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document
Omega-3/omega-6 fatty acids for attention deficit hyperactivity disorder : a randomized placebo-controlled trial in children and adolescents . OBJECTIVE The aim of the study was to assess omega 3/6 fatty acids ( eye q ) in attention deficit hyperactivity disorder ( ADHD ) . METHOD The study included a randomized , 3-month , omega 3/6 placebo-controlled , one-way crossover trial with 75 children and adolescents ( 8-18 years ) , followed by 3 months with omega 3/6 for all . Investigator-rated ADHD Rating Scale-IV and Clinical Global Impression ( CGI ) scale were outcome measures . RESULTS A majority did not respond to omega 3/6 treatment . However , a subgroup of 26 % responded with more than 25 % reduction of ADHD symptoms and a drop of CGI scores to the near-normal range . After 6 months , 47 % of all showed such improvement . Responders tended to have ADHD inattentive subtype and comorbid neurodevelopmental disorders . CONCLUSION A subgroup of children and adolescents with ADHD , characterized by inattention and associated neurodevelopmental disorders , treated with omega 3/6 fatty acids for 6 months responded with meaningful reduction of ADHD symptoms .
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Intervention_Pharmacological
Omega-3/omega-6 fatty acids
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Intervention_Pharmacological
omega 3/6 fatty acids
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Intervention_Pharmacological
omega 3/6
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Intervention_Control
placebo-controlled
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Intervention_Pharmacological
3 months with omega 3/6 for all
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Intervention_Pharmacological
omega 3/6 fatty acids
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Outcome_Mental
attention deficit hyperactivity disorder :
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Outcome_Mental
attention deficit hyperactivity disorder ( ADHD ) .
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Outcome_Mental
Investigator-rated ADHD Rating Scale-IV and Clinical Global Impression ( CGI ) scale
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Outcome_Mental
reduction of ADHD symptoms
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Outcome_Mental
drop of CGI scores
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Outcome_Mental
ADHD
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Outcome_Mental
ADHD
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Outcome_Mental
reduction of ADHD symptoms .
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Participant_Condition
children and adolescents .
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Participant_Condition
Responders tended to have ADHD inattentive subtype and comorbid neurodevelopmental disorders .
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Participant_Condition
A subgroup of children and adolescents with ADHD