10309
document
Mandibular advancement splint improves indices of obstructive sleep apnoea and snoring but side effects are common . AIM To assess the efficacy of a mandibular advancement splint ( MAS ) in the treatment of obstructive sleep apnoea syndrome ( OSAS ) . METHODS Nineteen patients using a MAS for symptomatic OSAS underwent polysomnography , with MAS use randomised to one half of the night . Indices of snoring and OSAS were compared . Side effects , compliance and treatment response were evaluated by questionnaire . RESULTS Use of the MAS improved total respiratory disturbance index ( RDI ) from 22.2 +/- 19.8 ( SD ) events per hour to 16.5 +/- 21.4/hr ( p = 0.03 ) , supine RDI ( 30.8 +/- 23.8/hr to 18.8 +/- 22.1/hr , p = 0.01 ) , arousal index ( 25.2 +/- 18.9/hr to 19.3 +/- 14.2/hr , p = 0.01 ) and snoring intensity ( 52.7 +/- 4.1 to 50.7 +/- 2.7 dB , p = 0.02 ) but not total snore frequency ( p > 0.05 ) . Using polysomnographic criteria , MAS treatment was completely successful in four ( 21 % ) patients , partially successful in ten ( 52.6 % ) and a failure in five ( 26.3 % ) . Treatment over a median of 6.5 weeks ( range 2-48 ) was perceived as beneficial by ten of eleven partners . Fifteen patients ( 79 % ) reported side effects , 9 ( 46 % ) did not use the device every night and four ( 21 % ) used the device less than three nights per week . CONCLUSION The use of the MAS resulted in significant reductions in indices of OSAS and snoring . However , a significant number of patients had difficulty tolerating and regularly using the device .
10310
Intervention_Physical
Mandibular advancement splint
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Intervention_Physical
mandibular advancement splint ( MAS )
10312
Intervention_Physical
MAS
10313
Intervention_Physical
MAS
10314
Intervention_Physical
MAS
10315
Intervention_Physical
MAS
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Intervention_Physical
MAS
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Outcome_Physical
obstructive sleep apnoea syndrome ( OSAS ) .
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Outcome_Physical
Indices of snoring
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Outcome_Physical
OSAS
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Outcome_Adverse-effects
Side effects
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Outcome_Other
compliance
10322
Outcome_Physical
treatment response
10323
Outcome_Physical
total respiratory disturbance index ( RDI )
10324
Outcome_Physical
events per hour
10325
Outcome_Physical
supine RDI
10326
Outcome_Physical
arousal index
10327
Outcome_Physical
snoring intensity
10328
Outcome_Physical
total snore frequency
10329
Outcome_Other
completely successful
10330
Outcome_Other
partially successful
10331
Outcome_Other
failure
10332
Outcome_Adverse-effects
side effects
10333
Outcome_Physical
OSAS
10334
Outcome_Physical
snoring
10335
Participant_Condition
obstructive sleep apnoea and snoring
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Participant_Sample-size
Nineteen