TY - JOUR A1 - Styring, Peter A1 - Parracho, Ana I. R. T1 - From discovery to production: Scale-out of continuous flow meso reactors JF - Beilstein Journal of Organic Chemistry Y1 - 2009/// VL - 5 SP - 29 SN - 1860-5397 M3 - doi:10.3762/bjoc.5.29 N2 - A continuous flow parallel reactor system has been developed to provide a rapid and seamless transition from the discovery phase and production phase of chemical synthesis, particularly in low volume-high value pharmaceuticals production. Using a single fixed bed catalytic meso reactor, reactions can be screened on a small discovery scale over short time scales. The intensified process produces sufficient material for a full analysis. By replication of the single reactor in parallel, the same chemistry can be achieved on a larger scale, on a small footprint and without the mass and heat transport limitations of reactor scale-out in batch. ER -