payas 3

eae3 sumo-prathine ligaj buy heey eka enzyme aahe jeey manavanmadhye buy janukadware encode kele jaate.
payas kutumb.
sastan pranyanchya payas kutumbat chaar sadasya asatatah payas 1, payas 2, payas 3 aanee payas 4. drosophilamadhye, diaps/zimp navache ekach payas homolog olakhale gele aahe. yeastmadhye, siz 1 aanee siz 2 hii done payas-sambandhit prathine olakhali gelee. payas kutumbat 60 peksha jaast prathine asatat, tyapaiki bahutek pratilekhan ghatak asatat jeey ektar sakaratmak kinwa nakaratmakpane anek yantranandvare niyantrit kele jaau shakatat.
shodh.
aay. aii. ess. prathine moolatah abhyasanmadhye olakhali gelee hotee jyacha uddesh janus kinness (jeeck)/steet signalling marg samajoon ghene haah hota. mulat, payas 3 visheshtah interleukin-6 (il-6) sakriy murine myeloblast emm 1 peshinmadhye phosphorylated statt 3 shhee sanvad sadhatana aadhalun aale. haah parasparkriya parasparkriya dna bandhan kshetrashi bandhalya bandhalya buy dware madhyasthi kelee jaate. tyamule, statt 3 transcriptional kriyakalap heey lakshyit janukanshi tyache bandhan sharirikaritya rokhalyamule pratibandhit kele jaate. tyanantar, payas 3 heey emm. aay. tii. eff., aine. eff. keey. bii., smad aanee istrogen receptor yasah itar pramukh pratilekhan ghatakanche niyamak prathine dekhil asalyache aadhalun aale.
karya.
payas 3 prathine sumo (lahan ubiquitinsarkhe sanshodhak)-eae 3 ligaj mhanoon dekhil karya karatat jeey sumo prathinachya sahsanyojak jodanila vishisht lakshya tharanshi utprerit karate. heey anek pratilekhan ghatkanshi thet bandhale jaate aanee ektar tyanchya kriyakalapanna avarodhit karate kinwa vadhavate. yaa janukache paryayipane vibhajit pratilekhan prakar olakhale gele aahet, parantu yapaiki kahee prakaranche purn lambiche swaroop nishchit kele gele nahee.
kshetra.
suff-aii/bii, asenus aanee payas (sapp) kshetra payas prathinanchya aine-terminalvar sthit aahe. utkrantinusar sanrakshit kelele heey kshetra yeastpasoon teey manvi prathinanmadhye aadhalate aanee scaffold attachment factor aii aanee bii sarkhya itar chromatin-binding prathinandware samayik kele jaate. sapp kshetra farshi-sanlagnata pradesh/matricks-sanlagnata pradeshanmadhye upasthit asalelya samruddha dii. aine. aii. anukramanna olakhoo aanee jodu shakate. heey ghatak varanvar januk januk aadhaltat aanee pratilekhan niyamanasathi eka adviteey anoo sookshm vatavaran pradan karnyasathi anoo matricks prathinanshi sanvad sadhatat. serve payas prathinanchya sapp domenmadhye ell. ex. ex. ell. signature motif asate. hii swakshari rachana anugrahak aanee tyanche saha-niyantrak yanchyatil parasparsanvadat madhyasthi karnyasathi darshavili gelee aahe. payas 3 aanee androgen receptorchya bandhanisathi dekhil heey aavashyak aahe. ell. ex. ex. ell. rachana hii aine. eff. keey. bii. pii. 65 upghatkasah parasparsanvadasathi aanee aine. eff. keey. bii. pratilekhan kriyakalapanchya pratibandhasathi kiman aavashyakta darshavate. heey purvi varnan kele gele hote qee ell. ex. ex. ell. rachana hii kendrakamadhye payas 3 tikavoon thevanyasathi dekhil jababdar aahe.
pro-ill-esna-ill-thra (pinit) rachana payas prathinanchya atyant sanrakshit kshetrache pratinidhitva karate, jee payas 3 chya anoo dharnamadhye sameel asalyache darshavile gele. pinit domenmadhye, payas 382-132 pradesh vegala keela gela aanee eka avarodhak domain mhanoon darshavila gela joou emm. aay. tii. eff. aanee statt 3 transcription ghatak yaa donhila bandhato aanee pratibandhit karato. ring-finger-sarkhe zink-binding domain (aar. ell. dii.) heey payas kutumbatil sarvat sanrakshit domenpaiki eka aahe aanee sumo-eae 3 legace mhanoon payas 3 kriyakalapansathi mahatvache asalyache darshavile gele aahe. aar. ell. dii. kshetra heey heey buy buy chya sakaratmak niyamanat dekhil sameel aahe.
parasparsanvad.
payas 3 yachyashi parasparsanvad darshavila gela aaheh

