ductus arterios

ductus arterios, jyala ductus botali dekhil mhanatat, jyala italian sharirshastradnya leonardo botalo yanche naav denyat aale aahe, hii vikasit hott asalelya garbhatil eka raktavahini aahe jee fuffusiy dhamanichya thadala nikatvarti avarohi mahadhmanishi jodate. heey ujavya nilayatil bahutek raktala garbhachya dravane bharalelya kaam naan naan fuffusanna bajula saroo dete. janmachya velee bund jhalyavar, teey ligamentum arteriosam banate.
vikas aanee rachana.
garbh vikasadarmyan davya 6 vya mahadhamani kamanitoon ductus arterios tayar hote aanee mahadhamani kamanichya antim bhagala (mahadhamanicha asthama) aanee fuffusiy dhamanichya pahilya bhagala jodale jaate.
vikarah paytant ductus arterios.
parinam.
janmanantar ductus arteriosus bund naan jhalyane paytant ductus arteriosus navachi sthitee udbhavate, jyamule mahadhmanitun fuffusiy dhamanimadhye raktacha asamanya pravah hotoh eka davikadoon ujavikade jaanara shunt. jarr durust naan kelyas, yamule sahasa fuffusiy uchch raktadab hoto, tyanantar ujavya nilayatil hrudayavikaracha tras hoto, tasech sambhavya hriday sandhivat hoto.
prostaglandinschi bhoomika.
prostaglandinschi "eae" malika hii garbhachya sampoorn kalavadhit ductus arteriosasachi (raktavahinyanchya gulgulit snayunchya vistaradvare) mokalepana rakhanyasathi jababdar asate. naal aanee swatah daa yaa dohondware utpadit prostaglandin eae2 (pii. jee. eae. 2) haah eae. prostaglandinspacky sarvat shaktishali aahe, parantu prostaglandin eae1 (pii. jee. eae. 1) chee dekhil "daa" ughada thevanyat bhoomika aahe. pii. jee. eae. 1 aanee pii. jee. eae. 2 heey vishisht pii. jee. eae.-sanvedanshil receptorschya (jase qee eae. pii. 4 aanee eae. pii. 2) sahbhagadvare ductus arteriosasla ughade thevatat. eae. pii. 4 haah daa. chya pii. jee. eae. 2-prerit vistarashi sambandhit pramukh receptor aahe aanee gulgulit snayu peshinmadhye daa. chya palikade aadhalu shakato. 
janmanantar lagechach, pii. jee. eae. 2 aanee eae. pii. 4. yaa donhi receptorschi patali lakshaniyaritya qamee hote, jyamule daa bund houu shakate aanee prasutinantarche samanya parisancharan prasthapit houu shakate.
naun-steroidal anty-inflammatory aushadhanchi bhoomika.
prostaglandinche utpadan rokhanari nonsteroidal anty-inflammatory aushadhe (aine. ess. aii. aay. dii. ess.) deuun ductus arterios bund honyas pravrutt kele jaau shakate. sarvat samanya aine. ess. aii. dii. mhanje indomethacin, jeey sahasa janmanantarchya pahilya aathvadyat dile jaate. tathapi, fuffusanchya perfusions janmajat dosh asalelya upasthitit (udaa.jee. fuffusiy stenosis aanee ductsmadhun davikadoon ujavikade shunt), prostaglandin upcharasah ductus ughada thevun pranvayukaran sudharane yogya tharoo shakate. tathapi, asamanya ductsmadhye asey upchar aprabhavi asatat. ductuschi satatyata itar vikrutinshi sambandhit asoo shakate aanee mahilanmadhye adhik samanya aahe. pii. jee. eae. 2 nirmiti rokhoon, eae. pii. 4 receptor sakriyakaran qamee hoil aanee samanya parisancharan suru houu shakate. garbhadharanechya velee ushira ghetalelya aine. ess. aii. dii. mule naal olandu shakate aanee garbhatil daa akali bund houu shakate. yaa prakaranat, aine. ess. aii. dii. ess. chey parinam ulatavanyasathi aanee garbhadharanechya urvarit kalasathi daa. chee patency rakhanyasathi bahya pii. dii. eae. 2 dile jaau shakate.
ghatana.
paytant ductus arteriosus daun syndrome (dii. ess.) asalelya andaje 4 takke arbhakanvar parinam karato. bharbharatila naan yene heey yaa sthitiche eka atishay samanya lakshan aahe.
patency rakhane.
kahee prakarchya janmajat hriday doshanmadhye (udaa.jee.mothya dhamanyanche sankraman), prostaglandins heey daa ughade thevanyasathi dile jaau shakatat, jyamule shastrakriya hoiparyant raktache satat parisancharan aanee pranvayukaran houu shakate.
itar prani.
fuffusachya purvajanmadhil fuffusansah fuffusachya dhamnyanmadhil aanee prushthiy mahadhmanimadhil sambandh mhanoon ductus arteriosus vikasit jhaala. garbhachya vikasadarmyan, sarpatanare prani, pakshi aanee sastan prani yaa sarvanmadhye ektar eka kinwa done jodidar ductus arteriosi asatat, jeey fuffusanpasun door asalelya garbhachya raktala shunt pradan karatat.

