93510
document
Study of cytosine arabinoside ( NSC-63878 ) synchronization plus vincristine ( NSC-67574 ) , prednisone ( NSC-10023 ) , and L-asparaginase ( NSC-109229 ) for remission induction in advanced acute leukemia in children . Cytosine arabinoside ( CA ) was utilized in efforts to synchronize leukemic cells in DNA synthesis for treatment with vincristine , prednisone , and L-asparaginase in children with acute leukemia in relapse . The results did not indicate any therapeutic advantage for patients treated with this combination compared to those treated without any attempt at CA synchronization .
93511
Intervention_Pharmacological
cytosine arabinoside
93512
Intervention_Pharmacological
synchronization plus vincristine
93513
Intervention_Pharmacological
prednisone
93514
Intervention_Pharmacological
L-asparaginase
93515
Intervention_Pharmacological
Cytosine arabinoside ( CA )
93516
Intervention_Pharmacological
vincristine
93517
Intervention_Pharmacological
prednisone
93518
Intervention_Pharmacological
L-asparaginase
93519
Intervention_Pharmacological
CA synchronization .
93520
Outcome_Physical
therapeutic advantage
93521
Participant_Condition
advanced acute leukemia
93522
Participant_Age
children
93523
Participant_Age
children
93524
Participant_Condition
acute leukemia in relapse