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No Evidence for a Relationship Between Infiltrates in Renal Protocol Biopsies and Outcome

With interest we read the meticulous report from Mengel and colleagues (1) describing type, location and composition of cellular infiltrates in renal allograft biopsies. Furthermore, they propose a relationship between infiltrates in renal protocol biopsies and outcome: persistent inflammation over the first 6 months posttransplant would predict inferior renal function. We disagree with this conclusion, as the manuscript does not contain sufficient evidence to support their hypothesis: