41218
document
Enhancing the working memory of stroke patients using tDCS . OBJECTIVES We investigated whether anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex affected the working memory performance of patients after a stroke . DESIGN Ten patients ( mean age 47.7 yrs ) with cognitive deficits after a first-ever stroke participated in this single-blind , crossover , and sham-controlled experiment . Each patient was randomly assigned to undergo two transcranial direct current stimulation sessions : anodal dorsolateral prefrontal cortex and sham stimulation within 48 hrs of a washout period . All participants performed a two-back working memory task before and after the administration of the transcranial direct current stimulation . Accuracy ( correction rate ) , recognition accuracy ( correction rate-commission error rate ) , and response time were measured during each experiment . RESULTS Repeated-measures analysis of variance indicated a significant interaction effect of transcranial direct current stimulation type and time on the recognition accuracy . Post hoc analyses revealed a significant difference between prestimulation and poststimulation in the anodal stimulation group but not in the sham stimulation group . Regarding the accuracy , the paired t test indicated significant improvement only after anodal transcranial direct current stimulation without a significant interaction effect between the two transcranial direct current stimulation types . The response time was not significantly different in the anodal and sham stimulation groups . CONCLUSION Our results demonstrated that anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex was associated with enhanced working memory performance as indexed by the recognition accuracy in patients after a stroke .
41219
Intervention_Physical
tDCS
41220
Intervention_Physical
transcranial direct current stimulation
41221
Intervention_Control
sham-controlled
41222
Intervention_Physical
transcranial direct current stimulation
41223
Intervention_Physical
transcranial direct current stimulation
41224
Intervention_Physical
transcranial direct current stimulation
41225
Outcome_Mental
working memory
41226
Outcome_Mental
working memory performance
41227
Outcome_Mental
two-back working memory task
41228
Outcome_Mental
Accuracy ( correction rate )
41229
Outcome_Mental
recognition accuracy ( correction rate-commission error rate )
41230
Outcome_Mental
response time
41231
Outcome_Mental
recognition accuracy
41232
Outcome_Other
accuracy
41233
Outcome_Other
response time
41234
Outcome_Mental
working memory performance
41235
Participant_Condition
stroke patients
41236
Participant_Condition
stroke
41237
Participant_Sample-size
Ten patients
41238
Participant_Age
mean age 47.7 yrs
41239
Participant_Condition
stroke