
estradiol dipropionate

agopholin, dii-ovosilin, projinon dipi ennee brand namangalil vilkkunna estradiol dipropionate (eiii. dii. pii), aarthavavirama lakshanangalkkum sthreekalil eestrajan alavu kurayunnathinum gynaecological disordezhs chikilsaykkum hormon therappiyil upayogikkunna oru eestrajan marunnaan. transgender sthreekalkkulla hormon therapy feminisise cheiyunnathinum purushanmaaril prostettu cancer chikilsaykkum ithu upayogichittundu. munkaalangalil vyaapakamaayi upayogichirunnuvenkilum, estradiol dipropionate pradhaanamaayum nirthalaakkappedukayum innu kooduthalum labhyamallathaavukayum cheythu. jappan, macedonia, austreliya ennividangalil maathrame ithu ippozhum upayogathilulloo. aazhchayil onno rando thavana muthal aazhchayil onnara muthal randaazhcha vare edavelakalil peshikalilekku kuthivaykkalaanu estradiol dipropionate nalkunnathu.
stanarbudam, stanarbudam, ookkaanam, thalavedana, draavakam nilanirtthal enniva estradiol dipropionettinte paarshwafalangalil ulppedunnu. eastradiol dipropionate oru eestrajan aanu, athinaal eestrajan resepterinte oru agonistaanu, ithu eastradiol polulla eestrajanukalude jaiva lakshyamaanu. ithu oru eestrajan esttarum shareerathile estraadiyolinte oru prodragumaanu. ekkaaranathaal, ithu eestrajante swaabhaavikavum jaivavaividyaparavumaaya roopamaayi kanakkaakkappedunnu.
1937ll pettant nediya estradiol dipropionate 1940 aayappozhekkum vaidyashaasthraparamaaya upayogathinaayi avatharippikkappettu. upayogichirunna aadyakaala estradiol esttarukalil onnaanith. estradiol benzoatinoppam, estradiol dipropionate athinte avatharanathinu sesham niravadhi varshangalil estraadiyolinte ettavum vyaapakamaayi upayogichirunna esttarukalil onnaayirunnu.
medical upayogangal.
estradiol dipropionettinte vaidyashaasthraparamaaya upayogangal estradiolinteyum mattu eestrajanukaludeyum upayogathinu thulyamaanu. hormon therappiyil hoott flashukalum yoniyile ksheenam polulla aarthavavirama lakshanangalude chikilsaykkum hypogenonism, hypogonadisamo mattu kaaranangalo moolam kaalathamasam varuthiya praayapoorthiyaakal ennivayude chikilsaykkum estradiol dipropionate upayogikkunnu. transgender sthreekalkkulla feminising hormon therapyilum ithu upayogikkunnu. hormon therapic purame, aarthava vaikalyangal, pravarthanarahithamaaya garbhashaya rakthasraavangal, stanarbudam thudangiya gynaecological vaikalyangalude chikilsayil estradiol dipropionate upayogikkunnu. koodaathe, purushanmaaril prostettu kaansarinte palliative chikilsayil uyarnna alavil eestrajan therapy oru roopamaayi ithu upayogikkunnu.
estradiol dipropionate saadhaaranayaayi aazhchayil onno rando thavana intramuscular kuthivayppiloode 1 muthal 5 milligram vare alavil upayogikkunnu. thudakkathil rund muthal moonnu kuthivayppukalkku 1 muthal 5 milligram vareyum 10 muthal 14 divasathilorikkal paripaalanathinaayi 1 muthal 2.5 milligram vareyum aarthavavirama lakshanangalude chikilsayilum aazhchayil orikkal 2.5 muthal 5 milligram vare alavil hypo eastrajanism, kaalathamasam varuthiya praayapoorthiyaakal ennivayude chikilsayilum ithu upayogikkunnu. transgender sthreekalkkulla feminising hormon therapy oru gadakamenna nilayil, aazhchayil orikkal 2 muthal 10 milligram vareyo allengil 2 aazhchayil orikkal 5 muthal 20 milligram vareyo estradiol dipropionate upayogikkunnu. prostettu kaansarinte chikilsayil, aazhchayil orikkal 5 milligram alavil estradiol dipropionate upayogichittundu.
labhyamaya foomukal.
0. 1, 0. 2, 0. 5, 1, 2.5,5 milligram/millie saandrathayil kuppikalaayum aampyoolukalaayum nalkunna intramuscular kuthivayppinulla enna parihaaramaayi munbu estradiol dipropionate labhyamaayirunnu. eee formulationukalil bhooribhaagavum labhyamallathathinaal marunnu pradhaanamaayum nirthalaakki. jappaanile iii. pii. hormon dippo (teacocu sokki farmaceutical kambani) enna brand naamatthil 50 milligram/millie hydroxy projastaron caproyettinoppam 1 milligram/millie saandrathayil estradiol dipropionate labhyamaan.
ethirvashangal.
eestrajanukalude virudhachihnangalil kattapidikkunna prasnangal, hridayasambandhamaaya rogangal, karal rogam, stanarbudam, endometrial cancer thudangiya chila hormon sensitiivu cancerukal enniva ulppedunnu.
paarshwafalangal.
estradiol dipropionettinte paarshwafalangal estraadiyolinte paarshwafalangalkku thulyamaanu. atharam paarshwafalangalude udaaharanangalil sthanangalkk aardrathayum veekkavum, ookkaanam, veekkam, veekkam, thalavedana, melasma enniva ulppedunnu.
amithamaya alavil.
ookkaanam, chharddi, veekkam, bharam vardhikkal, vellam nilanirtthal, sthanangalkk aardrata, yoniyil ninnulla discharge, kanatha kaalukal, call vedana enniva eestrajan amithamaayi kazhikkunnathinte lakshanangalil ulppedaam. eestrajan alavu kuraykkunnathiloode eee paarshwafalangal kuraykkaan kazhiyum.
