
francisi dhwaj model

francisi dhwaj model ack morphogen kii ack vaichaarik paribhasha haye, jise 1960 key dashak mein luis volpert dwara varnit kiya gayaa thaa. ack morphogen koo ack sanket anu key roop mein paribhaashit kiya gayaa haye joe morphogen sandrata parr nirbhar vishisht koshikiya pratikriyaon kaa utpaadan karane key liye koshikaon parr seedhe kaary kartaa haye (kramik preran key madhyam seey naheen). praarambhik vikas key dauran, morphogen pravanata alag-alag sthaanik crum mein vibhinn prakaar kii koshikaaen utpann karate hain. francisi dhwaj pratiroopan aksar dusaron key saath sanyojan mein paaya jaataa haih kasheruki anga vikas kaee phenotype mein seey ack haye joe ack poorak pattern (iss mamle mein turing pattern) key saath ativyaapi francisi dhwaj pratiroopan koo pradarshit kartaa haye.
avalokan.
francisi dhwaj model mein, francisi dhwaj kaa upayog koshika vibhedan parr ack morphogen key prabhaav kaa pratinidhitva karane key liye kiya jaataa haih ack morphogen ekagrata key aadhar parr koshika avasthaon koo prabhaavit kartaa haye, inn avasthaon koo francisi dhwaj key vibhinn rangon dwara darshaaya jaataa haih uchch sandrata ack "neela" jeane koo sakriya karati haye, cumm sandrata ack "safed" jeane koo sakriya karati haye, jisamen "laal" aavashyak sandrata seema seey neeche kii koshikaon mein default sthiti key roop mein kaary kartaa haye.
francisi dhwaj model koo pramukh "drosophila" jeevvigyaani, peater laurence dwara samarthit kiya gayaa thaa. christian naslen-wolhard ney pahale morphogen, "bicoid" kii pehchaan kii, joe "drosophila" syncitial bhroon mein ack dhaal mein maujood pratilekhan karakon mein seey ack haye. gairi strull aur stephen kohain kii dou prayogshalaon ney taba pradarshit kiya kii ack sraavit sanket protein, decapentaplegic (vikas kaarak beeta koo badalane kaa "drosophila" homolog), "drosophila" vikas key baad key charanon key dauran ack morphogen key roop mein kaary kartaa haye. padaarth ootak vikas key swaroop koo niyantrit kartaa haye aur vishesh roop seey, ack ootak key bheetar vibhinn vishesh prakaar kii koshikaon kii sthiti koo niyantrit kartaa haye. yeh ack sthaaniya srot seey failata haye aur ack vikaasheel ootak mein ack sandrata pravanata banaata haye.
prasiddh morphogen mein shamil hainh decapentaplegic/parivartansheel vikas kaarak beeta, hezhog/sonic hezhog, wingless/doubleu. aine. tii., epidermal vikas kaarak, aur fibroblast vikas kaarak.
kuchh sabse shuruati aur sabse achche adhyayan kiye gaye morphogen pratilekhan kaarak hain joe praarambhik "drosophila melanogaster" (phal makkhi) bhroon key bheetar failate hain. haalaanki, adhikansh morphogen sraavit protein hotey hain joe koshikaon key beach sanket dete hain.
morphogen koo rasayanik roop seey naheen, balki vaichaarik roop seey paribhaashit kiya jaataa haye, isaliye retinoic acid jaise saral rasayan bhee morphogen key roop mein kaary curr sakate hain.
kathinaaiyaan.
francisi dhwaj model kaa aadhar yeh vichaar haye kii ack morphogen swaayatt roop seey ack dhaal banaata haye jisamen alag-alag koshikaaen dhaal kii sandrata koo padhati hain. koshikaaen taba ack vishisht vibhedan key saath dhaal key ack vishisht star parr pratikriya karati hain taaki usa sthiti seey mell khaa sakey joe dhaal ingit kartaa haye kii way hain. halanki vyaapak roop seey roopjanan koo samajhane key liye ack mahatvapurna model key roop mein sweekaar kiya gayaa haye, lekin ise sabhi vikasatmak jeevvigyaani dwara saarvbhaumik roop seey sweekaar naheen kiya gayaa haye. morphogenesis key sabhi dhaal adharit model key saath kathinaaiyon kii vyaapak roop seey natally aur richard gorden dwara sameeksha kii gaee thee aur isamen saat vishisht bindu shamil hainh

