51356
document
Topical PUVA , etretinate , and combined PUVA and etretinate for palmoplantar pustulosis : comparison of therapeutic efficacy and the influences of tonsillar and dental focal infections . Twenty patients with palmoplantar pustulosis ( PPP ) were treated with topical PUVA , oral etretinate ( Re ) , or combined PUVA and etretinate ( Re-PUVA ) . Re and Re-PUVA treated sites improved and/or cleared more rapidly than PUVA treated sites . Complete clearance was observed in six of ten sites treated with Re-PUVA , two of ten with Re , and one of ten sites with PUVA within 12 weeks . UVA-control sites failed to be cleared within 12 weeks . Remission periods after stopping the treatment were 1.5 +/- 0.5 weeks ( n = 2 ) with Re , 10.5 +/- 11.4 weeks ( n = 6 ) with Re-PUVA , and one year ( n = 1 ) with PUVA . These results overall suggested that Re-PUVA is the most effective treatment for PPP . Tonsillar focal infection ( TFI ) and dental focal infection ( DFI ) were found in 6/20 and 17/20 patients , respectively . However , the presence of focal infection ( FI ) , TFI and/or DFI , did not appear to interfere with the therapeutic activities of Re and/or PUVA , because the complete clearance rates and remission periods in FI ( + ) patients were comparable with those in FI ( - ) patients .
51357
Intervention_Pharmacological
Topical PUVA
51358
Intervention_Pharmacological
etretinate
51359
Intervention_Pharmacological
combined PUVA and etretinate
51360
Intervention_Pharmacological
topical PUVA
51361
Intervention_Pharmacological
oral etretinate ( Re )
51362
Intervention_Pharmacological
combined PUVA and etretinate ( Re-PUVA )
51363
Outcome_Other
therapeutic efficacy
51364
Outcome_Physical
tonsillar
51365
Outcome_Physical
sites improved and/or cleared
51366
Outcome_Other
Complete clearance
51367
Outcome_Other
cleared
51368
Outcome_Physical
Remission periods
51369
Outcome_Physical
Tonsillar focal infection ( TFI )
51370
Outcome_Physical
dental focal infection ( DFI )
51371
Outcome_Physical
focal infection ( FI )
51372
Outcome_Physical
TFI
51373
Outcome_Physical
DFI
51374
Outcome_Physical
complete clearance rates
51375
Outcome_Physical
remission periods
51376
Participant_Sample-size
Twenty
51377
Participant_Condition
palmoplantar pustulosis ( PPP )