80439
document
Intraoperative microscopy of bile -- is it useful ? Direct microscopy of the bile was performed during cholecystectomy in 111 patients in an attempt to identify those with a high risk of wound infection . Bacteria were identified in 23 patients , 11 of 83 undergoing cholecystectomy alone and 12 of 28 undergoing exploration of the common bile duct ( P less than 0.01 ) . These 23 patients were randomly allocated to an antibiotic group or a control group ; there was one wound infection in the antibiotic group and two in the control group . A total of 14 patients developed wound sepsis . Infection was more likely if the common bile duct was explored ( 6 of 28 ) rather than cholecystectomy alone ( 8 of 83 ) . There was a poor correlation between microscopy and culture of the bile for bacteria and there was no increase in sepsis when bacteria were observed on microscopy . We were not able to identify a high risk group of patients by intraoperative microscopy of bile .
80440
Intervention_Other
Intraoperative microscopy
80441
Intervention_Physical
Direct microscopy of the bile
80442
Intervention_Surgical
cholecystectomy
80443
Intervention_Surgical
cholecystectomy
80444
Intervention_Pharmacological
antibiotic group
80445
Intervention_Pharmacological
antibiotic group
80446
Intervention_Control
control group
80447
Intervention_Surgical
cholecystectomy
80448
Outcome_Physical
wound sepsis .
80449
Outcome_Adverse-effects
Infection
80450
Outcome_Adverse-effects
bacteria
80451
Outcome_Physical
sepsis
80452
Participant_Condition
cholecystectomy
80453
Participant_Sample-size
111
80454
Participant_Sample-size
23
80455
Participant_Sample-size
11
80456
Participant_Sample-size
83
80457
Participant_Condition
cholecystectomy
80458
Participant_Sample-size
12
80459
Participant_Sample-size
28
80460
Participant_Condition
exploration of the common bile duct
80461
Participant_Sample-size
23
80462
Participant_Sample-size
14