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document
[ Postoperative analgesia : peridural morphine versus sublingual buprenorphine . Comparative clinical study ] . The authors herein present their personal series on the clinical evaluation of the analgesic efficacy of 2 opiodes , peridural morphine hydrochloride ( 0.5 mg/kg ) administered to group A patients , and sublingual buprenorphine ( 0.4 mg ) administered to group B patients in the management of post-operative pain in major abdominal surgery . The study was conducted on 44 patients , both male and female , classified as ASA II and III . Statistical analysis of cardiovascular parameters ( BP and cardiac frequency ) , respiratory frequency and pain score showed an overlapping progression among the two groups . Spontaneous pain decreased significantly to zero at T6 ( p < 0.001 ) . However , the necessity to administer buprenorphine more frequently after the sixth hour and the consequent increase in side effects , lead us to believe that the method used for group A patients is more advantageous .
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Intervention_Pharmacological
peridural morphine
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Intervention_Pharmacological
sublingual buprenorphine .
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Intervention_Pharmacological
peridural morphine hydrochloride ( 0.5 mg/kg )
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Intervention_Pharmacological
sublingual buprenorphine ( 0.4 mg )
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Intervention_Pharmacological
buprenorphine
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Outcome_Physical
cardiovascular parameters ( BP and cardiac frequency )
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Outcome_Physical
respiratory frequency
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Outcome_Pain
pain score
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Outcome_Pain
Spontaneous pain
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Outcome_Adverse-effects
side effects
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Participant_Sample-size
44
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Participant_Sex
male
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Participant_Sex
female