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document
Effect of reduced alcohol consumption on blood pressure in untreated hypertensive men . Fifty-four untreated , mildly hypertensive men whose daily alcohol consumption was > or = 28 ml ethanol and who drank at least 4 times per week took part in a randomized , controlled crossover trial . The purpose of the trial was to test the effects of alcohol reduction on blood pressure . After a 2-week familiarization period , the participants were assigned to either a reduced alcohol drinking group or a usual drinking group for 3 weeks ( experimental period 1 ) . The situation was then reversed for the next 3 weeks ( experimental period 2 ) . The participants were requested to limit their daily alcohol consumption to zero or reduce it as much as possible for the reduced alcohol consumption period . The self-reported alcohol consumption was 56.1 +/- 3.6 ( SEM ) ml/day during the usual alcohol drinking period and 26.1 +/- 3.0 ml/day during the period of reduced alcohol consumption . Systolic and diastolic blood pressures in the intervention group were found by analysis of variance to be significantly lower ( 2.6-4.8 and 2.2-3.0 mm Hg , respectively ) than those in the control group during experimental period 2 for systolic blood pressure and experimental period 1 for diastolic blood pressure . Significant ( 3.6 mm Hg ) and nonsignificant ( 1.9 mm Hg ) decreases in systolic and diastolic blood pressure , respectively , were observed . The method of Hills and Armitage was used , reducing ethanol in daily alcohol consumption by 28 ml . The lowering effect of reduced alcohol consumption on blood pressure was independent of changes in salt consumption , which were estimated by 24-hour urine collection and body weight . ( ABSTRACT TRUNCATED AT 250 WORDS )
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Intervention_Educational
reduced alcohol drinking
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Intervention_Control
usual drinking group
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Intervention_Educational
limit their daily alcohol consumption to zero
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Intervention_Educational
reduce it as much as possible for the reduced alcohol consumption period
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Outcome_Other
Effect
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Outcome_Physical
blood pressure
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Outcome_Other
effects
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Outcome_Physical
blood pressure .
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Outcome_Physical
self-reported alcohol consumption
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Outcome_Physical
Systolic and diastolic blood pressures
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Outcome_Physical
systolic blood pressure
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Outcome_Physical
diastolic blood pressure .
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Outcome_Physical
systolic and diastolic blood pressure
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Participant_Condition
hypertensive
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Participant_Sex
men
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Participant_Sample-size
Fifty-four