69190
document
Most functional outcomes are similar for men and women after hip fracture : a secondary analysis of the enhancing mobility after hip fracture trial . BACKGROUND The impact of gender on functional outcomes after hip fracture is not known . We aimed to determine the extent to which gender influenced functional outcome and response to exercise in older people after hip fracture , and to determine if any differences persisted after adjusting for cognition , weight and age . METHOD Secondary analysis of data from the Enhancing Mobility After Hip Fracture trial in which older people after hip fracture received either a lower or higher intensity exercise program . Functional outcomes included physical performance and self-reported measures . Regression models were used to compare genders at baseline , week 4 and week 16 , with adjustment for baseline values , cognition , weight and age . Interaction terms were used to assess a differential impact of the intervention by gender . RESULTS Outcome data were available for 160 participants , 30 men ( 19 % ) and 130 women ( 81 % ) at baseline , with the withdrawal of 4 men ( 13 % ) and 6 women ( 5 % ) at week 16 . There were no gender differences for any baseline measures or for most of the 19 functional outcome measures at weeks 4 and 16 . At week 4 men performed better in knee extensor strength ( 2.1 kg , 95 % CI 0.6 to 3.7 , p < 0.01 ) . This difference did not persist after adjustment for body weight , however persisted after adjusting for baseline , cognition , and age ( p = 0.038 ) . At week 4 , men performed better in coordinated stability ( -10.0 error score , 95 % CI -17.6 to -2.4 , p=0.010 ) and this persisted after adjusting for baseline values only but not for cognition and age ( p = 0.073 ) . At week 16 , men performed better in coordinated stability ( -10.2 error score , 95 % CI -18.4 to -1.9 , p=0.016 ) and this persisted after adjusting only for cognitive impairment ( p = 0.029 ) but not for age and baseline ( p = 0.135 ) . There was no indication of a differential impact of intervention type on the basis of gender . CONCLUSIONS A few between gender differences were observed in strength and balance , however these appeared to be confounded by body weight , age and/or cognition .
69191
Intervention_Physical
exercise
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Intervention_Physical
analysis of data from the Enhancing Mobility After Hip Fracture trial
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Intervention_Physical
lower or higher intensity exercise program
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Outcome_Mental
functional outcome and response to exercise
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Outcome_Other
Functional outcomes
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Outcome_Other
physical performance and self-reported measures
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Outcome_Physical
no gender differences
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Outcome_Other
baseline measures
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Outcome_Mental
functional outcome measures
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Outcome_Physical
knee extensor strength
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Outcome_Other
difference did not persist
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Outcome_Physical
body weight
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Outcome_Physical
baseline
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Outcome_Other
cognition
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Outcome_Physical
age
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Outcome_Mental
coordinated stability
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Outcome_Mental
persisted
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Outcome_Other
baseline values
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Outcome_Mental
cognition
69210
Outcome_Physical
age
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Outcome_Mental
coordinated stability
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Outcome_Mental
persisted
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Outcome_Mental
cognitive impairment
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Outcome_Physical
age
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Outcome_Mental
baseline
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Outcome_Other
differential impact of intervention type
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Outcome_Physical
strength and balance
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Outcome_Physical
body weight
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Outcome_Physical
age
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Outcome_Mental
cognition
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Participant_Sex
men
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Participant_Sex
women
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Participant_Age
older
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Participant_Condition
hip fracture
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Participant_Condition
Hip Fracture
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Participant_Sample-size
160
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Participant_Sample-size
30
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Participant_Sex
men
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Participant_Sample-size
130
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Participant_Sex
women