
phosphorylcoline

phosphorylcoline (sankshipt roop mein chop) kuchh phospholipids kaa hydrophilic dhruviya sheersh samooh haye, joe ack chhote, sakaratmak aaveshit collin samooh seey bandhe nakaratmak aaveshit phosphat seey banaa haye. phosphorylcoline platelet-sakriya karane vaale kaarak kaa hissa haye; phospholipid phosphatidilcoline aur sphingomelin, jhilli kaa ekmatra phospholipid joe glycerol reedh key saath naheen banaaya gayaa haye. kuchh enzymon dwara, jaise kii kuchh phospholipase aeye2, aar. bee. see. kii tarah koshika jhilli kaa upchaar, phosphorylcholine bhaag koo baahari jaleey charan key sampark mein laataa haye, aur iss prakaar pratiraksha pranali dwara pehchaan key liye sulabh hotaa haye. phosphorylcholine key khilaf antibody praakritik roop seey honey vaale auto antibody hain joe cd5 +/bee-1 bee koshikaon dwara banaae jaate hain aur jinhen gair-rogjanak auto antibody key roop mein sandarbhit kiya jaataa haye.
thrombus pratirodhi stent.
interventional cardiology mein, phosphorylcholine kaa upayog ack synthetic polymer-adharit coating key roop mein kiya jaataa haye, jise coronary dhamani restinosis kii ghatana koo rokane key liye dawa-alluting stent parr lagaaya jaataa haye. stent key upayog key liye iss drishtikon kaa pahala anuprayog hayward, chapman aur anya key prayason seey vikasit huaa.", jinhone dikhaaya kii erythrocyte dwi parat kii baahari satah kaa phosphorylcholine ghatak gair-ghanastra thaa. 2002 taka, nange dhaatu stent praudyogikiyon kii tulanaa mein deerghakaalik roop seey koee spasht hanikarak prabhaav naheen rakhane vaale rogiyon mein 120,000 seey adhik phosphorylcholine-lepit stent lagaae gaye hain.
phosphorylcoline bahulak-adharit dawa-alluting stent.
dawa-eluting stent (days) kaa upayog interventional cardiologist dwara kiya jaataa haye, joe coronary dhamani roga key rogiyon parr kaam karate hain. gubbare kii angioplasty key madhyam seey stent koo dhamani mein daala jaataa haye. yeh coronary dhamani key vyaas koo failaayega aur iss charan mein ise sthir rakhega taaki rakt key thakkon (atherosclerosis) key jokhim key binaa dhamani key madhyam seey adhik rakt pravaahit hoe. 
phosphorylcholine kaa upayog days key bahulak-adharit coating key roop mein kiya jaataa haye kyonki isaki aanvik rachana satah kii jaiv-sangatata mein sudhaar karati haye aur soojan yaa ghanastrata paida karane key jokhim koo cumm karati haye. stent key bahulak coatings joe dhamani vahika kii deewaar taka anty-proliferative dawa joterolimus pahunchaate hain, inn chikitsa upkaranon key ghatak hain. dhamani mein zotarolimus key lakshit sthaaniya vitaran key liye, dawa koo ack methacrylate-adharit coppolymer mein shamil kiya jaataa haye jisamen phosphorylcoline kaa ack synthetic roop shamil hotaa haye. biomimicry kaa yeh upayog, yaa jeev vigyaan mein praakritik roop seey honey vaale polymer kaa upayog karane kaa abhyaas, nyuntam thrombus nikshepan key saath ack parat pradaan kartaa haye aur dhamani vahika kii deewaar key dair seey upchaar parr koee pratikool naidaanik prabhaav naheen padata haye. coating naa kewal gair-ghanastra haye, balki yeh anya visheshtaon koo bhee pradarshit kartaa haye joe deerghakaalik pratyaropan key liye chikitsa upkaran parr aisee samagri koo lagu karate samay maujood honey chaahiye. inmein sthaayitva, nigamit dawa key rasayan vigyaan key prati tatasthata aur maanak tarikon kaa upayog karke nasbandi kii kshamata shamil haye joe dawa kii sanrachana yaa dakshata koo prabhaavit naheen karate hain.