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Meaningful treatment outcomes in Alzheimer’s disease

Goal Attainment Scaling allows for problems identified by patients and carers to be the focus of treatment

The explosion of interest in clinical trials for the treatment of the symptoms of Alzheimer’s disease has resulted in an industry developing instruments, which assess the disorder and the changes that can occur as a result of interventions.1 The ability to quantify phenomena is an essential prerequisite to measure the effects of any treatments.

The questioning of the relevance of a purely cognitive approach to monitoring change in Alzheimer’s disease—that is, the understandable doubt as to the clinical relevance of, say, remembering eight as opposed …