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Metastatic lobular carcinoma of the breast diagnosed in cervicovaginal samples. A case report.

BACKGROUND
Malignant tumors with extragenital origins are rare in cervicovaginal samples.


CASE
A case of metastatic lobular carcinoma of the breast was diagnosed in a cervicovaginal smear. Histologic correlation was performed. Marker studies for carcinoembryonic antigen, human milk fat globule membrane, epidermal growth factor receptor, epithelial membrane antigen and cytokeratin were positive.


CONCLUSION
Recognition of extrauterine cancer in the cervicovaginal smear has important diagnostic, prognostic, and therapeutic implications.