
ischemic stroke kaa computational modeling

ischemic stroke key computational modeling kaa upayog ischemic stroke key dauran javic ghatnaaon koo samajhane aur sambhaavit dawa lakshyon kii pehchaan karane key liye kiya gayaa haye. yeye model aam taur parr sadharan vibhedak samikaranon aur aanshik vibhedak samikaranon key saath compartment model kaa upayog karate hain. avasaad aur aayan gatiki key prasaar key models seey pataa chalaa haye kii calcium, sodium aur chlorine key pravaah key kaaran neuronal gatividhi cumm hoe jaati haye aur soojan badh jaati haye, aur gambhir aur madhyam ischemic stroke ghatana key dauran neurons mein potasium aur glutamate kaa pravaah hotaa haye. ack aghaat key dauran ph key computational modeling seey yeh bhee pataa chalaa kii chayapachaya gatividhi mein kamee aur neurons mein lactate aur carbon dioxide sandrata mein vriddhi key kaaran, penumbra kaa ph cumm hoe jaataa haye. yeye parinam "inn vitro" aur "inn vivo" adhyayanon seey sahmat hain. inn computational model kaa upayog ack ischemic stroke ghatana key liye vishisht kaee jatil tantron koo ekikrit karke protein yaa receptors kii pehchaan karane mein madad karane key liye kiya jaa sakata haye.
aeye. dee. aim. ee. kaa upayog karke lakshit dawa kaa upayog vishisht receptors yaa protein koo lakshit karane key liye davaaon kii pehchaan karane mein kiya gayaa haye, jinhen ack ischemic stroke ghatana mein pahachaana gayaa haye. udaaharan key liye, aghaat aine. aff.-key. bee. kii atee abhivyakti koo prerit curr sakata haye. yeh atee abhivyakti soojan aur neuronal apoptosis kaa kaaran banati haye. adme kaa upayog karke, shodhkarta ack dawa lakshya koo sanshleshit karane aur pahchaanane mein saksham they, jiska aine. aff.-key. bee. key saath uchch bandhan sambandh thaa taaki isake sthanantaran koo rokaa jaa sakey. iss takneek kaa upayog mastishk kii chot sthal mein chikitsiya lakshyon koo sthanantarit karane mein madad karane key liye rakt-mastishk baadha mein paae jaane vaale collin receptor key saath uchch sambandh vaale anuon kii pehchaan karane key liye bhee kiya gayaa thaa.

