where is the salivary glands located in the human body
wrapped around the mandibular ramus
1663762
saliva (salivation) is mediated by parasympathetic stimulation; acetylcholine is the active neurotransmitter and binds to muscarinic receptors in the glands, leading to increased salivation. The salivary glands are detailed below: The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. It is the serous type of gland which secretes alpha-amylase (also known as "ptyalin"). It enters the oral cavity via the parotid duct. The glands are located posterior to the mandibular ramus and
Salivary gland
1663762
saliva (salivation) is mediated by parasympathetic stimulation; acetylcholine is the active neurotransmitter and binds to muscarinic receptors in the glands, leading to increased salivation. The salivary glands are detailed below: The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. It is the serous type of gland which secretes alpha-amylase (also known as "ptyalin"). It enters the oral cavity via the parotid duct. The glands are located posterior to the mandibular ramus and
Salivary gland
2171035
Parotid gland The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands. Each parotid is wrapped around the mandibular ramus, and secretes serous saliva through the parotid duct into the mouth, to facilitate mastication and swallowing and to begin the digestion of starches. There are also two other types of salivary glands; they are submandibular and sublingual glands. The word "parotid" (paraotic) literally means "beside the ear". The parotid glands are
Parotid gland
20143594
Salivary microbiome The Salivary microbiome is the nonpathogenic, commensal bacteria present in the healthy human salivary glands. It is distinct from bacteria that may cause infection in the glands. It differs from the oral microbiome which is located in the oral cavity. Oral microorganisms tend to adhere to teeth. The oral microbiome possesses its own characteristic microorganisms found there. Resident microbes of the mouth adhere to the teeth and gums. "[T]here may be important interactions between the saliva microbiome and other microbiomes in the human body, in particular, that of the intestinal tract." Unlike the uterine, placental and vaginal microbiomes,
Salivary microbiome
1663771
salivary glands. Less than 100 genes are more specifically expressed in the salivary gland. The salivary gland specific genes are mainly genes that encode for secreted proteins and compared to other organs in the human body; the salivary gland has the highest fraction of secreted genes. The heterogeneous family of proline-rich, human salivary glycoproteins, such as PRB1 and PRH1, are salivary gland specific proteins with highest level of expression. Examples of other specifically expressed proteins include the digestive amylase enzyme AMY1A, the mucin MUC7 and statherin, all of major importance for specific characteristics of saliva. Aging of salivary glands show
Salivary gland
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These drain into ducts situated between the lobes of the gland (called interlobar ducts or secretory ducts). These are found on most major and minor glands (exception may be the sublingual gland). All of the human salivary glands terminate in the mouth, where the saliva proceeds to aid in digestion. The saliva that salivary glands release is quickly inactivated in the stomach by the acid that is present, however saliva also contains enzymes that are actually activated by stomach acid. About 20,000 protein coding genes are expressed in human cells and 60% of these genes are expressed in normal, adult
Salivary gland
13505111
which runs lengthwise through the body. The alimentary canal directs food unidirectionally from the mouth to the anus. It has three sections, each of which performs a different process of digestion. In addition to the alimentary canal, insects also have paired salivary glands and salivary reservoirs. These structures usually reside in the thorax, adjacent to the foregut. The salivary glands (element 30 in numbered diagram) in an insect's mouth produce saliva. The salivary ducts lead from the glands to the reservoirs and then forward through the head to an opening called the salivarium, located behind the hypopharynx. By moving its
Insect
18775120
the salivary glands, including cancer, may also occur within an accessory salivary gland tissue. "Salivary gland heterotopia" is where salivary gland acini cells are present in an abnormal location without any duct system. The most common location is the cervical lymph nodes. Other reported sites of heterotopic salivary gland tissue are the middle ear, parathyroid glands, thyroid gland, pituitary gland, cerebellar pontine angle, soft tissue medial to sternocleidomastoid, stomach, rectum and vulva. Salivary gland neoplasm occurrence within heterotopic salivary gland tissue is rare. Ectopic salivary gland tissue Ectopic salivary gland tissue which is located in sites other than the normal
Ectopic salivary gland tissue
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parotid submandibular, and sublingual. These glands secrete electrolytes, proteins, genetic material, polysaccharides, and other molecules. Most of these substances enter the salivary gland acinus and duct system from surrounding capillaries via the intervening tissue fluid, although some substances are produced within the glands themselves. The level of each salivary component varies considerably depending on the health status of the individual and the presence of pathogenic and commensal organisms. Salivary microbiome The Salivary microbiome is the nonpathogenic, commensal bacteria present in the healthy human salivary glands. It is distinct from bacteria that may cause infection in the glands. It differs from
Salivary microbiome
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tumours are very rare but if present, they are most likely to be malignant. In the United States, salivary gland cancers are uncommon with an incidence rate of 1.7 in 100000 between 2009 and 2013. Salivary gland tumour Salivary gland tumours or neoplasms are tumours that form in the tissues of salivary glands. The salivary glands are classified as major or minor. The major salivary glands consist of the parotid, submandibular, and sublingual glands. The minor salivary glands consist of 800-1000 small mucus-secreting glands located throughout the lining of the oral cavity. Salivary gland tumours usually present as a lump
Salivary gland tumour
11352559
Salivary gland tumour Salivary gland tumours or neoplasms are tumours that form in the tissues of salivary glands. The salivary glands are classified as major or minor. The major salivary glands consist of the parotid, submandibular, and sublingual glands. The minor salivary glands consist of 800-1000 small mucus-secreting glands located throughout the lining of the oral cavity. Salivary gland tumours usually present as a lump or swelling in the affected gland which may or may not have been present for a long time. The lump may be accompanied by symptoms of duct blockage (e.g. xerostomia). Usually, in their early stages
Salivary gland tumour
17550403
Parotidectomy A parotidectomy is the surgical excision (removal) of the parotid gland, the major and largest of the salivary glands. The procedure is most typically performed due to neoplasms (tumors), which are growths of rapidly and abnormally dividing cells. Neoplasms can be benign (non-cancerous) or malignant (cancerous). The majority of parotid gland tumors are benign, however 20% of parotid tumors are found to be malignant. A parotidectomy is performed mostly by the oral and maxillofacial surgeons and otolaryngologist. There are two parotid glands in the human body. Each parotid gland is located high in the neck just below the ears.
