
cloperastine

cloperastine (inn) yaa cloperastine, cloperastine hydrochloride (zaan) (brand naam hustazole, nitosyl, seki) aur cloperastine fendizoate (yaa hibenzoate) key roop mein, ack antitusive aur antihistamine haye jise japan, hangkang aur kuchh europeeya deshon mein ack khansi damnak key roop mein vipanan kiya jaataa haye. ise pahali baar 1972 mein japan mein aur phir 1981 mein itali mein pesh kiya gayaa thaa.
dushprabhaav.
pratikool prabhaavon mein shaamak, unindapan, seene mein jalan aur shwas nully key sraav kaa motaa honah shamil hoe sakata haye.
pharmacology.
cloperastine kii kriya kaa sateek tantra poori tarah seey spasht naheen haye, lekin dawa key liye kaee alag-alag javic gatividhiyon kii pehchaan kii gaee haye, jinamen shamil hainh σ1 receptor kaa ligand (kii = 20 nm) (sambhavatah ack agonist), girk channel blocker ("shaktishali" key roop mein varnit), antihistamine (kii = 3.8 nm aich1 receptor key liye), aur anticholinergic. aisaa maanaa jaataa haye kii baad key dou guna dushprabhavon mein yogdan karate hain, jaise kii shaamak aur somanolens, jabaki poorv dou cloperastine kii antitusive prabhavkarita mein shamil yaa jimmedaar hoe sakate hain.
sanshleshan.
tetrachloromethane mein phosphorus tribromide key saath 4-chlorobenzhydrol [119-56-2] (1) key halogen seey 1-(bromophenylmethyl)-4-chlorobenzine [948-54-9] (2) milata haye. ethylenechlorohydrine (2-chloroathenol) [107-07-3] (3) key saath upchaar 1-(4-chlorobenzhydryl) auxi-2-chloroethane [5321-46-0] (4) detaa haye. piperidine (5) key saath pratikriya "cloperastine" (6) key sanshleshan koo puuraa karati haye.