Although the treaty called for ten more years of trade between the United States and the British Empire and gave American merchants guarantees that would have been good for business, Jefferson was unhappy that it did not end the hated British practice of impressment, and refused to give up the potential weapon of commercial warfare against Britain. The president made no attempt to obtain another treaty, and as a result, the two nations drifted from peace toward the War of 1812.[55] Monroe was severely pained by the administration's repudiation of the treaty, and he fell out with Secretary of State James Madison.[56]

1808 election and the Quids
On his return to Virginia in 1807, Monroe received a warm reception, and many urged him to run in the 1808 presidential election.[57] After Jefferson refused to submit the Monroe-Pinkney Treaty, Monroe had come to believe that Jefferson had snubbed the treaty out of the desire to avoid elevating Monroe above Madison in 1808.[58] Out of deference to Jefferson, Monroe agreed to avoid actively campaigning for the presidency, but he did not rule out accepting a draft effort.