Houda Yasmine Ali Moussa,Kyung Chul Shin,Janarthanan Ponraj,Soo Jin Kim,Je‐Kyung Ryu,Said Mansour,Yongsoo Park
Requirement of Cholesterol for Calcium‐Dependent Vesicle Fusion by Strengthening Synaptotagmin‐1‐Induced Membrane Bending (Adv. Sci. 15/2023)
Vesicle Fusion In article number 2206823, using the bottom‐up synthetic reconstitution, electron microscopy, and in‐vivo amperometry, Yongsoo Park and co‐workers show novel mechanisms of vesicle fusion triggered by calcium ions. Cholesterol stabilizes the local membrane bending induced by synaptotagmin‐1 insertion, thereby lowering the energy barrier for Ca2+‐dependent fusion to occur.
Requirement of Cholesterol for Calcium‐Dependent Vesicle Fusion by Strengthening Synaptotagmin‐1‐Induced Membrane Bending (Adv. Sci. 15/2023)

Vesicle Fusion In article number 2206823, using the bottom‐up synthetic reconstitution, electron microscopy, and in‐vivo amperometry, Yongsoo Park and co‐workers show novel mechanisms of vesicle fusion triggered by calcium ions. Cholesterol stabilizes the local membrane bending induced by synaptotagmin‐1 insertion, thereby lowering the energy barrier for Ca2+‐dependent fusion to occur.