33411
document
Effect of a dental cream containing amorphous cream phosphate complexes on white spot lesion regression assessed by laser fluorescence . PURPOSE To investigate and compare the effects of a dental cream containing complexes of casein phosphoprotein-amorphous calcium phosphate ( CPP-ACP ) and fluoride mouthwashes on the regression of white spot lesions ( WSL ) . MATERIALS AND METHODS The study group consisted of 26 healthy adolescents ( mean age 14.6 years ) exhibiting 60 teeth with 152 visible WSL sites on incisors and canines immediately after debonding of fixed orthodontic appliances . After bracket removal , professional tooth cleaning and drying , a visual scoring ( 0-4 ) and laser fluorescence ( LF ) readings were carried out . The patients were randomly assigned to two different treatment protocols with the aim of remineralising the lesions : A ) daily topical applications of a dental cream containing CPP-ACP ( Topacal ) for 3 months followed by a 3-month period of daily toothbrushing with fluoridated dentifrice , or B ) daily 0.05 % sodium fluoride mouthwash combined with fluoridated dentifrice for 6 months . The registrations were repeated after 1 , 3 , 6 and 12 months and follow-up data were compared with baseline with aid of chi-square and paired t-tests . RESULTS A significant improvement of the clinical WSL-scores was found over time in both groups , but there was a statistically significant difference ( p < 0.01 ) concerning the number of sites that totally disappeared after 12 months in favour of the CPP-ACP regime , 63 % compared with 25 % respectively . The clinical registrations were mirrored by a statistically significant decrease ( p < 0.05 ) in the LF readings at the 6- and 12-month follow-ups compared with baseline . No significant differences were displayed between the groups . CONCLUSIONS Clinical scoring and LF assessment suggested that both regimens could promote regression of WSL after debonding of fixed orthodontic appliances . The visual evaluation suggested an aesthetically more favourable outcome of the amorphous calcium phosphate treatments .
33412
Intervention_Pharmacological
amorphous cream phosphate complexes
33413
Intervention_Pharmacological
casein phosphoprotein-amorphous calcium phosphate
33414
Intervention_Pharmacological
fluoride
33415
Intervention_Surgical
bracket removal
33416
Intervention_Physical
professional tooth cleaning and drying
33417
Intervention_Physical
a visual scoring ( 0-4 ) and laser fluorescence ( LF ) readings
33418
Intervention_Pharmacological
daily topical applications of a dental cream containing CPP-ACP ( Topacal ) for 3 months
33419
Intervention_Physical
followed by a 3-month period of daily toothbrushing with fluoridated dentifrice , or B )
33420
Intervention_Control
daily 0.05 % sodium fluoride mouthwash combined with fluoridated dentifrice for 6 months
33421
Intervention_Pharmacological
amorphous calcium phosphate treatments
33422
Outcome_Physical
clinical WSL-scores
33423
Outcome_Other
number of sites that totally disappeared
33424
Outcome_Physical
LF readings