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document
Micronized flavonoids in pain control after hemorrhoidectomy : a prospective randomized controlled study . PURPOSE We conducted a prospective randomized controlled study to evaluate the effect of micronized flavonoid fractions ( MFF ) on pain after hemorrhoidectomy . METHODS The subjects were 112 consecutive patients randomly assigned either to receive MFF ( group 1 ) for 1 week or not to receive MFF , as a control ( group 2 ) , after hemorrhoidectomy , The severity of pain and the number of intramuscular analgesic injections required were recorded for the first 3 days , then 1 week after hemorrhoidectomy . The number of days that intramuscular analgesic injections were required , hospital stay , and patient satisfaction were also assessed . RESULTS On postoperative day ( POD ) 1 , there were no significant differences between the parameters of the two groups , but on PODs 2 and 3 , both the pain score ( P = 0.033 and P = 0.011 , respectively ) and the number of patients who required intramuscular analgesic injections were significantly less in group 1 ( P = 0.022 and P = 0.007 , respectively ) . Moreover , the hospital stay was shorter and patient satisfaction was superior in group 1 ( P = 0.001 and P = 0.001 , respectively ) . After 1 week , the pain score and number of intramuscular analgesic injections given were significantly less in group 1 ( P = 0.001 and P = 0.021 ) . CONCLUSION Using MFF after hemorrhoidectomy reduced the severity of pain and intramuscular analgesic requirement .
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Intervention_Pharmacological
Micronized flavonoids
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Intervention_Pharmacological
micronized flavonoid fractions ( MFF )
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Intervention_Pharmacological
MFF
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Intervention_Pharmacological
MFF
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Intervention_Physical
The severity of pain
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Intervention_Physical
the number of intramuscular analgesic injections required were recorded for the first 3 days , then 1 week after hemorrhoidectomy
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Intervention_Pharmacological
MFF
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Outcome_Pain
pain control
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Outcome_Pain
pain
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Outcome_Pain
severity of pain and the number of intramuscular analgesic injections
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Outcome_Mental
number of days that
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Outcome_Other
intramuscular analgesic injections
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Outcome_Mental
were required
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Outcome_Mental
hospital stay
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Outcome_Mental
patient satisfaction
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Outcome_Pain
pain score
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Outcome_Other
intramuscular analgesic injections
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Outcome_Mental
hospital stay
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Outcome_Other
patient satisfaction
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Outcome_Pain
pain score
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Outcome_Pain
intramuscular analgesic injections
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Outcome_Pain
severity of pain
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Outcome_Pain
intramuscular analgesic requirement
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Participant_Condition
after hemorrhoidectomy :