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document
Efficacy of azithromycin for the treatment of feline chlamydophilosis . The current recommended treatment for feline chlamydophilosis involves daily oral administration of antimicrobials to all cats within an affected group for a prolonged period of time ( 4-6 weeks ) . Not surprisingly , owner compliance can be poor resulting in apparent treatment failure . Recent anecdotal evidence , supported by its efficacy in the treatment of Chlamydia trachomatis infection in humans , has suggested that azithromycin may offer an alternative by allowing less frequent dosing for a shorter duration . A clinical trial was designed to evaluate the efficacy of azithromycin for the treatment of chlamydia ( Chlamydophila felis ) infection in cats . Whilst azithromycin , given at 10-15 mg/kg daily for 3 days and then twice weekly , provided a similar , rapid resolution of clinical signs and negative isolation scores as doxycycline , C felis was re-isolated in four out of the five cats treated . Furthermore , even daily administration of azithromycin to chronically infected cats was ineffective in clearing infection . The azithromycin protocols used here were therefore found to be unsuccessful in eliminating the carriage of this strain of C felis .
15293
Intervention_Pharmacological
azithromycin
15294
Intervention_Pharmacological
antimicrobials
15295
Intervention_Pharmacological
azithromycin
15296
Intervention_Pharmacological
azithromycin
15297
Intervention_Pharmacological
azithromycin
15298
Intervention_Pharmacological
doxycycline
15299
Intervention_Pharmacological
azithromycin
15300
Outcome_Other
Efficacy
15301
Outcome_Other
efficacy
15302
Outcome_Other
efficacy
15303
Outcome_Other
similar , rapid resolution of clinical signs and negative isolation scores
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Outcome_Physical
ineffective in clearing infection .
15305
Outcome_Physical
unsuccessful in eliminating the carriage of this strain of C felis .