
neena papavasilio

neena papavasilio germany key headleberg mein german cancer anusandhaan kendra mein pratiraksha vividhata key vibhajan mein ack pratiraksha vigyaani aur helmholtz professor hain. vaha rockfeller vishvavidyalaya mein ack sahayak professor bhee hain, jahan way pahale sahayogi professor aur lymphocyte jeev vigyaan kii prayogshala kii pramukh theen. vaha dee. aine. aeye. aur aar. aine. aeye. sampadan key kshetra mein apane kaam key liye jaani jaati hain.
shiksha aur praarambhik jeevan.
papvasilio ney 1992 mein jeev vigyaan mein oberlin college seey vigyaan mein snaatak kii upaadhi praapt kii. phir unhone michel see mein rockfeller vishvavidyalaya seey phd poori kii. nussenzweig kii aanvik pratirakshan vigyaan kii prayogshala. vahaan, unhone adhyayan karna shuru kiya kii kaise bee koshika pratijan receptors-yaa koshika jhilli seey lunger daale gaye antibody-utparivartan seey gujarate hain taaki way vishesh roop seey ack vishesh pratijan koo pehchaan sakein aur ack pratiraksha pratikriya praapt curr sakein. unhone yell school off medicine mein usa ruchi kaa paalan kiya, jahan unhone david jee kii prayogshala mein postdoctoral fellow key roop mein kaam kiya. skatz.
shodh karein.
papvasilio kaa shodh yeh spasht karane parr kendrit haye kii kaise koshikaaen aur jeev dee. aine. aeye. aur aar. aine. aeye. donon staron parr apane genome mein encode kii gaee jaankaari mein vividhata laate hain aur uska vistaar karate hain. unhone 2001 mein sahayak professor key roop mein rockfeller vishvavidyalaya mein lymphocyte jeev vigyaan kii apani prayogshala kholi. unake samooh kaa adhikansh praarambhik kaam anukuli pratiraksha pratikriya key sandarbh mein kiya gayaa thaa, joe teji seey nae antibody utpann karke mezban parr aakraman karane kii maang karane vaale rogjanakon kii ack vistrit shrinkhala kaa mukabala karane mein saksham haye joe vishesh roop seey diye gaye aakramankari koo pahchaanane mein saksham hain. unake samooh ney sakriyan-prerit cytidine deminase (sahaayata) key roop mein jaane jaane vaale enzyme kii gatividhi koo chihnit karane key liye kaam kiya haye. sahaayata dee. aine. aeye. mein cytidine (see) avasheshon koo uracil (yuu) mein badal detee haye, jise dee. aine. aeye. kshati key roop mein pahachaana jaataa haye aur iss tarah seey marammat kii jaati haye joe thymidine (tii) kaa parichay detee haye, prabhaavi roop seey dee. aine. aeye. mein see. aiss. koo tii. aiss. mein parivartit karati haye. iss prakriya koo shaaririk atee utparivartan key roop mein jaanaa jaataa haye aur yeh haye kii kaise bee koshikaaen teji seey receptors mein dee. aine. aeye. utparivartan kaa parichay dey sakati hain joe aakramankariyon koo pahachaante hain, jinhen antigen key roop mein jaanaa jaataa haye. papavasilio kii prayogshala ney yeh samajhane key liye kaam kiya haye kii pratiraksha pranali mein sahaayata abhivyakti koo kaise niyantrit kiya jaataa haye aur sahaayata utparivartan key liye kuchh jeane koo kaise lakshit karati haye.
papvasilio aar. aine. aeye. sampadan lakshyon kii pehchaan karane aur unaki visheshtaon koo spasht karane key liye agali peedhi key anukraman aur jaiv soochana vigyaan drishtikon kaa upayog karke janmajaat pratiraksha pratikriya key sandarbh mein aar. aine. aeye. sampadan kaa bhee adhyayan kartaa haye. unake samooh ney pahali baar apoback 1 key nae aar. aine. aeye. sampadan lakshyon kii pehchaan kii, joe ack aar. aine. aeye. pratilekh mein ack cytosine koo uracil mein parivartit kartaa haye, aur pahale socha jaataa thaa kii yeh kewal chhoti aant mein apolypoprotein bee (apob) koo sampaadit kartaa haye. usake baad seey uska samooh sambhaavit bhoomika koo chihnit karane kaa prayaas karane key liye aage badhaa haye joe kii apoback 1-sampadan apob key saath apane kaary key baahar khel rhaa hoe sakata haye.
papavasilio ney haal hii mein ack model jeev key roop mein, african neend kii bimari kaa kaaran banane vaale parjivi, trypanosoma brucei kaa upayog karate hue, pratijan bhinnata key tantra kaa adhyayan karane key liye shaakhaaen banaai hain-yaa rogjanak pratiraksha pratikriya seey bachane key liye apane satah protein koo kaise badalate hain. unake samooh ney trypanosome mein protein coat switching kii gatishilata koo behtar dhang seey samajhane key liye nae upkaran vikasit kiye hain, aur una tantron koo behtar dhang seey samajhane key liye kaam curr rhaa haye jinake dwara trypanosome sankraman key dauran apane coat protein mein vividhata laane mein saksham hain.
2016 mein, papvasilio europeeya anusandhaan parishad key samekak anudan seey atirikt samarthan key saath pratiraksha vividhata key vibhajan mein apani prayogshala shuru karane key liye german cancer anusandhaan kendra mein chully gaeen.

