
jaid. pee. 4

jonaa pellucida shukranu-badhyakari protein 4, jdp-4 yaa avillesin, jiska naam isake khojkarta manual avilles sanchez key naam parr rakhaa gayaa haye, ack protein haye jise manushyon mein "jdp4" jeane dwara kootbaddh kiya jaataa haye.
kaary.
jonaa pellucida ack baahya koshikiya matricks haye joe andkosh aur praarambhik bhroon koo gherta haye. yeh mukhya roop seey teen yaa chaar glycoprotein seey banaa hotaa haye joe nishechan aur poorv pratyaropan vikas key dauran vibhinn karyon key saath hotaa haye. navjat protein mein ack aine-terminal signal peptide anukram, ack sanrakshit jonaa pellucida-jaisa domen, ack sarvasammati seey furin cleavage site aur ack see-terminal transmembrane domen hotaa haye. yeh parikalpana kii gaee haye kii furin vichhedan key parinamswarup baad mein jonaa pellucida matricks mein shamil karane key liye plasma jhilli seey paripakva protein kii rihaai hoti haye. haalaanki, iss prakriya mein furin daraar kii aavashyakta choohe key adhyayan key aadhar parr vivadaspad bunny hui haye.
pahale, iss jeane koo jdp1 yaa jdpb key roop mein sandarbhit kiya gayaa haye aur mouse jdp1 key samaan kaary karane key liye socha gayaa haye. haalaanki, mouse jdp1 key liye uchch samaantaa aur gunasutra samanvaya key saath ack maanav jeane koo prateek jdp1 saunpa gayaa haye aur iss jeane koo prateek jdp4 saunpa gayaa haye.