
ashraf brick

israelile technian instittyoott oof teknolajiyil kemistry skoolichu faakkalttiyile phul professoraanu ashraf brick (jananam juun 29,1973).
proteinukalude raasasamsleshanathinaayi poost-translation parishkkaranangal (pii. tii. emm. ezz) upayogichu avaye nannayi padikkaan anuvadikkunna alavil synthetic reethikal vikasippikkunnathil addehathinte laborattari vaidagdhyamundu. vividha rogangalil earppettirikkunna ensaimukaleyum (dubicvitinusukal polullava) proteinukaleyum swaadheenikkunnathinaayi cheria thanmathrakal, pepttaidukal, peptidometics ennivaye adisthaanamaakki puthiya modulettarukal brick group vikasippikkunnu. eee upakaranangalude sahaayathode, thanmaathrakalum jaiva samvidaanangalum aarogyathe engane baadhikkunnuvenn manasilakkaan kazhiyum.
aadyakaala jeevithavum vidyaabhyaasavum.
patthu makkalil oralaaya brick vadakkan israelile abu snaanilaan janichathum valarnnathum.
negevile benn-guriyon sarvakalashaalayil ninnu rasathanthrathil birudaananthara birudavum technitionil ninnu rasathanthrathil birudaananthara birudavum nedi. professor chii-hyui vonginte maarganirdeshaprakaaram technicianteyum scrips research instittyoottinteyum samyuktha kozhsil ninnu proteinukalude raasa samanvayathekkurichulla gaveshanathil shradha kendreekarichukondu addeham doctoral birudathinaayi padichu.
professor ehud keynan (technian), professor philipp dosson (scrips research instittyoott) ennivarude melnottatthil "polypeptide scarfoldukale adisthaanamaakkiyulla puthiya kaattalatik proteinukalude roopakalppanayum samanvayavum" enna prabandham brick rachichu.
2004ll muthirnna gaveshakanaayi sthaanakkayattam labhichu. addeham glycoproteinukalude synthesis vikasippichu. koodaathe, echuaivi protees polulla vividha ensaimukalude inhibittarukal kandethunnathumaayi bandhapetta padhathikalil brick earppettirunnu.
currier.
2007ll brick negevile benn guriyon sarvakalaashaalayile rasatantra vibhaagathil chernnu. 2011ll associate professorayum 2012ll phul professorayum sthaanakkayattam labhichu. 2014-ll brick technician instittyoott oof teknolajiyilekku maari, avide addeham jordan, airin tarq cheyar vahikkunnu. 
shaasthram, prakrithi rasathanthram, prakrithi kemikkal biology, prakrithi protocolukal, jenal oof dhii american kemikkal sosaitti, aanjvaandatt kemi, kemikkal sosaitti avalokanangal, kemikkal sayans thudangi 120 ladhikam prasidheekaranangal brick rachichittundu. sell kemikkal biology, kembiyokem, oorgaanik, biomolecular kemistry ennivayulppede niravadhi aanukaalikangalude upadeshaka, editting bordukalil brick amgamaanu. 6 pettantukalum addeham rajisttar cheythittundu.
aduthide addehathinu iii. aarr. sii advanced graant nalkia europian kammeeshante horisoon 2020 prograam ulppede niravadhi foundeshanukalaanu brikkinte grouppinte gaveshana shramangalkk bajatt thayyarakkunnathu.
gaveshanam.
proteinukalude poost translation parishkkaranam protein ghadana, pravartthanam, sthiratha, sub sellular localisation ennivaye baadikkukayum eee prakriya aarogyathinum rogathinum nirnayakamaakkukayum cheiyunnu. ennirunnaalum, parambaraagatha biochemical, molecular biology sameepanangaliloode labhikkuna ekeekrithamaayi parishkkaricha proteinukalude abhavam eee parishkkaranangalude phalangal tanmatra thalatthil manassilaakkunnath thadassappeduthunnu. mathramalla, atharam sankeernamaaya bayokonjugettukal pravarthanakshamamaaya alavil thayyarakkunnathu valare aavasyamullathaanu. raasa, ardhasinthattik sameepanagal prayogikkunna protein rasathanthrathile sameepakaala munnettangal eee velluvilikale marikadakkaan kooduthal prayojanakaramaanu. biochemical, biophysical, functional vishakalanangalkkayi saitt-prathyekamaayi parishkkaricha proteinukal thayyaaraakkunnathin brick laab puthiya synthetic reethikal vikasippichukondirikku.
ubiquitin signalinginekkurichula vishadamaaya padanangalkku aavashyamaaya ubiquitin adisthaanamaakkiyulla konjugettukal thayyarakkunnathinulla puthiya reethikal avishkarikkunnathil lokanethaakkalil oraalaan brick group. 76 amino assid ubiquitin protein allengil oru polyubikvittin shringhala oru protein taargettumaayi bandhippichirikkunna sellular prakriyayaan sarvvyaapanam, ithu protein degradation, transcription, dna naashanashta prathikaranam thudangiya vividha jaiva prakriyakale badhikkunnu. neurological disordezhs, pakarchavyaadhikal, cancer thudangiya vividha rogangalil sarvvyaapanam oru pradhana punk vahikkunnathil athishayikkanilla. parambaraagatha molecular biology ensaimatik sameepanangalum upayogichu ubiquitin konjugettukal ulppaadippikkunnathile velluvilikal neridumbol, brick laab uyarnna alavilulla ekathaanavum shudhavumaaya ubiquitin konjugettukal thayyarakkunnathinaayi niravadhi puthiya raasa reethikal vikasippicheduthittundu, avaa ubiquitin signalinginte samvidaanangalil velicham veeshukayum eee prakriyakalil ulppedunna ensaimukalkkaayi puthiya modulettarukal kandethunnathu praapthamaakkukayum cheythu.

