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document
Event-related potential indices of auditory selective attention in dependent amphetamine users . BACKGROUND The aim of the present study was to further investigate a previously reported attention-related impairment in dependent amphetamine users using event-related potential ( ERP ) indices of selective attention . METHODS ERPs were recorded during an auditory selective attention task ( SAT ) that involved detecting infrequent long-duration target tones presented among short-duration tones that varied in location ( left vs. right ear ) and pitch ( low vs. high ) . Amphetamine users ( n = 19 ) were divided into two groups , high dependence ( n = 10 ) and low dependence ( n = 10 ) , based on amphetamine Severity of Dependence Scale scores , and compared to an age-matched control group ( n = 9 ) . RESULTS The high-dependence group showed slowed reaction time and reduced early processing negativity and peak N1 amplitude to location-relevant nontarget stimuli . Poor performance on the SAT was highly correlated with deficits in early processing , which were also related to poor performance on the Wechsler Memory Scale Attention/Concentration index . CONCLUSIONS It is suggested that severely dependent users suffer an inability to selectively enhance the sensory processing of relevant auditory information . This may produce poor automatic preferential processing of relevant information and increase load on limited attentional resources .
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Intervention_Educational
auditory selective attention task ( SAT )
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Outcome_Mental
event-related potential ( ERP ) indices
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Outcome_Mental
slowed reaction time
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Outcome_Mental
reduced early processing negativity
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Outcome_Mental
peak N1 amplitude
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Outcome_Mental
Wechsler Memory Scale Attention/Concentration index
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Participant_Condition
dependent amphetamine
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Participant_Condition
dependent amphetamine
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Participant_Sample-size
19
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Participant_Sample-size
10
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Participant_Sample-size
10
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Participant_Condition
9