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Relationships between cognitive test performance and everyday cognitive difficulties in multiple sclerosis.

Cognitive test performance and rated everyday cognitive difficulties were compared in 29 subjects with multiple sclerosis. Modest relationships between test and questionnaire measures were found. The correlation between test and everyday measures was higher when informants' ratings of everyday problems were used rather than subjects' own ratings. The size of the discrepancy between subject and informant ratings was related to subjects' performance on tests considered sensitive to frontal lobe dysfunction.