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document
Effects of surfactant on biofilm formation on silicone nasal splints . Biofilms are sessile communities of bacteria embedded in self-produced extracellular polysaccharide matrix and are considered to be responsible for bacterial infections in humans . Topical surfactant use on silicone nasal splints may have a preventive effect on biofilm formation . The objective of this study is to investigate the effect of surfactant-containing nasal solutions on biofilm formation over the surface of silicone nasal splints . Forty patients were randomized after septoplasty to receive surfactant-containing saline solution ( group 1 ) or saline without surfactant ( group 2 ) . At the postoperative 48th , 72th and 96th hours , pieces of splint samples were taken and prepared for scanning electron microscopic evaluation . Biofilm formation was observed in 3 , 6 and 14 of 20 samples in group 1 ( surfactant used ) and 3 , 14 and 20 of 20 samples in group 2 ( control ) at 48th , 72th and 96th hours , respectively . Biofilm formation incidences of groups at 48th hour were similar ( p > 0.05 ) , whereas it was significantly lower at group 1 regarding 72th and 96th hours ( p < 0.05 ) . Surfactant-containing nasal solutions have an inhibitory effect on biofilm formation over the surface of silicone nasal splints especially after 48 h. Surfactant-containing nasal solutions may have an important role in nasal septal dressing in the future .
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Intervention_Pharmacological
surfactant
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Intervention_Physical
silicone nasal splints
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Intervention_Pharmacological
Biofilms
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Intervention_Surgical
septoplasty
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Intervention_Pharmacological
surfactant-containing saline solution ( group
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Intervention_Pharmacological
saline without surfactant
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Intervention_Pharmacological
Surfactant-containing nasal solutions
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Intervention_Pharmacological
Surfactant-containing nasal solutions
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Outcome_Other
Effects of surfactant
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Outcome_Physical
biofilm formation .
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Outcome_Physical
biofilm formation
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Outcome_Physical
silicone nasal splints .
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Outcome_Other
scanning electron microscopic evaluation
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Outcome_Physical
Biofilm formation
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Outcome_Physical
Biofilm formation
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Outcome_Physical
biofilm formation
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Outcome_Physical
nasal septal dressing
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Participant_Sample-size
Forty patients
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Participant_Condition
septoplasty