Hi doctor, I am a 29 year old female. I am trying to conceive for almost a year. In this time, I have had three miscarriages at 4 weeks, 6 weeks and 5 weeks respectively. With my last pregnancy, I was also on Baby Aspirin 75 mg and Progesterone 400 mg. But, it did not make any difference. I have been recently diagnosed with Grave's disease. During the last pregnancy, I had overt hyperthyroidism. Thyroid antibodies were ATPO 115 (elevated), anti-Tg 33 (mildly elevated) and TRAb 5.8 (elevated). I had a thrombophilia panel done which was clear, with only being heterozygous for MTHFR A1298C which I was told is not an issue. I was advised to have an APS panel and ANA. Shall I take Prednisone 10-15 mg to help with immune issues? In the meantime, I discovered that I have an arcuate uterus from an older MRI. I have read online that an arcuate uterus can be a cause of recurrent miscarriages, as it is a variant of a subseptate uterus. I will attach a photo of that MRI. My question is, if the APS panel is clear and I continue to lose pregnancies two to three times despite having my thyroid under control, is it reasonable to look into the arcuate uterus issue? If so, shall I go for hysteroscopic metroplasty to repair it? Is it a safe procedure? Will it help with my fertility?
Hi. For further information consult an infertility specialist online -->