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document
A randomized , prospective , parallel group study of laparoscopic versus laparoendoscopic single site donor nephrectomy for kidney donation . Few prospective , randomized studies have assessed the benefits of laparoendoscopic single site donor nephrectomy ( LESS-DN ) over laparoscopic donor nephrectomy ( LDN ) . Our center initiated such a trial in January 2011 , following subjects randomized to LESS-DN versus LDN from surgery through 5 years postdonation . Subjects complete recovery/satisfaction questionnaires at 2 , 6 and 12 months postdonation ; transplant recipient outcomes are also recorded . One hundred subjects ( 49 LESS-DN , 51 LDN ) underwent surgery ; donor demographics were similar between groups , and included a predominance of female , living-unrelated donors , mean age of 47 years who underwent left donor nephrectomy . Operative parameters ( overall time , time to extraction , warm ischemia time , blood loss ) were similar between groups . Conversion to hand-assist laparoscopy was required in 3 LESS-DN ( 6.1 % ) versus 2 LDN ( 3.9 % ; p = 0.67 ) . Questionnaires revealed that 97.2 % of LESS-DN versus 79.5 % of LDN ( p = 0.03 ) were 100 % recovered by 2 months after donation . No significant difference was seen in satisfaction scores between the groups . Recipient outcomes were similar between groups . Our randomized trial comparing LESS donor nephrectomy to LDN confirms that LESS-DN offers a safe alternative to conventional LDN in terms of intra- and post-operative complications . LDN and LESS-DN offer similar recovery and satisfaction after donation .
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Intervention_Surgical
laparoscopic
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Intervention_Physical
versus
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Intervention_Surgical
laparoendoscopic single site donor nephrectomy
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Intervention_Surgical
laparoendoscopic single site donor nephrectomy ( LESS-DN
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Intervention_Physical
)
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Intervention_Surgical
laparoscopic donor nephrectomy ( LDN
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Intervention_Physical
)
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Intervention_Surgical
LESS-DN
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Intervention_Physical
versus
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Intervention_Surgical
LDN
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Intervention_Surgical
LESS-DN
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Intervention_Surgical
LDN
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Intervention_Surgical
LESS-DN
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Intervention_Surgical
LDN
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Intervention_Surgical
LESS-DN
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Outcome_Other
benefits
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Outcome_Other
recovery/satisfaction questionnaires
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Outcome_Physical
overall time , time to extraction , warm ischemia time , blood loss
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Outcome_Physical
Conversion to hand-assist laparoscopy
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Outcome_Other
were 100 % recovered
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Outcome_Other
seen in satisfaction
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Outcome_Other
groups
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Outcome_Other
Recipient outcomes
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Outcome_Other
offers
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Outcome_Other
similar recovery and satisfaction
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Participant_Condition
nephrectomy for kidney donation .
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Participant_Sample-size
One hundred
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Participant_Age
47 years
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Participant_Condition
ischemia
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Participant_Condition
blood loss