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document
Moderate sodium restriction , angiotensin converting enzyme inhibition , and thiazide diuretic in the management of essential hypertension . Dietary sodium restriction alone is effective in lowering blood pressure in some , but not all , patients with essential hypertension . Homeostatic mechanisms , including activation of the renin-aldosterone system , may counteract the effects of sodium restriction . Angiotensin converting enzyme ( ACE ) inhibitors are also effective as sole therapy in many patients with essential hypertension , but may be less effective in those with low-renin hypertension . The combination of dietary sodium restriction with blockade of the renin system by an ACE inhibitor is a particularly effective way to improve blood pressure control . Addition of a thiazide diuretic will reduce pressure further .
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Intervention_Physical
Moderate sodium restriction
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Intervention_Pharmacological
angiotensin converting enzyme inhibition
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Intervention_Pharmacological
thiazide diuretic
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Intervention_Pharmacological
Dietary sodium restriction
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Intervention_Pharmacological
sodium
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Intervention_Pharmacological
Angiotensin converting enzyme ( ACE ) inhibitors
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Intervention_Pharmacological
combination of
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Intervention_Physical
dietary sodium restriction
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Intervention_Pharmacological
ACE inhibitor
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Intervention_Pharmacological
thiazide diuretic
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Outcome_Physical
blood pressure
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Outcome_Other
effective
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Outcome_Physical
blood pressure control .
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Outcome_Physical
pressure
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Participant_Condition
essential hypertension