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document
Randomised controlled trial of patient triggered and conventional fast rate ventilation in neonatal respiratory distress syndrome . AIM To compare patient triggered , with conventional fast rate , ventilation in a randomised controlled trial using the incidence of chronic lung disease as the primary outcome measure . METHODS Three hundred and eighty six preterm infants with birthweights from 1000 to 2000 g , and requiring ventilation for respiratory distress syndrome within 24 hours of birth , were randomised to receive either conventional or trigger ventilation with the SLE 2000 ventilator . RESULTS There were no significant differences in the incidence of chronic lung disease ( 28 day and 36 week definitions ) , death , pneumothorax , intraventricular haemorrhage , number of ventilator days , or length of oxygen dependency between groups . CONCLUSIONS Patient triggered ventilation in preterm infants with respiratory distress syndrome is feasible . No significant differences , when compared with conventional fast rate ventilation in important medium and longer term outcome measures , were evident .
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Intervention_Physical
conventional fast rate ventilation
2400
Intervention_Pharmacological
trigger ventilation
2401
Outcome_Physical
incidence of chronic lung disease
2402
Outcome_Physical
incidence of chronic lung disease
2403
Outcome_Mortality
death
2404
Outcome_Physical
pneumothorax , intraventricular haemorrhage
2405
Outcome_Other
number of ventilator days , or length of oxygen dependency
2406
Participant_Condition
neonatal respiratory distress syndrome .