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document
Use of Interceed ( TC7 ) absorbable adhesion barrier to reduce postoperative adhesion reformation in infertility and endometriosis surgery . The Obstetrics and Gynecology Adhesion Prevention Committee . Interceed ( TC7 ) is a fabric composed of oxidized , regenerated cellulose that was designed to reduce the formation of postsurgical adhesions . We evaluated Interceed ( TC7 ) in a randomized , multicenter clinical study . Sixty-three infertility patients had bilateral pelvic sidewall adhesions removed at laparotomy . One pelvic sidewall was covered by Interceed ( TC7 ) and the other was left uncovered . The deperitonealized areas ( N = 205 ) of all sidewalls were divided into three groups : less than 100 mm2 , N = 72 ; 100-1000 mm2 , N = 95 ; and more than 1000 mm2 , N = 38 . The effectiveness of Interceed ( TC7 ) was evaluated at laparoscopy 10-98 days after laparotomy . Significantly more adhesions were observed at laparoscopy on the control pelvic sidewalls ( 48 of 63 , 76 % ) than on the treated sides ( 26 of 63 , 41 % ) ( P less than .0001 ) . The Interceed ( TC7 ) -treated sidewalls also had significantly less area involved with adhesions at laparoscopy ( P less than .05 , P less than .001 , and P less than .001 in the three groups , respectively ) . Twenty-eight women with severe endometriosis also had significantly more adhesions on the control side ( 23 of 28 , 82 % ) than on the treated side ( 14 of 28 , 50 % ) ( P less than .05 ) . We conclude that Interceed ( TC7 ) effectively reduced the incidence and extent of postoperative adhesions , even in patients with severe endometriosis .
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Intervention_Physical
Interceed ( TC7 ) absorbable adhesion barrier
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Intervention_Physical
Interceed ( TC7 )
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Intervention_Physical
Interceed ( TC7
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Intervention_Pharmacological
)
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Intervention_Physical
Interceed ( TC7 )
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Intervention_Educational
other was left uncovered
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Intervention_Physical
Interceed ( TC7 )
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Intervention_Physical
laparotomy
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Intervention_Pharmacological
Interceed ( TC7 )
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Intervention_Pharmacological
Interceed ( TC7 )
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Outcome_Physical
postoperative adhesion reformation
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Outcome_Physical
effectiveness of Interceed ( TC7 )
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Outcome_Physical
adhesions
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Outcome_Physical
area involved with adhesions
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Outcome_Physical
adhesions
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Outcome_Physical
postoperative adhesions
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Participant_Condition
infertility
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Participant_Condition
endometriosis
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Participant_Sample-size
Sixty-three
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Participant_Condition
infertility