
hyoog mcdonald synclair

hyoog mcdonald synclair, efrcp (4 februvari 1910-22 juun 1990) oru medical doctor manushya poshakaahaarathekkurichulla gaveshakanumaayirunnu. coronary hrudrogam, cancer, prameham, veekkam, strock, charmmarogam thudangiya "naagarikathayude rogangal" ennu thaan vilikkunnavaye "mosham kozhuppukal" kooduthal vashalaakkunnuvenn avakaashappedunnathinaanu addeham ettavum kooduthal ariyappedunnathu.
aadyakaala jeevitam.
kenal hyoog montgomery synclairinteyum rosali sibil jaxoninteyum naalu makkalil moonnaamanaayirunnu hyoog mcdonald synclair. thante pithaaviloode addeham finlandile wiking rajaavaaya voldoniasinteyum vijayiyaya vilyaminte sent clair kasinsinteyum pingamiyaayirunnu. addehathinte muthachan aarr. tii aayirunnu. hohn. britiish board oof agrikalcharinte sthaapakanum prasidantumaaya sarr joonn synclair bii. tii. empy, avarude randaamathe bhaaryayaayirunnu. dveepukalile prabhu mcdonald alexanderude eaka makalaanu diana mcdonald. addehathinte godfadar cussin sarr archibald synclair liberal party nethaavum vinsttan charchilinte yudhakaala manthrisabhayile stettu phoor eyar sekrattariyumaaya wiscond turzo aayirunnu. addehathinte maathrpithaavaaya sarr joonn jaaksan prashastha enchineeyaraayirunnu.
duke oof aberconil ninnu vaadakaykku edutha skotlandile edinburghile duddingston housilaanu hyoog janichathu.
vidyaabhyaasam.
synclair thante mootha sahodaran jonine pinthudarnnu stoon house skoolilekkum pinneedu 1923 muthal 1929 vare winchester kolejilekkum pooyi, 1928 leeii headmasterude naachural sayans sammaanavum 1929 leeii seeniyar sayans sammaanavum labhichu.
aaa varsham, addeham ooksfoordile ooriyal collegil mrugangalude shareerashaasthram padikkaan pooyi, athil moonnu varshathinu sesham biochemistryil departmental demonstratoraayum pinneedu ooksfoordile magdalan collegil seeniyar demiyayum niyamikkappettappol addeham aadya nettam kaivarichu. 1933ll addeham goach memorial sammanam nedi.
landanile yooniversitti koleju hospital medical schoolil klinikkal medisin padicha addeham sosaitti oof apothecaries (elmsa), maasttar oof arts (ema), baachilar oof medisin, baachilar oof sarjari (bh, bisi), swarnna, velli medalukal ennivayil licensiat yogyatha nedi. samaantharamaayi addeham landanile yooniversitti collegil physiologyil prabhashakanaayirunnu.
1937-leeii venalkkaalath poshakaahaara gaveshanathil earppettirikkunna usl canadayileyum pala laborattarikalilum vipulamaaya sandarshanam nadatthaan addehathe anuvadicha radcliffe travelling fellowship addehathinu labhichu, ennaal magdalen kolejile physiology, biochemistry ennivayil audyogika fello tutor aayi thiranjedukkappettathinaal addehathinu yathrakal vettikkuraykkendivu, thudarnnu yooniversitti lakcharar, biochemistry demonstrator, 1937-1947 aayi niyamanam labhichu.
shaasthrajeevitham.
ooksfoord nutrition sarway.
1939-ll yudhathinte thudakkathil, synclair biochemistry vakuppile professor rudolph peettezhsinte keezhilulla oru vitharana samghathil chernnu, vishavaathakathin prathirodha nadapadikal thedi, pakshe janasamkhyayude poshaka nilayum athu engane vilayiruthaam ennathum synclairine kooduthal kooduthal pidichedukkaan thudangi. niravadhi sanbarkkangalude sahaayathode, synclair ooksfoord nutrition sarway ennariyappetta sthaapanathinulla nirddeshangal thayyarakki samarppichu. rund praadeshika kaundikalile regional medical kaunsilineppole aarogya manthraalayavum nirddeshangal amgeekarichu. doow. hugg smithinte shramangaliloode rockfeller foundeshanil ninnu sakthamaaya pinthuna labhichu. oduvil ooksfoord sarvakalashaala yoonittinte utharavaaditham amgeekarikkukayum synclairine sarveyude directoraakkukayum cheythu.
