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document
Effect of fermented milk containing Lactobacillus casei strain Shirota on constipation-related symptoms and haemorrhoids in women during puerperium . Constipation and haemorrhoids are common complaints after childbirth . The objective of this pilot study was to evaluate impact of fermented milk containing Lactobacillus casei strain Shirota ( LcS ) on stool consistency and frequency , constipation-related symptoms and quality of life , and incidence of haemorrhoids in women during puerperium . Forty women who had natural childbirth were randomised to group consuming either one bottle/day of fermented milk containing at least 6.5×109 cfu of LcS , or placebo , for 6 weeks after childbirth . Subjects filled in a diary on their bowel habits including number of bowel movement , stool consistency and incidence of haemorrhoids , and answered questionnaires on constipation-related symptoms ( PAC-SYM ) and quality of life ( PAC-QOL ) during the study period . The probiotic group showed the better scores on overall PAC-SYM ( P=0.013 ) , PAC-SYM subscales of abdominal symptoms ( P=0.043 ) and rectal symptoms ( P=0.031 ) , and PAC-QOL satisfaction subscale ( P=0.037 ) in comparison with the placebo group . In the probiotic group , two to four subjects experienced haemorrhoids during the first 3 weeks of treatment . The number decreased in week 4 and no one had haemorrhoids on most days in week 5-6 . In the placebo group , on average four subjects had haemorrhoids from the beginning , and no obvious change was observed until week 6 . No statistically significant effect was observed on stool consistency and frequency . The study products did not cause any adverse event in the subjects . Results of this study indicate that continuous consumption of fermented milk containing LcS might alleviate constipation-related symptoms , provide satisfactory bowel habit and result in earlier recovery from haemorrhoids in women during puerperium . Nonetheless , there are several limitations in interpretation of the results attributed to the study design , including lack of baseline data . Further study is required in order to confirm the efficacy .
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Intervention_Pharmacological
fermented milk containing Lactobacillus casei strain Shirota
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Intervention_Pharmacological
fermented milk containing Lactobacillus casei strain Shirota ( LcS )
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Outcome_Physical
constipation-related symptoms and haemorrhoids
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Outcome_Physical
Constipation and haemorrhoids
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Outcome_Physical
stool consistency and frequency
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Outcome_Physical
constipation-related symptoms
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Outcome_Other
quality of life
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Outcome_Physical
incidence of haemorrhoids
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Participant_Condition
women during puerperium .
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Participant_Condition
Lactobacillus casei strain Shirota ( LcS )
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Participant_Condition
constipation-related symptoms
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Participant_Condition
natural childbirth
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Participant_Condition
placebo
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Participant_Condition
during puerperium