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Pituitary Causes of Amenorrhea

Pituitary causes of amenorrhea should be considered in women with low or normal gonadotropin levels. Pituitary causes of amenorrhea constitute 18% of cases of secondary amenorrhea and 7% of cases of primary amenorrhea (1). Hyperprolactinemia is the most common cause of pituitary amenorrhea, comprising 15% of all cases of secondary amenorrhea and 80% of pituitary cases of secondary amenorrhea (2). This review will highlight potential causes of pituitary amenorrhea.