upapachayam shringhala

oru koshatthinte shaareerikavum jaiva rasaparavumaaya gunangal nirnnayikkunna upapachayam, shaareerika prakriyakalude poornnamaaya koottamaanu upapachayam. athupole, eee shringalakalil mettabolisatthinte raasapravarthanangal, metaboolik pathakal, eee prathikaranangale nayikkunna niyanthrana edapedalukal enniva ulppedunnu.
poornnamaaya genomukalude kramam anusarichu, bacteria muthal manushyan vareyulla pala jeevajaalangalilum biochemical prathikaranangalude shringhala punarnirmikkaan ippol kazhiyum. eee netvarkkukalil palathum oonlainil labhyamaanu
jeenukaludeyum genomukaludeyum (kegg), ecosice, biosike, mettattaigar ennivayude kyotto encyclopedia.
metabolism padikkunnathinum modeling cheiyunnathinumulla sakthamaaya upakaranangalaan metaboolik netvarkkukal.
upayogikkunnu.
rogikalaaya rogikalil comorbidity paattenukal kandethaan metaboolik netvarkkukal upayogikkaam. ponnatthadi, prameham thudangiya chila rogangal ore vyakthiyil oresamayam undakam, chilappol oru rogam mattoru rogathinu pradhana apakada gadakamaanu. rogathinte phenotypeukal saadhaaranayaayi koshathinu takarkkaano oru avashya substrate uthppaadippikkaano kazhiyaathathinte anantharafalamaanu. ennirunnaalum, oru prathikaranatthile oru ensime takaraar mattu thudarnnulla prathikaranangalude ozhukkukale baadhichekkaam. eee cascading efakttukal thudarnnulla prathikaranangalumayi bandhapetta upapachayam rogangale koottunnu, ithu comorbidity efakttukalkku kaaranamaakunnu. athinaal, parasparabandhithamaya prathikaranangal kaaranam rund vaikalyangal bandhappettirikkunno ennu nirnnayikkaan upapachayam roga shringalakal upayogikkaam.

