
gertrude moudu robinson

sasya pigmentukalekkurichulla avarude pravarthanangalkku ettavum prashasthayaya oru swaadheenamulla jaiva rasathanthranjayaayirunnu gertrude moudu robinson (munbu walsh); avarude perilulla pailotti-robinson pyrol synthesis; phaatti aasidukalude synthesis; pensilin swabhaavamulla aadyathe synthetic thanmathrayaaya δ-hexenolectoninte synthesis.
jeevacharitram.
1886 februvari 6 nuu cheshayarile winsfordil janicha robinson 1954 march 1 nuu hridayaaghaatham moolam marichu. verdin secondary schoolil chernna sesham avarkk bii. eiii. birudam labhichu. ezz. sii. 1907-lum emm. ezz. sii. 1908ll ovens collegil ninnu. pinneedu israayelinte aadya presidentaaya cheyim weismante keezhil maanchastar sarvakalashaalayil gaveshanam nadatthiya avar maanchastar haiskoolil penkuttikalkaayulla rasathanthram padippichu.
1912-ll avar roobert robinsonine vivaham kazhichu, pinneedu 1947-leeii nobal sammanam nedukayum avarodoppam niravadhi prabandhangal rachikkukayum cheythu, kurachu samayathekku sent saintilekku pookunnathinumumbu sidney sarvakalashaalayil shambalamillaatha demonstrator sthaanathekku maari. landanile skotlandilum yooniversitti collegilum andruz. pooritha, aparyapthamaaya phaatti aasidukalude samanvayathil pravarthicha avar oliyik assid lactarinic assid aadyamaayi samanvayippichu. avarude reethikal akkaalathe ettavum valia tanmatra bharamullah (prathyekichu, trichontanoic, 13-oxodotetrakondanoyik aasidukal) phaatti aasidukalude samanvayathilekku nayichu.
sugandhamulla assoxy samyukthangalude asamamaya ghadana avar swathanthramaayi nirddeshikkukayum bharthavinoppam fisher indoll sinthasisinulla oru samvidaanam nirddeshikkukayum cheythu. eee samvidaanathe adisthaanamaakki pailottiyude pyrol synthesisukal pravarthippichukondu, dambathikal tetrafenylpyrol samanvayippikkunnathinu oru reethi nalki. pailotti-robinson pyrol synthesis avarude bahumaanaartham namakaranam cheyyappettittund.
ooksfoord sarvakalaashaalayilekk marria sesham, jertrude robinson sasya pigmentukal padikkaan thudangukayum bharthavinoppam anthosayaninsinekkurichu vipulamaayi prasidheekarikkukayum cheythu. oru chediyude pigmentinte niram athinte sravathinte piechumaayi bandhamillaathathaanennu aadyam nireekshicha avar leukoanthosayaaninukali pravarthanatthinu thudakkamittu. koodaathe, antibiotic gunangalulla pensilinu samanamaaya oru thanmathrayaaya δ-hexenolectone aadyamaayi samanvayippichathu avalaanu. 1953ll ooksfoord sarvakalashaala avarkk oonarari emm.eiii. birudam.
oru rasathanthranjayenna nilayilulla jolikkupurame, jertrude robinsoninu 1921-ll maariyon, 1926-ll maikkal enningane rund kuttikalundaayirunnu. avar oru parvathaarohakayum samriddhamaaya sanjaariyum pathivayi aathidheyayayayumaayirunnu. orupakshe sasya pigmentukalile pravarthanatthinu prachodanamaaya avalum bharthaavum varshangalolam oru poonthottavum sookshichu.
sasya janithakashasthram.
aanthosayaaninukalum koppigmentukalum.
pookkal, pazhangal, elakal ennivaykku avayude pigmentukal aanthosayaaninukalil ninnum kopigmentukalil ninnum (tannin, flavenolukal polullava) labhikkunnu. eee kombineshanukal vikasanathinte vividha ghattangalil vividha sasyangalude krithyamaaya nirangal nalkunnu. antosayanins koppigmentukalude vyathyastha anupaathangalil, koppigmentukalkk vyathyastha falangalundennu robinsons kandethi, ithu antosayanin complexukale thakarkkunna koppigmentukal moolamaanennu avar anumaanichu, avaa orumichu laayaniyil aayirikkumbol avar nireekshichu. kshaarangalumaayo ferric chlorideumaayo ulla prathikaranangalkk sesham kalarppillaatha laayanikalile varnnavitharanagal thaarathamyam cheythukondu avar eee pigmentukal padichu.
leucoanthosayanins.
mikka sasyangalilum kaanapedunna, anthosayaanidinukal ulppaadippikkunna niramillaatha thanmathrakalaaya leukoanthosayaninsin gadanayekkurichu robinsons anweshichu. rosenheim oresamayam leucoanthosayanins kandethukayum addeham eee padam srishtikkukayum cheythu. saadhaarana aanthosayaaninukalekkaal kooduthal sthalangalil (maram, puramtholi, cherunaarangakal, pookkal, pazhangal) leucoanthosayanins kaanapedunnu.
