87903
document
Intraumbilical vein injection of prostaglandin F2 alpha in retained placenta . A randomized protocol was used to study the effect of intraumbilical prostaglandin F2 alpha ( Hembate , Upjohn ) and oxytocin injection in women with retained placenta . Prostaglandin F2 alpha , 20 mg , diluted to 20 ml in normal saline solution ( 10 women , group 1 ) , 30 IU of oxytocin , diluted to 20 ml in normal saline solution ( 11 women , group 2 ) , or 20 ml of normal saline solution alone ( 7 women , group 3 ) , were injected into the umbilical vein 1 h after delivery . Nine women ( group 4 , controls ) underwent manual removal of the retained placenta . In group 1 , placental expulsion occurred in all patients and the duration of the placental expulsion after prostaglandin F2 alpha injection was 6.8 +/- 1.36 ( mean +/- SE ) min : in group 2 , six placental expulsions occurred after 13.3 +/- 1.97 min ( mean +/- SE ) ; and in group 3 , no effect was recorded after intraumbilical saline injection . We suggest that intraumbilical vein injection of prostaglandin F2 alpha might be a beneficial , non-surgical method for treating retained placenta . Oxytocin might reduce the incidence of manual lysis of the placenta and achieve partial success .
87904
Intervention_Pharmacological
prostaglandin F2 alpha
87905
Intervention_Pharmacological
intraumbilical prostaglandin F2 alpha
87906
Intervention_Pharmacological
Hembate
87907
Intervention_Pharmacological
Upjohn
87908
Intervention_Pharmacological
oxytocin injection
87909
Intervention_Pharmacological
Prostaglandin F2 alpha
87910
Intervention_Pharmacological
diluted to 20 ml in normal saline solution
87911
Intervention_Pharmacological
30 IU of oxytocin
87912
Intervention_Pharmacological
diluted to 20 ml in normal saline solution
87913
Intervention_Pharmacological
20 ml of normal saline solution alone
87914
Intervention_Pharmacological
prostaglandin F2 alpha
87915
Intervention_Pharmacological
prostaglandin F2 alpha
87916
Intervention_Pharmacological
Oxytocin
87917
Outcome_Physical
placental expulsion
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Outcome_Physical
duration of the placental expulsion after prostaglandin F2 alpha injection
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Outcome_Physical
placental expulsions
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Outcome_Physical
incidence of manual lysis of the placenta
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Participant_Condition
retained placenta .
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Participant_Sex
women
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Participant_Sample-size
10 women ,
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Participant_Sample-size
11 women
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Participant_Sample-size
7 women
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Participant_Sample-size
Nine
87927
Participant_Sex
women