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document
Comparison of 5-aminosalicylic acid ( 3 g ) and prednisolone phosphate sodium enemas ( 30 mg ) in the treatment of distal ulcerative colitis . A prospective , randomized , double-blind trial . Twenty-nine patients with attacks of distal ulcerative colitis were treated randomly with 3 g 5-aminosalicylic acid ( 5-ASA ) or 30 mg of prednisolone phosphate sodium ( PP ) enemas ( 40 ml ) . Endoscopic , clinical , and histologic improvement were comparable in the two treatment groups . Our study showed that topical treatment with 5-ASA is as efficacious as PP in improving distal ulcerative colitis .
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Intervention_Pharmacological
5-aminosalicylic acid
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Intervention_Pharmacological
prednisolone phosphate sodium
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Intervention_Pharmacological
5-aminosalicylic acid ( 5-ASA )
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Intervention_Pharmacological
prednisolone phosphate sodium ( PP )
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Intervention_Pharmacological
5-ASA
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Intervention_Pharmacological
PP
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Outcome_Physical
distal ulcerative colitis
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Outcome_Physical
Endoscopic , clinical , and histologic improvement
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Outcome_Physical
distal ulcerative colitis
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Participant_Condition
distal ulcerative colitis
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Participant_Sample-size
Twenty-nine patients
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Participant_Condition
attacks of distal ulcerative colitis
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Participant_Condition
distal ulcerative colitis