1,269 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1

    Yi Ren et al.
    Biochemical and structural analyses of a universal mRNP remodeling pathway suggest an ATPase-powered targeted deposition of export factors onto mRNP.
    1. Cell Biology

    Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain

    Nadia Formicola et al.
    Tyramine-dependent signaling triggers decondensation of neuronal RNP components and rapid translation activation of target mRNAs.
    1. Computational and Systems Biology


    Athma A Pai et al.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Global donor and acceptor splicing site kinetics in human cells

    Leonhard Wachutka et al.
    1. Structural Biology and Molecular Biophysics

    Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex

    Sandra K Schuller et al.
    The THO-Sub2 complex is an asymmetric homodimer that uses the spatial arrangement of two Sub2 helicases to prevent RNA:DNA hybrids.
    1. Structural Biology and Molecular Biophysics

    Acidic C-terminal domains autoregulate the RNA chaperone Hfq

    Andrew Santiago-Frangos et al.
    Modeling and biophysics show that the unstructured acidic tail of the Sm protein Hfq mimics nucleic acid to auto inhibit its chaperone activity, preventing Hfq from being sequestered by inauthentic substrates and providing insight into the evolution of Hfq's chaperone function among bacterial genera.
    1. Computational and Systems Biology
    2. Developmental Biology


    Sumeda Nandadasa et al.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Single-cell analysis of transcription kinetics across the cell cycle

    Samuel O Skinner et al.
    1. Biochemistry and Chemical Biology

    Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

    Zhaofeng Gao et al.

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