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Author Response: Effect of Levetiracetam Use Duration on Overall Survival of Isocitrate Dehydrogenase Wild-Type Glioblastoma in Adults: An Observational Study

We read with great interest the comment on our article.1 Epilepsy is associated with an improved survival in the context of glioblastomas and diffuse low-grade gliomas, as studied by our team.2 This differs from the research cited by Mazzucchi et al.3 in which persistent seizures after surgery were associated with a shorten survival. This is probably related to the fact that our study considered seizures and seizure control at diagnosis, not after surgery. The extent of resection is itself a clear predictor of both postoperative seizure control and survival, making the argument circular and difficult to analyze.