text: In humans, reductions in gray matter volume (GMV) have 
  been observed postpartum13–16, particularly in regions central to 
  theory-of-mind processing13. These GMV changes persist at 6 years 
  postpartum17 and are traceable decades later18,19, underscoring the 
  permanence of this major remodeling event. And yet the changes that 
  occur within the maternal brain during gestation itself are virtually 
  unknown (see ref. 20 for early neuroimaging insight). A recent study by 
  Paternina-Die et al. offers intriguing clues21. Women were scanned once 
  in the third trimester and again in the postpartum period, revealing a 
  reduction of cortical volume observable in the late pregnancy scan. 
  These findings suggest that pregnancy is a highly dynamic period for 
  neural remodeling, yet neuroscientists lack a detailed map of how the 
  human brain changes throughout the gestational period. 
  
  Here we conducted a precision imaging study of pregnancy in 
  which a healthy 38-year-old primiparous woman underwent 26 mag- 
  netic resonance imaging (MRI) scans and venipuncture beginning 
  3 weeks preconception through 2 years postpartum. We observed 
  widespread reductions in cortical GMV and cortical thickness (CT) 
  occurring in step with advancing gestational week and the dramatic 
  rise in sex hormone production. Remodeling was also evident within 