Parotidectomy
800849
glands contain a glandular portion and a duct portion, the structures of which can be used to classify the gland. Exocrine glands are named apocrine glands, holocrine glands, or merocrine glands based on how their products are secreted. Exocrine gland Exocrine glands are glands that produce and secrete substances onto an epithelial surface by way of a duct. Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, and mucous. Exocrine glands are one of two types of glands in the human body, the other being endocrine glands, which secrete their products directly into the bloodstream. The liver and
Exocrine gland
20143596
attributed to differences among human populations." "[E]nvironmental variables revealed a significant association between the genetic distances among locations and the distance of each location from the equator. Further characterization of the enormous diversity revealed here in the human salivary microbiome will aid in elucidating the role it plays in human health and disease, and in the identification of potentially informative species for studies of human population history." Sixty new genera have been identified from the salivary glands. A total of 101 different genera were identified in the salivary glands. Out of these, 39 genera are not found in the oral
Salivary microbiome
800848
Exocrine gland Exocrine glands are glands that produce and secrete substances onto an epithelial surface by way of a duct. Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, and mucous. Exocrine glands are one of two types of glands in the human body, the other being endocrine glands, which secrete their products directly into the bloodstream. The liver and pancreas are both exocrine and endocrine glands; they are exocrine glands because they secrete products—bile and pancreatic juice—into the gastrointestinal tract through a series of ducts, and endocrine because they secrete other substances directly into the bloodstream. Exocrine
Exocrine gland
4779002
glands may function abnormally or may not have developed at all because of inactive proteins in the sweat glands. Without normal sweat production, the body cannot regulate temperature properly. Therefore, overheating is a common problem, especially during hot weather. Access to cool environments is important. Several studies have examined salivary flow rate in individuals and found parotid and submandibular salivary flow ranging from 5 to 15 times lower than average. This is consistent with the salivary glands being of ectodermal origin, although some findings have suggested that there is also mesodermal input. The development of tooth buds frequently results in
Ectodermal dysplasia
17458535
Salivary gland pathology Salivary gland diseases (SGD) are multiple and varied in cause. There are 3 paired major salivary glands in humans (the parotid gland, the submandibular gland, and the sublingual gland), as well as about 800-1000 minor salivary glands in the oral mucosa of the mouth. The parotid gland is located in front of the ear, and it secretes its mostly serous saliva via the parotid duct (Stenson duct) into the mouth, usually opening roughly opposite the maxillary second molar. The submandibular gland is located medial to the angle of the mandible, and it drains its mixture of serous
Salivary gland pathology
648883
The digestive system consists of the mouth including the tongue and teeth, esophagus, stomach, (gastrointestinal tract, small and large intestines, and rectum), as well as the liver, pancreas, gallbladder, and salivary glands. It converts food into small, nutritional, non-toxic molecules for distribution and absorption into the body. The endocrine system consists of the principal endocrine glands: the pituitary, thyroid, adrenals, pancreas, parathyroids, and gonads, but nearly all organs and tissues produce specific endocrine hormones as well. The endocrine hormones serve as signals from one body system to another regarding an enormous array of conditions, and resulting in variety of changes
Human body
1663764
serous fluid and mucus, and enters the oral cavity via the submandibular duct or Wharton duct. Approximately 65-70% of saliva in the oral cavity is produced by the submandibular glands, even though they are much smaller than the parotid glands. This gland can usually be felt via palpation of the neck, as it is in the superficial cervical region and feels like a rounded ball. It is located about two fingers above the Adam's apple (laryngeal prominence) and about two inches apart under the chin. The sublingual glands are a pair of major salivary glands located inferior to the tongue,
Salivary gland
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the oral cavity saliva. The third pair are the sublingual glands located underneath the tongue and their secretion is mainly mucous with a small percentage of saliva. Within the oral mucosa, and also on the tongue, palates, and floor of the mouth, are the minor salivary glands; their secretions are mainly mucous and they are innervated by the facial nerve (CN7). The glands also secrete amylase a first stage in the breakdown of food acting on the carbohydrate in the food to transform the starch content into maltose. There are other glands on the surface of the tongue that encircle
Human digestive system
13618374
feeling); the peroxides are neutralized through the production of glutathione from selenium. In turn, an excess of selenium increases demand for iodine, and deficiency will result when a diet is high in selenium and low in iodine. The human body contains about 15–20 mg of iodine, mostly concentrated in thyroid tissue (70–80%). Extra-thyroidal iodine exists in several other organs, including the mammary glands, eyes, gastric mucosa, cervix, ovary and salivary glands. In the cells of these tissues the iodide ion (I) enters directly by the sodium-iodide symporter (NIS). Different tissue responses for iodine and iodide occur in the mammary glands
Iodine in biology
1663763
anterior to the mastoid process of the temporal bone. They are clinically relevant in dissections of facial nerve branches while exposing the different lobes, since any iatrogenic lesion will result in either loss of action or strength of muscles involved in facial expression. They produce 20% of the total salivary content in the oral cavity. Mumps is a viral infection, caused by infection in the parotid gland. The submandibular glands (previously known as submaxillary glands) are a pair of major salivary glands located beneath the lower jaws, superior to the digastric muscles. The secretion produced is a mixture of both
Salivary gland
4559540
Parotitis Parotitis is an inflammation of one or both parotid glands, the major salivary glands located on either side of the face, in humans. The parotid gland is the salivary gland most commonly affected by inflammation. "Dehydration:" This is a common, non-infectious cause of parotitis. It may occur in elderly or after surgery. "Acute bacterial parotitis:" is most often caused by a bacterial infection of Staphylococcus aureus but may be caused by any commensal bacteria. Parotitis presents as swelling at the angle of the jaw. Bacterial parotitis presents as a unilateral swelling, where the gland is swollen and tender and
Parotitis
1663761
Salivary gland The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual) as well as hundreds of minor salivary glands. Salivary glands can be classified as serous, mucous or seromucous (mixed). In serous secretions, the main type of protein secreted is alpha-amylase, an enzyme that breaks down starch into maltose and glucose, whereas in mucous secretions the main protein secreted is mucin, which acts as a lubricant. In humans, between 0.5 and 1.5 litres of saliva are produced every day. The secretion of
Salivary gland
3916753
are present in swamps and rivers, where human activities such as farming, fishing, and bathing take place. Present findings describing the experimental transmission of "M. ulcerans" from water bugs to mice are in good agreement with the possibility of this mode of transmission to humans by bites. Also in strong support of this hypothesis was the localization of "M. ulcerans" within the salivary glands of Naucoridae. Local physiological conditions of this niche appear to fit the survival and the replication needs of "M. ulcerans" but not those of other mycobacteria. Surprisingly, infiltration of the salivary glands of Naucoridae by "M.
