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The effect of an intrauterine contraceptive device on the mast cell content of the human myometrium: a preliminary report.

Mast cells in the human myometrium did not show significant changes either quantitatively or morphologically in the different phases of the menstrual cycle or when studied in different patterns of dysfunctional bleeding. Significant reduction in the mast cell population of the uterine muscle occurred after insertion of the IUD irrespective of the clinical condition. The possible cause of this universal reduction is discussed.(FULL TEXT)