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Minimal clinically important change for pain intensity , functional status , and general health status in patients with nonspecific low back pain . STUDY DESIGN Cohort study . OBJECTIVES To estimate the Minimal Clinically Important Change ( MCIC ) of the pain intensity numerical rating scale ( PI-NRS ) , the Quebec Back Pain Disability Scale ( QBPDS ) , and the Euroqol ( EQ ) in patients with low back pain . SUMMARY OF BACKGROUND DATA MCIC can provide valuable information for researchers , healthcare providers , and policymakers . METHODS Data from a randomized controlled trial with 442 patients with low back pain were used . The MCIC was estimated over a 12-week period , and three different methods were used : 1 ) mean change scores , 2 ) minimal detectable change , and 3 ) optimal cutoff point in receiver operant curves . The global perceived effect scale ( GPE ) was used as an external criterion . The effect of initial scores on the MCIC was also assessed . RESULTS The MCIC of the PI-NRS ranged from 3.5 to 4.7 points in ( sub ) acute patients and 2.5 to 4.5 points in chronic patients with low back pain . The MCIC of the QBPDS was estimated between 17.5 to 32.9 points and 8.5 to 24.6 points for ( sub ) acute and chronic patients with low back pain . The MCIC for the EQ ranged from 0.07 to 0.58 in ( sub ) acute patients and 0.09 to 0.28 in patients with chronic low back pain . CONCLUSION Reporting the percentage of patients who have made a MCIC adds to the interpretability of study results . We present a range of MCIC values and advocate the choice of a single MCIC value according to the specific context .
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Outcome_Pain
pain intensity
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Outcome_Mental
functional status
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Outcome_Physical
health status
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Outcome_Physical
Minimal Clinically Important Change ( MCIC )
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Outcome_Pain
pain intensity numerical rating scale ( PI-NRS )
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Outcome_Mental
Quebec Back Pain Disability Scale ( QBPDS
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Outcome_Physical
)
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Outcome_Physical
Euroqol ( EQ )
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Outcome_Mental
MCIC of the QBPDS
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Participant_Condition
low back pain
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Participant_Condition
low back pain
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Participant_Sample-size
442
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Participant_Condition
low back pain
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Participant_Condition
low back pain