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Like so many things it depends who you ask. For some it refers to the entire workflow from the moment a need is identified through to the final payment and warranty administration for a service or item. Others describe it as online sourcing and purchasing of items from a catalogue. Wikipedia says: “E-procurement (electronic procurement, sometimes also known as supplier exchange) is the business-to-business or business-to-consumer or business-to-government purchase and sale of supplies, work, and services through the Internet as well as other information and networking systems, such as electronic data interchange and enterprise resource planning.
In this Blog the term e-Procurement is used to describe the workflows that relate to the external (Vendor and Contractor) facing processes required to purchase goods, services or construction over the internet.
In this very simplified description of the procurement process, the externally facing activities (elements 4, 5, 6) and the interface (element 3 and 7) between those and the internally facing activities are the areas that our software and services streamline.
As we draw near the end of 2011, there are many predictions around the IT industry trend for 2012. The recently published "Nucleus Research Top Ten Predictions 2012" places emphasis on the rise of cloud computing (prediction #2). According to the article, cloud computing was proven to be nearly five times more productive than the traditional development in 2011. Furthermore, the article also states, “When companies do have money to spend, their two main choices are technology and people. A recent Nucleus survey found technology is winning hands down, with 50 percent of US companies planning to increase their technology spend in 2012 [Nucleus Research l106, Nucleus 2012 IT spending survey, September 2011].” Thus, many firms will look into increasing their productivity via technology adoption next year.
So the trend is clear. Businesses are moving towards cloud computing to take advantage of its many benefits including increased productivity, cost savings, accountability and sustainability. In today’s construction industry, online document control, online planroom, and online bidding are examples of cloud computing technologies that are increasingly adopted.
A few years ago most bidders would not have pictured themselves submitting their construction bids online in a paperless environment. It represents a major change from decades of travelling to closings, faxing bid amendments, last minute decisions and all the drama that comes with it. Today, this green construction technology has finally arrived. Online bid submission has the double benefit of being a sustainable process along with the benefits of substantially improved efficiency. Supported with a complete document management system and audit trail, it ensures a complete record of who saw what documents and when. This combination greatly reduces the risk of costly bid related errors or omissions.
A great example of an early adopter of this technology is the city of Prince George in British Columbia, Canada. It leads the way in the electronic tendering of capital projects closing many of the projects that have utilized the recently introduced Owner Bid Management and Bid Submission applications within BidCentral. BidCentral is powered by PlanSource and is a suite of services that was designed specifically for the construction industry and is modeled after the processes that have long been accepted as industry standards. The City of Prince George procurement team and the bidders involved in the bidding process gave BidCentral very positive reviews and recognized it as the new construction procurement standard (view video).
Our company has been delivering Software as a Service (SaaS) since we were founded in 2000. At that time what we did was generally described as Application Service Provider (ASP). The latest iteration incorporates the more ethereal sounding ‘cloud computing’ reference. Whatever term you use the functionality consists of accessing software via the Internet rather than from your local computer or server. So, is this an effective way to acquire and use software applications?
Faster and less expensive implementation makes the new systems more digestible.
As a company that has been significantly ahead of the wave on this method of delivering useful functionality to the construction industry for many years we can easily agree with Mr. Fornes statements. We already deliver powerful solutions for the estimating community and are experiencing significant interest in some of the latest functionality we deliver online including planrooms, document control, onscreen takeoff, online bid submission and submittal management. The industry trend is definitely moving towards increased use of SaaS.

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like so many things it depends who you ask. for some it refers to the entire workflow from the moment a need is identified through to the final payment and warranty administration for a service or item. others describe it as online sourcing and purchasing of items from a catalogue. wikipedia says: “e-procurement (electronic procurement, sometimes also known as supplier exchange) is the business-to-business or business-to-consumer or business-to-government purchase and sale of supplies, work, and services through the internet as well as other information and networking systems, such as electronic data interchange and enterprise resource planning.
in this blog the term e-procurement is used to describe the workflows that relate to the external (vendor and contractor) facing processes required to purchase goods, services or construction over the internet.
in this very simplified description of the procurement process, the externally facing activities (elements 4, 5, 6) and the interface (element 3 and 7) between those and the internally facing activities are the areas that our software and services streamline.
as we draw near the end of 2011, there are many predictions around the it industry trend for 2012. the recently published "nucleus research top ten predictions 2012" places emphasis on the rise of cloud computing (prediction #2). according to the article, cloud computing was proven to be nearly five times more productive than the traditional development in 2011. furthermore, the article also states, “when companies do have money to spend, their two main choices are technology and people. a recent nucleus survey found technology is winning hands down, with 50 percent of us companies planning to increase their technology spend in 2012 [nucleus research l106, nucleus 2012 it spending survey, september 2011].” thus, many firms will look into increasing their productivity via technology adoption next year.
so the trend is clear. businesses are moving towards cloud computing to take advantage of its many benefits including increased productivity, cost savings, accountability and sustainability. in today’s construction industry, online document control, online planroom, and online bidding are examples of cloud computing technologies that are increasingly adopted.
a few years ago most bidders would not have pictured themselves submitting their construction bids online in a paperless environment. it represents a major change from decades of travelling to closings, faxing bid amendments, last minute decisions and all the drama that comes with it. today, this green construction technology has finally arrived. online bid submission has the double benefit of being a sustainable process along with the benefits of substantially improved efficiency. supported with a complete document management system and audit trail, it ensures a complete record of who saw what documents and when. this combination greatly reduces the risk of costly bid related errors or omissions.
a great example of an early adopter of this technology is the city of prince george in british columbia, canada. it leads the way in the electronic tendering of capital projects closing many of the projects that have utilized the recently introduced owner bid management and bid submission applications within bidcentral. bidcentral is powered by plansource and is a suite of services that was designed specifically for the construction industry and is modeled after the processes that have long been accepted as industry standards. the city of prince george procurement team and the bidders involved in the bidding process gave bidcentral very positive reviews and recognized it as the new construction procurement standard (view video).
our company has been delivering software as a service (saas) since we were founded in 2000. at that time what we did was generally described as application service provider (asp). the latest iteration incorporates the more ethereal sounding ‘cloud computing’ reference. whatever term you use the functionality consists of accessing software via the internet rather than from your local computer or server. so, is this an effective way to acquire and use software applications?
faster and less expensive implementation makes the new systems more digestible.
as a company that has been significantly ahead of the wave on this method of delivering useful functionality to the construction industry for many years we can easily agree with mr. fornes statements. we already deliver powerful solutions for the estimating community and are experiencing significant interest in some of the latest functionality we deliver online including planrooms, document control, onscreen takeoff, online bid submission and submittal management. the industry trend is definitely moving towards increased use of saas.


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Veterans Day is a federal holiday, but this year, many banks and credit unions will be open for business. Created to honor men and women who have served in the United States Armed Forces, the holiday is observed annually on November 11. However, because the 11th falls on a Saturday in 2017, most government offices and schools will be closed on Friday, November 10.
What does that mean for banks? Will they be closed both Friday and Saturday? Here’s the latest scoop on Veterans Day banking hours. Keep in mind, if your bank is closed, most major banks have mobile apps that allow you to check your balance, pay bills, and transfer funds. And if you need cash, make sure you use an ATM that is associated with your bank so you don’t have to pay a hefty fee to withdraw some holiday weekend cash.
The Federal Reserve Bank will be closed on Veterans Day, but some banks have opted to stay open on Friday and/or Saturday. While some financial institutions may open for limited holiday hours, others, including TD Bank, will be open regular business hours on Friday and Saturday.
According to the Holiday Schedule, in addition to TD Bank, many other major banks will also stay open during regular business hours on Friday, including Bank of America, Citibank, Chase, Capital One, Citizens, HBSC, PNC, Santander, SunTrust, US Bank, and Wells Fargo.
On Saturday, it’s going to be hit or miss with bank hours. Many banks are open limited hours on weekends, but most will be closed to observe the Veterans Day holiday on Saturday, November 11. Branch offices for some banks located in retail stores and supermarkets may be open, but it’s important to call ahead to confirm hours at the branch office near you.
To add to the confusion about what’s open and what’s closed, federal offices — including the IRS, Social Security, federal courthouses, the DMV/RMV, and local social services and food stamp offices — will be closed on Friday, November 10 in observance of the Veterans Day holiday. However, the U.S. Postal Service will be open on Friday and closed on Saturday.
Although banks and government offices will be closed on either Friday or Saturday, rest assured that retail stores and restaurants will be open throughout the three-day weekend. According to a previous report by the Inquisitr, numerous restaurants will be offering free meals for veterans and active duty military this weekend to honor the brave men and women who have served, or are currently serving, in the U.S. Armed Forces.

