
poost synaptic saandrata

poost synaptic membranumaayi bandhippichirikkunna protein saandramaaya "specialisationaan" poost synaptic density (psd). poost synaptic neuroninte membranile electron saandramaaya pradesamaayaanu electron microscopy psdkale aadyam thiricharinjathu. psd presignaptic active sonumaayi aduthunilkkunnu, koodaathe resepterukal presignaptic neuro traansmittar release sittukalumaayi aduthunilkkunnuvennu urappaakkunnu. thalachorinte pradeshangalkkidayil valippathilum ghadanayilum psdkal vyathyaasappedunnu, glutamaterjic sinaapsukalil ithu valare vishadamaayi padikkappettittund. glutamate resepterukal, scarfold proteinukal, niravadhi signalling thanmathrakal ennivayulppede poost synaptic saandrathayil noorukanakkinu proteinukal thiricharinjittundu.
ghadana.
padanathinteyum oormmayudeyum sellular modalaaya synaptic plaastitti sambandhicha niravadhi tanmatra padanangalude kendrabinduvaanu psdude ghadanayum ghadanayum. sinaapsinte pravartthanaavasthaye aashrayich 250 muthal 500 naanomeettar vare vyaasavum 25 muthal 50 naanomeettar vare kanavumulla kramathilaanu psdkal valuppathilullath. synaptic plaastitti samayat, single sinaapsukalil deerghakaala pottenshyeshan prerippichathinu sesham synaptic valuppathilum shakthiyilum vardhanavinoppam psdude motham valupavum vardhikkunnu.
rachana.
psdyile niravadhi proteinukal synaptic pravartthanatthinte niyanthranatthil earppettirikkunnu. iva ulppedunnu
maas spectrometry saankethikavidyakal mechappeduthunnathiloodu protein kandethal saankethikavidyakal samvedanakshamatha vardhippichathinaal, kooduthal proteinukal psdic kaaranamaayittund. nilavile kanakkukal prakaram thalachorinte pradeshangalkkidayilum vikasanathinteyum synaptic pravartthanatthinteyum vividha avasthakalilum psdkalil noorukanakkinu proteinukal kaanapedunnu. psdkalil koshangalude ottikkal thanmaathrakalum mattu signalling proteinukalude vaividhyamaarnna koottavum adangiyirikkunnu. pala psd proteinukalilum pii. dii. isad domainukal adangiyirikkunnu.
pravartthanam.
synaptic pilarppil neuro traansmittar resepterukal kendreekarikkaanum krameekarikkaanum psd nirddeshichittundu. psd oru signalling upakaranamaayum pravartthikkunnu. udaaharanathinu, psdyile kainesukalum phosphataseukalum sajeevamaakkukayum psdyil ninnu puranthallappedukayum nattellil sthithicheyyunna proteinukalude pravartthanam maattukayo protein sinthasisine baadhikkunnathinaayi nucleusilekku kondupookukayoo cheiyunnu. psdude chila savisheshathakal neuro muscular junction mattu sellular jangshanukalum poleyaanu, kaaranam psd vegameriyathum asamathvamullathumaaya signalling anuvadikkunna oru prathyeka sellular jangshanaayi maathrkayaakkappettundu.

