cadifly silk

lepidoptere pattunoolppuzhukkalkk ("bii") samaanamaayi cadifostly (tricoptere) pattunool grandhikal sravikkunna pattaan cadifostly pattunool. morrie "). laarvakal vettayaadunnathinum svayam prathirodhikkunnathinum putt upayogikkunnu. pattukalkk vellathinadiyil bandhippikkunna gunangal nilavilulla shaasthreeya gaveshana vishayamaan.
cadisphly silk (fibroin).
tricoptere allengil cadisphly laarvakal avayude jala paristhithiyil vettayaadunnathinum svayam samrakshikkunnathinum putt upayogikkunnu. pattunoolppuzhukkaleppo (bii. morrie), mattu lepidoptere, eee silk protein prathyeka silk grandhikal visarjjikkunnu. pattunool ghadana kooduthalum vividha caddifly enangalkkidayil samrakshikkappedunnu, parakal, vadikal, chillukal, shellukal ennivayulppedeyulla avashishtangal bandhippikkanum iraye pidikkunnathinayi valakal nirmmikkanum ithu upayogikkaam. larva ghattathil avarude jeevithachakrathinte bhooribhaagavum chelavazhikkunna cadisflikalkku avarude underbailikaleyum pupettineyum samrakshikkaan eee casingukal aavasyamaanu. caddifly silk valare shakthavum modiyullathumaanu. poornnamaayum vellathil mungikkidakkumbol avayude pattinu vividha gadakangalumaayi bandhippikkaan kazhiyanam ennathinaal, jalanirodhitha pasha enna nilayil saadhyamaaya prayogangalkkaayi ithu padikkunnu.
protein ghadana.
yathaakramam 450,250 amino assid avashishtangalulla bhaarameriyathum bharam kuranjathumaaya fibroin proteinukalude oru heterodymeraanu cadisphly silk. lepidopteraykku samaanamaayi, tricoptere echu, ell fibroin ennivayum rund proteinukaludeyum disulfide linkejinu aavashyamaaya samrakshitha sisttain avashishtangal pradarshippikkunnu. lepidopterayude fibroin diameril ninnu vyathyasthamayi, tricoptere dimerukalkku pii 25 protein escort cheiyunnilla, orupakshe tricopteran fibroyininte vardhicha hydrophylicity anaavasyamaayathinaal. tricoptera echu-fibroyinil lepidopattera fibroyinil kaanappedunnathin samanamaaya aavarthichulla β-sheett roopangal adangiyirikkunnu, ithu proteinil aavarthikkunna kramatthil kaanapedunna uyarnna samrakshitha prolin-glycine teenn, tricoptera silk fiberukalkkullil kaanapedunna uyarnna kristalin ghadana ennivayaal savisheshamaan. ennirunnaalum, pattunoolppuzhukkalude fibroyinil glycine, alanine enniva adangiya β sheettukal adangiyirikkunnuvenkil, tricoptera fibroyininte β sheett motifil ganyamaayi vyathyasthamaaya amino assid makeup adangiyirikkunnu. cadisphly echu-fibroyininte β-sheett roopathinu (sx) 4 aavarthana paatten undennu kandethi, athaayath serin saadhaaranayaayi isolucin allengil valin upayogichu marimari varunnu. echu-fibroin proteinil udaneelam, ellah serinukalilum 60 sathamaanathiladhikam phosphorylated aayirunnu. negatteevu chaarjukal saadhaaranayaayi β sheettukalude asthirappeduthalaayi kanakkaakkappedunnundu, β rooparekhaykkullil avayude sthiramaaya roopam oru puthiya ghadanaye soochippikkunnu. eee negatteevu charjju cheytha group soochippikkunnathu hydrajan bontingin pakaram ionic edapedalukal cadisphly silkkinte asaadhaarana sakthiye vishadeekarikkaam ennaanu. molaskkukalilum kadal vellarikkakalilum ulppede mattu underwater bioadahesivukalil phosphorylated serinukal kandethiyittundu.
ionic edapedalukal.
cadisphly laarvakalude kanatha phosphorylated β-sheettil sakthamaaya negatteevu chaarjukal adangiyirikkunnu, avaa laarvakalude jala paristhithiyil swaabhaavikamaayi kaanapedunna dii-, trivalent kaattiyanukalumaayi edapazhakunnuvennu kandethi. kaalsyam, magneeshyam, irumbu ennivayulppedeyulla eee katteshanukal silkkinte β-sheettinte karkkashamaaya ghadana nilanirthunnathinu pradhaanamaan. negatteevu charjju cheytha serinukalum eee kaattiyanukalum thammilulla ionic edapedalukal ex-reey defraction nirnnayikkunnathupole 5.9 angstroms x 23.3 angstroms x 17.3 angstroms yoonit sellullah oru kristtal uthpaadippikkunnu. eee kaatteshanukalude aavasyakatha chelettu cheyyaanum protein ghadanayil ninnu neekkam cheyyaanum edaa upayogichu kaanikkukayum oru chalanathmakavum nonkristalin protein uthppaadippikkukayum cheythu. monovalent ayonukalude punarpraveshanam kristalin ghadana punasthaapikkunnathil parajayappettu, ennirunnaalum kaalsyamo mattu multivalent ayonukalo veendum avatharippikkunnath echu-fibroin proteinilekkulla kaadinyam vijayakaramaayi punasthaapichu.

