
barbara samrajya

barbara samrajya (bee. 1 janwari, 1957) massachusets praudyogiki sansthaan mein jeev vigyaan aur rasayan vigyaan key professor hain aur vyaapak sansthaan key sambaddh sadasya hain. vaha rashtriya vigyaan akadami kii nirvaachit sadasya aur rasayan vigyaan key shaahi samaaj kii ack sadasya hain.
shiksha aur praarambhik jeevan.
imperial kaa paalan-poshan ingland mein huaa thaa aur unhone surre mein caterham mein southbank school mein padhaai kii, usake baad croydon mein koloma vyaakaran school mein padhaai kii, jahan unhone vigyaan kaa adhyayan karane mein visheshagyata praapt kii. unhone 1979 mein university college landan seey aushadhiya rasayan vigyaan mein snaatak praapt kiya. unhone massachusets institute off technology mein bhaag liya, jahan unhone 1983 mein synthetic carbonic rasayan vigyaan mein darshan key doctor praapt kiye. vaha satoro masamune kii prayogshala mein shamil hoe gaeen, joe antibiotic rasayanon key ack varg koo sanshleshit karane key liye naee takneekon koo vikasit karane aur lagu karane key liye kaam curr rahee theen jinhen ensamicin key roop mein jaanaa jaataa haye. masamoon prayogshala mein ack postdock key roop mein unhone beeta-catotheolase enzyme key saath kaam kiya.
unhone robert abels kii prayogshala mein brandes vishvavidyalaya mein atirikt postdoctoral shodh kiya, jahan unhone rasayanik jeev vigyaan designing, sanshleshan aur peptide-adharit protease avrodhakon kaa mulyankan karane kaa prashikshan praapt kiya.
shodh.
1986 mein, imperial 1989 mein california praudyogiki sansthaan mein apani prayogshala koo sthanantarit karane seey pahale kaarnegi melan vishvavidyalaya mein ack sahayak professor bunn gaee. caltech mein, vaha dennis doggerty key shodh seey prabhaavit thee, joe ligand-gated jhilli chainalon aur receptors kii baatchit koo samajhane key liye apraakritik amino acid utparivartan koo lagu curr rahee thee. imperially kaa kaam rasayan vigyaan-jeev vigyaan interfaces mein samasyaon parr kendrit hoe gayaa, rasayan vigyaan kaa upayog karke protein kii sanrachana aur kaary koo behtar dhang seey samajhane key liye.
1999 mein, vaha jeev vigyaan key ellen swello richard professor key roop mein vaapas aaee. unakaa shodh karyakram protein glycosylation parr kendrit haye, ack aisee prakriya jisake dwara ack carbohydrate koo protein mein isaki sanrachana yaa kaary koo badalane key liye jodaa jaataa haye. unaki prayogshala ney yeh samajhane key liye takneek vikasit kii haye kii protein utpaadan key samay glycosylation-ack prakriya jise anuvaad key roop mein jaanaa jaataa haye-protein folding aur sanrachana koo kaise prabhaavit kartaa haye. pratideepti anunaad oorjaa hastaantaran aur paramanu chumbakiya anunaad jaisi takneekon koo lagu karate hue, unhone spasht kiya haye kii glycosylation protein koo galat tareeke seey modane seey kaise bachaa sakata haye aur yeh taha yantriki aur ushmaagatiki sthirata koo kaise prabhaavit kartaa haye.
glycosylation kaa adhyayan karane key alawa, imperially ney vibhinn prakaar key anuprayogon key liye jaiv rasayanik prakriyaon koo samajhane aur herfer karane key liye rasayanik drishtikonon koo kaise design, vikasit aur lagu kiya jaae, isaki jaanch kaa bhee netritva kiya haye. unake samooh ney kinnes kii gatividhi kii nigrani key liye peptides aur protein key phosphorylation kaa pataa lagaane key liye ack pratideepti-adharit vidhi vikasit karane key liye sahyog kiya haye, joe enzyme hain joe phosphorylation koo utprerit karate hain aur cellular gatividhiyon kii ack vishal shrinkhala kaa samanvaya karate hain. iss vidhi koo protein kinnez avrodhakon key liye screen parr lagu kiya jaa sakata haye aur koshikaon aur ootakon mein unaki gatividhiyon kii nigrani kii jaa sakati haye, jisase sanket maargon parr nazar rakhee jaa sakati haye aur cancer jaisi beemariyon key liye ack sambhaavit naidaanik upkaran pradaan kiya jaa sakata haye joe baadhit kinnez-madhyasth viniyaman key parinamswarup hoe sakata haye.
unhone "chemical glycobiology" naamak paathyapustak bhee likhi haye.

