15673
document
Clinical and radiographic evaluation of guided tissue regeneration in the treatment of class II furcation defects . A randomized clinical trial . PURPOSE To evaluate the treatment outcomes after guided tissue regeneration ( GTR ) with a bioabsorbable membrane in Class II furcation defects in mandibular molars . The open flap debridement ( OFD ) was used as the control . METHODS Nine patients , with two comparable Class II furcation defects were included in the study . After initial preparation , the defects were randomly assigned in each patient to either GTR-group or OFD-group . Clinical parameters and standardized radiographs were obtained at baseline and 6 months after the surgeries . The radiographs were analyzed by subtraction radiography . RESULTS Comparing baseline to 6-month results , both groups showed statistically significant probing depth reduction ( PD ) , horizontal clinical attachment level ( CAL-h ) gain , and increase in gingival recession ( GR ) . The vertical clinical attachment level ( CAL-v ) gain was statistically significant only for the OFD-group . Comparing the two treatments , no statistically significant differences were found in PD reduction ( GTR : 1.67 mm ; OFD : 2.51 mm , P = 0.26 ) , CAL-v gain ( GTR : 0.62 mm ; OFD : 1.16 mm , P= 0.37 ) , and GR increase ( GTR : 1.04 mm ; OFD : 1.24 mm , P = 0.31 ) . GTR provided complete closure of the furcation defect in two sites and superior horizontal clinical attachment level gain ( GTR : 2.27 mm ; OFD : 1.01 mm , P = 0.05 ) . Subtraction radiography showed significant difference in bone height change between GTR-group and OFD-group ( -0.14 mm and 0.86 mm , respectively ; P = 0.028 ) at 6 months .
15674
Intervention_Physical
guided tissue regeneration ( GTR )
15675
Intervention_Physical
GTR-group
15676
Intervention_Physical
OFD-group
15677
Intervention_Physical
radiographs
15678
Intervention_Physical
GTR
15679
Outcome_Physical
probing depth reduction ( PD )
15680
Outcome_Physical
horizontal clinical attachment level ( CAL-h ) gain
15681
Outcome_Physical
increase in gingival recession ( GR )
15682
Outcome_Physical
vertical clinical attachment level ( CAL-v ) gain
15683
Outcome_Physical
PD reduction
15684
Outcome_Physical
CAL-v gain
15685
Outcome_Physical
GR increase
15686
Outcome_Physical
closure of the furcation defect
15687
Outcome_Physical
superior horizontal clinical attachment level gain
15688
Participant_Condition
class II furcation defects
15689
Participant_Sample-size
Nine
15690
Participant_Condition
Class II furcation defects
15691
Participant_Condition
GTR-group or OFD-group