aspaarttett-semialdehyde dehydrogenase

ensimologyil, prokkariyottukal, fangasukal, chila uyarnna sasyangal ennivayile amino aasidukalude jaivasamshleshanathil valare pradhanappetta oru ensaimaanu aspaarttett-semialdehyde dehydrogenase (). ithu upapachayam vazhiyil oru aadyakaala shaakha pooyint roopappeduthunnu, ithu aspaarttettil ninnu lysine, methionin, lucine, isolucin enniva roopappeduthunnu. eee paatha bacteria koshabhithi roopeekaranathil pradhana punk vahikkunna diaminopimelate uthppaadippikkukayum cheiyunnu. eee ensaimine pravarthanarahithamaakkunnathu jeevajalathinu maarakamaanennu theliyikkunnathinaal athine thadayaan lakshyamitulla oru puthiya tharam antibioticukal, fungasideukal, kalanaashinikal ennivaykkulla saadhyathaykk kaaranamakunnathinaal asadil prathyeka thaalpparyamund.
eee ensime reversible raasapravarthanathe uthejippikkunnu
eee ensaiminte 3 substrateukal-aspaarttett 4-semialdehyde, phoosphett, naad pii + ennivayaanu, athesamayam athinte 3 uthppannangal-4-aspartile phoosphett, naduff, echu + ennivayaanu.
ennirunnaalum, shaareerika saahacharyangalil prathikaranam vipareeta dishayilaanu.
eee ensime ooksidooredaktesukalude kudumbatthil pedunnu, prathyekichu oru daathaavinte aldehyde allengil oakso groupil pravartthikkunnava, koodaathe naad + allengil naad pii + sweekarikkunnavayaanu. eee ensime klaasinte chittayaya peru-aspaarttett-4-semialdehydae naad pii + oxidoreductase (phosphorylating) ennaanu. saadhaaranayaayi upayogikkunna mattu perukalil aspaarttett semieldehyde dehydrogenase, aspartic semieldehyde dehydrogenase,-aspaarttett-beetaa-semialdehydae naad + oxidoreductase, (phosphorylating), aspartic beetaa-semieldehyde dehydrogenase, aasaa dehydrogenase enniva ulppedunnu. eee ensime glycine, serin, thrionin metabolism, lysine biosynthesis ennivayil pankedukkunnu.
chila isd jeenukalude 5 'yudiaaril kaanapedunna oru isd rna rooparekhayaal aspaarttett-semialdehyde dehydrogenase sis-niyanthrithamaayekkaam.
protein kudumbangal.
eee domainil arjinain biosynthesisil ulppedunna "enn"-asattail-glutamine semieldehyde dehydrogenase (eiii. jii. aarr. sii), aspaarttettil ninnulla vividha amino aasidukalude biosynthesisil ulppedunna aaspaartett-semieldehyde dehydrogenase ennee ensimeukal adangiyirikkunnu. ithil yeest, fungus aarji 56 protein ennivayum adangiyirikkunnu, ithu enn-asattail-gaama-glutamile-phoosphett reductase, asattailgloottaamett kinace ennee ensaimukalaayi vibhajikkappedunnu. iva arjinin jaivasamshleshanathilum ulppedunnu. eee entriyile ellah proteinukalilum semieldehyde dehydrogenesinte dimerisation domaine adangiyirikkunnu.
gadanaaparamaaya padanangal.
2007 avasaanathode, eee klaas ensaimukalkkaayi 24 gadanakal pariharichu, pii. dii. bii accession kodukal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

