
aviptadil

eviptadil heey manvi vasoactive aatadyansambandhi peptideche (vhee. aay. pii.) eka injectionyogya krutrim sootra aahe. 
vhee. aay. pii. chaa shodh 1970 madhye lagla aanee tyacha vapar tivra shwasan vikar syndrome (aii. aar. dii.), damaa aanee dirghakalin avarodhak fuffusiy rog (see. oo. pii. dii.) yasarkhya vividh dahak paristhitinvar upchar karnyasathi keela jaato.
niyamak itihas.
covid-19 madheel aar. dii.
abhyasat asey aadhalun aale aahe qee covid-19 sambandhit ards asalelya gambhir aajari rugnansathi eviptadil fayadeshir tharoo shakate. active-3, eviptadil actate (zaisamy) chee chachani ghenari chachani, rugnanchi bharati karat aahe. aaradcha jaast dhoka asalelya rugnansathi shvasat ghetalelya eviptadilchi swatantra chachani suru aahe. tyach sanketasathi antahshira eviptadilchi chachani februwari 2021 madhye purn jhaali.
yuu. ess.-israyali neurox ink. neey united statesmadhye eviptadil vikasit karnyasathi releaf therapeuticshi bhagidari kelee. juuna 2020 madhye, yuu.ess. ann aanee aushadh prashasanane covid-19 madheel shwasan samasyechya upcharasathi eviptadilala jalad gatine padnam dile. september 2020 madhye, neuroxney atidakshata vibhagat asalelya rugnanmadhye tyachya vaparasathi yuu. ess. eff. dii. aii. laa aapatkalin vapar adhikrutatesathi vinanti sadar kelee.
janewari 2021: zuvents healthcare limitedne covid-19 upcharanmadhye aapatkalin vaparasathi bharatachya aushadh niyantrakakadun eviptadilsathi manjuri magitali. mumbaitil zuventus healthcare limited. eviptadil injectionyogya formulation tisya tappyatil clinical chachanya karnyas manyata midali aahe. sekne nondavale qee zuventsne samitisamor sudharit tappa 3 clinical chachani protocol sadar keela hota aanee "tapshilvar vicharvinimay" kelyanantar, tyane aushadhasah tappa 3 chachanyanna parvanagi denyachi shifaras kelee.
meey 2021: aine. aar. ex. pharmaceuticalsne zysamitum (eviptadil-actate) sathee sakaratmak parinam jaheer kele aanee shwasan bighadane grast asalelya rugnanmadhye gambhir covid-19 varr upchar karnyasathi yuu. ess. eff. dii. aii. kadey aapatkalin vapar adhikrutata arj sadar keela.
april 2022: kendriya parwana pradhikaran, dii. see. jee. aay. neey zuventus healthcare limitedla 'auxiptadil' yaa brand navane, gambhir covid-19 asalelya rugnanvar shastrane upchar karnyasathi, evipatadil utpadan aanee vipanan parvanagi dilee.
erectile disfunctionsathi eviptadil/fentolamine sanyojan (edd).
aktoobar 2000 yuu. keey. (invicorp): evidadil, adrenergic aushadh fentolaminechya sanyogane, erectile disfunction (edd) rugnansathi eka prabhavi paryayi upchar mhanoon manjur aahe. edchya upcharasathi eka matrechya intracavernosal injectionmadhye 25 microgram eviptadil aanee 2 migra fentolamine macillate asate. erectile disfunction upcharasathi vaparali jaanari eviptadil matra, kanyachya upcharanpeksha khoopach qamee asate.
vasoactive aatadyansambandhi peptide (vhee. aay. pii.).
vasoactive aatadyansambandhi peptide (vhee. aay. pii.) heey 28 avashesh asalele amino acid peptide aahe, jeey pahilyanda 1970 madhye vaishishtyikrut kele gele hote, jeey suruvatila porcin duodenumpasoon vegale kele gele hote. sravi/glucagan samprerak super familicha sadasya asalela vhee. aay. pii. haah suruvatila tyachya shaktishali vasodilatory prabhavanmule (tyachya navapramane) sapadala hota. vhee. aay. pii. madhyavarti aanee paridhiy majjasansthemadhye tasech pachan, shwasan, punarutpadak aanee hriday v raktavahinyasambandhi pranalinmadhye neurotransmitter aanee neuroendocrine mukt karnara ghatak mhanoon mothya pramanat pasarla aahe. heey parinam, majjatantu, upakala aanee antahsravi peshi karyanchya vikas, vaadh aanee niyantranasandarbhat sharirik aanee rogshastriy prakriyanchya vistrut shreneet yogdan detat.
vhee. aay. pii. receptors.
vhee. aay. pii. heey done receptorsver karya karate-vhee. pii. aii. see. 1 aanee vhee. pii. aii. see. 2, jeey jee-prathine-jodalele receptors (jee. pii. see. aar. ess.) chey buub varg aahet.vhee. pii. aii. see. 1 pramukhyane fuffus aanee tii-lymphocytesmadhye aadhalato, tarr vhee. pii. aii. see. 2 pramukhyane gulgulit snayu, mast peshi aanee fuffusachya shleshmalatechya mool bhaganmadhye disun yeto.
vhee. aay. pii. chee abhivyakti.
vhee. aay. pii. madhyavarti aanee paridhiy majjasansthanmadhil neuronsmadhye tayar hote. vhee. aay. pii. pramukhyane jee. aay. margatil myenteric aanee submucosal neurons aanee majjatantu terminalsmadhye sthanbaddh aahe. wii. aay. pii.-positive majjatantunchya kiman done loksankhyanmadhun, jase qee acetylcholine (aii. see.), aii. tii. pii., serotonin (5-etch. tii.), padarth pii. (ess. pii.), jee. ell. pii.-2, asha asankhya uttejanandware antarjalik vhee. aay. pii. sodalya jaatatah collinergic aanee naun-collinergic vhee. aay. pii.-sodananya majjatantu. giinii pigchya lahan aatadyanmadhye, shleshmal aanee sabmyukosamadhil bahutek vhee. aay. pii.-positive majjatantu heey naun-collinergic secretomotor neurons asatat aanee manvi bruhadantrakar snayunmadhye neuronal nitrick auxide synthes (aine. aine. oo. ess.) saha changlya prakare collocalise kelele asatat. vhee. aay. pii. rogpratikarak peshinmadhye dekhil vyakt keela jaato, jase qee sakriy tii peshi aanee mhanoon lasika uutinmadhil vhee. aay. pii.-airjik ineration vyatirikt, peeyarche patches, pleeha aanee lasika nodes lasika uutinmadhye upasthit asato. majjatantu strotachya bajula, hriday, thyroid, mootrapind aanee jee. aay. marg yaa antahsravi avayavanmadhun dekhil vhee. aay. pii. vyakt keela jaato aanee sodala jaato.
vasoactive aatadyansambandhi peptide (vhee. aay. pii.) aanee sars-cove-2.
vhee. aay. pii. fuffusanmadhye atyant sthanik aahe aanee vhee. pii. aii. see. 1 receptordware vayuvahak prakar II (2) peshinshi jodala jaato. fuffusiy upkalamatil keval 5 takke peshi aahet. angiotensin rupantarit karnare enzyme 2 (ess 2) prushthbhagavaril receptors II peshinmadhye asatat. 2 peshi prushthbhagavarche dravya tayar karatat aanee prakar 1 upakala peshinchya dekhbhalimadhye mahattvachi bhoomika bajavtat. sars-cove-2 tyachya spike prathinansah ess 2 prushthbhagachya receptorsna bandhun II peshinmadhye pravesh karato.