36809
document
Smoking cessation with smokeless tobacco and group therapy : an open , randomized , controlled trial . Smokeless tobacco might be effective as an adjunct for smoking cessation . We evaluated the efficacy of smokeless tobacco and group support for smoking cessation in an open , randomized study that compared smokeless tobacco plus group support versus group support only . The study enrolled 263 healthy smokers ( M ( age ) = 49 years ) who smoked a mean of 24 cigarettes/day , with a mean of 31 pack-years . Smokeless tobacco was provided for 7 weeks ( or up to 12 ) , combined with eight group support visits provided by nurses . The control group received group support only . Smoking cessation rates were statistically significantly better in the smokeless tobacco group than in the control group during the first 7 weeks . Point-prevalence abstinence rates at 7 weeks were 36.4 % versus 20.8 % ( OR = 2.52 , p = .001 ) , respectively ; and continuous abstinence rates from weeks 4 to 7 were 31.5 % versus 19.2 % ( OR = 1.94 , p = .023 ) , respectively . The primary outcomes ( i.e. , 6-month point prevalence ) were 23.1 % versus 20.8 % , respectively ( OR = 1.31 , ns ) . Smokeless tobacco was relatively well tolerated , although 15 subjects ( 11.2 % ) stopped use due to adverse events . A total of 25 subjects ( 17.5 % ) were still using smokeless tobacco after 6 months . This trial demonstrated short-term efficacy of smokeless tobacco in combination with group support for smoking cessation but no long-term efficacy .
36810
Intervention_Pharmacological
smokeless tobacco
36811
Intervention_Psychological
group therapy
36812
Intervention_Pharmacological
Smokeless tobacco
36813
Intervention_Pharmacological
smokeless tobacco
36814
Intervention_Educational
group support
36815
Intervention_Pharmacological
smokeless tobacco
36816
Intervention_Educational
group support
36817
Intervention_Control
group support only
36818
Intervention_Pharmacological
Smokeless tobacco
36819
Intervention_Educational
group support visits provided by nurses .
36820
Intervention_Control
control
36821
Intervention_Control
group support only
36822
Intervention_Pharmacological
Smokeless tobacco
36823
Intervention_Pharmacological
smokeless tobacco
36824
Outcome_Mental
Smoking cessation
36825
Outcome_Mental
smoking cessation
36826
Outcome_Mental
smoking cessation
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Outcome_Mental
Smoking cessation rates
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Outcome_Mental
Point-prevalence abstinence rates
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Outcome_Mental
continuous abstinence rates
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Outcome_Mental
6-month point prevalence
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Outcome_Other
tolerated
36832
Outcome_Adverse-effects
adverse events .
36833
Outcome_Other
short-term efficacy of smokeless tobacco
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Outcome_Other
long-term efficacy .
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Participant_Sample-size
263
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Participant_Condition
healthy smokers
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Participant_Age
49
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Participant_Condition
who smoked a mean of 24 cigarettes/day , with a mean of 31 pack-years