
amoberbital

amibarbital (jise pahale amylobarbitone yaa sodium ametal key roop mein ghulansheel sodium namak key roop mein jaanaa jaataa thaa) ack aisee dawa haye joe ack barbiturate vyutpann haye. isamen shaamak-sammohan guna hotey hain. yeh ack safed kristaliya pouder haye jisamen koee gandh naheen haye aur swaad thodaa kadwa haye. ise pahali baar 1923 mein germany mein sanshleshit kiya gayaa thaa. ise ack laghu seey madhyavarti abhinay barbiturate maanaa jaataa haye. yadi amibarbital koo vistaarit avadhi key liye liya jaataa haye, tou shaaririk aur manovaigyaanik nirbharta vikasit hoe sakati haye. amobarbital nikasi pralaap compan kii nakal karati haye aur jeevan key liye khatra hoe sakati haye. amibarbital kaa nirmaan ellie lilly aur company dwara america mein brand naam ametal key tahat chamkile neele goli key aakar key capsule (jise pulviewl key roop mein jaanaa jaataa haye) yaa gulabi goliyon (jise disk key roop mein jaanaa jaataa haye) mein kiya gayaa thaa jisamen 50,100, yaa 200 milligram dawa hoti thee. dawa kaa utpaadan bhee samanya roop seey kiya gayaa thaa. sadak parr "neele akash" key roop mein jaanaa jaane vaalaa amoberbital kaa vyaapak roop seey durupyog kiya gayaa thaa. amital, saath hii tunal, ack sanyojan dawa jisamen samaan matra mein secobarbital aur amobarbital hotey hain, donon kaa nirmaan 1990 key dashak key anta taka ellie lilly dwara kiya gayaa thaa. haalaanki, jaise-jaise benzodiazepine kii lokpriyata badhee, 1980 key dashak key madhya seey anta taka inn davaaon key liye prescription teji seey durlabh hoe gaye.
pharmacology.
choohe key thalamic slies mein ack "inn vitro" adhyayan mein, amobarbital ney gaaba receptors koo sakriya karke kaam kiya, jisase input pratirodh, avasaadgrast visfot aur tonic firing mein kamee aaee, vishesh roop seey ventrobasal aur intralaminer neurons mein, jabaki ack hii samay mein vyaktigat chloride chainalon parr visfot kii avadhi aur ausat chaalakta mein vriddhi hui; isase postsyneptic dhaaraon key ayam aur kshay donon samay mein vriddhi hui.
raperfusion key baad mitochondrial kaary koo sanrakshit karane key prayaas mein choohe key hriday mein mitochondrial electron parivahan koo rokane key liye ack adhyayan mein amibarbital kaa upayog kiya gayaa haye.
1988 key ack adhyayan mein paaya gayaa kii amibarbital secobarbital aur pentobarbital (avrohi crum mein) kii tulanaa mein cumm shakti key saath benzodiazepine receptor binding "inn vivo" koo badhaata haye, lekin phenobarbital aur barbital (avrohi crum mein) seey adhik hotaa haye. (secobarbital> pentobarbital> "amobarbital"> phenobarbital> barbital)
isamen 212 milligram/kigra aiss key choohon mein hotaa haye.see. 
chayapachaya.
amobarbital 3 '-hydroxymbarbital banaane key liye hydroxylation seey gujarta haye, aur 1-(beeta-dee-glucopyranosyl)-amobarbital banaane key liye aine-glucosidation.
sanket.
apramaanit/off-label.
jaba ack antahshira maarg dwara dheere-dheere diyaa jaataa haye, tou sodium amoberbital ack tathaakathit satya seeram key roop mein kaary karane key liye ack pratishtha rakhta haye. prabhaav key tahat, ack vyakti aisee jaankaari kaa khulasa karega kii samanya paristhitiyon mein way avaruddh curr denge. yeh sabse adhik sambhavana avrodh key nuksan key kaaran thee. iss tarah, iss dawa koo pahali baar wisconsin vishvavidyalaya mein villium blackwen dwara manorog rogiyon mein baadhaon koo darkinar karane key liye chikitsakiya roop seey niyojit kiya gayaa thaa. satya seeram key roop mein amobarbital kaa upayog iss khoj key kaaran vishvasaniyata khou chuka haye kii ack vishay koo ghatana kii "jhoothi smriti" rakhane key liye majboor kiya jaa sakata haye.
catatonic utparivartan key rogiyon kaa sakshatkar karane key liye dawa kaa upayog antahshira roop seey kiya jaa sakata haye, kabhi-kabhi neend koo rokane key liye caffein key saath jodaa jaataa haye.
iska upayog dwiteeya vishva yuddh key dauran sanyukt raajya america key sashastr balon dwara shale shock kaa ilaaj karane aur sainikon koo agrim pankti key kartavyon mein vaapas laane key prayaas mein kiya gayaa thaa. isake baad seey iss upayog koo bund curr diyaa gayaa haye kyonki shaktishali shaamak, sangyanatmak haani, aur dawa dwara prerit samanvaya seey sainikon kii kshetra mein upayogita bahut cumm hoe gaee haye. amoberbital kaa nirmaan ack baar america mein ellie lilly pharmaceuticals dwara capsule key roop mein brand naam amital key tahat kiya gayaa thaa. ise 80 key dashak kii shuruat mein bund curr diyaa gayaa thaa, jise kaafee hudd taka benzodiazepine parivaar kii davaaon dwara pratisthaapit kiya gayaa thaa. amobarbital kaa bhee vyaapak roop seey durupyog kiya gayaa thaa, jise unake neele capsule key kaaran sadakon parr "neele aasmaan" key roop mein jaanaa jaataa thaa.
virodhabhas.
