parat kelya naheet, parantu tyaeivaji haah shodh tyacha swatacha asalyache sangitale.
janewari 1959 madhye, naveen prakaranancha abhyas karoon aanee ingrajidware ashach prakarche sanshodhan rokhanyasathi, trauso prayogshalene vidnyan akadamichya karyavahitil slideschya vishleshanache parinam legioonla pratham lekhak, gautier sekand (tiche aadnav chukiche lihile gele) aanee turpin shevatcha lekhak mhanoon prakashit kelelya pepardware jaheer kele.
turpin chamoone pahile sthanantar aanee pahile gunasutra hatvane olakhale, parinami prakashananvar gautier saha-swakshari kelee.
shodhache shrey.
april 1960 madhye yaa sthitila trisomy 21 asey naav denyat aale. 1970 pasoon lejyoon foundation yaa shodhala pramukhyane lejyoonche kaam mhanoon protsahan denyas suruvat kelee. 2009 madhye gautiyarne dawa keela qee, tine tantrikdrushtya suru kelelya aanee nirdeshit kelelya kamavar teey avalambun asale taree, yaa shodhachi jababdari swikaranaya turpin aanee lejyoon yanni teela eka bajula thewale hote. chalakine hatalale gelyachi jaaniv asalelya gautiyarne trisomy 21 sodoon dildayal vikarane prabhavit mulanchi kalji ghenyakade parat jaanyacha nirnay ghetala.
jerom lejyoon foundation thampane sangitale qee aktoobar 1958 madhye turpinne legioonla lihilelya patratoon asey disun yete qee lejyoonne, aanee gautiyarne navhe, 47 vya gunasutrachi olakh patavali. gautiyarne mukhya shodh lavala yacha konatahi purava nahee asey foundation mhanane aahe.
31 janewari 2014 roji, gautier bordomadhil manvi aanee vaidyakeey anuvanshashastravaril satvya dvivarshik congressmadhye shodhatil tichya bhoomikebaddal bolanar hotee aanee french federation auph human geneticsche bhavya paritoshik prapt karnar hotee. jerom lejyoon foundation yaa satrachya chitrikaranasathi dandadhikanyanna pathvanyasathi bordo tribunal dii grand instanskadoon adhikrutata prapt kelee. shevatchya kshani, dhvanimudranacha vapar kayadeshir karyavahit keela jaau shakato, jyacha bachav karane tyanna parvadanar nahee, yaa chintene congress aayojakanni tiche sadarikaran radd karnyacha nirnay ghetala aanee tyaeivaji teela ticha puraskar khajgiritya midala.
insermchya nitishastra samiteene julai 2014 madhye eka nond jaaree kelee aahe, jyat marthe gautiyarchya nirnayak bhoomikechi aathvan karoon dilee aahe aanee vaidnyanik prakashne aanee lekhakanchya yadisathi aantarrashtriy niyamanchi aathvan karoon denyasathi yaa prakaranachi ubharani kelee aahe. yaa nondit mhatale aahe qee, "shodh itihas haah vidnyanachya itihasashi ekroop nahee aanee dnyanachya pramanikaran prakriya khoop vegali rahate... raymond turpin aanee marthe gautier yanchya anivarya yogdanashivay trisomicha shodh ashakya jhaala asata, tyamule hii khedjanak baab aahe qee tyanchi nave yaa shodhashi paddhatshirpane, sanvadachya babatit, parantu vividh puraskar aanee pratishthanchya niyuktitatemadhye dekhil sambandhit navhati."
marthe gautier yanchi french leason auph onorchya adhikari padavar niyukti karnyat aalee hotee aanee 16 september 2014 roji tyanna sanmanit karnyat aale hote. marthe gautier yanni, yapurvi, "lejyoon foundationchya nirlajjatebaddal santapoon" sammati denyapurvi donada haah farak nakarla aahe.
15 november 2018 roji tyanna national aurder auph meritchya commander mhanoon badhati denyat aalee.
vaidyakeey karkird.
trisomichya shodhanantar gautiyarne turpincha chamoo sodala aanee swatahla hriday-balrogasathi samarpit karnyasathi sarvajanik aarogya sevetil padasathi arj keela. pradhyapak nauel yanni cremlin bichetre rugnalayat navyane suru kelelya sevet teela kamavar thewale hote. tyanantar, tee insarmmadhye sanshodhanat master bunley.