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document
Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders . The Studies to Advance Autism Research and Treatment Network conducted a randomized trial with citalopram in children with Pervasive developmental disorders ( PDDs ) . We present the rationale , design and sample characteristics of the citalopram trial . Subjects ( 128 boys , 21 girls ) had a mean age of 9.3 ( ±3.12 ) years ; 132 ( 88.6 % ) were diagnosed with autistic disorder ( 4.7 % with Asperger 's Disorder ; 6.7 % with PDD-not otherwise specified ) . Less than half of the subjects were intellectually disabled ; 117 ( 78.5 % ) were rated Moderate or Marked on the Clinical Global Impression for Severity . Study measures were similar to previous Research Units on Pediatric Psychopharmacology trials . Subjects in this trial were slightly older and more likely to have complaints of repetitive behavior than participants in RUPP trials .
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Intervention_Pharmacological
citalopram
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Intervention_Pharmacological
citalopram
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Intervention_Pharmacological
citalopram
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Outcome_Physical
were
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Outcome_Mental
intellectually disabled
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Outcome_Mental
repetitive behavior
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Participant_Age
children
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Participant_Condition
pervasive developmental disorders
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Participant_Condition
Pervasive developmental disorders ( PDDs ) .