
prostettu cancer parisodhana

adayaalangalo lakshanangalo illaathe purushanmaaril roganirnayam nadathaattha prostettu cancer kandethaan upayogikkunna screening prakriyayaan prostettu cancer screening. asaadhaaranamaaya prostettu tissue allengil cancer neratthe kandethumbol, chikilsikkaanum sukhappeduthaanum eluppamaayirikkum, ennaal neratheyulla kandethal marananirakk kuraykkunnundo ennu vyakthamalla.
roganirnayathinum thudarnnulla chikilsaykkum munbaayi screening nadathunnu. malaashayathinte mathililoode prostettu swamedhayaa vilayiruthunna oru screening upakaranamaan digital malashaya parisodhana (dii. aarr. iii). rakthathile prostettu-specific aantijan (psa) alakkunnathaanu randaamathe screening upakaranam. psa allengil dii. aarr. iii upayogichu screening cheiyunnathu prostettu canceril ninnulla marananirakk kuraykkunnundo ennu nirnnayikkaan thelivukal aparyapthamaanu. 2013 leeii oru cochrain avalokanam psa screening phalangal "prostettu cancer-nirddishta marananirakkil sthithivivarakkanakkukali kaaryamaaya vyathyasamilla" ennu nigamanam cheythu...". american padanangal uyarnna pakshapaatham pularthunnuvennu theerumaanichu. eee avalokanathil ulppeduthiyittulla europian padanangal pakshapaatham kuravaayirunnu, oraal "prostettu cancer-nirddishta marananirakkil ganyamaaya kuravu" report cheythu."eee avalokanathil dii. aarr. iii. upayogichulla pii. ezz. eiii screening vilayiruthiyitilla. dii. aarr. iii prathyekamaayi vilayiruthiyitilla.
screening cheyyanamo vendayo enna theerumaanam pankitta theerumaanamedukkaline adisthaanamaakkiyumenathiraayi ettavum puthiya maargganirddeshangal shupaarsha cheythittundu, angane screeninginte apakadasaadhyathakaleyum nettangaleyum kurichu purushanmaare ariyikkunnu. 2012ll american sosaitti oof klinikkal oongoolaji patthu varshathil thaazhe jeevikkaan aagrahikkunnavare screening niruthsaahappeduthanamenna shupaarsha cheiyunnu, athesamayam kooduthal aayurdairkhyamullavarkku oru theerumaanam edukkendathu chodyam cheyyappedunna vyakthiyaan. pothuve, sameepakaala gaveshanangale adisthaanamaakki, "prostettu cancer parishodhanaykkulla psa parishodhanayumaayi bandhapetta nettangal screening thudarnnulla anaavashya chikilsayumaayi bandhapetta doshangalkku yogyamaano ennu urappilla."ennirunnaalum, 2022 maarchode, europian kammeeshante shaasthreeya upadesha samvidaanathinte ettavum puthiya thelivukal avalokanam cheytha vidagdhar saankethika mechappeduthalukal kaaranam doshangaludeyum nettangaludeyum santhulithaavastha maariyenn vidhichu, rakthaparisodhana upayogichu janasamkhya thalatthil prostettu cancer parisodhana samghadippikkaan aadyamaayi shupaarsha cheythu; atharam screening paripaadikalkk purathulla lakshanangalillaatha vyakthikalkk avasaravaada parisodhanakal nalkunnathinethire avar prathyekamaayi upadeshichu.
prostettu cancer nirnnayikkaan prostettu biopsykal upayogikkunnu, pakshe rogalakshanamillaatha purushanmaaril ithu cheiyunnilla, athinaal screening cheyyaan upayogikkunnilla. prostettu biopsic sheshamulla anubadha ekadesham 1 shathamaanathilum biopsic sheshamulla maranam 0.20 sathamaanathilumaanu sambhavikkunnath. magnetic resonance imaging vazhi nayikkappedunna prostettu biopsy nadapadikramatthinte diagnostic krithyatha mechappeduthi.
prostettu-nirddishta aantijan.
prostettu grandhiyude epithelial koshangal sravikkunna prostettu-nirddishta aantijan (psa) rakthathinte oru saambilil kandethaam. aarogyamulla prostettukalulla purushanmaarude serathil pii. ezz. eiii cheria alavil kaanapedunnu, pakshe prostettu cancerinteyo mattu prostettu vaikalyangaludeyo saannidhyathil ithu palappozhum uyarunnu. prostettu kaansarinte savisheshamaaya soochakamalla psa, pakshe prostaattis allengil benin prostaattik hyperplasia kandethaanum kazhiyum.
