tii. dii. dii. emm. 1

transmembrane epididimal prathine 1 hii eka transmembrane prathine aahe jee tdm 1 janukadware encode keleli aahe. pratibandhamule laa samanyatah samanyatah mhanoonahi olakhale jaate aanee tyat sahaa alfa-helics transmembrane pradesh asalele 273 amino acid encode kele jaatat. prathinanmadhye adnyat karya karnare 118 amino acid lambiche kutumb asate. tii. dii. dii. emm. 1 chey achook karya samajale nasale taree, too plazma membraincha avibhajya ghatak asalyacha andaj vartavala jaato.
januk.
locus.
tii. eae. dii. dii. emm. 1 haah gunasutre 1 varr sthit aahe, jeey vaja tokavar 1q25.3 varr aadhalate. pratibandhamule heey ekach exonne banalele aahe. aahe janukanchya parisarat glutamate-amonia legace (glool), lamb aantarjanukiy prathine nasalele coding rna 272 272 aanee sharp-empra niyamak kshetra 13543 13543 yancha samavesh aahe.
abhivyakti.
bahutek pramukh uutinmadhye tii. eae. dii. dii. emm. 1 vyakt keela jaato. januk vrushanat uchch staravar aanee hrudayat qamee patalivar tii. eae. dii. dii. emm. 1 abhivyakti asalelya itar serve uutinchya tulanet vyakt kele jaate. mendumadhye, pratibandhamule heey amigdala, hippocampus aanee stiritamadhye vyakt kele jaate. undaranchya mendut, aar. aine. aii. probecha vapar karoon samanya abhivyaktisaha tii. eae. dii. dii. emm. 1 shodhala gela. 
peshimadhye, aadhalanaya pramukhyane plazma patalat vyakt keela jaato. puttle-baddh asalelya itar prathinanpramanech, tii. eae. dii. dii. emm. 1 prathinanmadhye sanket peptidecha prakar adnyat asala taree, andajit sanket peptide asato. kaaran aadhalanaya itar transmembrane prathinansah anek vaishishtye samayik karate, heey soochit karate qee signal transduction aanee prathinanchi taskari yasarkhya vividh peshi prakriyanmadhye prathinanchi bhoomika asoo shakate.
januk pataliche niyaman.
pratibandhamule chaa abhivyakti namuna sarvavyapi hota. manavanmadhye tii. eae. dii. dii. emm. 1 emm. aar. aine. aii. chee vipulata madhyam teey qamee hotee.
prathine.
pratibandhamule prathinanche aanvik vajan andaje 31.3 kiloda aahe aanee pratibandhamule chey saiddhantik samvidhyut bindu (paee) 8.02 aahe. visheshtah, heey itar prathinanchya sarasari paipeksha vegale aahe kaaran tyanche paee 4-7 chya ph shreneet asate. heey soochit karate qee pratibandhamule prathinanmadhye bahutek prathinanchya tulanet moolbhut amino acidchi atiriktata asate. 
kshetra.
tii. eae. dii. dii. emm. 1 chey adnyat karyache ekach pramukh kshetra aahe jyache naav aahe qee. heey kshetra prathinanchya amino aesidchya 95 teey 219 vya sthanaparyant pasarlele aahe. qee madhye bahutek lucine zipper asate jeey samanyatah prathinanchya dimerisationshi sambandhit asate. qee madhye prathinanmadhil sahaa transmembrane pradeshanpaiki teen dekhil asatat aanee tyat uchch sanvardhanache amino acid vibhag asatat, jeey soochit karatat qee qee bahudha aadhalanaya prathin karyat mahattvachi bhoomika bajavate.
anuvadatmak badal poost qaraa.
tii. eae. dii. dii. emm. 1 heey anek anuvadanantarchya badalanchya adheen aahe. andajit phosphorylation athara thikane aahet. itar vishisht sthalanmadhye aine-glycosylation site, kesin keynage II phosphorylation site, lucine zipper pattern, done aine-myristylation sites aanee teen protein keynage see phosphorylation sites yancha samavesh hoto. aine-glycosylation heey puttle prathinanche aanakhi eka vaishishtyapurn vaishishtya aahe aanee teey srav aanee cytoskeletal sanghatanet sameel aahe. kesin kinez II haah prathinanchi sthirata aanee peshi sanket pratisadat guntalela aahe. lucine zippers heey anukram rachana aahet jeey prathine-prathine parasparsanvad sulabh karatat. aine-myristillation sites legand binding aanee prathinanchya gatishilatemadhye guntaleli aahet. prathine kinage see phosphorylation sambandh peshi prasar aanee januk abhivyaktichya niyantranashi aahe.
rachana.
tii. dii. dii. emm. 1 chee duyyam rachana aine-terminswar mukt yadruchchik coil aanee ekach alfa helixs suru hote. pratibandhamule madheel sahaa transmembrane prathine sanrachanatmakdrushtya samaan alfa helices mhanoon darshavili jaatat. prathinancha haah bhag aine-terminuschya tulanet agadi ghanroop aahe. alfa helisesmadhye samanyatah pramukhyane hydrophobic avashesh asatat, jeey plazma patalamadhye asalelya yaa pradeshanshi sanrekhit hotat. alfa helics dekhil samanyatah dii. aine. aii. bandhan rachneshi sambandhit asatat.
samarupata/utkranti.
paralog.
tii. eae. dii. dii. emm. 1 madhye tii. emm. eae. emm. 45aii. aanee tii. emm. eae. emm. emm. asey done dnyat paralog aahet. 
orthologs.
manvi januk tii. eae. dii. dii. emm. 1 sathee 100 hoon adhik ortholog astitvat aahet. yapaiki dnyat ortholog heey keval sastan prani, ubhaychar aanee mashanmadhye astitvat asalyache aadhalale.aadhalalelya serve orthologschya vichalanachya tarkhechi tulana 'homo' sapiens 'shhee kelee gelee."phisha pratibandhamule heey manvi manvi sarvat durvar sambandhit ortholog aahet, jyat vichalanachi sarvat durchi sarasari tarikh 46.4 kotee varshanpurvichi aahe. tddm 1 sathee ortholog haah hadanchya mashanmadhye astitvat asatana, "protopterus annectains" madheel tyachya astitvacha purava mhanoon, janukache ortholog cartilaginus mashanmadhye barechada aadhalale. 
utkranti.
pratibandhamule chya aanvik utkranticha sapeksh darr haah fibrinogen alfachya tulanet agadi samaan hota aanee cytochrome seechya utkranti darapeksha khoopach vegwan hota.
parasparsanvadi prathine.
stringdware stringdware aadhalanaya prathinansathi anumanit karyatmak bhagidar.
vaidyakeey mahatva.
mageel karkarog sanshodhan abhyasannusar, januk-aadharit sahyog vishleshanat asey aadhalun aale aahe qee tii. dii. dii. emm. 1 aanee glool hii done januke yakrut karkarogacha sarvat samanya prakar asalelya hipatities bii vishanushi sambandhit hepatocellular carcinomashi sarvat lakshaniyaritya parasparsambandhit aahet. keratinocyteshi tyacha sambandh aanee bhrun pratyaropan aanee vikasache mahattvache niyamak asalelya asalelya pratibandhamule pratibandhamule laa lakshaniy vaidyakeey mahatva dekhil aahe.

