claustrum

claustrum (lattin, mhanje "bund karane" kinwa "bund karane") heey neuronsche eka patal patrak aahe aanee glial peshinna aadhar dete, jeey menduchya aachchadan aanee menduchya amigdala, hippocampus aanee thalamus subcourtical pradeshanshi jodate. heey anukrame atyant aanee bahya capsuldware vegale kelelya, parshvik aanee putamenchya madhyabhagi sthit aahe. madhya cerebral dhamnidware claustrumla rakt puravile jaate. hii mendutil sarvat datpane jodaleli rachana manali jaate aanee asha prakare drushti, dhwani aanee sparsh yasarkhya vividh cortical inputche ekach anubhavat ekikaran karnyas anumati denyasathi gruhit dharale jaate. itar gruhitak asey suchavatat qee parshva dhvanitil sarvat vartanukishi sambandhit uttejanankade laksh vedhanyasathi claustrum mukhya prakriyet bhoomika bajavate. claustral jakhama asalelya vyaktinchi maryadit sankhya aanee neuroimaging kharab resolution lakshat gheta claustrumcha abhyas karane katheen aahe.
claustrum haah aakar, aakar aanee neurochemical rachnet bhinn asalelya vividh prakarchya peshinni banalela asato. paach prakarchya peshi astitvat aahet aanee yapaiki bahutansh peshi aachchhadanat aachchhadanat pyramidal neuronsarkhya asatat. clostrummadhye, aachchadananchya tulanet peshinchya prakaranchi konatihi rachana nasate aanee peshinche shareer pyramidal, fuciform kinwa golakar asoo shakate. clostrummadhye aadhalanara mukhya peshi prakar mhanje golgi prakar I chey neuron, jeey spiony dendritesmadhye jhakalelya mothya peshi aahet.
aantar-golardhiy jodanidware, menduchya mothya pramanat vibhakt, parantu karyatmakdrushtya sambandhit bhaganmadhye (udaa.jee. pudhil dolhyanchi kshetre aanee drushya aachchadan). tyamule, jaanivela aadhar denyasathi sambhavyapane vividh mahitee paddhati ekatra karnyat claustrum bhoomika bajavate asey manale jaate. clostrumchi aanakhi eka prastavit karya mhanje sambandhit aanee aprasangik mahitimadhye farak karane jenekarun nantarchyakade durlaksh kele jaau shakate. chetanechya bahyabhagiy ghatakanmadhye fronto-parital cortex, singulate aanee precunus yancha samavesh hoto. yaa bhaganshi claustrumchya vyapak jodanimule, asey suchavale jaate qee teey laksh aanee jaaniv yaa donhimadhye bhoomika bajavu shakate. satat laksh aanee chetanemadhye madhyasthi karnare majjatantuche jaale claustrumla mahitee pathavtat aanee manavanmadhil eka prakaran ahavalat asey soochit kele aahe qee clostramjavalachya vidyut uttejanane rugnachya jagruk sthiteet ulat parinam hoto. 
rachana.
claustrum hii eka chhoti dwaipakshik rakhadi padarthachi rachana aahe (jyamadhye andaje cerebral cortexcha 0.25% samavesh aahe) jee insular cortex aanee atyant capsulechya kholvar sthit aahe aanee bahya capsule aanee besal gangliachya varvarchya bhagat aahe.
namood kelyapramane, tyachya navacha arth 'lapalele kinwa bund kelele' assa hoto aanee teey pahilyanda 1672 madhye olakhale gele, adhik tapshilvar varnan nantar 19 vya shatkat aale. jaree claustrumchya pradeshik neuroenatomical seema paribhashit kelya gelya asalya taree, tyachya achook maryadechi vyakhya kartana sahityat ekmat nasane kayam aahe, jaree 2019 madheel tadnyanchya baithakit eka chaukat tayar kelee gelee aahe jyadvare prajatinchya sanrachanancha sandarbh deela jaeel.
jodani.
