
roow 64-6198

shaasthreeya gaveshanathil upayogikkunna oru nosiseptoid marunnaan roow 64-6198. mattu opioid resepterukalekkaal 100 madangu thiranjedukkunna oorl-1 (opiyettu risapttar like-1) risapttar ennum ariyappedunna nosisepttin resepterinu ithu shakthavum selective agonistumaayi pravartthikkunnu. benzodiasepine marunnukalkk thulyamaaya mruga padanangalil ithu ansiolitic efakttukal srishtikkunnu, pakshe aanti konvalsant efakttukalonnumilla, perumaattatthil prathyakshamaaya phalangalonnum undakkunnilla. ennirunnaalum ithu hraswakaala oormmashakthiye thakararilaakkukayum sammarddathaal undaakunna anorexy prathirodhikkukayum cheiyunnu. ithinu antitusive efakttukalum undu, koodaathe morphinte prathiphaladaayakavum vedanasamhaariyumaaya efakttukal kuraykkunnu, ennirunnaalum ithu aashrithathvathinte vikaasathe thadanjilla. ithu mrugangalile madya svayam-bharanathe kuraykkukayum madyapaanathinte mruga maathrkakalil adichamarthappetta aavarthanangale kuraykkukayum cheiyumennu theliyikkappettittund, koodaathe oorl-1 agonistukalkku madyapaanathinte chikilsayil prayogam undayirikkaam.
mattu opioid risapttar ligandukalil ninnu vyathyasthamayi elikalkku oru discriminative stimulas aayi thirichariyaan roow 64-6198 nuu kazhinju, pakshe addictive pottensialine soochippikkunnuvennu karuthappedunna contition cheytha sthala munganana nirmmikkaan kazhinjilla. thalphalamaayi, shareerathile oorl-1 resepterukalude punk sankeernavum moshamaayi manassilakkappettathumaanum, roow 64-6198 onniladhikam pharmacological pravartthanangal prakadippikkukayum oorl-1 risapttar systethekkurichulla padanatthil valare upayogapradamaavukayum cheythu, prathyekichu uthkandayum anorexiayumaayi bandhappett; ennirunnaalum, mosham ooral bioavilability kaaranam, roow 64-6198 mikkavarum klinikkal aayi pinthudarilla. praimettukalile padanangal ithu vedanasamhaarikalaaya phalangal undaakkunnundengilum shwasana vishaadamo shakthippeduthunna phalangalo undaakkunnillenn kaanichu.

