80891
document
A comparison of live and videotape ratings : clomipramine and haloperidol in autism . This study compared live ratings with ratings of videotapes and compared response to clomipramine with response to haloperidol in 8 subjects , mean age 5.62 years , who met criteria for autism . They were consecutive admissions to a pilot study of clomipramine ( n = 4 ) or a double-blind , placebo controlled study of haloperidol ( n = 4 ) . Live ratings were performed by two raters at the end of the pre-treatment placebo baseline period and at the end of the drug treatment period on the CPRS and the CGI and were videotaped . Employing the same instruments , these videotapes were rated by two raters who did not know the subjects and were blind to study design , treatment , and study phase . Ratings of videotapes significantly differed from live ratings . A treatment effect for haloperidol was detected only on live ratings and not on ratings of videotapes . No treatment effect was detected for clomipramine in either live or videotape ratings .
80892
Intervention_Pharmacological
clomipramine
80893
Intervention_Pharmacological
haloperidol
80894
Intervention_Pharmacological
clomipramine
80895
Intervention_Pharmacological
haloperidol
80896
Intervention_Pharmacological
clomipramine
80897
Intervention_Control
placebo
80898
Intervention_Pharmacological
haloperidol
80899
Intervention_Control
placebo
80900
Intervention_Pharmacological
clomipramine
80901
Outcome_Other
Ratings of videotapes
80902
Outcome_Other
live ratings
80903
Outcome_Other
live ratings
80904
Outcome_Other
ratings of videotapes
80905
Outcome_Other
live
80906
Outcome_Other
videotape ratings
80907
Participant_Condition
clomipramine
80908
Participant_Condition
haloperidol in autism
80909
Participant_Sample-size
8
80910
Participant_Age
5.62 years