76921
document
Butorphanol and meperidine compared in patients with acute ureteral colic . Pain relief was evaluated in 81 patients with acute ureteral colic and the confirmed presence of a calculus . A randomized double-blind comparison of intramuscular 2 and 4 mg. butorphanol and 80 mg. meperidine was used . Pain intensity and pain relief were evaluated at half hour and hourly intervals for 4 hours . A 2 mg. dose of butorphanol was found to be analgesically equivalent to 80 mg. meperidine , while a 4 mg. dose of butorphanol was found to be more effective than 80 mg. meperidine and 2 mg. butorphanol . Each patient received up to 2 doses of analgesic medication when necessary . There was no significant difference in the incidence of side effects among treatments . One patient had visual hallucinations after a 2 mg. dose of butorphanol , possibly owing to its antagonistic activity to significant narcotic experience given previously at another hospital . There was no other evidence of toxicity with butorphanol . It was found to be a safe , effective and wall tolerated drug for the treatment of ureteral colic and is recommended in place of narcotics .
76922
Intervention_Pharmacological
Butorphanol
76923
Intervention_Pharmacological
meperidine
76924
Intervention_Pharmacological
butorphanol
76925
Intervention_Pharmacological
meperidine
76926
Intervention_Pharmacological
butorphanol
76927
Intervention_Pharmacological
meperidine
76928
Intervention_Pharmacological
butorphanol
76929
Intervention_Pharmacological
meperidine
76930
Intervention_Pharmacological
butorphanol
76931
Intervention_Pharmacological
butorphanol
76932
Intervention_Pharmacological
butorphanol
76933
Outcome_Pain
Pain intensity
76934
Outcome_Pain
pain relief
76935
Outcome_Adverse-effects
incidence of side effects
76936
Outcome_Physical
visual hallucinations
76937
Outcome_Other
toxicity
76938
Outcome_Other
safe , effective and wall tolerated
76939
Participant_Condition
acute ureteral colic
76940
Participant_Sample-size
81
76941
Participant_Condition
acute ureteral colic