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Clinical Features and Visual Outcome of Uveitis in Japanese Patients Younger than 18 Years

ABSTRACT Purpose: To investigate the clinical features and visual outcome of young Japanese patients with uveitis. Methods: Patients younger than 18 years who presented with uveitis at the University of Tokyo Hospital between 2000 and 2018 were retrospectively reviewed. Results: The study comprised 98 patients whose mean age was 12.3 ± 3.8 years. Anterior uveitis was present in 52.0%, panuveitis in 37.8%, and posterior uveitis in 10.2%. The most common diagnosis was juvenile chronic iridocyclitis (JCI) (29.6%) followed by tubulointerstitial nephritis and uveitis syndrome (4.1%) and neuroretinitis (4.1%). Thirty-nine patients received systemic anti-inflammatory treatment. Among all subjects, 56% presented with ocular complications and 20% underwent ocular surgery. Visual acuity of 20/200 or less was observed in 6.2%. The common causes of decreased vision were hypotony, serous retinal detachment, and pupil disorder. Conclusions: JCI was the most common diagnosis. Hypotony, serous retinal detachment, and pupil disorder can lead to visual loss.