20 vya shatkatil ahavalanchya prarambhik saranshat cortical input aanee aaootputvar bharr denyat aala. tathapi, nantarchya sanshodhanat asey suchavale gele aahe qee clostrumche cortical aanee subcourtical pradeshanshi vyapak sambandh aahet. adhik visheshtah, electrophysiological abhyas thalamic kendrak aanee besal gangliashi vyapak sambandh darshavtat, tarr isotopological ahavalanni claustrumla prefrontal, frontal, parital, temporal aanee ausipital corticeshi jodale aahe. atirikt abhyasanni claustrumcha subcourtical karananya padarthanchya marganshi asalelya changlya prakare varnan kelelya sambandhankade dekhil pahile aahe. corona radiata, ausiphitophrontal faciculus aanee unsinate faciculus prakalp yasarkhya sanrachana samoril, pericentral, parital aanee ausipital pradeshanmadhun claustrumla jaatat. motor, somatocensary, shravan aanee drushya cortical kshetranshi dekhil paraspar sambandh aahet. ekandarit, heey nishkarsh claustrumla mendutil prati pradeshik khand sarvat jaast jodaleli rachana mhanoon sodatat aanee asey suchavatat qee teey cerebral circuitschya kriyakalapanche samanvay sadhanyasathi kendra mhanoon kaam karoo shakate. yaa vyapak jodanisah dekhil, claustrumla yenare aanee tethoon yenare bahutek andaj heey ipecilatral asatat (jaree ajunahi parasparvirodhi andaj aahet) aanee menduchya tantu aanee pathichya kanyachya tyachya sanlagn kinwa aprabhavi sambandhanche varnan karnyasathi thode purave astitvat aahet. thodakyat, clostrumchi cortical aanee subcourtical jodani soochit karate qee tee sanvedi mahitivar prakriya karnyat, tasech pranyachya sharirik aanee bhavnik sthitimadhye sarvat jaast guntaleli asate.
microenatomy.
clostrummadhil input heey paddhatinusar aayojit kele jaatat, jyat drushya, shravan aanee somatomotor prakriya kshetrancha samavesh asato. jyaa prakare pathichya kanyachya rexed laminemadhil neuronsche aakarvidnyan karya darshavate, tyach prakare clostrummadhil drushya, shravan aanee somatomotor pradesh vishisht karyatmak vaishishtyansah samaan neurons samayik karatat. udaharanarth, drushya mahitivar prakriya karnara claustrumcha bhag ("pramukhyane aaplya paridhiy drushya kshetrashi sambandhit sanlagn tantunche sanshleshan") bahusankhya durbini peshindware banalela asato jyamadhye "dirghikrut grahansheel kshetre asatat aanee konatihi abhimukhata nivad nasate. paridhiy sanvedana pranalivar heey laksh kendrit karane hii eka vegali ghatana nahee, kaaran clostrummadhye pravesh karnare bahutek sanvedanatmak sambandh paridhiy sanvedanatmak mahitee aanatat. shivay, clostrummadhye pratyek sanvedanatmak paddhatisathi eka vegali topological sanghatana asate. udaharanarth, claustrumchya drushya prakriya kshetrat eka retinotopic sanstha aahe jee parshviy janukeey kendrakamadhil retinotopic sanvardhanapramanech (tarihi qamee klisht) paddhatine visual association courtices aanee vhee 1 chey pratibimb padate.
peshinche prakar.
claustrum vividh prakarchya peshinni banalela asato, jeey aakar, aakar aanee neurochemical rachnet bhinn asatat. clostrummadhil uttejak peshinche prakar done mukhya varg asatat jeey cortical aanee subcourtical menduchya bhaganmadhye bhinnapane prakshepit hotat. avarodhak neurons heey clostrummadhil neuronsche keval 10%-15% pratinidhitva karatat aanee tyat parvalbumin, somatostatin kinwa vasoactive aatadyansambandhi peptide vyakt karnare teen prakar asatat, jeey aachchhadanatil avarodhak neuronsasarkhech asatat. shevati, anek abhyas asey darshavtat qee pratibandhatmak peshi prakar vyakt pravesh parvalbumindware tayar jhalelya parvalbumin-positive fiberchya pramukh plexesdware claustrum sanrachanatmakdrushtya sarvottamaritya olakhale jaate.
undaratil vishleshan asey soochit karate qee aath prakarchya claustral peshi paach upprakaranchya uttejak pyramidal neurons aanee teen upprakaranchya avarodhak neurons astitvat aahet.
karya.
