
integreen alfa 11

integreen alfa-11 heey eka prathine aahe, jeey manavanmadhye, "itga 11" janukadware encode kele jaate.
heey januk alfa integreenla sanketikrut karate. integreen hii alfa sakhali aanee beeta sakhalipasun banaleli heterodymeric integral membrain prathine aahet. yaa prathinanmadhye aay domain asate, snayunchya uutinmadhye vyakt kele jaate, beeta 1 integreen inn vitrosah diamerise hote aanee yaa swarupat collegenla bandhatana disate. tyamule, peshi peshi bahya koshikeey matrixshee jodanyat prathine sameel asoo shakatat. yaa janukasathi paryayi pratilekhan splies prakar sapadale aahet, parantu tyanchi jaivik vaidhata nishchit keleli nahee.
eka abhyasanusar, keratokonasamule prabhavit jhalelya dolhyanmadhun baher kadhalelya parpatalachya batananchya agravarti stromamadhe itta 11 abhivyakti vadhate. dusarya abhyasat asey disun aale aahe qee yakrut serosis, mootrapind fibrosis aanee fuffusachya fibrosis uutinsah vividh manvi tantumay roganmadhye myophibroblastmadhye itga 11 atiprabhavit hoto. swadupindachya ductal adenocarcinomachya tumour stromamadhe dekhil itga 11 niyantrit asalyache aadhalun aale aahe. manvi swadupindachya stellet peshinmadhye itga 11 khalee padalyamule tyanche myofibroblastmadhye farak aanee tumour peshinvar paracrine prabhav pratibandhit jhaala.