
edward markote

edward markot austin mein texas vishvavidyalaya mein jaiv rasayan key professor hain, joe aanuvanshiki, proteomics aur jaiv soochana vigyaan mein kaam curr rahey hain. markote ack computational jeevvigyaani kaa ack udaaharan haye joe jaiv soochana vigyaan-adharit bhavishyavaniyon koo maanya karane key liye prayogon parr bhee nirbhar kartaa haye.
shiksha aur pada.
markotte kii snaatak shiksha austin mein texas vishvavidyalaya mein hui thee, jahan unhone bee. aeye. praapt kiya.aiss. 1990 mein sookshm jeev vigyaan mein. unhone apani ph. dee. praapt kii.dee. 1995 mein austin mein texas vishvavidyalaya seey jaiv rasayan mein, aur professor david eisenberg key saath yuu. tii. austin aur california vishvavidyalaya, loss angils donon mein apane postdoctoral kaam kiya. markote 2001 seey yuu. tii. austin mein professor hain.
shodh.
markotte kaa pramukh shodh yogdan jaiv soochana vigyaan, proteomics, system biology aur synthetic biology key kshetron mein haye.
jaiv soochana vigyaan aur pranali jeev vigyaan.
praarambhik kaary mein, markot aur sahyogiyon ney kissy bhee jatil jeev (yeast sacromyces serevisia) mein protein key beach karyatmak sambandhon kaa pahala genome-scale maanchitra banaaya, ack aisaa drishtikon jisane unhein sabhi gair-vishishteekrit yeast protein key aadhe seey adhik kaary kii bhavishyavani karane kii anumati dee. markote ney proteins key beach karyatmak antahkriya kii pehchaan karane key kaee tareeke bhee vikasit kiye, jinamen phylogenetic profiling, roseta stone jeane fusion, aim. aar. aine. aeye. saha-abhivyakti aur darpan vriksh drishtikon shamil hain.
2010 mein, markote aur unake sahyogiyon ney phenotype key aadhar parr gahare samroopata key mamalon kii pehchaan karane key liye ack algorithm kii pehchaan kii.
proteomics.
proteomics key kshetra mein, markote key yogdan mein maanav protein antahkriya network key praarambhik sanskaranon kaa vikas aur 7,000 seey adhik maanav protein antahkriyaon kaa maanchitran shamil haye. markot aur unake sahyogiyon ney protein abhivyakti, upkoshikiya sthaan aur kaary key uchch-pravaah maapan key liye chittidaar koshika sookshm-aarey takneek vikasit kii, dravyamaan varnakramiya detta kaa vishleshan karane key liye algorithm vikasit kiye, dravyamaan varnakramiya proteomics detta key liye ack khula pahunch databases shuru kiya, aur ack proteom-wide paimaane parr nirpeksh protein matratmakta key liye sheersh vidhi vikasit kii. sheersh, markot aur sahyogiyon kaa upayog karke pradarshit kiya kii nichale eukariot mein protein kii prachurta mukhya roop seey aim. aar. aine. aeye. key star dwara nirdhaarit kii jaati haye, jabaki maanav protein kii prachurta lagbhag samaan roop seey pratilekhan aur post-transcription viniyaman dwara nirdhaarit kii jaati haye.