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document
[ Effect of zero-balanced ultrafiltration and modified ultrafiltration on pulmonary function after cardiac surgery in infants ] . OBJECTIVE To determine the protective effect of zero-balanced ultrafiltration and modified ultrafiltration on infants ' pulmonary function after cardiac surgery . METHODS Sixty infants with congenital heart diseases were randomly divided into 3 groups : a zero-balanced ultrafiltration group ( Z group ) , a modified ultrafiltration group ( M group ) and a zero-balanced ultrafiltration with modified ultrafiltration group ( Z+M group ) . Oxygenation index ( OI ) , difference of alveoli-arterial oxygen pressure ( P ( A-α ) O2 ) , static lung compliance ( Cstat ) , and airway resistance ( Raw ) were measured before caridopulmonary bypass ( CPB , T1 ) , 20 minutes after the CPB ( T2 ) , 2 h after the operation ( T3 ) , 6 h after the operation ( T4 ) and 12 h after the operation ( T5 ) . The time of mechanical ventilation was also monitored . RESULTS After the CPB , OI and Cstat in all groups decreased significantly , while Raw and P ( A-α ) O2 increased significantly . At T3 , T4 and T5 , OI and Cstat in the Z+M group were significantly higher than those in the Z group and the M group ( P < 0.05 ) , Raw and P ( A-α ) O2 in the Z+M group were significantly lower than those in the Z group and the M group ( P < 0.05 ) . The ventilation time in the Z+M group was significantly shorter than that in the Z group and the M group ( P < 0.05 ) . CONCLUSION Zero-balanced ultrafiltration and modified ultrafiltration can effectively promote the pulmonary function after cardiac surgery in infants .
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Intervention_Physical
zero-balanced ultrafiltration
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Intervention_Physical
modified ultrafiltration
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Intervention_Physical
zero-balanced ultrafiltration
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Intervention_Physical
modified ultrafiltration
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Intervention_Physical
3 groups : a zero-balanced ultrafiltration group ( Z group )
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Intervention_Physical
a modified ultrafiltration group ( M group )
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Intervention_Physical
a zero-balanced ultrafiltration with modified ultrafiltration group ( Z+M group )
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Participant_Condition
after cardiac surgery
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Participant_Age
infants
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Participant_Age
infants '
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Participant_Condition
cardiac surgery
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Participant_Sample-size
Sixty
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Participant_Age
infants
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Participant_Condition
congenital heart diseases