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[ Combined preoperative xeloda and radiotherapy for lower rectal cancer ] . OBJECTIVE To evaluate the effect of combined preoperative xeloda and pelvic radiotherapy on locally advanced lower rectal cancer . METHODS Sixty lower rectal cancer patients were divided randomly into two groups . 30 patients ( Group A ) were treated with operation alone and 30 patients ( Group B ) were treated with xeloda and radiotherapy before operation . RESULTS The operative resection , anal preservation and local recurrence rates were 86.66 % , 33.33 % , 15.38 % in group A and 100 % , 83.33 % , 0 % in group B ( P < 0.05 and P < 0.01 ) . CONCLUSION Combined preoperative xeloda and radiotherapy for lower rectal cancer is able to significantly improve the operative resection , anal preservation and decrease the local recurrence rates .
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Intervention_Pharmacological
preoperative xeloda
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Intervention_Pharmacological
radiotherapy
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Intervention_Pharmacological
combined preoperative xeloda and pelvic radiotherapy
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Intervention_Surgical
operation alone
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Intervention_Pharmacological
xeloda and radiotherapy before operation
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Intervention_Pharmacological
Combined preoperative xeloda and radiotherapy
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Outcome_Other
operative resection ,
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Outcome_Physical
anal preservation
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Outcome_Other
and local recurrence rates
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Participant_Condition
lower rectal cancer
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Participant_Condition
locally advanced lower rectal cancer
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Participant_Sample-size
Sixty
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Participant_Sample-size
30