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document
A shortened versus standard matched postpartum magnesium sulphate regimen in the treatment of eclampsia : a randomised controlled trial . Magnesium sulphate is currently the most ideal drug for the treatment of eclampsia but its use in Nigeria is still limited due its cost and clinicians inexperience with the drug . The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011 , 98 eclamptic mothers presenting at the labour ward of the University of Maiduguri Teaching Hospital were randomised to receive either the standard Pritchard regimen of magnesium sulphate or a shortened postpartum course in which only two doses of intramuscular magnesium sulphate is given four hours apart . The maternal and fetal outcomes were compared . The primary outcome measure was recurrence of fits . The recurrence of fits and other maternal complications were similar in the two groups . The total dosage of magnesium sulphate in the shortened group was reduced by 40 % in 66 % of patients . The shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in the management of eclampsia .
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Intervention_Pharmacological
postpartum magnesium sulphate regimen
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Intervention_Pharmacological
Magnesium sulphate
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Intervention_Pharmacological
magnesium sulphate
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Intervention_Pharmacological
standard Pritchard regimen of magnesium sulphate
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Intervention_Pharmacological
intramuscular magnesium sulphate
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Intervention_Pharmacological
magnesium sulphate
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Intervention_Pharmacological
magnesium sulphate
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Outcome_Physical
recurrence of fits
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Outcome_Physical
recurrence of fits
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Outcome_Adverse-effects
maternal complications
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Outcome_Other
total dosage of magnesium sulphate
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Outcome_Other
reduced
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Outcome_Physical
sulphate
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Outcome_Other
effective
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Outcome_Physical
management of eclampsia