arbutus biopharma

liposomal marunnu vitharanathilum rna edapedalilum vaidagdhyamulla pothuvaayi vyapaaram nadathunna canadian (nasdaca abus) biopharmaceutical kambaniyaanu arbutus biopharma korppareshan, koodaathe heppattaitis bii anubaadhaykkulla marunnukal vikasippikkukayum cheiyunnu.
pensylvaniayile vorminstarilaanu ithinte aasthaanam. 2007ll ink farmaceuticalsil ninnu verthirichedutha tekmira ennaanu kambani munbu ariyappettirunnath.
charithram.
2004ll niyanthrana, pankaalittha thanthram paraajayappettathinetthudar kambani thakarnnuthudangiyathinu sesham 2005ll inx faarmasyoottikkalsinte poornna udamasthathayilulla anubandha sthaapanamaayi tekmira roopeekarichu. 2007ll tekmeera poornnamaayum verpeduthi, 1992ll sthaapithamaaya inksinte asthikal tekmeera ulkkollukayum cheythu.
ink pettant illaatha cancer marunnukalude liposomal formulationukal vikasippikkukayum 2005 ll taalon farmaceuticalsinu licenses nalkukayum cheythu; 2013 ll spectrum farmaceuticals taalon ettedukkukayum moonnu muun ink/tekmira uthppannangal vipaniyil athukayum tekmeeraykk royaltti srishtikkaan thudangukayum cheythu markibo (liposomal winkristeen), alokrest (liposomal vinorelbine), brackiva (liposomal topottekaan).
1998ll links therapeuticsil ninnu aarr. enn. aii saankethikavidyayumaayi bandhapetta boudhika swathavakaashathinum jeevanakkaarudeyum nirmmaana soukaryangaludeyum licensukalum ink nediyirunnu; eee saankethikavidyakalude koottam tekmirayude shradhaakendramaayi maari, thudakkathil vishalamaaya soochanakalkkaayi liposomaly encapsulated aarr. enn. aii marunnukal vikasippikkaan shramichu.
mattu kambanikalkku liposomal delivari saankethikavidya nalkunnathilum tekmira pravarthichu. 2007ll aalnilam farmaceuticalsumaayi oru licenses karar oppittu, athuvazhi alnilaminu swantham aarnai marunnukal vitharanam cheyyaan kazhiyum; aaa karar 2009ll oru nirmmaana kararayi vipuleekarichu.
vairal rogangalil shradha kendreekarikkaattha uthppannangalil bhooribhaagavum parajayappettu, 2011 ll aalnilaaminethire karar lamghichathinum vyapara rahasyangal moshtichathinum tekmiraykku 63 laksham dollar maathrame undaayirunnulloo. 2012ll techmiraykku 65 dasalaksham dollar termination phees nalkaan alnilaam sammathikkukayum aalnilaaminte ulppannamaaya pattisiran ulkkollunna kuranja naazhikakkallukalum royalttikalum upayogichu kambanikal oru puthiya licenses karar charcha cheyyukayum cheythathodeyaanu cases theerppaakkiyathu.
tekmira lokashradha aakarshikkukayum 2013 leeii vestt aafrikkan ebola vairas pakarchavyaadhiyude samayat athinte stokku naadakeeyamaayi uyarukayum cheythu, kaaranam ebola panikkulla marunnu candidate, tii. keey. emm-ebola. 140 dasalaksham us dollarinte prathirodha vakupp kararinu keezhil tekmira ithu vikasippikkukayayirunnu. 2015 januvariyil athinte stokku uyarnna nilayil vyapaaram nadathumbol, heppattaitis biyil shradha kendreekaricha oongoor biopharma enna kambani athu etteduthu.
2014 desember 19 nuu techmira kambaniyude director bordilekku muun bill & melinda gates foundeshan sii. eph. oo richard henrixine niyamikkunnathayi prakhyaapichu. executive vais presidentaayum cheef technical offeesaraayum iyaan mcclachlan pookumennu kambani oresamayam prakhyaapichu.
tii. keey. emm-ibolayude vikasanam 2015 juun pakuthiyode randaam ghatta pareekshanatthinide falapraapthiyude abhaavathil avasaanippichu.
adutha maasam, tekmira athinte peru arbutus biopharma ennu maattukayum heppattaitis bii chikilsikkunnathinulla marunnukalil shradha kendreekarikkumennu parayukayum cheythu.
2017 maarchil arbutus athinte liposome delivari saankethikavidyaykkaayi mattoru licensil oppuvachu, ithavana alaksan farmaceuticalsumaayi, oru mrna marunnu candidate vitharanam cheiyunnathinaayi. 2017 joolaiyil alaksan athinte coor compliment franchisic purathulla preclinical prograamukal nirthalaakkiyappol eee licenses avasaanippichu.
2019-ll, vittumaaraatha heppattaitis bii chikilsikkaan abb-506 upayogichu arbutus oru ghattam 1 klinikkal patanam aarambhichu. joolaiyil praadhamika vivarangal puratthirakkiya kambani rund rogikalkku acute heppattaitis baadhichathine thudarnnu octoberil vichaarana nirtthi. muun anweshana ejantumaarude vikasanam upekshichathinu sesham, 2021 leeii ilcyil avarude daatta mikacha reethiyil vottu cheythathinu sesham, randaam ghatta pareekshanangal thudaraan aduthide fda goo munnott vannathinaal ippol ebi-729 arbutusinu vazhiyorukkunnu. avarude adutha thalamurayile capsid inhibittaraaya abb-836 athinte onnaam ghatta pareekshanangalil mutentukalkkethire valia vaagdaanam kaanikkunnu.
2019 joolaiyil, alnilam farmaceuticals nilavil vilkkunna rna interference theraapyoottikkaaya oonpaatrooyude bhaaviyile aagola atavilppanayil royaltti palishayude oru bhagam 20 milyan dollarinu omezhsinu vilkkumennu arbutus biopharma prakhyaapichu.

