manvi garbh vikas

manvi bhrun vikas kinwa manvi bhrunjanan mhanje manvi garbhacha vikas aanee nirmiti. vikasachya suruvatichya tappyat vikasit peshinchya vibhajanachya aanee garbhachya pesheey vibhedachya prakriyedvare heey vaishishtyapurn aahe. jaivik drushtya, manvi sharirachya vikasamadhye ekpeshiy zaigotpasun praudh manavasathi vaadh hote. jevha shukranu peshi yashasviritya andakoshat (andashay) pravesh karate aanee villin hote tevha garbhadhan hote. shukranu aanee andyache anuvanshik sahitya nantar ekatra yeuun eka peshi zaigot tayar hote aanee vikasacha ankuran tappa suru hoto.
manavanmadhil garbh vikas, vikasachya pahilya aath aathvadyancha samavesh karato; navvya aathvadyachya suruvatila garbhala garbh mhanatat.
aath aathvadyanmadhye 23 tappe asatat.
manvi bhrunshastra haah garbhadhananantarchya pahilya aath aathvadyandarmyanchya yaa vikasacha abhyas aahe. garbhadharanecha (garbhadharanecha) samanya kalavadhi sumare nauu mahine kinwa 40 aathvade asato.
ankuran tappa mhanje garbhashayachya garbhashayachya prarambhik vikasapasoon garbhashayat pratyaropan purn hoiparyantcha kaal. ankuran avasthela sumare 10 divas lagatat. yaa tappyadarmyan, zaigot vibhajit houu lagato, jyala cleavage mhanatat. tyanantar eka blastocyst tayar hoto aanee garbhashayat pratyaropan kele jaate. garbhjanan heey jatharjananchya pudhil tappyasah suru rahate, jevha garbhache teen jantu thurr hystogenesis navachya prakriyet tayar hotat aanee neurulation aanee organogenesischya prakriya pudhe yetat.
garbhachya tulanet, garbhamadhye adhik olakhanyayogya bahya vaishishtye aanee vikasit vikasit avayavancha adhik sampoorn sanch asato. bhrunjanan prakriyechya sampoorn prakriyet januk abhivyakti, peshinchi vaadh aanee peshitil farak yaat samanvit avkashiy aanee tatpurte badal samavisht asatat. itar prajatinmadhye, visheshtah cordetsmadhye jawaljawal eksarkhich prakriya ghadate.
ankuran avastha.
garbhadhan.
jevha shukranu yashasviritya andashayat pravesh karato aanee jananendriyandware vahoon nenyat nenyat anuvanshik samagriche done sanch ekatra misalatat, parinami zaigot (ekach dvigunit peshi) tayar hote, tevha garbhadhan hote. heey sahasa eka phelopian nalichya ampulamadhye hote. zaigotmadhye purush aanee stree donhi gametdware vahoon nenyat yenari sanyukt anuvanshik samagri asate jyamadhye andashayachya kendrakamadhun 23 gunasutra aanee shukranunchya kendrakamadhun 23 gunasutra asatat. mytotic vibhajanapurvi 46 gunasutranmadhye badal hotat jyamule done peshi asalelya garbhachi nirmiti hote.
yashasvi garbhadhan teen prakriyandvare saksham kele jaate, jeey prajati-vishishtata sunishchit karnyasathi niyantran mhanoon dekhil karya karatat. pahila mhanje chemotaxis joou shukranunchya andashayachya dishene halchal nirdeshit karato. dusare mhanje, shukranu aanee undy yanchyat chikatanyachi susangatata udbhavate. shukranu andashayala chikatalyanantar, acrosomal pratikriyechi tisari prakriya hote; shukranunchya dokyacha pudhcha bhag acrosomne jhakalela asato jyamadhye pachansheel enzymes asatat jyamule jona pellucida khandit hoto aanee tyacha pravesh houu shakato. shukranunchya praveshamule calcium sodale jaate jeey itar shukranunchya peshinmadhye pravesh karnyas adthala aanate. andashayat samantar pratikriya hote jyala jona pratikriya mhanatat. yamule cortical granulesche prakashan hote jeey shukranu receptor prathine prathine enzymes sodatat, asha prakare polyspermila pratibandh karatat. daane dekhil plazma patlasah misalatat aanee pudhil shukranuncha pravesh rokhanyasathi jona pelucidamadhye asha prakare badal karatat.
vichhedan.