clostrummadhye asankhya cortical ghatakanchi vyapak kriya asalyache disun aale aahe, jeey serve chetaneche ghatak aanee satat laksh denyashi sambandhit aahet. yache kaaran mhanje front-parital bhag, singulate cortex aanee thalamishi vyapak sampark. singulate cortex, temporal cortex aanee thalamuschya jodanitun satat laksh dile jaate. 
crick aanee koch asey suchavatat qee clostrumchi bhoomika orchestramadhil vahakapramanech asate kaaran tee serve jodanyanchya karyat samanvay sadhanyacha prayatna karate. yaa "vahak" sadrushyala claustral, sanvedi aanee pudhil pradeshanmadhil jodnyandware dekhil samarthan dile jaau shakate. claustrum anukrame prefrontal cortex, visual, shravan, sanvedi aanee motor kshetranshi paraspar jodalela asalyachi pushti jhaali aahe. yaa paddhatinshi jodani claustrumchya karyakshamatebaddal antardrushti pradan karate. yethe asey prastavit kele aahe qee claustrum nivadak laksh denyachya gatingmadhye karya karate. yaa gating prakriyedvare claustrum yaa paddhatinmadhun input nivadakpane niyantrit karoo shakato jenekarun "phocus" karanyachi prakriya sulabh hoil. heey dekhil suchavale gele aahe qee teey ulat sandarbhat karya karate; vibhajan samanyikaranadvare claustrum "vichalit hone" rokhanyasathi vishisht input paddhatinna pratikar lagoo karoo shakate.
sambhavya karya.
claustrumla, jaaniv sulabh karnyasathi, aachchadanachya vividh bhaganmadhun vividh sanvedanatmak aanee gatishil paddhati ektrit karane aavashyak aahe. diffusion tensor imaging (dii. tii. aay.) vaparoon clostrumche sharirik sambandh pahile gele aahet. functional magnetic resonance imaging (eff. emm. aar. aay.) scan vishisht cortical bhaganchya kriyakalapanche nirikshan karnyacha eka marg mhanoon mendutil oxygenyukt rakt patalikade pahato. jevha undaranmadhye jaage asatana, visheshtah madhya purv-agrabhagachya aachchhadanala (emm. pii. eff. see.) aanee madhya-bahya thalamusla (emm. dii. thalamus) claustrum jodani, tevha eff. emm. aar. aay. scanmadhye damaleli kriya disun yete. claustrum heey majboot, karyatmak jodanisah, parasparvirodhi golardhatil clostrumshee jodalele aahe. emm. dii. thalamus, emm. pii. eff. see. aanee aaspaschya aanee durchya cortical bhaganshi dekhil sambandh aahet.
manjarichya prushthbhagachya clostrummadhil vidyut uttejana drushya aachchhadanamadhye uttejak pratisad dete. aachchadanchya vividh bhaganna jodanyasathi vaparlya jaanarya mothya sankhyene karananya-padarthanchya marganchya sangmavar claustrum sharirikdrushtya sthit aahe. heey pudhe sanvedanatmak aanee motorsarkhya yaa vegvegalya paddhatinsathi ektrikaran kendra bhoomika suchavate. claustrumchya espiny interneurancemadhye antar junction astitvat asalyache darshavile gele aahe-input prapt hott asatana yaa paddhatinna samkramit karnyachya kshamatemadhye bhoomika suchavate.
atirikt abhyas sthanik dishadarshan aanee mand-lahari zopetil sahbhagakade nirdesh karatat
laksh dya.
nirdeshit laksh denyasathi sambandhit mahitee aanee aprasangik mahitee yapaiki nivad karanyachi kshamata vargamadhye asate. tyat aachchhadanatil karananya padarthanchya marganna jodanyachi sarvadhik ghanata asate. heey menduchya vividh bhaganmadhye networking aanee samanvayachya kalpanela samarthan dete. clostrummadhye pradeshik vishishtata asate; drushya kendranmadhun prakalpatoon sanrachanetil rakhadi padarthachya neuronschya vishisht bhaganmadhye aanee shravan aachchhadananmadhye yenari mahitee. anpekshit uttejananmule claustrum dekhil sakriy hoto, jyamule karyavar twarit laksh kendrit karane kinwa tyache vatap karane prabhavit hote. qamee sastan pranyanmadhye (udaa.jee. under), claustral pradeshanna yaa sastan pranyanmadhye tyachya sanvedanatmak aanee bhedbhavpurn vaparamule munchhanchya motor niyantran drushtikonatun somatocensary paddhatinmadhun input milate. 
