mastadenovirus

mastadenovirus haah 'adenoviridae' kutumbatil vishanuncha eka vansh aahe. manav aanee itar sastan prani naisargik yazman mhanoon kaam karatat. yaa vanshat 51 prajati aahet. yaa sampoorn vanshamadhye manvi sansargachi anek atishay samanya karane samavisht aahet, jee serve shwasan sansarganpaiki 2 teey 5 takke, tasech jatharantra aanee dolhyanchya sansargasathi jababdar asalyacha andaj aahe. lakshane sahasa saumya asatat.
vishisht ushnakatibandhanmadhye serotype 3,5 aanee 7: khalchya shvasanmargache sankraman, serotype 8,19 aanee 37: mahamari keratoconjectivitis, serotype 4 aanee 7: tivra shwasan rog, serotype 40 aanee 41: gastroenteritis, serotype 14: sambhavya pranghatak adenovirus sansarg houu shakatat.
canine mastadenovirus aii (purvi canine adenovirus-1, cadavy-1) kutryachya pillanmadhye mrutyu kinwa itar mansahari prajatinmadhye encephalitisla karanibhoot tharoo shakato.
vyutpatti.
mastadenovirus' heey naav greek shabd 'mastos' 'stun' (mhanunach 'sastan prani') aanee 'adenovirus' yaa shabdanvarun aale aahe, jyala manvi adenoidsche naav denyat aale aahe, jyapasoon vishanu pratham vegala karnyat aala hota.
vargikaran.
yaa vanshamadhye khaleel prajati aaheth
rachana.
mastadenovirus" madheel vishanu aachchhadit nasatat, icosahedral bhoomitisah aanee tii = 25 samamitisah asatat. vyas sumare 90 nm aahe. genome resheey aanee vibhagalele nasatat, sumare 35-36 keey. bii. lambiche asatat. 40 prathinansathi genome code.
jivanchakra.
vishanuchi pratikruti hii anoo aahe. yazman peshimadhye pravesh haah vishanujanya tantu yazman karchya sanlagnata receptorshee jodoon keela jaato. tyanantarchya kalat, integreen pravesh receptorschya yajmanasathi penton prathinanche bandhan, vishanuchya clathryn-madhyasth endocytosisdware aanee tantunche galatidvare yazman peshimadhye antargatkaranat madhyasthi karate. kahee serotype macropinocytosis dekhil vapartat asey disate. lytic prathin vi dware yazman endosomal padadyamadhye vyatyay aalyane cytosolmadhye vishanujanya capsid sodale jaate. vishanujanya janukanchya kendrakakade sukshmanalikanchi vahtook ajunahi mukhya prathine VII aanee pramukhyane hexon aanee prathine ix neey banalelya aanshik capsiddware sanrakshit aahe. aine. pii. see. varr docking aanee capsid vyatyay. coor prathine VII dware madhyasthi karoon yazman kendrakamadhye vishanujanya janukam aayat karane. yazman aar. aine. aii. pole II dware prarambhik janukanche (eae. janukanche) pratilekhanah hii prathine vishanuchya pratikrutisathi pesheey vatavaran anukool karatat aanee vividh vishanuvirodhi sanrakshanancha pratikar karatat. madhyavarti januke kendrakamadhil dii. aine. aii. strand visthapanadvare dii. aine. aii. genomechi pratikruti sakriy karatat. l 4-22 k aanee l 4-33 k chya abhivyaktimule lavkar teey ushira badal hoto. yazman aar. aine. aii. pole II dware usheera janukanche (ell. januke) pratilekhan, mukhytah sanrachanatmak prathinanche sanketan. vishanujanya vishanujanya prathinandware sadar kelele yazman anuvad bund. kendrakamadhye naveen viriyansachi assembly. peshichya lisisdware virion sodale jaatat. vishanujanya proteazhost receptorsdware virian paripakvata, jee clathryn-madhyasth endocytosismadhye madhyasthi karate. pratikruti dii. aine. aii. strand visthapan modelche anusaran karate. dii. aine. aii.-templated transcription, kahee paryayi splissing yantranesah transcription paddhat aahe. anuvad ribosomal shantingdware hoto. anubhattiche vighatan, viroporin aanee lisisdware vishanu yazman peshitoon baher padato.
manav, sastan prani aanee prushthavanshiy prani heey naisargik aashraydata mhanoon kaam karatat. prasaranache marg mull-maukhik aanee shwasanmarg aahet.

