synthetic janithaka shreni

synthetic janithaka shreni vishakalanam (ezz. jii. eiii) synthetic maarakavum synthetic siik janithaka edapedalukalum (ezz. ezz. ell) paryavekshanam cheiyunnathinulla uyarnna-throoput saankethikathayaanu. recombinent janithaka saankethikavidyakal, inacheral, thiranjedukkal gattangal ennivayude samyojanam upayogichu eratta myoottantukalude chittayaya nirmmaanathinu ezz. jii. eiii anuvadikkunnu. ezz. jii. eiii reethishaasthram upayogichu oru kwari jeane deletion mutent oru muzhuvan genome deletion settilekku kadakkaan kazhiyum, ithu eathenkilum ezz. ezz. ell edapedalukal thirichariyunnu, ithu kwari jeeninteyum athu samvadikkunna jeenukaludeyum pravarthanaparamaaya vivarangal nalkunnu. 130 kwayari jeenukal yeesttile ~ 5000 praayogikamaaya illaathaakkal myoottantukalude koottatthilekku kadakkunna ezz. jii. eyude oru valia thothilulla prayogam ~ 1000 jeenukalum ~ 4000 ezz. ezz. ell edapedalukalum adangiya oru janithaka shringhala velippeduthi. eee padanatthinte phalangal kaanikkunnath samanamaaya pravartthanamulla jeenukal parasparam edapazhakunna pravanatha kaanikkunnu, janithaka edapedalukalude samanamaaya paattenukalulla jeenukal palappozhum ore paathayilo sankeernathayilo pravartthikkunna uthppannangale encode cheiyunnu. synthetic janithaka shreni vishakalanam thudakkathil model oorganaiseshanukal upayogichaanu vikasippichath. serivisiye ". athinusesham eee reethi 30 sathamaanam varunnavarkkayi vipuleekarichu. serivisiya "genome. ezz. jii. eiii vishakalanam anuvadikkunnathinaayi reethishaasthram vikasippicheduthittundu.pombe ", iii. koolii ".
pashchaathalam.
synthetic janithaka shreni vishakalanam aadyam vikasippichath tong muthalaayavaraan. 2001 ll ithu vaividhyamaarnna biomedical mekhalakalil pravartthikkunna niravadhi grouppukal upayogichu. yeest genome illaathaakkal padhathi srishticha muzhuvan genome yeest noock-outtu settum ezz. jii. eiii upayogikkunnu.
nadapadikramam.
saadhaarana saandrathayil (96,384,768,1536) petriplettukalile koolani arekal upayogichaanu synthetic janithaka shreni vishakalanam saadhaaranayaayi nadathunnathu. s-ll oru ezz. jii. eiii vishakalanam nadatthaan.serivisiya, "kwari jeane illaathaakkal kramanugathamaayi oru illaathaakkal mutent shreni (dma) upayogichu cross cheiyunnu, ithil yeest genome (nilavil 4786 strainukal) yude ellah praayogika nokkautt oorfukalum adangiyirikkunnu. thathfalamaayundaakunna diployidukal pinneedu naitrajan kuranja oru maadhyamathilekku maattunnathiloode chitharikkidakkunnu. eratta mutentukalkkaayi thiranjedukkunnathinaayi haployed santhathikale selection platingukaliloodeyum inkubeshanukaliloodeyum oru parambarayiloode athikkunnu. eratta mutentukal drishyaparamaayi ezz. ezz. ell edapedalukalkkaayi allengil thathfalamaayundaakunna kolanikalude valuppam vilayiruthikkond imaging software upayogichu parishodhikkunnu.
robotics.
ezz. jii. eiii vishakalanathile krithyamaaya replication gattangal kaaranam, koolani krithrimathvangal nadatthaan robottukal vyaapakamaayi upayogikkunnu. ezz. jii. eiii vishakalanathinayi prathyekamaayi roopakalppana cheythirikkunna chila samvidaanangalundu, ithu oru kwayari jeane vishakalanam cheyyaanulla samayam valareyadhikam kuraykkunnu. saadhaaranayaayi ivaykku plettukalilekkum avayil ninnum koshangal kaimaran upayogikkunna pinnukalude oru parambarayundu, oru sisttam alakkal cycleukal illaathaakkaan dispossible paadukal upayogikkunnu. plettukalude chithrangalil ninnu koolani valuppangal vishakalanam cheyyaan computer prograamukal upayogikkaam, angane ezz. jii. eiii scoring kemikkal-janithaka profile automate cheiyunnu.
oru yeest uyarnna ulladakkamulla genome-wide janithaka screening systethinaayulla gattangal (sga-rooad mapp).
aarr pradhana gadakangalunda