shekharikkenda daattayil naravamshashaasthra alavukal, klinikkal vilayiruthal, rakthathekkurichulla shaareerika nirnnayangal (haemoglobin, kattapidikkanulla samayam, chuvanna, velutha koshangalude ennam, phoosphett, motham vitaamin bii 1, cocarboxylase, vitaamin sii, vitaamin bii 2, nicotinic assid), moothram (naitrajan, vitaamin sii, vitaamin bii 1 ennivayude alavu 4 manikkoor akale edutha rund saambilukalil), vishwal dark adaptation enniva ulppedunnu.
aarogya manthraalayathile cheef medical offeesaraaya sarr vilyam jaimson ettavum upayogapradamaayathu "pakuthi peju" sarway pinthunayulla urappukal aanennu synclair theerumaanichu, raajyathinte poshakaahaara nila thripthikaramaanennu soochanakal, vishadamaaya pepparukalekkaal, amgeekritha piyar review cheytha shaasthreeya jenalukalil samarppikkaan anuyojyamaanu. eee theerumaanam nirantharamaaya vimarsanathinu kaaranamaayi.
ooksfoord poshakaahaara sarveyude oru bhagam oru cheria mobail teamaanu nadathiyathu, athu akrington, merthir, chesterfield, dundy thudangiya vyaavasaayika pattanangalilekku ayachu. eee pravartthanam samghadippikkunnathilum kaikaaryam cheiyunnathilum synclairinte anubhavam kanakkileduthu, pravaasatthilaayirunna dutch sarkkar europile yudhathinte avasana maasangalile shaamam baadhicha dutch janasamkhyayude poshakaahaara nilayekkurichu sarway nadatthaan addehathe kshanichu (1944-45-leeii dutch shaamam kaanuka). tirakkeriya thayyaareduppukalethudarnnu, synclair samghavum jarmman keezhadangunnathinu thottumunbu poshakaahaara sarway grouppaaya shaifai (supreme headquartezhs alide expeditionary fozhsu) netherlandsilekku pooyi. verum randaazhchaykkullil 26,000 biochemical vishakalanangal nadathiyathaayi parayappedunna oru bays addeham lidenil kandethi. ooksfoord teaminteyum avarude dutch sahapravarthakarudeyum pravartthanatthinte druthagathiyilulla vegatha nirashaajanakamaaya saahacharyathinte anantharafalamaayirunnu. kshaamatthinte avastha vilayiruthukayum chikitsa prathikaranavum rekhappeduthukayum samanamaaya saahacharyangalil bhaaviyile pravartthanangal ariyikkunnathinayi phalangal thayyarakkukayum cheyyendathundu. koodaathe, ettavum mikacha chikilsakal thirichariyukayum prayogikkukayum venam.
addehathinte nettangalkku, netherlandsile raajnji synclairine oranje-nassaavinte kramatthil oru shevaliyarayi niyamichu.
1945ll mobail laborattarikal dusseldorfilake kondupokaan synclairine kshanichu, avide addeham britiish kantrol commission vendi poshakaahaara sarway grouppinte aasthaanam sthaapichu. ooksfoordileyum mattidangalileyum sahapravarthakaril ninnu varacha nethaakkalude keezhil vividha nagarangalil anchu teamukal roopeekarichu synclair veendum samghadanayude asaadhaarana nettangal kaivarichu. synclairine oonarari brigediyaraakkukayum pinneedu yuu nalkukayum cheythu.ezz. vellippanayodukoodiya presidential medel oof freedam.
