annexin eiii6

manushyaril "ansa 6" jeane encode cheiyunna oru proteinaan annexin eiii 6.
pravartthanam.
kaalsyam ashrita membran, phospholipid binding proteinukal ennivayude oru kudumbatthil pedunnathaanu annexin vii. avayude pravartthanangal ippozhum vyakthamaayi nirvachikkappettillettil, annexin kudumbatthile niravadhi amgangal exocytotic, endocytotic paathakaliloode membranumaayi bandhapetta sambhavangalil ulppettittund. ekadesham 60 keey. bii. pii neelamulla annexin vii. aii. jeenil 26 exonukalundu. ithu ekadesham 68 keey. dii. eiii. yude oru proteine encode cheiyunnu, athil ettu 68-amino assid aavarthanangal adangiyirikkunnu, variable neelangalude sequenceukal bandhippichu verthirikkunnu. ithu manushya anexinukal I, II seekwansukalumaayi valare saamyamullathaan, avayil oronninum atharam naalu aavarthanangal adangiyirikkunnu. annexin vi-yude exon 21 marimari splies cheythirikkunnu, ithu ezhaamathe aavarthanathinte thudakkathil 6-amino assid ulppeduthunnathiloode vyathyaasappedunna rund isophomukalkku kaaranamaakunnu. exocytosis samayat epithelia sravikkunnathil endosome aggregation vesicle fusion madhyasthamaakkunnathil annexin vii ulppettittund.
maathrukaa jeevikal.
ansa 6 fangshanekkurichulla padanatthil maathrukaa jeevikal upayogichittundu. velkkam trastt sanger instittyoottil thaalpparyamulla shaasthranjarkku rogathinte mruga maathrkakal srishtikkunnathinum vitharanam cheiyunnathinumulla uyarnna-throoput mutagenesis projectaaya anthaaraashtra nokkautt mouse kansorshyam prograaminte bhaagamaayi bhaagamaayi (ucom) ibluts" ennu vilikkunna oru vyavasthaapitha nokkautt mouse line srishtichu.
illaathaakkalinte phalangal nirnnayikkaan aann, penn mrugangal oru staanderd phenotypic screenin vidheyamaayi. mutent elikalil irupathiyaaru parisodhanakal nadathukayum oru pradhana asaadhaaranatha nireekshikkukayum cheythu penn homocygus mutent mrugangalkku "citrobactor" anubaadhaykkulla saadhyatha vardhichu.
ashayavinimayam.
ansa 6 raas pii 21 protein aaktivettar 1-maayi edapedunnathaayi theliyikkappettittund.

