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document
Injection pain with propofol . Reduction with aspiration of blood . A randomised , controlled , single-blind study was performed on 100 patients to investigate a new method of reducing pain on propofol injection . Aspiration of 2 ml of the patient 's blood into a syringe of propofol immediately before injection was compared with the addition of lignocaine 20 mg or normal saline 2 ml to the propofol before injection . The addition of blood was significantly more effective in reducing pain on injection than the addition of saline ( p < 0.001 ) , but was not significantly more effective than the addition of lignocaine .
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Intervention_Pharmacological
propofol .
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Intervention_Pharmacological
propofol
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Intervention_Pharmacological
propofol
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Intervention_Pharmacological
lignocaine 20 mg
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Intervention_Control
normal saline
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Intervention_Pharmacological
2 ml to the propofol before injection
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Outcome_Pain
Injection pain
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Outcome_Pain
pain
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Outcome_Pain
reducing pain on injection
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Outcome_Other
effective
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Participant_Sample-size
100