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Intrapartum stress Sowers the concentration of high density lipoprotein cholesterol in cord plasma

Abstract. The concentration of cord plasma triglycer‐ides, total cholesterol, high density lipoprotein (HDL) cholesterol, and apoprotein AI and All has been measured in acidotic and non‐acidotic full‐term neonates without chronic maternal‐fetal problems. The level of cord plasma triglycerides was significantly increased (P<005) and that of HDL cholesterol significantly decreased (P< 0–001) in the newborns belonging to the quintile class with the lowest blood PH (≤ No differences were present between the acidotic and non‐acidotic neonates in the plasma concentrations of total cholesterol or of apoprotein AI and All. The concentration of triglycerides was increased (<005) and that of HDL cholesterol was decreased (P<005) in the infants with the longest duration of labour. No correlation was observed between the concentrations of glycerol and lipids or lipoproproteins in cord plasma. The results suggest that intrapartum stress raises plasma triglycerides and induces qualitative and quantitative changes in the plasma high density lipoprotein fraction in the newborn.