Buruli ulcer
11161386
a high risk of diabetes side-effects. These drugs potently bind to and block the muscarinic M receptor, which causes insulin dysregulation that may precede diabetes. The M receptors are also located in many glands, both endocrine and exocrine glands, and help to stimulate secretion in salivary glands and other glands of the body. Other effects are: No highly selective M3 agonists are yet available as of 2018, but a number of non-selective muscarinic agonists are active at M3. Muscarinic acetylcholine receptor M3 has been shown to pre-couple with Gq proteins. The polybasic c-tail of the receptor is necessary for the
Muscarinic acetylcholine receptor M3
1663778
in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of venomous snakes , Gila monsters, and some shrews, are actually modified salivary glands. In other organisms such as insects, salivary glands are often used to produce biologically important proteins like silk or glues, whilst fly salivary glands contain polytene chromosomes that have been useful in genetic research. Salivary gland The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual) as well as
Salivary gland
1663765
anterior to the submandibular glands. The secretion produced is mainly mucous in nature; however, it is categorized as a mixed gland. Unlike the other two major glands, the ductal system of the sublingual glands does not have intercalated ducts and usually does not have striated ducts either, so saliva exits directly from 8-20 excretory ducts known as the Rivinus ducts. Approximately 5% of saliva entering the oral cavity comes from these glands. There are 800 to 1,000 minor salivary glands located throughout the oral cavity within the submucosa of the oral mucosa in the tissue of the buccal, labial, and
Salivary gland
18773813
HIV salivary gland disease Human immunodeficiency virus salivary gland disease (abbreviated to HIV-SGD, and also termed HIV-associated salivary gland disease), is swelling of the salivary glands and/or xerostomia in individuals infected with human immunodeficiency virus. HIV-SGD may be the presenting sign of HIV infection. There may also be xerophthalmia (dry eyes) and arthralgia (joint pain), similar to Sjögren syndrome. HIV-SGD is more prevalent in HIV positive children than HIV positive adults, at about 19% and 1% respectively. Unlike other oral manifestations of HIV/AIDS such as Kaposi sarcoma, oral hairy leukoplakia and oral candidiasis, which decreased following the introduction of highly
HIV salivary gland disease
18773814
active antiretroviral therapy (HAART), HIV-SGD has increased. HIV salivary gland disease Human immunodeficiency virus salivary gland disease (abbreviated to HIV-SGD, and also termed HIV-associated salivary gland disease), is swelling of the salivary glands and/or xerostomia in individuals infected with human immunodeficiency virus. HIV-SGD may be the presenting sign of HIV infection. There may also be xerophthalmia (dry eyes) and arthralgia (joint pain), similar to Sjögren syndrome. HIV-SGD is more prevalent in HIV positive children than HIV positive adults, at about 19% and 1% respectively. Unlike other oral manifestations of HIV/AIDS such as Kaposi sarcoma, oral hairy leukoplakia and oral candidiasis,
HIV salivary gland disease
722401
intestine that terminates in a cloaca on the posterior dorsal surface of the animal. Up to seven salivary glands are present in some species, emptying to the mouth in front of the oesophagus, while the stomach is associated with two gastric glands that produce digestive enzymes. A pair of protonephridia open into a bladder that drains into the cloaca. These organs expel water from the body, helping to maintain osmotic balance. Rotifers have a small brain, located just above the mastax, from which a number of nerves extend throughout the body. The number of nerves varies among species, although the
Rotifer
3308900
with respect to vasculature, activation of M on vascular endothelial cells causes increased synthesis of nitric oxide, which diffuses to adjacent vascular smooth muscle cells and causes their relaxation, thereby explaining the paradoxical effect of parasympathomimetics on vascular tone and bronchiolar tone. Indeed, direct stimulation of vascular smooth muscle, M mediates vasconstriction in pathologies wherein the vascular endothelium is disrupted. The M receptors are also located in many glands, which help to stimulate secretion in, for example, the salivary glands, as well as other glands of the body. Like the M muscarinic receptor, M receptors are G proteins of class
Muscarinic acetylcholine receptor
16530356
forehead glands (located on the forehead), the preorbital glands (located below the eyes), the nasal glands (located inside the nostrils), the interdigital glands (located between the toes), the preputial gland (located inside the foreskin of the deer's penis), the metatarsal glands (located outside of the hind legs), and the tarsal glands (located inside of the hind legs). Though it is not their primary function, the salivary glands also function as scent glands. Deer rely heavily on these scent glands to communicate with other members of their species, and possibly even with members of other species. A deer may rub its
Preorbital gland
5292880
15–20 mg of iodine in the human body which is primarily concentrated in thyroid tissue and hormones, but 30% of iodine is distributed in other tissues, including mammary glands, eyes, gastric mucosa, choroid plexus, arterial walls, the cervix, and salivary glands. In the cells of these tissues, iodide enters directly by sodium-iodide symporter (NIS). The diagnostic workup of a suspected iodine deficiency includes signs and symptoms as well as possible risk factors mentioned above. A 24-hour urine iodine collection is a useful medical test, as approximately 90% of ingested iodine is excreted in the urine. For the standardized 24-hour test,
Iodine deficiency
3889206
Digestive enzyme Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body. Digestive enzymes are found in the digestive tracts of animals (including humans) and in the traps of carnivorous plants, where they aid in the digestion of food, as well as inside cells, especially in their lysosomes, where they function to maintain cellular survival. Digestive enzymes of diverse specificities are found in the saliva secreted by the salivary glands, in the secretions of cells lining In the human digestive system, the main sites
Digestive enzyme
3889211
these enzymes include: Digestive enzyme Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body. Digestive enzymes are found in the digestive tracts of animals (including humans) and in the traps of carnivorous plants, where they aid in the digestion of food, as well as inside cells, especially in their lysosomes, where they function to maintain cellular survival. Digestive enzymes of diverse specificities are found in the saliva secreted by the salivary glands, in the secretions of cells lining In the human digestive system,
Digestive enzyme
1430916
small molecules the body can use. In the human digestive system, food enters the mouth and mechanical digestion of the food starts by the action of mastication (chewing), a form of mechanical digestion, and the wetting contact of saliva. Saliva, a liquid secreted by the salivary glands, contains salivary amylase, an enzyme which starts the digestion of starch in the food; the saliva also contains mucus, which lubricates the food, and hydrogen carbonate, which provides the ideal conditions of pH (alkaline) for amylase to work. After undergoing mastication and starch digestion, the food will be in the form of a
Digestion
9351684
Human cytomegalovirus Human cytomegalovirus is a species of the virus genus "Cytomegalovirus", which in turn is a member of the viral family known as "Herpesviridae" or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within "Herpesviridae", HCMV belongs to the "Betaherpesvirinae" subfamily, which also includes cytomegaloviruses from other mammals. Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ
Human cytomegalovirus
16016283
colleagues shows that outcomes for testosterone, DHEA, progesterone, and estradiol biomarkers are elevated when cotton-based collection materials are used as opposed to samples collected by other methods (i.e. passive drool). Researchers are currently examining the expanding role of saliva testing as part of routine dental or medical office examinations where saliva collection is simple to perform. Humans have three major salivary glands: parotid, submandibular, and sublingual. These glands, along with additional minor salivary glands, secrete a rich mixture of biological chemicals, electrolytes, proteins, genetic material, polysaccharides, and other molecules. Most of these substances enter the salivary gland acinus and duct
