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Urine Amino Acid Analysis in 113 Healthy Children

Objective To learn the aminogram of urine in normal infants and young children in a relatively large sample of control groups.Methods 20 kinds of amino acids in urine samples were analysed in 113 healthy children younger than 4-year-old by RP-HPLC with HP1050.Results A relatively broad credibility interval was detected in each amino acid and most showed normal distribution except some.Our study revealed a significant decreasing trend with age but without sex differences.Conclusions There's a significant decreasing trend with age but without sex differences in urine amino acids in healthy children younger than 4-year-old.The aminogram of urine in children can help in differential diagnosis in some diseases.