jevha zaigot mitosisdware done peshinmadhye vibhagato tevha vichhedan prakriyechi suruvat chinhankit kelee jaate. haah mitosis suru rahato aanee pahilya done peshi chaar peshinmadhye, nantar aath peshinmadhye aanee ashach prakare vibhagalya jaatat. pratyek vibhagala 12 teey 24 taas lagatat. zaigot itar konatyahi peshinchya tulanet motha asato aanee aakarat konatihi ekoon vaadh naan karata too fatato. yacha arth assa qee pratyek salag upavibhagasaha, nabhikiy aanee peshidravyiy samagriche praman vadhate.
suruvatila, blastomeres (sproutsathi greek) navachya vibhajak peshi, bhinn nasatat aanee andashayachya jona pelucidamadhye vedhalelya golamadhye ektrit kelya jaatat. jevha aath blastomere tayar hotat, tevha teey sankuchit houu lagatat. teey antar jodani vikasit karoo lagatat, jyamule tyanna ekatmik paddhatine vikasit karata yete aanee sharirik sanket aanee paryavaraniy sanketanna tyanchya pratisadacha samanvay sadhata yeto.
jevha peshinchi sankhya solachya aaspas asate, tevha jona pelucidamadhil peshinchya ghan golyala maurula mhanatat.
sphot.
fatane haah blastulation pahila tappa aahe, blastocyst tayar karanyachi prakriya. peshi peshichya bahya tharamadhye, jyala trophoblast mhanatat, aanee aateel peshi vastumanat, bhinn hotat. pudhil aakunchananantar, vaiyaktik bahya blastomeres, trophoblasts, vegale karata yet naheet. teey ajunahi zoan pellucidamadhye bandist aahet. heey sankshepan sanrachanela jalrodhak banavanyasathi karya karate, jyamadhye peshi nantar sravit kartil assa drav asato. peshinche aateel vastuman vegale houn bhrunstambh banate aanee eka tokala dhruvikaran hote. teey ekatra bund hotat aanee antar jodani tayar karatat, jyamule cellular sampreshan sulabh hote. heey dhruvikaran blastocol navachi pokali sodate, jyamule eka rachana tayar hote jyala aata blastocyst mhanatat. (sastan pranyanvyatirikt itar pranyanmadhye yala blastula mhanatat). traufoblast blastocolmadhye drav sravit karatat. parinami blastocystchya aakarat vaadh jhalyamule too jona pelucidamadhun baher padato, jeey nantar vighatit hote. yaa prakriyela zona hatching mhanatat aanee tee garbhachya vikasachya sahavya divashi, pratyaropan prakriyechya tabadtob aadhi hote. manvi garbhachya udrekala blastocystchya peshindware sravalelya protijdware aadhar deela jaato, jeey jona pelucidachi prathine pachavatat aanee chhidra nirman karatat. mug, blastocystchya laybaddh vistar aanee aakunchanamule, blastocystchya aateel dabat vaadh hote, chhidra vistarte aanee shevati yaa kathor lifafyatoon blastocyst baher yeu shakato.
aateel peshi dravyaman purv-garbh, amniyan, pivali pishavi aanee alantoisla janm deil, tarr garbhanalcha garbh bhag bahya trophoblast tharatoon tayar hoil. garbh aanee tyachya patalanna sankalpana mhanatat aanee yaa tappyaparyant sankalpana garbhashayaparyant pohochali aahe. zona pellucida shevati purnapane nahishi hote aanee aata ughad jhalelya trophoblastchya peshi blastocystala endometriumshi jodanyas anumati detat, jithe teey pratyaropan karel.
