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document
The effects of chronic naltrexone treatment in young autistic children : a double-blind placebo-controlled crossover study . In a double-blind placebo-controlled crossover trial 23 autistic children , aged 3-7 years , were treated with a mean daily dosage of 1 mg/kg naltrexone for 4 weeks . Drug effects were monitored with behavior checklists rated by parents and teachers , and ethological playroom observations . On average , parents ' checklists and playroom data could not differentiate between naltrexone treatment and placebo treatment ; however , teachers significantly favored naltrexone treatment . They reported a decrease in hyperactivity and irritability . No effects of naltrexone on social and stereotypic behavior could be demonstrated .
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Intervention_Pharmacological
naltrexone
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Intervention_Pharmacological
naltrexone
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Intervention_Pharmacological
naltrexone
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Outcome_Mental
hyperactivity and irritability .
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Participant_Condition
young autistic
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Participant_Age
children
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Participant_Condition
:
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Participant_Condition
23 autistic
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Participant_Age
children
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Participant_Condition
, aged 3-7 years