
phytosterol

phytosterol collestroll key samaan phytosteroid hain, joe paudhon kii javic jhilli key sanrachanaatmak ghatakon key roop mein kaam karate hain. way paudhon key sterol aur stanol koo shamil karate hain. 250 seey adhik sterol aur sambandhit yaugikon kii pehchaan kii gaee haye. telon seey nikaale gaye mukt phytosterol paani mein aghulansheel hotey hain, tail mein apekshaakrit aghulansheel hotey hain aur alcohol mein ghulansheel hotey hain.
phytosterol-samriddh khaadya padaarth aur aahar poorak dashakon seey vipanan kiye jaa rahey hain. phytosterol key deerghakaalik sevan seey achchi tarah seey pralekhit ell. dee. ell. collestroll-cumm karane vaale prabhaavon key bavjood, hriday rogon, upvaas rakt sharkara, glyceted haemoglobin, yaa samagr mrityu darr parr prabhaav key liye aparyaapt pramaan hain.
sanrachana.
unake paas ack fused polycyclic sanrachana hoti haye aur carbon side chain aur/yaa dohare bandhan (santripti) kii upasthiti yaa anupasthiti mein bhinn hoti haye. carbon-4 sthiti mein methyl samoohon key sthaan key aadhar parr unhein 4,4-diamethyl phytosterol, 4-monomethyl phytosterol aur 4-desmithyl phytosterol mein vibhajit kiya gayaa haye. stanol santript sterol hotey hain, jinamen sterol ring sanrachana mein koee dohare bandhan naheen hotey hain.
lekh key seese mein anu β-citosterol haye. namkaran daaeen or dikhaaya gayaa haye.
isake alaavaah
aahar mein phytosterol.
phytosterol key sabse samriddh praakritik srot vanaspati tail aur unase baney utpaad hain. sterol mukt roop mein aur fatty acid ester aur glycolipid key roop mein maujood hoe sakate hain. baddh roop aamtaur parr agnyashay enzymon dwara chhoti aanton mein hydrolysed hotaa haye. halanki, kuchh sterol koo refining telon aur vasaa key durgandh unmoolan charan key dauran unaki saapeksh sanrachana koo badale binaa hataa diyaa jaataa haye. isaliye sterol pramanikta kii jaanch karane mein ack upayogi upkaran hain.
phytosterol key samanya sroton key roop mein, vanaspati telon koo phytosterol samagri koo ujagar karane vaale margerine utpaadon key roop mein vikasit kiya gayaa haye. anaaj utpaad, sabjiyaan, phal aur jamun, joe phytosterol mein utane samriddh naheen hain, unake uchch sevan key kaaran phytosterol key mahatvapurna srot bhee hoe sakate hain.
praakritik roop seey paae jaane vaale phytosterol kaa sevan khaane kii aadton key aadhar parr ~ 200-300 milligram/dinn key beach hotaa haye. vishesh roop seey taiyar kiye gaye shakahari prayogaatmak aaharon kaa utpaadan 700 milligram/dinn seey adhik utpaadan key saath kiya gayaa haye. maanav aahar mein sabse adhik paae jaane vaale phytosterol beeta-citosterol, campesterol aur stigmasterol hain, joe kramshah lagbhag 65 pratishat, 30 pratishat aur 3 pratishat aahar samagri key liye jimmedaar hain. maanav aahar mein sabse aam paudha "stanol" citostanol aur campestenol hain, joe sanyukt roop seey aahar phytosterol kaa lagbhag 5 pratishat banaate hain.
swaasthya daave.
aff. aiss. aeye..
europeeya khaadya suraksha pradhikaran (ee. aff. aiss. aeye.) ney nishkarsh nikala kii yadi koee vyakti prati dinn 1.5 seey 2.4 graam paudhe key sterol aur stanol kaa sevan kartaa haye, tou rakt collestroll koo ausatan 7 seey 10.5% taka cumm kiya jaa sakata haye, joe aamtaur parr 2-3 saptah key bheetar sthaapit hotaa haye. 85 saptah taka key deerghakaalik adhyayanon seey pataa chalaa haye kii collestroll koo cumm karane kaa prabhaav banaa reh sakata haye. iss aur anya prabhavkarita detta key aadhar parr, ee. aff. aiss. aeye. vaigyaanik panel ney nimnalikhit swaasthya paramarsh pradaan kiyaah "paadap sterol koo rakt collestroll koo cumm karane/cumm karane key liye dikhaaya gayaa haye. rakt collestroll koo cumm karane seey coronary hriday roga kaa khatra cumm hoe sakata haye.
fda.
