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document
[ Comparison between anterior rhinomanometry and impulse-oscillometric rhinometry found within nasal allergen provocation ] . UNLABELLED Besides the standard method of anterior rhinomanometry ( aR ) , the impulse-oscillometric rhinometry ( IOS ) is available for measurements of the nasal resistance . The aR is a procedure dependent on the cooperation of the patient , whereas IOS is measured regardless from the breathing activities of the patient . We examined weather the resistance-measurement by means of IOS in comparison to the aR is a more suitable method for nasal allergic provocation . METHOD 17 patients with anamnestic known rhinokonjunktivitis ( 6 f , 11 m ) had a pricktest and then a nasal provocation testing with an allergen which provoked a reaction on the skin . The complete resistance of the nose was measured in a randomized order by means of aR and IOS . RESULTS The complete resistance showed neither in the basic measurement ( aR 0,38 +/- 0,14 kPa/l/s ; IOS 0,38 +/- 0,11 kPa/l/s ) nor in the control solution ( aR 0,38 +/- 0,14 ; IOS 0,39 +/- 0,14 ) nor after application of the allergenic solution ( 15 min : aR 0,69 +/- 0,27 ; IOS 0,77 +/- 0,42 ; 30 min : aR 0,65 +/- 0,29 ; IOS 0,6 +/- 0,38 ) a significant difference between the two methods . The results of the measurement of aR and IOS after the allergenic solution showed a positive correlation ( 15 min : r = 0,63 , p < 0,01 ; 30 min : r = 0,67 , p < 0,01 ) . We found by means of clinic and measurement methods in the aR of 7 patients a positive reaction , within 7 patient a negative reaction , 3 patients had a unspecific nasal hyperreactivity . There was a correspondence in 6 of the 7 patients with positive reaction in aR between both methods . 4 of the 7 results with negative reaction in the aR would have been positive then underlying the same criteria in the IOS without announcing the symptomscore a relevant clinical symptomatic while testing . CONCLUSION IOS is a suitable procedure for nasal provocation testing and provides results similar to the aR . In comparison to aR IOS is not dependent on the patients cooperation . Due to its higher sensitivity the valid limits of the aR at provocation testings can not be transferred to IOS to avoid a false positive reaction .
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Intervention_Physical
anterior rhinomanometry
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Intervention_Physical
impulse-oscillometric rhinometry
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Intervention_Physical
anterior rhinomanometry ( aR ) , the impulse-oscillometric rhinometry ( IOS )
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Intervention_Pharmacological
aR and IOS .
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Outcome_Physical
nasal allergen provocation
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Outcome_Physical
nasal resistance
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Outcome_Physical
nasal allergic provocation
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Outcome_Physical
resistance
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Outcome_Physical
complete resistance
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Outcome_Physical
measurement of aR and IOS
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Outcome_Physical
unspecific nasal hyperreactivity
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Outcome_Physical
symptomscore
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Outcome_Physical
false positive reaction
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Participant_Condition
nasal allergen
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Participant_Sample-size
17
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Participant_Condition
rhinokonjunktivitis
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Participant_Sample-size
7