32020
document
[ Effect of electroacununcture on sex hormone levels in patients with Sjögren 's syndrome ] . OBJECTIVE To observe the effect of electroacupuncture ( EA ) on serum testosterone ( T ) , estradiol ( F2 ) , luteotropic hormone ( LH ) , follicle-stimulating hormone ( FSH ) , progesterone ( P ) , and prolactin ( PRL ) in patients with Sjögren 's Syndrome ( SS ) in order to analyze the correlation between the adjustment effect of EA and changes of hormone levels . METHODS Fifty-seven middle-aged and old women with SS were divided into medication group ( n=27 ) and acupuncture group ( n=30 ) . Patients in acupuncture group were treated with EA ( 80 Hz , 2.5 mA ) of Shenshu ( BL 23 ) , Taixi ( KI 3 ) , Hegu ( LI 4 ) , etc . for 30 min , once every other day , and those of medication group were treated with oral administration of hydroxyl-chloroquine ( 6 mg/kg per day ) , oral transfer agent liquid , Vit B1 , Vit B2 , Vit C , fish-liver oil , one tablet/time , t.i.d. , and pilocarpine ( 20 mg/d ) , continuously for 2 months . Venous blood samples were collected before and after the treatment to examine contents of the abovementioned sex hormones by using electro-chemiluminescent immunoassay ( CLIA ) . RESULTS ( 1 ) Before the treatment , no significant differences were found between two groups in the levels of serum T , E2 , LH , FSH , P and PRL ( P > 0.05 ) . After the treatment , self-comparison of each group showed that serum EF and T contents in acupuncture group increased significantly ( P < 0.01 ) and serum LH content decreased significantly ( P < 0.01 ) ; while in medication group , only serum LH decreased markedly ( P < 0.05 ) in comparison with its basic value of pretreatment . No significant changes were found in serum P , FSH and PRL levels in both groups after the treatment ( P > 0.05 ) . The results suggested that the therapeutic effect of acupuncture group was better than that of medication group in regulating multiple sex hormones . CONCLUSION EA can effectively adjust E2 , T and LH levels in Sjögren 's Syndrome patients and improve most patients ' clinical symptoms , and the therapeutic effect of EA is better than that of medication .
32021
Intervention_Physical
electroacununcture
32022
Outcome_Physical
serum testosterone