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Serum and gene expression levels of CT‐1, IL‐6, and TNF‐α after a lifestyle intervention in obese children

Inflammation related molecules such as tumor necrosis factor‐α (TNF‐α), interleukin 6 (IL‐6), and cardiotrophin‐1 (CT‐1) are highly expressed in obese individuals and could partly explain some comorbidities associated to obesity. In obese children, lifestyle interventions are able to lower inflammation and reduce cardiovascular risk factors associated with obesity. The aim of the present work was to study changes in inflammation‐related molecules serum and peripheral blood mononuclear cells (PBMC) transcript levels after a 10‐week lifestyle intervention in obese children and asses their potential association with glucose metabolism.