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document
[ Long term observation in effects of potassium and calcium supplementation on arterial blood pressure and sodium metabolism in adolescents with higher blood pressure ] . OBJECTIVE To investigate the effects of potassium and calcium supplementation in table salt on reduction of arterial blood pressure and sodium metabolism in adolescents with higher blood pressure . METHODS A single blind placebo-controlled trial was carried out for two years in 220 adolescents with higher blood pressure , aged 18 - 22 years , who were randomly divided into supplementary group ( n = 110 ) and control group ( n = 110 ) . Each of the subjects in the supplementary group and their family members was given 10 mmol of potassium and 10 mmol of calcium mixed in their table salt daily for 24 months . RESULTS Night urinary sodium and potassium excretion increased ( urinary Na ( + ) , P < 0.05 ; urinary K ( + ) , P < 0.01 ) and blood pressure lowered by 5.3 mm Hg/1.8 mm Hg in average from the baseline in the supplementary group two years after potassium and calcium supplementation , as compared with that in the control group increased by ( 1.3/1.7 ) mm Hg . CONCLUSIONS Adequate supplement of potassium and calcium in daily table salt intake was an effective way to prevent form hypertension and could promote their urinary sodium excretion and reduction of arterial blood pressure in adolescents with higher blood pressure .
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Intervention_Pharmacological
potassium and calcium supplementation
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Intervention_Pharmacological
potassium and calcium supplementation
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
10 mmol of potassium and 10 mmol of calcium mixed in their table salt
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Intervention_Pharmacological
potassium and calcium supplementation
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Intervention_Pharmacological
supplement of potassium and calcium
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Outcome_Physical
arterial blood pressure
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Outcome_Physical
sodium metabolism
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Outcome_Physical
arterial blood pressure
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Outcome_Physical
sodium metabolism
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Outcome_Physical
Night urinary sodium and potassium excretion
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Outcome_Physical
blood pressure lowered
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Outcome_Physical
form hypertension
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Outcome_Physical
urinary sodium excretion
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Outcome_Physical
reduction of arterial blood pressure
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Participant_Condition
adolescents with higher blood pressure ]