41308
document
Efficacy of prepackaged , low residual test meals with 4L polyethylene glycol versus a clear liquid diet with 4L polyethylene glycol bowel preparation : a randomized trial . BACKGROUND AND STUDY AIMS A prepackaged low residue one-day diet ( breakfast , lunch and dinner ) has been recently developed to improve patient tolerance for bowel preparation prior to colonoscopy . The aims of this study were to evaluate the efficacy and tolerability of bowel preparation protocols based on a low residue diet and 4L polyethylene glycol ( PEG ) solution , and to compare these new options with the traditional liquid diet and the PEG 4L lavage . METHODS A total of 214 patients ( mean age : 54.1 years ; 120 male , 94 female ) from four university hospitals were included in the analysis . Patients were randomized to receive a clear liquid diet and the PEG 4L regimen ( 106 patients ) or the low residue test meals and the PEG 4L regimen ( TM-PEG 4L , 108 patients ) . The colon cleansing efficacy of the different preparations was rated using the Ottawa bowel preparation scale . RESULTS No significant differences were observed between the treatment groups according to the Ottawa cleansing scale findings ( PEG 4L : 2.97 vs TM-PEG 4L : 2.46 , P = 0.063 ) . The overall tolerability was higher in the TM-PEG 4L group than in the PEG 4L group ( P = 0.036 ) . No difference was found when the two groups were compared with regard to adverse events ( P = 0.599 ) . CONCLUSIONS A prepackaged low residue one-day diet provided cleansing efficacy similar to that of a clear liquid diet and offered the benefit of improved tolerability compared to the conventional PEG 4L regimen .
41309
Intervention_Pharmacological
prepackaged , low residual test meals with 4L polyethylene glycol
41310
Intervention_Pharmacological
clear liquid diet with 4L polyethylene glycol bowel preparation
41311
Intervention_Pharmacological
low residue diet
41312
Intervention_Pharmacological
4L polyethylene glycol ( PEG ) solution
41313
Intervention_Pharmacological
traditional liquid diet and the PEG 4L lavage
41314
Intervention_Pharmacological
clear liquid diet and the PEG 4L regimen
41315
Intervention_Pharmacological
low residue test meals and the PEG 4L regimen ( TM-PEG
41316
Outcome_Other
Efficacy
41317
Outcome_Physical
patient tolerance for bowel preparation
41318
Outcome_Other
efficacy
41319
Outcome_Other
tolerability
41320
Outcome_Other
colon cleansing efficacy
41321
Outcome_Physical
Ottawa bowel preparation scale
41322
Outcome_Physical
Ottawa cleansing scale
41323
Outcome_Physical
overall tolerability
41324
Outcome_Adverse-effects
adverse events
41325
Outcome_Other
cleansing efficacy
41326
Outcome_Physical
improved tolerability