
ghan-tappa nishkarshan

solid-fages extraction (spay) heey eka solid-liquid extractive tantra aahe jyadvare drav mishranat virghalaleli kinwa nilambit keleli sanyuge tyanchya bhautik aanee rasayanik gunadharmannusar mishranatil itar sanyuganpasun vegali kelee jaatat. vishleshanatmak prayogshala vishleshanasathi namune kendrit karnyasathi aanee shuddha karnyasathi ghan tappyatil nishkarshanacha vapar karatat. mootra, rakt, paanee, peye, maatee aanee pranyanchya uutinsah vividh prakarchya matrixmadhun swarasya asalelya vishleshanatmak padarthanna vegale karnyasathi ghan tappyatil nishkarshanacha vapar keela jaau shakato. 
dravamadhye virghalalelya kinwa nilambit kelelya dravkanchya (jyala gatishil tappa mhanatat) sambandhancha vapar, jyachyadvare namuna pathavala jaato (jyala sthir tappa mhanatat), tyaa ghanasathi, ichchit aanee avanchhit ghatakanmadhye mishran vegale karnyasathi, spay vaparato. parinami ektar swarasya asalele ichchit vishleshan kinwa namunyatil avanchhit ashuddhata sthir tappyat thewali jaatat. sthir avasthetun jaanara bhag gola keela jaato kinwa fekala jaato, too tyat ichchit vishleshanatmak kinwa avanchhit ashuddhata aahe qee nahee yavar avalambun asato. jarr sthir tappyat thevalelya bhagamadhye ichchit vishleshanancha samavesh asel, tarr teey atirikt tappyat gola karnyasathi sthir tappyatoon kadhale jaau shakatat, jyamadhye sthir tappa yogya dravanane dhuun takala jaato. 
apoorn nishkarshan kinwa nishkarshanamule jhalelya spu dware vishleshakanchi apoorn punarprapti hone shakya aahe. apoorn nishkarshanachya babatit, vishleshkanmadhye sthir tappyabaddal pureshi aatmiyata nasate aanee tyancha kahee bhag pargamya raheel. apoorn allutionmadhye, vishleshakancha kahee bhag sharbatamadhye rahato kaaran vaparlelya alluentmadhye purese majboot aakarshan nasate. 
anek adhishoshak/sahitya heey chromatographic paddhatinpramanech aahet, parantu spay heey vishisht aahe, jyachi uddishte chromatographypasoon vegali aahet aanee mhanunach aadhunik rasayanik vidnyanat eka adviteey sthan aahe.
spay aanee chromatography.
spu aahe 
sarvat vyapak, sarvat sopya arthane vagalata, chromatography eka paddhat. heey eka nishkarshan tantra aahe, eka ghan-drav nishkarshan tantra aahe-ghan tappa aanee gatishil tappa yanchyatil mishra ghatakanchya keey. eae. kyu. kinwa samtol sthirankachya mothya farkancha fayda ghet, parinami, eka kinwa adhik mishra ghatakanchya mothya pramanat pruthakkaranamadhe, eka kinwa adhik mishra ghatakanchya mothya pramanat pruthakkaranasathi, jenekarun jalad nishkarshan prakriyecha parinam mhanoon teey lakshaniyaritya samruddha hoil. jarr asey manale gele tarr anek adhishoshak/sahitya heey chromatographic paddhatinpramanech asatat aanee jevha heey sahitya lamb stambhanmadhye pack kele jaate-jase qee parinami parimananusar saiddhantik plateschee sankhya vadhate-tyach samagrimule chromatographic vibhajan hote. jaree, spu aanee chromatography vibhajan karnari rakhadi resha, asey vegalepana heey sangnyaitke spasht aahe qee spu heey eka nishkarshan tantra aahe, siddhant, karyapaddhati aanee chromatographypasoon vegale uddishte aanee mhanoon aadhunik rasayanik vidnyanatil eka adviteey sthan aahe.
