
shoonyamaaya sell

asthimajjaykkullil vikasikkukayum rogakaarikaleyum asaadhaarana koshangaleyum akramikkukayum cheiyunna valia granular lymphocytukalaanu nall cellukal. eee koshangalkk saadhaaranayaayi pakwathayulla bii cellukalilo tii cellukalilo kaanappedunnathupole resepterukal illa. pakwathayulla bii-cellukalilum tii-cellukalilum nall cellukale uparithala markerukalaayi tharamthirikkendathilla enna pothuvaaya savisheshathakalundu. vaasthavathil, sidi2 prakadippikkunnathil paraajayappedunna tii cellukalaanu nall cellukal. avaa valia granular lymphocytukalaanenkilum, avaa thaarathamyena cheruthum chromophobic koshangalumanu. chromophobic enna padam upayogikkumbol, oru prakasha microscopinu keezhil kaanumbol ennaanu ardhamaakkunnathu. eee koshangal cheruthaayi kaanapedunnu. lymphoid avayavangalil cheria alavil nall cellukal undengilum palappozhum noonn lymphoid tissuekalil kaanapedunnu. avayude cytoplaasathil ariyappedunna munkaala pityoottari hormonukal adangiyittillengilum, avayil hormon kashanagal, mungaamikal allengil jaivashaasthraparamaayi nishkriyamaaya padaarthangal thudangiya vividha gunangal adangiyirikkaavunna srava kanikakal adangiyirikkunnu. vishramakoshangalude praathinidhyamaayi, vividha kosha tharangalude mungamikalaayi allengil anjjaathamaaya kosha tharamaayi eee koshangale kaanunnu. 
oru jeeviyil kaanapedunna lymphocytukalude oru cheria anupaathamaan nall cellukal. virusukal polulla rogakaarikalude saannidhyathil avaa vegathil pravartthikkukayum emm. echu. sii niyanthrithamallaatha reethiyil vairal baadhichatho tumour koshangalo akramikkukayum cheiyunnu. mono nuclear koshangalude upajanasankhyayil kaalakramena shoonyakoshangalude ennam vardhichu. lymphocyteukal, monocytukal enniva polulla vrithaakruthiyilullathum ekavumaaya nucleusulla rakthakoshangalaan mono nuclear koshangal. rakthachamkramanathil ninnu verthirikkumbol avaye peripheral blud mono nuclear cellukal (pbmc) ennu vilikkunnu. ennirunnaalum, pokkil naadi, pleeha, asthi majja thudangiya sthalangalil iva kaanapedunnu. rogaprathirodha prathikaranatthinidayil shoonyakoshangal vardhikkunnathinaal, mattangal prayamaaya rogaprathirodha samvidaanavumaayi bandhapetta vaikalyangal moolamaanennu vishwasikkappedunnu, koodaathe aarogyamulla praayamaayavaril aarogyakaramaya rogaprathirodha samvidaanathinte praathinidhyamaayi ithu upayogikkaam, ithu athijeevanavumaayi bandhappettirikkunnu. 
lymphoid avayavangalil nall cellukal cheria ennathilaanengilum palappozhum noonn-lymphoid tissuekalil kaanapedunnu. vividha koshangalil lymphoid subsettukalude shekharanam niravadhi samvidaanangalude falamaanu. oru avayavathinullile aadya samvidaanam endothelial koshangalumaayum lymphocytukalumaayum chernnulla addition thanmaathrakalude prathipravartthanathiloode niyanthrikkappedunnath; randaamathethinu avayavathinte paarenkaimayiloode lymphocytukalude 'traansit' ennu peridunnu; oduvil, samvidaanathinte avasana ghattam rakthathilekko lymph naalangalilekko nerittu aanu. lymphocytukalkku prograam cheytha sell deth (apoptosis) allengil proliferation aarambhikkunnathin sajeevamaakkaavunnathinaal traansit ghattam nirnaayakamaan. ithu eathu avayavathilum eppol venamenkilum kaanapedunna lymphocytukalude ennam nalkunnu. 
lymphocyteukal jananathinu sheshamulla oru kaalayalavilekku phenotype pravarthanaparamaayum pakwata prapikkum. garbhaavasthayude 56 divasam muthal 8 aazhcha vare tii, bii lymphocytukalude vardhanavu undaakumbol nall lymphocyteukal kramanugathamaayi kurayum. oru yadhaartha velutha rakthaanuvine (monoclonal aantibodikal) cloning cheythukondu nirmmicha oru sell line upayogikkumbol, lymphocytukalude punachamkramanam nadakkunnathinu thelivukalundu, prathyekichu bronchoalviolar edangalil ninnu praadeshikamaayi vattikkunna lymph nodukalilekku kaanapedunna nall-sell subsettukalil.
chila arbudangalilum nall cellukal kandethiyittundu. pityoottari grandhiyil, nall sell adenomakal kandethiyittundu. pravarthanarahithamaaya eee tumorukalkkum adenomakalkkum ekadesham 20 sathamaanam varunna shoonyakoshangalundu. tumorous allatha adenohypophysilum nall cellukal thiricharinjittundu, ithu soochippikkunnathu nall sell adenomakal munpu nilaninnirunna benign nall cellukalil ninnaan uruthirinjathu ennaanu.

