parinamaparamaaya bagej

munkaala vyakthikalil prayojanakaramaayirunnenkum innu prakrithinirnnayathinte sammarddathil doshakaramaaya oru janasamkhyayude genome bhagamaanu parinamaparamaaya bagej.
uthbhavam.
munkaalangalil prayojanakaramaayirunna jeenukal innathe paristhithiyile vyakthikalkk gurutharamaaya reethiyil anuyojyamallayirikkaam. prakrithinirnnayam oru thikanja prakriyayalla; oru prathyeka paristhithiye athijeevikkunnathinum punarnirmmikkunnathinum oru jeevi "paryaapthamaanenkil", athinte jeenukal adutha thalamurayilekku kaimarunnu. eee jeenukalil chilath oru jeeviyude shaareerikakshamatha vardhippikkumbol chilath alppam doshakaravumaakaam. eee vairudhyam parinamaparamaaya baagejinte uthbhavamaan, ithu varthamaanakaalathil ninnu vyathyasthamaaya anthareekshathil parinamicha koottaaya paarambarya swabhaavasavisheshathakalaanu.
sickle sellum maleria.
oru resussive jeane enna nilayil, sickle sell rogam homocygus aanenkil maathrame undaakoo, avaye marikadakkaan prabalamaaya jeane illa. malaria vyapakamaaya ushnamekhalaa pradeshangalil thamasikkunna aalukalil ninnu uthbhavikkunna sickle sell rogam, karkkasavum ariwal aakruthiyilullathumaaya chuvanna rakthaanukkalude savisheshathayulla oru paarambarya raktha vaikalyamaan.. eee marria chuvanna rakthaanukkalude asaadhaaranamaaya aakruthiyum kaadinyavum pathivayi rakthayottathode phalapradamaayi sanjarikkaanulla oru koshatthinte kazhivine kuraykkunnu, idaykkide sirakale thadayukayum sariyaaya rakthayottam thadayukayum cheiyunnu. sickle sell rogamullavarude aayurdairkhyam kuravaanu, ennirunnaalum aadhunika vaidyashaasthram eee rogamulla oraalude aayurdairkhyam ganyamaayi vardhippichittundu. sickle sell rogathinte prathyaaghaathangal haanikaramaanennu thonnunnathupole, ithu apratheekshithamaya oru nettavum nalkunnu; sickle sell jeane ulla manushyar malaria baadhikkumbol gurutharamaaya lakshanagal kanikkunnilla, kaaranam rogam moolamundaakunna rakthaanukkalude asaadhaarana aakruthi malaria paraannabhojiyude eee kosangalkkullil akramikkunnathinum aavarthikkunnathinum ulla kazhivine thadassappeduthunnu. sickle sell alleel undakaan saadhyathayund, pakshe rogam illa, udaaharanathinu heterosaigas aanenkil.
manushyarilum mattu mrugangalilum kothukukal parathunna pakarchavyaadhiyaaya malaria, panii, ksheenam, ookkaanam, peshi vedana, chuma, angeyattatthe kesukalil cooma, maranam ennivaykku kaaranamakunna marakamaaya rogamaanu. kothukukalude umineer vazhi oru vyakthiyude rakthachamkramana samvidaanathilekku kaimaattam cheyyappedunna parannabhojikalaaya protosovanukal moolamaanu malaria undaakunnath, avide avaa karalilekku sanjarichu pakwata praapikkunnu. yuu. yill ozhivaakkappettenkilum.ezz.lokaarogya samghadanayude kanakkanusarichu 2010ll 21.9 dasalaksham malaria kesukal rekhappeduthiyittundu.
ariwal kosha rogavum maleria thammilulla parasparabandham oru erattathavana vaal aanu. sickle sell alleel ullathinaal oru vyakthiyude aayurdairkhyam parimithappedunnu, ennirunnaalum sickle sell jeenukalude saannidhyam maleriyayude doshakaramaaya prathyaaghaathangal kuraykkunnu. malaria vahikkunna kothukukalude ennam kooduthalulla pradeshangalil ariwal-kosha jeane padaraan prakrithinirnnayam anuvadichu; malariaykku athratholam irayaakaathavar jeevikkaan saadhyatha kooduthalaayirunnu. malaria pandattheppole prachaaratthilillaathinaal, ariwal koshatthinte gunangal pinneedu kshayichupoyi, rogathinte doshakaramaaya prathyaaghaathangal avasheshikkunnu.

