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Comparison of laser photocoagulation for diabetic retinopathy using 532-nm standard laser versus multispot pattern scan laser . PURPOSE The purpose of this study was to compare the efficacy , collateral damage , and convenience of panretinal photocoagulation for proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy using a 532-nm solid-state green laser ( GLX ) versus a multispot 532-nm pattern scan laser ( PASCAL ) . METHODS This study was a prospective randomized clinical trial . Sixty patients with bilaterally symmetrical proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy participated . Each patient underwent panretinal photocoagulation : one eye with GLX and the other with PASCAL , two sittings per eye . Grade 3 burns with a 200-mum spot size were placed with both modalities . The fluence , pain using the visual analog scale , time , laser spot spread with infrared images , and retinal sensitivity were compared . RESULTS Pattern scan laser and GLX required an average fluence of 40.33 vs 191 J/cm ( 2 ) , respectively . Average time required per sitting was 1.43 minutes with PASCAL and 4.53 minutes with GLX . Average visual analog scale reading for GLX was 4.6 , whereas that for PASCAL was 0.33 . Heidelberg retinal angiography images showed the spot spread as being 430 versus 310 microm at 3 months with GLX and PASCAL . The eyes treated with PASCAL showed higher average retinal sensitivity in the central 15 degrees and 15 degrees to 30 degrees zones ( 25.08 and 22.08 dB , respectively ) than the eyes treated with GLX ( 23.16 and 17.14 dB ) , respectively . CONCLUSION Pattern scan laser showed lesser collateral damage and similar regression of retinopathy compared with GLX . Pattern scan laser treatment was less time consuming and less painful for the patient compared with GLX .
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Intervention_Physical
laser photocoagulation
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Intervention_Physical
solid-state green laser ( GLX )
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Intervention_Physical
multispot 532-nm pattern scan laser
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Intervention_Physical
one eye with GLX
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Intervention_Physical
PASCAL
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Outcome_Pain
fluence , pain using the visual analog scale
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Outcome_Other
time
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Outcome_Other
laser spot spread
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Outcome_Physical
retinal sensitivity
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Outcome_Other
average fluence
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Outcome_Other
Average time required per sitting
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Outcome_Other
Average visual analog scale reading
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Outcome_Physical
spot spread
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Outcome_Physical
average retinal sensitivity
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Outcome_Physical
regression of retinopathy
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Participant_Condition
proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy