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The distribution of aldose and aldehyde reductases in different regions of human and bovine kidney.

Human and Bovine kidney aldose and aldehyde reductases from cortex, medulla and papilla have been purified by DE-52 column chromatography or chromatofocusing and have been biochemically characterized. In both human and bovine kidney, cortex contains only aldehyde reductase and papilla aldose reductase. Medulla however, contains aldose as well as aldehyde reductase.