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A randomized pilot study with daily walking during adjuvant chemotherapy for patients with breast and colorectal cancer . BACKGROUND Physical activity during chemotherapy has been shown in several studies to reduce fatigue , improve symptoms and impact positively on health-related quality of life ( HRQoL ) . Challenges associated with intervention studies on physical activity during cancer treatment relate to consistent adherence . The primary objective was to study feasibility and adherence of physical activity intervention among patients with cancer during adjuvant chemotherapy treatment . The secondary objective was to investigate the effects of physical activity on health aspects , including HRQoL , symptoms and surrogate markers for cardiovascular disease . MATERIAL AND METHODS This randomized controlled trial included patients with breast cancer ( BRCA ) and colorectal cancer ( CRC ) during adjuvant chemotherapy . The intervention continued for 10 weeks and included daily walks of 10 000 steps and a weekly supervised group walk . Adherence was assessed by a pedometer and the number of participants who reported step counts every week and percentage of participants who achieved the target steps every week . RESULTS Adherence average reached 91 % during the intervention period ; in total 74 % completed the exercise intervention . The majority of the participants achieved an average of 83 % of the target of 10 000 steps per day for 10 weeks . There was a significant increase in daily physical activity ( p = 0.016 ) in the intervention group . Significant differences were also found for some breast cancer-specific symptoms [ swelling , mobility and pain ( p = 0.045 ) ] . The study showed a relatively small weight gain an average of 0.9 kg in the intervention group and 1.3 kg in the control group . CONCLUSION Physical activity in the form of walking is feasible during adjuvant chemotherapy treatment despite increasing symptoms . The physical activity increased in the intervention group during the study time and had a positive impact on breast symptoms and the weight gain was lower in comparison to previous studies .
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Intervention_Physical
daily walking
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Intervention_Physical
Physical activity
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Intervention_Physical
physical activity
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Intervention_Physical
physical activity intervention
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Intervention_Physical
physical activity
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Intervention_Pharmacological
adjuvant chemotherapy
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Intervention_Physical
daily walks
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Intervention_Physical
exercise
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Intervention_Physical
daily physical activity
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Intervention_Control
control group
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Intervention_Physical
Physical activity
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Intervention_Physical
physical activity
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Outcome_Physical
fatigue , improve symptoms and impact positively on health-related quality of life ( HRQoL ) .
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Outcome_Physical
health aspects
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Outcome_Physical
HRQoL , symptoms and surrogate markers for cardiovascular disease .
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Outcome_Physical
Adherence
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Outcome_Physical
Adherence
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Outcome_Physical
daily physical activity
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Outcome_Physical
[ swelling
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Outcome_Physical
mobility
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Outcome_Pain
pain
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Outcome_Physical
small weight gain
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Outcome_Physical
breast symptoms
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Outcome_Physical
weight gain
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Participant_Condition
patients with breast and colorectal cancer .
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Participant_Condition
patients with cancer during adjuvant chemotherapy treatment .
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Participant_Condition
patients with breast cancer ( BRCA ) and colorectal cancer ( CRC ) during adjuvant chemotherapy .