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document
Adequacy of " hot biopsy " for the treatment of diminutive polyps : a prospective randomized trial . Patients with diminutive polyps in the rectum or sigmoid colon were randomized to " hot biopsy " treatment for either 1 ) electrocautery for 2 s ( fixed duration cautery ) or 2 ) cautery until visible necrosis of the polyp base was evident ( variable duration cautery ) . Sigmoidoscopy was performed 4 wk after treatment to determine the adequacy of polyp eradication . In the fixed duration cautery group , 11 of 21 polyps ( 52 % ) were eradicated , compared with 12 of 14 polyps ( 86 % ) in the variable duration cautery group ( p = 0.04 ) . When analyzed according to whether or not visible necrosis was achieved ( some of the polyps in the fixed duration cautery group showed necrosis with 2 s cautery ) , 19 of 23 polyps ( 83 % ) were eradicated when necrosis was evident , compared to 5 of 12 ( 42 % ) without necrosis ( p = 0.004 ) . We conclude that hot biopsy treatment for diminutive polyps is significantly more effective when visible necrosis is achieved during cautery . Furthermore , even with visible necrosis , there is a 17 % failure rate of polyp eradication .
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Intervention_Surgical
electrocautery
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Intervention_Surgical
cautery until visible necrosis of the polyp base was evident
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Intervention_Physical
Sigmoidoscopy
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Outcome_Physical
eradicated
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Outcome_Physical
visible necrosis
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Outcome_Physical
eradicated
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Participant_Condition
Patients with diminutive polyps in the rectum or sigmoid colon