bilaminar jantu diskche done mukhya thurr asalelya hypoblast aanee epiblastchi nirmiti aanee aathvadyachya suruvatila hote. bhrun aanee trophoblast donhi done up-staranmadhye rupantarit hotil. aateel peshi hypoblast tharat rupantarit hotil, jeey epiblast navachya aanee tharala vedhatil aanee heey thurr bhrun disk tayar kartil jee garbhat vikasit hoil. traufoblast done up-thurr dekhil vikasit karelah cytotrophoblast, jeey cincitiotrophoblastch samore aahe, jeey endometriummadhye aahe. pudhe, exocoilomic membrain kinwa huser membrain navacha aanakhi eka thurr disel aanee cytotrophoblast tasech adim jardalu pishavila vedhel. synceteotrophoblast vadhel aanee lacunar stage navachya tappyat pravesh karel, jyamadhye kahee riktika disatil aanee pudhil divasant raktane bharalya jaatil. pivalya pivalya pishavicha vikas hypoblastic sapat peshinpasoon suru hoto, jeey exocoilomic membrain tayar karatat, jeey cytotrophoblastchya aateel bhagala aachchadan karoon adim pivalya pivalya pishavi tayar karatat. synceteotrophoblastic peshindware matechya keshikanchya endothelial astarachi dhoop jhalyamule matechya cyanusoidschi nirmiti hote, jithun rakt aat pravesh karoo lagel aanee trophoblastic lacunamadhye aanee tyatoon vahoo lagel aanee garbhashay parisancharanas janm deil. tyanantar, pivalya pivalya pishavitoon pishavitoon naveen peshi trophoblast aanee exocoilomic patalamadhye sthapit kelya jaatil aanee atirikt-bhruniy mesodermla janm deteel, jyamule corionic pokali tayar hoil.
vikasachya aanee aathvadyachya shevati, trophoblastchya kahee peshi aat pravesh karatat aanee cincitiotrophoblastem golakar stambh tayar karatat. yaa stambhanna prathamik viilii mhanatat. tyach velee, itar sthalantarit peshi bahya-lobhi pokalimadhye duyyam kinwa nishchit jardaluchi pishavi navachi eka naveen pokali tayar karatat, jee adim jardaluchya pishavipeksha lahan asate.
pratyaropan.
andashayanantar, garbh swikaranyachya tayareet endometrial astarache strav astaramadhye rupantar hote. tyachya strav granthi lamb hott asalyane tee jaad hote aanee raktavahinya adhikadhik vadhatat. garbhashayachya pokaliche (kinwa garbh) heey astar aata decidua mhanoon olakhale jaate aanee teey tyachya vadhiv aantargranthiy uutinmadhye mothya sankhyene mothya decidual peshi tayar karate. blastocystemadhil blastomeres heey trophoblast navachya bahya tharat vyavasthit kele jaatat. trophoblast nantar aatalya tharamadhye, cytotrophoblastmadhy aanee baherchya tharamadhye, cincitiotrophoblastem vegale hote. cytotrophoblastmadhy cuboidal epithelial peshi asatat aanee peshi vibhajit karnyacha srot asato aanee synceteotrophoblast haah peshi simanvina eka syncitial thurr asato.
synceteotrophoblast, corionic vilichya andajadvare decidual epitheliummadhye blastocystche pratyaropan karate, jyamule nalcha garbh bhag tayar hoto. blastocyst lavlyanantar garbhanalika vikasit hote, jee garbhala garbhashayachya bhintishi jodate. yetheel deciduala decidua baselis mhanatat; too blastocyst aanee myometriumchya darmyan asato aanee nalcha matrubhag tayar karato. pratyaropanala hydrolytic enzymesdware madat kelee jaate jee epitheliumchi zeej karatat. synceteotrophoblast manvi corionic gonadotropin heey samprerak dekhil tayar karate, jeey corpus lutiummadhun progesterone sodanyas uttejan dete. progesterone raktavahinya aanee keshikanchya jaad astarane garbhashayala samruddha karate jenekarun teey vikasansheel garbhala oxygenyukt karoo shakel aanee tikavoon thevu shakel. garbhashayache poshan karnyasathi garbhashay tyachya peshinmadhun sathavalelya glycogenpasoon sakhar mukt karate. viilii shakha houu lagate aanee tyat garbhachya raktavahinya asatat. itar viilii, jyanna terminal kinwa free viilii mhanatat, teey poshak tatvanchi devanghevan karatat. garbhala naal jodanyasathi nabhichya dorat vikasit vikasit eka arund hote dandidware garbh trophoblastic kavchala jodala jaato.
deciduamadhil dhamanyanche punarnirmiti karoon, garbhanalatil antarvarniy jaganmadhye matechya raktacha pravah vadhavala jaato, jyamule vayuchi devanghevan hote aanee garbhat poshak tatvanche hastantaran hote. garbhatil kachara utpadane nalbhar pasartil.
jasjase synceteotrophoblast garbhashayachya bhintimadhye pravesh karoo lagate, tasatase aateel peshi dravyaman (bhrun) dekhil vikasit hote. aateel peshi dravyaman heey bhruniy moolpeshincha srot aahe, jeey pluripotent aahet aanee teen rogjantu thurr peshinpaiki konatyahi ekamadhye vikasit houu shakatat aanee jyat serve ootee aanee avyavanna janm denyachi kshamata aahe.
