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document
The effectiveness of a calcium sodium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity : a pilot study . BACKGROUND NovaMin ( NovaMin Technology , Alachua , Fla. ) was introduced into the dental market as a desensitizer in December 2004 . However , to the authors ' knowledge , no researchers yet have evaluated the effectiveness of 100 percent NovaMin powder with NovaMin-containing toothpaste in reducing dentin hypersensitivity compared with the effectiveness of NovaMin-containing toothpaste only and a desensitizing toothpaste containing potassium nitrate as a control . METHODS The authors divided 60 participants randomly into three groups : NovaMin powder with NovaMin-containing toothpaste ( group 1 ) , a placebo powder with NovaMin-containing toothpaste ( group 2 ) and a placebo powder with the control toothpaste ( group 3 ) . The authors used tactile and cold stimuli and a visual analog scale to evaluate participants ' pain at baseline , immediately after powder application and at one week , two weeks and four weeks after powder application . They analyzed data by using Friedman and Wilcoxon signed-rank tests for within-group comparison . They used Kruskal-Wallis and Mann-Whitney U tests for between-group comparison . They considered P < .05 to be statistically significant . RESULTS Groups 1 and 2 showed significant hypersensitivity reduction over baseline at all time points . Group 3 showed significant hypersensitivity reduction at one week onward . Group 1 showed significant improvement compared with groups 2 and 3 , except for response to tactile stimulus at four weeks with group 2 . Between groups 2 and 3 , there were significant differences at two and four weeks . CONCLUSIONS and CLINICAL IMPLICATIONS The use of NovaMin powder and NovaMin-containing toothpaste for hypersensitivity reduction is more effective than the use of a desensitizing toothpaste containing potassium nitrate and fluoride .
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Intervention_Pharmacological
NovaMin powder
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Intervention_Pharmacological
NovaMin-containing toothpaste
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Intervention_Control
placebo powder
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Intervention_Pharmacological
NovaMin-containing toothpaste
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Intervention_Pharmacological
control toothpaste
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Outcome_Other
effectiveness
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Outcome_Pain
tactile and cold stimuli
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Outcome_Pain
visual analog scale
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Outcome_Pain
Friedman and Wilcoxon signed-rank tests
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Outcome_Physical
hypersensitivity reduction
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Outcome_Physical
hypersensitivity reduction
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Outcome_Physical
tactile stimulus