
aarr. enn. eiii. rooparekha

oru aarr. enn. eiii motif ennathu oru anubandha gadanayulla aarr. enn. ekalude oru koottatthinte vivaranamaan. rna roopangal bandhapetta aarenekalude praadhamika kramatthilum dvitheeya ghadanayilum savisheshathakalude oru paatten ulkkollunnu. angane, rna dvitheeya ghadana ulppeduthunnathinaayi ithu oru sequence motif enna ashayam vipuleekarikkunnu. rna motif" enna padam paattenineyum athumaayi poruthappedunna rna sequenceukaleyum soochippikkaan kazhiyum.
aarr. enn. eiii. roopakrithikal vivarikkunnu.
rna roopangal rund pradhana roopangalil vivarikkaam onniladhikam sequence vinyaasam allengil vyakthamaaya thirayal paatten. oru vinyaasam saadhaaranayaayi oru samavaaya dvitheeya ghadana upayogichu vardhippikkunnu, athaayath.iii. ellah allengil mikka aarenekalkkum pothuvaaya ghadana. vinyaasathile sequenceukal pinneedu rnaude adhika udaaharanagal kandethaan upayogikkaavunna samrakshanathinte oru paatten parokshamaayi nirvachikkunnu. eee thirayal thanthram nadappilaakkunnathu, mattullavaykkoppam, naraka software paakkejaan. 
vishwasaneeyamaayi ariyappedunna rna rooparekhakaludeyum anubandha vivarangaludeyum oru valia upavibhaagathe nirvachikkunna onniladhikam sequence alainmentukalude oru shekharamaanu rfam daattaabes. sequence daattabesukalil atharam aarenekalude udaaharanagal kandethaan athinte daatta naraka software upayogichu upayogikkaam, udha.jii. genome sequenceukal.
pakaramaayi, helikkukal evide roopappedanam ennathinte parimithikalumayi samyojippichu nirddishta praadhamika sequence paattenukal nirvachikkunna vyakthamaaya thirayal paattenukal upayogichu rna motifukal vivarikkaam. oru valia sequence daattaabesil poruthappedunna thudarchakal kandethaan atharam paattenukal upayogikkaam. niravadhi software paakkejukal atharam oru thirayal nadappilaakkunnu, udha.jii. runarobo runamotif.
aarr. enn. eiii. roopakrithikal kandupidichu.
puthiya rnakal kandethunnathinulla pala reethikalum oru thaarathamya sameepanam upayogikkunnu, athil oru samrakshitha rnaude swabhaavasavisheshathakal kandethunnathinayi vyathyastha sequenceukal orumichu vishakalanam cheiyunnu. atharam reethikal vijayakaramaakumbol, thathfalamaayundaakunna puthiya samrakshitha rna oru rna rooparekhayaayi kaanaan kazhiyum, ithu oru vinyaasamo paatten upayogicho prakadippikkunnu.
1993ll aminosyl-trina synthates jeenukalumaayi bandhappettathayi nirnnayicha tii-boxine adisthaanamaakkiyulla rna mottippaanu aadyakaala udaaharanam. eee rna roopakam jeenukale niyanthrikkunna samvidaanam pinneedu pradarshippikkukayum angane rna roopakathinte pravarthanaparamaaya praadhaanyam sthaapikkukayum cheythu. pinneedu, 1997-ll, bii12-boxes enna samrakshitha rna roopakam bii12 metabolisavumaayi bandhapetta jeenukalude mukalilekku kandethi. eee rna rooparekha pinneedu qoo-factor adenosylcobalamine bandhippikkunna oru riboswichinte oru bhagavumaayi poruthappedunnuvennu kandethi, ithine palappozhum cobalamin riboswich ennu vilikkunnu. (pilkkala vakabhedangal mattu cobalamin derivetteevukale bandhippikkunnathayi kaanichu.) pinneedu nirnnayicha pravartthanangalude aarr. enn. eiii roopakrithikalkku mattu niravadhi udaaharanagal ariyappedunnu, prathyekichu riboswichukalude pashchaathalatthil. ennirunnaalum, 2007 ll oru roopamaayi kandethukayum 2016 ll pravartthanaparamaayi avatharippikkukayum cheytha 6 sii rna polulla baakteeriyal sarnakal allengil rna roopamaayi kandethukayum athe prasidheekaranathil pravartthanaparamaayi avatharippikkukayum cheytha twisttar ribosime polulla ribosymeukal polulla mattu tharam rna roopangal pravartthanaparamaayi savisheshatha nalkiyittundu.

