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document
Cone biopsy : has endocervical sampling a role ? OBJECTIVE To investigate the sensitivity , specificity and predictive value of endocervical sampling in women with abnormal cervical smears . DESIGN A randomized study of two methods of endocervical sampling . SETTING Colposcopy clinic at Aberdeen Royal Infirmary . SUBJECTS 100 women with abnormal cervical smears selected for cone biopsy according to current colposcopy criteria . INTERVENTIONS 53 women were randomized to have endocervical sampling with the Kevorkian curette and 47 to have sampling with the Medscand endocervical brush . MAIN OUTCOME MEASURES Cytology and histology results from endocervical sampling compared with cone biopsy histology . RESULTS The overall sensitivity of endocervical sampling was 56 % , with a false negative rate of 44 % and a negative predictive value of 26 % . CONCLUSIONS Endocervical sampling should not influence management when colposcopy is unsatisfactory .
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Intervention_Physical
endocervical sampling
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Intervention_Physical
endocervical sampling
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Intervention_Physical
endocervical sampling
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Intervention_Physical
endocervical sampling with the Kevorkian curette
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Intervention_Physical
sampling with the Medscand endocervical brush
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Intervention_Physical
endocervical sampling
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Intervention_Physical
endocervical sampling
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Intervention_Physical
Endocervical sampling
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Outcome_Other
Cytology and histology results from endocervical sampling
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Outcome_Other
cone biopsy histology
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Outcome_Other
sensitivity of endocervical sampling
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Outcome_Other
false negative rate
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Outcome_Other
negative predictive value
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Participant_Sex
women
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Participant_Condition
abnormal cervical smears .
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Participant_Sample-size
100
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Participant_Sex
women
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Participant_Condition
abnormal cervical smears