Saliva testing
11319434
pancreas, esophagus, duodenum, salivary glands, fallopian tube, corpus uteri, bulbourethral glands and cervix. This list corresponds closely to the sites from which all late onset cancers develop. MSMB is a rapidly evolving protein. Solution structures of human and porcine MSMB show remarkable similarity despite having only 51% of amino acids in common. The C-terminus domain of MSMB contains two two-stranded β-sheets; these have no resemblance to other structural motifs. The rapid evolution of MSMB can be attributed to either sexual selection or innate pathogen defense; the wide distribution of MSMB in the body and the fungicidal properties of the C-terminus
MSMB
17916229
Human digestive system The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body. The process of digestion has many stages. The first stage is the cephalic phase of digestion which begins with gastric secretions in response to the sight and smell of food. The next stage starts in the mouth. Chewing, in which food is mixed with saliva, begins the mechanical process of digestion. This produces
Human digestive system
1663775
by decreasing clotting time and increasing wound contraction. Saliva contains the enzyme amylase, which hydrolyses starch into maltose and dextrin. As a result, saliva allows digestion to occur before the food reaches the stomach. Saliva acts as a solvent in which solid particles can dissolve in and enter the taste buds through oral mucosa located on the tongue. These taste buds are found within foliate and circumvallate papillae, where minor salivary glands secrete saliva. A sialolithiasis (a salivary calculus or stone) may cause blockage of the ducts, most commonly the submandibular ducts, causing pain and swelling of the gland. Salivary
Salivary gland
12419628
constantly circulates the oral cavity, is capable of impacting both the remineralisation and demineralisation processes. It is secreted through the major salivary glands including the parotid, submandibular, sublingual and Von Ebner's glands as well as the hundreds of minor salivary glands that are located throughout the oral cavity. Remineralization occurs on a daily basis after an acidogenic challenge through the presence of saliva. Calcium, phosphate and fluoride found in saliva, are required for effective remineralization and maintenance of the enamel surface integrity. Therefore, as saliva is rich in calcium and phosphate ions, it can act as a natural buffer to
Remineralisation of teeth
5500367
The trypomastigotes enter the midgut of the fly where they become procyclic trypomastigotes. These rapidly divide to become epimastigotes. The epimastigotes migrate from the gut via the proventriculus to the salivary glands where they get attached to the salivary gland epithelium. In the salivary glands, some parasites detach and undergo transformation into short and stumpy trypomastigotes. These become the infective metacyclic trypomastigotes. They are injected into the mammalian host along with the saliva on biting. Complete development in the fly takes about 20 days. The reproduction of "T. brucei" is unusual compared to most eukaryotes. The nuclear membrane remains intact
Trypanosoma brucei
5496982
many hundreds to a few thousand. Eventually, the oocyst ruptures and the sporozoites are released into the hemocoel of the mosquito. The sporozoites are then carried by the circulation of the hemolymph to the salivary glands, where they become concentrated in the acinal cells. A small number of sporozoites are introduced into the salivary duct and injected into the venules of the bitten human. This initiates the cycle in the human liver. The ring stages that are formed by the invasion of merozoites released by rupturing liver stage schizonts are the first stages that appear in the blood. The ring
Plasmodium malariae
17916242
starts to work on breaking down fats. Lipase is further produced in the pancreas where it is released to continue this digestion of fats. The presence of salivary lipase is of prime importance in young babies whose pancreatic lipase has yet to be developed. As well as its role in supplying digestive enzymes, saliva has a cleansing action for the teeth and mouth. It also has an immunological role in supplying antibodies to the system, such as immunoglobulin A. This is seen to be key in preventing infections of the salivary glands, importantly that of parotitis. Saliva also contains a
Human digestive system
783699
small intestine, and large intestine. However, the complete human digestive system is made up of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver and gallbladder). The tract may also be divided into foregut, midgut, and hindgut, reflecting the embryological origin of each segment. The whole human GI tract is about nine metres (30 feet) long at autopsy. It is considerably shorter in the living body because the intestines, which are tubes of smooth muscle tissue, maintain constant muscle tone in a halfway-tense state but can relax in spots to allow for local distention
Gastrointestinal tract
2171042
and to enable bacterial clearance from the mouth. The parotid salivary glands appear early in the sixth week of prenatal development and are the first major salivary glands formed. The epithelial buds of these glands are located on the inner part of the cheek, near the labial commissures of the primitive mouth (from ectodermal lining near angles of the stomodeum in the 1st/2nd pharyngeal arches; the stomodeum itself is created from the rupturing of the oropharyngeal membrane at about 26 days.) These buds grow posteriorly toward the otic placodes of the ears and branch to form solid cords with rounded
Parotid gland
1648749
initiation of swallowing, and protecting the mucosal surfaces of the oral cavity from desiccation. Various animal species have special uses for saliva that go beyond predigestion. Some swifts use their gummy saliva to build nests. "Aerodramus" nests form the basis of bird's nest soup. Cobras, vipers, and certain other members of the venom clade hunt with venomous saliva injected by fangs. Some caterpillars produce silk fiber from salivary glands. Produced in salivary glands, human saliva is 99.5% water, but also contains many important substances, including electrolytes, mucus, antibacterial compounds and various enzymes. There is much debate about the amount of
Saliva
3809298
Sublingual gland The paired sublingual glands are major salivary glands in the mouth. They are the smallest, most diffuse, and the only unencapsulated major salivary glands. They provide only 3-5% of the total salivary volume. There are also two other types of salivary glands; they are submandibular and Parotid glands. They lie anterior and superior to the submandibular gland and inferior and lateral to the tongue, as well as beneath the mucous membrane of the floor of the mouth. They are bounded laterally by the bone of the mandible and inferolaterally by the mylohyoid muscle. The glands can be felt
Sublingual gland
3809302
developing submandibular gland. These buds branch and form into cords that canalize to form the sublingual ducts associated with the gland. The rounded terminal ends of the cords form acini. Ranulas are the most common pathologic lesion associated with the sublingual glands. Sublingual gland The paired sublingual glands are major salivary glands in the mouth. They are the smallest, most diffuse, and the only unencapsulated major salivary glands. They provide only 3-5% of the total salivary volume. There are also two other types of salivary glands; they are submandibular and Parotid glands. They lie anterior and superior to the submandibular
Sublingual gland
796722
nuclear egress, and budding. Human and monkeys serve as the natural host. Transmission routes are contact, urine, and saliva. All herpesviruses share a characteristic ability to remain latent within the body over long periods. Although they may be found throughout the body, CMV infections are frequently associated with the salivary glands in humans and other mammals. The CMV promoter is commonly included in vectors used in genetic engineering work conducted in mammalian cells, as it is a strong promoter and drives constitutive expression of genes under its control. Cytomegalovirus was first observed by German pathologist Hugo Ribbert in 1881 when
Cytomegalovirus
17916294
