
marcello jacobs-lorena

oru brazilian-american molecular entamolajistaanu marcello jacobs-lorena. johns hopkins bloomberg school oof public healthile molecular microbiology aandu immunology vibhaagathil professoraanu addeham. 2002ll addehathinte samgham kothukukalil oru parishkaricha jeane nirachu, angane avayude hridayam plaasmodiyathe kollunna oru padaartham uthpaadippikkunnu.
aadyakaala jeevithavum vidyaabhyaasavum.
jacobs-lorena saavo poulo sarvakalashaalayil ninnu baachilar oof arts birudavum osakka sarvakalashaalayil ninnu birudaananthara birudavum poortthiyaakki phdkaayi vadakke amerikkayilekku pooyi.dii. masaachyusets instittyoott oof teknolajiyil.
currier.
piechdiyethudarnnu, 1977-ll cases vestten reserve yooniversittiyile (sii. dablyu. aarr. yuu) janithakashaasthra vibhaagathile faakkalttiyil jacobs-lorena chernnu. faakkalttiyile amgamenna nilayil, kothukukalude manass plaasmodiyathe kollunna oru padaartham ulppaadippikkunnathinu parishkkaricha jeane nirachu malaria chikilsikkunnathil addeham oru supradhana kandethal nadatthi. kothukukalude kudalile resepterukaleyum umineer grandhikaleyum thadayunnathinaayi avar pepttaidukale encode cheythu, angane plasmodiathinu praanikalil aavarthikkaan kazhiyilla, kothukukal kadikkumbol manushyare badhikkunnu. eee kandethalinethudarnnu, malaria gaveshanathinaayi anjjaathamaaya sambhavana labhichathinaal jacobs-lorena johns hopkins sarvakalaashaalayilekk (juu) niyamichu. pinneedu addeham molecular microbiology aandu immunology vakuppilum bloomberg school oof public healthile (jhmri) malaria research instittyoottilum professoraayi.
jamriyil chernnappol, jacobs-lorena sahapravarthakanaaya eeppan jii. plasmodium parannabhojiyodu prathirodhasheshiyulla oru transgenic kothukine ebraham vikasippikkaan thudangi. spran6 jeane sthiramaayi sajeevamaakumbol, manushyarilekkulla malaria pakarunnathine thadassappeduthaan oru kothukinu kazhiyum. eee mekhalayile addehathinte thudarchayaaya gaveshanam transgenic kothukukal kooduthal kaalam jeevikkunnuvennum avayude parishkkarikkappedaathu athiraalikalekkaal kooduthal muttakal uthpaadippikkunnuvennum nirnnayikkaan addehathe prerippichu. transgenic kothukukal kooduthal santhathikal janippikkukayum kooduthal kaalam jeevikkukayum cheiyunnidatholam kaalam malaria vahikkunna kothukukalkk pakaram malaria prakrithiyil avatharippikkaamenn eee kandethalukal soochippikkunnu. pinneedu 2007-ll, malaria undaakkunna parannabhoji kothukinte kudalumaayi bandhippikkaan anuvadikkunna kothukukalile panchasaara jacobs-lorena sahapravarthakarum thiricharinju. kothukile panchasaarayude alavu kurachukondu, kothukile 95 sathamaanam paraannabhojikalum kudalilekku cherunnathu thadayaan kazhiyumennu addehathinte gaveshana samgham nirnnayichu. janithakamattam varuthiya kothukukal vikasippikkunnathinulla addehathinte sramangal gaveshanam, bisinesses allengil nayaroopeekaranam ennivayile nettangal mikacha saankethika neethrthwam prakadamaakkunna oru gaveshakanenna nilayil "scientific american" enna nilayil addehathinu amgeekaaram nalki.
2009 muthal 2012 vare, maleria illaathaakkaan sahaayikkunnathin jacobs-lorena kothukukalil niravadhi puthiya kandethalukal nadatthi. 2009-ll, anophilis kothukile umineer grandhikale badhikkaan plaasmodiyathe prapthamaakkunna tanmatra gadakangal aadyamaayi thiricharinjathu addehathinte gaveshana samghamaanu. pinneedu, onpathu thalamurakalk sesham avarude janithakamaayi nirmmicha kothukukal maattamillaatha, malaria sauhruda kothukukale athijeevichathaayi addeham prakhyaapichu. keedaanukkalude rogaanukkalude jeevashasthram, prathyekichu malaria paraannabhojikal/kothukukal thammilulla edapedal, kothukukalude rogaanukkalude kazhivile janithaka maattam ennivaykku vishishta sambhavanakal nalkiyathinu" jacobs-lorena pinneedu american association phoor dhii advaansment oof sayansinte fello aayi thiranjedukkappettu."2012 ll, addehathinte gaveshana samgham kothukukalude hridayathil sahavarthithvathode jeevikkunna bakteeriyakalil shradha kendreekarikkaan thudangi, avaye paraannabhojikalude vikasanathe thadassappeduthunna samyukthangal uthpaadippikkunnathinaayi parishkkarikkuka enna lakshyathode. avarude anophilis kothukukalude track thudaraan, jacobs-lorena mattu shaasthranjarum jambiayile maachayil oru soukaryam nirmmichu. eee soukaryam puthiya keedanashinikal, akarshakavasthukkal, maleria prathirodhikkaan janithakamaayi parishkkaricha kothukukal enniva kooduthal krithyamaayi vilayiruthaan avare anuvadichu.
2017-ll, kothukukalude ennathil serasia bacteria strain (eiii. ezz. 1) phalapradamaayi avatharippikkan jacobs-lorena thante sahapravarthakanaaya sibavo vaamgine sahayichu. aanti-plasmodium ifakttar proteinukalude sravathinaayi janithakamaayi roopakalppana cheythathaanu aas 1, koodaathe recombinent strainukal kothukukalil plasmodium faalsipaaratthinte vikaasathe thadayunnu. eee kandethalinethudarnnu, jacobs-lorena gaveshana samgham kothukukalude genomukalilekku nerittu aanti malarial jeenukal cherthu cross speesheesukal chaadunnathu thadayaan sramikkaan thudangi. pothujanaarogyathino klinikkal swaadheenathino kaaryamaaya saadhyathakalulla oru pradhana shaasthreeya sambhaavanaykk 2021 ll jacobs-lorenaykku kandethalinum naveekaranathinumulla shikani/ell hibri sammanam labhichu.

