sialodecin

sialodecin macrophage kii satah parr paaya jaane vaalaa ack koshika asanjan anu haye. yeh pliha, yakrit, lymph node, asthi majja, brihadantra aur fefadon key macrophage parr vishesh roop seey uchch matra mein paaya jaataa haye. rheumatoid arthuritis key rogiyon mein bhee, prabhaavit ootakon key macrophage parr protein badee matra mein paaya gayaa haye. ise aaee-type lectin key roop mein paribhaashit kiya gayaa haye, kyonki isamen 17 immunoglobulin (aaee. jee.) domen (ack parivartaniya domen aur 16 sthir domen) hotey hain, aur iss prakaar yeh immunoglobulin super family (aaee. jee. aiss. aff.) seey bhee sambandhit haye. sialodecin kuchh anuon seey judataa haye jinhen sialik acid kahaa jaataa haye. iss bandhan prakriya key dauran ack atyadhik sanrakshit arginine avashesh (vee-sett domen seey 3 '-sialilectose taka) aur sialik acid key carboxylate samooh key beach ack namak pull (protein) banata haye. choonki sialodecin apane aine-terminal igv-domen key saath sialik acid koo baandhata haye, isaliye yeh sigleck parivaar kaa bhee sadasya haye. sialodecin key vaikalpik naamon mein sigleck-1 aur see. dee. 169 (vibhedan kaa samooh 169) shamil hain.
sialodecin mukhya roop seey neutrophil koo baandhata haye, lekin monocytes, praakritik ghaatak koshikaon, bee koshikaon aur cytotoxic tii koshikaon key ack upasamuchchay koo unaki satahon parr ligand mein sialik acid anuon key saath baatchit karke bhee baandh sakata haye.
sialodecin (see. dee. 169) positive macrophage, messenkimal stame koshikaon aur beeta-adrenergic neurons key saath, asthi majja mein hematopoetic stame cell aalaa banaate hain. हैं। + macrophage vibhinn koshikaon key beach sanket dete hain aur hematopoetic stame cell koo sthaan mein banaae rakhane koo badhaava dete hain.