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veterans day is a federal holiday, but this year, many banks and credit unions will be open for business. created to honor men and women who have served in the united states armed forces, the holiday is observed annually on november 11. however, because the 11th falls on a saturday in 2017, most government offices and schools will be closed on friday, november 10.
what does that mean for banks? will they be closed both friday and saturday? here’s the latest scoop on veterans day banking hours. keep in mind, if your bank is closed, most major banks have mobile apps that allow you to check your balance, pay bills, and transfer funds. and if you need cash, make sure you use an atm that is associated with your bank so you don’t have to pay a hefty fee to withdraw some holiday weekend cash.
the federal reserve bank will be closed on veterans day, but some banks have opted to stay open on friday and/or saturday. while some financial institutions may open for limited holiday hours, others, including td bank, will be open regular business hours on friday and saturday.
according to the holiday schedule, in addition to td bank, many other major banks will also stay open during regular business hours on friday, including bank of america, citibank, chase, capital one, citizens, hbsc, pnc, santander, suntrust, us bank, and wells fargo.
on saturday, it’s going to be hit or miss with bank hours. many banks are open limited hours on weekends, but most will be closed to observe the veterans day holiday on saturday, november 11. branch offices for some banks located in retail stores and supermarkets may be open, but it’s important to call ahead to confirm hours at the branch office near you.
to add to the confusion about what’s open and what’s closed, federal offices — including the irs, social security, federal courthouses, the dmv/rmv, and local social services and food stamp offices — will be closed on friday, november 10 in observance of the veterans day holiday. however, the u.s. postal service will be open on friday and closed on saturday.
although banks and government offices will be closed on either friday or saturday, rest assured that retail stores and restaurants will be open throughout the three-day weekend. according to a previous report by the inquisitr, numerous restaurants will be offering free meals for veterans and active duty military this weekend to honor the brave men and women who have served, or are currently serving, in the u.s. armed forces.


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Markets in 2014, especially stock markets, have done well.
While it hasn’t been all smooth sailing, as we saw in October, 2014 saw the emergence of growth in the US drove stocks higher and saw a generalised bid tone in risk assets around the world.
2015 is going to be very different according to TD Securities in its 2015 Global Outlook – Rates, FX and Commodities Research released overnight.
That means that traders are faced with a “more uncertain macro and market environment and suggests limited scope for rates to rise globally.” It also means that TD has delayed its rate hike expectations for the G10 other than the Fed and Bank of Canada.

lowercased:
markets in 2014, especially stock markets, have done well.
while it hasn’t been all smooth sailing, as we saw in october, 2014 saw the emergence of growth in the us drove stocks higher and saw a generalised bid tone in risk assets around the world.
2015 is going to be very different according to td securities in its 2015 global outlook – rates, fx and commodities research released overnight.
that means that traders are faced with a “more uncertain macro and market environment and suggests limited scope for rates to rise globally.” it also means that td has delayed its rate hike expectations for the g10 other than the fed and bank of canada.


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JAKARTA ~ Indonesia and Pakistan have agreed to work together to stamp out radical Islam as part of efforts to stop future deadly militant attacks, state media said.
They have formed a joint working group amid concerns some Indonesians have attended Islamic schools in Pakistan and have later undergone training in extremist camps, said Indonesian senior anti-terror officer Ansyaad Mbai.
“We will work together in a joint working group to find, among others, a new method to eradicate radicalism in Islam that often becomes the root of terrorism,” Mbai was quoted as saying by the Antara news agency.
He did not say whether Pakistani officials had visited the Southeast Asian nation recently to formalize the agreement, nor who would make up the group.
Mbai said Indonesia had formed similar working groups with Saudi Arabia and Turkey.

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jakarta ~ indonesia and pakistan have agreed to work together to stamp out radical islam as part of efforts to stop future deadly militant attacks, state media said.
they have formed a joint working group amid concerns some indonesians have attended islamic schools in pakistan and have later undergone training in extremist camps, said indonesian senior anti-terror officer ansyaad mbai.
“we will work together in a joint working group to find, among others, a new method to eradicate radicalism in islam that often becomes the root of terrorism,” mbai was quoted as saying by the antara news agency.
he did not say whether pakistani officials had visited the southeast asian nation recently to formalize the agreement, nor who would make up the group.
mbai said indonesia had formed similar working groups with saudi arabia and turkey.


text: Maureen Jackson knew life as a trainee nurse wouldn't be easy, but she didn't expect her hospital to be badly bombed on her first shift. Plus Maureen still has her family and friends in Mulberry Lane to keep her busy – she's needed as much there as she is by her patients. Running the pub on the corner of Mulberry Lane, Peggy Ashley is used to taking in all sorts of waifs and strays. But the arrival of a dashing American captain has got tongues wagging about Mulberry Lane's favourite landlady... Janet Ashley's husband is back from the frontline. Which is more than so many of the wives of Mulberry Lane. But her beloved Mike is a completely different man from the one she fell in love with – and what's more he doesn't remember her, or their young daughter. How do you cope when your darling husband is a virtual stranger? As WW2 continues around them, the women of Mulberry Lane know that community spirit and friendship is the key to surviving the Blitz.

lowercased: maureen jackson knew life as a trainee nurse wouldn't be easy, but she didn't expect her hospital to be badly bombed on her first shift. plus maureen still has her family and friends in mulberry lane to keep her busy – she's needed as much there as she is by her patients. running the pub on the corner of mulberry lane, peggy ashley is used to taking in all sorts of waifs and strays. but the arrival of a dashing american captain has got tongues wagging about mulberry lane's favourite landlady... janet ashley's husband is back from the frontline. which is more than so many of the wives of mulberry lane. but her beloved mike is a completely different man from the one she fell in love with – and what's more he doesn't remember her, or their young daughter. how do you cope when your darling husband is a virtual stranger? as ww2 continues around them, the women of mulberry lane know that community spirit and friendship is the key to surviving the blitz.


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This is a placeholder page for William Luther, which means this person is not currently on this site. We do suggest using the tools below to find William Luther.
You are visiting the placeholder page for William Luther. This page is here because someone used our placeholder utility to look for William Luther. We created this page automatically in hopes William Luther would find it. If you are not William Luther, but are an alumni of South Hagerstown High School, register on this site for free now.

lowercased:
this is a placeholder page for william luther, which means this person is not currently on this site. we do suggest using the tools below to find william luther.
you are visiting the placeholder page for william luther. this page is here because someone used our placeholder utility to look for william luther. we created this page automatically in hopes william luther would find it. if you are not william luther, but are an alumni of south hagerstown high school, register on this site for free now.


