75391
document
Nitrous oxide does not increase the incidence of nausea and vomiting after isoflurane anesthesia . A total of 110 patients undergoing elective abdominal hysterectomy were anesthetized in random order with either isoflurane in nitrous oxide and oxygen or isoflurane in air and oxygen . Fentanyl was used as an adjunct to isoflurane in all patients , 0.05 mg every 45 min . No difference was found between the two anesthetic techniques in the incidence of nausea , vomiting , or both during the first 24 hr after operation . The overall incidence was 62 and 67 % for air-O2 and N2O-O2 groups , respectively . Patients who had had nausea or vomiting after previous anesthetics had nausea or vomiting significantly more frequently than patients who did not . It is concluded that nitrous oxide does not contribute to the occurrence of nausea or vomiting after isoflurane anesthesia for gynecologic laparotomies .
75392
Intervention_Pharmacological
Nitrous oxide
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Intervention_Pharmacological
isoflurane in nitrous oxide and oxygen or isoflurane in air and oxygen
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Intervention_Pharmacological
Fentanyl
75395
Intervention_Pharmacological
nitrous oxide
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Outcome_Adverse-effects
incidence of nausea , vomiting , or both
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Outcome_Adverse-effects
incidence
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Outcome_Adverse-effects
nausea or vomiting
75399
Outcome_Adverse-effects
nausea or vomiting
75400
Outcome_Adverse-effects
nausea or vomiting
75401
Participant_Condition
nausea and vomiting after isoflurane anesthesia
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Participant_Sample-size
110 patients
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Participant_Condition
undergoing elective abdominal hysterectomy were anesthetized in random order
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Participant_Condition
all patients