73714
document
[ Preventive use of Pentaglobin in intensive care treatment of trauma patients ] . Basing on 50 posttraumatic intensive-care patients with medium grade lesions ( ISS criteria ) , the prophylactic effect of an intravenously applicable IgM preparation ( Pentaglobin ) against nosocomial infections was investigated . The prophylaxis group received on the 3rd , 4th and 5th day a daily dose of 10 g each . At the same times the controls were given 12.5 g human albumin each . Whereas no difference was seen between both groups regarding the definitive outcome of the treatment , the prophylaxis group clearly showed fewer infection pointers during the clinical course . In particular , the incidence and magnitude of febrile temperatures were significantly lower between the 4th and 8th days of treatment . Our results indicate , however , that the prophylactic use those patients who are at particularly high infection exposure risk , e.g . through reintervention surgery , haemorrhage complications or extensive diagnostic interventions .
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Intervention_Pharmacological
Pentaglobin
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Intervention_Pharmacological
Pentaglobin
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Intervention_Pharmacological
12.5 g human albumin
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Outcome_Physical
infections
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Outcome_Physical
infection pointers
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Outcome_Physical
incidence and magnitude of febrile temperatures
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Outcome_Physical
reintervention surgery , haemorrhage complications
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Outcome_Physical
extensive diagnostic interventions
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Participant_Condition
trauma
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Participant_Sample-size
50
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Participant_Condition
posttraumatic intensive-care
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Participant_Condition
lesions
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Participant_Condition
ISS criteria
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Participant_Condition
infection
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Participant_Condition
reintervention surgery
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Participant_Condition
haemorrhage complications
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Participant_Condition
diagnostic interventions