text: c 
  10 
  
  . 
  e 
  . 
  s 
  8  n 
  i 
  
  n 
  o 
  i 
  t 
  c 
  u 
  d 
  e 
  r 
  d 
  o 
  F 
  
  6 
  
  4 
  l 
  
  Best rare variant cut-off 
  2 
  0  5,000  2,000 
  1,000 
  Cut-off time (generations) 
  4,000  3,000 
  
  Theoretical prediction 
  
  d 
  1,500 
  
  f 
  f 
  o 
  - 
  t 
  u 
  c 
  
  s 
  t 
  a 
  t 
  s 
  g 
  w 
  T 
  
  1,000 
  i 
  
  500 
  l 
  a 
  m 
  i 
  t 
  p 
  O 
  0 
  
  0 
  500 
  Source split time 
  1,000  1,500 