
sumo ensimeukal

sumo ensaimatik cascade sumoyleshante chalanathmakamaaya poost translation modification prakriya uthejippikkunnu (i.iii. mattu proteinukalilekkulla sumo protein kaimaattam). moonnu vyathirikthamaya ensaimatik ghattangaliloode (valathuvashathulla chithram kaanuka) athinte substrateukalumaayi samyojippichirikkunna oru ubiquitin polulla kudumba amgamaanu cheria yubikvittinumaayi bandhapetta modifier, sumo-1: sajeevamaakkal, iii 1 ensime ulppedunna (seyy 1/seyy 2); iii 2 ensime (yubi 2 aii) ulppedunna samyojanam; iii 2, iii 3 protein ligasukalude sahakaranathiloode substrate parishkkaranam.
vividha sellular prakriyakalil pankedukkunna noorukanakkinu proteinukale sumo pathway parishkkarikkunnu. pathiladhikam valia thothilulla padanangalil thiricharinja dhaaraalam sumoilated proteinukal theliyikkunna, vaividhyamaarnna sellular sambhavangale niyanthrikkunna ettavum kooduthal padicha ubiquitin polulla paathayaan sumo pathway.

