33850
document
Comparison of two sedation techniques in patients undergoing surgical procedures under regional anaesthesia . OBJECTIVE Intraoperative comfort and patient satisfaction during surgical procedures under regional anaesthesia can be improved with the use of supplemental intravenous sedation . The authors conducted a study to compare two sedation techniques for surgical procedures performed under regional anaesthesia , i.e. , midazolam and pethidine combination compared with midazolam and tramadol combination . METHODS Forty adult American Society of Anaesthesiologists ( ASA ) grade 1-111 patients , aged between 40-65 years undergoing surgery under regional anaesthesia ( sub-arachnoid block ) were included . The patients were randomly divided into two groups . All patients received standardized premedication , intraoperative monitoring and oxygen therapy . Group A patients received midazolam 0.03 mg/kg followed by pethidine 20 mg intravenously , and group B patients received midazolam 0.03 mg/kg followed by tramadol 20 mg intravenously after the institution of regional anaesthesia . Monitoring included ECG , blood pressure , respiratory rate , oxygen saturation and sedation score . Complications , if any , were recorded . Monitoring was continued during the recovery room stay . All patients were interviewed in the evening and time of ambulation and rating of OR experience was noted . RESULTS Data analysis showed no significant difference between pethidine and tramadol for all the haemodynamic variables ( p = > 0.05 ) . There was also no significant difference in patient 's and surgeon 's assessment of their experience . Complications and recovery characteristics also did not show any significant difference . CONCLUSION Midazolam-tramadol combination may be used as an alternative to midazolam-pethidine combination for sedation during surgical procedures performed under regional anaesthesia .
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Intervention_Pharmacological
sedation techniques
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Intervention_Pharmacological
midazolam
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Intervention_Pharmacological
pethidine combination
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Intervention_Pharmacological
midazolam
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Intervention_Pharmacological
tramadol combination
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Intervention_Pharmacological
midazolam 0.03 mg/kg followed by pethidine 20 mg intravenously
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Intervention_Pharmacological
midazolam 0.03 mg/kg followed by tramadol 20 mg
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Intervention_Pharmacological
pethidine
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Intervention_Pharmacological
tramadol
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Intervention_Pharmacological
Midazolam-tramadol combination
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Intervention_Pharmacological
midazolam-pethidine combination
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Outcome_Other
patient satisfaction
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Outcome_Other
ECG
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Outcome_Physical
blood pressure
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Outcome_Physical
respiratory rate
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Outcome_Physical
oxygen saturation
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Outcome_Other
sedation score
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Outcome_Physical
haemodynamic variables
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Outcome_Adverse-effects
Complications and recovery characteristics
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Participant_Condition
undergoing surgical procedures under regional anaesthesia
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Participant_Sample-size
Forty
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Participant_Age
40-65 years
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Participant_Condition
undergoing surgery under regional anaesthesia ( sub-arachnoid block