karyatmakdrushtya, heey prastavit kele aahe qee teey yaa paddhatinmadhye laksh vegale karate. laksh dene heey swatah varchya-khalchya prakriyeche kinwa khalchya-varchya prakriyeche manale gele aahe; donhi clostrummadhye jeey pahile jaate tyachyashi sanrachanatmak aanee karyatmakdrushtya susangat aahet, jeey encoding objects aanee vaishishtyanmadhye samavisht asalelya uchch-kram sanvedi kshetranshi parasparsanvad hoto yaa kalpanela samarthan detat. udaharanarth, prefrontal cortexmadhun milanare input, uchch-sandnyanatmak karya-chalit vartanavar aadharit laksh paribhashit karel. shivay, clostrummadhye vidyut uttejanacha samavesh kelyane avarodh vachan, eka rikt najar aanee pratisad naan dene asey disun aale aahe. asey nondavale gele aahe qee clostrummadhye besal frequency firing asate jeey nirdeshit laksh deuun vadhanyasathi kinwa qamee karnyasathi modulate kele jaate. udaharanarth, motor aanee auculomotor kshetrantil andaj claustral neuronschee aag lagnyachi varanvarta vadhavun naveen uttejanankade laksh vedhanyasathi najarechya halchalis madat kartil.
salvia divinorammadhe aadhalanare sakriy matibhramjanya sanyug salvinorin aii, jagrukta qamee karnyas pravrutt karnyas saksham aahe. salvinorin aii chey sevan cinesthesia prerit karoo shakate, jyamadhye vegvegalya sanvedanatmak paddhati vegvegalya sanvedanatmak aachchhadanandvare samajavun ghetalya jaatat. (udaharnarth aavaj pahane, rung chakhane.) heey intrathalamic pruthakkaran aanee wahan (laksh) yaa kalpanela samarthan dete. clostrummadhye kappa opioid receptors asatat, jyanchyashi salvinorin bandhale jaate, jyamule haah parinam disun yeto.
anubhavjanya purava.
manjar clostrummadhil (ess) uchch varanvarta uttejanamadhye (etch. eff. ess.) swayatt badal prerit karanyachi aanee "nishkriyata lakshansamuchchay" prerit karanyachi kshamata asate. yaa lakshansamuchchayala jaaniv qamee hone asey varnan kele jaate, jeey claustrum aanee chetana yanchyatil sambandh darshavate. manavanmadhye haach parinam disun yeu shakato. manavanmadhye davya claustrumchya uttejanane 'nakaratmak motor lakshane kinwa keval afesiyashivay swaichhik vartan, pratisad naan dene aanee vismaran purnapane bund karane' tayar kele aahe jeey chetanetil sahbhag soochit karate. yavyatirikt, emm. aar. aay. abhyasanni asey darshavile aahe qee clostrummadhil signalchi vadhati tivrata sthitee epilepticshi sambandhit aahe-eka ashee sthitee jyamadhye epilepticche daure ghatananmadhye chetana punarprapt naan karata ekmekanchya mage yetat. tasech, signalchi vadhaleli tivrata hii phokal discognitive sizarashi sambandhit aahe, jeey asey seasure aahet jeey aakadi naan yeta jagrukta kinwa chetanechi kamjori nirman karatat. vyaktila tyachya kinwa tichya vatavaranachi jaaniv hott nahee aanee hii japti eka khidakitoon eka rikami kinwa rikami najar mhanoon disun yeil.
claustrumchya etch. eff. ess. saha ektritpane karyarat anukulan karya vaparnyamule undaranchya vartanat lakshaniy badal jhaale; yamadhye modulated motor pratisad, nishkriyata aanee qamee pratisadatmakata yancha samavesh hota. (kaubesi ref joda) hyapalikade, abhyasanmadhye asehi disun aale aahe qee dentate gayarasasarkhya itar sanrachanansah, raim sleep darmyan claustrum sakriy asato. yaa kshetranmadhye kahee pramanat smrutee ektrikaran hote asey soochit karat, sthanik smrutimadhye hyachya sahyogi bhoomika aahet.
jakham aanee jaaniv.
