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Efficacy of a family practice-based lifestyle intervention program to increase physical activity and reduce clinical and physiological markers of vascular health in patients with high normal blood pressure and/or high normal blood glucose ( SNAC ) : study protocol for a randomized controlled trial . BACKGROUND Previous interventions to increase physical activity and reduce cardiovascular risk factors have been targeted at individuals with established disease ; less attention has been given to intervention among individuals with high risk for disease nor has there been determination of the influence of setting in which the intervention is provided . In particular , family practice represents an ideal setting for the provision and long-term maintenance of lifestyle interventions for patients at risk ( ie high-normal blood pressure or impaired glucose tolerance ) . METHODS/DESIGN The Staged Nutrition and Activity Counseling ( SNAC ) study is a randomized clustered design clinical trial that will investigate the effectiveness and efficacy of a multi-component lifestyle intervention on cardiovascular disease risk factors and vascular function in patients at risk in primary care . Patients will be randomized by practice to either a standard of care lifestyle intervention or a behaviourally-based , matched prescriptive physical activity and diet change program . The primary goal is to increase physical activity and improve dietary intake according to Canada 's Guides to Physical Activity Healthy Eating over 24 months . The primary intention to treat analysis will compare behavioral , physiological and metabolic outcomes at 6 , 12 and 24 months post-randomization including estimation of incident hypertension and/or diabetes . DISCUSSION The design features of our trial , and the practical problems ( and solutions ) associated with implementing these design features , particularly those that result in potential delay between recruitment , baseline data collection , randomization , intervention , and assessment will be discussed . Results of the SNAC trial will provide scientific rationale for the implementation of this lifestyle intervention in primary care . TRIAL REGISTRATION ISRCTN : ISRCTN:42921300 .
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Intervention_Educational
family practice-based lifestyle intervention program
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Intervention_Physical
multi-component lifestyle intervention
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Intervention_Educational
standard of care lifestyle intervention
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Intervention_Educational
behaviourally-based , matched prescriptive physical activity and diet change program
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Outcome_Other
physical activity
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Outcome_Physical
physical activity
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Outcome_Mental
dietary intake
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Outcome_Mental
Canada 's Guides to Physical Activity Healthy Eating
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Outcome_Physical
hypertension
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Outcome_Mortality
diabetes
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Participant_Condition
high normal blood pressure
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Participant_Condition
high normal blood glucose ( SNAC )
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Participant_Condition
high risk for disease
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Participant_Condition
high-normal blood pressure or impaired glucose tolerance