
aalkkaholukalude sulphonium adisthaanamaakkiyulla ookseekaranam aldehydeukalaayi maarunnu

aalkkaholukalude sulphonium adisthaanamaakkiyulla aldehydukalilekkulla ookseekaranangal oru praadhamika alcoholine anubandha aldehyda (anubandha kettonilekku dvitheeya alcohole) parivartthanam cheiyunna oru koottam jaiva prathikaranangale samgrahikkunnu. aalkkaholukalude aldehydukalilekkulla thiranjeduttha ooksideshan carboxylic aasidilekkulla amita ooksideshane marikadakkendathundu. intermediat alcoxysulphonium speesheesukaliloode (, udha.jii. samyuktham 6) ivide vishadamaayi. eee reethikalil bhooribhaagavum dimethylsulfoxide (dii. emm. ezz. oo) ooksidantaayi upayogikkukayum dimethylsulfide uthppaadippikkukayum cheiyunnathinaal, iva palappozhum dii. emm. ezz. oo-ooksideshanukalaayi churukkipparayunnu. ashayaparamaayi, oru alcoholil ninnum dii. emm. ezz. oyil ninnum aldehyde dimethylsulfide uthppaadippikkunnathin echu2oo neekkam cheiyunnathinu oru nirjjaleekarana ejantu aavasyamaanu, ithu oresamayam dii. emm. ezz. oo sajeevamaakkunna oru electrophylaanu. ithinu vipareethamaayi, dimethylsulfidil ninnu sulphonium intermediat uthppaadippikkunna reethikalkku oru nirjjaleekarana ejantu aavasyamilla. dimethyl selenoxide dimethyl selenide madhyasthatha vahikkunna ooksideshanukal adutha bandhamullavayaan.
bandhapetta reethikalumaayi thaarathamyam cheyyuka.
thaarathamyangalil, sulphonium adisthaanamaakkiyulla reethikal janapriyamaan, kaaranam prathikaranangal kaaryakshamamaan (uyarnna vilavu, thaarathamyappeduthumbol vegatha, amithamaya ooksideshan, kurachu paarshwapravartthanangal, punarnirmmikkavunna phalangal), prathikarana saahacharyangal mithamaan (kuranja thaapanila, sakthamaaya aasidukalo baseukalo illa), prathikaranangal pravartthanaparamaayi lalithamaanu (prathyeka upakaranangalo asaadhaaranavum koodaathe/allengil chelaveria reactorukaloo aavasyamilla, upolppannangal palappozhum eluppathil verthirikkappedunnu, ooksijanum eerppavum sahikkunnu), avaa saadhaaranayaayi uyarnna vishamulla prarambha vasthukkalum vishamaalinya nirmarjanavum ozhivaakkunnu. ennirunnaalum, laborattariyile niravadhi biruda rasatantra vidyaarthikalil eee prathikaranangal athra prachaarathililla, kaaranam saadhaarana upolppannamaaya dimethylsulfide, muttakal malinamaakkunnathine anusmarippikkunna sakthamaaya gandhamaan, ithinu nannayi vaayusanjaaramulla fume hood aavasyamaanu. adisthaanam adhikamaayi upayogikkunnathu, nirjjaleekarana ejantu kaikaaryam cheiyunnathu, laayakathinte parimithamaaya thiranjeduppu allengil uyarnna thapanilayil paarshwapravartthanangal enniva mattu poraaymakalil ulppedaam.jii. alcoholukalumaayi meedhailthiyomethail eetharukal roopappeduthunna reactive echu2sii = (ezz +)-ch3-speesheesukalilekku sulphonium intermediat punakrameekarikkukayo illaathaakkukayo cheyyuka. thathfalamaayi ithinartham prathikarana thaapanila vardhippikkunnathiloode ooksideshante pravartthanam ishtaanusaranam tyoon cheyyaan kazhiyilla ennaanu.jii. oru nishkriya madyathinte ooksideshan nirbandhikkuka.
eee sulphonium adisthaanamaakkiyulla reethikalkku saadhaarana badalukal ooksideshanukalaanu. 
vibhagangal.
sulphonium ooksideshanukale rund grouppukalaayi tharamthirikkaam aadyakaalangalil kandethiya reethikal alkail tosailettukal (konblam ooksideshan) allengil alkail chloroformateukal (aalkkaholukalude fosjeenumaayulla prathikaranatthil ninnu barton-konblam) polulla sajeeva aalkkaholukale aasrayikkunnu, avaa dii. emm. ezz. oo upayogichu chikilsikkumbol electrophylukalaayi pravartthikkukayum ooksijan adangiya leaving groupine swathanthramaakkukayum cheiyunnu (udha.jii. ). ennirunnaalum, madyam pree-aaktivett cheiyunnathinulla adhika ghattavum chilappol nucleophilic sthaanachalanathinulla kadinamaaya prathikarana saahacharyangalum soukaryapradamallennu thelinju. athinaal, sajeevamaaya sulfoxideukal uthppaadippikkunna reethikal pinneedu vikasippicheduthu. chuvade chithreekarichirikkunnathu swern ooksideshan 4-ll ulppaadippikkunna sajeevamaaya sulfoxide, secondary alcohol 5-maayi prathipravartthichu alcoxysalphonium speeshees 6 roopappedunnu. eee sajeevamaaya sulfoxideukal oru alcohol upayogichu chikilsikkumbol electrophylukalaayi prathipravartthikkukayum oresamayam srishtikkappedunna alcoxysalphonium speesheesinu () ethir ayanayi pravarthichekkaavunna oru leaving groupine puratthaakkukayum cheiyunnu. deprotonationil-saadhaaranayaayi triathilaamain polulla mithamaaya aditharayude sahaayathode-alcoxysulphonium inam vighadichu aldehyde, dimethylsulfide enniva nalkunnu. randaamathe shekharathil janapriya ooksideshanukal adangiyirikkunnu 
koodaathe aalbrait-goldman, aalbrait-onodera (dmso/pii2oo5), tfaa/dmso (swern), eme2ezz/cl2 ennivayum ulppedunnu. aduthide, dmsoil ninnu sajeevamaaya sulfoxide uthppaadippikkunnathin eso2eph2 nirddeshikkappettittund.

