13368
document
Pethidine versus tramadol for pain relief during labor . OBJECTIVE To evaluate and compare the analgesic efficacy and adverse effects of tramadol and pethidine in labor . METHOD Fifty-nine full term parturients were randomly assigned to one of two groups in active labor . Group 1 received 100 mg pethidine ; group 2 , 100 mg tramadol , intramuscularly . Analgesic efficacy , maternal side effects , changes in the blood pressure , heart rate , and duration of labor were assessed . RESULT At 30 and 60 min after drug administration , pain relief was greater in the pethidine group than in tramadol group . The incidence of nausea and fatigue was higher in the tramadol group . Following drug administration the decrease in systolic and diastolic blood pressure and the increase in heart rate were statistically significant in both groups . No significant difference was found between the groups when compared for duration of labor and Apgar scores . None of the neonates developed respiratory depression . CONCLUSION Pethidine seems to be a better alternative than tramadol in obstetric analgesia because of its superiority in analgesic efficacy and low incidence of maternal side effects .
13369
Intervention_Pharmacological
Pethidine versus tramadol
13370
Intervention_Pharmacological
tramadol
13371
Intervention_Pharmacological
pethidine
13372
Intervention_Pharmacological
pethidine ;
13373
Intervention_Pharmacological
tramadol
13374
Intervention_Pharmacological
pethidine
13375
Intervention_Pharmacological
tramadol
13376
Intervention_Pharmacological
tramadol
13377
Intervention_Pharmacological
Pethidine
13378
Intervention_Pharmacological
tramadol
13379
Outcome_Other
analgesic efficacy
13380
Outcome_Adverse-effects
adverse effects
13381
Outcome_Other
Analgesic efficacy
13382
Outcome_Adverse-effects
maternal side effects
13383
Outcome_Physical
changes in the blood pressure
13384
Outcome_Physical
heart rate
13385
Outcome_Physical
duration of labor
13386
Outcome_Pain
pain relief
13387
Outcome_Adverse-effects
nausea and fatigue
13388
Outcome_Physical
decrease in systolic and diastolic blood pressure
13389
Outcome_Physical
heart rate
13390
Outcome_Physical
duration of labor and Apgar scores
13391
Outcome_Physical
respiratory depression
13392
Outcome_Other
analgesic efficacy
13393
Outcome_Adverse-effects
maternal side effects
13394
Participant_Condition
pain relief during labor .
13395
Participant_Sample-size
Fifty-nine
13396
Participant_Condition
active labor