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document
Continuous glucose monitoring in acute coronary syndrome . BACKGROUND Diabetes mellitus is an independent risk factor for cardiovascular disease . OBJECTIVE To compare the efficacy of devices for continuous glucose monitoring and capillary glucose monitoring in hospitalized patients with acute coronary syndrome using the following parameters : time to achieve normoglycemia , period of time in normoglycemia , and episodes of hypoglycemia . METHODS We performed a pilot , non-randomized , unblinded clinical trial that included 16 patients with acute coronary artery syndrome , a capillary or venous blood glucose ≥ 140 mg/dl , and treatment with a continuous infusion of fast acting human insulin . These patients were randomized into 2 groups : a conventional group , in which capillary measurement and recording as well as insulin adjustment were made every 4h , and an intervention group , in which measurement and recording as well as insulin adjustment were made every hour with a subcutaneous continuous monitoring system . Student 's t-test was applied for mean differences and the X ( 2 ) test for qualitative variables . RESULTS We observed a statistically significant difference in the mean time for achieving normoglycemia , favoring the conventional group with a P = 0.02 . CONCLUSION Continuous monitoring systems are as useful as capillary monitoring for achieving normoglycemia .
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Outcome_Other
efficacy of devices
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Outcome_Physical
time to achieve normoglycemia
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Outcome_Physical
period of time in normoglycemia
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Outcome_Physical
episodes of hypoglycemia
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Outcome_Other
Student 's t-test
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Outcome_Other
the X ( 2 ) test
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Outcome_Physical
time for achieving normoglycemia
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Participant_Condition
acute coronary syndrome
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Participant_Condition
Diabetes mellitus
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Participant_Condition
cardiovascular disease .
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Participant_Condition
hospitalized patients with acute coronary syndrome
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Participant_Sample-size
16
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Participant_Condition
acute coronary artery syndrome