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document
PRL-8-53 : enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent . The effect of 3- ( 2-benzylmethylaminoethyl ) benzoic acid methyl ester hydrochloride ( PRL-8-53 ) on learning and on retention of verbal information in human subjects was investigated . Using the serial anticipation method under double-blind conditions it was found that PRL-8-53 causes slight improvement of acquisition . Retinetion of verbal information was found improved to a statistically significant degree ( most P values better than 0.01 , some better than 0.001 ) . No significant changes were found for either visual reaction time or motor control after drug when compared with placebo values .
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Intervention_Pharmacological
PRL-8-53
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Intervention_Pharmacological
psychotropic
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Intervention_Pharmacological
3- ( 2-benzylmethylaminoethyl ) benzoic acid methyl ester hydrochloride ( PRL-8-53 )
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Intervention_Pharmacological
PRL-8-53
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Intervention_Control
placebo
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Outcome_Mental
learning
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Outcome_Mental
retention
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Outcome_Mental
learning
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Outcome_Mental
retention of verbal information
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Outcome_Mental
acquisition . Retinetion of verbal information
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Outcome_Mental
visual reaction time or motor control