karyatmakdrushtya, claustrum tyachya jodnyandware vividh cortical input chetnamadhye samakalit karel. tyachi rachana aanee sampark sadhanyachya aadharavar, tyache karya menduchya vegvegalya karyanchya samnvayasah kele jaate asey suchavale jaate;eae. vahak sadrushya. jaaniv hii karyatmakdrushtya done ghatakanmadhye vibhagali jaau shakateh (i) jagruti, jee uttejana aanee satarkata aahe; (ii) chetanechi samagri, jee samagrichi prakriya aahe. clostrumchi karyatmak bhoomika adhik changlya prakare samajoon ghenyasathi yuddhatil diggajanmadhye menduchya aaghatatmak dukhapatincha abhyas haatee ghenyat aala. clostrumche nuksan heey chetanechya hanichya kalavadhishi sambandhit hote, parantu varanvarteshi nahee. jakhamecha aakar sthanik ghatananchya adhik kalavadhishi sambandhit hota. sandnyanatmak prakriya qamee karnyasathi konatehi parinam disun aale naheet.
ekach prakaran-abhyasat, menduchya atyant capsulela-jeey claustrumchya jawal aahe-jevha uttejana hote tevha chetana viskalit jhalyache disun aale-mhanje uttejana sampalyanantar, chetana parat prapt jhaali. schizophrenia lakshanshastrakade lakshanshastrakade aanakhi eka abhyasane asey siddha kele qee bhramanachi tivrata davya claustrumchya qamee jhalelya rakhadi padarthachya pramanashi sambandhit hotee; yaa mansik vikarat disanari rachana aanee sakaratmak lakshane yanchyat parasparsambandh astitvat aahet asey gruheet dharale. schizophrenia aanee claustrum yanchyatil yaa parasparsambandhala aanakhi aadhar denara mhanje clostrummadhye pravesh pravesh karananya padarthanchya pramanat vaadh jhaali aahe. schizophrenia shravanvishayak matibhramanchya sandarbhat, dhusar padarthache praman aanee matibhramanchi tivrata yanchyatil ulat parasparsambandhanna samarthan denyat aale aahe. tasech, claustrumchya karyat ekoon haanee pahanyasathi, pratyek golardhatil donhi claustrumchya jakhama hone aavashyak aahe. 
tathapi, 2019 madhye, claustrumchya vidyut uttejanasah kelelya abhyasat, vishleshanas patra asalelya paach rugnanpaiki konatyahi rugnanmadhye chetanet konatahi vyatyay aadhalala nahee. chachani kelelya rugnanni vividh sanvedanatmak kshetrantil vyaktinishth anubhavanchi nond kelee aanee pratikshipt halchal darshavili, parantu tyanchyapaiki konihi jaaniv gamavalyache darshavile nahee, asha prakare vidyut uttejit jhalyavar chetana viskalit karnyachya claustrumchya kshamatevar prashnachinh upasthit kele.
vaidyakeey mahatva.
schizophrenia.
clostrumche nuksan vividh samanya rog kinwa mansik vikaranchi nakkal karoo shakate; sanrachanecha vilambit vikas swalinateshi sambandhit asalyache disate. claustrum schizophreniamadhye sameel asoo shakato kaaran nishkarsh sakaratmak lakshananmadhye vaadh darshavtat, jase qee bhram, jevha davya claustrum aanee ujavya insulache rakhadi padarthache praman qamee hote.
apasmaracha tras.
apasmarachya rogat claustrum dekhil bhoomika bajavtana disun yete; jyaa vyaktinna apasmarache nidan jhaale aahe, tyamadhye claustral signalchi tivrata vadhali asalyache misesala aadhalale aahe. kahee prakarananmadhye, suruvatichya kainik acid prerit zatkyanmadhye sameel asatana, khilkhilepanacha ugam clostrummadhun hoto asey disate.(kaubesi ref joda)
jaaniv.
eka cases-studdyne dakhavun dile qee jevha insula aanee clostrummadhil kshetra vidyut uttejit hote tevha chetana viskalit hote; jevha uttejana thambali tevha chetana parat prapt jhaali. jyaa rugnanna tyanchya davya clostermadhye jakham jhaali hotee, tyanna claustrumchya baher jakhama jhalelya rugnanchya tulanet chetanecha chetanecha honyachi shakyata jaast hotee. udaharanarth, clostrumwer electrode uttejanala samore gelelya rugnane vachan thambavale, rikame pahile aanee too pratisad dett navhata. ekada electrode kadhoon taklyanantar rugnane punha vachan suru kele aanee aashcharyachakit honyachya ghatana tyala aathavat navhatya. 
