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document
Effects of weight reduction interventions by community pharmacists . OBJECTIVE To compare a meal replacement ( MR ) program with a conventional reduced-calorie diet ( RCD ) for weight management using the pharmacy as the setting and the pharmacist as the point of contact for dietary advice . DESIGN Randomized , controlled , open-label trial . SETTING Travis Pharmacy in Shenandoah , Iowa . PATIENTS Ninety-five patients from southwestern iowa and southeastern Nebraska were enrolled , of whom 88 were considered eligible for comparison ( by continuing through week 2 of the study ) . INTERVENTION Patients were randomized to an MR plan or a traditional RCD plan . Patients were followed for a 3-month period of active weight loss and a 10-week period of weight maintenance . Patients returned every 3 weeks for follow-up with the pharmacist , for a total of 13 visits . MAIN OUTCOME MEASURE Weight changes . RESULTS During the active weight loss phase , the MR ( n = 45 ) and RCD ( n = 43 ) groups lost a significant amount of weight , although no significant difference was found between the groups ( mean +/- standard error = 4.90 +/- 0.30 kg MR versus 4.30 +/- 0.30 kg RCD ; P = .16 ) . In the weight maintenance phase , the MR group lost 0.70 +/- 0.40 kg and the RCD group lost 0.90 +/- 0.40 kg ( P = .60 ) . Significant improvements were observed in waist circumference , systolic and diastolic blood pressure , and triglyceride levels . No significant changes were seen in high-density lipoprotein cholesterol or low-density lipoprotein cholesterol levels in either group . CONCLUSION Successful weight management can be achieved in a pharmacy setting . Both MR and RCD programs were effective .
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Intervention_Educational
weight reduction interventions
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Intervention_Educational
meal replacement ( MR ) program
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Intervention_Educational
conventional reduced-calorie diet ( RCD )
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Intervention_Educational
dietary advice
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Intervention_Educational
MR
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Intervention_Educational
RCD
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Intervention_Educational
MR
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Intervention_Educational
RCD
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Outcome_Physical
Weight changes .
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Outcome_Physical
significant amount of weight
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Outcome_Physical
waist circumference , systolic and diastolic blood pressure , and triglyceride levels .
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Outcome_Physical
high-density lipoprotein cholesterol or low-density lipoprotein cholesterol levels
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Participant_Sample-size
Ninety-five
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Participant_Sample-size
88