
melanosite-inhibitting ghadakam

auxitosin hormon pilarppil ninnu uruthirinjathum ennaal shareerathil saadhaaranayaayi vyathyastha pravarthanangalullathumaaya oru endogenous pepttaid sakalamaanu melanosite-inhibitting factor (proo-liu-gly-enh 2, melanostaattin, emhs release-inhibitting hormon allengil imf-1 ennum ariyappedunnu). miff-1 onniladhikam efakttukal srishtikkunnu, ithu opioid risapttar aakttiveshante phalangale thadayunnu, athesamayam dii 2, dii 4 dopamine risapttar upavibhaagangalude positteev alosteric modulettaraayi pravartthikkunnu, athupole thanne alfa-emsh polulla mattu neuropeptaidukalude prakashanam thadayunnu, koodaathe melattonin pravartthanatthe shakthippeduthunnu.
eee sankeernamaaya pravartthanangalude misritham miff-1 nalkumbol aantidiprasant, nootropic, aanti-parkinsonian efakttukalude oru profile srishtikkunnu, ithu vividha medical upayogangalkkayi anweshikkappettittund. rakthapravaahathile mettabolisathe asaadhaaranamaayi prathirodhikkunna miff-1, vaayiloode valare sajeevamallathathum saadhaaranayaayi kuthivaykkunnathumaane, raktha-mastishka thadassam eluppathil marikadakkunnu. shareerathile pradhana pravarthanangalumaayi adutha bandhamullah mattu niravadhi pepttaidukalil tyre-miff-1, endomorphine-1,-2 enniva ulppedunnu.