bhrun disk.
bhrunbhakshi eka bhrun disk tayar karate, jee done tharanchi bilaminar disk aahe, eka varcha thurr jyala epiblast (adim ectoderm) mhanatat aanee khalcha thurr jyala hypoblast (adim endoderm) mhanatat. amneotic pokali aanee pivalsar pishavi jeey hoil tyaa darmyan disk pasarleli asate. epiblast heey trophoblastchya shejari asate aanee stambhakar peshinpasoon tayar hote; hypoblast heey blastocyst pokalichya sarvat jawalche asate aanee cubidal peshinpasoon tayar hote. epiblast trophoblastpasoon khalchya dishene sthalantarit hote, jyamule amneotic pokali tayar hote, jyache astar epiblastpasoon vikasit jhalelya amnioblastapasun tayar hote. hypoblast khalee dhakalala jaato aanee pivalya pivalya pishaviche (exocolomic pokali) astar tayar hote. kahee hypoblast peshi blastocolchya aateel cytotrophoblast astaratoon sthalantarit hotat, jyamule vatet eka bahyakoshikiy matricks stravato. yaa hypoblast peshi aanee bahyakoshikiy matricksna husercha padada (kinwa exocoilomic padada) mhanatat aanee teey blastocolala zakoon jardaluchi pishavi (kinwa exocoilomic pokali) tayar karatat. hypoblastchya peshi yaa reticulumchya bahya kathanvar sthalantarit hotat aanee extraembronic mesoderm tayar karatat; yamule extraembronic reticulummadhye vyatyay yeto. lavkarach reticulummadhye pockets tayar hotat, jeey shevati ekatra yeuun corionic pokali (extra embroyonic koelom) tayar karatat.
jatharprashvas.
sthalantarit epiblastdware tayar jhalelya peshincha eka resheey sangrah, adim resha, disun yete aanee heey jatharatrapanachi suruvat darshavate, jee garbhadhananantar sataravya divashi (aathvada 3) hote. jatharprakriya hii prakriya done-tharanchya bhrunachi teen-staranchya garbhat punarrachana karate aanee garbhala tyachya vishisht dokyapasoon shepatiparyant aanee samorun mage dishene, adim reshedvare dete, jee dwaipakshik samamiti sthapit karate. majjatantunche aayojak asalelya adim reshesamor eka adim node (kinwa adim gaath) tayar hote. adim nodchya madhyabhagi eka adim khadda tayar hoto joou thet khalee asalelya notocordshee jodala jaato. amneotic pokalichya prushthbhagachya epiblastmadhun node tayar jhaala aahe aanee haah nodach majjasansthecha aadhar mhanoon kaam kaam majjasansthechi plate tayar karnyas pravrutt karato. majjatantuchi plate ectodermal uutinchya adim reshechya viruddha tayar hoil jee majjatantuchya platemadhye ghatt houn sapat hote. tyaa pradeshatil epiblast adim khaddyachya thikani reshet khalee sarakato jithe pravesh navachi prakriya hote, jyamule mesoderm tayar hoto. yaa praveshamule epiblastmadhil peshi epithelial-messenkimal sankramanamadhye adim dorat jaatat; epithelial peshi messenkimal stame peshi banatat, multipotent stromal peshi jyaa vividh prakarchya peshinmadhye farak karoo shakatat. hypoblastla margabaher dhakalale jaate aanee pudhe jaaun amniyan tayar hote. epiblast halat rahato aanee mesoderm haah dusra thurr tayar karato. epiblast aata garbhachya teen jantu tharanmadhye vegala jhaala aahe, jenekarun bilaminar disk aata trilaminar disk, gastrula aahe.
ectoderm, mesoderm aanee endoderm heey teen jantu thurr aahet aanee teey teen paraspar aachchhadit sapat disk mhanoon tayar hotat. yaa teen staranmadhunach sharirachya serve sanrachana aanee avyav somitogenesis, hystogenesis aanee organogenesis yaa prakriyandvare prapt hotil. garbhasth endoderm hypoblastmadhye sthalantarit vikasit epiblastic peshinchya aakramanadvare tayar hoto, tarr mesoderm epiblast aanee endoderm darmyan vikasit vikasit peshindware tayar hoto. sarvasadharanpane, serve jantuche thurr epiblastmadhun tayar hotil. ectodermcha varcha thurr tvachecha sarvat bahya thurr, madhyavarti aanee paridhiy majjasanstha, dolhe, aateel qaan aanee anek sanyoji ootee nirman karel. mesodermcha madhala thurr hriday aanee rakt parisancharan pranalichi suruvat tasech hadey, snayu aanee mutrapindanna janm deil. endoderm aateel thurr fuffuse, aatade, thyroid, swadupind aanee mutrashayachya vikasasathi prarambhik bindu mhanoon kaam karel.