aff. dee. aeye. ney phytosterol key liye nimnalikhit daave koo manjuri dee haih "plant sterol ester key liye": (i) plant sterol ester kii prati seva mein cumm seey cumm 0.65 graam vaale khaadya padaarth, cumm seey cumm 1.3 graam key dainik kull sevan key liye bhojan key saath dinn mein dou baar khaae jaate hain, joe santript vasaa aur collestroll mein cumm aahar key hisse key roop mein, hriday roga key jokhim koo cumm curr sakate hain. [bhojan key naam] kii seva vanaspati tail sterol ester key _ _ _ graam kii aapoorti karati haye. "paadap stenol ester key liye": (i) paadap stenol ester kii prati seva mein cumm seey cumm 1.7 graam vaale khaadya padaarth, cumm seey cumm 3.4 graam key kull dainik sevan key liye bhojan key saath dinn mein dou baar khaae jaate hain, joe santript vasaa aur collestroll mein cumm aahar key hisse key roop mein, hriday roga key jokhim koo cumm curr sakate hain. [bhojan key naam] kii seva seey _ _ _ graam paudhe key stenol ester kii aapoorti hoti haye.
phytosterol poorak seey judey naidaanik parikshanon kii sameeksha karate hue, fda ney nishkarsh nikala kii jaba samriddh khaadya padarthon mein 1 seey 3 graam kii seema mein sevan kiya jaataa haye, tou phytosterol key parinamswarup placebo key saapeksh rakt ldl collestroll key star mein saankhyikiya roop seey mahatvapurna (5-15%) kamee aatee haye. aff. dee. aeye. ney yeh bhee nishkarsh nikala kii phytosterol key sevan aur collestroll koo cumm karane key liye phytosterol key sevan key beach sambandh koo pradarshit karane key liye phytosterol key 2 graam prati dinn (gair-asterified phytosterol key roop mein vyakt) kaa dainik aahar sevan aavashyak haye.
kanada kaa swaasthya.
swaasthya kanada ney 1994 aur 2007 key beach prakaashit 84 yaadrichhik niyantrit parikshanon key sakshya kii sameeksha kii jisamen phytosterol poorak shamil thaa. ell. dee. ell.-collestroll mein ausatan 8.8% kii kamee prati dinn 2 graam key ausat sevan parr dekhi gaee. swaasthya kanada ney nishkarsh nikala kii phytosterol kii khapat aur rakt collestroll koo cumm karane key beach sambandh kaa samarthan karane key liye paryaapt vaigyaanik sakshya maujood hain. iss sakshya key aadhar parr, swaasthya kanada ney hypercholesterolemic vyaktiyon key liye yogya khaadya padarthon key liye nimnalikhit bayanon koo manjuri deeh
praathamik vaktavyah
"[utpaad kaa namkaran] key [metrick aur samanya gharelu upaayon mein poshan tathya talika seey aakar kii seva] vayaskon mein collestroll koo cumm karane/cumm karane mein madad karane key liye dikhaae gaye paudhe key sterol kii dainik matra kaa x% pradaan kartaa haye."
dou atirikt kathan jinka upayog kissy bhee beach mein mudrit, likhit yaa graphic samagri key binaa, praathamik kathan key buggle mein sanyojan mein yaa akele kiya jaa sakata haih
"paadap sterol collestroll koo cumm karane mein madad karate hain."iss kathan kaa upayog karane parr, praathamik kathan key aakar aur pramukhta key dogune taka key aksharon mein dikhaaya jaayega.
"uchch collestroll hriday roga key liye ack jokhim kaarak haye."iss kathan kaa upayog karane parr, praathamik kathan key samaan aakar aur pramukhta vaale aksharon mein dikhaaya jaayega.
collestroll koo cumm karna.
collestroll key star koo cumm karane key liye phytosterol kii kshamata kaa pahali baar 1953 mein manushyon mein pradarshan kiya gayaa thaa. 1954 seey 1982 taka, phytosterol koo baad mein uchch collestroll key upchaar key roop mein cytellin naam seey ack dawa key roop mein vipanan kiya gayaa thaa.
statin key vipareet, jahaan collestroll koo cumm karna hriday rogon (see. vee. dee.) key jokhim koo cumm karane aur achchi tarah seey paribhaashit paristhitiyon mein samagr mrityu darr koo cumm karane key liye saabit kiya gayaa haye, sakshya phytosterol-samriddh khaadya padarthon yaa poorak key liye see. vee. dee. key jokhim koo cumm karane key liye asangat rahey hain, dou sameekshaon seey koee yaa seemant prabhaav kaa sanket naheen milata haye, aur ack anya sameeksha collestroll-cumm karane vaale prabhaav koo praapt karane key liye aahar phytosterol key upayog key liye saboot dikhaati haye.
phytosterol-samriddh khaadya padarthon key saath statin kaa saha-prashaasan, naidaanik laabh key kissy bhee pramaan key binaa aur sambhaavit pratikool prabhaavon key upakhyan sakshya key saath, phir seey phytosterol key collestroll-cumm karane vaale prabhaav koo badhaata haye. statin darr-seemit karane vaale aich. aim. jee.-coa reductage enzyme key avrodh key madhyam seey collestroll sanshleshan koo cumm karke kaam karate hain. phytosterol ack yaa kaee sambhaavit tantron key madhyam seey aant mein collestroll avashoshan key saath pratispardha karke collestroll key star koo cumm karate hain, ack prabhaav joe statin koo poorak banaata haye. phytosterol statine upayogkartaon mein collestroll key star koo lagbhag 9 pratishat seey 17 pratishat taka cumm curr detaa haye. statin kaa prakaar yaa khuraak phytosterol kii collestroll-cumm karane vaali prabhavkarita koo prabhaavit naheen karati haye.
