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Autoimmune neurological disease after cardiac surgery

A recent report on three patients who developed myasthenia gravis (MG) three to 10 weeks after cardiac surgery1 raised the intriguing possibility that thoracotomy, by damaging the thymus, could precipitate MG. MG is an autoimmune disorder, associated with autoantibodies that bind to the acetylcholine receptor (AChR) or to muscle specific kinase (MuSK) at the neuromuscular junction. The thymus gland is clearly involved in the aetiology of some …