
stephen elge

stephen joseph elge (janm 7 agast, 1956) ack americi aanuvanshikeevid hain. way harvard medical school key aanuvanshiki vibhaag mein aur brigham aur mahila aspatal key aanuvanshiki vibhaag mein aanuvanshiki aur chikitsa key vartamaan gregor mendell professor hain. unakaa shodh dee. aine. aeye. kshati key liye eukariotic pratikriya key aanuvanshik aur aanvik tantra parr kendrit haye, aur dee. aine. aeye. kshati pratikriya (dee. dee. aar.) key khojkarta key roop mein jaanaa jaataa haye.
praarambhik jeevan aur shiksha.
elge kaa janm 1956 mein peris, ilinois mein huaa thaa. way 1974 mein peris hyee school seey snaatak karate hue badey hue bhee they. unhein bachpan seey hii rasayan vigyaan mein ruchi haye, ack rasayan vigyaan sett key liye dhanyavaad joe unaki daadi ney unhein diyaa thaa.
unhone rasayan vigyaan mein snaatak honey aur ack javic rasaayanagya banane kii ummeed karate hue ilinois arbana-shampen vishvavidyalaya mein pravesh kiya. elge ney shuru mein jeevan vigyaan key vishayon koo nazarandaj curr diyaa, jaba taka kii unhone apane teesare (yaa kanishth) varsh key dauran ingland key southampton vishvavidyalaya mein jeev vigyaan aur aanuvanshiki pathyakramon mein bhaag naheen liya. ilinois lautane key baad unhone jaiv rasayan kaa pathyakram liya, jisane unhein 1978 mein bsc praapt karane key baad massachusets praudyogiki sansthaan (mit) mein jeev vigyaan mein phd kaa adhyayan karane key liye prerit kiya. elge ney 1983 mein mit seey snaatak kiya.
carrier.
elge ney 1984 mein steinford vishvavidyalaya mein ack postdoctoral fellow key roop mein apane currier kii shuruat kii. davis kaa samooh. 1989 mein, way biochemistry mein sahayak professor key roop mein beller college off medicine mein chaley gaye, unhein 1993 mein associate professor aur 1995 mein poorna professor key roop mein padonnat kiya gayaa.
2003 mein, elge harvard medical school key aanuvanshiki vibhaag mein shamil hoe gaye.
vartamaan mein, elge harvard medical school key aanuvanshiki vibhaag mein aur brigham aur mahila aspatal key aanuvanshiki vibhaag mein aanuvanshiki aur chikitsa key gregor mendell professor hain. vaha whitehead sansthaan key salaahkaar vaigyaanikon key board aur "aanvik koshika" key salaahkaar board mein bhee baithate hain.
elge 1993 seey howard hugg medical institute mein ack janchkarta rahey hain.
shodh karein.
elge kaa shodh kaee kshetron mein faila huaa haye, jisamen koshika chakr, dee. aine. aeye. kii marammat aur rakt seey virus kaa pataa lagaana shamil haye.
unhone steinford vishvavidyalaya mein postdoctoral fellow key roop mein apane varshon key dauran dee. aine. aeye. marammat kaa adhyayan karna shuru kiya. elge ney galati seey khameer mein rnr2 jeane aur protein kii khoj kii, joe ribonucleotide reductage key parivaar seey sambandhit haye, aur paaya kii dna key kshatigrast honey parr isaki abhivyakti badh jaati haye. aar. aine. aar. 2, yaa homolog key maanav samkaksh, aar. aar. aim. 2 aur aar. aar. aim. 2 bee hain.
agale dashak mein, unhone khameer aur manushyon mein dee. aine. aeye. kshati pratikriya maarg mein shamil jeane aur protein kii khoj jaari rakhee. udaharanon mein khameer mein dunn1, meck1 aur tail1 shamil hain, (sambandhit maanav samroopata check2, aeye. tii. aar. aur aeye. tii. aim. hain) aur manushyon mein check1 aur check2 shamil hain.
koshika chakr anusandhaan mein, unake samooh ney 1993 mein koshika chakr jaanch chaukiyon parr dou mahatvapurna patra prakaashit kiye. bert woggelstein key samooh seey samanantar aur swatantra roop seey, unhone pee21 kii khoj kii aur visheshta dee, joe ack cycline-nirbhar kinnez avarodhak protein haye joe jee1/aiss sankraman koo avaruddh kartaa haye. unhone yeh bhee dikhaaya kii aar. bee. protein mitosis seey laker khameer mein madhya-jee1 charan taka pee. pee. 1aeye. key saath shaaririk roop seey judataa haye. beller college off medicine mein jaane key baad, elge ney cdk2 kii apani pehchaan kii soochana dee, ack protein jiska sakriyan koshikaon koo jee1 charan seey koshika chakr key aiss charan mein pargaman karane kii anumati detaa haye.
elge key samooh ney aff-boxes protein sanrachanaatmak rupankan kii bhee khoj kii, aur paaya kii yeh vishisht protein anukramon koo pahachaantaa haye aur protein koo ksharan key liye ubquitin key saath tagg kartaa haye. unhone protein ksharan mein aff-boxes kii kendriya bhoomika kii sahee bhavishyavani kii kyonki badee sankhya mein protein mein yeh rupankan haye.
2015 mein, elge key samooh ney worscan vikasit kiya, ack aisaa munch joe rogiyon mein rakt kii ack chhoti matra seey viral sankraman kaa pataa lagaata haye.
haal key varshon mein, elge ney apane shodh kshetra kaa vistaar karna jaari rakhaa haye. udaaharan key liye, unake samooh ney ack computational model kii soochana dee jisamen gunasutra parr kshetron key asamanya roop seey pravardhit honey kii sambhavana kii bhavishyavani kii gaee thee.
covid-19 mahamari key dauran, elge ney anuman lagaaya kii sanyukt raajya america ney kull 25 laakh varshon kaa jeevan khou diyaa haye.
vyaktigat jeevan.
elge kii shaadi mitzi kuroda seey hui thee, joe khud harvard medical school mein aanuvanshiki vibhaag mein professor they. way donon 2003 mein beller college off medicine seey harvard medical school chaley gaye.

