polycomb-samooh protein

polycomb-group protein (pee. see. jee. protein) protein parisaron kaa ack parivaar haye joe pahali baar phal makkhiyon mein paaya gayaa haye joe chromatin koo iss tarah seey phir seey banaa sakata haye kii jeane kaa epigenetic silencing hotaa haye. polycomb-samooh protein phal makkhiyon ("drosophila melanogaster") mein bhroon vikas key dauran chromatin sanrachana key modulan key madhyam seey hocks jeane koo shaant karane key liye jaane jaate hain. way apana naam iss tathya seey praapt karate hain kii pee. see. jee. kaary mein kamee kaa pahala sanket aksar peechhe key pairon kaa purvakaal kii or ack homotic parivartan hotaa haye, jisamen bristal kaa ack visheshta kanghi jaisa sett hotaa haye.
keeton mein.
drosophila" mein, trithorax-samooh (tii. aar. aiks. jee.) aur polycomb-samooh (pee. see. jee.) protein virodhi roop seey kaary karate hain aur gunasutra tatvon key saath baatchit karate hain, jinhen cellular memori module (see. aim. aim. aiss.) kahaa jaataa haye. trithorax-samooh (tii. aar. aiks. jee.) protein jeane abhivyakti kii sakriya sthiti koo banaae rakhate hain jabaki polycomb-samooh (pee. see. jee.) protein iss sakriyan kaa ack damankari kaary key saath virodh karate hain joe kaee koshika peedhiyon mein sthir hotaa haye aur kewal germaline vibhedan prakriyaon dwara door kiya jaa sakata haye. polycomb jeane complexes yaa pee. see. jee. silencing mein cumm seey cumm teen prakaar key multiprotein complexes polycomb repressive complexes 1 (pee. aar. see. 1), pee. aar. see. 2 aur fork hotey hain. yeye parisar apane damankari prabhaav koo puuraa karane key liye ack saath kaam karate hain. pee. see. jee. protein vikasatmak roop seey sanrakshit hotey hain aur cumm seey cumm dou alag-alag protein parisaron mein maujood hotey hain; pee. see. jee. damankari parisar 1 (pee. aar. see. 1) aur pee. see. jee. damankari parisar 2-4 (pee. aar. see. 2/3/4). pee. aar. see. 2. histone histone aich3 parr lycine 27 key trimethyltion koo utprerit kartaa haye, jabaki pee. aar. see. 1 mono-sarvavyaapi lycine 119 119. (aich2aeye. bee. 1) parr histone histone koo utprerit kartaa haye.
standhaariyon mein.
standhaariyon mein polycomb samooh jeane abhivyakti vikas key kaee pahaluon mein mahatvapurna haye jaise homotic jeane viniyaman aur aiks gunasutra nishkriyata, aiks. see. aaee. yaa bhroon stame cell swa-navikaran key master niyaamak, accist aar. aine. aeye. dwara nishkriya aiks. mein bharti kiya jaa rhaa haye. bee. aim. aaee. 1 polycomb ring finger protein tantrika stame cell swa-navinikaran koo badhaava detaa haye. pee. aar. see. 2 jeane mein murine null utparivarti bhroon lethal hotey hain jabaki adhikansh pee. aar. see. 1 utparivarti jeevit homotic utparivarti hotey hain joe perinatally marr jaate hain. isake vipareet pee. see. jee. protein kii atee abhivyakti kaee prakaar key cancer kii gambhirta aur aakramansheelta key saath sambandhit haye. standhari pee. aar. see. 1 core parisar drosophila key samaan hain. polycomb bee. aim. aaee. 1 syaahi 4 locus locus, (pee16ink4aeye koo niyantrit karane key liye jaanaa jaataa haye.
dwi-varna chromatin sthalon parr polycomb-samooh protein kaa viniyaman swai/aiss. aine. aff. parisaron dwara kiya jaataa haye, joe aeye. tii. pee.-nirbhar nishkasana key madhyam seey polycomb parisaron key sanchay kaa virodh karate hain.
paudhon mein.
physcometrella pattense" mein pee. see. jee. protein phee vishesh roop seey nishechit andaa koshika jaisi stame koshikaon mein vyakt kiya jaataa haye. nishechan key turant baad yuva bhroon mein phee jeane nishkriya hoe jaataa haye. polycomb jeane phee kaaee key physcometrella pattense kii nishechit andaa koshikaon mein vyakt kiya jaataa haye aur vikasit dwigunit sporophyte mein nishechan key baad abhivyakti bund hoe jaati haye.
yeh dikhaaya gayaa haye kii standhaariyon key vipareet koshikaon koo ack alag sthiti mein rakhane key liye pee. see. jee. aavashyak haye. natijatan, pee. see. jee. kii haani vibhedan kaa kaaran banati haye aur bhroon key vikas koo badhaava detee haye.
polycomb-samooh protein bhee foolon key sthaan see jeane koo chup karakar foolon key niyantran mein hastakshep karate hain. yeh jeane maarg kaa ack kendriya bhaag haye joe paudhon mein foolon koo rokta haye aur sardiyon key dauran isaki khamoshi koo paudhe key vernalisation mein hastakshep karane vaale mukhya karakon mein seey ack honey kaa sandeh haye.

