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document
Excimer laser trabeculotomy vs 180 degrees selective laser trabeculoplasty in primary open-angle glaucoma . A 2-year randomized , controlled trial . PURPOSE To compare the effectiveness and safety of excimer laser trabeculotomy ( ELT ) ab interno vs selective laser trabeculoplasty ( SLT ) over 24 months of follow-up in patients with primary open-angle glaucoma ( POAG ) refractory to medical therapy . PATIENTS AND METHODS This prospective , randomized study included 30 consecutive eyes assigned randomly to either ELT or SLT group . ELT was carried out using a XeCl Excimer Laser with an emission wavelength of 308 nm . Eight spots were equally distributed at a distance of 500 microm from one another over the anterior trabeculum . The SLT patients were treated with a frequency-doubled q-switched neodymium : yytrium-aluminum-garnet laser ( wavelength 532 nm ) . Approximately 50 adjacent , but not overlapping , laser spots were distributed over 180 degrees of the trabecular meshwork , using an energy level ranging from 0.7 to 1.0 mJ per pulse . The main outcome measure was intraocular pressure ( IOP ) lowering after ELT and SLT . Success was defined as > or=20 % reduction in IOP without further glaucoma intervention . RESULTS At 24 months , complete success rates were 53.3 % for the ELT group and 40 % for the SLT group ( P=0.35 , Fisher 's exact test ) ; qualified success rates were 33.3 % for the ELT and 26.6 % for the SLT group ( P=0.5 , Fisher 's exact test ) .Mean IOP decreased from 25.0+/-1.9 to 17.6+/-2.2 mmHg ( -29.6 % ; P < 0.0001 ) in the ELT group and from 23.9+/-0.9 to 19.1+/-1.8 mmHg ( -21 % ; P < 0.0001 ) in the SLT group . CONCLUSIONS Both ELT and SLT proved to be effective techniques in the treatment of POAG refractory to medical therapy .
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Intervention_Surgical
Excimer laser trabeculotomy
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Intervention_Surgical
180 degrees selective laser trabeculoplasty
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Intervention_Surgical
excimer laser trabeculotomy ( ELT )
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Intervention_Physical
selective laser trabeculoplasty ( SLT )
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Intervention_Surgical
ELT
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Intervention_Control
SLT
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Intervention_Surgical
ELT
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Intervention_Physical
was carried out using a
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Intervention_Surgical
XeCl Excimer Laser
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Intervention_Physical
with an emission
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Intervention_Surgical
wavelength of 308 nm
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Intervention_Surgical
frequency-doubled q-switched neodymium : yytrium-aluminum-garnet laser ( wavelength 532 nm )
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Outcome_Other
effectiveness and safety
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Outcome_Physical
intraocular pressure ( IOP ) lowering after ELT and SLT .
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Outcome_Physical
reduction in IOP
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Outcome_Physical
success rates
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Outcome_Physical
qualified success rates
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Outcome_Physical
test ) .Mean IOP decreased
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Participant_Condition
patients with primary open-angle glaucoma ( POAG ) refractory to medical therapy
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Participant_Sample-size
30