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document
Prophylactic amnioinfusion in pregnancies complicated by oligohydramnios : a prospective study . Prophylactic amnioinfusion was assessed in term and post-dates pregnancies with decreased amniotic fluid volume . Subjects were randomly assigned to one of three groups : amnioinfusion with warmed saline solution , room-temperature saline , or control . Patients receiving prophylactic amnioinfusion had a significant decrease in both the frequency and severity of variable decelerations in the first stage of labor ( P = .006 ) and in the average total number of variable decelerations in the first and second stages of labor ( P = .01 ) compared with controls . There was no observed effect on newborn serum electrolyte levels with amnioinfusion , nor was there any apparent benefit of infusion of warmed saline compared with room-temperature saline . In contrast to premature gestations with oligohydramnios , prophylactic amnioinfusion was not associated with a significant improvement in mean umbilical arterial and venous pH or a significant decrease in cesarean delivery for fetal distress ( P = .09 ) . This is perhaps because the term fetus has an enhanced ability to tolerate recurrent episodes of heart rate decelerations without demonstrating the rapid metabolic changes seen in the premature fetus .
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Intervention_Pharmacological
amnioinfusion
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Intervention_Pharmacological
amnioinfusion
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Intervention_Pharmacological
amnioinfusion
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Intervention_Pharmacological
warmed saline solution
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Intervention_Pharmacological
room-temperature saline
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Intervention_Control
control
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Intervention_Pharmacological
amnioinfusion
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Intervention_Pharmacological
amnioinfusion
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Intervention_Pharmacological
amnioinfusion
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Outcome_Physical
frequency and severity of variable decelerations in the first stage of labor
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Outcome_Physical
newborn serum electrolyte levels
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Outcome_Physical
mean umbilical arterial and venous pH
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Outcome_Other
significant decrease
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Outcome_Physical
cesarean delivery for fetal distress
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Outcome_Physical
heart rate decelerations
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Participant_Condition
Prophylactic amnioinfusion in pregnancies complicated by oligohydramnios :
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Participant_Condition
term and post-dates pregnancies with decreased amniotic fluid volume .