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document
Prospective randomized evaluation of diode-laser and cryotherapy in prethreshold retinopathy of prematurity . PURPOSE To study the efficacy of indirect diode laser photocoagulation and cryotherapy in prethreshold retinopathy of prematurity ( ROP ) . METHODS Thirty-six eyes of 18 premature infants less than 34 weeks gestational age and/or less than 1600 g birth weight with prethreshold ROP were prospectively randomized to treatment with either indirect laser photocoagulation or cryotherapy . Prethreshold ROP was defined as any stage of ROP in zone I with plus disease ; or stage 3 with three or more contiguous clock hours or five or more total clock hours of involvement of retina in zone II with plus disease but less than threshold disease . Regression of the ROP was assessed for a minimum period of 6 months . RESULTS Regression of ROP occurred in all 36 eyes ( 100 % ) in both groups . CONCLUSIONS Excellent results are achieved if ROP is treated at the prethreshold stage with both indirect laser photocoagulation and cryotherapy . Although laser has definite advantages , cryotherapy can be considered as an alternative modality of treatment in developing countries due to economic reasons .
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Intervention_Physical
indirect laser photocoagulation
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Intervention_Physical
cryotherapy
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Outcome_Physical
prethreshold retinopathy
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Outcome_Physical
prethreshold retinopathy of prematurity ( ROP )
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Outcome_Physical
Regression of the ROP
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Outcome_Physical
Regression of ROP
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Outcome_Other
ROP
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Participant_Condition
prethreshold retinopathy of prematurity
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Participant_Condition
prethreshold retinopathy of prematurity ( ROP )
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Participant_Sample-size
18 premature infants
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Participant_Age
34 weeks gestational age
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Participant_Condition
prethreshold ROP
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Participant_Condition
Regression of ROP