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document
Comparison of an allograft in an experimental putty carrier and a bovine-derived xenograft used in ridge preservation : a clinical and histologic study in humans . PURPOSE The aim of this randomized , controlled , blinded clinical study was to compare ridge dimensions and histologic characteristics of ridges preserved with 2 different graft materials . MATERIALS AND METHODS Twenty-four subjects , each requiring a nonmolar extraction and delayed implant placement , were randomly selected to receive ridge preservation treatment with either an allograft in an experimental putty carrier plus a calcium sulfate barrier ( PUT ) or a bovine-derived xenograft ( BDX ) plus a collagen membrane . Horizontal and vertical ridge dimensions were determined using a digital caliper and a template . At 4 months postextraction , a trephine core was obtained for histologic analysis . RESULTS The average ridge width decreased by 0.50 mm for both groups ( P < .05 ) . The midbuccal vertical change for the PUT group was a loss of 0.3+/-0.7 mm versus a gain of 0.7+/-1.2 mm for the BDX group , a difference of 1.0 mm ( P > .05 ) . Histologic analysis revealed vital bone in the PUT group of about 61 % +/-9 % versus 26 % +/-20 % for the BDX group ( P < .05 ) . DISCUSSION Greater vital bone fill in the PUT group may be attributable to earlier and greater vascular invasion of the carrier material . The putty material was characterized by ease of handling , simple placement , and enhanced graft particle containment . CONCLUSIONS Allograft mixed with an experimental putty carrier produced significantly more vital bone fill than did the use of a xenograft with no carrier material . Ridge width and height dimensions were similarly preserved with both graft materials .
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Intervention_Pharmacological
allograft
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Intervention_Psychological
experimental putty carrier and a bovine-derived xenograft
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Intervention_Physical
graft materials
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Intervention_Pharmacological
calcium sulfate barrier
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Intervention_Pharmacological
bovine-derived xenograft ( BDX )
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Intervention_Pharmacological
BDX
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Intervention_Physical
BDX
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Intervention_Pharmacological
xenograft
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Outcome_Physical
ridge dimensions and histologic characteristics of ridges
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Outcome_Physical
Horizontal and vertical ridge dimensions
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Outcome_Physical
histologic analysis
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Outcome_Physical
ridge width
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Outcome_Physical
midbuccal vertical change
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Outcome_Physical
vital bone
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Outcome_Physical
vital bone fill
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Outcome_Physical
Ridge width and height dimensions
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Participant_Condition
humans
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Participant_Sample-size
Twenty-four
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Participant_Condition
nonmolar extraction
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Participant_Condition
delayed implant placement