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Aqueduct Gliosis Caused by Keratin and Cholesterol In a Case of Craniopharyngioma

Summary Keratin and cholesterol particles released by a craniopharyngioma were shown to be the agents involved in the production of a foreign-body granulomatous arachnoiditis and ependymitis. Some of the particles were seen embedded in the reactive subepen-dymal glial tissue along the aqueduct of Sylvius. It was thought they were a major factor leading to the aqueduc-tal stenosis. However, we have also considered that the change in cerebro-spinal fluid hydrodynamics following the ventriculopleural shunt contributed to the occlusion of the aqueduct.