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Cell viability study of green synthesized CdTe/CdSe quantum dots against osteosarcoma cell line for improved therapeutic action

LM-8 is a murine osteosarcoma cell line associated with bone tumor in young adult and children. It contains the nuclear factor-κB which make this cell high resistance to irradiation thus limiting its treatment only to chemotherapy and surgery which has become a source of concerned for cancer therapy. In addressing this problem, we herein report the synthesis of CdTe/CdSe core/shell quantum dots (QDs) via a simple, reproducible method and its cytotoxic action against the LM-8 cell line. The cell viability study shows that the as-synthesized QDs are toxic to the LM-8 cell line in a concentration- and time-dependent manner.