crest syndrome

crest syndrome, jyala systemic sclerosischa (ell. see. ess. see.) maryadit tvachecha prakar mhanoon dekhil olakhale jaate, haah eka bahu-pranali sanyojak ootee vikar aahe. crest' heey sankshipt naav paach mukhya vaishishtyancha sandarbh deteh calcinosis, reynades phenomenon, annanaliketil dismotility, sclerodactyly aanee telangiactasia.
crest syndrome haah centromerase (peshi kendrakacha eka ghatak) viruddha shodhanyayogya pratipindanshi sambandhit aahe aanee sahasa mutrapindanna vachavato (sambandhit pranaligat sclerodermachya sthitimadhye eka vaishishtya adhik samanya aahe). fuffuse guntaleli asalyas, tee sahasa fuffusanchya dhamnitil uchch raktadab swarupat asate.
chinhe aanee lakshane.
calcinosis.
calcific nodules ("calcinosis") jamaa jhalyamule shikharamule tvacha ghatt hote aanee ghatt hote.
renaudchi ghatana.
reynoudchi ghatana hii bahudha crest/ell. see. ess. see. chee pahili abhivyakti asate, jee itar lakshananpeksha varshanuvarshe aadhi asate. taana aanee thund tapmanamule aakadyanchya tvachechya lahan dhamanyanche, dhamanyanche aanee thermoregulatory vahinyanche atishayoktikaran hote. vaidyakiyadrushtya heey tvachechya rangat pandhare-nile-laal sankraman mhanoon disun yete. yaa sankramanachya antargat ankanche paller aanee cyanosis aahe, tyanantar teey punha garam hott asatana pratikriyashil hypermia hoto. jevha tivra aanee varanvar, yaa ghatanemule digital vran, gangreen kinwa angvichedan houu shakate.
vranamule sambandhit jagechya junat sansarg honyachi shakyata asate.
annanaliketil aswasthata.
annanalikechya madhya kinwa khalchya bhagat ann adakalyachi (dysphagea) jaaniv, chhatimadhye asamanya vedna kinwa khokala ashee hii bhavna asate. ghan ann gilanyasathi dravpadarth pyayala havet asey lock anekada sangatat. hii halchal samasya jatharantramargachya bhintivaril gulgulit snayunchya kshinatemule udbhavate. haah badal lakshaniy ootee tantumayatechya rogshastriy puravyasah kinwa tyashivay houu shakato.
sclerodactly.
jaree heey sarvat sahaj olakhata yenyajoge prakatikaran asale taree teey serve rugnanmadhye pramukh nahee. jaad honyamadhye samanyatah fakt botanchi tvacha, jee shikharavaril metacarphophalengeal sandhyanpasun door asate, tee samavisht asate. rogachya suruvatilach, tvacha sooj aanee soojaleli disu shakate. akheris, tvacharogiy tantumay sphot bahyakoshikiy matrixche jaast utpadan karatat jyamule tvachemadhye uutinmadhye collegen jamaa hone vadhate. collegen cross-linkingmule nantar tvacha uttarottar ghatt hote. digital ischemic alsar samanyatah rugnanchya 30-50% madheel durchya botanvar tayar hotat.
telangiactasia.
chinhankit telangiactasia (vistrut keshika) keshika) tvachevar, hatanchya pamar prushthbhagavar aanee shleshmal patalavar hotat. itar scleroderma sambandhit raktavahinyasambandhi rog asalelya lokanmadhye (i.eae.fuffusiy dhamani uchch raktadab). telangiactasiachi sankhya aanee tyat samavisht asalelya thikananchi sankhya kalantarane vadhanyacha cull asato...
itar.
crest syndromechi itar lakshane mhanje thakwa, ashaktapana, shwas ghenyas tras hone, haat aanee paay dukhane, chakkar yene aanee jakhama white prakare barey hone.
ell. see. ess. see. asalele rugna samanyatah fuffusiy dhamani uchch raktadabas pravrutt karatat jyamule coor fuffusiy (fuffusiy dhamanicha vadhalela daab yamule hriday nikami hone) houu shakate.
kaaran.
crest syndromedhye svayampratikar virodhi anoo-aanee virodhi centromere pratipinde tayar karane samavisht aahe, jaree tyanche kaaran sadhya samajale nahee. sansargjanya kaaran maheet nahee.
nidan.
crestche nidan sahajpane kele jaat nahee kaaran teey itar sanyoji ootee aanee svayampratikar roganchya lakshananche barkaine anukaran karate. nidan sahasa tevha kele jaate jevha ekhada rugna paach pramukh vaidyakeey lakshananpaiki done kinwa adhik lakshane darshavito. yavyatirikt, sakaratmak anas chachanisathi rakt chachanya dilya jaau shakatat aanee nidanala pushti denyasathi madat karnyasathi aii. see. aii. ess. kinwa tvachechi biopsy dilee jaau shakate.
upchar.
rogpratikarak shakti qamee karane aanee itar aushadhanmule rogachi pragati mandavali jaau shakate aanee annanaliketil refluxes, fuffusiy uchch raktadab aanee reynoud ghatanecha lakshaniy upcharanmule fayda houu shakato. tathapi, yaa rogavar konatahi upchar nahee kaaran sarvasadharanpane sclerodermaver konatahi upchar nahee.
mahamarishastra.
prathamik pittashayatil colangitis asalelya 10 takkyanparyant rugnanmadhye crest syndromechi nond houu shakate.
itihas.
lakshane ektritpane pahilyanda 1964 madhye aar.etch. winterbaur, tyaa velee johns hopkins school auph medicinemadhil vaidyakeey vidyarthi.

