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document
Comparison of ketanserin and pindolol in hypertension . The antihypertensive effects of ketanserin ( 40 mg twice daily ) and pindolol ( 5 mg twice daily ) as monotherapy were compared in a crossover , double-blind trial in 17 patients with essential hypertension . Both ketanserin and pindolol decreased supine systolic and diastolic blood pressure significantly ( P less than 0.01 for systolic and P less than 0.001 for diastolic ) when evaluated at the end of the 2-month treatment periods . There was no significant difference between the two drugs . No significant changes in heart rate were observed on either drug . Both drugs were well tolerated .
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Intervention_Pharmacological
ketanserin
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Intervention_Pharmacological
pindolol
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Intervention_Pharmacological
ketanserin
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Intervention_Pharmacological
pindolol
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Intervention_Pharmacological
ketanserin
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Intervention_Pharmacological
pindolol
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Outcome_Physical
supine systolic and diastolic blood pressure
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Outcome_Physical
systolic and P
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Outcome_Physical
heart rate
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Participant_Condition
hypertension .
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Participant_Sample-size
17