64988
document
Salivary testosterone and immunoglobulin A were increased by resistance training in adults with Down syndrome . This study was designed to assess the influence of resistance training on salivary immunoglobulin A ( IgA ) levels and hormone profile in sedentary adults with Down syndrome ( DS ) . A total of 40 male adults with DS were recruited for the trial through different community support groups for people with intellectual disabilities . All participants had medical approval for participation in physical activity . Twenty-four adults were randomly assigned to perform resistance training in a circuit with six stations , 3 days per week for 12 weeks . Training intensity was based on functioning in the eight-repetition maximum ( 8RM ) test for each exercise . The control group included 16 age- , gender- , and BMI-matched adults with DS . Salivary IgA , testosterone , and cortisol levels were measured by ELISA . Work task performance was assessed using the repetitive weighted-box-stacking test . Resistance training significantly increased salivary IgA concentration ( P=0.0120 ; d=0.94 ) and testosterone levels ( P=0.0088 ; d=1.57 ) in the exercising group . Furthermore , it also improved work task performance . No changes were seen in the controls who had not exercised . In conclusion , a short-term resistance training protocol improved mucosal immunity response as well as salivary testosterone levels in sedentary adults with DS .
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Intervention_Educational
resistance training
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Intervention_Educational
resistance training
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Intervention_Physical
exercise
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Intervention_Educational
resistance training
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Outcome_Physical
Salivary IgA
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Outcome_Physical
testosterone
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Outcome_Physical
cortisol levels
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Outcome_Physical
salivary IgA concentration
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Outcome_Physical
testosterone levels
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Outcome_Other
improved work task performance
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Outcome_Physical
immunity response
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Outcome_Physical
salivary testosterone
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Participant_Age
adults
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Participant_Condition
Down syndrome
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Participant_Age
adults
65004
Participant_Condition
Down syndrome ( DS )
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Participant_Sample-size
40
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Participant_Sex
male
65007
Participant_Age
adults
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Participant_Condition
people with intellectual disabilities
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Participant_Condition
participants had medical approval for participation in physical activity
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Participant_Sample-size
Twenty-four
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Participant_Age
adults
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Participant_Age
age-
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Participant_Sex
gender-
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Participant_Age
adults
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Participant_Condition
DS
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Participant_Age
adults
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Participant_Condition
DS