SKU: P115  / 
    CAS Number: 172820-23-4

    Pexiganan acetate

    Pexiganan is an antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Bacterial resistance to pexiganan is very unlikely to develop.
    Mechanism of ActionPexiganan adopts a helix form in the cell membrane, causing pores in the membrane and leakage leading to cell death.
    Molecular FormulaC122H210N32O22
    ReferencesGottler, L. M., & Ramamoorthy, A. (2009). Structure, membrane orientation, mechanism, and function of pexiganan — A highly potent antimicrobial peptide designed from magainin. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1788(8), 1680–1686. doi:10.1016/j.bbamem.2008.10.009