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document
[ PLACE REMAXOL AS A HEPATOPROTECTOR IN INTENSIVE THERAPY OF PERVASIVE PERITONITIS ] . UNLABELLED PERPOSE OF RESEARCH : to evaluate the effectiveness of Remaxol in patients with pervasive peritonitis . MATERIALS AND METHODS assessed the effectiveness of a balanced infusion of the drug ( Remaxol ) in the treatment of 44 patients agedfrom 18 to 50 years . Patients were devided into 2 groups by the method of envelopes . All patients received a comprehensive differential therapy : 21 patient 1 group consisting of infusion therapy in the postoperative period received Remaxol at a dose of 800 mg/day for 7 days . RESULTS the comporative assessment of indicators of systemic hemodinamics , oxygen transport , asid base status , glucose , lactose and free radical oxydation . Patients on the first background was used Remaxol have experiensed a more rapid relief of metabolic disorders , endotoxemia and hepatic dysfunction compared with the indices of the 2 group patients . Noted earlier stabilization of rudicators of systemic hemodynamics and oxygen transport . This has reduced the duration of respiratory and vasopressor suppot , early start ofparenteral intreduction in case the power ( p < 0.05 ) . CONCLUSIONS this study shows that use of the drug for the purpose of relief Remaxol hepatic dysfunction and prevention of drug liver toxicity in conditions ofperitonitis , after 48 hours of operation , provides a positive dynamics and stabilization ofparameters of central hemodynamics , contributing to the abolition of vasopressor support , and contributes to the effective utilization of oxygen , while providing antioxidant effect .
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Intervention_Pharmacological
REMAXOL
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Intervention_Pharmacological
Remaxol
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Intervention_Pharmacological
drug ( Remaxol )
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Intervention_Physical
infusion therapy
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Intervention_Pharmacological
Remaxol
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Intervention_Pharmacological
Remaxol
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Intervention_Pharmacological
Remaxol
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Outcome_Physical
indicators of systemic hemodinamics , oxygen transport , asid base status , glucose , lactose and free radical oxydation .
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Outcome_Physical
rapid relief of metabolic disorders , endotoxemia and hepatic dysfunction compared
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Outcome_Physical
systemic hemodynamics and oxygen transport .
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Outcome_Physical
duration of respiratory and vasopressor suppot