
sachari blound

sachari dii. iii. yude panthrand janasamkhyakalilonnil sitrettile aerobic valarcha enna pradhana naveekaranatthinte parinaamathekkurichulla pravarthanatthinu peruketta oru american parinaama jeevashaasthranjanaanu blound. koolii "deerghakaala parinaama pareekshanam. mishigan stettu yooniversittiyil richard lenskikkoppam jolie cheiyunna research asisttant professoraanu blound. munbu lenskyude poost doctoral research asisttantaayirunna addeham 2018 muthal 2019 vare keniyan collegil bayolajiyude visitting asisttant professoraayirunnu.
aadyakaala jeevithavum vidyaabhyaasavum.
sachari dii. jorjiyayilaanu blound janichathum valarnnathum avide addehathinu shaasthrathil aadyakaala thaalparyam valarnnu. jorjia instittyoott oof teknolajiyil ninnu jeevashaasthrathil uyarnna bahumathikal nediya addeham avide professor emeritus thomas tornabean addehathe microbiologyilekku parichayappedutthi. sinsinnatti sarvakalashaalayil ninnu birudaananthara birudam nediya addeham dennis grogante maarganirdeshaprakaaram "sulfolobus" janussile hyperthermo acedophilic aarkkiyayude insersion sequence gadakangalil pravarthichu. richard lenskiotoppamulla doctoral jolikkayi 2003ll addeham mishigan stettu yooniversittiyilekku maari.
gaveshanam.
2003ll, richard lensky 15 varshavum 33,000 thalamurakalum deerghakaala parinaama pareekshanam aarambhichu, ithu "iii" yude oru vamshamaan.koolii "valare uyarnna malinatha kaanikkan thudangi. poost doctoral gaveshakayaaya kristeena borland nadatthiya padanangal kaanikkunnath eee uyarnna malineekaranam malineekaranam moolamallennu kaanikkukayum janasamkhyayil sitrettile aerobic valarcha swamedhayaa vikasichathayi sthireekarikkukayum cheythu. blaant "parinaamathmaka replay pareekshanangalude" oru parambara nadatthi, athil aerobic sitrettu upayogam vyathyastha samaya pooyintukalil ninnu verthirichedutha vyathyastha clonel genodypeukalil ninnu parinamicha janasamkhyayude parinamam punarnirmmikkukayum sii. tii + lake parivartthanam cheyyaanulla pravanatha engane maariyenn parisodhikkukayum cheythu. eee vishakalanathil niravadhi trilyan bacteria koshangalude parisodhana ulppedunnu, pilkkala thalamurakalil ninnulla klonukal sii. aii. tii + lekkulla parivartthana nirakk ganyamaayi vardhippichuvennu kaanikkunnu, ithu janasamkhyayile swabhaavathinte parinamam "shakthiyeriya" mutationukal shekharicha charithrathe aashrayichirunnuvenn soochippikkunnu, athu mutationally axus cheyyaan kazhiyum. janasamkhyayil ninnulla klonukalude janithaka vishakalanam pinneedu sii. tii + swabhaavathinte udanadi janithakavum biochemical adisthaanavum oru tandom duplication mutationaayi sthaapichu, athu oru puthiya promoterude niyanthranatthil oru nishabda sitrettu transporter jeenine sthaapichu, ithu ooksijan ullappol athinte aavishkaarathin kaaranamaayi, promoter capturinteyum jeane eksaapteshanteyum oru udaaharanamaanu. eee kandethalukalude adisthaanathil, sankeernamaaya swabhaavasavisheshathakalude parinaamathinaayi blound oru maathruka nirddeshichu 1. savisheshatha parinamaparamaayi axus cheyyaavunna mutationukal shekharikkunna pottenshyeshan, 2. oru mutation oru phenotypic switch srishtikkunna yaadhaarthyavalkkaranam, athil puthiya swabhaavam prakadamaakunnu, 3. prakrithinirnnayam thudarnnulla mutationukal shekharikkunna parishkkaranam, puthiya swabhaavathe kooduthal phalapradamaakkunnu.
nilavil, sankeernamaaya swabhaavasavisheshathakal engane parinamikkunnu, puthiya swabhaavasavisheshathakal paristhithiye engane swaadheenikkunnu, weslian sarvakalaashaalayile frederic kohan nirddeshicha modalukale adisthaanamaakki alaingika janasamkhyayil speeshiyeshan engane sambhavikkunnu ennathinekkurichu blound kooduthal anweshikkunnu.

