vrishanangal prakadippichu 15

manushyaril tex 15 jeane encode cheiyunna oru proteinaan 15 ennu vrishanangal prakadippikkunnu.
tex 15" jeane vrishana-nirddishta aavishkaaram pradarshippikkunnu, chromosome 8 lekkulla maappukal, naalu exonukal adangiyirikkunnu, koodaathe 2789-amino assid proteine encode cheiyunnu. tex 15" jeane miyosisile pradhana dna naashanashta prathikarana gadakathe encode cheiyunnu. 
mrugangalekkurichulla padanangal.
elikalil, "tex 15" jeeninte orthologue thadassappedunnathu vrishanathinte valuppathil ganyamaaya kurravinum purushanmaaril meotic arasttinu kaaranamaayi. chromosome synapsis, myotic recombination, dna double-strand break repire ennivaykku elikalil tex 15 aavasyamaanu. koodaathe, dna double-strand brekkukalude cytukalilekku recompination proteinukalude (raadu 51, dmc 1) loading tex 15 niyanthrikkunnu, athinte abhavam myotic recompination paraajayappedaan kaaranamaakunnu. 
klinikkal praadhaanyam.
tex 15" jeenil oru mutation purusha vandhyathayumaayum meotic pakwata thadasavumaayum bandhappettirikkunnave kandethi.
tex 15-nte vettimatta vakabhedangalum sthanaarbudathinulla saadhyathayulla gadakangalaanu.

