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document
Pharmacist directed home medication reviews in patients with chronic heart failure : a randomised clinical trial . BACKGROUND Chronic heart failure ( CHF ) accounts for significant morbidity , mortality and health expenditure . Furthermore , patients with CHF are often on numerous pharmacological agents for their comorbidities . The objective of this study was to determine whether a pharmacist directed home medication review intervention had positive effects on CHF patient outcomes . METHODS A total of 120 patients hospitalised for CHF were randomised to receive a pharmacist directed post-discharge home medication review ( n = 64 , 53.3 % ) or standard care ( n = 56 , 46.7 % ) . Participants were followed for 6 months . Primary outcomes were death , CHF hospitalisation and length of hospital stay . RESULTS There were no between group differences in mortality ( hazard ratio = 1.41 , 0.50 to 3.97 ; P = 0.514 ) or CHF hospitalizations ( incidence rate ratio [ IRR ] = 1.74 95 % CI : 0.85-3.60 P = 0.131 ) over the 6 month follow-up period . Days of hospital stay for CHF exacerbations in the 6 month follow-up were significantly greater in the intervention group ( IRR = 2.34 95 % CI : 1.80-3.05 P = 0.000 ) . CONCLUSIONS Post-discharge pharmacy directed home medication review appeared to have no effect on mortality and health care utilisation above that achieved with standard care . The post-acute management of CHF must be a collaborative multi-disciplinary effort by the health care team as it is the additive effect of interventions that are most effective .
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Intervention_Pharmacological
home medication
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Intervention_Pharmacological
home medication
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Intervention_Pharmacological
home medication
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Intervention_Control
standard care
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Intervention_Pharmacological
home medication
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Outcome_Physical
CHF hospitalisation
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Outcome_Mortality
mortality
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Outcome_Physical
CHF hospitalizations
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Outcome_Other
Days of hospital stay for CHF exacerbations
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Participant_Condition
patients with chronic heart failure :
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Participant_Condition
Chronic heart failure ( CHF )
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Participant_Condition
patients with CHF
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Participant_Condition
CHF patient
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Participant_Sample-size
120
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Participant_Condition
CHF