78981
document
Fentanyl supplementation to inhalation anaesthesia . In eight out of 15 healthy patients undergoing body surface surgery , the effect of a fentanyl infusion on a conventional thiopentone , nitrous oxide , oxygen and halothane anaesthetic was studied . The fentanyl infusion ( 2 micrograms/kg/hour ) reduced the induction dose of thiopentone and caused marked respiratory depression with a reduction in the patients ' response to surgery . The mean arterial pressures and pulse rates were not significantly different in each group throughout the course of the operation . The fentanyl made no difference to the patients ' postoperative analgesic requirements or to their recovery in the first 24 hours .
78982
Intervention_Pharmacological
Fentanyl
78983
Intervention_Pharmacological
fentanyl infusion
78984
Intervention_Pharmacological
thiopentone , nitrous oxide , oxygen
78985
Intervention_Pharmacological
halothane anaesthetic
78986
Intervention_Pharmacological
fentanyl infusion
78987
Intervention_Pharmacological
fentanyl
78988
Outcome_Physical
induction dose of thiopentone
78989
Outcome_Physical
marked respiratory depression
78990
Outcome_Physical
mean arterial pressures
78991
Outcome_Physical
pulse rates
78992
Participant_Condition
inhalation anaesthesia
78993
Participant_Sample-size
eight
78994
Participant_Sample-size
15
78995
Participant_Condition
healthy
78996
Participant_Condition
body surface surgery