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document
Using a population-based cancer registry for recruitment in a pilot cancer control study . Cancer control investigations in the United States rarely use population-based registries as a resource for recruitment . A placebo-controlled , double-blind , randomized toxicity trial of tamoxifen was conducted among postmenopausal women with node negative breast cancer . To achieve the accrual goal of 140 subjects in this single institution study , the Wisconsin Cancer Reporting System ( WCRS ) , a population-based cancer registry , was used . Registry information from the last 9 years was used to identify 3,585 women who met the study criteria with respect to age , stage , and previous therapy . The vital status of identified women was confirmed using Wisconsin state death records . For identified cases , rosters were prepared and sent to the physician with a cover letter and study description . The physicians were asked to update the list and , if appropriate , to sign letters to potentially eligible and interested women . Thirty-eight percent of women receiving a letter and study information from their physicians contacted the study office about participation . Eighteen months from its initiation , 140 women were entered on study . This successful use of a population-based cancer registry illustrates an efficient recruitment method which could be modified for other cancer control/chemoprevention trials .
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
tamoxifen
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Outcome_Physical
Wisconsin Cancer Reporting System ( WCRS )
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Outcome_Other
population-based cancer registry
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Outcome_Other
efficient recruitment method
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Participant_Condition
cancer
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Participant_Condition
postmenopausal
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Participant_Condition
node negative breast cancer .
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Participant_Sample-size
140
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Participant_Condition
Cancer
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Participant_Condition
cancer
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Participant_Sex
women
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Participant_Sample-size
140
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Participant_Condition
cancer