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document
Anaerobic infection in cancer patients : comparative evaluation of clindamycin and cefoxitin . Clindamycin and cefoxitin with or without gentamicin were administered to cancer patients having localized infections presumably caused by anaerobic pathogens . The rates of favorable response were 89 % in patients receiving clindamycine alone and 78 % in patients receiving cefoxitin alone . When the total experience is considered ( clindamycin or cefoxitin with and without gentamicin ) , 20 of 24 patients ( 83 % ) responded to clindamycin and 18 of 22 ( 82 % ) responded to cefoxitin . Both therapies were well tolerated . Clindamycin was found to be more effective than cefoxitin in eradicating the offending anaerobic pathogens from the site of infection . Aerobic pathogens were frequently isolated along with anaerobes from the infectious sites in this series ; their susceptibility or resistance to clindamycin or cefoxitin did not influence the therapeutic response .
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Intervention_Pharmacological
clindamycin
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Intervention_Pharmacological
cefoxitin . Clindamycin and cefoxitin with or without gentamicin
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Intervention_Pharmacological
clindamycine alone
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Intervention_Pharmacological
cefoxitin alone .
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Intervention_Pharmacological
( clindamycin
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Intervention_Pharmacological
cefoxitin with and without gentamicin )
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Intervention_Pharmacological
clindamycin
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Intervention_Pharmacological
cefoxitin .
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Intervention_Pharmacological
Clindamycin
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Intervention_Pharmacological
clindamycin
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Intervention_Pharmacological
cefoxitin
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Outcome_Other
favorable response
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Outcome_Other
responded
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Outcome_Other
responded
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Outcome_Other
tolerated
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Outcome_Other
effective
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Outcome_Physical
eradicating the offending anaerobic pathogens from the site of infection
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Participant_Condition
Anaerobic infection in cancer patients
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Participant_Condition
cancer patients having localized infections presumably caused by anaerobic pathogens
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Participant_Sample-size
20 of 24
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Participant_Sample-size
18 of 22