
darodepine

mrugangalude modalukale adisthaanamaakkiyulla oru pareekshanathmaka kaalsyam chaanal blockeranu darodepine, ithu vaardhakyakaalathum neuro degenerative disordezhsilum neuronal cytoskelital mattangal kuraykkum. elikalil nadatthiya padanangal mastishka serotonergic samvidaanangale darodepine baadhikkumenn theliyichittundu. thalachorinte vividha bhaagangalil 5-hiah/5-echu. tii anupatham darodepine vardhippichu. elikalude oormmashakthiyeyum patana prakriyakaleyum darodepine thakaraarilaakkunnathaayi theliyikkappettittund.
daarodippinte deerghakaala prabhavam elikalil pareekshichu, avayude shareerathilum masthishkabhaarathilum kaaryamaaya maattamonnumillenn ithu kaanikkunnu, pakshe avayude alkaline phoosphett reactive capillary profile moolyangalil kaaryamaaya maattamund. cerebral capillary pravartthanangalude pravartthanatthil alkaline phoosphett ensimeukal oru pradhana punk vahikkunnu. plasmayude saandrathayil darodipin cheluthunna swaadheenam aarogyamulla oru koottam purusha sannadhapravarthakaril pareekshichu. falamaayi, plasmayude saandrathayumaayi bandhapetta hridayamidippil maattatthinum diastolic rakthasammardhathinum darodepine kaaranamaayi.
darodepine (50-500 nm), dii. emm. pii. oo-kooyude samvedanakshamatha.- dii. emm. pii. oo-ooo. oo. adakttinekkaal kooduthal adakt kurayukayum signal theevrathayil eakaagrathaye aasrayichulla idivu kurayukayum cheythu. free-radical mediated electrophysiological mattangalkkethire kaalsyam virudhatha kaaranam ithinu adhika prathirodha falangalundu; atharam radical thanmaathrakalude kenii moolamaanu ithu sambhavikkunnath.