5763
document
Work-related stress and early atherosclerosis . The purpose of this study was to examine the link between work-related stress and early atherosclerosis as measured by common carotid artery intima-media thickness and focal lesions in the common carotid artery and bifurcation . Four hundred sixty-seven members of an occupational cohort ( total N = 573 ) were examined via questionnaires and B-mode ultrasound . We used multiple linear and logistic models to regress lesion risk and intima-media thickness on work-related stress scores from a questionnaire administered at an 18-month follow-up examination . In an age-adjusted model , the prevalence of carotid lesions among men scoring in the highest stress quintile was 36 % compared with 21 % among men in the lowest quintile . We also observed an increase in intima-media thickness in the highest quintile relative to the lowest ( difference = 0.048 +/- 0.025 mm ) among men . Among women , stress was not related to the prevalence of lesions or intima-media thickness . These findings suggest that men with greater work-related stress are at increased risk for atherosclerotic disease . Women in this age group may be protected from such effects , or current work-place questionnaires may not accurately assess stress in women .
5764
Intervention_Psychological
questionnaires
5765
Intervention_Physical
B-mode ultrasound
5766
Outcome_Mental
work-related stress scores
5767
Outcome_Physical
prevalence of carotid lesions
5768
Outcome_Physical
intima-media thickness
5769
Outcome_Mental
stress
5770
Outcome_Physical
prevalence of lesions or intima-media thickness
5771
Outcome_Mental
work-related stress
5772
Outcome_Physical
atherosclerotic disease
5773
Participant_Condition
Work-related stress and early atherosclerosis .
5774
Participant_Condition
early atherosclerosis
5775
Participant_Sample-size
Four hundred sixty-seven
5776
Participant_Sample-size
573
5777
Participant_Sex
women ,
5778
Participant_Sex
men
5779
Participant_Condition
work-related stress