
reeb

pratilekhan kaarak rableb ack protein haye jise manushyon mein "rableb" jeane dwara kootbaddh kiya jaataa haye.
antahkriyaaen.
aar. ell. bee. koo aine. aff. key. bee. 2, aine. aff. key. bee. 1 aur see. 22orph25 key saath antahkriya karate hue dikhaaya gayaa haye.
sakriyan aur kaary.
vishram koshikaon mein, koshika-dravya mein aine. aff.-key. bee. poorvavarti protein pee. 100 dwara rableb koo alag kiya jaataa haye. lymphotoxin beeta-receptor (ell. tii. bee. aar.), baif-aar., see. dee. 40 aur rank sahit tii. aine. aff.-aar. superfamily sadasyon kaa ack chuninda samooh gair-canonical aine. aff.-key. bee. maarg koo sakriya kartaa haye. iss maarg mein, nick pee100 key pee52 mein prasanskaran koo uttejit kartaa haye, joe kii rableb key saath milkar naabhik mein rablebah pee52 nf-kebi heterodymer key roop mein dikhaai detaa haye. rablebah pee52 homostatic lymphochines abhivyakti koo sakriya kartaa haye, joe lymphoid organogenesis kaa nirdesh detaa haye aur maadhyamik lymphoid angon mein nishkapat lymphocyte kii taskari koo nirdhaarit kartaa haye.
haal key adhyayanon ney sujhaav diyaa haye kii karyatmak gair-canonical aine. aff.-key. bee. maarg koo canonical aine. aff.-key. bee. signalling dwara sanshodhit kiya jaataa haye. udaaharan key liye, gair-canonical maarg key ghatakon key sanshleshan, jaise kii ralab aur pee52, canonical aaee. key. 2-aaee. key. bee.-relaah pee50 signalling dwara niyantrit hotey hain. isake alawa, cellular parivesh key bheetar canonical aur gair-canonical diamer, jaise relaah pee 50 aur relebah pee 52, kii peedhi yaantrik roop seey aapas mein judee hui haye. inn vishleshanon seey pataa chalata haye kii ack ekikrit aine. aff.-key. bee. pranali network diamer yukt rille aur relabe donon key sakriyan koo aadhar banaata haye aur ack kharaab canonical maarg gair-canonical maarg key madhyam seey bhee ack aniyamit cellular pratikriya kaa kaaran banega.
sabse dilchasp baat yeh haye kii haal key ack adhyayan ney pehchaan kii haye kii tii. aine. aff.-prerit canonical signalling gair-canonical relabe koo nasht karati haih soojan vaale lymphoid ootakon mein pee52 gatividhi lymphocyte pravesh koo seemit karati haye. yaantrik roop seey, tii. aine. aff. ney ell. tii. bee. aar.-uttejit koshikaon mein nishkriya nick koo prerit kiya aur "aine. aff. key. bee. 2" aim. aar. aine. aeye. encoding pee. 100 key sanshleshan koo prerit kiya; yeye ack saath prabal roop seey asansaadhit pee. 100 koo jamaa karate hain, jisane relabe gatividhi koo cumm curr diyaa. soojan vaale lymphoid ootak mein lymphocyte pravesh koo nirdhaarit karane mein pee 100/aine. aff. key. bee. 2 kii bhoomika key vyaapak shaaririk nihitarth hoe sakate hain.