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A brief adherence intervention that improved glycemic control : mediation by patterns of adherence . This study examined whether longitudinal adherence profiles mediated the relationship between a brief adherence intervention and glycemic control among patients with type 2 diabetes . Adherence was assessed using the Medication Event Monitoring System . Longitudinal analysis via growth curve mixture modeling was carried out to classify patients according to patterns of adherence to oral hypoglycemic agents . Hemoglobin A1c assays were used to measure glycemic control as the clinical outcome . Across the whole sample , longitudinal adherence profiles mediated 35.2 % ( 13.2 , 81.0 % ) of the effect of a brief adherence intervention on glycemic control [ from odds ratio ( OR ) = 8.48 , 95 % confidence interval ( CI ) ( 3.24 , 22.2 ) to 4.00 , 95 % CI ( 1.34 , 11.93 ) ] . Our results suggest that patients in the intervention had better glycemic control largely due to their greater likelihood of adherence to oral hypoglycemic agents .
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Intervention_Educational
brief adherence intervention
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Intervention_Educational
adherence intervention
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Intervention_Educational
Adherence
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Intervention_Pharmacological
adherence to oral hypoglycemic agents
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Outcome_Physical
glycemic control
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Outcome_Physical
glycemic control
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Outcome_Physical
glycemic control
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Outcome_Physical
glycemic control
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Participant_Condition
type 2 diabetes