
taakat kaa patthar

trangestone, jise retroid, retroid aur retron brand naamon key tahat becha jaataa haye, ack progestine dawa haye jiska upayog pahale masik dharm vikaaron key ilaaj key liye kiya jaataa thaa, lekin abb iska vipanan naheen kiya jaataa haye. ise munh seey liya jaataa haye.
strangestone key dushprabhavon mein sirdard, thakan aur stun mein komalata shamil hain. trangstone ack progestine, yaa ack synthetic progestogen haye, aur isaliye progesterone receptor kaa ack agonist haye, joe progesterone jaise progestogen kaa javic lakshya haye. yeh androgenic yaa astrogenic naheen haye.
1974 mein chikitsa upayog key liye strangestone pesh kiya gayaa thaa. yeh abb upalabdh naheen haye.
chikitsa upayog.
masik dharm vikaaron key upchaar mein strangestone kaa upayog kiya jaataa thaa. iska upayog ausatan lagbhag 50 pratishat safalata darr key saath andashay koo prerit karane key liye bhee kiya gayaa haye.
dushprabhaav.
strangestone key dushprabhavon mein sirdard, thakan aur stun mein komalata shamil hain. yeh androgenic naheen haye aur mardana honey kaa kaaran naheen banata haye.
pharmacology.
pharmacodynamics.
trainstone ack progestogen, yaa progesterone receptor kaa agonist haye. yeh diadrogesterone key samaan ack asamanya progestogen haye. udaaharan key liye, anya progestogen key vipareet, trangstone aur diadrogesterone shareer key tapman mein vriddhi naheen karate hain (i.ee., koee atiushna prabhaav naheen haye). isake alawa, jabaki anya progestogen antigonadotropic hotey hain aur ovulation koo rokte hain, diadrogesterone naa tou antigonadotropic hotaa haye aur naa hii progonadotropic hotaa haye aur ovulation koo prabhaavit naheen kartaa haye, aur trangestone progonadotropic prateet hotaa haye aur iska upayog ovulation koo prerit karane key liye kiya jaa sakata haye. diadrogesterone aur progesterone key samaan, trangstone mein koee androgenic yaa astrogenic gatividhi naheen hoti haye.
pharmacokinetics.
strangstone 20α-dihydrotrenstone (20α-dhtg) kii ack upaj prateet hoti haye, kyonki yeh maukhik prashaasan parr kaafee hudd taka iss pramukh chayapachaya mein badal jaati haye. 20α-dhtg mein shaktishali progestogenic gatividhi hoti haye, jisamen iss chayapachaya kaa charam star trangstone key prashaasan key baad 2 seey 4 ghante mein hotaa haye aur 8 seey 14 ghante key javic ardh-jeevan key saath hotaa haye. mootra mein 41 seey 46 pratishat aur mull mein 30 pratishat taka aparivartit roop seey trangestone utsarjit hotaa haye, joe yeh sujhaav detaa haye kii dawa kaa ack mahatvapurna hissa gastroentestinal tract seey avashoshit naheen hotaa haye. trangestone key chayapachaya aur pharmacokinetics kii sameeksha kii gaee haye.
rasayan vigyaan.
strangstone, jise 1,6-diedhydro-6-chlororetroprogestrogest yaa 6-chloro-9β, 10α-pregna-1,4,6-triane-3,20-dione key roop mein bhee jaanaa jaataa haye, ack synthetic pregnany steroid haye aur progesterone aur retroprogesterone kaa vyutpann haye. trangestone jaise retroprogesterone vyutpann progesterone key anuroop hain jisamen 9vein carbon parr hydrogen paramanu koo α-sthiti (tala key neeche) seey β-sthiti (tala key oopar) mein badal diyaa gayaa haye aur 10vein carbon parr methyl samooh koo β-sthiti seey α-sthiti mein badal diyaa gayaa haye. isake parinamswarup ack "mudaa huaa" vinyas hotaa haye jisamen valay a aur b kaa tala c aur d key valay key neeche 60° konn parr unmukh hotaa haye. strangestone key anuroopon mein diadrogesterone (6-dehydroretroprogerogetes) aur aaro 6-3129 (16α-ethylthio-6-dehydroretroprogerogetes) shamil hain.
itihas.
1964 mein strangestone kaa sanshleshan kiya gayaa thaa aur 1974 mein roach dwara chikitsa upayog key liye pesh kiya gayaa thaa.
samaaj aur sanskriti.
samanya naam.
"trangstone" dawa kaa samanya naam haye aur iska. ise isake poorv vikasatmak code naam "row 4-8347" seey bhee jaanaa jaataa haye.
brand naam.
trangestone kaa vipanan brand naam retroid, retroid aur retron key tahat kiya gayaa thaa.
upalabdhata.
strangstone kaa abb vipanan naheen kiya jaataa haye aur isaliye abb kissy bhee desh mein upalabdh naheen haye.