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document
Comparison between intermittent mandatory ventilation and synchronized intermittent mandatory ventilation with pressure support in children . OBJECTIVE To compare intermittent mandatory ventilation ( IMV ) with synchronized intermittent mandatory ventilation plus pressure support ( SIMV+PS ) in terms of time on mechanical ventilation , duration of weaning and length of stay in a pediatric intensive care unit ( PICU ) . METHODS This was a randomized clinical trial that enrolled children aged 28 days to 4 years who were admitted to a PICU between October of 2005 and June of 2007 and put on mechanical ventilation ( MV ) for more than 48 hours . These patients were allocated to one of two groups by drawing lots : IMV group ( IMVG ; n = 35 ) and SIMV+PS group ( SIMVG ; n = 35 ) . Children were excluded if they had undergone tracheotomy or had chronic respiratory diseases . Data on oxygenation and ventilation were recorded at admission and at the start of weaning . RESULTS There were no statistical differences between the groups in terms of age , sex , indication for MV , PRISM score , Comfort scale , use of sedatives or ventilation and oxygenation parameters . The median time on MV was 5 days for both groups ( p = 0.120 ) . There were also no statistical differences between the two groups for duration of weaning [ IMVG : 1 day ( 1-6 ) vs. SIMVG : 1 day ( 1-6 ) ; p = 0.262 ] or length of hospital stay [ IMVG : 8 days ( 2-22 ) vs. SIMVG : 6 days ( 3-20 ) ; p = 0.113 ] . CONCLUSION Among the children studied here , there was no statistically significant difference between IMV and SIMV+PS in terms of time on MV , duration of weaning or time spent in the PICU . ClinicalTrials.govID : NCT00549809 .
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Intervention_Physical
intermittent mandatory ventilation
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Intervention_Physical
synchronized intermittent mandatory ventilation
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Intervention_Physical
pressure support
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Intervention_Physical
intermittent mandatory ventilation ( IMV )
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Intervention_Physical
synchronized intermittent mandatory ventilation plus pressure support ( SIMV+PS )
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Intervention_Physical
mechanical ventilation ( MV )
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Intervention_Physical
IMV
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Intervention_Physical
( IMVG
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Intervention_Physical
SIMV+PS
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Intervention_Physical
SIMVG
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Intervention_Physical
IMVG
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Intervention_Physical
SIMVG
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Intervention_Physical
IMVG
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Intervention_Physical
SIMVG
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Intervention_Physical
IMV
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Intervention_Physical
SIMV+PS
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Outcome_Physical
time on mechanical ventilation
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Outcome_Other
, duration of weaning and length of stay in a pediatric intensive care unit
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Outcome_Physical
oxygenation
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Outcome_Other
and
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Outcome_Physical
ventilation
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Outcome_Other
age , sex , indication for MV , PRISM score , Comfort scale , use of sedatives or ventilation and oxygenation parameters .
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Outcome_Other
median time on MV
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Outcome_Other
duration of weaning
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Outcome_Other
length of hospital stay
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Outcome_Other
MV , duration of weaning or time spent in the PICU .
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Participant_Age
children
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Participant_Age
children aged 28 days to 4 years
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Participant_Condition
PICU
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Participant_Age
Children
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Participant_Condition
chronic respiratory diseases .
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Participant_Age
children