ooksfoord nutrition sarway 1946-ll aupachaarikamaayi avasanippikkukayum 1947-ll nutrition sarway group avasanippikkukayum cheythu. yudhathinushesham synclair sthaapikkumennu pratheekshichirunna human nutrition departmentinu pakaram, addehathe laborattari oof human nutrition director niyamichu, ooksfoordile charchil ashupathriyil kurachu nizen kudilukal anuvadichu, athu aduthide yuu. ezz. purathirakkiyirunnu.ezz. sakthikal. sarveyile mikka upakaranangalum chila jeevanakkarum laboratoric paarambaryamaayi labhichu, pakshe thaamasoukaryamalla. 1951ll manushya poshakaahaaratthile aadyathe sarvakalashaala vaayanakkaaranaayi addeham niyamithanaayi. 1954ll hans adolph crebs sarr rudolph peettezhsinte pingamiyaayi professor biochemistry vakuppinte medhaviyum aayi, athilekku laborattari maattukayum taamasiyaathe adachupoottukayum cheythu.
lansettilekku" enna kathu.
1956-ll synclair poshakaahaarathinu ettavum vyaapakamaayi ariyappedunna sambhavana nalki, "avashya phaatti aasidukaludeyum rakthapravaahathinteyum kuravu, muthalaayava" enna thalakkettil "laansettin" ezhuthiya oru kathinte roopathil. shwaasakosha arbudam, coronary thrombosis, raktarbudam ennivayaayirunnu muun varshangalil ettavum kooduthal vardhicha maranakaaranam, iva moonninum avashya phaatti aasidinte (iii. eph. eiii) kuravu pradhaanamaanennu synclair vishwasichu. efayude kuravu epidermisil collustroll esttarukal adhikamaayi nikshepikkaan kaaranamaakunnu. tetranoic arachidonic aasidaan ettavum pradhanappetta eefa ennu synclair karuthi. ithinte jaivasamshleshanathinu vitaamin bii6 aavasyamaanu. kozhuppukal kadinamaakkunnath ephas kuraykkukayum kuranja verthirichedukkal valarchayilekku maarunnath vitaamin bii6-nte alavu kuraykkukayum cheiyunnu. chlorin dye ooksaid polulla mechappeduthalukal, athine samrakshikkunna eathenkilum ifah vitaamin iii yeyum nasippikkunnu.
asaadhaaranamaaya phaatti aasidukal upayogichu esterify cheytha collustroll eluppathil illaathaakkappedaathinal athu rakthapravaahathilekk nayikkunnu. asaadhaaranamaaya phaatti aasidukal adangiyirikkunna phospholipidukalum eluppathil illaathaakkappedunnu, athinaal avaa plaasmayil nilanirthukayum rakthathinte urakkakkurav vardhippikkukayum cheiyunnu, athuvazhi coronary, cerebral thrombosis ennivaykku kaaranamaakunnu. epidermisilum kudalilum saadhaarana phospholipidukalude kuravu avayude ghadanaye thakararilaakkunnu, athinaal seboroic eksimaykkum peptik alsarinum kaaranamakum. athupole, saadhaarana phospholipidukalude kuravo naadeevyavasthayil asaadhaaranamaaya phospholipidukalude saannidhyamo demilination ulppedeyulla thakaraarulla gadanayilekku nayikkunnu, ithu multiple sclerosis, orupakshe maanasikarogam ennivaykku kaaranamakum. ephaasukalude kuravu ex-reey, kemikkal carsinogens ennivaykkulla saadhyatha vardhippikkum, aadyathethu randaamathethu rakthaarbudathilekkum randaamathethu brongasinte carsinomayilekkum nayikkunnu, purushanmaaril vayarile carsinomayude praadhaanyathilekku, ephaasinulla purusha aavasyakatha sthreekalil ninnu anjirattiyaanu.
kathinte bhooribhaagavum oohaapohangalum chila abhipraayangal aneethiyumaanu. ennirunnaalum, ithu oru naazhikakkallayi maarukayum oru varshathilere kathidapaadukalilekku nayikkukayum cheythu. eee prabandhathinu purame, eee kaalayalavil, vitaamin eyudeyum avashya phaatti aasidukaludeyum kurravukal elikalile follicular hypercaratosisumaayi bandhappettathum, pyridoxine kurravil elikalile mucocutaneous sonukalude shathangal, ginia pannikalile hypervitaminosile ascorbic assid eiii, pyridoxine kurravil elikalile polycytemia, avashya phaatti aasidukalude kurravil charmmatthinte praveshanakshamatha, madyapaanathilum vittaaminukalilum naadeevyavasthayilum vaitamin kurravukal, elikalile vittumaaraatha tayamin kurravil poshakaahaara neuropathy thudangi pothuvilum kooduthal nirddishta vashangalilum vividha vishayangal synclair prasidheekarichirunnu.
