
carbamoil phosphat synthetase i

carbamoil phosphat synthetase i ack ligage enzyme haye joe mitochondria mein sthit haye joe euria key utpaadan mein shamil haye. carbamoil phosphat synthetase i (cps1 yaa cpsi) ack amonia anu koo bicarbonate key anu mein sthanantarit kartaa haye jise aeye. tii. pee. key anu dwara phosphorylated kiya gayaa haye. isake parinamswarup carbamate koo phir aeye. tii. pee. key ack anya anu key saath phosphorylated kiya jaataa haye. carbamoil phosphat kaa parinami anu enzyme chhod detaa haye.
sanrachana.
ee mein. kolai "ekal see. pee. aiss. joe see. pee. aiss. aaee. aur see. pee. aiss. aaee. key karyon koo puuraa kartaa haye, ack chhote upa-ikai key saath ack heterodymer haye aur aakar mein lagbhag 382 aur 1073 emino acid avasheshon key saath ack badaa upa-ikai haye, halanki standhaariyon (aur anya kasheruki) mein see. pee. aiss. aaee. protein koo ack ekal jeane dwara kootbaddh kiya jaataa haye. chhote upa-ikai mein amonia aur glutamate banaane key liye glutamine key bandhan aur demination key liye ack sakriya sthal hotaa haye. badee upa-ikai mein dou sakriya sthal hain, ack carboxifosphate key utpaadan key liye aur doosara carbamoil phosphat key utpaadan key liye. badee upa-ikai key bheetar dou domen (bee aur see) hain jinamen seey pratyek aeye. tii. pee.-grasp parivaar kii ack sakriya site haye. dou upa-ikaaiyon koo jodane vaali ack tarah kii surang haye, joe amonia koo chhote upa-ikai seey badey upa-ikai taka leey jaati haye.
tantra.
see. pee. aiss. aaee. mein honey vaali samagr pratikriya haih
2atp + hco3 − + nh4 + → 2adp + carbamoil phosphat + paaee
iss pratikriya koo teen alag-alag charanon mein honey key baare mein socha jaa sakata haye.
viniyaman.
see. pee. aiss. aaee. koo aine-acetylglutamate dwara viniyamit kiya jaataa haye joe see. pee. aiss. 1. aine. aeye. jee. key ack baadhya alausteric sakriyak key roop mein kaary kartaa haye, domen ell4 key liye baadhya karke, aeye-loop mein parivartan koo trigger kartaa haye aur aarg1453 mein jisake parinamswarup domen ell3 key teang-loop key saath baatchit badalati haye, joe poori tarah seey aeye. pee. oh. roop mein ack beeta-hairpin seey ligand-bound roop mein ack vistrit loop mein punargathit hotaa haye. iss antim roop mein, tii-loop surang-loop aur ell1 domen key tii-loop key saath bhee baatchit kartaa haye, iss prakaar sakriya karane vaali jaankaari koo bicarbonate-phosphorillating domen mein sthanantarit kartaa haye. naag key saath yeh antahkriya aur ack nucleotide key saath doosari antahkriya, see. pee. aiss. aaee. key sakriya roop koo sthir karati haye.
iss ligand kii aavashyakta nitrogen kii uchch sandrata koo bhee jodati haye, joe kii naig kaa utpaadan karane key liye glutamate aur arginine kii adhikta mein parilakshit hoti haye, iss atiriktata koo saaf karane key liye cpsi gatividhi mein vriddhi key liye.
chayapachaya.
see. pee. aiss. aaee. protein aur nitrogen chayapachaya mein mahatvapurna bhoomika nibhaata haye. ack baar jaba amonia koo glutamine yaa glutamate key madhyam seey mitochondria mein laaya jaataa haye, tou carbamoil phosphat banaane key liye phosphat samooh key saath bicarbonate mein amonia jodana see. pee. aiss. aaee. kaa kaam hotaa haye. carbamoil phosphat koo phir antatah euria banaane key liye euria chakr mein daal diyaa jaataa haye. phir euria koo rakt pravaah mein aur nispandan key liye gurde mein aur visarjan key liye mootrashay mein vaapas sthanantarit kiya jaa sakata haye.
sambandhit swaasthya samasyaaen.
see. pee. aiss. aaee. seey sambandhit mukhya samasya aanuvanshiki-adharit haye. kabhi-kabhi aanuvanshik code mein utparivartan key kaaran shareer paryaapt see. pee. aiss. aaee. kaa utpaadan naheen kartaa haye, jisake parinamswarup protein aur nitrogen kaa kharaab chayapachaya hotaa haye, saath hii shareer mein amonia kaa uchch star hotaa haye. yeh khatarnak haye kyonki amonia shareer key liye atyadhik vishaakt haye, vishesh roop seey tantrika tantra key liye, aur isake parinamswarup bauddhik akshamta aur daure hoe sakate hain.

