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document
A carbohydrate meal attenuates the forearm vasoconstrictor response to lower body subatmospheric pressure in healthy young adults . The cardiovascular ( CV ) responses to meal ingestion and orthostasis are well established . The effect of meal ingestion and meal composition on the CV responses to orthostasis are unknown . The effect of high carbohydrate ( HC ) and high fat ( HF ) meal ingestion on the CV responses to simulated orthostatic stress ( using graded lower body subatmospheric pressure ( LBSP ) ) was assessed in nine healthy young volunteers . Cardiac output ( CO ) , forearm blood flow ( FABF ) heart rate ( HR ) and blood pressure ( BP ) were measured before and during LBSP while fasted and after eating HC and HF meals . Ingestion of both meals led to an increase in CO and HR . Both meals resulted in a fall in total peripheral resistance but only HC led to a significant fall in BP ( p < 0.05 ) . HF had no effect on the CV responses to LBSP , whereas HC resulted in attenuated FABF and forearm vascular resistance responses ( p < 0.05 ) . Thus , ingestion of an HC meal significantly attenuates the forearm vascular response to orthostatic stress and the hypotensive effect of orthostasis is additive to that occurring after an HC meal .
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Intervention_Pharmacological
carbohydrate meal
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Intervention_Pharmacological
meal ingestion
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Intervention_Pharmacological
high carbohydrate ( HC )
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Intervention_Pharmacological
high fat ( HF
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Intervention_Pharmacological
HC
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Intervention_Pharmacological
HF
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Intervention_Pharmacological
HC meal
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Outcome_Physical
Cardiac output ( CO ) , forearm blood flow ( FABF ) heart rate ( HR )
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Outcome_Physical
blood pressure ( BP )
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Outcome_Physical
CO
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Outcome_Physical
HR
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Outcome_Physical
total peripheral resistance
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Outcome_Physical
BP
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Outcome_Physical
LBSP
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Outcome_Physical
attenuated FABF and forearm vascular resistance responses
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Participant_Age
adults
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Participant_Sample-size
nine