praveshanantar, garbhachya eka bajula peshi jithe pravesh karatat tithe eka blastopore vikasit hoto aanee too aatadyacha pahila rachnatmak tappa, archenteron honyasathi khol hoto. serve deuterostomspramane, blastopore guddwar banate tarr aatade garbhachya aanee bajula bogade bandhate jithe mukh hote. karyarat pachak nalisah, jatharprakriya aata purn hote aanee majjatantuncha pudhcha tappa suru houu shakato.
neurulation.
jatharprajvalanantar, ectoderm upakala aanee majjatantu uutinna janm deto aanee jatharkoshala aata majjatantu mhanoon sambodhale jaate. ectodermpasoon jaad plate mhanoon tayar jhaleli neural plate rund hott rahate aanee tyache toke neural folds mhanoon varchya dishene dumdu lagate. neurulation mhanje hii dumadanyachi prakriya jyamadhye neural plateche neural tubemadhye rupantar hote aanee heey chauthya aathvadyat hote. teey eka uthal majjatantu khambasah dumadatat, jee majjatantuchya pattyamadhye vibhajak madhyavarti resha mhanoon tayar jhaali aahe. jevha teey majjatantunchya shikharavar ekatra yeteel aanee bund hotil tevha patanchi unchi vadhat jaeel tevha heey adhik khol hote. adim reshechya sarvat kapaliy bhagatoon sthalantarit vikasit peshi paraxial mesoderm tayar karatat, jeey somitomeres tayar kartil jeey somitogenesischya prakriyet somitomeresmadhye vegale hotil jeey sclerotoms, syndtomes, myotomes aanee dermatomes tayar kartil aanee upasthi aanee haad, snayu, tvacha aanee snayu tayar kartil. madhyavarti mesoderm mutrajananashay margala janm deto aanee tyat peshi asatat jyaa adim reshechya madhya bhagatoon sthalantarit hotat. itar peshi adim reshechya coddle bhagatoon sthalantarit hotat aanee bajukadil mesoderm tayar karatat aanee sarvat coddle bhagadvare sthalantarit vikasit peshi extraembrionic mesodermmadhye yogdan detat.
bhrun disk sapat aanee goal suru hote, parantu akheris rund cephalic bhag aanee arund aakarachya kadalchya tokaparyant lamb hote. suruvatila, adim resha cephalic dishene vistarte aanee garbhadhananantar 18 divasanni tee nahishi hoiparyant parat yete. cephalic bhagat, rogjantucha thurr chauthya aathvadyachya suruvatila vishisht farak darshavito, tarr coddle bhagat too chauthya aathvadyachya shevati hoto. kapal aanee kadal neuropores haloohaloo lahan hotat, joparyant teey purnapane bund hott naheet (26 vya divasaparyant) aanee neural tube tayar karatat.
avyav aanee avyav pranalincha vikas.
organogenesis mhanje avayavancha vikas joou dolhe teey aathvya aathvadyat suru hoto aanee janmaparyant suru rahato. fuffusanpramanech kadhikadhi janmanantarhi purn vikas suru rahato. sharirachya anek avyav pranalinchya vikasat vividh avyav bhag ghetat.
rakt.
serve raktpesheenna janm janm raktapeshijanya moolpeshi mesodermmadhun vikasit hotat. rakt peshinchya samoohanmadhye, jyanna rakt bete mhanatat, rakt nirmiticha vikas pivalya pishavit hoto. rakt bete garbhachya baher, nabhichya putanvar, elantois, jodanara danda aanee corian, mesodermal hemangioblastspasoon vikasit hotat.
rakt betachya madhyabhagi, raktavahinyanmadhil raktavahinya hematopoetic mool peshi tayar karatat jyaa serve prakarchya rakt peshinche purvavarti aahet. rakt betachya parighamadhye raktavahinyanche purvavarti, raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavahinyanmadhil raktavah
hriday aanee rakt parisancharan pranali.
