77094
document
The treatment of senile dementia associated with cerebrovascular insufficiency : a comparative study of buflomedil and dihydrogenated ergot alkaloids . Seventy-six patients took part in a randomized , comparative study of the efficacy of buflomedil hydrochloride and dihydrogenated ergot alkaloids in the treatment of senile dementia associated with cerebrovascular insufficiency . Efficacy was assessed by the patients ' performance in four psychometric tests . The results showed that a trend in favour of the buflomedil group in three of the tests became statistically significant in the fourth . Both drugs appeared to be safe , causing no marked adverse reactions . In conclusion , buflomedil is as effective or more effective than dihydrogenated ergot alkaloids in the treatment of senile dementia associated with cerebrovascular insufficiency and could prove a valuable addition to long-term therapy if further studies support the trend shown in this study .
77095
Intervention_Pharmacological
buflomedil
77096
Intervention_Pharmacological
dihydrogenated ergot alkaloids
77097
Intervention_Pharmacological
buflomedil hydrochloride
77098
Intervention_Pharmacological
dihydrogenated ergot alkaloids
77099
Outcome_Physical
senile dementia
77100
Outcome_Physical
senile dementia
77101
Outcome_Other
Efficacy
77102
Outcome_Mental
psychometric tests
77103
Outcome_Other
safe
77104
Outcome_Adverse-effects
adverse reactions
77105
Outcome_Physical
senile dementia
77106
Participant_Condition
dihydrogenated