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document
A prospective , randomized study of 5-fluorouracil and filtration surgery . Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment . Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group . Corneal epithelial defects were as common with a low dose as with higher doses previously described .
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Intervention_Pharmacological
5-fluorouracil
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Intervention_Surgical
filtration surgery
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Intervention_Pharmacological
subconjunctival 5-FU
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Intervention_Control
no antimetabolite treatment
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Intervention_Pharmacological
5-FU
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Outcome_Physical
postoperative intraocular pressure
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Outcome_Physical
intraocular pressure
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Outcome_Physical
Corneal epithelial defects
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Participant_Condition
5-fluorouracil and filtration surgery .