9803
document
Double-blind placebo-controlled trial of secretin : effects on aberrant behavior in children with autism . Secretin has been proposed as a treatment alternative for autistic spectrum disorders , but empirical support is lacking . A double-blind placebo-controlled study examined the effect of a single dose of synthetic human secretin on aberrant behavior . Parent and teacher data from the Aberrant Behavior Checklist for eight male children were analyzed for reliable change in a clinical replication series . By parent and teacher report , the majority of change occurred either on the placebo trial or reflected deterioration subsequent to secretin infusion . Repeated-measures multivariate analysis of variance results were similar . Results are consistent with other studies , suggesting that secretin may not be an effective treatment option .
9804
Intervention_Pharmacological
secretin :
9805
Intervention_Pharmacological
Secretin
9806
Intervention_Pharmacological
synthetic human secretin
9807
Intervention_Control
placebo
9808
Intervention_Pharmacological
secretin
9809
Intervention_Pharmacological
secretin
9810
Outcome_Mental
aberrant behavior in children with autism .
9811
Outcome_Mental
autistic spectrum disorders
9812
Outcome_Mental
aberrant behavior .
9813
Outcome_Mental
Aberrant Behavior Checklist
9814
Participant_Condition
children with autism .