
anabassin

maram pukayila ("nikottiyaana gloca") chediyilum saadhaarana pukayila chediyude ("nikottiyaana tabakkam") adutha bandhuvilum kaanapedunna pyridine, piperidine alcaloidaanu anabassin. ithu nikkottinte gadanaaparamaaya isomer raasaparamaayi nikkottinte samanamaaya oru isomerumaanu. athinte pradhana (charitraparamaaya) vyaavasaayika upayogam oru keedanashiniyaanu.
pukayila pukayilayil anabassin kurachumaathram adangiyittundu, ithu oru vyakthi pukayila pukayodu sanbarkkam pulartthunnathinte soochakamaayi upayogikkaam.
farmacology.
oru nicotinic asattailkolin risapttar agonistaanu anabassin. uyarnna alavil, ithu naadi vyaapanathinte oru depolarising block srishtikkunnu, ithu nicottin vishabaadhaykk samanamaaya lakshanangalkkum aathyanthikamayi asistol moolam maranathinum kaaranamakum. valia alavil ithu pannikalil terratogenic aanennu karuthappedunnu.
enanciomerine aashrayich elikalil anabasciente intravinus eldie50 11 milligram/kilogram muthal 16 milligram/kilogram vareyaanu.
analogukal.
bii. bhatti thudangiyavar. anaabaasinte chila uyarnna shakthiyulla sterik strained cyclic analogukal undaakki

