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document
Effect of delayed cord clamping on iron stores in infants born to anemic mothers : a randomized controlled trial . OBJECTIVE To study the effects of cord clamping on iron stores of infants born to anemic mothers at 3 months of age . DESIGN Randomized controlled trial . SETTING Teaching hospital . METHODS Infants born to mothers with hemoglobin ( Hb ) < 100 g/L were randomized at delivery to either immediate cord clamping ( early group ) or cord clamping delayed till descent of placenta into vagina ( delayed group ) . The outcome measures were infant 's hemoglobin and serum ferritin 3 months after delivery . RESULTS There were 102 neonates randomized to early ( n = 43 ) or delayed cord clamping ( n = 59 ) . The groups were comparable for maternal age , parity , weight and supplemental iron intake , infant s birth weight , gestation and sex . The mean infant ferritin and Hb at 3 months were significantly higher in the delayed clamping group ( 118.4 microg/L and 99 g/L ) than in the early clamping group ( 73 microg/L and 88 g/L ) . The mean decrease in Hb ( g/L ) at 3 months adjusted for co-variates was significantly less in the delayed clamping group compared to the early clamping group ( -1.09 , 95 % CI-1.58 to -0.62 , p > 0.001 ) . The odds for anemia ( < 100 g/L ) at 3 months was 7.7 ( 95 % CI 1.84-34.9 ) times higher in the early compared to the delayed clamping group . CONCLUSION Iron stores and Hb in infancy can be improved in neonates born to anemic mothers by delaying cord clamping at birth .
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Intervention_Surgical
delayed cord clamping
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Intervention_Surgical
immediate cord clamping
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Intervention_Surgical
cord clamping delayed till descent of placenta into vagina
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Intervention_Surgical
delayed clamping
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Intervention_Surgical
early clamping
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Intervention_Surgical
delayed clamping
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Intervention_Surgical
early clamping
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Intervention_Surgical
delayed clamping
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Intervention_Surgical
delaying cord clamping
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Outcome_Physical
iron stores
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Outcome_Physical
infant 's hemoglobin and serum ferritin 3 months after delivery
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Outcome_Physical
mean infant ferritin and Hb at 3 months
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Outcome_Physical
Hb
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Outcome_Physical
anemia
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Outcome_Physical
Iron stores
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Outcome_Physical
Hb
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Participant_Age
infants
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Participant_Condition
born to anemic mothers :