
donald ell. vila

donald ell. vila (jananam sii. 1935) oru american neuro paatholajistum connectikkattile staamfordil janicha johns hopkins school oof medisinil professorumaanu. neuro degenerative rogangalude, prathyekichu alshimezhs rogathinte tanmatra adisthaanam manasilaakkaanaan addehathinte gaveshanam lakshyamidunnathu. addehathinte pravarthanangalkku niravadhi avaardukal nediyittulla prais american association oof neuro paatholajisttinteyum sosaitti phoor neuro sayansinteyum presidentaayi sevanamanushtichittundu.
aadyakaala jeevitam.
weslian sarvakalashaalayil chernna prisinu avide ninnu engleesh saahithyathil baachilar oof arts labhichu. 1961ll union sarvakalaashaalayile albani medical collegil ninnu birudam nediya addeham avide ninnu medical birudam nedi. union yooniversittiyile albani medical schoolil ninnu birudam nediya sesham, doow. prais oru medical inten, nyoo englandu medical sentar, boosttan, maa (1961-1963) ll thaamasakkaaranaayirunnu, koodaathe maas general hospital, boosttan, maa (1963-1968) yill neurology residency poortthiyaakki. addeham deseeya naavika medical sentar, bethesda, emm. dii. (<aii. dii. 1>) yill staaf neurologistaayirunnu. maas generalil (1968-1969) neuropathilajiyil seeniyar fello aayum harward sarvakalashaalayil sell/molecular biologyil (keeth porter) (1969-1970) research fello aayum addeham bostanilekku madangi. anhvichalpweb|url = HTTP:// pathology.juu.edu/vakupp/priserserch fund.pii. dii. eph|thalakkett = donald ell. vila gaveshana fund|theeyathi = meyy 18,2008|websait = johns hopkins medisin}} </repha>
currier.
1970ll harward medical skoolile neurology, pathology vakuppukalil asisttant professoraayirunnu praisinte aadya faakkaltti niyamanam. 
1971ll johns hopkins school oof medisinil prisine niyamichu, neuro pathology divishante sthaapaka director. 
nilavil johns hopkins school oof medisinil pathology, neurology, neuro sayans ennivayude professoraanu prais.
 american association oof neuro paatholajisttinte presidentaayi prais sevanamanushtichu.)) 1989-1990) ennathil ninnu 2000-2001 ennathil ninnu addeham neuro sayans sosaittiyude presidentaayi sevanamanushtichu.
prais instittyoott oof medisinil (naashanal akkadami oof sciences) amgamaanu (1998) 
kazhinja naalu pathittaandukalaayi noorukanakkinu medical, biruda vidyaarthikalkkum house offeesarmaarkkum poost doctoral fellomark addeham pariseelanam nalkiyittundu. adhehathinteyum munkaala parisheelakarudeyum keezhil vakuppukalude chairpersonukalum vividha sthaapanangalile (medical schoolukal, sarvakalashaalakal, sarkkar) niravadhi pramukha adisthaana shaasthranjarum klinishyanmaarum ulppedunnu, eee vyakthikalil bhooribhaagavum vaidyashaasthrathilum/allengil shaasthrathilum sajeevamaayi thudarunnu. 
masthishkathinte dashakathil" (1990-2000), sayans vaachu (12 102 2001) neuro sayansile hye impact pepparukalude rachayithakkalaayi prais mikacha patthu neuro sayantistukalil ulppettirunnu.>
gaveshanam.
motor neuronukalude jeevashaasthrathil aadyam shradha kendreekarichu, ennaal pinneedu addehathinte kariyaril mastishka samvidaanangalil kooduthal thaalpparyamundaayi. manushya maathrkakal upayogikkunnathinekkaal "rogakaarikalekkurichu kooduthal nerittulla ulkkaazhcha anuvadikkunnathinu" addeham pradhaanamaayum mruga maathrkakal upayogichu. addehathinte prathyeka gaveshana thalpparyangalil "praayavumaayi bandhapetta neuro degenerative rogangal, prathyekichu [alsheimer rogam]" ulppedunnu. echu. 1985ll addeham johns hopkins sarvakalaashaalayile alsheimers disease research sentarinte pradhana anweshakanaayi. oduvil addeham kendratthinte director, ippol emeritus director.
alshaimezhs rogam.
neuro degenerative avasthakalkkulla chikilsayil praisinte gaveshanam shradha kendreekarikkunnu. transgenic elikal manushyarilekku athunnathinumumbu puthiya chikitsa samvidaanangal pareekshanaathmakamaayi pareekshikkaan transgenic elikalkkaayulla addehathinte pravartthanam shramikkunnu. eee padanangal palappozhum apakadasaadyathayulla gadakangalaaya nirddishta jeenukale, prathyekichu amyloid-saadhyathayulla jeenukale thirichariyukayum avaye alsheimer rogavumaayi bandhapetta prathyeka perumattangalumaayi bandhappedutthaan sramikkukayum cheythu. udaaharanathinu, amyloid precursor proteinukalilekkulla mutationukal oormma nashtavumaayi bandhappettirikkunnave addehathinte gaveshanam nigamanam cheythittundu. adisthaana neurochemistry molecular, sellular, medical neurobiology thathwangal" enna paatatthinte prasidheekaranathil prais pankedutthu. sahapravarthakaraaya philipp sii. yumayi addeham pravarthichu. alshimezhs rogathekkurichum athu thalachorinullil engane valia vaikalyangal undaakkunnu ennathinekkurichum oru adhyayam ezhuthaan vongum tong liyum. vilayil ettavum kooduthal gaveshanam cheyyappedunna vishayangalilonnaan alsheimer rogam (parasyam). neuronal nashtam, pravarthanakshamamaaya neuronukalude parajayam allengil thalachorinte chila bhagangalkkullil neurofibrillary tanglesinte (enn. eph. tii) abhavam ennivayaanu parasyatthinte neuro sayansinte savisheshathayennu vila kandethi. neurofibrillary taamgilukalekkurichum avaa central superior nucleusil engane saadhaaranayaayi kaanapedunnu ennathinekkurichum addeham prasidheekaranathil charcha cheythu. rogathinte dairkhyam nirnnayikkaanum enn. eph. tii. ezz sahaayikkunnuvenn addeham vivarichu. parasyatthinte dairkhyam kurravulla rogikale apekshichu parasyatthinte dairkhyam kooduthalulla rogikalkku kuranja enn. eph. tii. kall maathrame undaayirunnulloo. nucleusukalile enn. eph. tii. kalude ennam purogathiyude nirakkine vipareethamaayi prathifalippikkunnu; enn. eph. tii. kalude oru cheria ennam maathrame kandethiyittulloovel, rogam pathukke purogamikkunnu.
prasidheekaranangal.
addehathinte ettavum udharicha prasidheekaranangalil chilath chuvadeyulla pattikayilaann

