According to Travell's records, during his presidential years Kennedy suffered from high fevers; stomach, colon, and prostate issues; abscesses; high cholesterol; and adrenal problems. Travell kept a "Medicine Administration Record", cataloging Kennedy's medications: "injected and ingested corticosteroids for his adrenal insufficiency; procaine shots and ultrasound treatments and hot packs for his back; Lomotil, Metamucil, paregoric, phenobarbital, testosterone, and trasentine to control his diarrhea, abdominal discomfort, and weight loss; penicillin and other antibiotics for his urinary-tract infections and an abscess; and Tuinal to help him sleep."[19]

Family incidents
Main article: Kennedy curse
Kennedy's older brother Joseph P. Kennedy Jr. was killed in action in 1944 at age 29 when his plane exploded over the English Channel during a first attack execution of Operation Aphrodite during World War II.[401] His sister Rose Marie "Rosemary" Kennedy was born in 1918 with intellectual disabilities and underwent a prefrontal lobotomy at age 23, leaving her incapacitated until her death in 2005. Another sister Kathleen Agnes "Kick" Kennedy died in a plane crash en route to France in 1948. His wife Jacqueline Kennedy suffered a miscarriage in 1955 and a stillbirth in 1956: a daughter informally named Arabella.