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document
Milk production in cows with endotoxin-induced mastitis treated with isotonic or hypertonic sodium chloride solution . Milk production was monitored in 16 cows for 6 milkings after intramammary infusion of 1 mg of endotoxin in a single forequarter . The cows were randomly assigned to 1 of 2 treatment groups ; 8 cows were treated with isotonic saline solution and 8 cows were treated with hypertonic saline solution . Saline solutions were administered IV ( 5 ml/kg of body weight ) 4 hours after infusion of endotoxin . Mean cumulative change in milk yield and interval change in milk yield were greater in cows treated with isotonic saline solution than in cows treated with hypertonic saline solution . Significant differences between treatment groups were not detected .
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Intervention_Pharmacological
endotoxin-induced mastitis
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Intervention_Pharmacological
isotonic or hypertonic sodium chloride solution
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Intervention_Pharmacological
endotoxin
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Intervention_Pharmacological
isotonic saline solution
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Intervention_Pharmacological
hypertonic saline solution
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Intervention_Pharmacological
Saline
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Intervention_Pharmacological
endotoxin
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Intervention_Pharmacological
solution
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Intervention_Pharmacological
hypertonic saline solution
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Outcome_Physical
Milk production
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Outcome_Physical
Milk production
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Outcome_Physical
Mean cumulative change in milk yield and interval change in milk yield
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Participant_Condition
endotoxin-induced mastitis
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Participant_Sample-size
16
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Participant_Sample-size
8
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Participant_Sample-size
8
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Participant_Sex
cows