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document
[ Statins in the treatment of patients with arterial occlusive disease of the lower extremities ] . In patients with advanced atherosclerosis manifested by arterial occlusion in the lower extremities without a baseline blood lipid disorder statin treatment caused improvement of the efficiency , i.e . prolongation of the claudication interval , while in a comparable control group without statins the efficiency deteriorated further . In patients with arterial occlusion of the lower extremities with baseline dyslipidaemia statin treatment proved protective , i.e . at least it retarded the patients ' complaints . The authors recorded improvement of the prooxidation state which followed after the dynamics of improvement of the impaired blood lipid spectrum . The results admit a possible part played by the pleiotropic effect of statins .
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Intervention_Pharmacological
Statins
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Intervention_Pharmacological
statin
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Intervention_Pharmacological
statin
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Outcome_Other
efficiency , i.e .
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Outcome_Physical
prolongation of the claudication interval
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Outcome_Physical
protective
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Outcome_Physical
at least it retarded the patients ' complaints
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Outcome_Physical
the prooxidation state
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Outcome_Physical
blood lipid spectrum