text:
Yes – You Can Prosper In These Difficult Times.
Whenever I ask, “What would you like me to do a presentation on” I always get, “Teach us how to get more clients!” Or, “Show us how to earn a higher & more consistent Income.” Or this one, “We want a presentation on how to have an income even when we are not seeing clients.” Well, that is what this program is all about, and much more. Read on and you will see what I mean.
Build Your Business Seminar – This package contains a two hour recording (on 2 CDs) of a presentation given to a group of hypnosis professionals who invited Cal Banyan to teach them how to build their hypnosis practices.
Handouts On Disk – there is another CD with all of the handouts from the course so you get it all.
SPECIAL BONUS CDs – After the talk, Cal Banyan went back into his office, sat down and then piled on a whole bunch of great ways to promote your practice, make more money. This package is worth much more than its weight in gold. Using just one of these techniques can earn you thousands, and he piles on over 60 practice promoting, money making techniques!
This Is A “Gold Mine”!
These 4 Hours of Information That Will Transform Your Hypnosis Practice. Learn more about this new hypnosis training program that will give you the tools you need to take your hypnosis practice to the next level, and the next, and the next…Click this link, Turn Your Hypnosis Practice Into A “Gold Mine” Professional Practice Building Program. And save a bundle this week only as part of our introductory offer.
Why am I making such a great offer? We want your testimonials. After you take advantage of this great discount on this new hypnosis practice training program; we just ask that, after you go through this program, that you write us a note to let us know how you liked it (of course we won’t hold you to doing that).
Regular price is $69.95, but for this week only, you get to own this “Gold Mine” of hypnosis practice building techniques for only $34.97. That is HALF OFF this week only!
Learn more or order now. Downloadable Version Available (so you can have the program now with no shipping and no delay).

lowercased:
yes – you can prosper in these difficult times.
whenever i ask, “what would you like me to do a presentation on” i always get, “teach us how to get more clients!” or, “show us how to earn a higher & more consistent income.” or this one, “we want a presentation on how to have an income even when we are not seeing clients.” well, that is what this program is all about, and much more. read on and you will see what i mean.
build your business seminar – this package contains a two hour recording (on 2 cds) of a presentation given to a group of hypnosis professionals who invited cal banyan to teach them how to build their hypnosis practices.
handouts on disk – there is another cd with all of the handouts from the course so you get it all.
special bonus cds – after the talk, cal banyan went back into his office, sat down and then piled on a whole bunch of great ways to promote your practice, make more money. this package is worth much more than its weight in gold. using just one of these techniques can earn you thousands, and he piles on over 60 practice promoting, money making techniques!
this is a “gold mine”!
these 4 hours of information that will transform your hypnosis practice. learn more about this new hypnosis training program that will give you the tools you need to take your hypnosis practice to the next level, and the next, and the next…click this link, turn your hypnosis practice into a “gold mine” professional practice building program. and save a bundle this week only as part of our introductory offer.
why am i making such a great offer? we want your testimonials. after you take advantage of this great discount on this new hypnosis practice training program; we just ask that, after you go through this program, that you write us a note to let us know how you liked it (of course we won’t hold you to doing that).
regular price is $69.95, but for this week only, you get to own this “gold mine” of hypnosis practice building techniques for only $34.97. that is half off this week only!
learn more or order now. downloadable version available (so you can have the program now with no shipping and no delay).


text:
Forcepoint is seeking a full-time professional services engineer to facilitate installation, configuration, integration, management and training of Forcepoint’s comprehensive suite cyber products. This individual must be highly motivated, have great interpersonal skills, and be a quick learner. The successful candidate will be offered specialized training to support our technologies and is expected to become proficient in all aspects of complex software solution deployment. Remote work location will be considered. This position will require up to 75% domestic and international travel. To be considered, you must be willing to travel and reside within close proximity of a major airport.
Provide training, troubleshooting, and on-site support to customers including version upgrades.
4+ years with demonstrated experience in cyber security to include practices/methodologies, associated technologies, application design and development and/or experience in an operational environment.

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forcepoint is seeking a full-time professional services engineer to facilitate installation, configuration, integration, management and training of forcepoint’s comprehensive suite cyber products. this individual must be highly motivated, have great interpersonal skills, and be a quick learner. the successful candidate will be offered specialized training to support our technologies and is expected to become proficient in all aspects of complex software solution deployment. remote work location will be considered. this position will require up to 75% domestic and international travel. to be considered, you must be willing to travel and reside within close proximity of a major airport.
provide training, troubleshooting, and on-site support to customers including version upgrades.
4+ years with demonstrated experience in cyber security to include practices/methodologies, associated technologies, application design and development and/or experience in an operational environment.


text:
Now that we’re into our second week of rotational grazing, I’ve take the time to get the Gator, my “grazing-mobile,” prepped for the season.
We rotate animals to new paddocks every 3-4 days. I like to have my go-to-supplies on hand so I’m not constantly running back to the barn or the shop for things, and then back again.
This season I also spray painted some of the harder to find in the grass items blaze orange in the event I misplace something. I should be ready for just about anything when it comes to fence repair, waterline repair and working with my goats and guardian dogs.

lowercased:
now that we’re into our second week of rotational grazing, i’ve take the time to get the gator, my “grazing-mobile,” prepped for the season.
we rotate animals to new paddocks every 3-4 days. i like to have my go-to-supplies on hand so i’m not constantly running back to the barn or the shop for things, and then back again.
this season i also spray painted some of the harder to find in the grass items blaze orange in the event i misplace something. i should be ready for just about anything when it comes to fence repair, waterline repair and working with my goats and guardian dogs.


text:
Trench Coat Pattern Extraordinary Simplicity Pattern 48 Trench Coat Matrix Costume Misses Sizes 48 was posted in September 28 2018 at 4:36 am and has been seen by 9 users. Trench Coat Pattern Extraordinary Simplicity Pattern 48 Trench Coat Matrix Costume Misses Sizes 48 is best picture that can use for individual and noncommercial purpose because All trademarks referenced here in are the properties of their respective owners. If you want to see other picture of Trench Coat Pattern Extraordinary Simplicity Pattern 48 Trench Coat Matrix Costume Misses Sizes 48 you can browse our other pages and if you want to view image in full size just click image on gallery below.
V48 Misses’ DoubleBreasted Trench Coats and Belt Sewing Pattern Named Clothing ISLA TRENCH COAT Downloadable Pattern Trench Coat Sewing Pattern 48 Madetomeasure sewing pattern Simplicity 48 Threads Lined Coat Sew It Yourself Lace Trench Coat Lucky Lucille Robson Coat Sewaholic Patterns Instructions for drafting men’s trench coat Sewing Pinterest McCall’s Sewing Pattern M48 Collared and Seamed Coats Digital Isla Trench Coat Sewing Pattern Shop Oliver S V48 Misses’ DoubleBreasted Trench Coats and Belt Sewing Pattern Trench Coat Pattern.

lowercased:
trench coat pattern extraordinary simplicity pattern 48 trench coat matrix costume misses sizes 48 was posted in september 28 2018 at 4:36 am and has been seen by 9 users. trench coat pattern extraordinary simplicity pattern 48 trench coat matrix costume misses sizes 48 is best picture that can use for individual and noncommercial purpose because all trademarks referenced here in are the properties of their respective owners. if you want to see other picture of trench coat pattern extraordinary simplicity pattern 48 trench coat matrix costume misses sizes 48 you can browse our other pages and if you want to view image in full size just click image on gallery below.
v48 misses’ doublebreasted trench coats and belt sewing pattern named clothing isla trench coat downloadable pattern trench coat sewing pattern 48 madetomeasure sewing pattern simplicity 48 threads lined coat sew it yourself lace trench coat lucky lucille robson coat sewaholic patterns instructions for drafting men’s trench coat sewing pinterest mccall’s sewing pattern m48 collared and seamed coats digital isla trench coat sewing pattern shop oliver s v48 misses’ doublebreasted trench coats and belt sewing pattern trench coat pattern.


