
bii. kaar3

stanarbuda virudha eestrajan prathirodha protein 3 manushyaril "bii. sii. aarr. 3" jeane encode cheiyunna oru proteinaan.
pravartthanam.
sthanaarbudangal thudakkathil valarchaykkum purogathikkum eestrajanukale aasrayikkunnu, tamoxifen polulla aanti-eestrajanukalkku ithu thadayaan kazhiyum. ennirunnaalum, stanarbudam eestrajan virudha prathirodhasheshiyullathayi maarunnu. eestrajan prathirodham vikasippikkunnathil ulppedunna jeenukalkkaayulla thirachilil stanarbuda virudha eestrajan prathirodha jeane 3 kandethi. manushya stanarbuda koshangalil eestrajan-swatantra vyaapanathin kaaranamakunna intra sellular signal traansdakshante oru gadakathe jeane encode cheiyunnu. sellular tyrosine kainas signalling thanmaathrakalude mukhamudrayaaya oru anumana src homology 2 (eshh2) domaine proteinil adangiyirikkunnu, ithu sell division saikkil protein cdc48-nuu bhaagikamaayi thulyamaanu.