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Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children

MAIN RESULTS Patients in the ibuprofen group had greater improvement in pain scores at 60 minutes than those in the acetaminophen and codeine groups (table). At 60 minutes more children in the ibuprofen group than in the acetaminophen or codeine groups achieved adequate analgesia. Groups did not differ for the number of patients who needed additional analgesia (14% for ibuprofen, 16% for acetaminophen, and 22% for codeine).