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Anderson’s disease is also known as chylomicron retention disease which is a rare hereditary disease. It is an autosomal recessive disease characterized by low plasma lipid and low lipid-soluble vitamins (such as vitamin E and vitamin D). After the digestion of food, lipids, and lipid soluble vitamins are absorbed in the human body with the help of chylomicrons. A lack of chylomicron can interrupt the transport of molecules from intestine to the bloodstream resulting in malabsorption. Subjects with these disorders show different clinical manifestations which were initially described by Anderson and colleagues, hence it was called as “Anderson’s disease”. Genotyping has revealed that Anderson's and chylomicron retention disease are in fact the same disease.
Anderson' disease and chylomicron retention disease is the same disease which has been proved genotypically. The disease is caused by the mutation in the gene SAR1B (formerly SARA2), which encodes the SAR1B protein. Mutation results in the defect in chylomicron secretion, a transport protein. A lack of transport of dietary lipids from the intestine to the bloodstream causes malabsorption, which is the main characteristic of the disorder. Malabsorption syndrome with steatorrhea and growth retardation is usually seen in chylomicron retention disease.
Chylomicrons are the transport lipids that primarily involved in carrying of dietary lipids such as triglyceride-rich lipoproteins which are secreted generally from the enterocytes. It is produced in the endoplasmic reticulum of the absorptive cells (enterocytes) of the small intestine. These large lipoproteins range from 700 to 6000 Å size which contains a single molecule of apolipoprotein (apo) B-48. It is a sole molecule, essential for chylomicron structure organization. Apo B-100 is different which is found within very-low-density lipoproteins (VLDL) secreted by the liver and in low-density lipoprotein (LDL), a catabolic product of VLDL.
It is rarely diagnosed in infants presenting with failure to thrive and chronic diarrhea. Malabsorption syndrome with steatorrhea and growth retardation is usually seen in chylomicron retention disease. Steatorrhea is the excretion of abnormal quantities of fat with the feces owing to reduced absorption of fat by the intestine. If not treated, it can cause subsequent neurological impairment. Neurological signs, although variable, consisting most frequently of a loss of reflexes. There is little acanthocytosis (red blood cells appear like thorny), hypocholesterolemia, hypotriglyceridemia, lipid malabsorption, diarrhea, retinitis pigmentosa, and spinocerebellar degeneration are negative of chylomicron retention disease.
Chylomicron retention disease is usually caused by gene mutations, particularly in the SAR1B gene. The SAR1B gene has instruction for Sar1b protein, which is involved in chylomicron transport from the endoplasmic reticulum to the Golgi apparatus. In fact, Sar1-GTP forms a coating protein complex with two heterodimers Sec23/24 and Sec 13/31, which initiates budding and captures cargo to eject vesicles from the endoplasmic reticulum to the Golgi apparatus.
SAR1B gene mutations impair the release of chylomicrons into the bloodstream. A lack of chylomicrons in the blood prevents dietary fats and fat-soluble vitamins from being used by the body, leading to the nutritional and developmental problems seen in people with chylomicron retention disease.
Why Is It Referred To As Autosomal Recessive Pattern?
Chylomicron retention disease is a good example for inherited autosomal recessive pattern. The parents of an individual with an autosomal recessive condition typically do not show any signs or symptoms of the condition. To have an autosomal recessive disorder, entities must inherit two mutated genes, one from each parent. These conditions are commonly passed on by two carriers. Their health is not often pretentious, but they have one mutated gene (recessive gene) and one normal gene (dominant gene) for the condition. With each pregnancy, two carriers have a 25 percent chance of having an unaffected child with two normal genes, a 50 percent chance of having an unaffected child who is also a carrier and a 25 percent chance of having an affected child with two recessive genes.

lowercased:
anderson’s disease is also known as chylomicron retention disease which is a rare hereditary disease. it is an autosomal recessive disease characterized by low plasma lipid and low lipid-soluble vitamins (such as vitamin e and vitamin d). after the digestion of food, lipids, and lipid soluble vitamins are absorbed in the human body with the help of chylomicrons. a lack of chylomicron can interrupt the transport of molecules from intestine to the bloodstream resulting in malabsorption. subjects with these disorders show different clinical manifestations which were initially described by anderson and colleagues, hence it was called as “anderson’s disease”. genotyping has revealed that anderson's and chylomicron retention disease are in fact the same disease.
anderson' disease and chylomicron retention disease is the same disease which has been proved genotypically. the disease is caused by the mutation in the gene sar1b (formerly sara2), which encodes the sar1b protein. mutation results in the defect in chylomicron secretion, a transport protein. a lack of transport of dietary lipids from the intestine to the bloodstream causes malabsorption, which is the main characteristic of the disorder. malabsorption syndrome with steatorrhea and growth retardation is usually seen in chylomicron retention disease.
chylomicrons are the transport lipids that primarily involved in carrying of dietary lipids such as triglyceride-rich lipoproteins which are secreted generally from the enterocytes. it is produced in the endoplasmic reticulum of the absorptive cells (enterocytes) of the small intestine. these large lipoproteins range from 700 to 6000 å size which contains a single molecule of apolipoprotein (apo) b-48. it is a sole molecule, essential for chylomicron structure organization. apo b-100 is different which is found within very-low-density lipoproteins (vldl) secreted by the liver and in low-density lipoprotein (ldl), a catabolic product of vldl.
it is rarely diagnosed in infants presenting with failure to thrive and chronic diarrhea. malabsorption syndrome with steatorrhea and growth retardation is usually seen in chylomicron retention disease. steatorrhea is the excretion of abnormal quantities of fat with the feces owing to reduced absorption of fat by the intestine. if not treated, it can cause subsequent neurological impairment. neurological signs, although variable, consisting most frequently of a loss of reflexes. there is little acanthocytosis (red blood cells appear like thorny), hypocholesterolemia, hypotriglyceridemia, lipid malabsorption, diarrhea, retinitis pigmentosa, and spinocerebellar degeneration are negative of chylomicron retention disease.
chylomicron retention disease is usually caused by gene mutations, particularly in the sar1b gene. the sar1b gene has instruction for sar1b protein, which is involved in chylomicron transport from the endoplasmic reticulum to the golgi apparatus. in fact, sar1-gtp forms a coating protein complex with two heterodimers sec23/24 and sec 13/31, which initiates budding and captures cargo to eject vesicles from the endoplasmic reticulum to the golgi apparatus.
sar1b gene mutations impair the release of chylomicrons into the bloodstream. a lack of chylomicrons in the blood prevents dietary fats and fat-soluble vitamins from being used by the body, leading to the nutritional and developmental problems seen in people with chylomicron retention disease.
why is it referred to as autosomal recessive pattern?
chylomicron retention disease is a good example for inherited autosomal recessive pattern. the parents of an individual with an autosomal recessive condition typically do not show any signs or symptoms of the condition. to have an autosomal recessive disorder, entities must inherit two mutated genes, one from each parent. these conditions are commonly passed on by two carriers. their health is not often pretentious, but they have one mutated gene (recessive gene) and one normal gene (dominant gene) for the condition. with each pregnancy, two carriers have a 25 percent chance of having an unaffected child with two normal genes, a 50 percent chance of having an unaffected child who is also a carrier and a 25 percent chance of having an affected child with two recessive genes.


text: Curran, Vivian Grosswald (2001) "Fear of Formalism: Indications from the Fascist Period in France and Germany of Judicial Methodology’s Impact on Substantive Law," Cornell International Law Journal: Vol. 35 : No. 1 , Article 3.

lowercased: curran, vivian grosswald (2001) "fear of formalism: indications from the fascist period in france and germany of judicial methodology’s impact on substantive law," cornell international law journal: vol. 35 : no. 1 , article 3.


text:
Our Infused Eco Eye Shadow Refills are single unit pans that fit into our eco-friendly Magnetic Eye Shadow Palette. Each Infused Eco Eye Shadow Refill shade is intended to be placed in this Magnetic Eye Shadow Pallet which is sold separately here.
Organic Infused Eco Eye Shadows come in a variety of dynamic shades in serious earth tones, gorgeous jewel tones, and brilliant metallics. So mix and match to create a look that accentuates your natural beauty however dramatic or subtle your mood.
And don’t forget the skin care benefits. This formula, comprised of 65% USDA certified organic botanicals, includes Organic Acai Berry and Organic Goji Berry. These antioxidant and vitamin-rich fruits are known for their ability to protect cells from free radical damage while keeping skin well moisturized.
What’s more? This incredible formula offers long lasting color. So eyes stay perfect all day or night.
Finished with your favorite shade? Simply order a REFILL and reduce your waste!

