75872
document
Nebulized racemic epinephrine by IPPB for the treatment of croup : a double-blind study . Racemic epinephrine has been advocated for the treatment of croup , but controlled studies have not proved it more effective than saline . Twenty patients ( aged 4 months to 5 years ) hospitalized with acute croup and persistent inspiratory stridor at rest were randomly assigned to one of two treatment groups : saline or racemic epinephrine , both nebulized and delivered by intermittent positive pressure breathing . Clinical scores were significantly improved ( P less than .01 ) at ten and 30 minutes following the treatment with racemic epinephrine but not at 120 minutes . Racemic epinephrine was significantly more effective than saline at 10 ( P less than .01 ) and 30 minutes ( P less than .05 ) but not at 120 minutes after the treatment . We conclude that nebulized racemic epinephrine is effective treatment for the acute signs of croup .
75873
Intervention_Pharmacological
racemic epinephrine
75874
Intervention_Pharmacological
Racemic epinephrine
75875
Intervention_Pharmacological
saline or racemic epinephrine
75876
Intervention_Pharmacological
racemic epinephrine
75877
Intervention_Pharmacological
Racemic epinephrine
75878
Intervention_Pharmacological
racemic epinephrine
75879
Outcome_Physical
Clinical scores
75880
Outcome_Other
effective
75881
Participant_Condition
croup
75882
Participant_Sample-size
Twenty patients
75883
Participant_Age
aged 4 months to 5 years
75884
Participant_Condition
croup