79095
document
[ Randomized study on the long-term adjuvant chemotherapy with ftorafur and mitomycin C for stomach cancer : second report ] . In view of the usefulness of long-term adjuvant chemotherapy , the Cooperative Study Group of Surgical Adjuvant Chemotherapy for Gastric Cancer adopted as the second cooperative study a prospective randomized trial on three groups ; MMC alone , Futraful alone and a combination of MMC and Futraful . In the group of Futraful alone the survival and disease-free rate were improved in three years after operation , especially marked in patients with the advanced stage . Moreover , the survival and disease-free rate in the group of the combination therapy were higher than those in the group of Futraful alone , and the relapse rate was lower in the former . Therefore , a long-term combined adjuvant chemotherapy with MMC and Futraful seems to be one of the most effective chemotherapy regimens for resectable advanced gastric cancer .
79096
Intervention_Physical
long-term adjuvant chemotherapy
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Intervention_Physical
ftorafur
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Intervention_Pharmacological
mitomycin C
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Intervention_Pharmacological
long-term adjuvant chemotherapy
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Intervention_Pharmacological
MMC alone
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Intervention_Pharmacological
Futraful alone
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Intervention_Pharmacological
MMC
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Intervention_Pharmacological
Futraful
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Intervention_Pharmacological
Futraful
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Intervention_Pharmacological
combination therapy
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Intervention_Pharmacological
Futraful
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Intervention_Psychological
long-term combined adjuvant chemotherapy with MMC and Futraful
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Intervention_Psychological
chemotherapy
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Outcome_Mortality
survival
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Outcome_Mortality
disease-free rate
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Outcome_Mortality
survival
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Outcome_Mortality
disease-free rate
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Outcome_Physical
relapse rate