pailotti-robinson pyrol synthesis.
pailattiyude peril aadyam ariyapetta eee prathikaranatthinu, samvidaanathekkurichulla avarude pravartthanam kaaranam robinson enna peru chertthu. eathu robinson sinthasisaanu saankethikamaayi namakaranam cheythathennu vyakthamallengilum, eee vishayathekkurichulla prabandham ezhuthiyathu gertrude robert aanu.
saamaanyavalkkaricha synthesis.
asainukale 3,4-disbspituted pyrolukalaayi parivartthanam cheyyaan eee prathikaranam upayogikkunnu.
saamaanyavalkkaricha samvidaanam.
robinsons nirddeshichathupole samvidaanam.
ennirunnaalum, chila sinthasisukalil chila prashnangalund. pyrotti-robinson prathikaranam pyrasolinte roopeekaranavumaayi malsarikkunnu, appol riyaaktant oru kettonil ninnu uruthirinja oru aliphatic assain aanu. koodaathe, uyarnna thapanilayilum uyarnna acidity laayanikalilum aldehydeukalil ninnu uruthirinja asainukal sthirathayullavayalla. eee reethi upayogichu 2,5-disbspituted pyrolukalude (ivide r = h) roopeekaranam ithu thadayunnu.
aadhunika upayogangal.
pailotti-robinson synthesis uthppaadippikkunna pyrolukal palappozhum valare upayogapradamaanengilum, mukalil soochippicha prashnangalkk purame uyarnna thapanilayum neenda prathikarana samayavum aavasyamullathinaal prathikaranam ellaayppozhum anukoolamalla, vilavu palappozhum kuravo mithamo aanu. aadhunika reethikal eee aashankakalil chilath laghookarichittundu.
microwave vikiranangal.
microwave vikiranam prathikaranatthinu aavashyamaaya samayam ekadesham 3 divasathil ninnu 30-60 minittayi kuraykkunnu. ithu vilavu kuraykkaanum saadhyathayund.
sakthamaaya pinthuna.
khara-pinthunayulla synthesisukal eluppavum kooduthal kaaryakshamavumaya varkkapum shudheekaranavum vaagdaanam cheiyunnu.
fisher indoll samvidaanam.
pii-toluidine polulla mattu sugandha aminukalude saannidhyathil prathikaranam thadassamillaathe nadannuvennu kaanichu fisher indoll samvidaanathekkurichulla nilavilulla pala sidhaanthangalum robinsons nishedhichu. ithaanu avar nirddeshicha samvidaanam (ivide hydrajan shifttukale aasidile hydrajan ekschenchukalaayum vyaakhyaanikkaam).
poorithavum aparyapthavumaaya phaatti aasidukal.
uyarnna phaatti aasidukalude samanvaya reethikal.
phaatti aasidukalude samanvayathinulla robinsons reethikalude poraaymakalilonnu dialdehydinte ganyamaaya bhagam veendedukkunnathu moolamulla kuranja vilavaanu. eee kuranja vilavinu jertrude robinson nalkia nyaayeekaranam aldehyde intermediat asattik aasidinekkaal durbalamaaya aasidaayirunnu ennathaanu, ithu jalavishleshanathinte oru ghattathil neekkam cheythu. eee prashnam avar pariharichillenkilum, "saadhyamaaya ettavum durbalamaaya aasidumaayi bandhapetta group pakaram vacha ethyl asetto asattett assilation" vazhi avar vilavu mechappeduthukayum veendedutha dialdehyde kuraykkukayum cheythu.
13-dichetopalmitic assid vazhi 10-kettotridecoic aasidinte samanvayamaanu ithinte oru udaaharanam, ithu oru pradhana aasidaan, kaaranam, kurravinum nirjjaleekaranathinum sesham, ithu sajeevamaaya andashaya hormon thanmaathrayaayi maarunnu.
uyarnna phaatti aasidukalude samanvayathinaayi jertrude robinson, melisic assid ennum ariyappedunna enn-triacontanoic assid, 13-oxodotetrakondanoyik assid enniva samanvayippichu.
oleeku assid.
robinsons erattabandhathinte sthaanam thirichariyukayum oleeku assid samanvayippikkukayum cheythu.
robinsansinte oliyik aasidinte synthesis
lactarinic assid.
lactarius janussile fangasukalil ninnu verthirichedutha lactarinic aasidil oru kettostiyarik assid adangiyittundennu kaanichu. lactarinic aasidinte ooksaimil beckman parivartthanam cheythukondu ithu yadhaarthathil 6-kettostiyarik aasidaanenn robinsons kaanichu. ethyl sodio-2-asattail-enn-tridecoat, 5-carbethoxyvaleril chloride ennivayude prathikaranatthiloode avar 6-kettostiyarik assid samanvayippikkukayum thudarnnu lactarinic aasidinte ghadana theliyikkaan jalavishleshanam nadathukayum cheythu.