claustrumchya vidyut uttejanancha samavesh asalelya 2019 chya abhyasat vishleshanas patra asalelya paach rugnanpaiki konatyahi rugnanmadhye chetanet konatahi vyatyay aadhalala nahee. chachani kelelya rugnanni vividh sanvedanatmak kshetrantil vyaktinishth anubhavanchi nond kelee aanee pratikshipt halchal darshavili, parantu tyanchyapaiki konihi jaaniv gamavalyache darshavile nahee, asha prakare vidyut uttejit jhalyavar chetana viskalit karnyachya claustrumchya kshamatevar prashnachinh upasthit kele.
2020 chya abhyasat optogenetic prakash uttejanadvare claustrumchya krutrim sakriyatecha samavesh aahe, sampoorn aachchhadanamadhye menduchi kriya shant kelee gelee, hii eka ghatana "daun steet" mhanoon olakhali jaate, jee under zopalele asatana kinwa jaage asatana vishranti ghet asatana (shant jagruti) pahili jaau shakate. lekhak mhanatat qee 'claustrum haah jaagtik santh-lahari kriyakalapancha samnvayak aahe aanee heey itake romanchak aahe qee aapan menduche vishisht sambandh aanee krutee chetanachya antim kodishi jodanyachya jawal jaat aahot.
parkinsonvad.
beth israyalachya deconness vaidyakeey kendratil neuroscientischya netrutvakhalil tapaskartyanchya chamoone vegvegalya paristhitinmadhye parkinsonvadache sambhavya mool mhanoon clostrummadhil jakhama olakhalya aahet. yaa chamoone parkinson rogacha parinam nasalelya, parantu menduchya jakhmeshi sambandhit asalelya 29 rugnanmadhye parkinsonvadachi utpatti shodhanyasathi jakhamechya jaalyache mapping navachi eka naveen paddhat vaparali-menduchya imagingwar disanari menduchi vikrutee kinwa dukhapat. menduchya vegvegalya bhagat asalelya 29 jakhamanchya nakashavarun asey disun aale qee clostrumshee jodani hii jakham-prerit parkinsonvadachi ekmev sarvat sanvedanshil aanee vishisht chinhak hotee.
chinta aanee tanav.
undaranmadhye, clostrumche dadpan chinta/tanav qamee karate aanee dirghakalin tanav-pratikar vadhavate.
itar prani.
pranyanmadhye, margikecha magova ghenyachya madhyamatoon, nishkarshanni asey darshavile aahe qee clostrumche hippocampus sanvedi aanee motor kshetranshi sampoorn aachchhadanamadhye vyapak sambandh aahet. manjar, undeer aanee makade yasarkhya vividh pranyanchya pratikrutincha vapar keela gela aahe. 
manjari.
manjarinmadhye, clostrumche uchch-varanvarta uttejan (etch. eff. ess.) motor kriyakalap badaloo shakate, swayatt badal prerit karoo shakate aanee 'qamee jagrukta' mhanoon varnan kelelya 'nishkriyata lakshansamuchchay' laa veg deu shakate. pramukhyane manjar aanee narvanar pranyanmadhye nondavalelya nondi darshavtat qee claustral neurons sanvedanatmak uttejananna aanee aichchhik halchalinchya darmyan pratisad detat. visual cortexpasoon clostrumparyantchya mappingmadhe fakt ekach nakasha samavisht aahe, jyamadhye vhee 1 aanee itar teen visual kshetrancha samavesh aahe. aahe madheel peshi 6 vya tharacha bhag asatat, jyaa parshviy janukeey kendrakat kendrakat peshinpeksha bhinn asatat; yaa peshi glutamatecha tyancha neurotransmitter mhanoon vapar karatat. manjar clostrummadhye 3 paribhashit kshetre aaheth (1) motor aanee somatocensary cortexshee jodale jaanare agravarti prushthbhagache kshetra, (2) prushthbhagache prushthbhagache kshetra jeey drushya aachchhadanshi jodale gele aahe aanee (3) eka truteey kshetra jeey drushya aachchadan aanee shravan kshetrashi jodale gele aahe.