lowercased:
our infused eco eye shadow refills are single unit pans that fit into our eco-friendly magnetic eye shadow palette. each infused eco eye shadow refill shade is intended to be placed in this magnetic eye shadow pallet which is sold separately here.
organic infused eco eye shadows come in a variety of dynamic shades in serious earth tones, gorgeous jewel tones, and brilliant metallics. so mix and match to create a look that accentuates your natural beauty however dramatic or subtle your mood.
and don’t forget the skin care benefits. this formula, comprised of 65% usda certified organic botanicals, includes organic acai berry and organic goji berry. these antioxidant and vitamin-rich fruits are known for their ability to protect cells from free radical damage while keeping skin well moisturized.
what’s more? this incredible formula offers long lasting color. so eyes stay perfect all day or night.
finished with your favorite shade? simply order a refill and reduce your waste!


text:
A brief while back BMW exposed their all brand-new Le Mans challenger, the M8 GTE. Although the car might not imply much for some, it in fact provides us a respectable concept about exactly what to anticipate from the future 2019 BMW M8. The reports about this car began more than 2 years earlier and at the time everybody believed the car was going to be based upon the i8. Nevertheless, more just recently things altered and BMW essentially verified the M8 will be based upon the 8 Series which will be the coupe variation of the 7 Series. This came as a shock for numerous however it made substantially more sense than using an i8-based M car. Thanks to that, the brand-new M8 can be considered as the spiritual follower to the initial 8 Series, a high efficiency high-end coupe from the ’90s.
Much like with its predecessor, the production M8 is a two-door high-end coupe however there is a lot more to it than simply that. For beginners, the car is now based upon BMW’s all brand-new CLAR architecture which debuted with the brand-new 7 Series. This permits the huge coupe to be fairly light for its size.
On top of that, the platform provides it an extremely stiff chassis which was not possible in the past. This will enable it to use terrific NVH levels and likewise an actually excellent set of driving attributes. The latter will be enhanced with the assistance of its running equipment.
It looks like the 2019 BMW M8 may include a totally adaptive suspension system which is otherwise not available on the 7 Series. This would respond to the roadway ahead and it would prepare the car for the next corner ahead of time.
This system has actually been attempted prior to however up until now it wasn’t actually all that great. The one that will be set up on the 2019 M8 ought to enable it to be substantially faster than its smaller sized brother or sisters while likewise being much heavier.
The upcoming BMW M8 will most likely turn into one of the most pricey BMW lorries ever. Being available in a coupe and convertible variations, this model will require deep pockets. Presently, the most costly Bimmer, tagged with an M, is a M760i xDrive which costs $156,700.
The routine installation of 2019 BMW M8 will be available in comparable style, and at a very same price. The convertible variation will, on the other hand command an amount over $170,000. The reports about an V-12 M8 would press the price limit even further. Most likely in $200 thousand area.
The car will be presented in mid-2018 as 2019 MY. The sales will begin in the fall of the next year.
Although the production model has yet to be exposed, the car was seen checking a while earlier. On top of that, the GTE Le Mans racer provides us a respectable concept about exactly what to anticipate.
From the appearances of it, the brand-new M8 will be a fair bit longer, broader and lower than the comparable 6 Series. In truth it appears like the car will include an enormously long hood which will offer it a truly strong existence on the roadway.
The back is likewise significantly longer than that of the M6 which is rather uncommon on a current car. Completion outcome is a two-door coupe that appears like a real high-end high-end car. the kidney-grilles are still present and the rear tail lights are still just like BMW’s other automobiles. Nevertheless, thanks to its brand-new set of percentages, the 2019 BMW M8 actually handles to impress.
It is safe to presume the production variation of the M8 will be almost similar inside to the present range-topping 7 Series. The car’s control panel will be the exact same however it appears like the instrument cluster and perhaps the iDrive system may be various.
On top of that, being a high efficiency variation, the M8 will likewise include distinct seats with bigger side reinforces and more adjustability alternatives. Some reports likewise stated the car was going to include simply 2 seats however considering its size, this is extremely not likely.
GTE-class engines are really restricted to 4.0 liters in displacement, so the M8 GTE includes simply a 4.0 liter engine. Most reports appear to recommend the production 2019 BMW M8 will include a 4.4 liter twin-turbocharged V8 which will supply over 600 horse power and 600 lb-ft of torque.
Up until now the German producer chose to remain peaceful about this however things might not be exactly what they appear. Despite the fact that up until now most BMW’s V8s were 4.4 liters in displacement, the brand-new generation of engines may be smaller sized, more effective and more effective.
On top of that, launching a 4.0 liter engine would be much easier for them as they would have the ability to utilize among their modular cylinder styles. This would reduce production expenses and it would enable the M8 to be much faster and much better to drive as the smaller sized engine would likewise be lighter.

lowercased:
a brief while back bmw exposed their all brand-new le mans challenger, the m8 gte. although the car might not imply much for some, it in fact provides us a respectable concept about exactly what to anticipate from the future 2019 bmw m8. the reports about this car began more than 2 years earlier and at the time everybody believed the car was going to be based upon the i8. nevertheless, more just recently things altered and bmw essentially verified the m8 will be based upon the 8 series which will be the coupe variation of the 7 series. this came as a shock for numerous however it made substantially more sense than using an i8-based m car. thanks to that, the brand-new m8 can be considered as the spiritual follower to the initial 8 series, a high efficiency high-end coupe from the ’90s.
much like with its predecessor, the production m8 is a two-door high-end coupe however there is a lot more to it than simply that. for beginners, the car is now based upon bmw’s all brand-new clar architecture which debuted with the brand-new 7 series. this permits the huge coupe to be fairly light for its size.
on top of that, the platform provides it an extremely stiff chassis which was not possible in the past. this will enable it to use terrific nvh levels and likewise an actually excellent set of driving attributes. the latter will be enhanced with the assistance of its running equipment.
it looks like the 2019 bmw m8 may include a totally adaptive suspension system which is otherwise not available on the 7 series. this would respond to the roadway ahead and it would prepare the car for the next corner ahead of time.
this system has actually been attempted prior to however up until now it wasn’t actually all that great. the one that will be set up on the 2019 m8 ought to enable it to be substantially faster than its smaller sized brother or sisters while likewise being much heavier.
the upcoming bmw m8 will most likely turn into one of the most pricey bmw lorries ever. being available in a coupe and convertible variations, this model will require deep pockets. presently, the most costly bimmer, tagged with an m, is a m760i xdrive which costs $156,700.
the routine installation of 2019 bmw m8 will be available in comparable style, and at a very same price. the convertible variation will, on the other hand command an amount over $170,000. the reports about an v-12 m8 would press the price limit even further. most likely in $200 thousand area.
the car will be presented in mid-2018 as 2019 my. the sales will begin in the fall of the next year.
although the production model has yet to be exposed, the car was seen checking a while earlier. on top of that, the gte le mans racer provides us a respectable concept about exactly what to anticipate.
from the appearances of it, the brand-new m8 will be a fair bit longer, broader and lower than the comparable 6 series. in truth it appears like the car will include an enormously long hood which will offer it a truly strong existence on the roadway.
the back is likewise significantly longer than that of the m6 which is rather uncommon on a current car. completion outcome is a two-door coupe that appears like a real high-end high-end car. the kidney-grilles are still present and the rear tail lights are still just like bmw’s other automobiles. nevertheless, thanks to its brand-new set of percentages, the 2019 bmw m8 actually handles to impress.
it is safe to presume the production variation of the m8 will be almost similar inside to the present range-topping 7 series. the car’s control panel will be the exact same however it appears like the instrument cluster and perhaps the idrive system may be various.
on top of that, being a high efficiency variation, the m8 will likewise include distinct seats with bigger side reinforces and more adjustability alternatives. some reports likewise stated the car was going to include simply 2 seats however considering its size, this is extremely not likely.
gte-class engines are really restricted to 4.0 liters in displacement, so the m8 gte includes simply a 4.0 liter engine. most reports appear to recommend the production 2019 bmw m8 will include a 4.4 liter twin-turbocharged v8 which will supply over 600 horse power and 600 lb-ft of torque.
up until now the german producer chose to remain peaceful about this however things might not be exactly what they appear. despite the fact that up until now most bmw’s v8s were 4.4 liters in displacement, the brand-new generation of engines may be smaller sized, more effective and more effective.
on top of that, launching a 4.0 liter engine would be much easier for them as they would have the ability to utilize among their modular cylinder styles. this would reduce production expenses and it would enable the m8 to be much faster and much better to drive as the smaller sized engine would likewise be lighter.


