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document
National Surgical Adjuvant Breast and Bowel Project 's Breast Cancer Prevention Trial . The Breast Cancer Prevention Trial is the largest breast cancer prevention study ever undertaken . Administered by the National Surgical Adjuvant Breast and Bowel Project , it is the first trial seeking to demonstrate whether a drug , tamoxifen , can prevent breast cancer in high-risk women . The objectives of this trial are to determine whether tamoxifen is effective in 1 ) reducing the incidence of invasive breast cancer , 2 ) reducing breast cancer mortality , 3 ) reducing deaths from cardiovascular disease , and 4 ) reducing bone fractures . In addition , the study will evaluate side effects , toxicity , and the quality of life of all study participants .
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Intervention_Pharmacological
tamoxifen
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Intervention_Pharmacological
tamoxifen
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Outcome_Physical
reducing the incidence of invasive breast cancer
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Outcome_Mortality
reducing breast cancer mortality
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Outcome_Mortality
reducing deaths from cardiovascular disease
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Outcome_Physical
reducing bone fractures
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Outcome_Adverse-effects
side effects ,
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Outcome_Mortality
toxicity
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Outcome_Other
quality of life
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Participant_Condition
tamoxifen