
ida steefans ovens

mayakkumarunnu-detoxify cheiyunna ensaimukalumaayulla pravarthanatthinu peruketta oru american shaasthranjayaayirunnu ida steefans ovens (septambar 13,1939-februvari 24,2020). avalkk piechu labhichu.1967 ll duke sarvakalashaalayil ninnu birudam nedi, schoolil ninnu doktarettu nediya aadyathe rund aafrikkan amerikkakkaaril oralaayi avar maari. 1968 muthal 2017 vare pravarthicha naashanal instittyoott oof healthil (nih) avar thante currier chelavazhichu, avide avar manushyarogangaludeyum mayakkumarunnu mettabolisathinteyum janithakashaasthra padanatthinu thudakkamittu.
aadyakaala jeevitam.
vadakkan karolinayile vaittville enna cheria pattanatthile oru krishiyidathilaanu ida virgenia steefans ovens valarnnathu. avalkk aarr vayassullappol avalude amma marichu.
vidyaabhyaasam.
oovensinte aadyakaala vidyaabhyaasam verthiricha pothu skoolukalilaayirunnu. pinneedu north carolina central yooniversittiyaaya north carolina collegil chernna ovens 1961ll biologyil (bii.ezz.), ganitham (cheriyath). birudam nediya sesham, north carolina kolejile haiskool adhyapakarkkaayulla naashanal sayans foundeshan summer instittyoottil laborattari asisttantaayi jolie cheyyukayum oru venalkkaalam daniel sii. yude labil chelavazhikkukayum cheythu. duke sarvakalaashaalayile physiology vibhaagathil tosttasan. pinneedu, 1962-ll avar piechu. dii. aarambhichu.dii. laborattariyile biochemistry physiology kurichulla padanangal jacob jeey. sarvakalashaala athinte biruda, professional skoolukale vamsheeyamaayi samyojippichathin thottupinnaale blum attu duke. 1967ll birudam nediyappol, phd nediya aadya rund aafrikkan amerikkakkaaril oralaayi avar maari.dii. duke sarvakalashaalayil ninnu physiologyil eathenkilum birudam nediya aadya vanithayum.
shaasthrajeevitham.
birudam nediya sesham, aadyam biochemistry, metabolism laborattariyile naashanal instittyoott oof aarthraitis, metaboolik, digestive diseases ennum pinneedu naashanal instittyoott oof child health aandu human development (nichdi) laborattari oof biomedical sciencesile developmental farmacology vibhaagathil ovens nihile poost doctoral sthaanam vahichu. eee samayat, shareerathil marunnukal engane raasaparamaayi samskarikkunnu ennathil avar shradha kendreekarichu. 1975-ll, ovens nih nichdi-yill drugg bio transformation vibhagathinullil swantham swatantra gaveshana groupine nayikkaan thudangi, ithu pinneedu drugg mettabolisatthinte janithaka vaikalyangalekkurichulla vibhaagamaayi maari. nihile aadyathe aafrikkan american anweshakayaayirunnu avar. 1988 muthal, developmental endocrinology, janithakashasthram ennivayekkurichulla paripaadiyil mayakkumarunnu mettabolisatthinte janithaka vaikalyangalekkurichulla nichdinte vibhaagathin ovens nirddesham nalki.
shaasthreeyamaaya purogathi.
oovensinte poost doctoral pravartthanam yuu. dii. pii-glucuronosil transferesus (churukkatthil ugts) enna nirnaayaka ensaimukalude oru grouppilulla avalude prathyeka thaalpparyathinu kaaranamaayi, ithu doshakaramaaya marunnukal, rasavasthukkal, mattu vishavasthukkal enniva nirveeryamaakkaan shareerathe anuvadikkunnu. nirddishta yujidi ensaimukalkkaayi coode cheiyunna jeenukale gaveshanam cheiyunnathinulla reethikal roopakalppana cheythukondu, yujidi1eiii ennariyappedunna 13 jeenukalude oru samuchayam avar thiricharinju. eee jeenukalilonnaaya yujidi1eiii1, haemoglobinte thakarcha ulppannamaaya protein bilirubin prosess cheiyunnuvennu avarude laab kaanichu.
oovensinte gaveshana samgham pinneedu yujidi ensime bayolajiyekkurich onniladhikam purogathikal kaivarichu. avarude laborattariyaan aadyamaayi criggler-najjar syndrome nayikkunna yujidi1eiii1 jeenil janithaka vaikalyam kandethiyathu. bileerubinte saadhaarana parishkkaranatheyum visarjjanatheyum thadassappeduthukayum manjappitham varaanulla kaaranamavukayum cheiyunna oru rogamaanu criggler-najjar syndrome. videsha raasavasthukkale vishaamsham illaathaakkunnathinu munbu yujidi ensimeukal sajeevamakkanamennum chila sandarbhangalil eee ensimeukal adichamarthunnathu chikitsa marunnukalude phalangal vardhippikkumennum oovensinte gaveshana samgham thiricharinju. kinace inhibittarukal vazhi yujidi ensaimukalude pravartthanam kuraykkaamennum protein kinace sii, tyrosine kinace ensimeukal ennivaykku ensaiminte prathyekathayil maattam varuthaan kazhiyumennum ithu vaividhyamaarnna videsha raasavasthukkale vishaamsham illaathaakkaanulla kazhivilekku sambhavana cheyyumennum oovensinte laborattari kandethi.
bahumathikal.
ovensinu 1992-leeii niha director award 2013-ll duke yooniversitti graajvett skoolinte aadyathe vishishta poorvva vidyaarthi award labhichu. koodaathe, 2009-ll, american aasthma foundeshan farmacology jenalukalile udharicha rachayithaakkalil ettavum mikacha 5 sathamaanathil oralaayi ovensine amgeekarichu.

