
trimethylsililaserine

trimethylsililiserine enna soothravaakyamulla oorgaanoosilikkan samyukthamaanu. tms asattileen" ennum vilikkappedunna niramillaatha draavakam jaiva samanvayathil "echsi2−" nte uravidamaayi upayogikkunnu.
upayogikkuka.
sonogashira couplingukalil asattileeninu thulyamaayi trimethylsililiserine upayogikkunnu. asattileeninu vipareethamaayi eee samrakshitha alkine upayogikkunnathu kooduthal coupling prathikaranangal thadayunnu. trimethylsilil groupine tibaf allengil dibu upayogichu verthirikkaam, onnukil vevvere allengil oru-paathram sonogashira prathikaranatthinte bhaagamaayi finailaattileen derivateevukal roopappeduthaam. 2-methylbut-3-inn-2-ool aanu chelavu kuranja oru badal riyejant, ithu alcainylation sesham bays upayogichu samrakshikkappedunnu.
trimethylsililaserine vaanijyaparamaayi labhyamaan. mattu silail samyukthangalkk samanamaaya reethiyil ithu thayyarakkam grignard reyejantinoppam asattileen deprotenation, thudarnnu trimethylsilil chloridemaayulla prathikaranam.
1, 4-biss (trimethylsilil) beauta-1,3-dainin enna 1,3-beautadininte samrakshitha roopathinte munnodiyaanu trimethylsililiserine.
charithram.
1959ll heins gunder viyeyaan trimethylsililaserine aadyamaayi samanvayippichathu. addeham diethyl eetharile finillithiyavumaayi prathipravartthichu chloro (trimethylsilil) asattileen kuraykkukayum thudarnnulla jalavishleshanavumaayi munnott pookukayum cheythu.

