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document
[ Comparative study between 5 % prilocaine and 2 % mepivacaine by the subarachnoid route in transurethral resections ] . OBJECTIVE To compare the duration of spinal block with 5 % prilocaine and 2 % mepivacaine in short procedures for transurethral resection and to assess possible complications in the immediate postoperative period . MATERIAL AND METHODS Fifty-seven patients scheduled for transurethral resection of the prostate or a vesical tumor . Patients were ASA I-III , over 55 years of age and randomly assigned to two groups to receive 5 % prilocaine ( 1 mg/kg , n = 27 ) or 2 % mepivacaine ( 0.8 mg/kg , n = 30 ) . We collected data on anesthetic technique , levels of extension of motor and sensory blockades , duration of blockades and complications within the first 24 hours after surgery . RESULTS Demographic data , ASA classification and duration of surgery were similar in both groups . We found statistically significant differences ( p < 0.05 ) in duration of sensory blockade ( 120.92 +/- 36.21 min with prilocaine and 145.83 +/- 35.81 min with mepivacaine ) and in motor blockade ( 106.29 +/- 38.16 min with prilocaine and 133.16 +/- 42.21 min with mepivacaine ) . Five cases of hypotension and 4 of bradycardia occurred in each group and one patient in the mepivacaine group suffered slight postoperative cephalea . CONCLUSIONS Both local anesthetics offer good surgical conditions with hemodynamic stability and few complications . The duration of sensory and motor blockade is shorter with prilocaine than with mepivacaine , making prilocaine more appropriate for short interventions .
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Intervention_Pharmacological
5 % prilocaine
3919
Intervention_Pharmacological
2 % mepivacaine
3920
Intervention_Pharmacological
5 % prilocaine
3921
Intervention_Pharmacological
2 % mepivacaine
3922
Intervention_Pharmacological
two groups to receive 5 % prilocaine ( 1 mg/kg , n = 27 )
3923
Intervention_Pharmacological
2 % mepivacaine ( 0.8 mg/kg , n = 30 )
3924
Intervention_Surgical
We collected data on anesthetic technique , levels of extension of motor and sensory blockades , duration of blockades and complications within the first 24 hours after surgery
3925
Intervention_Pharmacological
prilocaine
3926
Intervention_Pharmacological
mepivacaine
3927
Outcome_Other
duration
3928
Outcome_Adverse-effects
assess possible complications
3929
Outcome_Other
anesthetic technique
3930
Outcome_Other
levels of extension of motor and sensory blockades
3931
Outcome_Other
duration of blockades
3932
Outcome_Physical
complications within the first 24 hours
3933
Outcome_Other
duration of sensory blockade
3934
Outcome_Other
motor blockade
3935
Outcome_Adverse-effects
hypotension
3936
Outcome_Adverse-effects
bradycardia
3937
Outcome_Other
surgical conditions
3938
Outcome_Adverse-effects
complications
3939
Outcome_Other
sensory
3940
Outcome_Other
motor blockade
3941
Participant_Sample-size
Fifty-seven
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Participant_Condition
vesical tumor
3943
Participant_Age
55