
gwendallin jeey. randolf

gwendallin jeey. emiline aarr enna american rogaprathirodha vidagthanaanu randolf. sent. washington sarvakalaashaalayile immunology aandu pathology vibhaagathile vishishta professor. luis, misauri, avide avar nilavil immunology biruda prograaminte saha directoraan. thante poost doctoral jolikkidayil, randolf dendritik koshangalumaayum macrophageukalumaayum monoosait verthiriv savisheshamaakkukayum dendritik kosha kadathum veekkam ulla sthalangalilekku recruit cheyyappedunna monocytukalude vidhiyekkurichum nammude daaranaykku purogathi kaivarikkukayum cheythu. macrophage jeane expression savisheshatha nalkikkond avarude laab rogaprathirodha janithaka padhathikku sambhavana nalkiyittundu. lymphatic pravartthanavum lipoprotein kadathum paryavekshanam cheythukondu rakthapravaham, koshajwalana malavisarjanam (ibd) ennivaykku kaaranamakunna rogaprathirodha samvidaanangalil avarude pravartthanam ippol shradha kendreekarikkunnu.
aadyakaala jeevithavum vidyaabhyaasavum.
texasile hart enna cheria kaarshika pattanathilaanu gwendallin vilson enna peril janicha randolf janichathu. kalakal paripalikkukayum vilaveduppil sahayikkukayum cheythukondu mcculkkum paruthikkoottinum vendi maathaapithaakkale sahayikkunnavalaayi avar valarnnu. hart haiskoolile schoolil, designilum thunitharangalilum aadyakaala abhinivesham prakadippicha avar thunnal nettangalkkaayi newyorkkilekkum loss enjalsilekkum yaatra cheyyaan avaardukalum dhanasahayavum nedi. 1987ll texasile plainviewile weyland baptist yooniversittiyil basketball kalikkaan sports scholarship sweekarikkukayum jeevashaasthrathil birudam nedukayum cheythu.
1989-ll avar keytt randolfine vivaham kazhichu; avar kizhakkan theerathekku thamasam maari, avide avar pensylvaniayile filadelfiyayile temple yooniversittiyil patanam thudarnnu. 1991ll avar biological sayansil baachilar oof sayans birudam nedi. 1995ll stooni brookile stettu yooniversitti oof newyorkkil ninnu immunology aandu patholajiyil phd nedi. maartha bii. yude maarganirdeshaprakaaram pravartthikkunnu. furie thenocyte migration padikkunnu.
rockfeller sarvakalaashaalayilum cornell sarvakalaashaalayile weyl medical collegilum sellular immunology aandu pathology vakuppukalil poost doctoral parisheelanathinaayi randolf newyorkkil thaamasichu. dendraitik sell pakwathayum kudiyettavum padikkunna bill mullar, vascular biologist, ralph stainmaan ennivarude maarganirdeshaprakaaram avar pravarthichu.
dendraitik koshangalude pakwathayum kudiyettavum.
randolfinte poost doctoral pravartthanangal, steyinmaanumaayum mullarumaayum sahakarichu, dendraitik koshangalude vyathyasathekkurichum chuttalavil ninnu lymph nodukalilekkulla avayude kudiyettathekkurichum anweshichu. dendraitik cellukaloo macrophageukalo aaya monoosait vyathyasam vilayiruthunnathinayi avar oru inn vitro model vikasippichu. endothelial koshangalumayulla monocytukalude sanbarkkam dissy deferentiationil nirnaayakamaanennum phagocytic kanangalumayulla sanbarkkam munbu reverse-traansmigrett cheytha koshangal intra sellular, extra sellular markerukal, uyarnna ramified phenotype ennivayude kaaryatthil dissy polulla phenotype poornnamaayum pradarshippikkaan kaaranamayennum avar kandethi. monocytukal sub-endothelial maatriksil thudarukayaanenkil avaye maakrofejukalaayi verthirichariyaan kazhiyumennum randolf kaanichu. eee padanatthe thudarnnu oru varshathinusesham immuniyil prasidheekaricha vivoyile eee kandethalukalude sthireekaranavum nadannu.
currier gaveshanavum.
