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Proposed classification of various limit values (guide values) used in assisting the interpretation of quantitative laboratory test results

In a recent editorial, Henny pointed out (1) that our attempt to classify the various concepts for the determination of reference and/or decision limits may be confusing. Therefore, we propose a simplified version of the recent classification scheme (2). Various limits are used in assisting the interpretation of quantitative laboratory results. These limits always discriminate between at least two subgroups of the population served by a particular laboratory, mostly with a specified statistical significance (Table 1):