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document
Comparison of the therapeutic efficacy of phonophoresis and iontophoresis using dexamethasone sodium phosphate in the management of patients with knee osteoarthritis . BACKGROUND AND OBJECTIVE Many treatment options , including non-pharmacological and pharmacological measures , have been recommended in the management of osteoarthritis ( OA ) . Among the non-pharmacological approach is physiotherapy , which involves the use of physical modalities like , heat therapy , exercise therapy , electrical stimulation , therapeutic ultrasound , iontophoresis , and phonophoresis . This study was therefore designed to compare the effectiveness of 0.4 % Dexamethasone sodium phosphate ( DEX-P ) phonophoresis ( PH ) with 0.4 % DEX-P iontophoresis ( ION ) therapy in the management of patients with knee joint OA . METHODS Fifty patients ( 19 males and 31 females ) with a mean age of 53.6 +/- 8.9 years were randomly assigned to PH or ION groups with 25 patients in each group . Ultrasound waves of 1 MHz frequency was applied for 5 minutes to the target knee , so also was the direct current for 10 minutes for 10 sessions treatment period . Western Ontario and McMaster University Osteoarthritis Index ( WOMAC ) scores , 20 meters ambulatory time , and knee range of motion ( ROM ) were evaluated before and after therapy as the outcome measures . RESULTS At the end of two weeks , significant improvement in total WOMAC scores was observed in 15 ( 60 % ) and 16 ( 64 % ) patients in the PH and ION groups respectively , indicating no significant difference in the improvement rate . Twenty ( 20 ) metres ambulatory time and knee range of motion also improved significantly in both groups , yet these variables showed no significant difference between the two groups . CONCLUSION Both therapeutic modalities were found to be effective and generally well tolerated after 10 treatment sessions . DEX-P phonophoresis was not superior to DEX-P iontophoresis in the treatment of patients with OA of the knee .
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Intervention_Physical
phonophoresis
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Intervention_Physical
iontophoresis
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Intervention_Pharmacological
dexamethasone sodium phosphate
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Intervention_Pharmacological
Dexamethasone sodium phosphate ( DEX-P )
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Intervention_Physical
phonophoresis ( PH )
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Intervention_Pharmacological
0.4 % DEX-P
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Intervention_Physical
iontophoresis ( ION ) therapy
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Intervention_Physical
PH
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Intervention_Physical
ION
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Intervention_Pharmacological
DEX-P
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Intervention_Physical
phonophoresis
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Intervention_Pharmacological
DEX-P
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Intervention_Physical
iontophoresis
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Outcome_Physical
Western Ontario and McMaster University Osteoarthritis Index ( WOMAC ) scores
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Outcome_Physical
20 meters ambulatory time
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Outcome_Physical
knee range of motion ( ROM )
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Outcome_Physical
WOMAC scores
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Outcome_Physical
ambulatory time
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Outcome_Physical
knee range of motion
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Participant_Condition
patients with knee osteoarthritis .
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Participant_Condition
patients with OA of the knee .