kraya

manushyaril "kraya" jeane encode cheiyunna oru proteinaan alfa-kristalin cheyin.
christalinukale rund vibhagangalaayi thirichirikkunnu taxon-nirddishta allengil ensime, sarvvyaapiyaayava. randaamathe klaas kasherukkalude netra lensinte pradhana proteinukal ulkkollukayum lensinte sutharyathayum refractive soochikayum nilanirthukayum cheiyunnu. lense central fiber sellukalkk avayude nucleus vikasikkumbol nashtappedunnathinaal, eee christalinukal nirmmikkukayum jeevithakalam muzhuvan nilanirthukayum cheiyunnu, ithu avaye valare sthirathayulla proteinukalaayi maattunnu. sasthanikalude lense christalinukale alfa, beetta, gaama kudumbangalayi thirichirikkunnu; beetta, gaama christalinukalum oru suuppar faamiliyaayi kanakkaakkappedunnu. alfa, beetta kudumbangale acidic, basic grouppukalaayi thirichirikkunnu. christalinukalil ezhu protein mekhalakal undu naalu homologous motifukal, oru connecting pepttaid, enn-, sii-terminal ekstenshanukal. alfa-eiii, alfa-bii ennee rund jeane uthppannangal chernnathaanu alfa christalinukal, yathaakramam aciditic basicinum. alfa christalinukal choodu shock vazhi prachodippikkappedaam, avaa cheria heett shock protein protein ennum ariyappedunna ssp) kudumbatthile amgangalaanu. avaa proteinukal punarnirmmikkukayum yadhaartha chaaparoninte reethiyil purathuvidukayum cheiyunnillenkilum avaa molecular chaparonukalaayi pravartthikkunnu; pakaram avaa valia layikkunna aggregettukalil pidikkunnu. vivarthanaananthara mattangal chaapparon cheyyaanulla kazhivu kuraykkunnu. eee vaividhyamaarnna aggregettukalil 30-40 subunitukal adangiyirikkunnu; alfa-eiii, alfa-bii subunitukalkku yathaakramam 3:1 anupaathamund. alfa christalinukalude rund adhika pravartthanangal oru autokiness pravartthanavum intra sellular vaasthuvidyayile pankaalithavumaanu. alfa-eiii, alfa-bii jeane uthppannangal vyathyasthamayi prakadippikkunnu; alfa-eiii mungananayode lensil parimithappedutthiyirikku, koodaathe alfa-bii pala koshangalilum avayavangalilum vyaapakamaayi prakadippikkunnu. eee jeenile vaikalyangal autosomal dominant konjenittal timiram (eiii. dii. sii. sii) undaakkunnu.
ashayavinimayam.
krayab 2, echsp 27, crike, krayab ennivayumaayi kraya edapedunnathaayi theliyikkappettittund.

