
synthetic antibody

synthetic aantibodikal poornnamaayum inn vitroyil uthpaadippikkunna affinity reyejantukalaanu, angane mrugangale ulppaadana prakriyayil ninnu poornnamaayum illaathaakkunnu. synthetic aantibodikalil recombinent aantibodikal, nuclic assid aptamerukal, noonn-immunoglobulin protein scarfoldukal enniva ulppedunnu. avayude inn vitro nirmmaana reethiyude anantharafalamaayi synthetic aantibodikalude aantijan recognission saitt aavasyamulla eathu lakshyathilekkum enchiniyaring cheyyaan kazhiyum, koodaathe prakrithidatha aantibodikal vaagdaanam cheiyunna saadhaarana rogaprathirodha shekharathinappuram vyaapikkukayum cheyyaam. gaveshanam, roganirnayam, chikitsa prayogangal ennivayil upayogikkunnathinaayi synthetic aantibodikal vikasippichukondirikku. parambaraagatha monoclonal allengil polyclonal aantibodikal upayogikkunna ellah aaplikkeshanukalilum synthetic aantibodikal upayogikkaam, koodaathe thaarathamyena kuranja ulppaadanachelavu, reactor punarnirmmanakshamatha, pareekshanathmaka saahacharyangaliludaneelam vardhicha aduppam, prathyekatha, sthiratha enniva ulppede mrugangalil ninnu uruthirinja aantibodikalekkaal niravadhi antharleenamaaya gunangal vaagdaanam cheiyunnu.
recombinent aantibodikal.
synthetic jeenukal upayogichu inn vitroyil uthpaadippikkunna monoclonal aantibodikalaanu recombinent aantibodikal. recombinent antibody saankethikavidyayil uravida koshangalil ninnu antibody jeenukal veendedukkuka, jeenukale uchithamaaya vektaraayi vardhippikkukayum kloon cheyyukayum cheyyuka, vektarine oru hosttilekku avatharippikkuka, mathiyaya alavil pravarthanaparamaaya antibody aavishkaaram kaivarikkuka enniva ulppedunnu. anuyojyamaaya oligo nucleotide primerukaloo hybridisation probukaloo labhyamaanengil, antibody uthppaadippikkunna eathu inam mrugangalil ninnum recombinant aantibodikal kloon cheyyaan kazhiyum. antibody jeenukal kaikaaryam cheyyaanulla kazhivu puthiya aantibodikalum, fab sakalangal, ezz. sii. eph. vii inn vitro polulla antibody shakalangalum srishtikkaan saadhyamaakkunnu. echu, ell shringalakalude puthiya kombineshanukal undaakkikkond muzhuvan compining saittinteyum thalatthil ithu cheyyaan kazhiyum. vyakthigatha cdrsukale parivartthanam cheythum ithu cheyyaan kazhiyum. display librarikal, saadhaaranayaayi fejilo yeesttilo prakadippikkunnu, antibody shreniyile atharam mattangalil ninnu undaakunna abhikaamyamaaya swabhaavasavisheshathakal thiranjedukkaan vishakalanam cheyyaam.
immunoglobulin ithara synthetic aantibodikalil ninnu uruthirinjathaanu.
eee thanmathrakal saadhaaranayaayi oru antibody ghadanayil vyathyaasappettirikkunnu, avaa nuclic aasidukalil ninno, aaptemarukalude kaaryatthilennapole, allengil noonn-immunoglobulin protein scarfoldukal/pepttaid aaptaamarukalil ninno utppaadippikkaam, athilekku hyperveriable looppukal cherthu aantijan binding saitt roopappeduthunnu. protein scarfoldinullil iruvashathum hyperveriable binding lupe niyanthrikkunnath synthetic antibody swaabhaavika antibodiyumaayi thaarathamyappeduthunnathi kaviyunnathino ulla alavumaayi bandhippikkunna bandhavum savisheshathayum mechappeduthunnu. saadhaarana antibody gadanayude upayogavumaayi thaarathamyappeduthumbol eee thanmaathrakalude pothuvaaya gunangalil cheria valippam, mechappetta tissue nuzhanjukayattam, swaabhaavikavum punasamyojithavumaaya aantibodikalkk maasangale apekshichu aazhchakalude drutha utppaadana samayam, vilakuranja chelavu enniva ulppedunnu.
affimer proteinukal.
12-14 kda enna tanmatra bharamullah cheria sakthamaaya affinity reyejantukalaanu affimer proteinukal. avaa uyarnna aduppavum prathyekathayum ulla avarude taargett proteinukalumaayi bandhippikkunnathin enchiniyaring cheythavayaanu, athinaal avaa synthetic antibody kudumbatthile amgamaanu.
sistaattinukalude sisttain protees inhibittar kudumbatthil ninnaan affimer protein scarfold uruthirinjathu. protein scarfoldinullil rund variable pepttaid looppukalum oru variable enn-terminal sequence undu, athu nirddishta taargett protein uyarnna affinity binding uparithalam nalkunnu. niravadhi molecular recognission aaplikkeshanukalil upayogikkunnathinaayi ubiquitin cheyinukal, immunoglobulin, sii-reactive protein ennivayulppede niravadhi lakshyangalilekk affimer binderukal nirmmichittundu.
gaveshanam, diagnostic, chikitsa prayogangal ennivaykkaayi reyejantukalaayi affimer binderukal vikasippikkunna avakta life sciences affimer saankethikavidya vaanijyavalkkarikkukayum vikasippikkukayum cheythu.
aaplikkeshanukal.
synthetic aantibodikal niravadhi prayogangalil avayude prayojanam kaanichittundu. gaveshanamekhalayil avayude upayogam pradhaanamaayum jeevashaasthrathil protein pidichedukkunnathinulla reagentukalaayum protein inhibittarukalaayum aanu. roganirnayathil anubadha, cancer screening muthal dhaanya saambilukalile micotoxin kandethal vareyulla prayogangalil avaa upayogichittundu. synthetic aantibodikalaanu nilavil chikilsayude athivegam valarunna vibhaagam.