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document
[ Tocolysis with hexoprenalin and salbutamol in a clinical comparison ] . 140 patients with a threatening premature birth at the greater than or equal to 24-less than 37 week of gestation were in this study randomly treated with hexoprenalin or salbutamol . In 77 % in the hexoprenalin and in 74 % in the salbutamol group the weight of the newborn was greater than or equal to 2500 g. In 66 % in both study groups the birth occurred after the completed 37 weeks of gestation . During infusion of hexoprenalin tachycardia in mothers occurred statistically highly significantly less than during salbutamol . 11 % of the mothers in the hexoprenalin group had side-effects during infusion compared to 30 % in the salbutamol group . The correlation between the tocolysis-index ( Baumgarten ) and the prolongation-index ( Richter ) given by the regression lines facilitates in some measure the comparison of different tocolytic drugs concerning its tocolytic effect .
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Intervention_Pharmacological
hexoprenalin
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Intervention_Pharmacological
salbutamol
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Intervention_Pharmacological
hexoprenalin
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Intervention_Pharmacological
salbutamol
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Intervention_Pharmacological
hexoprenalin
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Intervention_Pharmacological
salbutamol
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Intervention_Pharmacological
hexoprenalin
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Intervention_Pharmacological
salbutamol
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Intervention_Pharmacological
hexoprenalin
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Intervention_Pharmacological
salbutamol
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Outcome_Physical
weight of the newborn
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Outcome_Physical
weeks of gestation .
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Outcome_Physical
tachycardia
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Outcome_Adverse-effects
side-effects during infusion
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Outcome_Physical
tocolysis-index ( Baumgarten )
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Outcome_Physical
prolongation-index ( Richter )
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Participant_Condition
140 patients with a threatening premature birth at the greater than or equal to 24-less than 37 week of gestation