
klaas II jeane

oru proteine coode cheiyunna oru tharam jeenaanu klaas II jeane. klaas II jeenukal aarr. enn. eiii. pii II aanu traanskript cheiyunnathu.
klaas II jeenukalkku oru taatta boxes adangiyirikkaavunna oru promoter undu.
klaas II jeenukalude adisthaana transcription oru preinitiation complexinte roopeekaranam aavasyamaanu.
avaa rna polymerase II transcribe cheythirikkunnu, intron exone ulppedunnu, koodaathe polypeptidinulla code ulppedunnu.
rogaprathirodha prathikaranatthil pradhana histocompattibilit complexes (emechsi) klaas II jeenukal pradhaanamaan.
aantijan-presenting cellukalil (eiii. pii. sii.) kaanapedunna pradhana histocompattibilit complexes (emm. echu. sii) II, sidi4 + tii cellukalilekku exogenous proteinukal avatharippikkunnathin pravartthikkunnu. sii. dii. 4 + tii. koshangalude sajeevamaakkaliloode extra sellular rogakaarikalodu prathikarikkunnathil rogaprathirodha samvidaanathe sajeevamakkunnathil emm. echu. sii. II oru pradhana punk vahikkunnu. emm. echu. sii klaas II thanmathrakal onniladhikam kosha tharangalil vyathyasthamayi prakadippikkunnu. udaaharanathinu, emm. echu. sii. II thanmathrakal thymic epithelial koshangalilum aantijan-presentering cellukalilum (eiii. pii. sii. kall) gadanaaparamaayi prakadippikkappedunnu, athesamayam avaa mattu kosha tharangalil interferon-jii. emm-mediated expression vidheyamaakunnu. emm. echu. sii klaas II thanmathrakal pradarshippikkunna sankeernamaaya jeane-expression profilinte niyanthranatthinte kendrabindu klaas II traansaaktivettar (siaidi) ennariyappedunna orotta maasttar regulatory gadakamaanu. moonnu swatantra promotermaar (paii, paii, piv) adangunna oru regulatory mekhala karsanamaayi niyanthrikkunna dna-allatha oru qoo-aaktivettaraanu sietta.