samanya tappyatil vishisht prakriya.
vishisht ghan avasthetil nishkarshanamadhye paach moolbhut payya asatat. pratham, kadtus dhruviy nasalelya kinwa kinchit dhruviy dravkashi samtol sadhala jaato, joou prushthbhag ole karato aanee bandhit tappyat pravesh karato. tyanantar silikyacha prushthbhag ole karnyasathi panyache kinwa namunyasarkhyach rachaneche buffer samanyatah stambhatoon dhutale jaate. tyanantar namuna kadatusemadhye jodala jaato. namuna sthir tappyatoon jaat asatana, namunyatil dhruviy vishleshak parasparkriya kartil aanee dravak aanee itar gair-dhruviy ashuddhata kadatusatun jaat asatana dhruviy sharbatavar tikoon rahtil. namuna bharalyanantar, pudhil ashuddhata door karnyasathi kadtuse dhruviy nasalelya dravkane dhuun takali jaatat. tyanantar, vishleshanatmak dravkache dhruviy dravak kinwa yogya piechchya buffers vilopan kele jaate.
dhruviy karyatmak bandh asalelya silikasacha eka sthir tappa, jyamadhye lahan carbon sakhalya asatat, too ghan tappa tayar karato. haah sthir tappa dhruviy renunna shoshun gheil jeey adhik dhruviy dravkansah gola kele jaau shakatat.
ulat fages spu.
ulat fages spu heey vishleshakanche dhruviyatechya aadhare vegale karate. ulat fages spay kadatusecha sthir tappa hydrocarbon sakhalyansah vyutpann keela jaato, jeey hydrophobic prabhavamule madhya teey qamee dhruviyatechi sanyuge rakhoon thevatat. kadtuse naun-pollar solventne dhuun analyty baher kadhali jaau shakate, jyamule analyty aanee sthir tappyacha parasparkriya viskalit hote.
carbon sakhalyansah siliconcha sthir tappa samanyatah vaparla jaato. pramukhyane gair-dhruviy, hydrophobic parasparsanvadanvar avalambun, keval gair-dhruviy kinwa atishay kamkuvat dhruviy sanyuge prushthbhagavar shoshali jaatil.
aayan vinimay spu.
aayan exchange sharbat heey sthir tappyatil swarasya asalelya vishleshakanchya aanee sakaratmak kinwa nakaratmak prabharit gatanchya vidyutsthaitik parasparsanvadachya aadhare vishleshake vegale karatat. aayan vinimay honyasathi, sthir tappa aanee namuna donhi phvar asane aavashyak aahe jethe donhi charge kelele aahet.
aayan vinimay.
aayan vinimay sharbat heey sakaratmak aaveshit karyatmak gatansah vyutpann kele jaatat jeey aamlasarkhya nakaratmak aaveshit ayanashi parasparkriya karatat aanee rakhoon thevatat. majboot aayan vinimay sharbatanmadhye chaturdhatuk amonium gut asatat jyancha jaleey dravnanmadhye kayamswarupi sakaratmak prabhar asato aanee kamkuvat aayan vinimay sharbat amine gut vapartat jeey ph sumare 9 peksha qamee asatana charge kele jaatat. majboot aayan vinimay sharbat upayukt asatat kaaran namunyatil konatihi majboot amleey ashuddhata sharbatala bandhali jaeel aanee sahasa vyaj asalelya vishleshanasah baher kadhali jaanar nahee; majboot aaml punarprapt karnyasathi kamkuvat aayan vinimay kadtuse vaparali pahijet. majboot kinwa kamkuvat sharbatatoon vishleshanatmak padarth kadhoon taknyasathi, sthir tappa eka dravkane dhuun takala jaato joou ektar vishleshanatmak, sthir tappa kinwa donhicha charge tatasth karato. ekada charge nishprabhavi jhalyavar, vishleshan aanee sthir tappa yanchyatil sthir vidyut parasparkriya aata astitvat nahee aanee vishleshan kadatusatun baher padel.
