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document
[ Effect of Selaginella combined with radiotherapy on nasopharyngeal carcinoma ] . OBJECTIVE To observe the Chinese herbal medicine Selaginella-induced radiosensitization of terminal nasopharyngeal carcinoma ( NPC ) . METHODS Totally 180 patients with NPC were divided equally into 3 groups with the same radiotherapeutic protocols . The patients in group A received radiotherapy alone , those in group B were given daily Selaginella ( 30 g ) prepared into 50 ml decoction during the entire course of radiotherapy , and those in group C had Selaginella 30 g daily in the late course of radiotherapy . RESULTS The complete remission rate of nasopharyngeal primary lesions in groups B and C was significantly higher than that in group A , with also significantly higher complete remission rates of the cervical lymph nodes . The acute toxicity of the skin and mucous membrane was milder in the latter two groups , but the differences were not significant . CONCLUSION Selaginella may induce radiosensitization for terminal NPC and does not increase the acute toxicity of radiotherapy .
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Intervention_Pharmacological
Selaginella
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Intervention_Physical
radiotherapy
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Intervention_Physical
radiotherapy alone
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Intervention_Pharmacological
daily Selaginella ( 30 g ) prepared into 50 ml decoction during the entire course of radiotherapy
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Intervention_Pharmacological
group C had Selaginella 30 g daily
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Intervention_Pharmacological
radiotherapy
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Intervention_Pharmacological
Selaginella
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Outcome_Physical
complete remission rate of nasopharyngeal primary lesions
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Outcome_Physical
remission rates of the cervical lymph nodes
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Outcome_Physical
acute toxicity of the skin and mucous membrane
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Participant_Condition
nasopharyngeal carcinoma
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Participant_Condition
terminal nasopharyngeal carcinoma ( NPC )
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Participant_Sample-size
180
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Participant_Condition
NPC
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Participant_Condition
terminal NPC