text:
Did you know that The FamiLee Jewels does home parties? Invite your friends to your home for a couple of hours. We will bring our jewelry creations to you and show them to you in the comfort of your own home. Try on your favorite pieces, wear them for the afternoon or evening, and fall in love with our jewelry. Find the perfect gem for that new outfit or special event.
A VIP card that entitles you to 10% off future purchases from the FamiLee Jewels for 1 year.
When one of your guests books a show and holds it within 6 months you will receive a coupon that can be used at that show.
If your guest sales total 200$ you will receive 25$ in free product.
If your guest sales total 300$ you will receive 40$ in free product.
If your guest sales total 400$ you will receive 60$ in free product.
If your guest sales total 500$ you will receive 90$ in free product.
If your guest sales total 750$ you will receive 150$ in free product and 25% off 1 item.
If your guest sales total 1000$ you will receive 200$ in free product and 50% off 1 item.
If your guest sales total 1500$ and above you will receive 200$ in free product, 50% off 2 items, and The FamiLee Jewels Artisan of your choice will work with you to design a piece to your specifications up to 100$ value.
The simplest of all shows is an open house. Requiring little to no fuss, you invite us into your home to set up our displays. Then invite your friends, family members, neighbors and coworkers over to shop.
The trunk show is the classic style of home party. We will bring our merchandise to you and give an informal presentation that teaches you a bit about the gemstones and design styles that we use. If you are interested in particular stones or styles, we can tailor the evening to showcase your favorites.
For a fee of $25 per guest we will teach your friends the basics of bead stringing. Each guest will complete a single strand necklace and pair of earrings of their own. We will provide all of the necessary beads, findings, stringing materials and tools. Beginner level kits will be available for purchase if your guests want to pursue their new jewelry skills. If you so choose we can also bring a selection of jewelry for sale.
For the crème de la crème treat yourself and your guests to a custom jewelry party. We will bring our gemstones, beads, wire, findings and design tables and will work with you to create the piece of your dreams. Jewelry will be completed and delivered to the host within 2 weeks time.
You are welcome to hold a home party as a fundraiser for your charity of choice. For fundraising purposes The FamiLee Jewels will donate 15% of total sales to your designated charity.

lowercased:
did you know that the familee jewels does home parties? invite your friends to your home for a couple of hours. we will bring our jewelry creations to you and show them to you in the comfort of your own home. try on your favorite pieces, wear them for the afternoon or evening, and fall in love with our jewelry. find the perfect gem for that new outfit or special event.
a vip card that entitles you to 10% off future purchases from the familee jewels for 1 year.
when one of your guests books a show and holds it within 6 months you will receive a coupon that can be used at that show.
if your guest sales total 200$ you will receive 25$ in free product.
if your guest sales total 300$ you will receive 40$ in free product.
if your guest sales total 400$ you will receive 60$ in free product.
if your guest sales total 500$ you will receive 90$ in free product.
if your guest sales total 750$ you will receive 150$ in free product and 25% off 1 item.
if your guest sales total 1000$ you will receive 200$ in free product and 50% off 1 item.
if your guest sales total 1500$ and above you will receive 200$ in free product, 50% off 2 items, and the familee jewels artisan of your choice will work with you to design a piece to your specifications up to 100$ value.
the simplest of all shows is an open house. requiring little to no fuss, you invite us into your home to set up our displays. then invite your friends, family members, neighbors and coworkers over to shop.
the trunk show is the classic style of home party. we will bring our merchandise to you and give an informal presentation that teaches you a bit about the gemstones and design styles that we use. if you are interested in particular stones or styles, we can tailor the evening to showcase your favorites.
for a fee of $25 per guest we will teach your friends the basics of bead stringing. each guest will complete a single strand necklace and pair of earrings of their own. we will provide all of the necessary beads, findings, stringing materials and tools. beginner level kits will be available for purchase if your guests want to pursue their new jewelry skills. if you so choose we can also bring a selection of jewelry for sale.
for the crème de la crème treat yourself and your guests to a custom jewelry party. we will bring our gemstones, beads, wire, findings and design tables and will work with you to create the piece of your dreams. jewelry will be completed and delivered to the host within 2 weeks time.
you are welcome to hold a home party as a fundraiser for your charity of choice. for fundraising purposes the familee jewels will donate 15% of total sales to your designated charity.


text:
A new special report from Microgrid Knowledge and NRG Energy explores trends in local energy and distributed energy resources (DERs). This excerpt takes a look at how market factors have led to the maturity of DER technology.
Distributed energy used to be simple. Put a generator in a building basement, or solar panels on a roof, and the job was done.
But today’s DERs do more than produce generation. As microgrids demonstrate, they’ve become sophisticated management tools for complex combinations of energy resources and can provide a range of new price, environmental and system efficiency benefits.
How did this growth in digital intelligence and management capability come about?
The path to smart DER technology started a couple decades ago when demand response was a relatively new tool to curtail peak demand on an overtaxed power system. Early on, interruptible rates served as a key enabler for demand response, providing incentives for customers to reduce electricity use. In that scenario, curtailment was driven by radio controls and pagers, relatively primitive technology by today’s standards. As electronics and controls advanced, demand response systems became capable of more automated and precise two-way communications between the grid and individual devices, or loads, on the system.
Technological advances in DER technology and their controls, combined with key regulatory changes, spurred further innovation and opened new markets in demand response.
Organizations began to realize they also could participate in demand response programs by combining a backup generation source with battery storage and linking them together with advanced electronic controls. Rather than reduce business operations or dim lighting, they could instead curtail use of grid power with an on-site generator. From the grid operator’s perspective, the action produces the same result— the customer consumes less power when the grid is overtaxed.
This approach also opened a new way to minimize utility demand charges. Such charges can be onerous for large energy users because they are set based on their electric usage during a high-cost peak period. By reducing usage at the right time, the organization could lower the charges. Operating on-site generators during this time is one way to do so.
The next step was to use more than one generation resource and manage them for greatest economic flexibility. An early microgrid—although it wasn’t yet called that—tended to use a CHP plant that could operate either independently or connected to the grid. Another variation paired the CHP plant with a second form of generation, often a fossil fuel backup generator.
Later, solar photovoltaics and sometimes wind turbines began to appear in the microgrid generation mix. This trend intensified with a decline in renewable energy costs, coupled with the drive by organizations to achieve sustainability goals.
Distributed resources plans (DRPs) can lay the groundwork for integrating DERs into a utility’s grid, by delineating hosting capacity on the grid, providing locational values for DERs and streamlining interconnection procedures.
Energy storage became the latest addition as battery prices fell. Batteries also proved to be effective energy management tools, charged when electricity prices are low and discharged when prices are high. While batteries are the most common form of storage, a microgrid may also use thermal storage, which can employ a range of mediums such as ice, earth and concrete, to capture and store heating and cooling.
A market research report from Deutsche Bank predicts that in 2018, the amount of new distributed generation may exceed the amount of new central generation globally. The report estimates that the current 1 GW DER market could grow to over 40 GW by 2022, and by 2023 distributed generation could supplant the need for 320 GW of large-scale power plants. The increase in DERs will, in turn, drive the need for intelligent distribution networks comprised of nanogrids, microgrids and virtual power plants, according to the report.
Despite their growth, DERs and microgrids face barriers to wider adoption. For example, a microgrid with only diesel generators may risk exceeding legal emissions limits if it runs too long. Financial and regulatory barriers in certain cases may also inhibit DER adoption. Expert opinion varies on the relative importance of those barriers.
Sixty-one percent of utility executives identified capital and financial constraints as the top barrier to DER adoption.
Only 46 percent of those executives identified regulations as a barrier.
Sixty-one percent of regulators identified inadequate regulations as the top barrier.
Only 33 percent of the regulators saw capital and financial constraints as a problem.
This gap in perception highlights some of the challenges the microgrid industry faces in prioritizing reforms that will lead to wider adoption of DER technology.
On the financial side, the lack of long-term off-take contracts raises concern. Much of the wholesale electric power in the U.S. is bought and sold on the short-term or spot market, an arena sometimes long on volatility and short on revenue that financiers seek.
On the regulatory front, many states lack clear policies on DER integration with the grid. That’s starting to change. Several states, notably California and New York, have adopted policies aimed at DER integration. Similar policies have also been put in place at the federal level with more in the works.
Formal state requirements for utility adoption of distributed resources plans (DRPs) also assists DER development. DRPs can lay the groundwork for integrating DERs into a utility’s grid, by delineating hosting capacity on the grid, providing locational values for DERs and streamlining interconnection procedures. In a white paper, the Lawrence Berkeley National Laboratory noted that eight states have adopted some form of DRP requirement for their investor-owned utilities.
Microgrids and DERs have come of age, offering sophisticated technology and services that energy users both need and want. It is now a matter of regulation, markets and business models catching up. As we’ll see in the next three chapters, this is already happening.
For more on the rise of local energy, see the new special report, “The Evolution of Distributed Energy Resources What the Rise of Local Energy Means for Businesses, Institutions and Communities,” courtesy of NRG, downloadable free of charge.
are there any 48volt DC DERs?

