Visualization 

 Challenges and selection 

 I am a formulation scientist working in pharmaceutical company . My job is to develop and   formulate a various Oral dosage forms ( Tablets , Capsules ) and scaling it up to commercial   scale . I started as a fresher with good background of pharmacokinetics mingled with   formulation technology understanding . Recently one project given to me along with my senior   colleague to formulate a generic product for a reference product or innovator product . The   innovator product cost is around 23 lakhs per 120 tablets . Our goal or objective is to produce   the bioequivalent product similar to Innovator or Reference product and reduce the cost of   tablet as minimum as possible so that it can be reached to maximum number of people at lower   cost ( affordability ) . Before joining the organization my collogue is already working on the   same project for last one year and failed to meet the bioequivalence ( BE ) criteria due to its high   variable nature . I read in detail regarding the project and understood reasons behind the failure   of BE studies with my pharmacokinetic background . So I faced so many issues in explaining   the factors responsible for BE failure and unable to explain in clear and understandable manner   to my colleague and peer members . Finally , visualization tool learned from this course helped   me a lot . This tool helped me a lot in providing the exact insights and ideas which I have   through diagrammatic representation , flow charts , different invitro tools to identify the root   cause in failure of BE and suggested some more invitro tools to match the BE criteria . 

 Application 

 During project review meeting with senior colleagues , explained some of my insights to meet   the BE criteria and made them understand all experiments need to perform , development of    the new invitro tools to make the product bring to market at lower cost with matching BE   criteria . I wrote all the reformulation experiments . But on the next day colleagues are in a   sceptical mode to perform the reformulation experiments and also upon development of new   invitro tools to identify the root cause . 

 Then I thought that there is some communication gap between me and my senior colleagues   because the colleagues all are skilled up but unable to receive the information mentioned orally   to them . This process continued for two weeks and unable to get the positive outcome . 

 Well , after attending the course I thought of applying the visualization tool . I started   considering fellow senior scientists as my first customer than the final patients who are in need   of product , so that if they understand properly , then a better version of the formulation could   be designed , and the BE criteria will be met and finally it will be commercialized and released   into the market at a cheaper and affordable price . 

 So , next day I asked the free time of senior scientist and made various flow charts making him   understand different approaches of formulation design combining different ingredients or   excipients . Made one by one invitro tool to identify the exact root cause of previous failure of   BE Study . Below is the some of the images of the visualization that I used to make them to   understand : 

 While making him understand even I got various ideas from my colleague to even sharpen up   the ideas to formulate and manufacture the Bioequivalent product . So , for me visualization tool   has many benefits . First , it makes people understand better what you want to convey and gives   you various new ideas to deal with the problem . 

 Insights and Approach 

 Well , what an output it was when we saw the results of invitro ( better invitro results in   comparison to failed BE formulation ) . It reflected exactly what I wanted and moreover had   elements that gave a wow factor in reducing the cost of BE product . The senior colleagues   could also add their experiences as they also understood what the concept is about as I made   them visualize the concepts of reformulation . Now , my company has a separate process in   between stages of formulation development to identify the best strategy to identify the product   which matches with the innovator in terms of safety and efficacy . We have discussions on the   BE Studies and created some platform to identify the similar line of products to bring the   essential medicines to market at lower cost so that it can be reaches at every corner of world .   In future , I will likely use this visualization tools further to identify more complex generic   molecules to match clinical BE criteria by systematically identifying the invitro tools and   techniques . 


EMAIL: 
ID_NUM: 
NAME_STUDENT: 
PHONE_NUM: 
STREET_ADDRESS: 
URL_PERSONAL: 
USERNAME: 

### Task: You are a PII (Personal Identity Information) Detection. Given a essays written by students, you have to identify ONLY the following:
NAME_STUDENT - The full or partial name of a student that is not necessarily the author of the essay. This excludes instructors, authors, and other person names.
EMAIL - A student’s email address.
USERNAME - A student's username on any platform.
ID_NUM - A number or sequence of characters that could be used to identify a student, such as a student ID or a social security number.
PHONE_NUM - A phone number associated with a student.
URL_PERSONAL - A URL that might be used to identify a student.
STREET_ADDRESS - A full or partial street address that is associated with the student, such as their home address.
### Input: Visualization 

 Challenges and selection 

 I am a formulation scientist working in pharmaceutical company . My job is to develop and   formulate a various Oral dosage forms ( Tablets , Capsules ) and scaling it up to commercial   scale . I started as a fresher with good background of pharmacokinetics mingled with   formulation technology understanding . Recently one project given to me along with my senior   colleague to formulate a generic product for a reference product or innovator product . The   innovator product cost is around 23 lakhs per 120 tablets . Our goal or objective is to produce   the bioequivalent product similar to Innovator or Reference product and reduce the cost of   tablet as minimum as possible so that it can be reached to maximum number of people at lower   cost ( affordability ) . Before joining the organization my collogue is already working on the   same project for last one year and failed to meet the bioequivalence ( BE ) criteria due to its high   variable nature . I read in detail regarding the project and understood reasons behind the failure   of BE studies with my pharmacokinetic background . So I faced so many issues in explaining   the factors responsible for BE failure and unable to explain in clear and understandable manner   to my colleague and peer members . Finally , visualization tool learned from this course helped   me a lot . This tool helped me a lot in providing the exact insights and ideas which I have   through diagrammatic representation , flow charts , different invitro tools to identify the root   cause in failure of BE and suggested some more invitro tools to match the BE criteria . 

 Application 

 During project review meeting with senior colleagues , explained some of my insights to meet   the BE criteria and made them understand all experiments need to perform , development of    the new invitro tools to make the product bring to market at lower cost with matching BE   criteria . I wrote all the reformulation experiments . But on the next day colleagues are in a   sceptical mode to perform the reformulation experiments and also upon development of new   invitro tools to identify the root cause . 

 Then I thought that there is some communication gap between me and my senior colleagues   because the colleagues all are skilled up but unable to receive the information mentioned orally   to them . This process continued for two weeks and unable to get the positive outcome . 

 Well , after attending the course I thought of applying the visualization tool . I started   considering fellow senior scientists as my first customer than the final patients who are in need   of product , so that if they understand properly , then a better version of the formulation could   be designed , and the BE criteria will be met and finally it will be commercialized and released   into the market at a cheaper and affordable price . 

 So , next day I asked the free time of senior scientist and made various flow charts making him   understand different approaches of formulation design combining different ingredients or   excipients . Made one by one invitro tool to identify the exact root cause of previous failure of   BE Study . Below is the some of the images of the visualization that I used to make them to   understand : 

 While making him understand even I got various ideas from my colleague to even sharpen up   the ideas to formulate and manufacture the Bioequivalent product . So , for me visualization tool   has many benefits . First , it makes people understand better what you want to convey and gives   you various new ideas to deal with the problem . 

 Insights and Approach 

 Well , what an output it was when we saw the results of invitro ( better invitro results in   comparison to failed BE formulation ) . It reflected exactly what I wanted and moreover had   elements that gave a wow factor in reducing the cost of BE product . The senior colleagues   could also add their experiences as they also understood what the concept is about as I made   them visualize the concepts of reformulation . Now , my company has a separate process in   between stages of formulation development to identify the best strategy to identify the product   which matches with the innovator in terms of safety and efficacy . We have discussions on the   BE Studies and created some platform to identify the similar line of products to bring the   essential medicines to market at lower cost so that it can be reaches at every corner of world .   In future , I will likely use this visualization tools further to identify more complex generic   molecules to match clinical BE criteria by systematically identifying the invitro tools and   techniques .
### Output: 