exynucles

accessition endonucles, jyala exynucles kinwa yuu. vhee.-specific endonucles asehi mhanatat, heey eka nuclease (enzyme) aahe jeey dii. aine. aii. durustidarmyan nucleotidescha eka tukada baher kadhate. dii. aine. aii. madheel jakhamechya donhi bajunna asalele done phosphodister bandh hydrolyse karoon exynucles eka tukada kapate. hii prakriya "nucleotide cutting durusti" chaa eka bhag aahe, eka yantrana jee eukariotic peshi chakrachya jee 1 tappyat dii. aine. aii. laa vishisht prakarche nuksan bharoon kadhu shakate. asha nukasanamadhye yuu. vhee. kiranandware tayar kelele thymine diamer tasech sigaretchya dhurasarkhya strotanmadhun oxidised benzopyrenesmule dii. aine. aii. madheel avjad vikrutincha samavesh asoo shakato.
exynuclease kamatarata zeroderma pigmentosum navachya durmil autosomal recessive rogat udbhavate. yaa rogamule tvacha halki, kharkharit aanee aanee jakhama houu shakatat, tasech pyrimedine diamerchi durusti rokhata yete. raktatil raktatil raktpeshinmadhil enzymechi patali rakt namunyat mojoon yaa rogache nidan kele jaate. mulanmadhil lakshananmadhye atyant uv sanvedansheelata, jastiche daag padane, tvachecha anek karkarog aanee parpatalachya vranancha samavesh hoto. samanyatah, hii lakshane mulachya pahilya suryaprakashat disanyachya velee disun yetat.