2018 leeii yunaittad stetts preventive sarveesas task fozhsu (yuu. ezz. pii. ezz. tii. eph) karadu pii. ezz. eiii screeninginulla muun ethirppu krameekarichu. 55 num 69 num idayil praayamulla aarogyamulla purushanmaaril screening sambandhicha pankitta theerumaanamedukkal ithu nirddeshikkunnu. aaa praayathilullavarude anthima shupaarsha prakaram screening aagrahikkunnavarkk maathrame nadathaavoo. 70 vious athil kooduthalumullavaril screening shupaarsha cheyyappedunnilla.
amithamaya roganirnayam, anubandha doshangalodoppam vardhicha prostettu biopsy, vardhicha uthkanda, anaavashya chikitsa ennivayulppede niravadhi doshangalumaayi psa screening bandhappettirikkunnu. prostettu cancer parisodhanaye chuttipattiyulla thelivukal soochippikkunnathu ithu marananirakkil kaaryamaaya vyathyaasamundaakkilla ennaanu.
maruvashathu, 70kaliloo 80kaliloo polum roganirnayam nadathunna purushanmaaril 25 sathamaanam vare prostettu cancer baadhichu marikkunnu, "avarkk uyarnna grade undengil (athaayath.iii., aakramanathmaka) prostettu cancer. neremarichu, valare cheruppakkaaraaya purushanmarkkulla pii. ezz. eiii parishodhanaykkethire chilar vaadikkunnu, kaaranam oru cancer kandethaan valareyadhikam purushanmaare parishodhikkendathundu, koodaathe valareyadhikam purushanmaarkk purogamikkaattha cancerinu chikitsa undaayirikkum. kuranja apakadasaadyathayulla prostettu cancerinu ellaayppozhum udanadi chikitsa aavasyamilla, pakshe sajeevamaaya nireekshanatthinu ithu anuyojyamaayekkaam. oru pii. ezz. eiii parishodhanaykk prostettu kaansarinte asthithvam svayam 'theliyikkaan' kazhiyilla; aantijante vyathyastha alavukal mattu kaaranangalal aakam.
digital malashaya parisodhana.
oru digital malashaya parishodhanaykkide (dii. aarr. iii), oru aarogya parirakshaa daataav oru kaiyura viral malaashayathilekku slide cheyyukayum prostettil amarthukayum cheiyunnu, athinte valuppam parisodhikkaanum axus cheyyaavunna vashath enthengilum pindangal kandethaanum. parisodhanayil vairudhyangal undennu soochippikkukayaanenkil, oru pii. ezz. eiii parisodhana nadathunnu. uyarnna psa level kandethiyaal, thudarnnu oru fooloo-upp parisodhana nadathunnu.
praakteesinte falapraapthiyude thelivukalude abhavam kaaranam prostettu kaansarinulla praadhamika paricharana parishodhanaykkethire 2018 leeii oru avalokanam shupaarsha cheythu.
gunangalude thelivukalude abhavam kaaranam digital malashaya parisodhanaye oru screening upakaranamaayi yuu. ezz. pii. ezz. tii. eph shupaarsha cheiyunnu. prostettu cancer nirnnayikkaan deerghakaalamaayi drey upayogichirunnuvenkilum, eathu praayatthilum drey kandethumbol prostettu kaansarinte rogaavasthayo marananirakko kurayunnathaayi niyantritha padanangalonnum kaanichittilla.
