avian coronavirus

avian coronavirus hii pakshyanna sankramit sankramit 'gamacoronavirus' vanshatil vishanuchi eka prajati aahe; 2018 pasoon, pakshyanna sankramit sankramit serve gamacoronavirusna hii ekmev prajati mhanoon vargikrut kele gele aahe. purvi sansargjanya bronchitis vishanu (aay. bii. vhee.) mhanoon olakhala jaanara avian coronaviruses prakar haah ekmev coronavirus aahe joou kombadyanna sankramit karato. hyamule avian sansargjanya bronchitis hoto, haah eka atyant sansargjanya rog aahe joou shwasanmarg, aatade, mootrapind aanee prajnan pranalivar parinam karato. aay. bii. vhee. maans utpadak aanee undy utpadak kombadyanchya kamgirivar parinam karate aanee kukkut udhyogatil lakshaniy aarthik nukasanasathi jababdar aahe. purvi turkey coronavirus mhanoon vargikrut kelelya avian coronaviruses prakar turkeymadhye jatharantra rogas karanibhoot tharato.
vargikaran.
aay. bii. vhee. haah 'gamacoronavirus' kinwa gut 3 madheel aahe, jyamadhye bigger-vibhagalele, sakaratmak-bhavna ekal-sapadalele aar. aine. aii. genome aahe.
purvi hii tyachya 'egakovirus' jaatichi prajati hotee. jevha coronaviruschi fakt ekach prajati hotee, 'coronavirus' hii prajati, tee serve dnyat coronaviruses gatachi prajati hotee.
punarsanyojan.
jevha coronavirus aay. bii. vhee. chey done prabhed yajmanala sankramit karatat tevha teey genome pratikrutichya darmyan punha ekatra yeu shakatat. nisargat nisargat aay. bii. vhee. janukanchya anuvanshik badalanmadhye punarsanyojan yogdan dett asalyache disate.
pathology.
shwasan pranali.
shwas aat gheta, tevha vishanu shwasan upkalakachya ciliated epithelial peshinvar siyalik aaml asalelya glycoprotein receptorsna jodel. shwasan pratikrutimule pitt kriyakalap, shleshmal sanchay, necrosis aanee disquemation qamee hoil, jyamule shwasan tras, reles aanee shwas gudmarane hoil. sthanik vishanuchya pratikrutimule viremia hoil, jyamule sansarg itar ootee aanee avayavanmadhye pasarel. kombadyanche itar shwasan rog (mycoplasma galicepticum, avian sansargjanya swarayantrashoth (gallid alphaharpisavirus 1), nucasal rog (avian paramixovirus 1), avian metapumovirus sansarg haah chikitsalayinadrushtya sansargjanya shwasanishoth assa gondhal houu shakato.
mootrapind.
viremiyachya madhyamatoon, kahee nephrotropic prabhed (bahutek uchch vishanu) nalika aanee nephronmadhil mootrapind epitheliumla sankramit karoo shakatat, jyamule mootrapind nikami houu shakate. sthool tapasanimadhye, mootrapind soojalele aanee fikat rangache aanee mutramargat mutramargasaha disu shakatat
prajnan pranali.
kombadyanmadhye, viremic aay. bii. vhee. dekhil andakoshaparyant pohochel, jyamule magnum (undy-pandhari granthi) aanee garbhashayat (undy-kavach granthi) jakhama hotil, jyamule andyache utpadan, kavach-virahit, najuk kinwa khadbadit kavach undy (garbhashayachi jakham) aanee panyache pandhare (magnum jakham) zapatyane qamee hotil. andakoshachya vikasadarmyan, tarunyamadhye kombadyancha sansarg, andakoshachya nirmitila adthala aanel aanee bhavishyatil bichhanachi kshamata nasht karel, parinami "khote thurr" tayar hotil. tathapi, thurr kombadyanna prabhavit karnare itar rog tyaa sthitila karanibhoot tharoo shakatat.
lus.
ksheen jhalelya lussy aanee nishkriy kelelya lussy yaa donhi upalabdh aahet. kharab cross-sanrakshanamule tyanchi parinamkarakta qamee hote. aay. bii. vhee. laa sanrakshanatmak rogpratikarak pratisad denyache swaroop farse samajale jaat nahee, parantu prushthbhagavaril spike prathine, amino-terminal ess 1 ardha, changli sanrakshanatmak pratikarshakti prerit karnyasathi purese aahe. prayogik vector aay. bii. lashee aanee aanuvanshikdrushtya hatalalelya aay. bii. vhee. ess.-heterologus spike prathin janukansah-ovo lasikaranachya sandarbhat aashadayak parinam dile aahet.

