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document
A randomized trial evaluating the effects of change in dairy food consumption on cardio-metabolic risk factors . BACKGROUND It is currently not known whether dairy food influences the risk of cardiovascular disease or diabetes . This study evaluates effects of changing dairy intake on cardio-metabolic risk factors . METHODS 180 healthy volunteers were randomised to increase , reduce or not change their dairy intake for 1 month in response to dietary advice . Body weight , waist circumference , blood pressure , fasting plasma lipids , insulin resistance and C-reactive protein ( CRP ) were measured at baseline and after 1 month and compared by dietary group . RESULTS 176 ( 98 % ) subjects completed the study . Average change in self-reported dairy fat intake for increased dairy food was +0.9 SD 1.1 g/day ( +71 % ) , no change was -2.1 SD 0.4 g/day ( -15 % ) and decreased dairy food was -10.8 SD 1.2 g/day ( -77 % ) respectively . There was no statistically significant change in LDL or HDL cholesterol , triglycerides , systolic or diastolic blood pressure , C-reactive protein , glucose or insulin with 95 % CI standard mean differences < 0.2 for all and CRP < 0.3 . There was a small increase in weight ( +0.4 kg , SD 3.1 ) in those asked to increase dairy food . CONCLUSIONS In healthy volunteers , dietary advice to change dairy intake for 1 month did not have a clinically significant effect on cardio-metabolic risk factors . These observations suggest that dairy food can be included as part of a normal healthy diet without increasing cardio-metabolic risk . TRIAL REGISTRATION NUMBER ACTRN12612000574842 .
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Intervention_Physical
dairy food consumption
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Intervention_Physical
changing dairy intake
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Intervention_Physical
increase , reduce or not change their dairy intake for 1 month
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Outcome_Physical
cardio-metabolic risk factors
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Outcome_Physical
cardiovascular disease or diabetes
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Outcome_Physical
cardio-metabolic risk factors
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Outcome_Physical
Body weight , waist circumference , blood pressure , fasting plasma lipids , insulin resistance and C-reactive protein ( CRP )
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Outcome_Physical
self-reported dairy fat intake
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Outcome_Other
and decreased dairy food
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Outcome_Physical
change
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Outcome_Physical
LDL or HDL cholesterol
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Outcome_Physical
triglycerides
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Outcome_Physical
systolic or diastolic blood pressure
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Outcome_Physical
C-reactive protein
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Outcome_Physical
glucose or insulin
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Outcome_Physical
was a small increase in weight
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Outcome_Adverse-effects
effect on cardio-metabolic risk
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Outcome_Physical
increasing cardio-metabolic
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Participant_Sample-size
180 healthy volunteers
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Participant_Sample-size
176
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Participant_Condition
healthy