55 num 69 num idayil praayamulla purushanmaarkk, aadya nira screening testaayi drey upayogikkunnathu thudarunnathinu thelivukalonnum kandethaan kazhinjillennu 2018 ll american eurological association prasthaavichu; ennirunnaalum, uyarnna psa ennu paraamarsikkunna purushanmaaril, drey oru upayogapradamaaya secondary testayirikkaam.
thudar parisodhanakal.
biopsy.
prostettu cancer kandethunnathinulla suvarnna nilavaaramaayi prostettu biopsykal kanakkaakkappedunnu. anubadha oru saadhyathayulla apakadamaanu. emm. aarr. aii guided teknikkukal nadapadikramatthinte diagnostic krithyatha mechappeduthi. malaashayathiloodeyo lingathiloodeyo biopsykal nadatthaam.
ultraasoundu.
traanstektal ultrasonography (truss) kku vegathayeriyathum kuranja aakramanathmakavumaaya gunamundu, koodaathe upariplavamaaya tumourinte moolyanirnayathinu emaaraiyekkaal mikachathaanu. ithu malaashayathinte mathilinte paalikalekkurichulla vishadaamshangalum nalkunnu, ithu praadhamika malashaya arbudam steju cheiyunnathinu krithyavum upayogapradavumaanu. praadeshikamaayi vikasippichathum stenosing cheiyunnathumaaya cancerukal drishyavalkkarikkunnathil emm. aarr. aii mikachathaanenkilum, perictal lymph nodukal steju cheiyunnathinu, truss, emm. aarr. aii ennivaykku kazhivundu. treasinu oru cheria kaazhchappaadaanenkilum 3dii treasinu anorectal rogangalude roganirnayam mechappeduthaan kazhiyum.
magnetic resonance imaging.
screening oru maarakathvam soochippikkumbol emm. aarr. aii upayogikkunnu. biopsy vilavu paramavadhi vardhippikkumbol eee model anaavashya prostettu biopsykal kuraykkaan saadhyathayund. emm. aarr. aii skaanukalude chelavinekkurichulla aashankakalkkidayilum, pii. ezz. eiii/truss biopsy adisthaanamaakkiyulla paricharanatthinte deerghakaala chelavu bharavumaayi thaarathamyappeduthumbol, imaging model chelavu kuranjathaanennu kandethi. munbu negatteevu biopsy nadatthiya rogikalkku emm. aarr. aii imaging upayogikkaam, pakshe avarude pii. ezz. eiii vardhichukondirikkunu. emm. aarr. aii. targettucheytha biopsy saankethikavidyakalil eathaanu kooduthal upayogapradamennu samavayam theerumaanichittilla.
mattoru chithram.
68gaa-psma pettu/sidi imaging thaarathamyena churungiya samayathinullil, eee imaging reethi labhyamaya klinikkal sentarukalil aavarthichulla prostettu cancer punasthaapikkunnathinulla swarnna nilavaaramaayi maari. idatharam muthal uyarnna apakadasaadyathayulla praadhamika prostettu kaansarinte ghattatthile staanderd imaging modalityaayi ithu marran saadhyathayund. therapy nayikkunnathinum kooduthal krithyamaaya prostaattik biopsy sugamamaakkunnathinumulla saadhyathakal paryavekshanam cheyyappedunnu. theranostic maathrkayil, 68 jii. eiii-pii. ezz. emm. eiii pettu/sidi imaging prostettu nirddishta membran aantijan-avid rogam kandethunnathinu nirnaayakamaan, athu targettucheytha 177luu-psma allengil 225essy-psma chikilsakalodu prathikarikkaam. praadeshika aavarthanathinu, 68 jii. eiii-pii. ezz. emm. eiii valarthumrigangal/emm. aarr. allengil valarthumrigangal/sidi enniva emm. pii. emm. aarumaayi samyojippikkunnath ettavum anuyojyamaanu. praadhamika prostettu paricharanatthinaayi multiparametric emri (emm. pii. emm. aarr. aii) yumayi samyojippikkumbol kyaansar kandethaan pii. ezz. emm. eiii pettu/sidi sahaayakamaayekkaam. chikilsaykku sesham praadhamika prostettu kaansarinte aavarthanam vilayiruthaan prostettu multiparametric emr imaging (emm. pii. emm. aarr. aii) sahayikkunnu.
matoraal.
