
chiri 2eiii

manushyaril "grin2eiii" jeane encode cheiyunna oru proteinaan glutamate [enmdb] risapttar subunit epsiloon-1. 1464 amino aasidukalulla canonical gloon2eiii subunit isophome valuthaanu. praimettukalkku prathyekamaayi gloon2eiii-short isophomukal badal spliesing vazhi ulppaadippikkaan kazhiyum, koodaathe 1281 amino aasidukal adangiyirikkunnu.
pravartthanam.
ionotropic glutamate resepterukalude oru vibhagamaanu enn-methyl-dii-aspaarttett (nmda) resepterukal. chila tharatthilulla oormmaykkum padanatthinum adivarayidunnathaayi karuthappedunna synaptic traansmishante kaaryakshamathayile pravartthanatthe aasrayikkunna vardhanavaaya deerghakaala pottenshyeshanil enmda chaanal ulppedunnuvennu theliyikkappettittund. qee risapttar subunit nmdar1 (grin1), 4 enmdr2 sabyoonittukalil onno athiladhikamo nmdar2eiii (grin2eiii), enmdr2babaiii (grin2bii), enmdr2zaiii (grin2sii), enmdr2daaiii (grin2dii) enniva chernna hetaromarukalaanu nmda risapttar chaanalukal.
associationukal.
jeeninte vakabhedangal paarkkinsans rogathil kaappiyude samrakshana falavumaayi bandhappettirikkunnu.
grin2eiiiyile mutationukal refractory apasmaravumaayi bandhappettirikkunnu.
muzhuvan exome/genome sequencing, apasmaram, boudhika vaikalyam, oottisam spectrum disordezhs, vikasana kaalathamasam, schisophrenia ennivayulppede vaividhyamaarnna neurological rogangalum grin2eiiiyile mutationukalum thammilulla bandham kandethunnathilekku nayichu.
ashayavinimayam.
grin2eiii ithumaayi samvadikkunnathaayi kaanichittundu