functional molecular infection epidemiology

functional molecular infection epidemiology (efmi) ennathu rogakarikalaaya jeenukaleyum genomeukaleyum kurichulla padanavum avaa aathidheyarude edangalumaayulla (pasha, akramanam, poruthappedutthal) pravarthanaparamaaya bandhavum aathidheyarude rogaprathirodha samvidaanathinullil avaa prachodippikkunna sankeernamaaya edapedalukalum (sell signalling, apoptosis) anubaadhayude vividha phalangalil kalashikkunna vaidyashaasthrathinte uyarnnuvarunna mekhalayaanu. rogathinte theevratha, rogathinte purogathi, allengil oru prathyeka rogakaariyude saannidhyam ennivaykku pradhaanamaaya savisheshamaaya pravartthanavumaayi oru rogakaariyilo athath hosttilo ulla janithaka vyathiyaanangalude parasparabandhamaayum ithine nirvachikkaam. functional epidemiology ennathu vivaranathmaka hoost-pathojan genomic associationukale mathramalla, anubaadhayude samayat janithaka vyathiyaanangalude punk pravartthanaparamaayi prakadippikkunnathinaayi rogakariyum hoost genomic vyathiyaanangalum thammilulla parasparapravartthanathe soochippikkunnu.
functional molecular infection epidemiology classical molecular infection epidemiology ninnu vyathyasthamaan, pradhaanamaayum randaamathethu track cheiyunna ejantinte pravartthana/phenotypic swabhaavasavisheshathakalekkuri kooduthal aashankappedaathe pakarchavyaadhi ejantinte tagging tracking kaikaaryam cheiyunnu. maruvashathu, functional molecular epidemiology, hoost-pathojan edapedal, adaptation allengil homeostaasisinte genotypic, phenotypic parasparabandangalkk kooduthal oonnal nalkunnu. koodaathe, classical molecular epidemiology pradhaanamaayum insersion sequenceukalum intergenic gadakangalum polulla "neutral" markerukal upayogikkunnu, athesamayam functional molecular epidemiology snps, genome qoo-oordinettukal polulla pravartthanaparamaayi prasakthamaaya markerukal anubadha jeevashaasthrathile anumanaparamaaya pankukalumaayi upayogikkunnu-rogakariyum aathidheya vashavum. efmiyude prameyathinu anuyojyamaaya niravadhi padanangal nadathiyittundu-udaaharanathinu, micobacterium eaviyam subspiyude ettedukkalum kaimattavum. manushya jeane jeane oru saadhyathayulla hosttil prathyeka mutationukalkku vidheyamaakumbol type-1 pramehatthinte vikaasathil paaratyubarkkulosisum athinte pankum.
onniladhikam genome sequencingin vividha hoost/rogi janasamkhyayil ninnulla pradhana bacteria rogakaarikalude sequencingin sesham efmi enna ashayam prasakthamaayitheernnu.
lother echu. yude samyuktha neethrthwathil dii. eph. jii. dhanasahaayathodeyulla padhathi-jii. aarr. keey. 1673-yude bhaagamaayi pothujanaarogyathilum vettinari mekhalayilum eph. emm. aii. yude prayogam paryavekshanam cheiyunnathinum anweshikkunnathinum berlinile free sarvakalashaalayudeyum hyderabad sarvakalashaalayudeyum aabhimukhyathil indiayileyum germmaniyileyum shaasthranjarude oru kansorshyam (project bridge) ithinakam roopeekarichittundu. wheeler (berlin sarvakalashaala), niyas ahamed (hyderabad sarvakalashaala).

