
amine auxidase (tambeyukt)

amine auxidase (tambeyukt) (aoc) (aanee; purvi) heey amine auxidase enzymesche eka kutumb aahe jyamadhye prathamik-amine auxidase aanee diamine auxidase donhi samavisht aahet; heey enzymes anek neurotransmitter, histamine aanee zenobiotic emines biogenic emineschya vistrut shreniche auxidation utprerit karatat. teey diasulphide-sambandhit homodymer mhanoon kaam karatat. teey prathamik amineche auxidation aldehydesmadhye utprerit karatat, tyanantar amonia aanee hydrogen peroxideche prakashan hote, jyasathi prati upghatak eka tambe aayan aanee cofactor mhanoon topaquinone aavashyak asateh
yaa enzymeche 3 thurr prathamik amine (rch2nh2), h2o aanee o2 aahet, tarr tyachi 3 utpadane rcho, nh3 aanee h2o2 aahet.
tambeyukt amine auxideses heey jivanu, burshi, vanaspati aanee pranyanmadhye aadhaltat. procariotsmadhye, enzyme vividh amine tharanna carbon aanee nitrogenche srot mhanoon vaparnyas saksham karate.
heey enzyme oxidoriductaseshy sambandhit aahe, visheshtah jeey sweekarak mhanoon auxigen asalelya datyanchya ch-nh2 gatavar karya karatat. yaa enzyme vargache paddhatshir naav amine aaheh auxigen oxidoriductase (deminating) (tambeyukt). heey enzyme 8 chayapachay marganmadhye sahbhagi hoteh euria chakr aanee amino gatanche chayapachay, glycine, serine aanee threonin chayapachay, hystidine chayapachay, tyrosine chayapachay, fenilalenin chayapachay, tryptophan chayapachay, beeta-allenine chayapachay aanee alkalide jaivasanshleshan II. tyat 2 sahghatak aaheth tambe aanee pii. kyu. kyu.
rachana.
ksh-kiran sphatikalekhanadvare tambyachya amine auxideschi trimiteey rachana nishchit kelee gelee.
tambyache amine auxideses heey 70-95 kdachya mashroomchya aakarache sammoji mhanoon aadhaltat, pratyek monomarmadhye tambyacha aayan aanee sahasanyojakpane bandhalela redox cofactor, topaquinone (tpq) asato. sanrakshit tyrosine avasheshanchya anuvadanantarchya badaladvare tii. pii. kyu. tayar hote. tambe aayan teen hystidine avashesh aanee vikrut chauras pyramidal bhoomitimadhye done panyachya renunshi samanvayit aahe aanee utpreran aanee tii. pii. kyu. jaivajananmadhye tyache duheri karya aahe. catalytic domain heey copper amine auxidesmadhye aadhalanaya 3-4 domenpaiki sarvat mothe aahe aanee tyat done patrakanmadhye 18 strandche beeta sandwich asate. sakriy jaaga purali jaate aanee tharala pravesh denyasathi sanrachanatmak badalachi aavashyakta asate.
aine2 aanee aine3 aine-terminal kshetranmadhye eka samaan sanrachanatmak putt aahe, jyacha gabha alfa-beeta (4) neey banalela aahe, jithe helics gundallelya anty-parallel beeta-sheetschya viruddha pack keela jaato. kahee copper amine auxideseschya aine-terminalvar, tasech seela wall hydrolage aanee aine-acetylmuramoil-ell-alanine amidisej sarkhya sambandhit prathinanmadhye eka atirikt kshetra aadhalate. yaa domenmadhye alfa heliksabhovati valalelee paach-stranded antiperelal beeta-sheet asate.
karya.
eukeriotsmadhye tyanchi karye vyapak shreneet asatat, jyat peshi bhed aanee vaadh, jakham barey karane, nirvishikaran aanee peshi sanket samavisht aahet; eka aoc enzyme (aoc 3) kahee sastan pranyanchya uutinmadhye raktavahinyansambandhi sanlagnata prathine (vap-1) mhanoon karya karate.