
perm

perm ack procariotic actin homolog haye joe cytokinesis seey pahale chhad key aakar key bacteria key vipareet chhoron parr aar1 plasmid kii pratiyon koo chalaane key liye bull pradaan kartaa haye.
perm ack monomer haye joe aar1 plasmid key dna mein encode kiya jaataa haye aur mezban koshika key ribosome dwara nirmit hotaa haye. koshika dravya mein yeh swatah hii chhote taaron koo polymerise kartaa haye joe yaa tou paarr yaa hydrolyse seey judate hain. paarr perm koo sthir kartaa haye aur ise hydrolysing seey rokta haye. ack baar donon siron parr paar dwara bandhe jaane key baad, monomer ikaaiyaan perm key siron seey judati rahati hain aur parinami pratikriya aar1 plasmid koo koshika key vipareet siron parr dhakelati haye.
vibhinn jeevaanu plasmid key keetanu vishvasaniya plasmid viraasat koo banaae rakhane key liye dou yaa chaar taaron vaali aashcharyajanak roop seey vividh pechdar sanrachanaaen banaa sakate hain.
kaarravaai.
inn vitro mein parm monomer koo atp aur gtp donon key saath bahulak banaate hue dekhaa gayaa haye, lekin popp aur anya dwara prayog kiye gaye hain. aisaa prateet hotaa haye kii pratikriya jee. tii. pee. koo "pasand" karati haye aur jee. tii. pee. nucleotide haye joe koshika mein mahatvapurna yogdan detaa haye. iss lekh key shesh bhaag key liye jee. tii. pee. koo sakriya nucleotide maanaa jaayega, halanki kaee prayogon mein isake bajaay aeye. tii. pee. kaa upayog kiya gayaa haye.
jaise-jaise yeh bahulak hotaa haye, paam jee. tii. pee. koo baandhata haye aur hydrolyse kartaa haye. vartamaan pramukh vishvaas yeh haye kii jall apghataniya seey rokane key liye perm bahulak taaron key siron parr jee. tii. pee. kii "topi" kii aavashyakta hoti haye. halanki jee. tii. pee. koo sanlagnata key baad paam ikaaiyon dwara hydrolyse kiya jaataa haye, yeh maanaa jaataa haye kii plasmid koo chalaane vaali oorjaa paam monomer sandrata kii gibb mukt oorjaa seey praapt hoti haye, naa kii jee. tii. pee. hydrolysis seey jaari oorjaa seey. jee. tii. pee. sandrata kii parwah kiye binaa aage badhane key liye pratikriya key liye sanlagnak honey vaale chhoron parr perm monomer aur polymer kii sandrata koo santulan seey baahar rakhaa jaanaa chaahiye.
ack baar jaba paam ney plasmid koo koshika key vipareet chhoron parr dhakel diyaa haye tou bahulak teji seey apghatit hoe jaataa haye-monomer ikaaiyon koo koshika dravyamaan mein lautaata haye.
sanrachana.
jee. tii. pee. nucleotide koo baandhane seey pahale perm monomer ikai gair-karyatmak hoti haye. ack baar jee. tii. pee. koo baandh diye jaane key baad yeh badhate tantu key anta mein sanlagn hoe sakata haye. kissy bindu parr lagaav key baad perm jee. tii. pee. koo hydrolyse kartaa haye joe jee. dee. pee. bunn jaataa haye aur jaba taka bahulak strand barkarar rahata haye taba taka perm upa-ikai mein rahata haye. perm ack baaen haath kii helix sanrachana banaata haye.
garner aur campbelle dwara kiye gaye ack adhyayan ney sujhaav diyaa haye kii bahulak kii sthirata banaae rakhane key liye paam strand key anta mein ikai mein jee. tii. pee. baadhya honah chaahiye. yadi kissy ack chhor parr jee. dee. pee. baadhya sanskaran haye tou bahulak strand bahut jaldi apani ghatak monomer ikaaiyon mein apghatit hoe jaataa haye. yeh unake prayog dwara sujhaaya gayaa haye jisamen way badhate hue paam bahulak taaron koo kaatate hain joe aeye. dee. pee. baadhya chhoron koo ujagar karate hain. ack baar strand koo jaldi seey hydrolysed curr lein.
gatishil asthirta.
gatishil asthirta koo sthir vistaar aur teji seey chhote honey key charanon key beach ack bahulak key parivartan key roop mein varnit kiya gayaa haye. yeh prakriya eukariotic sookshm nalikaon key kaary key liye aavashyak haye. perm mein, gatishil asthirta "bachaav" yaa ack chhote charan seey vaapas vistaar charan mein switch bahut cumm dekhaa gayaa haye, aur kewal taba jaba aeye. tii. pee. nucleotide kaa upayog kiya jaataa haye. unbound perm filaments 1.5-2 microne kii ausat lambai key saath paae jaate hain, jaba perm monomer sandrata 2 microne yaa usase adhik hoti haye. perm aur eukariotic sookshm nalikaon kii gatishil asthirta koo abhisari vikas kaa ack udaaharan maanaa jaataa haye.
ell
jaba yeh koshika dravya mein maujood hotaa haye tou paam swatah hii chhote bahulak khand banaata haye. yeye khand aar1 plasmid key liye bahut kushalata seey "khoj" karane kaa kaam karate hain, aur polymerisation key liye perm monomer ikaaiyon kii anukool sandrata bhee banaae rakhate hain.