hriday haah vikasit honara pahila karyatmak avyav aahe aanee sumare 22 divasanni too raktala dhaddhadayla aanee pump karayala suruvat karato. majjatantuchya platechya pratyek bajula asalelya splanknopluric messenkimemadhil cardiac myoblasts aanee raktatil bete, cardiogenic pradeshala janm detat.heey garbhachya dokyajaval ghodyachya nalyachya aakarache kshetra aahe. 19 vya divasaparyant, peshi sanketanantar, yaa pradeshat nalya mhanoon done dhage tayar houu lagatat, kaaran tyanchyat eka lumen vikasit hoto. yaa done endocardial tube vadhatat aanee 21 vya divasaparyant ekmekankade sthalantarit hotat aanee eka adim hriday nalika, tubeler haart tayar karnyasathi ekatra yetat. heey garbhachya dumadanyane saksham hote jeey nalikanna vaksh pokalit dhakalate.
endocardial tube tayar hott asatana, vasculogenesis (parisancharan pranalicha vikas) suru jhaala aahe. heey 18 vya divashi splanknopluric mesodermmadhil peshinni angioblastmadhye farak karoon suru hote jeey sapat endothelial peshinmadhye vikasit hotat. heey ekatra yeuun angiocyst navachya lahan putke tayar karatat, jeey ekatra yeuun angioblastic dorr navachya lamb vahinya tayar karatat. raktavahinyanchya jaalyachya nirmitimadhye yaa dorkhand jaalikechya vyapak jaalyat vikasit hotat. angiogenesischya prakriyet naveen vahinyanchya atirikt ugavan aanee ankuranamule heey jaale vadhate. vasculogenesis aanee prarambhik vasculature vikasanantar, raktavahinyanchya punarnirmiticha eka tappa hoto.
nalika hriday vegane paach bhinn pradesh tayar karate. dokyapasoon shepatiparyant, heey infundibulum, bulbus cordis, adim nilay, adim alind aanee sinus venosus aahet. suruvatila, serve shiranmadhil rakt cyanus venosasmadhye vahate aanee shepatipasoon dokyaparyant trunks aarteriosasparyant jaate. heey mahadhamani aanee fuffusiy dhamani tayar karnyasathi vibhajit hoil; bulbus cordis ujavya (adim) nilayat vikasit hoil; adim nilay davya nilayat tayar hoil; adim karn davya aanee ujavya karnak aanee tyanchya upanganche pudhil bhag banel aanee sinus venosus ujavya karnak, cinotrial node aanee coronary sinuschya mageel bhagat vikasit hoil.
hridayala aakar denari hridayala aakar denari eka prakriya mhanoon hridayala aakar denyas suruvat hote aanee heey chauthya aathvadyachya akheris purn hote. hote prushthbhagavar kramadeshit peshi mrutyu (apoptosis) sanlayan honyas saksham karato.
chauthya aathvadyachya madhyat, cyanus venosusla teen pramukh shiranmadhun rakt milateh vitelin, nabhi aanee samanya cardinal vence.
vikasachya pahilya done mahinyant, aantar-aantrik chhidra tayar honyas suruvat hote. haah septum adim alindala ujavya aanee davya alindat vibhajit karato. pratham, too ardhchandrakar uutincha tukada mhanoon suru hoto joou septum primum mhanoon khalchya dishene vadhato. ardhchandrakar aakaramule austiyam primum mhanoon olakhalya olakhalya mukhadware rakt ujavya bajula davya alindakade halavanyas parvanagi denara alind purnapane bund honyas pratibandh hoto. heey pranalichya pudhil vikasasah bund hote parantu teey honyapurvi, varchya alindat dusare chhidra (ostiyam secondum) tayar honyas suruvat hote jyamule rakt satat qamee hott rahate.
dusra septum (septum secondum) septum primumchya ujavikade tayar houu lagato. yamule eka lahan ughadane dekhil rahate, foramen ovel jeey ostiyam secondumchya mageel ughadanyashi satat asate. septum primum eka chhotya pattyamadhye qamee keela jaato joou foramen ovelcha zadap mhanoon kaam karato aanee heey janmachya velee bund hoiparyant rahate. nilayanchya darmyan septum inferious dekhil tayar hoto joou snayuyukt interventricular septammadhye vikasit hoto.
pachan pranali.
dolhe aathvadyapasun pachan pranali vikasit houu lagate aanee baravya aathvadyaparyant, avyav yogyaritya sthit hotat.
shwasan pranali.
