85381
document
Early versus late replacement of autotransfused blood in elective spinal surgery . A prospective randomized study . The use of autologous blood is a well established and extremely popular technique to decrease the necessity for homologous transfusions and the attendant risks of hepatitis , HIV , and HTLV -- I/II infections . The most beneficial timing for autologous reinfusion of predonated blood remains unknown . The present study was undertaken to determine the optimal timing of autologous blood reinfusion in elective spinal surgery . Fifty-seven patients were prospectively individually randomly allocated into early versus delayed reinfusion groups prior to undergoing elective spinal surgery by a single surgeon . Three surgical subgroups were entered into the study : anterior/posterior ( A/P ) spinal fusion patients , posterior thoracolumbar scoliosis fusion patients ( PSF ) , and degenerative posterior lumbar fusion patients ( LF ) . Randomization was successful in that three was no significant difference in male to female ratio , age , preoperative hemoglobin , or number of units predonated between the early and delayed reinfusion groups . Likewise , there was no significant difference in the details of the operative procedure when compared as a group for the early versus delayed reinfusion groups . A significant increase in the postoperative day # 1 , 2 and 3 hemoglobin was seen in the early reinfusion group , while there was no significant difference seen in the postoperative day # 7 hemoglobin between the early versus delayed reinfusion group . There was no effect of surgical grouping on these significant comparisons . Earlier patient mobilization was also seen in the early reinfusion groups for the A/P and PSF groups . There was no difference in patients ' subjective evaluation of satisfaction and discomfort between the early or delayed reinfusion groups as determined by blinded interview on days 1 , 3 , 5 , and 7 postoperatively . ( ABSTRACT TRUNCATED AT 250 WORDS )
85382
Intervention_Pharmacological
Early
85383
Intervention_Physical
late replacement
85384
Intervention_Pharmacological
autotransfused blood
85385
Intervention_Surgical
spinal surgery
85386
Intervention_Pharmacological
autologous blood
85387
Intervention_Pharmacological
autologous
85388
Intervention_Pharmacological
autologous blood reinfusion
85389
Intervention_Surgical
spinal surgery
85390
Intervention_Pharmacological
early
85391
Intervention_Physical
delayed reinfusion groups
85392
Intervention_Surgical
elective spinal surgery
85393
Intervention_Pharmacological
early
85394
Intervention_Physical
delayed reinfusion
85395
Intervention_Pharmacological
early reinfusion group
85396
Intervention_Pharmacological
early
85397
Intervention_Physical
delayed reinfusion
85398
Intervention_Pharmacological
early reinfusion
85399
Outcome_Physical
day # 1 , 2 and 3 hemoglobin
85400
Outcome_Other
patient mobilization
85401
Participant_Condition
elective spinal surgery .
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Participant_Condition
undergoing elective spinal surgery
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Participant_Condition
anterior/posterior ( A/P ) spinal fusion patients , posterior thoracolumbar scoliosis fusion patients ( PSF ) , and degenerative posterior lumbar fusion patients ( LF )