Hello doctor, This query is regarding a 21 year old male having no health complications in the past who suddenly fainted after a party. We took him to our GP for the check up. The GP found nothing wrong and advised rest. However, we went to the lab on our own and carried out CBC. WBC count was high in the first report - 11,300, lymphocytes 4,500, and RDW 16 which was indicated as high in the report. The peripheral smear showed:  RBC: Normocytic normochromic with mild anisocytosis. WBC: Absolute lymphocytic leucocytosis. Platelets: Adequate.  We then went for one more blood test in the following week. This time the WBC was 7100 and lymphocytes 5100. The morphology report says:  RBC: normocytic normochromic. WBC: within normal limits. Platelets: adequate on smear. Impression: normal peripheral smear. No hemoparasites seen.  The boy has lost some weight. A mild night sweat is there. Please guide us.
Hello. The diagnosis in your case is lymphocytosis. The underlying cause for the lymphocytosis should be searched for. For that, a detailed physical examination should be done and liver, spleen and lymph nodes should be palpated. Infectious mononucleosis, viral influenza, hepatitis, lymphoproliferative disorders, syphilis, etc., are some of the causes. If any specific clinical complaint is present than provide history regarding that for further discussion. You investigate further according to need like influenza antibody testing, SGPT and SGOT, HIV testing, etc. Your peripheral smear examination reports are normal and are not showing any specific abnormal cells. You have to repeat CBC (complete blood count) again after a week. If lymphocytosis persists for more than three to four weeks then flow cytometry investigation should be done to rule out monoclonal nature of lesion. For more information consult a hematologist online -->