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document
Double-blind comparison of ketazolam , diazepam and placebo in once-a-day vs t.i.d . dosing . Comparison of ketazolam given once-a-day with diazepam given three times a day and placebo given either once or 3 times a day in 101 anxious outpatients showed ketazolam to be significantly better than placebo in alleviating the symptoms of anxiety and , on several measures of efficacy , better than diazepam as well . Significantly fewer patients on ketazolam dropped out of the study due to ineffective medication than on the other 3 treatments . The incidence of side effects was lowest in the ketazolam group . Of particular note , drowsiness was reported twice as often by diazepam patients as by ketazolam patients .
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Intervention_Pharmacological
ketazolam
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Intervention_Pharmacological
diazepam
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Intervention_Control
placebo
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Intervention_Pharmacological
ketazolam
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Intervention_Pharmacological
diazepam
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Intervention_Control
placebo
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Intervention_Pharmacological
ketazolam
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Intervention_Pharmacological
diazepam
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Intervention_Pharmacological
ketazolam
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Outcome_Adverse-effects
incidence of side effects was lowest
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Outcome_Adverse-effects
drowsiness
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Participant_Sample-size
101
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Participant_Condition
anxious outpatients