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document
Gastric contents and pH after oral premedication . Forty women , aged 26-40 years , were investigated with regard to gastric contents and pH before general anaesthesia . The patients were divided into two groups ( 20 in each ) . Group 100 received 0.3 mg kg-1 diazepam orally with 100 ml of water 2 h before surgery . Group 50 received 0.3 mg kg-1 diazepam with 50 ml of water 2 h before surgery . The amount of gastric content was significantly greater in Group 100 than in Group 50 ( P less than 0.05 ) . There was no statistical difference in pH values between the groups . The number of patients with both gastric pH less than 2.5 and gastric volume greater than 25 ml was significantly higher in Group 100 compared to Group 50 ( P less than 0.05 ) . We can not recommend the use of oral premedication using these amounts of water , considering the increased risk of aspiration of gastric contents .
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Intervention_Physical
premedication
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Intervention_Physical
anaesthesia
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Intervention_Pharmacological
diazepam
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Intervention_Pharmacological
water
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Intervention_Pharmacological
diazepam with
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Intervention_Pharmacological
water
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Intervention_Pharmacological
premedication
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Outcome_Physical
Gastric contents
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Outcome_Physical
amount of gastric content
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Outcome_Physical
pH values
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Outcome_Physical
gastric pH
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Outcome_Physical
gastric volume
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Participant_Age
Forty women , aged 26-40 years