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Increased association of the ERG oncoprotein expression in advanced stages of prostate cancer in Filipinos

Filipinos with prostate cancer (CaP) are at increased risk of harboring advanced stages and lower survival rates compared to other Asians. This study aims to investigate prevalence of ETS‐related gene (ERG) oncoprotein overexpression in Filipinos as surrogate of TMPRSS2‐ERG gene fusions, using a highly specific monoclonal antibody (ERG‐MAb), and conduct the first attempt to study the role of genetic alterations in the aggressive tumor biologic behaviour of CaP among Filipinos.