amoberbital lete samay nimnalikhit davaaon seey bachana chaahieh
antahkriyaaen.
amoberbital harmonal janm niyantran key prabhaavon koo cumm karane key liye jaanaa jaataa haye.
overdose.
adhik matra key kuchh dushprabhavon mein bhram (gambhir); prativart mein kamee yaa haani; unindapan (gambhir); bukhaar; chidchidaapan (jaari); shareer kaa cumm tapman; kharaab nirnay; saans kii takleef yaa dheemi yaa pareshan saans lena; dheemi dill kii dhadkan; mund bhaashan; chaunka dene vaali; soney mein pareshani; aankho kii asamanya harkatein; kamjori (gambhir) shamil hain. gambhir overdose key parinamswarup binaa hastakshep key mrityu hoe sakati haye.
rasayan vigyaan.
sabhi barbiturates kii tarah, amobarbital (5-ethyl-5-isomyelbarbituric acid) koo euria vyutpannon key saath malonic acid vyutpannon kii pratikriya karke sanshleshit kiya jaataa haye. vishesh roop seey, amibarbital banaane key liye, α-ethyl-α-isoemalmonic ester koo euria (sodium athoxide kii upasthiti mein) key saath pratikriya kii jaati haye.
samaaj aur sanskriti.
iska upayog andress inglish-hord jaise kathit hatyaron koo doshi thaharaane key liye kiya gayaa haye, jinhone apani premika kii galaa ghontkar hatyaa curr dee thee, lekin nirdosh honey kaa daavaa kiya thaa. usey apane vakeel dwara gupt roop seey dawa dee gaee thee, aur isake prabhaav mein usane khulasa kiya kii usane uska galaa kyon ghonta aur kinn paristhitiyon mein.
28 agast, 1951 kii raat koo abhineta robbert walker key ghar key rakhwale ney unhein bhaavnaatmak sthiti mein paaya. usane walker key manochikitsak koo bulaaya joe aaya aur behosh karane key liye amobarbital kaa ilaaj karaaya. walker kathit taur parr apane bhaavnaatmak prakop seey pahale sharaab pee rhaa thaa, aur aisaa maanaa jaataa haye kii amobarbital aur sharaab key sanyojan key parinamswarup gambhir pratikriya hui. natijatan, vaha baahar nickle gayaa aur usane saans lena bund curr diyaa, aur usey punarjeevit karane key sabhi prayaas whiffle hoe gaye. walker kii 32 saal kii umr mein mrityu hoe gaee. 
british abhineta aur haasya kalakar tonny hancock ney 1968 mein sharaab key saath dawa kaa upayog karke australia mein khud koo maar daala.
ellie lilly ney brand naam amital key tahat amobarbital kaa nirmaan kiya, ise 1980 key dashak mein bund curr diyaa gayaa thaa, jise badey paimaane parr benzodiazepine parivaar kii davaaon dwara pratisthaapit kiya gayaa thaa. amyatal kaa bhee vyaapak roop seey durupyog kiya gayaa thaa. amoberbital key liye sadak key naamon mein unake neele capsule key kaaran "blues", "blue angels", "blue birds", "blue devils" aur "blue havens" shamil hain.
saanskritik sandarbh.
laine dieton key 1967 key upanyaas "aeye monghi place too dye" mein, ameetal aur lsd key sanyojan kaa upayog anaam naayak koo usaki gatividhiyon key baare mein poochtaachh kaa jawab dene key liye kiya jaataa haye.
thomas pinchon key 1973 key upanyaas "gravities rainbow" mein, sodium amital kaa upayog ack sainya khufiya ikai dwara 1930 key dashak key dauran massachusets (adhyaay 1) key apane grih raajya mein african-amerikiyon key khilaf safed amerikiyon key naslavaad parr tyrone slothrope (upanyaas key naayak) key vichaaron koo nikaalane key liye kissy prakaar key satya seeram key roop mein kiya jaataa haye.
1994 kii haasya action thriller satya jhooth mein, naayak hairi taskar (arnold schwarzenegger dwara chitrit) koo aatankvaadiyon dwara poochtaachh kiye jaane parr satya seeram key roop mein sodium amital diyaa jaataa haye.
2001 mein, ack chikitsak (sherley night), "episode" daman (), usake rogi kaa "sodium amital" key saath ilaaj kartaa haye. charitra dow. (bee. dee. wong) kaa daavaa haye kii dawa ack rogi koo sujhaav key liye itna samvedansheel chhod detee haye, kii chikitsak rogi mein jhoothi yaaden pratyaaropit karane mein saksham hotaa haye.
2003 mein, animated shrinkhala sealab 2021 season 3, episode 7, "tourist season", dow. quentin kyu. quin, jise brett butler ney aavaaj dee haye, paryatakon key ack samooh mein smritibhransh koo prerit karane key liye "sodium amital" kaa upayog kartaa haye, taaki unhein cap dwara khargosh-mastishk yojana key parinamswarup sealub key khilaf kaarravaai karane seey rokaa jaa sakey. marfi. vaha paryatakon key jaane seey pahale ack muft maadak peya mein ack upahaar key roop mein khuraak detaa haye, aur matra mein vaha varnan kartaa haye kii "ack haathi koo bhool sakata haye. 
2005 kii film mein, mukhya virodhi "sodium amital" kaa upayog una logon koo gupt roop seey sangyaaharan karane key liye kartaa haye joe unake anusaar unake bete kii mrityu key liye jimmedaar they, aur unamen atyadhik matibhram paida karate hain.
2022 mein, danne braun key "khoye hue prateek" key episode 06 mein, "diophantine chhadm naam" mein, sodium amital kaa upayog siyaa dwara ack satya seeram key roop mein kiya jaataa haye.

