
heteropodatoxin

heteropodatoxin vishal kekade kii makadi "heteropoda venetaria" key jahar seey nikalane vaale peptide vish hain, joe kv4.2 voltage-gated potasium chainalon koo avaruddh karate hain.
srot.
heteropodatoxin koo vishal kekade kii makadi, "heteropoda venetaria" key jahar seey shuddh kiya jaataa haye.
rasayan vigyaan.
heteropodatoxin mein ack avarodhak cystine gaanth (aaee. see.) rupankan hotaa haye, jisamen ack compact diasulphide-bandhe core hotey hain, jisase chaar loop nikalate hain. teen alag-alag heteropodatoxin hainh
yeye teen vishaakt padaarth sanrachanaatmak roop seey 29-32 amino acid key samaan peptide hain. way hanatoxin key saath anukram samaantaa dikhaate hain, jinhen chilly key gulab tarantula gramostola gulab key jahar seey alag kiya jaa sakata haye.
lakshya.
heteropodatoxin aeye-prakaar, kshanik voltage-gated potasium chainalon koo avaruddh karate hain. teenon vishaakt padarthon koo potasium channel kv4.2 koo avaruddh karane key liye dikhaaya gayaa haye. punarsanyojit heteropodatoxin-2 potasium channel kv4.1, kv4.2 aur kv4.3 koo avaruddh kartaa haye, lekin kv1.4, kv2.1, yaa kv3.4 koo naheen.
kaarravaai kaa tarika.
heterpodatoxin-2 sambhavatah kv4.2 chainalon key getting parivartak key roop mein kaary kartaa haye. yeh sakriyan kii voltage nirbharta aur kv4.3 potasium channel key nishkriyata koo adhik sakaratmak moolyon mein sthanantarit kartaa haye. natijatan, vishaakt padaarth kii upasthiti mein iss channel key nishkriya honey kii sambhavana adhik hoti haye aur channel koo kholane key liye ack badey vidhruveekaran kii aavashyakta hoti haye. haalaanki, heterpodatoxin-2 ney kv4.1 channel kii voltage nirbharta koo prabhaavit naheen kiya, yeh sujhaav dete hue kii block key sateek tantra koo spasht kiya jaanaa baaki haye, aur ack chhidra avarodhak key roop mein ack bhoomika koo baahar naheen kiya jaa sakata haye. kv4.2 block kii voltage nirbharta teen alag-alag heteropodatoxin key beach bhinn hoti haye. yeh aich. pee. tii. aiks. 2 yaa aich. pee. tii. aiks. 3 kii tulanaa mein aich. pee. tii. aiks. 1 key liye cumm voltage nirbhar haye.
vishaaktata.
vishal kekada makadi sthaaniya roop seey dardanaak kaatane kaa kaaran bunn sakati haye.

