
tii. aar. pii. emm. 1

kshanik receptor sambhavya cashion channell upkutumb emm. sadasya 1 heey eka prathine aahe jeey manavanmadhye "tii. aar. pii. emm. 1" janukadware encode kele jaate.
karya.
yaa janukadware encode kelele prathine heey gair-nivadak cashion vahinyanchya kshanik receptor potential (tii. aar. pii.) kutumbache sadasya aahet. heey drushtipatalat, dvidhruvi peshinvar sambodhalya jaananya dvidhruvi peshinchya upasanchat vyakt kele jaate. yaa peshi ektar rodd kinwa shankunsah synaps tayar karatat, tyanchyakadun sanket gola karatat. andharat, signal neurotransmitter glutametchya swarupat yeto, joou jee protein-coupled receptor (jee. pii. see. aar.) signal transduction cascadedware shodhala jaato. jee. pii. see. aar. chayapachay glutamate receptor 6 dware glutamatecha shodh ghetalyane tii. aar. pii. emm. 1 vahini bund hote. prakashachya prarambhi, glutamateche prakashan thambavale jaate aanee emm. gloor 6 nishkriy kele jaate; yacha parinam tii. aar. pii. emm. 1 vahini ughadane, soodiyam aanee calciumcha pravah aanee dvidhruvi peshiche vidhruvikaran hote. 
drushtipatalavyatirikt, tii. aar. pii. emm. 1 heey melanocytesmadhye dekhil vyakt kele jaate, jeey tvachetil melanine-utpadak peshi aahet. tii. aar. pii. emm. 1 chee abhivyakti melanoma aakramakatela ulatya prakare parasparsambandhit aahe, jeey soochit karate qee teey melanoma metastasis dadapun takoo shakate. tathapi, tyanantarchya sanshodhanat asey disun aale qee, swatah tii. aar. pii. emm. 1 prathinanaivaji, 'tii. aar. pii. emm. 1' janukanchya antargrahamadhye asalela microrna haah arbud dabna karyasathi jababdar asato. tii. aar. pii. emm. 1 aanee microrna yaa donhichi abhivyakti microfthalmia-sambandhit pratilekhan ghatkadvare niyantrit kelee jaate.
vaidyakeey mahatva.
tii. aar. pii. emm. 1 madheel utparivartan heey manavanmadhil janmajat sthir andhatva aanee appalusa ghodyanmadhil coat spott karnyachya namunyanshi sambandhit aahet.