prostettu kaansarinulla niravadhi biomarkerukal nilavilundu. ivayil ulppedunnu
korea instittyoott oof sayans aandu teknolajiyile (kist) gaveshakar swaabhaavikamaayi wide moothrathil ninnu biomarkerukalude alavu alakkaanulla kazhivulla oru moothra multy marker sensor vikasippicheduthu. moothra multy markerukal roopeekarikkunna sensing signalukalumaayi klinikkal avasthayude parasparabandham random phoorast, neural network ennee rund mesheen laining algorithangal vishakalanam cheythu. biomarkerukalude ennam vardhichathode rund algorithangalum screening prakadanatthil ekathaanamaaya vardhanavu nalki. biomarkerukalude mikacha samyojanathiloode, prostettu cancer rogikale 99 sathamaanathiladhikam krithyathayode parisodhikkaan algorithangalkku kazhinju.
tharkkam.
prostettu kaansarinulla parisodhana chikilsakarkkum vishalamaaya prekshakarkkumidayil charchakal srishtikkunnathu thudarunnu. sarkkar, sarkkarithara, medical samghadanakal rachicha prasidheekaranangal charcha thudarukayum parishodhanaykkulla shupaarshakal prasidheekarikkukayum cheiyunnu. aarr purushanmaaril oraalkk avarude jeevithakaalathu prostettu cancer undennu kandethumenkilum screening prostettu kaansarinte amithamaya roganirnayathinum amita chikilsaykkum kaaranamaayekkam. prostettu cancer moolamulla marananirakk kurayunnathu thudarukayaanenkilum, 2013ll amerikkayil 238,590 purushanmaarkk prostettu cancer undennu kandethukayum athinte falamaayi 29,720 perr marikkukayum cheythu. prostettu cancer moolamulla marananirakk 1992 muthal sthiramaaya thothil kuranju. 2013 ll american purushanmaaril puthuthayi kandethiya ellah kaansarukalilum prostettu, shwaasakosham, broncus, vankudal cancerukal enniva 50 shathamaanamaayirunnu, prostettu cancer 28 shathamaanamaayirunnu. prostettu kaansarinulla screening oro samsthaanathinum vyathyaasappedunnu, ithu prostettu kaansarinulla screening upayogathile vyathyaasangalum lokkeshanukal thammilulla vyathyaasangalum soochippikkunnu. prostettu kaansarinte ellah kesukalilum aafrikkan american purushanmaarkk 62 sathamaanam kesukalundu. aafrikkan american purushanmaarkk prostettu cancerinu staanderd therapy labhikkanulla saadhyatha kuravaanu. eee poruthakkedukal soochippikkunnathu avarkk uyarnna nilavaaramulla cancer chikitsa labhikkukayaanenkil avarude athijeevana nirakk vellakkaarkk samanamaayirikkum ennaanu.
prostettu cancer valare vaividyamaarnnathaanu mikka prostettu kaansarukalum alasathayullavayaan, oru purushante jeevithakaalathu roganirnayam nadathaathirikkukayum chikilsikkaathirikkukayum cheythaal orikkalum vaidyashaasthraparamaayi ardhavathaaya ghattathilekku purogamikkilla. maruvashathu, oru upavibhagam maarakamaayekkaam, rogashanthikkulla avasarathinte oru jaalakathinullil screening ivayil chilath thirichariyaan kazhiyum. athinaal, apakadasaadhyatha kuranja rogathe kandethiyaal palappozhum chikitsa aavasyamillennum sajeevamaaya nireekshanatthinu anuyojyamaakumennum manassilakki, "uyarnna apakadasaadyathayulla", marakamaaya prostettu cancer kandethunnathinulla oru maargamaayi psa screening chilar vaadikkunnu.
prostettu kaansarinulla parisodhana chelavukalum rogikalkku anischithamaaya deerghakaala nettangalum kaaranam vivaadamaanu. horren thante pusthakatthil aaa vikaaram prathidhwanikkunnu. maayo clinic polulla swakaarya medical sthaapanangalum "aaraan pii. ezz. eiii screening testt nadathendathu, aaraan vendathu ennathinekkurichulla shupaarshakalil samghadanakal vyathyaasappettirikkunnu" ennu amgeekarikkunnu. avar nigamanam cheiyunnu "aathyanthikamayi, ningal oru pii. ezz. eiii parisodhana nadathanamo ennathu ningalude apakadasaadhyatha gadakangal pariganikkukayum ningalude vyakthiparamaaya mungananakal vilayiruthukayum cheytha sesham ningalude doktarumaayi charcha cheytha sesham ningal theerumaanikkenda onnaanu."
