fibrosis

fibrosis, jise fibrotic nishan key roop mein bhee jaanaa jaataa haye, ack rogjanak ghaav upchaar haye jisamen sanyoji ootak samanya perenkaimal ootak kii jagah iss hudd taka letaa haye kii yeh aniyantrit hoe jaataa haye, jisase kaafee ootak punarnirmaan aur sthaayi nishan ootak kaa nirmaan hotaa haye.
baar-baar chot lagana, purani soojan aur marammat fibrosis key liye atisamvedansheel hoti haye, jahaan collegen jaise extracellular matricks ghatakon kaa aakasmik atyadhik sanchay fibroblast dwara utpann hotaa haye, jisase ack sthaayi fibrotic nishan kaa nirmaan hotaa haye.
chot key jawab mein, ise nishan kahaa jaataa haye, aur yadi fibrosis ack ekal koshika rekha seey utpann hotaa haye, tou ise fibroma kahaa jaataa haye. shaaririk roop seey, fibrosis sanyoji ootak koo jamaa karane kaa kaary kartaa haye, joe antarnihit anga yaa ootak kii samanya sanrachana aur kaary mein hastakshep curr sakata haye yaa poori tarah seey roque sakata haye. fibrosis kaa upayog reshedar ootak key atirikt jamaav kii rogjanak sthiti kaa varnan karane key saath-saath upchaar mein sanyoji ootak key jamaav kii prakriya kaa varnan karane key liye kiya jaa sakata haye. baahya koshikiya matricks (ee. see. aim.) protein key rogjanak sanchay dwara paribhaashit, fibrosis key parinamswarup prabhaavit vyakti parr nishan aur motaa hoe jaataa haye, yeh saar mein ack atishayoktipurna ghaav upchaar pratikriya haye joe samanya anga kaary mein hastakshep karati haye.
shareer vigyaan.
fibrosis nishan kii prakriya key samaan haye, jisamen donon mein collegen aur glycosaminoglycane sahit sanyoji ootak koo neeche rakhane vaale uttejak fibroblast shamil hain. prakriya taba shuru hoti haye jaba macrophage jaisi pratiraksha koshikaaen ghulansheel karakon koo chhodati hain joe fibroblast koo uttejit karate hain. sabse achchi tarah seey visheshta vaalaa pro-fibrotic madhyasth tii. jee. aff. beeta haye, joe macrophage key saath-saath interstitium naamak satahon key beach kissy bhee kshatigrast ootak dwara jaari kiya jaataa haye. fibrosis key anya ghulansheel madhyasthon mein see. tii. jee. aff., platelet-vyutpann vriddhi kaarak (pee. dee. jee. aff.), aur interleukin 10 (aaee. ell.-10) shamil hain. yeye sanket pargaman maargon jaise kii act/aim. tii. aar. aur smaad maargon koo shuru karate hain joe antatah fibroblast key prasaar aur sakriyan kii or leey jaate hain, joe aspas key sanyoji ootak mein atirikt koshikiya matricks jamaa karate hain. ootak marammat kii yeh prakriya ack jatil prakriya haye, jisamen baahya koshikiya matricks (ee. see. aim.) sanshleshan aur ksharan key sakht viniyaman key saath samanya ootak vastukala kaa rakharkhaav sunishchit kiya jaataa haye. haalaanki, poori prakriya, halanki aavashyak haye, ack pragatisheel aparivartaniya fibrotic pratikriya kaa kaaran bunn sakati haye yadi ootak kii chot gambhir yaa doharaae jaane vaali haye, yaa yadi ghaav bharane kii pratikriya swayam viniyamit hoe jaati haye.
shaaririk sthiti.
fibrosis shareer key bheetar kaee ootakon mein hoe sakata haye, aamtaur parr soojan yaa kshati key parinamswarup, aur udaharanon mein shamil hainh
dill.
myocardial fibrosis key mukhya roop seey dou roop hotey hainh

