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document
Roles of adapalene in the treatment of pityriasis versicolor . BACKGROUND Ketoconazole is a typical treatment available for pityriasis versicolor ; tretinoin cream is effective , too . Adapalene gel is a tretinoin derivative and has a lower incidence of irritation compared with other topical retinoid products . However , there are no reports on adapalene gel for the treatment of pityriasis versicolor . OBJECTIVE To study the effect of adapalene gel comparing the treatment with adapalene gel and 2 % ketoconazole cream in pityriasis versicolor . METHODS Eighty patients suffering from pityriasis versicolor were randomly divided into two groups ; one group were treated with 2 % ketoconazole cream topically twice daily for 2 weeks , adapalene gel was used for the other group in a similar fashion . RESULTS There were no significant differences in efficacy between the two groups . No major side effects were noted in any of the groups either . CONCLUSION Adapalene was the favorable option in the treatment of pityriasis versicolor . The probable therapeutic mechanism of adapalene is also discussed .
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Intervention_Pharmacological
adapalene
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Intervention_Pharmacological
Ketoconazole
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Intervention_Pharmacological
tretinoin cream
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Intervention_Pharmacological
Adapalene gel
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Intervention_Pharmacological
adapalene gel
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Intervention_Pharmacological
adapalene gel
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Intervention_Pharmacological
adapalene gel
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Intervention_Pharmacological
2 % ketoconazole cream
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Intervention_Pharmacological
2 % ketoconazole cream
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Intervention_Pharmacological
adapalene gel
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Intervention_Pharmacological
Adapalene
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Intervention_Pharmacological
adapalene
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Outcome_Other
Roles of adapalene
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Outcome_Adverse-effects
irritation
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Outcome_Other
efficacy
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Outcome_Adverse-effects
side effects
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Participant_Condition
pityriasis versicolor
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Participant_Condition
pityriasis versicolor
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Participant_Condition
pityriasis versicolor
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Participant_Condition
pityriasis versicolor
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Participant_Sample-size
Eighty
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Participant_Condition
pityriasis versicolor
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Participant_Condition
pityriasis versicolor