iodine-123

iodine-123 (123i) heey iodeenche eka kiranotsargi samasthanik aahe, jeey anoo-aushadh pratimemadhe vaparale jaate, jyat ekal-photon utsarjan sanganit tomography (spect) kinwa spect/seaty parikshancha samavesh aahe. samasthanik ardh-jeevan 13.2230 taas aahe; electron capturedware tellurium-123 paryant kshay 159 keey. eae. vhee. chya pramukh urjesah gamma kiranotsarg utsarjit karato (haah pramukhyane imagingsathi vaparla jaanara gamma aahe). vaidyakeey anuprayoganmadhye, gamma gamma kiranotsarg shodhala jaato. samasthanik samanyatah iodide-123, ionic swaroop mhanoon vaparale jaate.
utpadan.
iodine-123 heey cyclotronmadhye capsulemadheel zenonchya proton vikiranadvare tayar hote. zenon-124 eka proton shoshun gheto aanee zenon-123 tayar karnyasathi tabadtob eka neutron aanee proton gamavato, kinwa caesium-123 tayar karnyasathi done neutron gamavato, jeey zenon-123 madhye kshay hote. donhi marganni tayar jhalela zenon-123 nantar iodine-123 madhye kshay hoto aanee refrigeration antargat vikiran capsulechya aateel bhintivar adakato, nantar halogen pramanahin pratikriyemadhye soodiyam hydroxides baher kadhala jaato, jyayoge zenonpasoon neutron irradiationdware tayar jhalyanantar iodine-125 chya sankalanapramanech (adhik tapashilansathi 125i vareel lekh pahaa).
iodine-123 samanyatah 0.00 meater soodiyam hydroxide dravanat, 99.8% samasthanik shuddhatevar, soodiyam iodide mhanoon puravale jaate.
80 takke samasthanikdrushtya samruddha tellurium-123 chya proton cyclotron bombsfotadware oka rij rashtriy prayogshalet vaidyakeey vaparasathi 123i dekhil tayar kele gele aahe.
kshay.
jawaljawal sthir asalelya nuclide tellurium-123 chee uttejit sthitee tayar karnyasathi tapshilvar kshay yantrana mhanje electron capture (eae. see.) (tyache ardhayushya itake lamb aahe qee teey serve vyavharik karanansathi sthir manale jaate). jaate) hii uttejit sthitee metastable nuclear isomer kshayamadhye nahee nahee kshayamadhye kshayamadhye tayar karnyasathi pureshi urja samavisht nasate), tarr tarr qamee-urja nuclear isomer aahe joou tabadtob nondavalelya urjevar gamma jaminivaril sthiteet sthiteet kshay hoto, kinwa (13 takke vel) antargat rupantaran electron utsarjan (127 kevy) dware kshay hoto, tyanantar agadi qamee urjevar utsarjit sarasari 11 augar electron (50-500 ev). nantarchi kshay vahini dekhil jaminichi sthitee sthitee utpann karate. visheshtah antargat rupantaran kshay vahinimule, 123i haah purnapane shuddha gamma-utsarjak nahee, jaree too kahivela vaidyakiyadrushtya eka asalyache manale jaate.
radioisotopmadhil augar electron eka abhyasat cellularche qamee nuksan karatat asey aadhalun aale aahe, joparyant radionuclide thet cellular dnmadhe rasayanikaritya samavisht kele jaat nahee, jeey sadhyachya radiopharmaceuticals babatit nahee jeey radioactive label nuclide mhanoon 123i vapartat. adhik bhedak gamma kiranotsarg aanee 127 keey. eae. vhee. antargat rupantaran electron kiranotsargamule honare nuksan, isotopechya tulanene qamee ardh-aayurmanamule, isotopechya prarambhik kshayamule qamee hote.
vaidyakeey anuprayog.
thyroid roganchya nidan abhyasasathi iodeenche sarvat yogya samasthanik mhanje 123i. 24 tasanchya iodine grahan chachanisathi andaje 13.2 tasanche ardhayushya aadarsh aahe aanee thyroid ootee aanee thyroid karkarogachya metastasische nidan karnyasathi 123i chey itar fayade aahet. photonchi urja, 159 keey. eae. vhee., sadhyachya gamma gamma naee (soodiyam iodide) chrystal detectorsathi aanee pinhole collimatorsathi dekhil aadarsh aahe. tyat 131i peksha khoop jaast photon pravah aahe. tyach prashasit matresathi heey 131i chya mojanichya darachya andaje 20 putt dete, tarr thyroidver kiranotsargacha bhaar 131i chya tulanet khoopach qamee (1 takke) asato. shivay, yaa samasthanikavar kiranotsargacha bhaar qamee asalyamule, thyroid avashesh kinwa metastasisla 123i neey scan kelyane uutinche (grahan qamee jhalyamule) 'aashcharyakarak' hott nahee. tyach karananmule, 123i haah thyroid karkarogasathi kinwa kabari rogachya "upcharansathi" kadhihi vaparla jaat nahee aanee hii bhoomika 131i sathee rakheev aahe.
123i haah soodiyam iodide (naee) mhanoon puravala jaato, kahivela moolbhut dravanat jyamadhye too mukt ghatak mhanoon virghalala jaato. heey rugnala capsulechya swarupat, antahshira injectiondware kinwa (galatimadhye samavisht asalelya samasyanmule qamee samanyatah) peyamadhye sevan karoon dile jaate. iodine thyroid granthidvare ghetale jaate aanee nidanasathi thyroidchya karyatmak pratima midvinyasathi gamma camera vaparla jaato. hyperthyroidism aanee hypothyroidism nidanasathi iodeenche sevan (shoshan) mojanyasathi thyroidche parimanatmak mojmap kele jaau shakate.
matra badaloo shakate; thyroid imagingsathi aanee sampoorn sharirasathi shifaras kelee jaate, tarr grahan chachanicha vapar keela jaau shakato. eka abhyas aahe joou soochit karato qee dilelya matremule, tayaritil ashuddhatemule, anyatha jaast matrecha parinam prabhavipane houu shakato. radioiodine 123i chaa doses samanyatah asha vyaktindvare sahan keela jaato jeey sthir iodeenche mothe praman asalelya see. tii. scan, intravenous pylogram (aay. vhee. pii.) aanee tatsam imaging nidan prakriyemadhye vaparlya jaanarya vipareet madhyamanna sahan karoo shakat naheet. iodine heey allergykarak nahee.
itar imaging radiopharmaceuticals ii. madhye label mhanoon dekhil 123i vaparale jaate.jee.metayodobenzylguanidine (emm. aay. bii. jee.) aanee ioflupen.
khabardari.
radioiodine pradushan kadhoon takane katheen asoo shakate aanee kiranotsargi iodine kadhanyasathi visheshtah tayar kelelya nirjantukikaranacha vapar karnyacha sallah deela jaato. sansthatmak vaparasathi tayar keleli done samanya utpadane mhanje 'bind-iit' aanee 'aay-bind'. samanya hetuchi kiranotsargi nirjantukikaran utpadane aayodinsathi anekada nirupayogi asatat, kaaran tee keval tyacha prasar kinwa bashpibhavan karoo shakatat.

