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document
Scales for the assessment of neuroleptic response in schizophrenic children : specific measures derived from the CPRS . This article reports the psychometric properties of two scales for rating positive and negative schizophrenic signs and symptoms . These Positive and Negative Syndrome Scales consist of items selected from the Children 's Psychiatric Rating Scale ( CPRS ) , which contains items covering a wide range of childhood psychopathology . CPRS rating data were analyzed for 19 schizophrenic children , 16 males and 3 females , mean age 8.9 years ( range 5.5-11.7 ) , evaluated in a double-blind , placebo-controlled crossover study of haloperidol . We describe the item composition and coherence of each scale , the interrater reliabilities of clinicians using the scales , and the sensitivity of the scales for resolving treatment response . Schizophrenic children showed both positive and negative signs and symptoms , and both improved with neuroleptic treatment .
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
haloperidol
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Outcome_Physical
neuroleptic
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Outcome_Other
response
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Outcome_Physical
Positive and Negative Syndrome Scales
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Outcome_Physical
positive and negative signs and symptoms
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Outcome_Physical
neuroleptic treatment
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Participant_Condition
schizophrenic
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Participant_Age
children
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Participant_Sample-size
19
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Participant_Condition
schizophrenic
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Participant_Age
children
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Participant_Sample-size
16
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Participant_Sex
males
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Participant_Sample-size
3
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Participant_Sex
females
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Participant_Age
mean age 8.9 years
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Participant_Age
5.5-11.7
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Participant_Condition
Schizophrenic
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Participant_Age
children