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Association Of Serum Tumour Necrosis Factor‐α With Serum Low‐Density Lipoprotein–Cholesterol And Blood Pressure In Apparently Healthy Japanese Women

1. The pro‐inflammatory cytokine tumour necrosis factor (TNF)‐α is considered to be involved in the development of atherosclerosis by inducing local inflammatory responses in the vascular wall. Because TNF‐α is also known to affect lipid and glucose metabolism, the association between the circulating concentration of TNF‐α and atherogenic risk factors was examined in 82 apparently healthy Japanese women (aged 19–69 years; mean age 48.5 years).