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document
Gender differences in response to nicotine replacement therapy : objective and subjective indexes of tobacco withdrawal . K. A. Perkins ( 1996 ) recently proposed that nicotine reinforcement controls smoking to a greater degree among men than women and that consequently , nicotine replacement therapy ( NRT ) during smoking cessation should benefit men more than women . The authors tested this hypothesis . Polysomnographic measures of sleep and self-report indexes of tobacco withdrawal were collected pre- and postcessation from an active nicotine patch group and a placebo patch group in a randomized , double-blind clinical trial ( N = 34 ) . Objective sleep parameters supported Perkins 's hypothesis and indicated that among women , NRT may be less effective at suppressing certain withdrawal responses compared with men and may produce some iatrogenic effects . Valid and reliable self-report measures of withdrawal did not reveal gender differences in response to NRT .
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Intervention_Pharmacological
nicotine replacement therapy
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Intervention_Other
nicotine reinforcement
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Intervention_Pharmacological
nicotine replacement therapy ( NRT )
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Intervention_Pharmacological
nicotine patch
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Intervention_Control
placebo patch
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Intervention_Physical
NRT
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Intervention_Pharmacological
NRT
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Outcome_Physical
sleep and self-report indexes
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Outcome_Physical
suppressing certain withdrawal responses
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Outcome_Physical
may produce some iatrogenic effects
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Outcome_Other
withdrawal did not reveal gender differences in response to NRT .