
wesley sundqvist

wesley aaee. sundqvist (janm 1959) ack americi jaiv rasaayanagya hain. sundqvist koo retrovirus, vishesh roop seey aich. aaee. vee. key koshikiya, aanvik aur sanrachanaatmak jeev vigyaan key adhyayan key liye jaanaa jaataa haye. vaha koshika vibhajan mein escurt maarg kaa adhyayan karane key liye bhee jaanaa jaataa haye.
wesley sundqvist kaa janm sent mein huaa thaa. paul, minnesota 1959 mein. way sent mein badey hue. paul minnesota aur washington, dee. see. unhone 1981 mein minnesota mein carlton college seey rasayan vigyaan mein snaatak kii degree praapt kii. carlton mein apane samay key dauran sundqvist ney forribalt pariyojana key samanvayak key roop mein kaary kiya, sigma xi key liye chune gaye aur unhein rashtriya yogyata chhatravritti (1977-81) praapt hui. sundqvist ney massachusets institute off technology mein stephen jey key saath phd poori kii. 1988 mein lippered. apani phd key baad, unhone surr aaron clug key tahat ingland key cambridge mein aanvik prayogshala mein postdoctoral shodh mein bhaag liya. 1992 mein sundqvist vishvavidyalaya key yuu. tii. aeye. key jaiv rasayan vibhaag mein shamil hoe gaye. sundqvist kaa vivaah nola sundqvist seey huaa haye, jisake saath vaha salt lake city, utaah mein rahata haye. unake dou vayask bachche hain, criss aur emily.
kaary aur khoj.
sundqvist vishisht professor hain aur yuu. tii. aeye. vishvavidyalaya mein jaiv rasayan vibhaag key adhyaksh hain, aur way ack shodh prayogshala kaa nirdeshan bhee karate hain. sundqvist prayogshala maanav pratiraksha kamee virus, aich. aaee. vee. parr dhyaan kendrit karate hue retrovirus key cellular, aanvik aur sanrachanaatmak jeev vigyaan parr kendrit haye. unaki prayogshala mein pramukh pariyojanaon mein shamil hain, 1) aavaran virus assembly 2) koshika vibhajan aur cancer mein escurt maarg kaary aur viniyaman, aur 3) hiv capsid sanrachana, pratikriti aur pratibandh.
virus assembly aur ubharana.
ack koshika chhodane aur sankraman failaane key liye, hiv viral kanon koo ack jhilli key bheetar aur koshika seey ankurit honah chaahiye. sundqvist ney paaya kii parivahan yaa escurt maarg key liye aavashyak mezban endosomal chhantaai maarg kaa upayog karke sankramit koshikaon seey hiv budd jaise retrovirus. aich. aaee. vee. escurt-madhyasthata vaale ubharane seey pahale jhilli key aavaran koo suvidhajanak banaane key liye angiomotin parivaar key mezban protein kaa bhee upayog kartaa haye. iss kshetra mein sundqvist kaa vartamaan shodh hiv kii assembly aur ubharane koo samajhane, isamen shamil mezban aur viral protein koo chihnit karane aur escurt maarg kaa upayog karane vaale virus key janmajaat pratiraksha pratibandh kaa pareekshan karane parr kendrit haye. sundqvist prayogshala ney nae proteins koo design aur visheshta dene key liye aachchhaadit virus assembly kii aavashyaktaon aur siddhanton kii apani samajh kaa bhee upayog kiya haye joe nanocages mein ikattha hoe sakate hain, koshikaon seey ankurit hoe sakate hain aur naee lakshit koshikaon mein maal leey jaa sakate hain.
escurt maarg kaary aur koshika vibhajan.
escurt maarg putikaon key gathan kii suvidha pradaan kartaa haye joe endosome mein ankurit hotey hain, neuronal chhantai, post-mitotic paramanu lifafe kaa punah sanyojan, antim charan koshika vibhajan (cytokinetic absition). cytokinetic absition dou dotter koshikaon key algaav koo puuraa kartaa haye, aur ack jaanch bindu koo samanvit karane mein bhee madad kartaa haye joe koshika vibhajan mein deree kartaa haye jaba taka kii mitotic prakriyaaen safaltapurvak poori naheen hoe jaati hain. kuchh cancer koshikaon mein, yeh viniyaman sahee dhang seey kaam naheen kartaa haye. sundqvist kii prayogshala inn prakriyaon kaa adhyayan vyaktigat escurt protein kii sanrachanaon aur karyon koo nirdhaarit karke curr rahee haye aur saha-karakon koo way absition aur absition checkpoint mein madhyasthata karane mein madad karane key liye bharti karate hain, aur sanket maarg joe unaki gatividhiyon koo niyantrit karate hain.
aich. aaee. vee. pratikriti aur pratibandh.
aich. aaee. vee. kaa capsid viral riverse transcription kii suvidha pradaan kartaa haye aur viral genome koo janmajaat pratiraksha pranali seey bachaata haye. sundqvist ney viral capsid kii fulreen shanku sanrachana koo paribhaashit kiya, jisase gilliod vigyaan mein atyadhik shaktishali aur lambe samay taka chalane vaale capsid avrodhakon key vikas key liye charan nirdhaarit karane mein madad milati haye. sundqvist prayogshala bhee koshika-mukt pranali mein hiv riverse transcription aur ekikaran kaa punargathan karane vaali pahali prayogshala thee. sundqvist aur unake sahyogiyon ney yeh paribhaashit karane mein bhee madad kii kii kaise mezban pratibandh kaarak, trim5alfa capsid key aspas pahachaantaa haye aur ikattha hotaa haye.
sammaan aur vaigyaanik viraasat.
1993 mein sundqvist koo searl scholars puraskar milaa.
2003 mein unhein roga kii samajh key liye jaiv rasayan aur aanvik jeev vigyaan key anuprayog key liye aeye. aiss. bee. aim. bee. aeye. aim. jee. aine. puraskar milaa.
2004 mein unhein rashtriya swaasthya sansthanon seey yogyata puraskar aur retroviorology key liye bernard fields puraskar donon praapt hue.
2017 mein unhein utkrishtata key liye vishvavidyalaya kaa yoota rosenblatt puraskar milaa.
unhein american academy off arts aind sciences (2011) aur national academy off sciences key liye chunaa gayaa haye. (2014).

