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document
Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger 's disorders . Autism is a neurodevelopmental disorder characterized by dysfunction in three core behavioral domains : repetitive behaviors , social deficits , and language abnormalities . There is evidence that abnormalities exist in peptide systems , particularly the oxytocin system , in autism spectrum patients . Furthermore , oxytocin and the closely related peptide vasopressin are known to play a role in social and repetitive behaviors . This study examined the impact of oxytocin on repetitive behaviors in 15 adults with autism or Asperger 's disorder via randomized double-blind oxytocin and placebo challenges . The primary outcome measure was an instrument rating six repetitive behaviors : need to know , repeating , ordering , need to tell/ask , self-injury , and touching . Patients with autism spectrum disorders showed a significant reduction in repetitive behaviors following oxytocin infusion in comparison to placebo infusion . Repetitive behavior in autism spectrum disorders may be related to abnormalities in the oxytocin system , and may be partially ameliorated by synthetic oxytocin infusion .
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Intervention_Pharmacological
Oxytocin infusion
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Intervention_Pharmacological
oxytocin
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Intervention_Pharmacological
oxytocin
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Intervention_Control
placebo
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Outcome_Mental
repetitive behaviors
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Outcome_Mental
repetitive behaviors
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Outcome_Mental
repetitive behaviors
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Outcome_Mental
six repetitive behaviors : need to know , repeating , ordering , need to tell/ask , self-injury , and touching .
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Outcome_Mental
repetitive behaviors
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Outcome_Mental
Repetitive behavior
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Participant_Age
adults
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Participant_Condition
autistic and Asperger 's disorders
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Participant_Condition
autism spectrum