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document
Mode of ventilation during cardiopulmonary bypass does not affect immediate postbypass oxygenation in pediatric cardiac patients . STUDY OBJECTIVE To investigate the impact of different modes of ventilation during cardiopulmonary bypass ( CPB ) on immediate postbypass oxygenation in pediatric cardiac surgery . DESIGN Prospective , randomized clinical trial . SETTING University hospital . PATIENTS 50 pediatric patients ( 18 girls , 32 boys ) , aged 4 months to 15 years , undergoing elective repair of congenital heart disease . INTERVENTIONS Patients were randomized to receive one of 5 modes of ventilation during bypass . Groups 1 and 2 received high-frequency/low-volume ventilation with 100 % ( group 1 ) or 21 % oxygen ( group 2 ) . Groups 3 and 4 received continuous positive airway pressure of 5 cm H ( 2 ) O with 100 % ( group 3 ) or 21 % oxygen ( group 4 ) ; and in group 5 , each patient 's airway was disconnected from the ventilator ( passive deflation ) . MEASUREMENTS Blood gas analysis and spirometry data were recorded 5 minutes before chest opening , 5 minutes before inducing bypass , 5 minutes after weaning from bypass , and 5 minutes after chest closure . MAIN RESULTS There were no differences in Pao ( 2 ) values among the 5 groups studied and at the different time points . Lung compliance was higher 5 minutes before bypass in group 1 versus group 5 ( 34 +/- 13 mL/cm H ( 2 ) O vs 20 +/- 9 mL/cm H ( 2 ) O ; P = 0.048 ) . CONCLUSIONS Mode of ventilation during CPB did not affect immediate postbypass oxygenation .
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Intervention_Physical
Mode of ventilation during
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Intervention_Surgical
cardiopulmonary bypass
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Intervention_Physical
modes of ventilation during
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Intervention_Surgical
cardiopulmonary bypass ( CPB )
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Intervention_Physical
one of 5 modes of ventilation during
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Intervention_Surgical
bypass
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Intervention_Surgical
high-frequency/low-volume ventilation with 100 %
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Intervention_Surgical
continuous positive airway pressure of 5 cm H ( 2 ) O with 100 %
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Intervention_Other
21 % oxygen
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Intervention_Surgical
each patient 's airway was disconnected from the ventilator ( passive deflation )
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Intervention_Physical
Mode of
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Intervention_Surgical
ventilation
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Outcome_Other
Blood gas analysis and spirometry data
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Outcome_Physical
Pao ( 2 ) values
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Outcome_Physical
Lung compliance
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Participant_Condition
pediatric cardiac patients .