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document
Docosahexaenoic acid-rich fish oil modulates the cerebral hemodynamic response to cognitive tasks in healthy young adults . A number of recent studies have assessed the impact of dietary omega-3 polyunsaturated fatty acids ( n-3 PUFAs ) on behavioral outcomes ; however , very little attention has been given to their impact upon brain function in physiological terms . Sixty-five healthy adults aged 18-29yrs took part in this double-blind , placebo-controlled study assessing the effects of 12 weeks daily dietary supplementation with docosahexaenoic acid-rich fish oil ( 1g , 2g ) or placebo ( olive oil ) . Relative changes in the concentration of oxyhemoglobin and deoxyhemoglobin were assessed in the prefrontal cortex using near-infrared spectroscopy during performance of nine computerized cognitive tasks . Supplementation with both doses of fish oil , in comparison with placebo , resulted in significantly increased concentrations of oxyhemoglobin and total levels of hemoglobin , indicative of increased cerebral blood flow , during the cognitive tasks . Changes in hemodynamic response to tasks were not accompanied by consistent changes in cognitive performance .
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Intervention_Pharmacological
Docosahexaenoic acid-rich fish oil
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
docosahexaenoic acid-rich fish oil
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Intervention_Control
or placebo ( olive oil ) .
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Outcome_Physical
cerebral hemodynamic response
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Outcome_Physical
concentration of oxyhemoglobin and deoxyhemoglobin
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Outcome_Physical
concentrations of oxyhemoglobin and total levels of hemoglobin
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Outcome_Physical
cerebral blood flow
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Outcome_Physical
hemodynamic
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Outcome_Physical
cognitive performance
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Participant_Condition
healthy
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Participant_Age
young adults
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Participant_Sample-size
Sixty-five
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Participant_Condition
healthy
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Participant_Age
adults aged 18-29yrs