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document
Comparison of endotracheal and peripheral intravenous adrenaline in cardiac arrest . Is the endotracheal route reliable ? Twelve patients presenting to an accident and emergency department in asystolic cardiac arrest were randomly allocated to treatment with endotracheal adrenaline ( five patients ) or peripheral intravenous adrenaline ( seven patients ) . Femoral-artery blood samples were taken for assay of adrenaline and noradrenaline . After intravenous adrenaline there was a good clinical and biochemical response , but after endotracheal adrenaline there was no change in serum adrenaline and no measurable clinical response . The endotracheal route of adrenaline administration is not reliable in out-of-hospital cardiac arrest .
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Intervention_Pharmacological
endotracheal and peripheral intravenous adrenaline
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Intervention_Pharmacological
endotracheal adrenaline
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Intervention_Pharmacological
peripheral intravenous adrenaline
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Intervention_Pharmacological
adrenaline
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Intervention_Pharmacological
noradrenaline
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Intervention_Pharmacological
adrenaline
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Intervention_Pharmacological
adrenaline
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Outcome_Physical
clinical and biochemical response
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Outcome_Physical
no change in serum adrenaline
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Outcome_Physical
measurable clinical response
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Participant_Condition
cardiac arrest .
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Participant_Sample-size
Twelve