
plantazolycin

planazolycin (pii. zed. aine.) heey eka naisargik pratijaivik aahe jeey graam-positive maatee jivanu "basilus velezensis" eff. zeb. 42 (purvi "basilus amyeloliquifacians" eff. zeb. 42) dware tayar kele jaate. pii. zed. aine. heey visheshtah anthraxche karak ghatak asalelya "basilus anthrasis" viruddha sakriy asalele eka nivadak jivanunashak agent mhanoon olakhale gele aahe. heey naisargik utpadan ribosomally sanshleshit aanee anuvadanantar sudharit peptide (riip) aahe; tyache pudhe thyzol/auksajol-sudharit microsine (tomm) kinwa resheey ezol-yukt peptide (lapp) mhanoon vargikaran kele jaau shakate.
pii. zed. aine. chey mahatva tyachya sankuchit-varnapat pratijaivik kriyakalapanmule udbhavate. chikitsalayin vaparatil bahutek pratijaivike vyapak-spectrumchi asatat, jee vividh prakarchya jivanunviruddha karya karatat aanee yaa aushadhanna pratijaivik pratikar samanya aahe. yaulat, pii. zed. aine. heey "basilus anthrasis" saha keval thodya prajatinviruddha jivanurodhi aahe.
itihas.
pii. zed. aine. chya jaivasanshleshanasathi januke pahilyanda 2008 madhye nondavali gelee. tyanantar 2011 madhye naisargik utpadan 'basilus amyeloliquifacians' pasoon vegale karnyat aale. pii. zed. aine. chee rachana tyaa varshachya uttaradhat done swatantra sanshodhan gatanni, pramukhyane uchch-resolution maas spectrometry aanee aine. emm. aar. spectroscopidware sodavali. 2013 madhye, pii. zed. aine. chey vividh biomimatic rasayanik sanshleshan abhyas nondavale gele, jyat ekoon sanshleshan samavisht hote.
jaivasanshleshan.
 jivanunmadhye, plantazolycin (pii. zed. aine.) pratham raybosommadhye anuvadadvare aparivartit peptide mhanoon sanshleshit kele jaate. nantar anek ezol heterocycle aanee aine-terminal amine dimethylisations, peptidemadhye rasayanik badal karoon, anuvadanantarche badal sthapit karnyasathi enzymeschi eka malika tayar hote.
visheshtah, "buub" madheel pii. zed. aine. chya jaivasanshleshanadarmyan. velezensis', eka ribosomally-sanshleshit purvavarti peptide, cyclodidration aanee dehydrogenations, trimeric enzyme complexedware utprerit, anuvadanantar vyapak badalanmadhun jaato. hii prakriya cysteine aanee serine/threonin avasheshanche thyzol aanee (methyl) auksajol heterocyclemadhye (ujavikade pahilyapramane) rupantar karate.
aine-terminal leader peptide pradeshashi trimeric enzyme complexchya sambandhanchi achook yantrana adyap samajali gelee nahee; tathapi, asey manale jaate qee biosynthetic januk samoohamadhye asalelya peptidesdware leader peptide heey coor peptidepasoon nishchitpane vibhajit kele jaate. leader peptide kadhoon taklyanantar, navyane tayar jhalelya aine-terminusche methylation hote aanee tyamule eka peptide tayar hoto. yaa antim badalamule paripakv pii. zed. aine. hote.
basilus pumilus", "clavibacter mishiganances subsp yasarkhe itar jeev. sepedonicus, "corinebacterium urilaticum" aanee "bravibacterium linenance" heey samaan januk samoohansah olakhale gele aahet jyat pii. zed. aine. sarkhe renu tayar karanyachi kshamata aahe.