apane collestroll koo cumm karane key gunon key kaaran, kuchh nirmaata khaadya yojak key roop mein sterol yaa stenol kaa upayog curr rahey hain.
suraksha.
phytosterol kaa surakshit upayog kaa ack lamba itihas haye, joe cytellin seey judaa huaa haye, 1954 seey 1982 taka sanyukt raajya america mein vipanan kiye gaye phytosterol kii dawa kii taiyari. phytosterol asters ney aam taur parr sanyukt raajya america mein surakshit (grass) sthiti key roop mein maanyata praapt kii haye. 2000 mein europeeya sangh key bajar mein pesh kiye jaane key baad phytosterol yukt karyatmak khaadya padaarth launch key baad kii nigrani key adheen they, aur koee apratyaashit dushprabhaav report naheen kiye gaye they.
phytosterol kii khapat key sambandh mein ack sambhaavit suraksha chinta phytosterolemia key rogiyon mein haye, ack durlabh aanuvanshik vikaar jisake parinamswarup rakt paudhe key sterol key star mein 50 seey 100 gunaa vriddhi hoti haye aur yeh coronary atherosclerosis key teji seey vikas seey judaa hotaa haye. phytosterolemia koo aeye. bee. see. jee. 5/jee. 8 protein mein utparivartan seey jodaa gayaa haye joe kramshah enterocytes aur hepatocytes seey paudhe key sterol koo lumen aur pitt nalikaon mein pump karate hain. rakt mein paadap sterol kaa star sakaratmak, nakaratmak yaa see. vee. dee. jokhim seey judaa naheen dikhaaya gayaa haye, joe adhyayan kii gaee aabaadi parr nirbhar kartaa haye.
paadap sterol aur see. vee. dee. yaa see. aich. dee. jokhim key beach kaa sambandh jatil haye kyonki phytosterol kaa star collestroll avashoshan koo darshaata haye. (collestroll avashoshan key liye ack marker key roop mein phytosterol dekhein).
sterol banaam stanol.
collestroll koo cumm karane key liye paadap sterol aur paadap stanol kii samkaksh kshamata aur suraksha ack germ bahas kaa vishay banaa huaa haye. naidaanik parikshanon mein sir-seey-sir kii tulanaa mein, paudhe key sterol aur stanol collestroll key star koo samaan roop seey cumm karate hue dikhaae gaye hain. 1. 0 seey 2.5 graam/dinn kii khuraak parr seedhe paudhe key sterol kii tulanaa karane vaale 14 yaadrichhik, niyantrit parikshanon key metaa-vishleshan mein kull collestroll, ell. dee. ell. collestroll, aich. dee. ell. collestroll, yaa triglyceride key star parr dou roopon key beach koee antar naheen dikhaaya gayaa. paadap sterol yaa stanol kii uchch khuraak (> 4 graam/dinn) koo dekhane vaale pareekshan bahut seemit hain, aur paadap sterol kii uchch khuraak kii tulanaa paadap stanol seey karane key liye abhee taka koee bhee puuraa naheen huaa haye.
sterol banaam sterol key baare mein bahas. stenol suraksha unake alag-alag aanton key avashoshan aur parinamswarup plasma sandrata parr kendrit haye. phytostenol mein phytosterol (0.4-5%) kii tulanaa mein cumm anumaanit aant avashoshan darr (0.02-0.3%) hoti haye aur isake parinamswarup rakt phytostenol kii sandrata aam taur parr phytosterol kii sandrata seey cumm hoti haye.
shodh.
phytosterol fefde, pett, andashay aur stun cancer key saath-saath brihadantra aur prostate cancer koo rokane kii unaki kshamata key liye praarambhik shodh key tahat hain.
paudhon mein kaary.
sterol sabhi eukariotes key liye aavashyak hain. pashu aur kavak koshikaon key vipareet, jinamen kewal ack pramukh sterol hotaa haye, paadap koshikaaen sterol mishran kii ack shrinkhala koo sanshleshit karati hain jisamen citosterol aur stigmasterol pramukh hotey hain. citosterol standhari koshika jhilli mein collestroll key samaan tareeke seey jhilli kii taralata aur pargamyata koo niyantrit kartaa haye. paadap sterol jhilli-baddh enzymon kii gatividhi koo bhee sanshodhit curr sakate hain. phytosterol tapman key liye paudhe key anukoolan aur rogjanakon key khilaf paudhe kii pratiraksha seey bhee judey hue hain.