Hi Doctor, My sister s double marker test says Down syndrome risk(T-21) 1:149 & concluded as Increased Risk. high risk cut off ratio is 1:270 Trisomy 18 risk 1:15129 - Normal risk high risk cut off ratio is 1:100 Neural tube defect risk Ultasound report on 16 weeks 1 days Nuchal fold thicknes measure 3.2mm(WNL) Fetal cardiac activity andmovements are well seen Forming placenta noted on posterior wall No evidence of subchronic hemorrhage Cervical length is adequate and OS is closed. Could you please let us let us know your suggestion. Does this baby at high risk due to Down syndrome? what is our next course of action. Please guide us..
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. As the baby is at high risk there should be amniocentesis to check about chromosomal abnormality of cell shed from baby in amniotic fluid ..as there is normal nuchal fold thickness it is a good hopeful sign .but amniocentesis should be done. Hope I have answered your query. Let me know if I can assist you further.