84517
document
Ketorolac versus fentanyl for gynaecological day-case surgery . The effectiveness of fentanyl and ketorolac in providing analgesia for day-case gynaecological procedures was evaluated in 55 healthy volunteers in a single blinded fashion . Fentanyl ( 1 mcg/kg iv ) and ketorolac ( 30 mg im ) were administered immediately following induction of anaesthesia . Anaesthesia was standardized with propofol , nitrous oxide and enflurane . Outcome variables assessed were pain , additional analgesic requirements , and incidence of postoperative nausea and vomiting . All variables were recorded at 15 minutes , 2 hours and 24 hours postoperatively . There was no significant difference between the 2 groups with respect to any of the measured variables . Both drugs were ineffective as sole analgesic agents in half of their respective groups . It may be that a combination of these drugs , providing a multireceptor approach to analgesia , will prove to be more effective .
84518
Intervention_Pharmacological
Ketorolac versus fentanyl
84519
Intervention_Pharmacological
fentanyl
84520
Intervention_Pharmacological
ketorolac
84521
Intervention_Pharmacological
Fentanyl
84522
Intervention_Pharmacological
ketorolac
84523
Intervention_Pharmacological
propofol
84524
Intervention_Pharmacological
nitrous oxide
84525
Intervention_Pharmacological
enflurane
84526
Outcome_Pain
pain
84527
Outcome_Pain
additional analgesic requirements
84528
Outcome_Adverse-effects
postoperative nausea and vomiting
84529
Outcome_Other
ineffective
84530
Outcome_Pain
analgesic
84531
Participant_Condition
gynaecological day-case surgery
84532
Participant_Condition
day-case gynaecological procedures
84533
Participant_Sample-size
55
84534
Participant_Condition
healthy volunteers