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document
Cost-effectiveness of ablation surgery in patients with atrial fibrillation undergoing cardiac surgery . This study was performed to assess the cost-effectiveness of concomitant ablation surgery ( AS ) compared to regular cardiac surgery in atrial fibrillation ( AF ) patients over a one-year follow-up . Cost analysis was performed from a societal perspective alongside a prospective , randomised , double-blinded , multicentre trial . One hundred and fifty patients with documented AF were randomly assigned to undergo cardiac surgery with or without AS . One hundred and thirty-two patients were included in the cost-effectiveness study . All costs ( medical and non-medical ) were measured during follow-up . Costs data were combined with quality adjusted life years ( QALYs ) to obtain the incremental costs per QALY . Total costs of the AS group were significantly higher compared to the regular cardiac surgery group [ cost difference bootstrap : €4,724 ; 95 % uncertainty interval ( UI ) , €2,770-€6,678 ] . The bootstrapped difference in QALYs was not statistically significant ( 0.06 ; 95 % UI : -0.024 to 0.14 ) . The incremental cost-effectiveness ratio is €73,359 per QALY . The acceptability curve showed that , even in the case of a maximum threshold value of €80,000 per QALY gained , the probability of AS being more cost-effective than regular cardiac surgery did not reach beyond 50 % . Concluding that concomitant AS in AF is not cost-effective after a one-year follow-up compared to regular cardiac surgery .
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Intervention_Surgical
ablation surgery
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Intervention_Surgical
ablation surgery ( AS )
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Intervention_Surgical
cardiac surgery
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Intervention_Surgical
randomly assigned to undergo cardiac surgery with or without AS
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Intervention_Surgical
AS
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Outcome_Other
Cost-effectiveness
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Outcome_Other
Cost analysis
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Outcome_Other
All costs ( medical and non-medical )
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Outcome_Other
Costs data
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Outcome_Other
quality adjusted life years
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Outcome_Other
Total costs