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document
Influence of Aloe arborescens Mill . extract on selected parameters of pro-oxidant-antioxidant equilibrium and cytokine synthesis in rowers . This investigation examined the effect of supplementation with Biostimine , extract from Aloe arborescens Mill . leaves , on the levels of pro-oxidant-antioxidant equilibrium markers and anti- and proinflammatory cytokines in rowers subjected to exhaustive exercise . This double-blind study included 18 members of the Polish Rowing Team . Subjects were randomly assigned to the supplemented group ( n = 9 ) , which received one ampoule of Biostimine once daily for 4 weeks , or to the placebo group ( n = 9 ) . Subjects performed a 2,000-meter-maximum test on a rowing ergometer at the beginning and end of the preparatory camp . Blood samples were obtained from the antecubital vein before each exercise test , 1 min after completing the test and after a 24-hr recovery period . Superoxide dismutase and glutathione peroxidase activity as well as the concentration of thiobarbituric acid reactive substances ( TBARS ) were assessed in erythrocytes . In addition , total antioxidant capacity ( TAC ) and creatine kinase activity were measured in plasma samples , and cytokine ( IL-6 , IL-10 ) concentrations were determined in the serum . Before and after Biostimine supplementation , exercise significantly increased the values of SOD , IL-6 , IL-10 , and TBARS in both groups . However , postexercise and recovery levels of TBARS were significantly lower in athletes receiving Biostimine than in controls . After supplementation , TAC was the only variable with the level being significantly higher in the supplemented group than in the placebo group . Consequently , we can conclude that Biostimine supplementation reduces the postexercise level of TBARS by increasing the antioxidant activity of plasma but has no effect on inflammatory markers .
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Intervention_Pharmacological
Aloe arborescens Mill . extract
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Intervention_Pharmacological
supplementation with Biostimine , extract from Aloe arborescens Mill . leaves
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Intervention_Pharmacological
Biostimine
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Intervention_Control
placebo
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Intervention_Pharmacological
Biostimine supplementation
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Intervention_Pharmacological
Biostimine
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Intervention_Control
placebo
58040
Intervention_Pharmacological
Biostimine supplementation
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Outcome_Physical
pro-oxidant-antioxidant equilibrium
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Outcome_Physical
cytokine synthesis
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Outcome_Physical
pro-oxidant-antioxidant equilibrium markers
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Outcome_Physical
proinflammatory cytokines
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Outcome_Physical
Superoxide dismutase and glutathione peroxidase activity
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Outcome_Physical
concentration of thiobarbituric acid reactive substances ( TBARS )
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Outcome_Physical
total antioxidant capacity ( TAC )
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Outcome_Physical
creatine kinase activity
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Outcome_Physical
cytokine ( IL-6 , IL-10 ) concentrations
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Outcome_Physical
values of SOD , IL-6 , IL-10 , and TBARS
58051
Outcome_Physical
TBARS
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Outcome_Physical
TAC
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Outcome_Physical
TBARS
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Outcome_Physical
antioxidant activity of plasma
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Outcome_Physical
inflammatory markers
58056
Participant_Condition
rowers .
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Participant_Condition
rowers subjected to exhaustive exercise .