predispose for certain digestive disorders. Gestational diabetes can develop in the mother as a result of pregnancy and while this often presents with few symptoms it can lead to pre-eclampsia. Human digestive system The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body. The process of digestion has many stages. The first stage is the cephalic phase of digestion which begins with gastric secretions in response
Human digestive system
17916238
glands, all of which mainly serve the digestive process, and also play an important role in the maintenance of dental health and general mouth lubrication, without which speech would be impossible. The main glands are all exocrine glands, secreting via ducts. All of these glands terminate in the mouth. The largest of these are the parotid glands—their secretion is mainly serous. The next pair are underneath the jaw, the submandibular glands, these produce both serous fluid and mucus. The serous fluid is produced by serous glands in these salivary glands which also produce lingual lipase. They produce about 70% of
Human digestive system
11316193
the kidney tubular epithelia, the respiratory airway, the female reproductive tract, testis, including, spermatogonia in the seminiferous tubules, Sertoli cells, and spermatoozoa, colon and salivary glands. In the skin, SCNN1A is expressed in the keratinocytes in the epidermal layer, in the sebaceous sweat glands, and the smooth muscle cells mostly within the cytoplasm. In contrast, in the eccrine sweat glands ENaC is mostly located on the luminal surface of eccrine duct epithelia. ENaC is also expressed in the tongue, where it has been shown to be essential for the perception of salt taste. The expression of ENaC subunit genes is
SCNN1A
7206551
and have also described the salivary glands as an in vivo reservoir for HHV-6. The virus infects the salivary glands, establishes latency, and periodically reactivates to spread infection to other hosts. Vertical transmission has also been described, and occurs in approximately 1% of births in the United States. This form is easily identifiable as the viral genome is contained within every cell of an infected individual. Examination of a series of tonsils with Western blotting gave a 100% detection rate for HHV-6. The classical presentation of primary HHV-6b infection is as exanthema subitum (ES) or "roseola", featuring a high temperature
Human herpesvirus 6
12290096
Sialoendoscopy Sialoendoscopy (commonly referred to as Sialendoscopy) is a minimally invasive technique that allows for salivary gland surgery for the safe and effective treatment of obstructive salivary gland disorders and other conditions of the salivary glands. During sialoendoscopy a small endoscope is placed into the salivary glands through the salivary ducts that empty into the mouth. Sialoendoscopy is an efficient yet simple mode of treatment for major salivary gland obstructions, strictures and sialoliths (salivary stones). Depending on the obstruction, sialoendoscopy can be conducted under local anesthesia in an outpatient office or in the operating room under general anesthesia. Salivary gland
Sialoendoscopy
15488571
Salivary gland–like carcinoma of the lung Salivary gland–like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell division (mitosis) of mutated cancer stem cells in lung tissue. They take their name partly from the appearance of their abnormal cells, whose structure and features closely resemble those of cancers that form in the major salivary glands (parotid glands, submandibular glands and sublingual glands) of the head and neck. Carcinoma is a term for malignant neoplasms derived from cells of epithelial lineage, and/or that exhibit cytological or tissue architectural features characteristically found in epithelial
Salivary gland–like carcinoma of the lung
5495258
divides repeatedly to form large number of daughter nuclei. At the same time, the cytoplasm develops large vacuoles and forms numerous cytoplasmic masses. These cytoplasmic masses then elongate and a daughter nuclei migrates into each mass. The resulting sickle-shaped bodies are known as sporozoites. This phase of asexual multiplication is known as sporogony and is completed in about 10–21 days. The oocyst then bursts and sporozoites are released into the body cavity of mosquito. Sporozoites eventually reach the salivary glands of mosquito via its hemolymph. The mosquito now becomes infectious. Salivary glands of a single infected mosquito may contain as
Plasmodium vivax
12684413
sweat glands, salivary and mammary glands, thymus, lymph nodes, biliary tract, kidney, liver, placenta, uterus, prostate, skin, and the capillary bed of the gut mucosa (where most GLP-1 is inactivated locally). It is also present, in soluble form, in body fluids, such as blood plasma and cerebrospinal fluid. (It also happens that DPP-4 is the CD26 T-cell activating antigen.) DPP-4 selectively cleaves two amino acids from peptides, such as GLP-1 and GIP, which have proline or alanine in the second position ("Figure 2"). At the active site where DPP-4 has its effect, there is a characteristic arrangement of three amino
Discovery and development of dipeptidyl peptidase-4 inhibitors
18757004
of the mouth, and upper respiratory tract infections (e.g., candidiasis, ascending sialadenitis, laryngitis and pharyngitis). Patients with salivary gland aplasia typically require regular application of topical fluoride to prevent tooth decay. Salivary gland aplasia Salivary gland aplasia (also termed salivary gland agenesis) is the congenital absence of salivary glands. Usually the term relates to the absence of some or all of the major salivary glands. It is a rare condition, and most known cases have been in association with syndromes of the ectodermal tissues, particularly the lacrimal apparatus. Example syndromes which have been reported with salivary gland aplasia include hereditary
Salivary gland aplasia
1663777
therapy may impair salivary flow. Radiotherapy can cause permanent hyposalivation due to injury to the oral mucosa containing the salivary glands, resulting in xerostomia, whereas chemotherapy may cause only temporary salivary impairment. Graft versus host disease after allogeneic bone marrow transplantation may manifest as dry mouth and many small mucoceles. Salivary gland tumours may occur, including mucoepidermoid carcinoma, a malignant growth. A sialogram is a radiocontrast study of a salivary duct that may be used to investigate its function and for diagnosing Sjögren syndrome. The salivary glands of some species are modified to produce proteins - salivary amylase is found
Salivary gland
18780561
caused by an allergic reaction, in which there is sudden swelling of the salivary glands. It is associated with other allergic conditions such as asthma, urticaria, allergic rhinitis and food allergy. Sialodochitis Sialodochitis (also termed ductal sialadenitis), is inflammation of the duct system of a salivary gland. This is compared to sialadenitis, which is inflammation of the gland parenchyma. Sialodochitis may be associated with salivary duct strictures and salivary stones. It is common in both the parotid glands and submandibular glands. The treatment is as for sialadenitis. It may appear on a CT scan or MRI scan as enhancement and
Sialodochitis
17916230
a bolus which can be swallowed down the esophagus to enter the stomach. Here it is mixed with gastric acid until it passes into the duodenum where it is mixed with a number of enzymes produced by the pancreas. Saliva also contains a catalytic enzyme called amylase which starts to act on food in the mouth. Another digestive enzyme called lingual lipase is secreted by some of the lingual papillae on the tongue and also from serous glands in the main salivary glands. Digestion is helped by the chewing of food carried out by the muscles of mastication, by the
Human digestive system
12290101
the surgeon. Sialoendoscopy Sialoendoscopy (commonly referred to as Sialendoscopy) is a minimally invasive technique that allows for salivary gland surgery for the safe and effective treatment of obstructive salivary gland disorders and other conditions of the salivary glands. During sialoendoscopy a small endoscope is placed into the salivary glands through the salivary ducts that empty into the mouth. Sialoendoscopy is an efficient yet simple mode of treatment for major salivary gland obstructions, strictures and sialoliths (salivary stones). Depending on the obstruction, sialoendoscopy can be conducted under local anesthesia in an outpatient office or in the operating room under general anesthesia.
