48153
document
Effect of total enteral nutrition on the short-term outcome of severely malnourished cirrhotics . A randomized controlled trial . Thirty-five severely malnourished cirrhotic patients were randomized to receive either enteral-tube feeding as the sole nutritional support ( n = 16 ) or an isocaloric , isonitrogenous , low-sodium standard oral diet ( n = 19 ) . Both groups were homogeneous regarding age , sex distribution , etiology of liver cirrhosis , history of previous complications , clinical status , liver and renal function , modified Child 's score , and nutritional status at admission . The enteral formula diet was energy dense , containing 40 mmol Na/day , whole protein plus branched-chain amino acids , medium- and long-chain triglycerides , and maltodextrin . It supplied 2115 kcal/day . The amount of vitamins and trace elements was at the upper limit of the recommended dietary allowances . The orally fed patients were encouraged to eat all meals served . Total enteral nutrition was well tolerated without major complications . Serum albumin and Child 's score improved in the enterally fed patients but not in controls . Mortality rate while in the hospital was lower in patients on enteral feeding than in controls ( 12 % vs 47 % ) . These results show that total enteral nutrition is safe and effective in improving the short-term clinical outcome in severely malnourished cirrhotics .
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Intervention_Pharmacological
enteral-tube feeding as the sole nutritional support
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Intervention_Pharmacological
isocaloric
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Intervention_Pharmacological
isonitrogenous
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Intervention_Pharmacological
low-sodium standard oral diet
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Intervention_Pharmacological
whole protein plus branched-chain amino acids
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Intervention_Pharmacological
medium- and long-chain triglycerides
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Intervention_Pharmacological
maltodextrin
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Intervention_Physical
It supplied 2115 kcal/day
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Intervention_Educational
The orally fed patients were encouraged to eat all meals served
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Outcome_Physical
severely malnourished cirrhotics .
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Outcome_Physical
Total enteral nutrition
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Outcome_Other
tolerated
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Outcome_Physical
Serum albumin and Child 's score
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Outcome_Mortality
Mortality rate while in the hospital
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Outcome_Other
short-term clinical outcome
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Participant_Condition
malnourished cirrhotics
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Participant_Sample-size
Thirty-five
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Participant_Condition
malnourished cirrhotic
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Participant_Condition
malnourished cirrhotics