50355
document
Poor self-rated health is not associated with a high total allostatic load in type 2 diabetic patients -- but high blood pressure is . OBJECTIVE Allostatic load has been linked to self-rated health ( SRH ) , cardiovascular disease and mortality in non-diabetic individuals . The aim of this study was to construct an allostatic load score and to find any correlations with SRH . METHODS The subjects included in the study came from a randomized , controlled trial of type 2 diabetes . Blood samples were drawn , urine was collected for 24h , and questionnaires , including SRH , were filled out on three occasions : at baseline ; after the 10-week intervention ; and at a follow-up 3 months after the intervention . Allostatic load was estimated using a wide range of variables , including systolic and diastolic blood pressure , pulse pressure , cortisol , catecholamines , HbA ( 1c ) , insulin , plasma glucose and waist circumference . RESULTS There was no association between SRH and allostatic load . However , three other components were significantly correlated with allostatic load at the baseline investigation and the two follow-up investigations - namely , systolic blood pressure , diastolic blood pressure and HbA ( 1c ) . CONCLUSION The absence of an association between allostatic load and SRH in diabetic individuals contrasts with previous findings in non-diabetic women , and shows that it is hazardous to apply findings in one population to another , especially diabetic and non-diabetic populations .
50356
Outcome_Physical
systolic and diastolic blood pressure , pulse pressure , cortisol , catecholamines , HbA ( 1c ) , insulin , plasma glucose and waist circumference .
50357
Outcome_Physical
systolic blood pressure , diastolic blood pressure and HbA ( 1c ) .
50358
Outcome_Physical
SRH