
aiss. aff. aich. key. 2

sphingosine kinnez 2 ack protein haye jise manushyon mein sphake 2 jeane dwara kootbaddh kiya jaataa haye.
yeh jeane dou sphingosine kinnez isozymes mein seey ack koo kootbaddh kartaa haye joe sphingosine key phosphorylation koo sphingosine 1-phosphat mein utprerit kartaa haye. sphingosine 1-phosphat pravaas, prasaar aur apoptosis sahit kaee koshikiya prakriyaon mein madhyasthata kartaa haye, aur angiogenesis aur tumergenesis koo badhaava dekar kaee prakaar key cancer mein bhee bhoomika nibhaata haye. encoded protein stun cancer key prasaar aur chemoragistance mein bhoomika nibha sakata haye. iss jeane key liye vaikalpik roop seey kaee isophorm koo encoding karane vaale spliesed transcript roop dekhe gaye hain. [refsec, agast 2011 dwara pradaan kiya gayaa]. 
shodhkartaon ney yeh bhee paaya kii copd jaise lakshnon vaale cs-exposed choohon key fefadon mein sphingosine kinnez 2 (sfhk2) kii abhivyakti aur sphingosine-1-phosphat (aiss1pee) kaa sraav kaafee hudd taka viniyamit thaa.