karbachol

carbachol, jyala carbamilcolin asehi mhanatat aanee itaranmadhye meostat yaa brand navane vikale jaate, heey eka colinomimatic aushadh aahe jeey acetylcholine receptorsna bandhate aanee sakriy karate. tyamule tyache vargikaran collinergic agonist mhanoon kele jaate. heey pramukhyane vividh netravishayak karanansathi vaparale jaate, jase qee kachbinduvar upchar karnyasathi kinwa netra shastrakriyedarmyan vaparasathi. heey samanyatah netra dravan mhanoon dile jaate (i.eae., dolhyanche themb).
jarr mothya pramanat atipramanat (audhyogik aanee jahaj apghatannantar houu shakate) sevan kele tarr carbachol sarinchya tulanet parinam nirman karate aanee mhanunach yuu. ess. chya kalam 302 madhye paribhashit kelyapramane americet too eka atyant dhokadayak padarth mhanoon vargikrut keela jaato.ess. aapatkalin niyojan aanee samudayacha jaanun ghenyacha adhikar kayada (42 yuu.ess.see. 11002), aanee jyaa suvidha mothya pramanat utpadan karatat, sathavatat kinwa vapartat tyadvare kathor ahwal aavashyaktanchya adheen aahe.
jaagtik aarogya sanghatanechya aavashyak aushadhanchya yadeet tyacha samavesh aahe.
rasayanshastra aanee aushadhashastra.
carbachol heey collin carbamet aanee sakaratmak charge kelele chaturthansh amonium sanyug aahe. teey jatharantra-aatadyanchya margat changlya prakare shoshale jaat nahee aanee rakt-menducha adthala paar karat nahee. heey sahasa samyik netra kinwa netrantargat injectiondware dile jaate. collinesteresdware karbacholche chayapachay sahajpane hott nahee, tyachi kriya 2 teey 5 minitanchi suru hote aanee tyachi kriya kalavadhi sthanik prashasanasah 4 teey 8 taas aanee netrandarmyanchya prashasanasathi 24 taas asato. carbachol heey sthanik prashasanadvare kharab prakare shoshale jaat asalyane, shoshanala chalana denyasathi benzalconium chloride misalale jaate.
carbachol heey eka parasympathomimatic aahe jeey muscarinic aanee nicotinic receptors yaa donhina uttejit karate. samyik netra aanee netrantriy prashasanat tyache pramukh parinam mhanje ardhasutran aanee jaleey vinodatil vadhiv pravah.
manjar aanee undaramadhye, carbachol heey pontin reticularchya nirmitimadhye sookshm injection dile jaate tevha dolhyanchya jalad halchalila (raim) prerit karnyachya kshamatesathi prasiddha aahe. postsyneptic muscarinic collinergic receptors (mackers) sakriy karoon carbachol hii raim zopesarkhi sthitee baher kadhate.
alikadil punaravalokan asey soochit karate qee carbachol haah aay. see. see. kriyakalapancha eka majboot pravartak aahe, joou calcium-sakriy chloride vahini, anoctamine 1 dware madhyasthi keela jaato.
sanshleshan.
carbacol 2-chloroethanolchya yuriyachya pratikriyepasun suru houn 2-chloroethyl-carbamet tayar karnyasathi 2-charan prakriyet tayar kele jaau shakate, jeey nantar trimethylamine pratikriyedvare chaturthansh kele jaate.
sanket.
karbacholcha vapar pramukhyane kachbinduchya upcharanmadhye keela jaato, parantu too netra shastrakriyedarmyanahi vaparla jaato. kachbindu asalelya lokansathi dolhyatil daab qamee karnyasathi carbachol idropscha vapar keela jaato. motibindu shastrakriyedarmyan kadhikadhi putalyanna sankuchit karnyasathi yacha vapar keela jaato.
prathamik open-angle glucoma asalelya lokanmadhye intraocular daab qamee karnyasathi samyik netra prashasana vaparale jaate. motibindu shastrakriyedarmyan lains pratyaropanantar myosis tayar karnyasathi intraocular prashasana vaparale jaate. mutrashayachya nishkriy sthitivar upchar karnyasathi mutrashay rikame honyas uttejan denyasathi dekhil karbacholcha vapar keela jaau shakato.
bahutek deshanmadhye carbachol keval prescriptiondware upalabdh aahe. united stateschya baher, heey maukhik (2 mii. gra.) tablet mhanoon mootra dharan karnyasathi dekhil soochit kele jaate.
matbhed.
damaa, coronary apurti, gastraudodenal alsar aanee asanyam asalelya rugnanmadhye karbacholcha vapar, tasech itar serve muscarinic receptor agonistcha vapar pratibandhit aahe. yaa aushadhachi parasympathomimatic kriya yaa vikaranchi lakshane vadhvel.
atipramanat.
pranaligat atipramanatil parinam heey kadachit majjatantu ghatakachya prabhavasarkhech asateel (teey donhi collinergic pranalivar karya karatat, collinergic sankraman vadhavtat), parantu tyachi vishaktata khoopach kamkuvat asate aanee atipramanat virodh karane sope asate. jevha dolhyanni dile jaate tevha asha parinamancha dhoka qamee asato, kaaran matra khoopach qamee asatat (samyik viruddha pranaligat prashasana pahaa).

