
tii. bii. sii1dii24

manushyaril tbc1dii24 jeane encode cheiyunna oru proteinaan tbc1 domaine famili, memper 24.
pravartthanam.
eee jeane oru samrakshitha domainullah oru proteine encode cheiyunnu, ithine gbc domaine ennu vilikkunnu, ithu jidipesukalumaayi samvadikkunna proteinukalude savisheshathayaanu. oru prathyeka groupile jidipesukalude jidipes-activating proteinukalaayi tbc domaine proteinukal pravarthichekkaam, membran trafficing niyanthrikkunnathil ulppedunna raab (thalachorile raasumaayi bandhapetta proteinukal) cheria jidipesukal. eee jeenil undaakunna mutationukal familial infanttail myoclonic apasmaravumaayi bandhappettirikkunnu. badal spliesing onniladhikam traanskript vakabhedangalil kalaashikkunnu.
tii. bii. sii. 1dii24-leeii mutationukal paarambaryamaayi kelvikkuravinu kaaranamaakunnu.

