77299
document
Controlled trial of induction of labor by vaginal suppositories containing prostaglandin E2 . A group of 84 women at 39-43 weeks of pregnancy were randomly allocated to a blind trial of induction of labor with vaginal suppositories containing inert material or either 0.2 mg or 0.4 mg of prostaglandin E2 . The suppositories were self-administered every two hours during waking hours on two successive days until labor started or 15 had been used . Side-effects were absent . Labor was established within 48 hr of insertion of the first suppository in 9.3 % of control patients , 65.4 % of those treated with 0.2 mg PGE2 and 85.7 % of those treated with 0.4 mg PGE2 . The mean Apgar scores in the three groups were the same . The mean total dose of PGE2 were 2.0 mg ( 0.2 mg group ) and 2.3 mg ( 0.4 mg group ) . It is concluded that vaginal PGE2 is an effective and acceptable method of inducing labor at term .
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Intervention_Pharmacological
suppositories
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Intervention_Pharmacological
prostaglandin E2
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Intervention_Pharmacological
suppositories
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Intervention_Control
inert material
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Intervention_Pharmacological
prostaglandin E2
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Intervention_Pharmacological
PGE2
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Intervention_Pharmacological
PGE2
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Intervention_Pharmacological
PGE2
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Intervention_Pharmacological
PGE2
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Outcome_Physical
labor
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Outcome_Physical
labor
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Outcome_Physical
Labor was established
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Outcome_Physical
mean Apgar scores
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Outcome_Physical
mean total dose of PGE2
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Outcome_Physical
vaginal PGE2
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Outcome_Physical
method of inducing labor at term .
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Participant_Condition
84 women at 39-43 weeks of pregnancy