
supernostic

supernostic ack saralikrit double monoclonal antibody sandwich enzyme-linked immunosorbent parakh (elissa) haye joe rakt mein ghulansheel eurokinez plasminogen activator receptor (super) kii matra koo maapata haye. vibhinn sankraamak, soojan aur autoimmune rogon mein plasma kaa uchch star dekhaa gayaa haye. super ekagrata sakaratmak roop seey pratiraksha pranali key sakriyan star seey sambandhit haye. supernostic kaa upayog ack rogi key bheetar ack bimari kii gambhirta koo nirdhaarit karane key liye ack purvanuman upkaran key roop mein kiya jaa sakata haye, lekin iska upayog ack vishvasaniya naidaanik upkaran key roop mein naheen kiya jaataa haye, kyonki yeh ack rogi mein pratiraksha pratikriya kii gambhirta kaa pataa lagaa sakata haye, lekin usa vishisht bimari koo prakat naheen kartaa haye jisase rogi peedit hoe sakata haye. haal hii mein, sooper star mein vriddhi koo pranaaleegat soojan pratikriya syndrome (surr)/sepsis, hriday roga, prakaar 2 madhumeh, sankraamak roga, aich. aaee. vee., cancer tapedik, maleria, jeevaanu aur viral see. aine. aiss. sankraman, sandhishoth, multiple sclerosis aur samanya aabaadi mein mrityu darr key badhate jokhim seey judaa huaa dikhaaya gayaa thaa.
supernostic elissa kaa pradarshan karna.
supernostic elissa karane key liye super key liye uchch vishishtata vaale dou antibody kii aavashyakta hoti haye. rogi key rakt plasma key namoone mein jisme super kii ack agyaat matra hoti haye, usey spasht microtiter plate parr microwell parr sthir kiya jaataa haye aur ack pehchaan karane vaali antibody super key saath ack jatil banaati haye.
pratyek charan key beach plate koo kissy bhee protein key niptan key liye wash buffer seey dhoya jaataa haye joe vishesh roop seey plate parr kissy bhee kuein seey naheen judataa haye. antim dhone key charan key baad, plate koo ack drishya sanket kaa utpaadan karane key liye tii. aim. bee. substrate jodkar vikasit kiya jaataa haye, joe namoone mein super kii matra koo ingit kartaa haye. maapa gayaa avashoshan, maanak vakr seey moolyon key aadhar parr, namoone mein super kii sandrata (ng/ml) mein parivartit kiya jaa sakata haye. yeh star taba yeh sujhaav dey sakata haye kii rogi apani pratiraksha pranali key liye chunautiyon kaa saamana curr rhaa haye yaa naheen.
siddhant.
supernostic elissa ack saralikrit double monoclonal antibody sandwich parakh haye joe shareer mein super aur super key star koo maapati haye. supernostic elissa maanav super key khilaf monoclonal mouse aur choohe key antibody kaa upayog kartaa haye.
polyclonal antibody kaa upayog karane kii tulanaa mein monoclonal antibody kaa upayog karane key laabhon mein shamil hainh uchch ekroopata, gair-vishisht antibody kii anupasthiti aur koee batch-too-batch yaa lott-too-lott parivartansheelta naheen. isake parinamswarup ack bahut hii majboot aur vishvasaniya parakh hoti haye.
ack 'sandwich' thhos-charan antibody, super aur peroxidase-sanyugmit antibody seey banaa hotaa haye. rogi key namoone mein super kii sandrata (ng/ml plasma) koo saat super manakon seey taiyar calibration vakr key aadhar parr antarveshan key madhyam seey nirdhaarit kiya jaataa haye. swasth maanav rakt daataa namoonon key khilaf punarsanyojit super manakon koo calibrate kiya jaataa haye. avashoshan koo 650 nm sandarbh filter key saath 450 nm parr ack microtiter plate reader kaa upayog karke maapa jaataa haye. rakt key namoonon seey super star kaa maap mootra yaa mastishk reedh kii huddy key taral padaarth seey maap kii tulanaa mein adhik sateekta aur sateekta pradaan kartaa haye. jukam jaisi kshanik bimari seey super star naheen badalata haye. bhandaran key bavjood rakt kaa namuna lene key baad bhee yeh sthir rahata haye.
0. 1 aur 4.0 ng/ml key beach key supernostic maap seey pataa chalata haye kii ack rogi swasth haye, unaki pratiraksha pranali key liye koee chunauti naheen haye aur ack avasarvaadi sankraman yaa soojan key koee sanket yaa lakshan naheen hain; aabaadi key beach ausat star 3.4 ng/ml haye. haalaanki, ack rogi kii pratiraksha pranali koo 4.0 seey oopar aur 6.0 ng/ml taka key uchch star parr 'nakaratmak roop seey sakriya' maanaa jaa sakata haye, joe sambhaavit sankraman yaa uchch star kii soojan kaa sanket detaa haye. iss mamle mein, ack rogi kaa swaasthya bigadane kii sambhavana haye aur usey aage key pareekshan key liye bheja jaanaa chaahiye. 6. 0 ng/ml seey dohare ankon key star taka key supernostic maap ack gambhir bimari kaa sanket dey sakate hain joe teji seey ack gambhir sthiti mein badh rahee haye. gahan dekhbhal ikai mein rogiyon kaa ausat star 10 ng/ml haye. vibhinn jaatiyon key liye aantarik roop seey anukool staron mein koee antar naheen haye; haalaanki, purush aur mahila key liye paimana bhinn hotaa haye.
dou supernostic pareekshan upalabdh hain. supernostic maanak elissa (code nam. aeye. aeye. tii. 1) anusandhaan upayog aur badey parikshanon key liye haye, jisamen ack batch mein 41 namoone double mein hotey hain. supernostic flex elissa (code nam. aeye. aeye. tii. 2) koo 93 namoonon seey yukt naidaanik anuprayogon key liye vikasit kiya gayaa haye, joe modular aur lachila haye, aur 2 ghanton mein poori tarah seey matratmak parinam detaa haye.
vyaavhaarik vichaar.
supernostic kitt mein kaee varshon kaa prasheetit shelf jeevan hotaa haye aur jaba ise jamaaya jaataa haye, tou ise lambe samay taka rakhaa jaa sakata haye. kitt koo upayog karane seey pahale aadhe ghante key liye kamare key tapman parr baithana chaahiye lekin ise kamare key tapman parr teen seey chaar ghante taka rakhaa jaa sakata haye. supernostic flex elissa (code nam. a002) 2 ghante mein poori tarah seey matratmak parinam pradaan karane mein saksham haye. supernostic koo badey, batch pareekshan key roop mein chalaaya jaataa haye jisamen anusandhaan uddeshyon key liye double mein 41 namoone yaa ack samay mein naidaanik upayog key liye 93 namoone hotey hain.
haalaanki supernostic key paas vartamaan mein fda anumodan naheen haye, lekin yeh poore europe mein vitaran key liye see. ee./aaee. vee. dee. chihnit haye. super samanya swaasthya koo ingit karane key liye ack purvanumanatmak pareekshan haye, aur iska upayog kissy vishesh bimari kaa sujhaav dene key liye ack naidaanik upkaran key roop mein naheen kiya jaa sakata haye. mastishk tumour kaa pataa lagaane mein super kaa upayog naheen kiya jaa sakata haye kyonki super anu rakt mastishk baadha key madhyam seey sthanantarit naheen hoe sakata haye.

