text: The participant reported for their MRI scan [3.0-T 
  Discovery MR750W (70-cm-wide bore), GE Medical] having 
  not completed any strenuous physical activity in (cid:2)24 h and 
  had received prior instruction to arrive in a relaxed state hav- 
  ing eaten and drunk normally. The participant sat quietly for 
  15 min prior to their scan. The participant lay supine for the 
  MRI scan of the lower-body musculature from T12 to the lat- 
  eral malleolus. A body coil (GE Medical) allowed axial T1- 
  weighted images (time of repetition/time to echo 600/8.144 
  ms, image matrix 512 (cid:3) 512, ﬁeld of view 500 (cid:3) 500 mm, 
  pixel size 0.9766 (cid:3) 0.9766 mm, slice thickness 5 mm, and 
  interslice gap 5 mm) to be acquired in ﬁve overlapping 
  blocks. Images of both sides of the body were acquired 
  within a single scan for blocks 1 (T12 to pelvis), 4 (knee joint 
  space to midshank), and 5 (midshank to lateral malleolus). 
  However, due to the size of the participant’s thighs, it was 
  necessary to scan each thigh individually for blocks 2 (pelvis 
  to midthigh) and 3 (midthigh to knee joint space); this 
  involved the radiographer repositioning the ﬁeld of view 
  between scanning the ﬁrst and the second thigh but not 
  physically moving the coil or the participant. Oil-ﬁlled cap- 
  sules were secured to the surface of the participant’s skin 
  with Transpore tape at intervals along the length of the lower 
  body prior to the scan and in an ofﬂine analysis used to ver- 
  ify the alignment of the blocks (Horos software, Version 3.36, 
  https://horosproject.org/). 