fuffusachya kalitoon shwasan pranali vikasit hote, jee vikasachya sumare chaar aathvadyannantar agragatchya nilay bhintimadhye disate. fuffusanchi kalee shwasanalikela aanee done parshvik vadhinna bronchial kalee mhanoon olakhate, jee pachvya aathvadyachya suruvatila vadhoon davya aanee ujavya mukhya shwasanalikela tayar karatat. yaa shwasanimule duyyam (lobar) shwasani tayar hotat; ujavikade teen aanee davikade done (fuffusachya bhaganchi sankhya pratibimbit karatat). duyyam shvasanipasun trutiyak shwasani tayar hote.
swarayantratil antargat astar fuffusachya kalitoon udbhavate, tarr tyache upasthi aanee snayu chauthya aanee sahavya swarayantra kamanitoon udbhavtat.
mootra pranali.
mootrapind.
vikasansheel garbhamadhye teen bhinn mootrapind pranali tayar hotatah pronephros, mesonephros aanee metanephros. keval metanephros kayamswarupi mutrapindamadhye vikasit hotat. heey tinhi madhyavarti mesodermpasoon tayar jhaale aahet.
pronephros.
cervical pradeshatil madhyavarti mesodermmadhun pronephros tayar hotat. teey karyasheel nasate aanee chauthya aathvadyachya samaptipurvi ksheen hote.
mesonephros.
mesonephros heey varchya vakshasthalachya teey varchya katibhagachya vibhaganmadhil madhyavarti mesodermpasoon tayar hote. utsarjak nalya tayar hotat aanee mesonephric vahinimadhye pravesh karatat, jee klokamadhye sampate. mahilanmadhye mesonephric duct atrophies, parantu purushanmadhye prajnan pranalichya vikasat sahbhagi hotat.
metanephros.
metanephros vikasachya pachvya aathvadyat disun yeto. mutramargatil kall, yaa mesonephric vahinichi vaadh, metanephric uutinmadhye pravesh karoon adim mootrapind shroni, mootrapind callis aanee mootrapind pyramid tayar karate. mutramargahi tayar hoto.
mutrashay aanee mutramarg.
vikasachya chauthya aanee satvya aathvadyandarmyan, mutramargatil chhidra heey klokala mutrajanan sinus aanee guddwar naliket vibhajit karate. mutrajanan sainasacha varcha bhag mutrashay tayar karato, tarr khalcha bhag mutramarg tayar karato.
ekatmik pranali.
tvachecha varvarchya thurr, epidermis, haah ectodermpasoon tayar hoto. dermis haah khol thurr messenkimepasoon tayar hoto.
bahyachashma tayar hone heey vikasachya aanee mahinyat suru hote aanee chauthya mahinyachya shevati tyachi nishchit vyavastha prapt hote. bahyajantu prushthbhagavar peshincha sapat thurr tayar karnyasathi vibhajit hoto jyala bahyajantu mhanatat. pudhil vibhajan bahyacharmache swatantra thurr tayar karate.
dermis tayar karnara messenkime teen strotanmadhun prapt hotoh
majjasanstha.
chauthya aathvadyachya uttaradhat, majjatantu nalikecha varcha bhag bhavishyatil madhya menduchya staravar cephalic flecture mhanoon ventrally vakato-messencephalone. messencephalone varr prosensephalone (bhavishyatil agra mastishk) aanee tyachya khalee rombensfallen (bhavishyatil pashch mastishk) aahe.
kapalatil majjatantu shikhar peshi majjatantu mool peshi mhanoon grasni kamanikade sthalantarit hotat, jithe tyaa majjatantuchya utpattichya prakriyet majjatantumadhye vikasit hotat.
prosensfalone besal platever optical vesical (jeey akheris optic majjatantu, retina aanee iris banate) tayar hote. prosensfalonechi alar plate vistarit houn cerebral golardh (telensfallan) tayar hote tarr tyachi besal plate dynesfallan banate. shevati, optic putika vadhat jaate aanee optic outgroth tayar hote.
bhautik vaishishtyancha vikas.
chehara aanee maan.
dolhe teey aathvya aathvadyaparyant chehara aanee maan vikasit hote.
qaan.
aateel qaan, madhala qaan aanee bahereel qaan heey vishisht garbhashastriy mool aahet.
aateel qaan.
