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Recurrent herpes and post-traumatic stress disorder.

A 33-year-old male presented with recurrent outbreaks of perioral herpes of disfiguring nature that remained unresolved following therapy. The first perioral outbreak occurred following a road accident. The psychiatric interview conducted with the patient suggested post-traumatic stress disorder (PTSD) secondary to the accident. Venlafaxine 50 mg/day was initiated and led to resolution of the PTSD symptoms within 8 weeks. The patient did not experience any further herpes outbreaks for about 10 months. Control of stress disorders in recurrent herpes is discussed from a therapeutic perspective.