2009ll europil nadatthiya oru padanatthil marananirakkil cheria kuravundaayi, oru jeevan rakshikkaan 48 purushanmaarkk chikitsa nalkendathundennu nigamanam cheythu. ennaal chikilsikkappetta 47 purushanmaaril mikkavarkkum veendum laingikamaayi pravartthikkaan kazhiyilla, koodaathe kooduthal thavana baathroomil pokendivarum. american eurological association parisodhanaye pinthunaykkunnathupole mayakkumarunnu kambanikalude screening testtukalude aakramanathmaka vipananavum vivaadangal srishtichittundu.
2011-ll oru niroopakan nireekshichathu "biopsy, cancer chikitsa enniva kaalakramena kaaryamaaya psa mattangal ullavarkko allengil klinikkal prakadanangalullavarkku udanadi therapy nirbandhamaakkunnavarko maathramaayi orotta psa nirnnayathe adisthaanamaayi upayogikkunnathu vivekapoornamaanu... psaude samboornna nilakal apoorvvamaayi maathrame ardhavathaakoo; kaalakramena psa nilakalile aapekshika maattamaan ulkkaazhcha nalkunnathu, pakshe chikitsa aavasyamulla oru cancer avasthayude krithyamaaya thelivalla."
charithram.
1990kalil pii. ezz. eyude screening aarambhichu. 1990 kalude thudakkathil aarambhicha prostettu kaansarinulla (err. ezz. pii. sii) screening sambandhicha europian kramarahithamaya padanatthil, pii. ezz. eiii adisthaanamaakkiyulla screening prostettu canceril ninnulla marananirakk kurachuvenkilum amita roganirnayathinulla uyarnna apakadasaadhyatha srishtichuvennu gaveshakar nigamanam cheythu.iii.onpathu varshathinullil prostettu cancer moolam oru maranam maathram thadayaan 1410 purushanmaare parishodhikkendathundu, koodaathe 48 adhika prostettu cancer kesukal chikilsikkendathundu.
europian jenal oof canceril (october 2009) prasidheekaricha oru padanatthil prostettu cancer parisodhana prostettu cancer marananirakk 37 sathamaanam kurachathaayi rekhappeduthiyittundu. psa screening apoorvamaaya vadakkan irelandil ninnulla purushanmaarude oru niyanthrana groupine upayogichukondu, erspc padanatthinte bhaagamaayi psa pareekshicha purushanmarumaayi thaarathamyappeduthumbol prostettu cancer maranangalil ganyamaaya kuravundennu gaveshanam kaanichu.
2009ll nyoo englandu jenal oof medisinil prasidheekaricha oru padanatthil 7 muthal 10 varsham vare "screening 55 vious athil kooduthalumulla purushanmaarude marananirakk kurachilla" ennu kandethi."stanford sarvakalashaalayil ninnulla chilar ulppede muun screening vakthaakkal pathiv parishodhanaykkethire ramgathethiyittundu. 2010 februvariyil american cancer sosaitti "parisodhana upayogikkumbol kooduthal jagrata palikkuka" ennu abhyarthichu."american koleju oof preventive medisin" pathiv screening shupaarsha cheiyunnathinu mathiyaya thelivukalillennu nigamanam cheythu."
cancerinum chikilsaykkum (pariraksha) padanathinumulla prostettu parisodhanayude bhaagamaayi, enhs thaarathamya vibhaagam (cap) enna mattoru patanam, brittanile 9 nagarangalile kendrangalil 2001-2005 muthal saadhaarana paricharanam allengil psa (biopsy psa ≤3 aanenkil) upayogichu prostettu cancer screening vare 460,000 purushanmarumaayi kramarahithamaya jipi reethikal. 2018 nte thudakkathil "thaarathamya vibhaagam" ithuvare report cheythitilla.

