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Clinical Study to Assess the Stain Removal Effectiveness of a Tooth Whitening Regimen with Added Whitening Booster . OBJECTIVE This randomized , controlled clinical trial was conducted to assess the extrinsic stain reduction achieved by brushing with a whitening dentifrice and powered toothbrush , and to determine whether the addition of a whitening booster paste to this regimen would enhance its stain reducing effectiveness . METHODS Sixty qualifying subjects were randomly assigned either to Regimen One , a whitening dentifrice ( Arm & Hammer Truly Radiant [ TR ] toothpaste ] and powered toothbrush ( Arm & Hammer Truly Radiant [ TR ] Extra Whitening Spinbrush ) ; Regimen Two , the dentifrice and powered toothbrush with the addition of a whitening booster ; or Regimen Three , a negative control ( Colgate Cavity Protection toothpaste and an ADA standard manual brush ) . They were instructed in the use of their assigned products and then brushed unsupervised at home for two minutes , twice daily , for 14 days . Extrinsic tooth stain was assessed at baseline and after two , five , and 14 days using a Modified Lobene Stain Index ( MLSI ) with Lobene inclusion criteria of ≥ 1.5 . RESULTS All three treatment groups had statistically significant ( p < 0.0001 ) mean total MLSI reductions from baseline at each time point , in a time-dependent manner . Day 14 reductions were 22.2 % for Colgate Cavity Protection , 29.1 % for Regimen One , and 34.4 % for Regimen Two . Reductions for Regimen One and Regimen Two were significantly greater compared to Regimen Three , the negative control , at each time period ( p < 0.01 ) , and those for Regimen Two were significantly greater compared to Regimen One on days 2 and 14 ( p < 0.05 ) and directionally more effective on day 5 ( p = 0.0673 ) . CONCLUSION The combination of Truly Radiant toothpaste and Truly Radiant Spinbrush provides safe and effective stain removal that can be further enhanced by the addition of the whitening booster .
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Intervention_Pharmacological
Tooth Whitening Regimen with Added Whitening Booster .
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Intervention_Pharmacological
a whitening dentifrice
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Intervention_Physical
powered toothbrush
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Intervention_Pharmacological
the dentifrice
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Intervention_Physical
and powered toothbrush with the addition of a
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Intervention_Pharmacological
whitening booster ;
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Intervention_Physical
negative control (
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Intervention_Pharmacological
Colgate Cavity Protection toothpaste
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Intervention_Physical
and an ADA standard manual brush )
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Outcome_Physical
extrinsic stain reduction
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Outcome_Other
stain reducing effectiveness
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Outcome_Physical
Extrinsic tooth
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Outcome_Physical
Modified Lobene Stain Index ( MLSI )
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Outcome_Other
0.0001 ) mean total MLSI reductions
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Outcome_Other
Two
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Outcome_Other
Reductions
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Outcome_Other
provides safe and effective stain removal
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Participant_Sample-size
Sixty qualifying subjects