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document
New mini-extracorporeal circulation system ( ECC.O ) is a safe technique in coronary surgery . OBJECTIVES Cardiopulmonary bypass ( CPB ) is known to cause the systemic inflammatory reaction after cardiac surgery . New coated and closed loop circuit systems may reduce this inflammation response and improve the surgical outcome . This study was designed to evaluate the safety and efficacy of the mini-extracorporeal circulation system ( ECC.O ) in CABG patients . DESIGN Forty patients undergoing elective coronary surgery were randomized into two groups , the ECC.O group and the standard CPB group . Routine hemodynamic monitoring and biochemical measurements were registered according to the hospital practice . RESULTS The clinical outcome of the patients was similar in both groups . There were no significant differences between the groups in the duration of intubation following surgery , the length of intensive care unit-stay or the total hospital stay . The haemoglobin level was significantly higher ( p=0.0069 ) during and after the perfusion in the ECC.O group . CONCLUSIONS The ECC.O system can be safely used in CABG patients and it maintains haemoglobin level better than conventional CPB .
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Intervention_Surgical
New mini-extracorporeal circulation system ( ECC.O )
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Intervention_Surgical
Cardiopulmonary bypass ( CPB )
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Intervention_Surgical
mini-extracorporeal circulation system ( ECC.O )
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Intervention_Physical
ECC.O group and the
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Intervention_Control
standard CPB group
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Intervention_Physical
ECC.O
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Intervention_Physical
ECC.O
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Intervention_Surgical
CPB
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Outcome_Physical
inflammation response
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Outcome_Physical
improve the surgical outcome
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Outcome_Other
duration of intubation following surgery
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Outcome_Other
length of intensive care unit-stay
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Outcome_Other
total hospital stay
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Outcome_Physical
haemoglobin level
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Participant_Condition
CABG patients
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Participant_Sample-size
Forty patients
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Participant_Condition
elective coronary surgery
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Participant_Condition
CABG patients