
ulotaront

ulotaront (; vikasatmak sanket september-363856, september-856) heey eka tapasatmak manovikari aahe jyachya schizophrenia aanee parkinson rogachya manovikarachya upcharasathi vaidyakeey chachanya suru aahet. cycogenics inkchya sahkaryane heey aushadh sapadale. aanee manojananshastrache vartan aanee aii. aay.-aadharit phenotypic aushadh shodh munch, smartcube vaparoon sannovian pharmaceuticals. ulotaront haah vaidyakeey vikasachya tisya tappyat aahe.
sanshodhanatun asey disun aale aahe qee eulotarontmule plesibopeksha panchya ekoon gunanmadhye baselinepasoon jaast ghat hote. placebochya tulanet, ulotaronts upchar dekhil zopechya gunavattetil sudharaneshi sambandhit hote. sadhyachya upcharanchya tulanet tyachya vadhiv parinamkarakta aanee mothya pramanat qamee jhalelya dushparinamanmule ulotarontla eka yashasvi upchar paddhatiche padd denyat aale.
pratikool parinam.
ulotarontcha pratikool parinam profile itar manovikarachya tulanet vegala aahe kaaran tyachya krutichya yantranemadhye mendutil dopamine receptorscha virodh samavisht nasato, joou tyaa ghatkansah udbhavu shakananya aushadh-prerit halchal vikaransathi (akathisiyasarkhya) jababdar asato. prathamik vaidyakeey chachanyanmadhye nondavalelya kahee pratikool ghatana mhanje nidranash, aswasthata, malmal, atisar aanee apasmruti.
aushadhashastra.
krutichi yantrana.
schizophrenia upcharanmadhye ulotarontchya krutichi yantrana aspasht aahe. tathapi, heey trace amine-sambandhit receptor 1 (taar 1) aanee serotonin 5-etch. tii. 1 aii. receptorsver eka agonist asalyache manale jaate. hii krutichi yantrana upalabdh manovikarachya aushadhanmadhye adviteey aahe, jee samanyatah dopamine receptorscha (visheshtah dopamine dii 2 receptor) virodh karatat.
pharmacokinetics.
ulotarontche achook pharmacokinetic profile nondavale gele nahee, jaree vikaskane suchavale aahe qee pharmacokinetic deta darroj ekada doses ghenyas samarthan deto.
sanshodhan.
2018 paryant, luracidone (latuda) navachya aanakhi eka manovikarachya aushadhache nirmate, sanovian, preclinical research company cycogenicschya bhagidarit ulotarontavar vaidyakeey chachanya ghet aahe. yuu.ess. ann aanee aushadh prashasanane ulotarontla breakthroo therapyche padd dile aahe. schizophreniavyatiric, parkinson rogashi sambandhit manovikarachya upcharansathi ulotarontcha dekhil abhyas keela jaat aahe.
kshullak.
jaree eka ralmitaront chachani parinamkaraktechya abhavamule thambavavi lagali asali taree, ulotaront aanee ralmitaront heey 1 agonaust aahet jeey chikitsalayin chachanyanmadhye pohochale aahet. ralmitaront' aanee 'ulotaront' hii nave pahili done akshare ekmekanshi jodalyamule 'raul' heey naav tayar hote. trace-amainashi sambandhit receptorschya sanshodhanat agraganyanpaiki eka mhanje raul genetdinov.