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document
Use of topical selamectin for the treatment of Syphacia muris infection in laboratory rats . Efficacy of selamectin was studied in naturally acquired S. muris infections in rats . Fourty-eight S. muris-positive rats were divided into six treated and two control groups . Selamectin ( 6 mg/kg ) was applied topically to the skin in a single spot at the base of the neck in the treatment group . The rats of treated and control groups were necropsied on the 24th day after the treatment . Topical selamectin was found to be 40.7-63.3 % effective ( based on egg per gram method ) in eliminating S. muris infection in rats . The efficacy of the treatment against S. muris ( based on adult worm counts ) in male and female rats was 35.14-58.88 % , respectively ( mean 48.39 % ) .
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Intervention_Pharmacological
selamectin
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Intervention_Pharmacological
selamectin
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Intervention_Pharmacological
Selamectin
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Intervention_Pharmacological
selamectin
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Outcome_Other
Efficacy
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Outcome_Other
effective ( based on egg per gram method ) in eliminating S.
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Outcome_Physical
muris infection
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Outcome_Other
efficacy of the treatment
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Participant_Sample-size
Fourty-eight
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Participant_Condition
S. muris-positive rats
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Participant_Sex
male and female rats