79623
document
A randomized trial of intranasal beclomethasone dipropionate after polypectomy . Beneficial effects of intranasal beclomethasone dipropionate ( Bdp ) in patients with nasal polyposis have been reported earlier . This study was carried out to investigate whether long-term treatment with Bdp after polypectomy could prevent formation of new polyps and reduce the number of surgical removals . Forty consecutive patients without laboratory or other clinical signs of allergy but with severe nasal polyposis were included in the study . Twenty patients were treated with intranasal Bdp and twenty patients received no treatment after polypectomy . All patients were followed for at least 2.5 years . The size of the polyps that recurred was estimated at different time-intervals by the examining doctor . After six months there was already a significant difference in favour of the group treated with intranasal Bdp . Further results of the study and the clinical implications are discussed .
79624
Intervention_Pharmacological
beclomethasone dipropionate
79625
Intervention_Pharmacological
intranasal beclomethasone dipropionate ( Bdp )
79626
Intervention_Pharmacological
Bdp
79627
Intervention_Pharmacological
intranasal Bdp
79628
Intervention_Surgical
polypectomy
79629
Intervention_Pharmacological
Bdp
79630
Outcome_Physical
size of the polyps that recurred
79631
Outcome_Other
difference
79632
Participant_Condition
nasal polyposis
79633
Participant_Sample-size
Forty
79634
Participant_Condition
severe nasal polyposis
79635
Participant_Sample-size
Twenty
79636
Participant_Condition
intranasal Bdp
79637
Participant_Sample-size
twenty
79638
Participant_Condition
polypectomy