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document
[ Assessment of natriuretic peptide indices and oxidative stress in patients with chronic heart failure ] . The authors have studied indices of natriuretic peptide and oxidative stress in patients with chronic heart failure ( CHF ) . 52 male patients with postinfarction cardiosclerosis ( PICS ) who have developed CHF have been observed . The age of the patients varied from 38 till 60 . It was established that CHF patients with progression of the disease had worsening of their clinical condition together with an increase of oxidative stress which was characterized through decrease of NO metabolites , NADPH -- diaphorase ( eNOS ) , increase of nitrite reductase ( iNOS ) and peroxinitrite ( ONOO ) , correlative increase the level of brain natriuretic peptide in blood plazma . Reliable connection between considerable increase of oxidative stress and the level of NT-pro BNP was noted in CHF patients , which demands necessity of correction of observed disorders .
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Intervention_Pharmacological
natriuretic peptide
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Intervention_Educational
oxidative
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Intervention_Pharmacological
natriuretic peptide
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Intervention_Educational
52 male
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Intervention_Physical
patients with postinfarction cardiosclerosis ( PICS ) who have developed CHF have been observed
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Outcome_Physical
clinical condition
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Outcome_Physical
oxidative stress
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Outcome_Physical
NO metabolites
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Outcome_Physical
NADPH -- diaphorase ( eNOS )
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Outcome_Physical
nitrite reductase ( iNOS )
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Outcome_Physical
peroxinitrite ( ONOO )
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Outcome_Physical
brain natriuretic peptide in blood plazma
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Outcome_Physical
oxidative stress
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Outcome_Physical
level of NT-pro BNP
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Participant_Condition
chronic heart failure
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Participant_Condition
chronic heart failure ( CHF )
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Participant_Sample-size
52
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Participant_Sex
male
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Participant_Condition
CHF
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Participant_Age
38 till 60
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Participant_Condition
CHF