1998-ll randolf weyl cornelle pathology vibhaagathil oru instructor rockfeller sarvakalaashaalayude sellular physiology aandu immunology vibhaagathil anubandha faakkalttiyumaayi. 2000-ll avar teey moundu sinaay school oof medisinil chernnu, avide avar jeane aandu sell medisin vakuppile faakkalttiyil 11 varsham chelavazhichu. emm. tii. yill. sinaay, avarude laab monoosait vidhiyum vyathyasavum paryavekshanam cheythu, koodaathe veekkam sambhavicha tissuekalil ninnu lymphatic naalangaliloode avaa kadathum. macrophageukalkku avayavangalil ninnu, lymphatics vazhiyo raktham vazhiyo, aarogyakaramayatho rogamullatho aaya avasthakalil kudiyeraan kazhiyumo ennu nirnnayikkuka ennathaayirunnu oru lakshyam; avaa anganeyallennu laborattari nigamanam cheythu. elikalil raktha monocytukal thirichariyunnathinulla aadyakaala laabukalil onnaayirunnu avarude laab, sidi115 nte expression upayogichu angane cheiyunnathinulla oru saarvathrika reethi vikasippicheduthu, myelooid koshangale kooduthal saadhaaranayaayi thirichariyaan upayogikkunna valare kuranja selective sidi11bii maatti. avarude laab eliyudeyum manushya monoosait upavibhaagangaludeyum thaarathamyangal nadathukayum myelooid koshangalude saarvathrika vargeekarana namakaranam srishtikkukayum cheythu.
randolf thante laab sent washington sarvakalaashaalayilekk maatti. luis 2011 ll, rakthapravaham, krons rogam thudangiya rogangalil collustroll kadathunnathinte punk padikkunnu. 2015 muthal 2017 vare avar washington sarvakalaashaalayile immunobiology divishante medhaaviyaayirunnu. avar nilavil emil aarr aanu. washington sarvakalaashaalayile pathology aandu immunology vibhaagathile vishishta professor. 2017ll avar school oof medisinil immunology graajvett prograam director 2020ll qoo-director aayi.
rogaprathirodha janithakapadhathiyum macrophage vaividhyavum.
elikalil rogaprathirodha samvidaanathinte pravartthanavumaayi jeane expression engane bandhappettirikkunnave paryavekshanam cheyyuka ennathaanu lakshyamidunna oru projectaaya immunological genome projectinu randolfinte laab sambhavana nalkiyittundu. mouse macrophage jeane eksprashanekkurichulla aadyakaala pravarthanangalkku avar neethrthwam nalki, immijen padhathiyude bhaagamaayi prasidheekaricha avarude prabandhamaanu padhathiyude ettavum uyarnna udharicha prabandham.
lymphatic vasculature collustroll kadathum.
washington sarvakalaashaalayilekk marria sesham rogaprathirodha kadathum lymphatic vasculature roga prakriyakalil cheluthunna prathyaaghaathangalilekkaanu randolfinte shradha maariyath. visarjjanathinaayi collustroll samaaharikkunnathin lymphatic naalangal nirnaayakamaanennum lymphatic pravartthanam vardhippikkunnathu rakthapravaahathil chikilsaaparamaakumennum avar theliyichu. macrophageukalkkum dendraitik koshangalkkum aantijanukal edukkunnathinulla oru sthalamaayi pravartthikkunnathiloode lymphatic naalangal (clv) shekharikkunnathu rogaprathirodha prathikaranatthil ulppedunnuvennu avarude laab pinneedu kaanichu. adipose depokalkku chuttumulla rogaprathirodha prathikaranangalude ekopanathil clvs pradhaanamaanennu phalangal oonnipparanju.  2018 ll, charmmatthil adhishtithamaaya rogaprathirodha prathikaranangal koshangal collustroll edukkaanulla kazhivine badhikkunna vyavasthaapitha maattangalkk kaaranamaakumenn avarude team kandethi, angane hridayathinu chuttumulla dhamanikalil plack nirmmikkunnath prothsaahippikkunnu. prathyekichum, pareekshanathmaka soriyaasisil kaanapedunna kolajan madhyastha maattangalkk th17 koshangal kaaranamakunnuvennum il17 thadayunnathu collustroll gathaagathathe rakshikkukayum rakthakkuzhalukalude kaadinyam kuraykkukayum cheiyunnuvennum avar kandethi.
2015-ll, gastroentrologist, jeane-frederic kolambalumaayi sahakarichu koshajwalana malavisarjana rogathil lymphaticsinteyum sellular gathaagathathinteyum punk padikkunnathinaayi uyarnna apakadasaadyathayulla uyarnna pratiphala gaveshanam nadathunnathinu randolfinu naashanal instittyoott oof health directorude 2015 pioneer award labhichu. elikalil kaanikkunnathupole lymphatic shekharana naalangalkk kedupaadukal sambhavikkunnath manushyarogathinu kaaranamaakumo ennu manasilakkaan, manushya mesentarik tissuevile lymphatic vasculature asaadhaaranathakal paryavekshanam cheiyunnathinaayi randolfinte laab oru trimana imaging sameepanam vikasippichu. eee puthiya sameepanam lymph nodukalilekkulla lymph asaadhaaranamaayi vitharanam cheiyunnathil ulppettirikkunna shekharikkunna lymphatic naalangalil puthiya thritheeya lymphoid avayavangal thirichariyaan avare anuvadichu.
vyakthiparamaaya jeevitam.
randolf ippol herman kairichenko vivaham kazhichu, rund kuttikalundu.

