73282
document
Effect of direct current pulse stimulating acupoints of JiaJi ( T10-13 ) and Ciliao ( BL 32 ) with Han 's Acupoint Nerve Stimulator on labour pain in women : a randomized controlled clinical study . OBJECTIVE To assess the clinical effect and safety of direct current ( DC ) pulse produced by Han 's Acupoint Nerve Stimulator in reduction ( HANS ) of labor pain . METHODS Totally 120 participants were enrolled in this clinical trial , and were randomly divided into 4 groups including : HANS group , patient controlled intravenous analgesia ( PCIA ) group , patient-controlled epidural analgesia ( PCEA ) group and control group . The HANS group was treated by stimulating the acupoints of JiaJi ( T10-L3 ) and Ciliao ( BL 32 ) with DC pulse of 100 Hz and 15-30 mA produced by a portable battery-powered Han 's Acupoint Nerve Stimulator for 30 min . The PCIA group was intravenously infused Ondansetron ( 8 mg ) for 5 min , then tramadol injection ( 1.5 mg/kg ) was slowly dripped by using BaxterAP II electronic pump with 50 mL tramadol ( 0.70 % ) + ondansetron ( 8 mg ) , background infusion 2 mL/h , PCA dose of 2 mL , lockout interval of 10 min . In PCEA group , women received intrathecal injection ropivacaine ( 3 mg ) in L2-3 , and epidural catheter was connected to BaxterAP II electronic pump , with 100 mL Ropivacaine ( 0.1 % ) and Sufentanil ( 50 ug ) , background infusion 5 mL , Patient controlled analgesia ( PCA ) dose of 5 mL , lockout interval of 10 min . The control group was not received analgesia . The visual analogue scale ( VAS ) , stage and manner of labor , Apgar score of newborn , neonatal weights , oxytocin dosage , postpartum hemorrhage and side effects were monitored in all groups . RESULTS The vital signs were all stable in the four analgesic groups . After analgesia , there was statistical difference in VAS score between HANS group and control group , between PCEA group and the control group , between PCIA group and control group . The analgesic effect in the PCEA group was significantly better than that of other two groups . The second stage of labor in the PCEA group was longer than the other three groups , showing significant difference between them . The Apgar score of newborn 1 min after birth in the PCIA group was slightly lower than that of the other two groups , showing significant difference between them . The neonatal weights between four groups were not significantly different . The rate of cesarean section in the control group was significantly higher than that of the labor analgesia group , there was statistically difference in four groups . The number of PCIA group that used oxytocin was lower than that of other three groups . There was no significant difference in postpartum hemorrhage between four groups . The side effects of the PCEA group were itching , uroschesis and neonatal asphyxia and PCIA group were nausea and vomiting and neonatal asphyxia . However , fewer side-effects were observed in the HANS group . CONCLUSION The DC pulse produced by HANS may be a non-pharmacological alternative to labor pain with fewer side effects .
73283
Intervention_Physical
direct current pulse stimulating acupoints of JiaJi
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Intervention_Physical
Han 's Acupoint Nerve Stimulator
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Intervention_Physical
direct current ( DC ) pulse produced by Han 's Acupoint Nerve Stimulator
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Intervention_Pharmacological
HANS group
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Intervention_Pharmacological
patient controlled intravenous analgesia ( PCIA ) group
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Intervention_Pharmacological
patient-controlled epidural analgesia ( PCEA )
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Intervention_Physical
HANS
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Intervention_Physical
acupoints of JiaJi
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Intervention_Physical
Ciliao
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Intervention_Physical
DC pulse
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Intervention_Physical
portable battery-powered Han 's Acupoint Nerve Stimulator
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Intervention_Physical
PCIA
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Intervention_Pharmacological
Ondansetron
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Intervention_Pharmacological
tramadol injection
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Intervention_Pharmacological
tramadol
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Intervention_Pharmacological
ondansetron
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Intervention_Pharmacological
PCEA
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Intervention_Pharmacological
injection ropivacaine
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Intervention_Pharmacological
Ropivacaine
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Intervention_Pharmacological
Sufentanil
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Intervention_Pharmacological
Patient controlled analgesia ( PCA )
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Intervention_Physical
HANS
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Intervention_Control
control
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Intervention_Physical
PCEA
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Intervention_Control
control
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Intervention_Physical
PCIA
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Intervention_Control
control
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Intervention_Physical
PCEA
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Intervention_Physical
PCEA
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Intervention_Physical
PCIA
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Intervention_Physical
PCIA
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Intervention_Physical
PCEA
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Intervention_Physical
PCIA
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Intervention_Physical
HANS
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Intervention_Physical
HANS
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Outcome_Pain
labour pain
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Outcome_Pain
labor pain .
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Outcome_Physical
The
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Outcome_Pain
visual analogue scale ( VAS )
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Outcome_Physical
, stage and manner of labor , Apgar score of newborn , neonatal weights , oxytocin dosage ,
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Outcome_Adverse-effects
postpartum hemorrhage and side effects
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Outcome_Pain
VAS score
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Outcome_Pain
analgesic effect
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Outcome_Physical
neonatal weights
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Outcome_Physical
rate of cesarean section
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Outcome_Other
used oxytocin
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Outcome_Adverse-effects
postpartum hemorrhage
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Outcome_Adverse-effects
itching , uroschesis and neonatal asphyxia
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Outcome_Adverse-effects
nausea and vomiting and neonatal asphyxia .
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Outcome_Adverse-effects
side-effects
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Participant_Condition
labour pain
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Participant_Sex
women
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Participant_Sample-size
120