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document
Middle cerebral arterial blood flow velocity and hemodynamics in heart surgery . The aim of this study was to evaluate the effects of propofol , isoflurane , and sevoflurane on middle cerebral arterial blood flow velocity during open heart surgery , and the relationship between these effects and hemodynamic parameters . Fifty-two patients undergoing coronary artery bypass on cardiopulmonary bypass were divided randomly into 3 groups : the first group received 100 microg x kg ( -1 ) x min ( -1 ) propofol , the other groups received one minimum alveolar concentration of sevoflurane or isoflurane for anesthesia maintenance . Middle cerebral arterial blood flow velocities were measured by transcranial Doppler , and hemodynamics were measured by the thermodilution technique . Middle cerebral arterial blood flow velocities decreased significantly after administration of isoflurane and propofol , but there was no significant difference between the groups . After weaning from cardiopulmonary bypass , cerebral blood flow increased and came close to the value after induction in all groups . The pulsatility index and resistivity index increased significantly only after the propofol infusion , but there was no significant difference between the groups .
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Intervention_Pharmacological
propofol
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Intervention_Pharmacological
isoflurane
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Intervention_Pharmacological
sevoflurane
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Intervention_Pharmacological
propofol
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Intervention_Pharmacological
sevoflurane
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Intervention_Pharmacological
isoflurane
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Intervention_Pharmacological
anesthesia maintenance
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Outcome_Physical
Middle cerebral arterial blood flow velocity and hemodynamics
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Outcome_Physical
middle cerebral arterial blood flow velocity
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Outcome_Physical
Middle cerebral arterial blood flow velocities
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Outcome_Physical
hemodynamics
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Outcome_Physical
Middle cerebral arterial blood flow velocities
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Outcome_Physical
cerebral blood flow increased
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Outcome_Physical
pulsatility index and resistivity index
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Participant_Condition
open heart surgery
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Participant_Condition
Fifty-two patients undergoing coronary artery bypass on cardiopulmonary bypass