ashayavinimayam.
cytochrome pii450-nte inhibittarukalum indusserukalum estraadiyolinte mettabolisatheyum estraadiyolinte alavu vipuleekarikkunnathiloode swaadheenichekkaam.
farmacology.
pharmacodynamics.
estradiol dipropionate oru estradiol esttar allengil estraadiyolinte oru prodrug aanu. athinaal, ithu oru eestrajan allengil eestrajan resepterukalude agonistaanu. sii3, sii17bitta propionate esttarukalude saannidhyam kaaranam estradiolinekkaal 41 sathamaanam kooduthal tanmatra bhaaramullathaan estradiol dipropionate. estradiol dipropionate estraadiyolinte oru prodrug aayathinal, ithu eestrajante swaabhaavikavum jaivavaividyaparavumaaya roopamaayi kanakkaakkappedunnu.
pharmacokinetics.
estradiol bensoyettumaayi thaarathamyappeduthumbol, estradiol depropionate mechappeduthukayum deerghakaala phalangal nalkukayum cheiyunnu. estradiol bensoyettinte pravartthana dairkhyam 2 muthal 3 divasam vareyum estradiol dipropionettinte dairkhyam 1 muthal 2 aazhcha vareyumaanu. ennirunnaalum, puthiya estradiol estarukalkku estradiol benzoate allengil estradiol dipropionettinekkaal kooduthal dairkhyamundu; estradiol vaalarettinte dairkhyam 1 muthal 3 aazhcha vareyum estradiol cypionettinte dairkhyam 3 muthal 4 aazhcha vareyum aanennu parayappedunnu. 5 milligram estradiol dipropionettinte orotta intramuscular kuthivayppinu ekadesham 5 muthal 8 divasam vare dairkhyamundu.
15 praayapoorthiyaaya penkuttikalil (50 kilogram (110-poundu) penkuttikku ekadesham 1 milligram) ennayil 50 microgram/kilogram estradiol dipropionate enna orotta intramuscular kuthivayppu 1.5 divasathinu sesham ekadesham 215 piji/millie enna uyarnna estradiol alavu uthpaadippikkunnathaayi kandethi. 4 divasathinu sesham estraadiyolinte alavu ekadesham 90 pii. jii/millie aayi kuranju.
rasathanthram.
estradiol 3,17β-depropionate ennum ariyappedunna estradiol depropionate, oru synthetic estraine steroid estradiolil ninnu uruthirinjathumaanu. ithu oru eestrajan estaraanu; prathyekichum, ithu estraadiyolinte c3,17β dipropionate estaraanu.
estradiol dipropionettinte pareekshanathmaka okdanol/vaattar partition coffificient (logue) 4.9 aanu.
charithram.
1937-ll estradiol dipropionate aadyamaayi samanvayippikkukayum pettant nedukayum cheythu. 1939-oode klinikkal padanangalil ithu vilayiruthukayum athe varsham thanne "dii-ovosilin" enna brand naamatthil intramuscular kuthivayppiloode upayogikkunnathinulla enna parihaaramaayi siba avatharippikkukayum cheythu. siba upayogichulla "ovosaiklin pii", shering upayogichulla "projinon dipi", roock-organon upayogichulla "dimenformon dipropionate" thudangiya mattu formulationukalum 1940 kalude thudakkathil vipananam cheyyappettu. pinneedu 1940kalil "dii-ovosilin" enna brand namam siba "ovosilin dipropionate" ennu maatti. 1933ll avatharippicha estradiol benzoatinoppam, vaidyashaasthraparamaaya upayogathinaayi avatharippicha aadyathe estradiol esttarukalil onnaanu estradiol dipropionate. 1950kalil estradiol vaalarett, estradiol saipiyonettu thudangiya deerghakaala pravartthanamulla estradiol esttarukal vikasippikkunnathinum avatharippikkunnathinum munbu, estradiol dipropionate, estradiol benzoate ennivayaayirunnu ettavum vyaapakamaayi upayogichirunna estradiol esttarukal.
samoohavum samskaaravum.
pothuvaaya perukal.
estradiol dipropionate ennathu marunninte pothuvaaya peraanu, athinte,,,,.
brand perukal.
agopholin, acropholin, dihydropholina "keval", dimenformon, dimenformon dipropionate, diovosyline, dye-ovosailin, diprostrone, diprovx, endopholicolina dii ennivayulppede vividha brand namangalil estradiol dipropionate vipananam cheyyappettittund.pii.iii. pii. hormon dippo (hydroxy projastaron kaaproyettumaayi samyojippichu), estroi, eastronex, folicycline, folicycline pii, follycailmon dippo, horican-dippo, neysiklil, ostraadiyol galenica, ostraadiyol strauli, oropholina, ovaakrin, ovahormon dippo, ovosilin, ovosilin dipropionate, ovosilin pii, projinon dipi enniva ulppedunnu. munbu check republicilum slovakiayilum vipananam cheythirunna estradiol dipropionettinte enna layaniyaayirunnu agopholin.
labhyatha.
mikka raajyangalilum estradiol dipropionate nirthalaakkiyittundi jappanilum macedoniayilum maathram ovahormon, ostraadiyol galenica ennee brand namangalilum koodaathe/allengil hydroxy projestrone kaaproyettumaayi chernnu iii. pii hormon dippo enna brand naamatthilum labhyamaan. austreliyayil repair enna brand naamatthil hydroxy projestrone kaaproyett, nandrolon decanoyate ennivayumaayi samyojippichu vettinari medisinil upayogikkunnathinum ithu vipananam cheiyunnu.