
elisabath pii. marappanikkaaran

elisabath pii. ooksfoordile nafield department oof medisinil professoraaya oru britiish structural biologistaanu marappanikkaaran. ex-reey christalography upayogichu manushya membran proteinukalude trimana ghadana avar pariharichu. proteinukalkkullile aattomik sthaanangal manasilakkaan marappanikkaaran ex-reey christalography upayogikkunnu.
aadyakaala jeevithavum vidyaabhyaasavum.
marappanikkaaran cambridge sarvakalashaalayil biochemistry padichu. doctoral gaveshanathinaayi avar lunden sarvakalaashaalayile birkbekkilekku thamasam maari, avide avar biochemistry chrystallography padichu. doktarettu poortthiyaakkiya sesham, marappanikkaaran landanile imperial koleju aasthaanamaayulla naashanal instittyoott phoor health researchilekku maarukayum dna attakuttappanikalil ulppedunna proteinukalude gadanakal pariharikkukayum cheythu. toxoplasmosis, mastti chalanam ennivayum avar parishodhichu.
gaveshanavum thozhilum.
proteinukalude ghadanayum pravartthanavum manasilakkaan marappanikkaaran thaalpparyamund. kosha stharangalil ulchertha proteinukalekkurichu avar padikkunnu. proteinukal valia hydrophobic prathalangalaanu, avayude ghadana manasilaakkunnath kosha stharangaliludaneelamulla thanmaathrakaludeyum signalukaludeyum prakriyakal anaavaranam cheiyunnathinulla oru pradhana gattamaanu. 2007ll diamond laitt sozhsil membran protein laborattari sthaapichu. 2009ll ooksfoord sarvakalaashaalayile structural genomics kansorshyathilekku maari.
manushya abc-transporter abc 10-nte ghadana aadyamaayi vivarichathu marappanikkaaranaan. abc 10 ennathu heeminte ulppaadanathil pradhaanamaaya oru mitrocontidal proteinaan. laaminukalude proteinukalude parajayam moolamundaakunna akaala vaardhakya lakshanangalum metalloprotes isad. emm. pii. ezz. tii. iii 24-nte pankum avar padichu. membran pottensialinu kaaranamakunna pashchaathala chorchaykku kaaranamakunna keey2pii proteinaaya trekk-2 ulppedeyulla manushya ayoon chaanalukalum avar padichu.

