
amyloid-beeta poorvavarti protein sraav

sraav enzyme hotey hain joe koshika jhilli mein antarnihit ack lambe protein key tukadon koo "snip" karate hain. koshika mein anya bhoomikaon key beach, sraav protein koo teen tukadon mein vibhajit karane key liye emiloid-beeta agradoot protein (aip) parr kaary karate hain. beeta-sraav 1 (bases) aur gaama-sraav (γ-sraav) dwara kramik daraar amyloid-beeta peptide tukade kaa utpaadan karati haye joe alzheimer roga seey prabhaavit mastishk mein amyloid plake naamak guchhe mein ekatrit hoti haye. yadi alfa-sraav (α-sraav) bases key bajaay pahale aip parr kaary kartaa haye, tou koee emiloid beeta naheen banata haye kyonki α-sraav bases kii tulanaa mein koshika kii satah key karib ack lakshit protein anukram koo pahachaantaa haye. ack α/γ daraar anukram dwara gathit gair-rogjanak madhya tukade koo p3 kahaa jaataa haye.
sanrachana.
teen sraavon kii sanrachana vyaapak roop seey bhinn hoti haye.
kaary.
alzheimer key rogjanan mein unaki bhagidari key alawa, inn proteins kii koshika mein anya karyatmak bhoomikaaen bhee hain.
γ-sraav transmembrane receptor notch dwara vikasatmak sanket mein ack mahatvapurna bhoomika nibhaata haye, joe ack pratilekhan kaarak key roop mein kaary karane key liye koshika naabhik kii yatra karane key liye notch kii koshika-dravyamaan poonchh koo mukt kartaa haye.
halanki bases kaee transmembrane protein key baahya koshikiya kshetron koo vibhajit kartaa haye, lekin iska shaaririk kaary agyaat haye.

