Hello doctor, I have Crohn's disease. Two years back, I was fine. I had gone through extreme stress early that year and after that, I had a flare-up. I lost 9 kg in a month. Then, the doctors detected ulcers in my ileum I was diagnosed with Crohn's. I was out of work for 14 months. Assuming that it is a genetic or immune system-related disease, I have a couple of questions.  Does it initiate due to stress? Does Crohn's get worse due to stress because now I need to take Humira every alternate week? Does the ulcers/flare-up happen due to stress?  I am currently on Humira (Adalimumab), Azathioprine, and Omeprazole.
Hi. You have a very good treatment response to Adalimumab. You are on top-down therapy. Usually, flares are due to non-compliance with medications, secondary infections or malignant transformation. Usually, stress does not cause flare-ups.  You may be switched back to Pentasa granules (Mesalazine) and Azoran (Azathioprine) as your terminal ileum has normalized endoscopically. You need to comply with medications. For more information consult a medical gastroenterologist online -->