9251
document
Effectiveness of a brief cognitive-behavioural therapy intervention in the treatment of schizophrenia . BACKGROUND Little evidence exists to indicate whether community psychiatric nurses can achieve the results reported by expert cognitive-behavioural therapists in patients with schizophrenia . AIMS To assess the effectiveness and safety of a brief cognitive-behavioural therapy ( CBT ) intervention in a representative community sample of patients with schizophrenia in secondary care settings . METHOD A pragmatic randomised trial was performed involving 422 patients and carers to compare a brief CBT intervention against treatment as usual . RESULTS Patients who received CBT ( n=257 ) improved in overall symptomatology ( P=0.015 ; number needed to treat [ NNT ] =13 ) , insight ( P < 0.001 ; NNT=10 ) and depression ( P=0.003 ; NNT=9 ) compared with the control group ( n=165 ) . Insight was clinically significantly improved ( risk ratio=1.15 , 95 % CI 1.01-1.31 ) . There was no increase in suicidal ideation . CONCLUSIONS Community psychiatric nurses can safely and effectively deliver a brief CBT intervention to patients with schizophrenia and their carers .
9252
Intervention_Educational
cognitive-behavioural therapy intervention
9253
Intervention_Educational
cognitive-behavioural therapists
9254
Intervention_Educational
cognitive-behavioural therapy ( CBT ) intervention
9255
Intervention_Educational
CBT intervention
9256
Intervention_Educational
CBT ( n=257 )
9257
Intervention_Educational
CBT intervention
9258
Outcome_Mental
overall symptomatology
9259
Outcome_Other
number needed to treat
9260
Outcome_Mental
insight
9261
Outcome_Mental
depression
9262
Outcome_Physical
Insight
9263
Outcome_Mental
suicidal ideation
9264
Outcome_Other
safely
9265
Outcome_Other
effectively
9266
Participant_Condition
patients with schizophrenia
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Participant_Condition
schizophrenia
9268
Participant_Sample-size
422