sanvedi input heey paddhatinchya aadhare vegale kele jaate aanee paridhiy sanvedi mahitila uchch pradhanya dile jaate. manjaramadhye, vividh drushya aachchadan kshetranmadhun aanee prakalpanmadhun tyaa bhagat parat input prapt hote. heey loop retinotopical aahet, mhanje drushya input midavanare pradesh drushya kshetratil tyach pradeshasathi jababdar aahet jeey aachchadanchya kshetrasathi jababdar aahet jeey claustrumla prakshepit karatat. visual claustrum haah virodhabhasi visual ardhakshetracha ekach nakasha aahe, joou visual fieldchya parighatil gativar aadharit mahitee prapt karato aanee tyat konatihi vastavik nivad nasate. somatosensation babatit, manjar claustrumla prathamik somatocensary cortex (ess 1) pasoon ghan input milate, parantu duyyam somatocensary cortex (ess 2) pasoon kamkuvat input milate. claustrumla madheel input prathamik motor cortexmadhil inputs (kiman donhichya agrabhagachya pratinidhitvatil) overlap hotat. kruntak claustrumla claustrumla kinwa kinwa pasoon input milat nahee aanee too pramukhyane motor cortexdware chalavala jaato.
kruntak.
undaranmadhye, motor viskar bhagat ipsilateral clostrummadhun input milate parantu nantar teey contralateral clostrumwer prakshepit hoil. sanvedi naliche aachchadan aanee prathamik drushya aachchadan dekhil ipsilateral clostrummadhun input prapt karatat parantu clostrumwer parat phaar qamee prakshepan pathavtat. tyamule abhyas vegvegalya cortical kshetranshi claustrumchya jodaniche vegale swaroop darshavtat. heey soochit karatat qee, pasarlelya bhoomikeaivaji, teey cortical prakriyet vishesh bhoomika bajavtat. 
undaranmadhye, parvelbumin tantu rasayanik aanee vidyut synapsdware atyant ekmekanshi jodalele asatat. yavyatirikt teey claustrocartical neuronshee dekhil atyant ekmekanshi jodalele aahet-asey soochit karate qee heey avarodhak interneurons tyanchya kriyakalapanna jordarpane sudharit karatat. heey sthanik jaale menduchya vividh cortical bhaganchya menduchya talavar aanee samanvit kriyakalapanvar prabhav taknyasathi claustrocortical andajanchya kriyakalapanna samkramit karnyache suchavatat. claustrocartical neuronsmadhye sthanik jodanisah avarodhak interneurance atirikt varg aahet.
badalatya drushya uttejananparyant claustrocartical akshatantunchya kriyakalapanvar dekhrekh dekhrekh undaranmadhil prayog heey claustrum signalchya uttejanatil badal soochit karatat. jaree drushya aachchadan kshetransathi claustrocortical input guntalele asale taree, mojale gelele sarvat majboot pratisad aachchadanchya uchch-kramatil bhagat hote, yamadhye agravarti singulate aachchadan samavisht hote jeey claustral prakshepanadvare datpane majjatantu hote.
makade.
makadamadhye, clostrumche allocartical aanee neocortical pradeshanshi vyapak sambandh aahet. heey jodane pudhil bhag, drushya aachchadan pradesh, tatpurte aachchadan, parito-ausipital aachchadan aanee somatocensary kshetransarkhya itar bhagankade prakshepit karatat. amigdala, coddet nucleus aanee hippocampus hii anumane prapt karnari upcortical kshetre aahet. clostrummadhun input naan milanare cortical kshetra aahet qaa heey adnyat aahe. yavyatirikt, makadachya mendut mothya kinwa lahan prakarchya espiny aadhaltat, jyanna "sthanik paripath neurons" mhanoon vargikrut kele jaate.
prushthiy clostrumche aachchhadanatil motor sanrachananshi dvi-dishatmak sambandh asatat. pranyanchya halchali aanee dorsocadal clostrummadhil neurons kase vagatat yamadhil sambandh khalilpramane aaheth 70 takke halchal neurons nivadak nasatat aanee agrapatalat konatyahi dhakka, khechane kinwa valan halchali karnyasathi phayar karoo shakatat, urvarit adhik viveki hote aanee varr soochibaddha kelelya teen halchalinpaiki keval eka karat hote.

