
christopher marshell (doctor)

instittyoott oof cancer researchil cancer biology division director pravarthicha oru britiish shaasthranjanaayirunnu christopher joonn marshell eph. eph. emm. ezz. sii (19 januvari 1949-8 august 2015). tumour sell signalling mekhalayile gaveshanathinu marshell verthiricharinju. addehathinte track recordil "enn-raas" oongoojen kandethal ulppedunnu.
raas proteinukalude farnesilation thirichariyal, mapp/erc paathayiloode raas signal nalkunna kandethal. eee kandethalukal raas farnesilation, meck, bii-raaf ennivayude inhibittarukalude chikitsa vikasanathilekku nayichu.
aadyakaala jeevitam.
marshell yukeyile birminghamil janikkukayum king henry VIII school, coventriyil vidyaabhyaasam nedukayum cheythu. thudarnnu addeham kembridge sarvakalashaalayil prakrithishaasthravum thudarnnu ooksfoord sarvakalashaalayil sell biologyil defill padichu. addehathinte birudapatanathe thudarnnu landanile linkens inn feeldukalileyum (ippol francis crick instittyoottinte bhagamaaya) bosttanile daana-farber cancer instittyoottileyum imperial cancer research fund laborattarikalil poost doctoral jolikal nadatthi.
oongoojen gaveshanam.
1980-ll marshell landanile instittyoott oof cancer researchilekku maarukayum manushya cancer jeenukal thirichariyunnathinulla padanangal aarambikkukayum cheythu. eee jolie, addehathinte sahapravarthakanaaya alan haalumayi sahakarichu, oru puthiya manushya oongojeenaaya nraasine thirichariyaan kaaranamaayi. addehathinte laboratariyil ninnulla thudarnnulla padanangal kaanikkunnath rakthaarbudhathil nassinu pradhana pankundennum mattullavar melanomyil naassinte punk prakadippichuvennum. naassine thiricharinjathinethudarnna, nasses mattu rund raas jeenukalaaya haas, crass enniva canceril engane pravarthikkunnuvennu padikkunnathil marshell shradha kendreekarichu. koshathinu purathu ninnu kosha nucleusilekku signalukal kaimarunnathil raasum mattu signalling proteinukalum engane ulppedunnuvennu sell signalling mekhalayile addehathinte pravartthanangal kaanichu. melanomyil "braf" cancer jeeninte praadhaanyam kaanikkunna padanangalkku addehathinte pravartthanangal aditharayittu.
addehathinte maranasamayathu, maarshalinte laborattari shareerathiloode cancer koshangal pakaraan anuvadikkunna sell signalling samvidaanangal padichu. prathyekichum, eee padanangal cheria jidipesukalude raas, roow kudumbam niyanthrikkunna signal transduction pathakalil shradha kendreekarichu.
vidyaarthikalum poorvva vidyaarthikalum.
professor maarshalinte laboratariyil pariseelanam nediya niravadhi poost doctoral fellomar biruda vidyaarthikalum abhimaanakaramaaya sthaanangalilekku pooyittunda

