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document
TRANSCONJUNCTIVAL NONVITRECTOMIZING VITREOUS SURGERY VERSUS 25-GAUGE VITRECTOMY IN PATIENTS WITH EPIRETINAL MEMBRANE : A Prospective Randomized Study . PURPOSE To compare the clinical outcomes and the rate of complications of 27-gauge transconjunctival nonvitrectomizing vitreous surgery ( NVS ) and of 25-gauge transconjunctival sutureless vitrectomy surgery for idiopathic epiretinal membrane removal . METHODS In this prospective randomized study , 83 phakic eyes of 83 consecutive patients with an idiopathic epiretinal membrane were randomized to receive 27-gauge NVS ( NVS-group ) or 25-gauge vitrectomy ( Standard-group ) . Main outcome measures were best-corrected visual acuity , central retinal thickness , nuclear density units ' changes , and rate of complications . RESULTS Thirty-nine eyes of the Standard-group and 40 of the NVS-group were considered in final analysis . Mean best-corrected visual acuity improved significantly in both groups , with a significant better result at 12 months in NVS-group ( P = 0.039 ; t-test ) . Central retinal thickness decreased significantly in both groups ( P < 0.001 , Tukey test ) , without significant difference between the two groups at any time point . At 12 months , nuclear density increased significantly in the Standard-group ( analysis of variance , P < 0.001 ) , and it did not change in the NVS-group ( analysis of variance , P = 0.537 ) . Epiretinal membrane recurred in 5.1 % of eyes in the Standard-group and in 7.5 % of eyes in the NVS-group ( Fisher 's exact test , P = 1.000 ) . CONCLUSION The 27-gauge NVS is an effective surgical procedure in eyes with epiretinal membrane and it induces less progression of nuclear sclerosis than 25-gauge vitrectomy .
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Intervention_Surgical
TRANSCONJUNCTIVAL NONVITRECTOMIZING VITREOUS SURGERY VERSUS 25-GAUGE VITRECTOMY
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Intervention_Surgical
27-gauge transconjunctival nonvitrectomizing vitreous surgery ( NVS )
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Intervention_Surgical
25-gauge transconjunctival sutureless vitrectomy surgery
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Intervention_Surgical
27-gauge NVS ( NVS-group )
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Intervention_Surgical
25-gauge vitrectomy
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Intervention_Surgical
NVS-group
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Intervention_Surgical
27-gauge NVS
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Intervention_Surgical
25-gauge vitrectomy .
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Outcome_Physical
Mean best-corrected visual acuity
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Outcome_Physical
Central retinal thickness
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Outcome_Physical
nuclear density
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Outcome_Physical
Epiretinal membrane
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Participant_Condition
EPIRETINAL MEMBRANE
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Participant_Condition
surgery for idiopathic epiretinal membrane removal
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Participant_Sample-size
83
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Participant_Condition
idiopathic epiretinal membrane
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Participant_Condition
vitrectomy
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Participant_Sample-size
Thirty-nine
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Participant_Sample-size
40