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document
A randomized controlled trial of cognitive-behavioral therapy versus treatment as usual for adolescents with autism spectrum disorders and comorbid anxiety . OBJECTIVE Examine the efficacy of a personalized , modular cognitive-behavioral therapy ( CBT ) protocol among early adolescents with high-functioning autism spectrum disorders ( ASDs ) and co-occurring anxiety relative to treatment as usual ( TAU ) . METHOD Thirty-one children ( 11-16 years ) with ASD and clinically significant anxiety were randomly assigned to receive 16 weekly CBT sessions or an equivalent duration of TAU . Participants were assessed by blinded raters at screening , posttreatment , and 1-month follow-up . RESULTS Youth randomized to CBT demonstrated superior improvement across primary outcomes relative to those receiving TAU . Eleven of 16 adolescents randomized to CBT were treatment responders , versus 4 of 15 in the TAU condition . Gains were maintained at 1-month follow-up for CBT responders . CONCLUSIONS These data extend findings of the promising effects of CBT in anxious youth with ASD to early adolescents .
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Intervention_Educational
cognitive-behavioral therapy
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Intervention_Physical
versus
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Intervention_Control
treatment as usual
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Intervention_Educational
personalized , modular cognitive-behavioral therapy ( CBT ) protocol
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Intervention_Control
treatment as usual ( TAU )
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Intervention_Educational
CBT sessions
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Intervention_Physical
or an
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Intervention_Control
equivalent duration of TAU
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Intervention_Educational
CBT
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Intervention_Control
TAU
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Intervention_Educational
CBT
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Intervention_Control
TAU
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Intervention_Educational
CBT
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Outcome_Mental
autism spectrum disorders and comorbid anxiety .
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Outcome_Other
efficacy
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Outcome_Other
superior improvement
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Outcome_Mental
primary outcomes
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Outcome_Other
Gains
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Outcome_Other
promising effects
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Participant_Age
adolescents
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Participant_Condition
autism spectrum disorders
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Participant_Age
adolescents
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Participant_Condition
high-functioning autism spectrum disorders ( ASDs )
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Participant_Sample-size
Thirty-one children
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Participant_Age
( 11-16 years )
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Participant_Condition
ASD
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Participant_Condition
ASD
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Participant_Age
adolescents