Sialoendoscopy
18757003
Salivary gland aplasia Salivary gland aplasia (also termed salivary gland agenesis) is the congenital absence of salivary glands. Usually the term relates to the absence of some or all of the major salivary glands. It is a rare condition, and most known cases have been in association with syndromes of the ectodermal tissues, particularly the lacrimal apparatus. Example syndromes which have been reported with salivary gland aplasia include hereditary ectodermal dysplasia, mandibulofacial dysostosis and hemifacial microsomia. The main significance of the condition is a lack of saliva, causing xerostomia (dry mouth), with accompanying susceptibility to dental caries (tooth decay), infections
Salivary gland aplasia
11123247
IL-1 β in human mesangial cells. MMP7 are commonly expressed in epithelial cells including ductal epithelium of exocrine glands in skin, salivary glands, pancreas, glandular epithelium of intestine and reproductive organ, liver, and breast. In addition, MMP7 is highly expressed in the luminal surface of dysplastic glands in human colorectal cancers. A MMP7 protein is bounded by four metal ions including a catalytic zinc ion, a structural zinc ion, and two calcium ions. The catalytic zinc ion binds to three His residues in the HEXGHXXGXXH region in tetracoordination. The calcium ion binding play important role in stabilizing the secondary structure.
MMP7
1663767
saliva. Problems with dentures are sometimes associated with minor salivary glands if there is dry mouth present (see further discussion). The minor salivary glands are innervated by the seventh cranial or facial nerve. Von Ebner's glands are glands found in a trough circling the circumvallate papillae on the dorsal surface of the tongue near the terminal sulcus. They secrete a purely serous fluid that begins lipid hydrolysis. They also facilitate the perception of taste through secretion of digestive enzymes and proteins. The arrangement of these glands around the circumvallate papillae provides a continuous flow of fluid over the great number
Salivary gland
708050
use when the test is taken. A slit-lamp examination can reveal dryness on the surface of the eye. Symptoms of dry mouth and dryness in the oral cavity are caused by the reduced production of saliva from the salivary glands (parotid gland, submandibular gland, and sublingual gland). To check the status of salivary glands and the production of saliva, a salivary flow-rate test is performed, in which the person is asked to spit as much as they can into a cup, and the resulting saliva sample is collected and weighed. This test's results can determine whether the salivary glands are
Sjögren syndrome
17458538
trauma. Congenital disorders of the salivary glands are rare, but may include: Infections involving the salivary glands can be viral or bacterial (or rarely fungal). A salivary diverticulum (plural "diverticuli") is a small pouch or out-pocketing of the duct system of a major salivary gland. Such diverticuli typically cause pooling of saliva and recurrent sialadenitis, especially parotitis. A diverticulum may also cause a sialolith to form. The condition can be diagnosed by sialography. Affected individuals may "milk" the salivary gland to encourage flow of saliva through the duct. Salivary gland pathology Salivary gland diseases (SGD) are multiple and varied in
Salivary gland pathology
8096792
the general population. Sialolithiasis accounts for about 50% of all disease occurring in major salivary glands, and for about 66% of all obstructive salivary gland diseases. Salivary gland stones are twice as common in males as in females. The most common age range in which they occur is between 30 and 60, and they are uncommon in children. Sialolithiasis Sialolithiasis (also termed salivary calculi, or salivary stones), is a condition where a calcified mass or "sialolith" forms within a salivary gland, usually in the duct of the submandibular gland (also termed "Wharton's duct"). Less commonly the parotid gland or rarely
Sialolithiasis
13699554
or frons. The clypeus, located below the frons, lies between the two antennae. The labrum is found below the clypeus. There is a small notch in the centre of the labrum with which the leaf edge engages when the caterpillar eats. The larvae have silk glands which are located on the labium. These glands are modified salivary glands. They use these silk glands to make silk for cocoons and shelters. Located below the labrum are the mandibles. On each side of the head there are usually six stemmata just above the mandibles. These stemmata are arranged in a semicircle. Below
External morphology of Lepidoptera
6565120
based around two main concerns. The first is that the method of removal could cause further injection of noxious substances (allergens, paralysing toxins and infectious micro-organisms). The second is that the method may leave the 'head' (really just the tick's mouthparts) embedded in the skin. The tick's salivary glands and gut contents are together the main source of the noxious substances and these are located in the main body of the tick. It is thought that any irritation of the tick might cause it to either inject saliva or regurgitate gut contents or that any compression the body of the
Ixodes holocyclus
3889207
of digestion are the oral cavity, the stomach, and the small intestine. Digestive enzymes are secreted by different exocrine glands including: Complex food substances that are taken by animals and humans must be broken down into simple, soluble, and diffusible substances before they can be absorbed. In the oral cavity, salivary glands secrete an array of enzymes and substances that aid in digestion and also disinfection. They include the following: Of note is the diversity of the salivary glands. There are two types of salivary glands: The enzymes that are secreted in the stomach are "gastric enzymes". The stomach plays
Digestive enzyme
8948851
and soft palate. However, the condition may arise anywhere minor salivary glands are located. It has also been occasionally reported to involve the major salivary glands. It may be present only on one side, or both sides. The lesion typically is 1–4 cm in diameter. Initially, the lesion is a tender, erythematous (red) swelling. Later, in the ulcerated stage, the overlying mucosa breaks down to leave a deep, well-circumscribed ulcer which is yellow-gray in color and has a lobular base. There is usually only minor pain, and the condition is often entirely painless. There may be prodromal symptoms similar to
Necrotizing sialometaplasia
4559554
masseteric hypertrophy is still unclear, but it may be related to tooth grinding or malocclusion. Treatment options can include surgical removal of some of the muscle and botulinum toxin type A injections. Serum and urinary amylase are raised during first week of parotitis Treatment is based on lab investigation report,but for relief you can suggest to patient,take anti-inflammatory tablet, antibiotics. Parotitis Parotitis is an inflammation of one or both parotid glands, the major salivary glands located on either side of the face, in humans. The parotid gland is the salivary gland most commonly affected by inflammation. "Dehydration:" This is a
Parotitis
10579724
food and fluid movement between three regions. The three regions include the foregut (stomatodeum)(27,) the midgut (mesenteron)(13), and the hindgut (proctodeum)(16). In addition to the alimentary canal, insects also have paired salivary glands and salivary reservoirs. These structures usually reside in the thorax (adjacent to the fore-gut). The salivary glands (30) produce saliva; the salivary ducts lead from the glands to the reservoirs and then forward through the head to an opening called the salivarium behind the hypopharynx; which movements of the mouthparts help mix saliva with food in the buccal cavity. Saliva mixes with food, which travels through salivary
