saitokin signalling adichamarthal

jacq-staatt signalling paathaye thadayunnathil ulppedunna jeenukalude oru kudumbatheyaanu soaks (saitokin signalling proteinukalude suppressor) soochippikkunnathu.
ghadana.
ellah sokkukalkkum pothuvaaya chila gadanakalundu. protein-protein edapedalukalil ulppedunna vyathyasthamaaya enn-terminal domaine, tyrosine kainaasukal phosphorilettu cheytha thanmaathrakalumaayi bandhippikkaan kazhiyunna oru central central domaine, iii3 ligasukaludeyum ubiquitin signalling thanmaathrakaludeyum recruitment prapthamaakkunna sii-terminalil sthithicheyyunna oru socs boxes enniva ithil ulppedunnu.
kandethal.
saitokin signalinginte adichamarthal yanthramaayi tharamthiricha aadyathe proteinaaya sis (saitokin-indusible shhaa2) 1995 ll saitokin signal transduction niyantrikkaanulla savisheshamaaya kazhivullathayi kandethiyappol kandethi.
pravartthanam.
jacq-staatt signalling paathayude negatteevu regulatormaaraanu soaks. cytokainukal, valarchaa gadakangal, tumour adichamarthal ennivayude niyanthranatthilum sokkukal ulppettittund. 
rogathil punk.
ifanji, tnfa, ail-15 thudangiya rogaprathirodha koshangal sravikkunna proo-inflammatory cytokainukalude negatteevu niyanthranatthiloode pramehathile saitokin-mediated apoptosis thadayaan sokkukalkku kazhiyumennu nirddeshikkappettittund. oru prathyeka sokkukalude anuchithamaya pravartthanam, soaks 3 type 2 pramehathilekku nayichekkaam, kaaranam sariyaaya lepttin signalingil soaks 3 oru pradhana punk vahikkunnuvennu kandethiyittundu.

