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document
Exploring effects of different treadmill interventions on walking onset and gait patterns in infants with Down syndrome . Two cohorts of participants were included to investigate the effects of different treadmill interventions on walking onset and gait patterns in infants with Down syndrome ( DS ) . The first cohort included 30 infants with DS ( 17 males , 13 females ; mean age 10 mo [ SD 1.9 mo ] ) who were randomly assigned to either a lower-intensity-generalized ( LG ) training group , or a higher-intensity-individualized ( HI ) training group . A control ( C ) group from another study , who did not receive treadmill training , served as the control ( eight males , seven females ; mean age 10.4 mo [ SD 2.2 mo ] ) . Mean age at walking onset was 19.2 , 21.4 , and 23.9 months for the HI , LG , and C groups respectively . At walking onset the HI group was significantly younger than the C group ( p=0.011 ) . At the gait follow-up that was conducted between 1 and 3 months after walking onset , three groups significantly different in overall gait patterns ( p=0.037 ) were examined by six basic gait parameters including average velocity , stride length , step width , stride time , stance time , and dynamic base . Post-hoc analyses demonstrated that stride length was the gait parameter largely contributing to this overall group difference ( p=0.033 ) , and the HI group produced a significantly longer stride length than the C group ( p=0.030 ) . In conclusion , the HI treadmill intervention significantly promoted earlier walking onset and elicited more advanced gait patterns ( particularly in stride length ) in infants with DS .
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Intervention_Physical
treadmill interventions
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Intervention_Physical
treadmill interventions
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Intervention_Physical
lower-intensity-generalized ( LG ) training group
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Intervention_Physical
higher-intensity-individualized ( HI ) training group
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Intervention_Control
control ( C )
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Intervention_Physical
not receive treadmill training
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Outcome_Physical
walking onset
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Outcome_Physical
gait patterns
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Outcome_Physical
walking onset
33436
Outcome_Physical
gait patterns
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Outcome_Physical
Mean age at walking onset
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Outcome_Physical
walking onset
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Outcome_Physical
average velocity , stride length , step width , stride time , stance time , and dynamic base
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Outcome_Physical
stride length
33441
Outcome_Physical
stride length
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Outcome_Physical
walking onset
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Outcome_Physical
gait patterns
33444
Participant_Age
infants
33445
Participant_Condition
Down syndrome
33446
Participant_Age
infants
33447
Participant_Condition
Down syndrome
33448
Participant_Condition
DS
33449
Participant_Sample-size
30
33450
Participant_Age
infants
33451
Participant_Condition
DS
33452
Participant_Sample-size
17
33453
Participant_Sex
males
33454
Participant_Sample-size
13
33455
Participant_Sex
females
33456
Participant_Age
10 mo
33457
Participant_Condition
control ( C ) group
33458
Participant_Sample-size
eight
33459
Participant_Sex
males
33460
Participant_Sample-size
seven
33461
Participant_Sex
females
33462
Participant_Age
10.4 mo
33463
Participant_Age
infants
33464
Participant_Condition
DS