cashion exchange.
ketayan exchange sharbat heey karyatmak gatansah vyutpann kele jaatat jeey parasparsanvad sadhatat aanee bases sarkhya sakaratmak charge kelelya ketayanala rakhoon thevatat. majboot catayan exchange sharbansmadhye elephatic sulphonic acid gut asatat jeey jaleey dravanat nehmich nakaratmakpane charge kele jaatat aanee kamkuvat catayan exchange sharbansmadhye elephatic carboxylic acid asatat, jeey ph sumare 5 peksha jaast asatana charge kele jaatat. majboot catayan exchange sherbants upayukt asatat kaaran namunyatil konatihi majboot moolbhut ashuddhata sharbandhashi bandhali jaeel aanee sahasa vyaj vishleshanashi door kelee jaanar nahee; majboot bases punarprapt karnyasathi kamkuvat catayan exchange kadtus vaparali pahije. majboot kinwa kamkuvat sharbatatoon vishleshanatmak padarth kadhoon taknyasathi, sthir tappa dravkane dhuun takala jaato joou vishleshanatmak aanee sthir tappa yanchyatil ionic parasparsanvad tatasth karato.
kadtuse.
sthir tappa pack kelelya sirinjachya aakarache kadatus, 96 vihirichi plate, 47-kinwa 90-miimii sapat disk kinwa pack kelelya sharbat (emm. eae. pii. ess.) upkaranadvare sookshm nishkarshanachya swarupat yeto, eka vishesh paddhat jee drav hatalani sirinjmadhye pack kelelya sharbat samagricha vapar karate. heey tyachya vishisht prakarchya nishkarshanachya anek patanvar basavale jaau shakatat. manifold anek spay mediachya jaagi thevun aanee ekach velee samaan sankhyene namune tyanchya madhyamatoon jaanyachi parvanagi deuun anek namunyanvar prakriya karnyas anumati dete. manak kadatusemadhye 24 kadtuse samantar basavata yetat, tarr eka vishisht disk spay manifold 6 disk samavoon gheu shakate. bahutek spay manifolds vacuum portney susajj asatat, jithe sthir tappyatoon drav namuna khechoon nishkarshan prakriyes gatee denyasathi vacuum lagoo keela jaau shakato. sthir avasthetun gelyanantar vishleshanatmak dravpadarth anek patanchya aat kinwa khalee namune nalikanmadhye gola kele jaatat.
ghan tappyatil nishkarshan kadtuse aanee disk anek sthir tappyansah kharedi kelya jaau shakatat, jyapaiki pratyek vegvegalya rasayanik gunadharmannusar vishleshanatmak ghatak vegale karate. bahutek sthir tappyancha aadhar silika aahe joou eka vishisht karyatmak gatashi jodalela aahe. yapaiki kahee karyatmak gatanmadhye hydrophobic alkil kinwa eriel sakhali sakhali (ulat tappyasathi), chaturthansh amonium kinwa amino gut (aayan vinimayasathi) aanee elephatic sulphonic acid kinwa carboxyl gut (cashion vinimayasathi) yancha samavesh hoto.
ghan-tappyatil sookshm nishkarshan.
solid-fages microextraction (spme) heey eka solid fages extraction tantra aahe jyamadhye ark kadhanyachya tappyasah lepit fibercha vapar keela jaato, joou drav (polymer) kinwa ghan (sharbat) asoo shakato, joou vividh prakarchya madhyamanmadhun vividh prakarche vishleshan (asthir aanee asthir nasalelya donhisah) kadhato, jeey drav kinwa vayoo tappyat asoo shakatat. joparyant samtol gathala jaato kinwa alpakalin purv-samtol asel, tevha sanvahan kinwa halchalinchya madatine tantunni kadhalelya vishleshanatmak padarthache praman namunyatil tyachya ekagrateshi pramanbaddh asate.