lowercased:
a new special report from microgrid knowledge and nrg energy explores trends in local energy and distributed energy resources (ders). this excerpt takes a look at how market factors have led to the maturity of der technology.
distributed energy used to be simple. put a generator in a building basement, or solar panels on a roof, and the job was done.
but today’s ders do more than produce generation. as microgrids demonstrate, they’ve become sophisticated management tools for complex combinations of energy resources and can provide a range of new price, environmental and system efficiency benefits.
how did this growth in digital intelligence and management capability come about?
the path to smart der technology started a couple decades ago when demand response was a relatively new tool to curtail peak demand on an overtaxed power system. early on, interruptible rates served as a key enabler for demand response, providing incentives for customers to reduce electricity use. in that scenario, curtailment was driven by radio controls and pagers, relatively primitive technology by today’s standards. as electronics and controls advanced, demand response systems became capable of more automated and precise two-way communications between the grid and individual devices, or loads, on the system.
technological advances in der technology and their controls, combined with key regulatory changes, spurred further innovation and opened new markets in demand response.
organizations began to realize they also could participate in demand response programs by combining a backup generation source with battery storage and linking them together with advanced electronic controls. rather than reduce business operations or dim lighting, they could instead curtail use of grid power with an on-site generator. from the grid operator’s perspective, the action produces the same result— the customer consumes less power when the grid is overtaxed.
this approach also opened a new way to minimize utility demand charges. such charges can be onerous for large energy users because they are set based on their electric usage during a high-cost peak period. by reducing usage at the right time, the organization could lower the charges. operating on-site generators during this time is one way to do so.
the next step was to use more than one generation resource and manage them for greatest economic flexibility. an early microgrid—although it wasn’t yet called that—tended to use a chp plant that could operate either independently or connected to the grid. another variation paired the chp plant with a second form of generation, often a fossil fuel backup generator.
later, solar photovoltaics and sometimes wind turbines began to appear in the microgrid generation mix. this trend intensified with a decline in renewable energy costs, coupled with the drive by organizations to achieve sustainability goals.
distributed resources plans (drps) can lay the groundwork for integrating ders into a utility’s grid, by delineating hosting capacity on the grid, providing locational values for ders and streamlining interconnection procedures.
energy storage became the latest addition as battery prices fell. batteries also proved to be effective energy management tools, charged when electricity prices are low and discharged when prices are high. while batteries are the most common form of storage, a microgrid may also use thermal storage, which can employ a range of mediums such as ice, earth and concrete, to capture and store heating and cooling.
a market research report from deutsche bank predicts that in 2018, the amount of new distributed generation may exceed the amount of new central generation globally. the report estimates that the current 1 gw der market could grow to over 40 gw by 2022, and by 2023 distributed generation could supplant the need for 320 gw of large-scale power plants. the increase in ders will, in turn, drive the need for intelligent distribution networks comprised of nanogrids, microgrids and virtual power plants, according to the report.
despite their growth, ders and microgrids face barriers to wider adoption. for example, a microgrid with only diesel generators may risk exceeding legal emissions limits if it runs too long. financial and regulatory barriers in certain cases may also inhibit der adoption. expert opinion varies on the relative importance of those barriers.
sixty-one percent of utility executives identified capital and financial constraints as the top barrier to der adoption.
only 46 percent of those executives identified regulations as a barrier.
sixty-one percent of regulators identified inadequate regulations as the top barrier.
only 33 percent of the regulators saw capital and financial constraints as a problem.
this gap in perception highlights some of the challenges the microgrid industry faces in prioritizing reforms that will lead to wider adoption of der technology.
on the financial side, the lack of long-term off-take contracts raises concern. much of the wholesale electric power in the u.s. is bought and sold on the short-term or spot market, an arena sometimes long on volatility and short on revenue that financiers seek.
on the regulatory front, many states lack clear policies on der integration with the grid. that’s starting to change. several states, notably california and new york, have adopted policies aimed at der integration. similar policies have also been put in place at the federal level with more in the works.
formal state requirements for utility adoption of distributed resources plans (drps) also assists der development. drps can lay the groundwork for integrating ders into a utility’s grid, by delineating hosting capacity on the grid, providing locational values for ders and streamlining interconnection procedures. in a white paper, the lawrence berkeley national laboratory noted that eight states have adopted some form of drp requirement for their investor-owned utilities.
microgrids and ders have come of age, offering sophisticated technology and services that energy users both need and want. it is now a matter of regulation, markets and business models catching up. as we’ll see in the next three chapters, this is already happening.
for more on the rise of local energy, see the new special report, “the evolution of distributed energy resources what the rise of local energy means for businesses, institutions and communities,” courtesy of nrg, downloadable free of charge.
are there any 48volt dc ders?


text:
INSTAF provides full negotiation and renegotiation services according to your needs. Develops negotiation strategies for negotiations which are usually centered around distribution, price, production, time or quality issues. Negotiates for Governments, Corporations, Organizations and Individuals in a wide variety of conflicts/disputes that they would rather negotiate than litigate.
Negotiations have to be well prepared. Objectives, alternatives and the status quo have to be to defined and the strategic situation has to be analyzed. A precise diagnosis leads to a successful therapy.
INSTAF Negotiation Advisory Sevices is a competitive advantage and will lead to business success.
The success of all commercial negotiations depends on the understanding of the nine stage negotiation process and a professional negotiation management. As experienced, global negotiation experts, INSTAF works with their clients as part of their team in all stages of a negotiation. INSTAF Experts cover all commercial negotiation situations across all sectors, industries, and markets.

