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document
Irrigation with bupivacaine at the surgical bed for postoperative pain relief after laparoscopic cholecystectomy . PURPOSE The aim of this study was to evaluate the effect of bupivacaine irrigated at the surgical bed on postoperative pain relief in laparoscopic cholecystectomy patients . METHODS This study included 60 patients undergoing elective laparoscopic cholecystectomy who were prospectively randomized into 2 groups . The placebo group ( n=30 ) received 20cc saline without bupivacaine , installed into the gallbladder bed . The bupivacaine group ( n=30 ) received 20cc of 0.5 % bupivacaine in at the same surgical site . Pain was assessed at 0 , 6 , 12 , and 24 hours by using a visual analog scale ( VAS ) . RESULTS A significant difference ( P=.018 ) was observed in pain levels between both groups at 6 hours postoperatively . The average analgesic requirement was lower in the bupivacaine group , but this did not reach statistical significance . CONCLUSIONS In our study , the use of bupivacaine irrigated over the surgical bed was an effective method for reducing pain during the first postoperative hours after laparoscopic cholecystectomy .
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Intervention_Pharmacological
bupivacaine
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Intervention_Pharmacological
bupivacaine
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Intervention_Control
placebo
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Intervention_Control
saline without bupivacaine
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Intervention_Pharmacological
bupivacaine
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Intervention_Pharmacological
bupivacaine
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Intervention_Pharmacological
bupivacaine
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Intervention_Pharmacological
bupivacaine
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Outcome_Pain
postoperative pain relief
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Outcome_Other
effect
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Outcome_Pain
postoperative pain relief
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Outcome_Pain
Pain
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Outcome_Pain
pain levels
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Outcome_Physical
average analgesic requirement
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Outcome_Pain
pain
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Participant_Condition
postoperative pain
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Participant_Condition
laparoscopic cholecystectomy
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Participant_Condition
laparoscopic cholecystectomy
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Participant_Sample-size
60
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Participant_Condition
laparoscopic cholecystectomy