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document
Utilization of health care services by patients with chronic obstructive pulmonary disease . In order to identify healthcare resource use patterns associated with chronic obstructive pulmonary disease ( COPD ) , resource utilization ( RU ) data collection was integrated into a randomized , double-blind placebo-controlled study of Viozan ( sibenadet HCl ) . This study enrolled patients with symptomatic , smoking-related COPD , randomized to receive sibenadet or placebo for a 52-week treatment period . A questionnaire establishing typical pre-trial , COPD-related RU was completed by each patient . Subsequent data were collected by means of an Interactive Voice Response System ( IVRS ) at 30-day intervals ( 14 time points ) during the study and in the follow-up period . The IVRS system facilitated data collection and minimized inconvenience to the patient . Compliance with the requirement to record details of the healthcare services during the year-long study was high . No overall trend for lower RU was associated with sibenadet therapy , which correlates with the lack of sustained clinical effect seen in studies conducted concurrently . These data do , however , provide valuable information on RU associated with COPD and insights into adjustments associated with changes in disease course . Physicians were seen to be the most common source of care for patients with COPD and more of the patients with severe COPD ( stage III ) than mild ( stage I ) were seen to utilize the most expensive resources ( e.g . inpatient hospital care ) . For those patients who experienced an exacerbation during the trial ( irrespective of treatment group ) , resource use was increased during the periods when an exacerbation was reported when compared with the periods before or after an exacerbation . The proportion of cases attending the physician doubled and with a trip to the Emergency Room ( ER ) increased approximately ninefold during the reporting period in which the exacerbation occurred compared with the previous month . This study has shown that use of an IVRS , even in elderly patients , is an effective means of gathering RU data over long periods . The study findings suggest that the advent of effective therapeutic interventions , particularly any with the ability to minimize exacerbations and limit disease progression , could impact on the health care services used and potentially reduce associated costs .
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
sibenadet
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Intervention_Control
placebo
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Intervention_Other
Interactive Voice Response System
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Outcome_Other
healthcare resource use patterns
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Outcome_Physical
questionnaire establishing typical pre-trial , COPD-related RU
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Outcome_Other
Interactive Voice Response System ( IVRS )
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Outcome_Physical
RU
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Outcome_Other
inpatient hospital care
11847
Outcome_Other
resource use
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Outcome_Other
proportion of cases attending the physician doubled and with a trip to the Emergency Room ( ER )
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Participant_Condition
chronic obstructive pulmonary disease
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Participant_Condition
chronic obstructive pulmonary disease
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Participant_Condition
COPD
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Participant_Condition
symptomatic , smoking-related COPD
11853
Participant_Condition
severe COPD ( stage III )
11854
Participant_Condition
mild ( stage I )
11855
Participant_Age
elderly