lowercased:
instaf provides full negotiation and renegotiation services according to your needs. develops negotiation strategies for negotiations which are usually centered around distribution, price, production, time or quality issues. negotiates for governments, corporations, organizations and individuals in a wide variety of conflicts/disputes that they would rather negotiate than litigate.
negotiations have to be well prepared. objectives, alternatives and the status quo have to be to defined and the strategic situation has to be analyzed. a precise diagnosis leads to a successful therapy.
instaf negotiation advisory sevices is a competitive advantage and will lead to business success.
the success of all commercial negotiations depends on the understanding of the nine stage negotiation process and a professional negotiation management. as experienced, global negotiation experts, instaf works with their clients as part of their team in all stages of a negotiation. instaf experts cover all commercial negotiation situations across all sectors, industries, and markets.


text:
she's too pretty for words!
^ I know! I am so jealous of her, shes so beautiful!
I like that she's got a solid head on her shoulders and she isn't arrogant or showy. Loved her in Star Wars.
I am a huge Indiana Jones fan, I have been waiting for this new movie for what feels like 5 years already. it has been in talk FOREVER, any new news is good news!!!
she's beautiful and intelligent, what a combination.
I love her at the end of the movie "Closer"...she must be way more stunning IRL , the guys were giving her second,third look. It was shot in the crowded street.
She can look pretty when bald. I don't think I can!
she looks really gorgeous here. can't wait for my issue to arrive!
i'm def picking that up when it hits the stands.

lowercased:
she's too pretty for words!
^ i know! i am so jealous of her, shes so beautiful!
i like that she's got a solid head on her shoulders and she isn't arrogant or showy. loved her in star wars.
i am a huge indiana jones fan, i have been waiting for this new movie for what feels like 5 years already. it has been in talk forever, any new news is good news!!!
she's beautiful and intelligent, what a combination.
i love her at the end of the movie "closer"...she must be way more stunning irl , the guys were giving her second,third look. it was shot in the crowded street.
she can look pretty when bald. i don't think i can!
she looks really gorgeous here. can't wait for my issue to arrive!
i'm def picking that up when it hits the stands.


text:
Image Title: 7684 OS3 Rue De Lyon Home Office Executive Suite DMI With Regard To Furniture Prepare 8. Filename: 7684-os3-rue-de-lyon-home-office-executive-suite-dmi-with-regard-to-furniture-prepare-8.jpg. Image Dimension: 500 x 500 pixels. Images Format: jpg/jpeg. Publisher/Author: Norris Jones. Uploaded Date: Sunday - May 20th. 2018 05:41:26 AM. Category: Architecture. Image Source: bhg.com.
Tap The Thumbnail Bellow to See Related Gallery of "7684 OS3 Rue De Lyon Home Office Executive Suite DMI With Regard To Furniture Prepare 8"

lowercased:
image title: 7684 os3 rue de lyon home office executive suite dmi with regard to furniture prepare 8. filename: 7684-os3-rue-de-lyon-home-office-executive-suite-dmi-with-regard-to-furniture-prepare-8.jpg. image dimension: 500 x 500 pixels. images format: jpg/jpeg. publisher/author: norris jones. uploaded date: sunday - may 20th. 2018 05:41:26 am. category: architecture. image source: bhg.com.
tap the thumbnail bellow to see related gallery of "7684 os3 rue de lyon home office executive suite dmi with regard to furniture prepare 8"


text: SS August 20/08, Offers August 25/08, Evening. Long time owner of this great character home on a fantastic street, Features 1 3/4 storeys, 3 spacious bedrooms + a den. 2 baths. Original oak woodwork throughout, Hardwood floors under some carpets, Large Dining Rm, Open Living Rm complete with brick facing gas fireplace & original built-in cabinets. Fantastic front porch for those warm summer nights. Full Basement with den and 2nd Bath. Oversized double garage with opener. Extra parking, fenced yard. Don't miss it!

lowercased: ss august 20/08, offers august 25/08, evening. long time owner of this great character home on a fantastic street, features 1 3/4 storeys, 3 spacious bedrooms + a den. 2 baths. original oak woodwork throughout, hardwood floors under some carpets, large dining rm, open living rm complete with brick facing gas fireplace & original built-in cabinets. fantastic front porch for those warm summer nights. full basement with den and 2nd bath. oversized double garage with opener. extra parking, fenced yard. don't miss it!


text:
These fantastic Kiko frames are a beautiful way to display photographs and keepsakes. Their brass frames simply add to their elegance. Choose from portrait and landscape apertures or mix it up with both!
Colour: Brass (Sari tie colour varies).

lowercased:
these fantastic kiko frames are a beautiful way to display photographs and keepsakes. their brass frames simply add to their elegance. choose from portrait and landscape apertures or mix it up with both!
colour: brass (sari tie colour varies).


text: Hillary’s culpability and her flouting of the law now seem clear. But that leaves one more shoe to drop: Will Attorney General Loretta Lynch indict the Democrats’ presumptive presidential nominee? If she doesn’t, she’ll need a good excuse why.

lowercased: hillary’s culpability and her flouting of the law now seem clear. but that leaves one more shoe to drop: will attorney general loretta lynch indict the democrats’ presumptive presidential nominee? if she doesn’t, she’ll need a good excuse why.


text: The 6th essential to optimal health and wellness is to remove chemical stress. Our bodies are constantly bombarded with toxins from the food we eat, the air we breathe, household cleaners, personal care products etc. In order for us to achieve optimal health and to get the greatest benefit from our weekly spinal re-engineering adjustments we must remove these toxins. Of course we want to limit the intake of toxins by eating right and using better products, but it is impossible to avoid 100% of them. That’s why we recommend doing the Maximized Living daily detox or the Standard Process 21 day cleanse twice a year.

lowercased: the 6th essential to optimal health and wellness is to remove chemical stress. our bodies are constantly bombarded with toxins from the food we eat, the air we breathe, household cleaners, personal care products etc. in order for us to achieve optimal health and to get the greatest benefit from our weekly spinal re-engineering adjustments we must remove these toxins. of course we want to limit the intake of toxins by eating right and using better products, but it is impossible to avoid 100% of them. that’s why we recommend doing the maximized living daily detox or the standard process 21 day cleanse twice a year.


text: If you work with medical data and need to comply with HIPAA regulations (specifically 21 CFR Part 11 regulations), Troi Encryptor Plug-in 5.0 and FileMaker Pro 17 can help you accomplish just that. The FileMaker Pro database can store your information and Troi Encryptor Plug-in can encrypt sensitive information using powerful 256-bit AES encryption. You then have full control which information is made visilble on a record or even field level. Also secure exchange of data with other systems or websites is possible, via OpenSSL and PHP 7 for example.

lowercased: if you work with medical data and need to comply with hipaa regulations (specifically 21 cfr part 11 regulations), troi encryptor plug-in 5.0 and filemaker pro 17 can help you accomplish just that. the filemaker pro database can store your information and troi encryptor plug-in can encrypt sensitive information using powerful 256-bit aes encryption. you then have full control which information is made visilble on a record or even field level. also secure exchange of data with other systems or websites is possible, via openssl and php 7 for example.


text:
Sewing Rooms To Die For!
Look at this vibrant and happy sewing room! Table is from a restaurant supply, rug from Ikea, cabinet from Ikea and the curtains Diane made!
Wouldn't you just love to have this expansive space for your own sewing room? It has everything but the fridge! Tom Volk made the hanging wall storage, ironing table, the cutting table and the sewing area along the back wall..
Please send us pictures of your sewing room!
This could be YOUR name HERE!
Dana Lynch's Innova all set up in her room.
YOUR sewing room could be featured HERE!

lowercased:
sewing rooms to die for!
look at this vibrant and happy sewing room! table is from a restaurant supply, rug from ikea, cabinet from ikea and the curtains diane made!
wouldn't you just love to have this expansive space for your own sewing room? it has everything but the fridge! tom volk made the hanging wall storage, ironing table, the cutting table and the sewing area along the back wall..
please send us pictures of your sewing room!
this could be your name here!
dana lynch's innova all set up in her room.
your sewing room could be featured here!