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A potential contribution of decreased serum galectin‐10 levels to systemic inflammation and pulmonary vascular involvement in systemic sclerosis

Galectin‐10 (Gal‐10) is a key molecule involved in eosinophil‐mediated suppression of T‐cell immune response. Systemic sclerosis (SSc) is characterized by T helper (Th) 2/Th17 immune response and impaired function of regulatory T cells, but the pathological role of Gal‐10 has not been studied so far. Therefore, we investigated the clinical correlation of serum Gal‐10 levels in SSc patients.