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document
Sinemet CR in Parkinson 's disease . Sinemet CR , a controlled release carbidopa/levodopa preparation , was compared to conventional carbidopa/levodopa in a double blind , placebo-controlled trial . Comparable clinical benefits and adverse effects were noted with the two medications . However significantly less frequent dosing was necessary with Sinemet CR .
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Intervention_Pharmacological
Sinemet CR
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Intervention_Pharmacological
Sinemet CR
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Intervention_Pharmacological
carbidopa/levodopa preparation
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Intervention_Pharmacological
carbidopa/levodopa
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Intervention_Control
placebo-controlled
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Outcome_Other
clinical benefits
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Outcome_Adverse-effects
adverse effects
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Participant_Condition
Sinemet CR in Parkinson 's disease .