vikasachya sumare 22 divasanni, rombensephalone donhi bajunvaril ectoderm jaad houn autic playcodes tayar hoto. heey playcodes sakriy houn autic khadde tayar karatat aanee nantar autic putke tayar karatat. nantar netratantuchya putke heey ventral aanee dorsal ghatak tayar karatat.
nilay ghatak sacule aanee coclear duct tayar karato. vikasachya sahavya aathvadyat coclear duct baher padate aanee aathvya aathvadyachya akheris 2.5 valane tayar hoiparyant sarpil aakarat pravas karat, sabhovatalachya messenkimemadhye pravesh karate. sacule haah ventral ghatakacha urvarit bhag aahe. teey arund ductus reunionsdware coclear ductshee jodalele rahate.
prushthbhagavaril ghatak utrical aanee ardhvartulakar kalve tayar karatat.
madhya qaan.
tympanic pokali aanee eustasian nalee hii pahilya grasni pishavipasoon (endodermane reshankit keleli pokali) ghetali jaatat. faticha durcha bhag, tubotympanic viram, tympanic pokali tayar karnyasathi rund hoto. faticha jawalcha bhag arund rahato aanee eustasian nalee tayar karato.
madhalya kanachi hadey, ausical, grasni kamanichya upasthinmadhun tayar hotat. mallius aanee incus heey pahilya grasni kamanichya upasthi pasoon udbhavtat, tarr steps heey grasni kamanichya aanee upasthi pasoon udbhavtat.
bahya qaan.
bahya shravanvishayak maans pahilya grasni fatyachya prushthbhagapasun vikasit hote. pahilya aanee aanee grasni kamanichya prushthbhagachya bajus messenkimal pravardhan asalelya sahaa auricular tekadya kanachya auricalchi nirmiti karatat.
dolhe.
dolhe dolhe aathvadyapasun dahavya aathvadyaparyant vikasit houu lagatat.
hatpay.
chauthya aathvadyachya shevati avayavancha vikas suru hoto. avyavanchya kalya sharirachya ventrolatoral pailuvar disatat. tyat ectodermcha bahya thurr aanee messenkimecha aateel bhag asato joou parshviy plate mesodermchya parital tharatoon tayar keela jaato. kalinchya durchya tokavaril ectodermal peshi epical ectodermal rij tayar karatat, jyamule vegane vegane messenkimal peshinche kshetra tayar hote jyala progress zoan mhanatat. upasthi (jyapaiki kahee shevati haad banatat) aanee snayu messenkimepasoon vikasit hotat.
vaidyakeey mahatva.
garbhachya kalavadhitil vishari sampark heey pramukh janmajat vikrutinche kaaran asoo shakate, kaaran pramukh avyav pranalinche purvavarti aata vikasit hott aahet.
pratyaropanpurv garbhachya pratyek peshimadhye vikasit vikasit garbhatil serve vegvegalya prakarchya peshi tayar karanyachi kshamata asate. yaa peshi samarthyacha arth assa aahe qee kahee peshi pratyaropanpurv garbhatoon kadhoon takalya jaau shakatat aanee urvarit peshi tyanchya anupasthitichi bharpai kartil. yamule purv pratyaropan anuvanshik nidan mhanoon olakhale jaanare tantra vikasit honyas parvanagi midali aahe, jyadvare aay. vhee. eff. dware tayar kelelya purv pratyaropan garbhatil thodya peshi bayopsidware kadhoon takalya jaau shakatat aanee anuvanshik nidanas adheen kele jaau shakatat. yamule paribhashit anuvanshik roganni prabhavit naan jhalelya garbhanchi nivad karata yete aanee nantar teey aaichya garbhashayat hastantarit kele jaau shakate.
sacrocosizal terratoma, vividh prakarchya uutinpasoon tayar honare tumour, jeey tayar houu shakatat, teey adim reshechya avasheshanshi sambandhit aahet asey manale jaate, jeey samanyatah nahise hotat.
pahilya kamaniche lakshan heey heey vikrutinche janmajat vikar aahet, jeey majjatantuchya shikhar peshinchya pahilya grasni kamanimadhye sthalantar karnyat ayashasvi jhalyamule hotat.
spina biphida haah janmajat vikar haah majjatantu nalika apoorn bund honyacha parinam aahe.
anulamb sankramit sansarg heey tyachya vikasachya konatyahi tappyavar aaikadoon naan janmalelya balala sankramit kele jaau shakatat.
hypoxia hii oxygenchya oxygenchya purvathyachi sthitee haah akali kinwa akali janmacha gambhir parinam asoo shakato.