Insect physiology
8850427
Mucous gland Mucous gland, also known as muciparous glands, are found in several different parts of the body, and they typically stain lighter than serous glands during standard histological preparation. Most are multicellular, but goblet cells are single-celled glands. The mucous salivary glands are similar in structure to the buccal and labial glands. They are found especially at the back part behind the vallate papillae, but are also present at the apex and marginal parts. In this connection the anterior lingual glands require special notice. They are situated on the under surface of the apex of the tongue, one on
Mucous gland
4304069
Adenoid cystic carcinoma Adenoid cystic carcinoma (sometimes referred to as adenocyst, malignant cylindroma, adenocystic, adenoidcystic, ACC or AdCC.) is a rare type of cancer that can exist in many different body sites. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, lacrimal gland, lung, brain, bartholin gland, trachea, and the paranasal sinuses. It is the third-most common malignant salivary gland tumor overall (after mucoepidermoid carcinoma and polymorphous adenocarcinoma). It represents 28% of malignant submandibular gland tumors, making it the single most common malignant salivary gland tumor in
Adenoid cystic carcinoma
4304073
are ongoing, however. Adenoid cystic carcinoma Adenoid cystic carcinoma (sometimes referred to as adenocyst, malignant cylindroma, adenocystic, adenoidcystic, ACC or AdCC.) is a rare type of cancer that can exist in many different body sites. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, lacrimal gland, lung, brain, bartholin gland, trachea, and the paranasal sinuses. It is the third-most common malignant salivary gland tumor overall (after mucoepidermoid carcinoma and polymorphous adenocarcinoma). It represents 28% of malignant submandibular gland tumors, making it the single most common malignant salivary
Adenoid cystic carcinoma
4559551
any of the major salivary glands, i.e. parotid or submandibular glands. This is often symmetrical and is usually associated with manifestations of IgG4-RD elsewhere in the body. IgG4-related sialadenitis is particularly associated with involvement of one or both of the lacrimal glands (referred to as IgG4-related dacryo-sialadenitis). "Mikulicz's disease", now considered to be a subtype of IgG4-related disease, was a term used when (i) any two of the parotid, submandibular and lacrimal glands were persistently and symmetrically enlarged and (ii) other diseases that may mimic this presentation were excluded. "Pneumoparotitis:" Air within the ducts of the parotid gland with or
Parotitis
5637244
Scent gland Scent glands are exocrine glands found in most mammals. They produce semi-viscous secretions which contain pheromones and other semiochemical compounds. These odor-messengers indicate information such as status, territorial marking, mood, and . The odor may be subliminal—not consciously detectable. Though it is not their primary function, the salivary glands may also function as scent glands in some animals. The even-toed ungulates (Artiodactyla) have many specialized skin glands, the secretions of which are involved in semiochemical communication. These glands include the sudoriferous glands (located on the forehead, between the antlers and eyes), the preorbital glands (extending from the medial
Scent gland
5637249
Like the herpestids, it has no prescrotal glands. Scent gland Scent glands are exocrine glands found in most mammals. They produce semi-viscous secretions which contain pheromones and other semiochemical compounds. These odor-messengers indicate information such as status, territorial marking, mood, and . The odor may be subliminal—not consciously detectable. Though it is not their primary function, the salivary glands may also function as scent glands in some animals. The even-toed ungulates (Artiodactyla) have many specialized skin glands, the secretions of which are involved in semiochemical communication. These glands include the sudoriferous glands (located on the forehead, between the antlers and
Scent gland
17458536
and mucous saliva via the submandibular duct (Wharton duct) into the mouth, usually opening in a punctum located in the floor of mouth. The sublingual gland is located below the tongue, in the floor of the mouth. It drains its mostly mucous saliva into the mouth via about 8-20 ducts which open along the plica sublingualis (a fold of tissue under the tongue). The function of the salivary glands is to secrete saliva, which has a lubricating function, which protects the oral mucosa of the mouth during eating and speaking. Saliva also contains digestive enzymes (e.g. salivary amylase) and has
Salivary gland pathology
8036604
Sialadenitis Sialadenitis (sialoadenitis) is inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. It should not be confused with sialadenosis (sialosis) which is a non-inflammatory enlargement of the major salivary glands. Sialadenitis can be further classed as acute or chronic. Acute sialadenitis is an acute inflammation of a salivary gland which may present itself as a red, painful swelling that is tender to touch. Chronic sialadenitis is typically less painful but presents as recurrent swellings, usually after meals, without redness. Causes of sialadenitis are varied, including bacterial (most
Sialadenitis
119347
endocrine glands are, in general, their ductless nature, their vascularity, and commonly the presence of intracellular vacuoles or granules that store their hormones. In contrast, exocrine glands, such as salivary glands, sweat glands, and glands within the gastrointestinal tract, tend to be much less vascular and have ducts or a hollow lumen. A number of glands that signal each other in sequence are usually referred to as an axis, for example, the hypothalamic-pituitary-adrenal axis. In addition to the specialized endocrine organs mentioned above, many other organs that are part of other body systems, such as bone, kidney, liver, heart and
Endocrine system
3107847
the formation of more acini. Lateral to both sides of the tongue, a linear groove develops and closes over to form the submandibular duct. The submandibular gland accounts for 80% of all salivary duct calculi (salivary stones or sialolith), possibly due to the different nature of the saliva that it produces and the tortuous travel of the submandibular duct to its ductal opening for a considerable upward distance. The submandibular gland is one of the major three glands that provide the mouth with saliva. The two other types of salivary glands are parotid and sublingual glands. Submandibular gland The paired
Submandibular gland
3107845
The submandibular gland's highly active acini account for most of the salivary volume. The parotid and sublingual glands account for the remaining. The gland receives its blood supply from the facial and lingual arteries. The gland is supplied by sublingual and submental arteries and drained by common facial and lingual veins. The lymphatics from submandibular gland first drain into submandibular lymph nodes and subsequently into jugulo - digastric lymph nodes. Their secretions, like the secretions of other salivary glands, are regulated "directly" by the parasympathetic nervous system and "indirectly" by the sympathetic nervous system. The submandibular salivary glands develop later
Submandibular gland
11316598
et al. reported the complete coding sequence of the human SCNN1G gene establishing that it has 13 exons The positions of introns are conserved in all three human ENaC genes, SCNN1A, SCNN1B and SCNN1G. The positions of the introns are also highly conserved across vertebrates See: Ensembl GeneTree. The three ENaC subunits encoded by SCNN1A, SCNN1B, and SCNN1G are commonly expressed in tight epithelia that have low water permeability. The major organs where ENaC is expressed include parts of the kidney tubular epithelia, the respiratory airway, the female reproductive tract, colon, salivary and sweat glands. ENaC is also expressed in