1958-ll, synclairinte vaayanakkaarude aadya thiranjeduppu kaalayalav avasaanichu, addehathinte chinthakalude vishalamaaya vyapthiyum moulikathayum undaayirunnittum parambaraagatha shaasthreeya saahityathinu addeham nalkia sambhavanakal aparyaapthamaanennu vilayiruthappettathukonum addehathe veendum niyamichathu.
amgeekaaram.
synclair inii biochemistry vibhaagathil amgamaayirunnillenkilum addeham magdalanil adthyaapakanaayi thudarnnu, prachodanaathmakavum vinodakaravumaaya prabhaashakanenna khyaathi kaaranam addehathe vyaapakamaayi prabhashanam nadatthaan kshanichu. thante gaveshanathinum oru manushya poshakaahaara sthaapanathinum, thante vishalamaaya sanbarkkangalil ninnu, prathyekichu loard bosom, yudhakaalathe bhakshyamantriyaaya loard voolttan (1940-1943) ennivar vazhi pinthuna uyarthaan addeham kadinamaayi shramichuvenkilum, pradhaanamaayum thante sahodari kaatharinte vaahanaapakadathil undaaya maranatthinte njettalinte anantharafalamaayi, thaan cheythekkaavunnathra kadinamaayi addeham thante cases munnott kondupoyilla. ekadesham 61⁄2 varsham munbu 1954ll hrudrogam moolam addehathinu sahodarane nashtappettu. 1964ll loard woolton 1965ll loard bose marichu.
synclairinu mattu vazhikaliloode amgeekaaram nalkunnathu thudarnnu. angane addeham 1951-ll harwardil cutter lakcharar, 1967-1968-nulla poojaneeyamaaya sosaitti oof appothakkarikalude maasttar, 1968-ll baldwin-wallace collegil ninnu oonarari dsc, 1969-ll landanile saandezhsan-wells lakcharar, mccarrison sosaitti president 1983-1990 ennee padavikal vahichu.
inyoottu diet pareekshanam.
1953ll inyoottinte bhakshanathekkurichu synclair aadyamaayi ezhuthi. 1966ll addeham trontheimil prabhashanam nadatthi, avide addeham thante thalpparyam puthukki. 1976-ll, vadakkupadinjaaran greenlandile baang aandu dierberg paryaveshanatthil cheraan addehathinu kurachu samayam chelavazhikkaan kazhinju, ithu addehathinte ettavum prashasthamaaya pareekshanatthilekku nayichu, athil 1979 march muthal 100 divasathekku seal, malsyam (molaskkukal, crustatians ennivayulppede), vellam enniva maathram ulkkollunna inyoottu dietil addeham svayam earppettu. niravadhi vishakalanangal nadatthi platelettukalude angeyattatthe vibhajanam nireekshikkappettu, rakthasraavam 3 minittil ninnu 50 minittiladikam uyarnnu, oppam swaabhaavika rakthasravavum. (inyoottu mookkil ninnu raktham varunnathayi ariyappedunnu.) platelettukalude shekharanam kuraykkunnathilum angane thrombosis undaakunnathum kuraykkunnathil malsya ennakalude long cheyin phaatti aasidukalude praadhaanyatthinte naadakeeyamaaya prakadanamaayirunnu eee pareekshanam.
thudarnnulla currier.
