
edward emm. robertis

edward maikkal dii robertis (jananam juun 6,1947) oru american bhroonashaasthranjanum loss enjalsile california sarvakalaashaalayile professorumaanu. mrugangalude vikasana samayat tissue vyathyaasangalkk kaaranamakunna bhroona inductionukalude samrakshitha tanmatra prakriyakal kandethunnathinu addehathinte pravartthanangal sambhavana cheythittundu. 2013ll naashanal akkadami oof sayansilekku thiranjedukkappetta addeham 26 varsham howard hugs medical instittyoottil jolie cheyyukayum loss enjalsile california sarvakalashaalayil vishishta professoraayi pravartthikkukayum cheythu. 2009ll benedict pathinaraman marpappa dii robertisine pontifical akkadami oof sciencesil aajeevanantha sthaanathekku niyamikkukayum 2022ll francis marpappa addehathe naalu varshathekku academyude kaunsilaraayi niyamikkukayum cheythu. 
aadyakaala jeevithavum vidyaabhyaasavum.
edward dii robertis 1947 juun 6 nuu masaachyusetsile cambridgil janichappol addehathinte pithaav neurobiologist edwardo diego dii robertis oru poost doctoral fello aayirunnu. moonnu vayass muthal addeham urugvaayilaanu valarnnathu, avide 24-aamm vayassil yooniversitti dii laa republica dell urugvaayil ninnu medical birudam nedi. ithine thudarnnu oru piechu poortthiyaayi.dii. arjanteenayile buenos airsile leloyar instittyoottil ninnu rasathanthrathil birudam nedi. 
currier gaveshanavum.
dii robertisinte poost doctoral pariseelanam (1974-1977) englandile kembridjile medical research kaunsilil nobal sammana jethaav sarr joonn gurdanodoppamaayirunnu.
1984-ll, dii robertis thante antharicha sahapravarthakanaaya walter gehrings avarude laborattarikalum chernnu aadyathe kasherukkalude vikasanam niyanthrikkunna jeenine kloon cheythu, innu ithu hooks-sii 6 ennariyappedunnu. hooks jeenukal munbhagathu ninnu posteeriyar (thala muthal wall vare) vyathyaasathin kaaranamaakunnu. kasherukkalilum pazha eechakalilum hooks jeenukal samrakshikkappedunnu enna kandethal parinaamathinteyum vikasanathinteyum puthiya shaasthreeya mekhalayaaya ivo-devoyude thudakkamaayi prakhyaapichu.
1990kalil dii robertisinte laborattari bhroonapraveshanathinu madhyasthatha vahikkunna tanmatra paathakale chittayayi vichedichu. 1924ll hans speman hilde mangold ubhayajeevikalude bhroonathinte oru pradesham kandethi, athu parichunadumbol, sayamese erattakalude srishtiye prolsaahippikkaam. gooscoid" homeobox jeenil ninnu aarambhich eee pradeshathe "senopus" bhroonangalil prakadippikkunna jeenukale dii robertis thiricharinju. 
thante sahapravarthakarumaayi chernnu, asthi morphogenetic protein (bii. emm. pii) valarchaa gadakangale bandhippikkunna dorsal koshangal sravikkunna proteinaaya cordin addeham kandethi, ithu bhroonathinte ventral bhaagathekku avaye kondupokunnathinu sahayikkunnu, avide tolloid enna protees vazhi cordin dahikkukayum bii. emm. pii. kalkk veendum signal nalkaan anuvadikkukayum cheiyunnu. pazha eechakal, chilanthikal, aadyakaala cordettukal, sasthanikal thudangiya mikka ubhaykakshi enangalilum, valarchaa gadakangalude eee ozhukk dorsal (puram) muthal ventral (wier) koshatthilekkum tissue deferentiationilekkum nirnnayikkunnu. cordin/bii. emm. pii/tolloid biochemical paatha dablyu. enn. tii polulla mattu signalling paathakalumaayulla edapedalukaliloode cross-regulate cheiyunnu. addehathinte laab aduthide canonical doubluenty pathway, macropinocytosis, multivisicular endosomes, lysosomukal, protein degradation enniva thammilulla oru bandham sthaapichu.
pyoo chaarittabil trasttukalude laattin american phelos prograaminte scientific boardilum addeham rund pathittaandilere sevanamanushtichittundu.