SCNN1G
8058278
day in order to obtain adequate nutrition. Therefore, the digestive system of a horse is about long, and most of this is intestines. Digestion begins in the mouth, which is also called the "oral cavity." It is made up of the teeth, the hard palate, the soft palate, the tongue and related muscles, the cheeks and the lips. Horses also have three pairs of salivary glands, the parotoid (largest salivary gland and located near the poll), mandibular (located in the jaw), and sublingual (located under the tongue). Horses select pieces of forage and pick up finer foods, such as grain,
Equine anatomy
13993442
form of treatment, radiation therapy is not without its side effects. Radiation therapy kills cancer cells by damaging their DNA (the molecules inside cells that carry genetic information and pass it from one generation to the next) (1).Radiation therapy can either damage DNA directly or create charged particles (free radicals) within the cells that can in turn damage the DNA. (2) Radiation therapy can lead to dry mouth from exposure of salivary glands to radiation. The salivary glands lubricate the mouth with moisture or spit. Post therapy, the salivary glands will resume functioning but rarely in the same fashion. Dry
Treatment of cancer
13729396
the crop and proventriculus, and then on ward to the midgut, as in most insects. Alternately, the foregut may expand into a very enlarged crop and proventriculus, or the crop could just be a diverticulum, or fluid filled structure, as in some Diptera species. The salivary glands (element 30 in numbered diagram) in an insect's mouth produce saliva. The salivary ducts lead from the glands to the reservoirs and then forward through the head to an opening called the salivarium, located behind the hypopharynx. By moving its mouthparts (element 32 in numbered diagram) the insect can mix its food with
Insect morphology
19062312
and another that does not. A new flagellum will later grow on the part that lacked a flagellum. Further longitudinal division distributes the nuclei between the forming daughter cells. Reproduction and multiplication of Phytomonas generally stops after entering the insect host. Within the first week inside the host, the parasites elongate to form "giant" versions of themselves inside the pylorus of the host. After 12 days, cells migrate to the salivary glands via the haemolymph. It is here, in the salivary glands, where multiplication resumes again, producing regular sized forms for infection of plant hosts. Depending on species and isolate,
Phytomonas
9453459
Labial glands The labial glands are minor salivary glands situated between the mucous membrane and the orbicularis oris around the orifice of the mouth. They are circular in form, and about the size of small peas; their ducts open by minute orifices upon the mucous membrane. Like the parotid and buccal glands, the labial glands are innervated by parasympathetic fibres that arise in the inferior salivatory nucleus, travel with the glossopharyngeal nerve and lesser petrosal nerve to the otic ganglion, where they synapse and then continue to the labial glands. Sympathetic innervation is mediated by postganglionary fibres which arise in
Labial glands
2702393
to other parts of the body. These tumors are almost never life-threatening. There are many types of benign salivary gland tumors, with names such as adenomas, oncocytomas, Warthin tumors, and benign mixed tumors (also known as pleomorphic adenomas). Benign tumors are almost always cured by surgery. Very rarely, they may become cancer if left untreated for a long time or if they are not completely removed and grow back. It’s not clear exactly how benign tumors become cancers. There are many types of salivary gland cancers. Normal salivary glands are made up of several different types of cells, and tumors
Adenoma
9838138
can either be broken down by monoamine oxidase or repackaged into vesicles by VMAT, making it available for future release. Norepinephrine is the main neurotransmitter used by the sympathetic nervous system, which consists of about two dozen sympathetic chain ganglia located next to the spinal cord, plus a set of prevertebral ganglia located in the chest and abdomen. These sympathetic ganglia are connected to numerous organs, including the eyes, salivary glands, heart, lungs, liver, gallbladder, stomach, intestines, kidneys, urinary bladder, reproductive organs, muscles, skin, and adrenal glands. Sympathetic activation of the adrenal glands causes the part called the adrenal medulla
Norepinephrine
11810099
rare for an adult to contract mumps. The incubation period for mumps can range from a couple weeks to a month, while the illness period is a few weeks. The swelling of the salivary glands is caused when the virus travels from the respiratory tract to the salivary glands and multiplies within the glands, causing the glands to swell. Viral replication is cytoplasmic. Entry into the host cells is achieved after viral attachment to host cells. Replication follows the negative stranded RNA virus replication model. Negative-stranded RNA virus transcription, using polymerase stuttering, through co-transcriptional RNA editing is the method of
Rubulavirus
1648759
by brushing them away. Therefore, licking would be a way of wiping off pathogens, useful if clean water is not available to the animal or person. In Pavlov's experiment, dogs were conditioned to salivate in response to a ringing bell, this stimulus is associated with a meal or hunger. Salivary secretion is also associated with nausea. Saliva is usually formed in the mouth through an act called gleeking, which can be voluntary or involuntary. A number of commercially available saliva substitutes exist. Saliva Saliva is a fluid substance formed in the mouths of animals, secreted by the salivary glands. Human
Saliva
17646676
the protozoan was discovered in a crab-eating monkey found in the same area Selangor and again in a separate crab-eating monkey in the Philippines. The newly discovered species was then named in honor of Dr. G. Robert Coatney, an American malariologist. The life cycle of "P. coatneyi" takes the complex form representative of the "Plasmodium" genus. When a female "Anopheles" mosquito bites a human, a haploid form of the protozoan called a sporozoite is transferred from the salivary glands into the circulatory system of the human. These motile sporozoites are then taken by the circulatory system to the liver, where
Plasmodium coatneyi
19825653
females of good condition, while by the end of the breeding season, males are less picky towards female condition, and breed more indiscriminately. Investment in reproduction is costly for male "P. cognata", as they must “woo” females, and eventually produce a salivary mass to initiate copulation. Once copulation has begun, sperm transfer itself is costly, as well. Sperm is transferred into the female via a sperm pump, which has two thick muscles, one on either side of the pump. Nutrient availability during the larval stage affects adult body weight, and the development of the males' salivary glands. Males with restricted
Panorpa cognata
17325570
open body cavities or "sinuses" collectively referred to as a hemocoel. Like most molluscs, "B. secunda" has a circumesophageal "nerve ring" or "nerve collar" composed of its pleural and pedal ganglia and their commissures and connectives within the region of the head. The esophagus passes through this nerve ring on its way back to the stomach; the esophageal pouches and salivary glands are located entirely before it. The cerebral ganglia are also located forward of the ring. Behind the nerve ring, the commissure of the pleural ganglia performs a characteristic "twist" common to many gastropods, the evolutionary result of torsion
Bathyacmaea secunda