1968ll ooksfoordile biological sciencesil yooniversitti lactureraayi synclair niyamikkappedukayum 1970ll reeding yooniversittiyil phudu sayansil visitting professoraayi niyamikkappedukayum avide addeham maranavarsham vare prabhashanangal thudarnnu. ivayil ettavum pradhaanappettava wacker (1990) ezhuthiya pusthakatthil ulppeduthiyittundu.
ooksfordinaduthulla vipulamaaya maithaanamaaya nuneham parkkil thante instittyoott kandethaamenna prateeksha chila samayangalil synclair niravettiyirunnuvenkilum 1933ll amma vangiya ooksfordinaduthulla thante veedu, lady plays, sattan courtaine upayogikkuka ennathaanu ettavum praayogika maarggamenn kramena addeham manassilakki.
1972-ll, association phoor dhii stadi oof human nutrition limittadinte memmoraandavum articles oof association oppuvachu, varikkaraaya hyoog synclair, francis ileward, richard doll, arther eliot-smith, david paattan cuthbertson, herbert keeii, joonn talbot, solisittar. pinneedu association oru chaarittiyaayi rajisttar cheyyappettu. synclair athinte director. taamasiyaathe peru internaashanal instittyoott oof human nutrition ennum pinneedu internaashanal nutrition foundeshan ennum maatti. varshangal kazhiyunthorum ghadana marria kaunsilil cheraan loard porittine kshanichu
manushya poshakaahaaratthinte hyoog synclair yoonit.
lady placeil oru ganyamaaya instittyoott nirmmikkaan synclair padhathiyittirunnu. ambathu thozhilaallikalkulla laborattari soukaryangal ulppeduthunnathaayirunnu ithu, oru prabhaashana thiyettar, oru museum, offeesukal, oru library enniva ulppede, sarjan-kyapttan thomas ell. sarr roobert mccarrison ulppede 300,000-tholam punarmudranangalum pusthakangalum addehathinte shekharathil ulppeduthuka. cleave, neel painter, hugg troval, sisili vilyams. addehathinte bhooribhaagam samayavum panam swaroopikkaan sramikkunnathil muzhukiyirunnuvenkilum, sthreesthalathu krameekarichirunna thaalkkaalika thaamasthalathu instittyoottinte pravartthanam synclairil ninnulla vyakthiparamaaya saambathika sambhaavanakale valareyadhikam aashrayichirunnu. addeham thante muzhuvan swathum foundeshanu vittukoduthu.
lady placeil gaveshana vikasanathinte nerittulla utharavaaditham ettedukkendathillenna maanejment kaunsil theerumaanichu, marichu oru sarvakalashaala manushya poshakaahaaratthil oru cheyar sthaapich synclairinte abhilaashangal kooduthal munnott kondupokaan aagrahikkunnundo ennu nokkaan. athanusarichu, nirddeshangal shanikkukayum samarppicha nirddeshangalude aapekshika gunangal vilayiruthunnathinayi poshakaahaaratthil anthaaraashtra vidagtharude oru paanaline niyamikkukayum cheythu. avasana roundil, moonnu malsaraarthikal undaayirunnu ooksfoord brooks yooniversitti, ooksfoord yooniversitti, yooniversitti oof reeding. avasaanatheth vijayakaramaanennu theliyikkukayum, kaalakramena, foundeshan avasanippikkukayum manushya poshakaahaaratthinte hyoog synclair yoonit reeding sarvakalashaalayil sthaapikkukayum cheythu. 1995-ll kristeen vilyams aadyathe hugg synclair professoraayi niyamikkappedukayum mattu jeevanakkaarude niyamanam athivegam nadakkukayum cheythu.
hyoog synclairinte jeevithatheyum nettangaleyum kurichulla melpparanja vivaranam pradhaanamaayum evin (2001), gail aandu lloyd (1990) ennivayude prasidheekaranangale adisthaanamaakkiyullathaanu.
sthree sthaanam.
1990ll synclairinte maranashesham sattan courtneyile mookk-tudor maalikayile lady plays, synclair hoome, yooniversitti oof reeding upayogichirunnu. 1998 august 28nuu theepidutthatthil ithu nasippikkappettu; thudarnnu oru pradesavaasiye theeveppu kuttangalil ninnu ozhivaakki. 2000-ll eee sthalathu oru estettu veedukal nirmmichu, bhavanathinte sthaanam araa thadi appaartment blokkumaayi.

