Hello doctor, I have occasional needle pin in hands and numbness. Mild itchy rash on nose and both upper shoulders (still there and barely visible). I also have slight hand tremors, increased permanent floaters in both eyes. I have CMV IgG 55 (recent infection). All STD, HIV, hepatitis, EBV, and HSV 1 and 2 are negative. Could CMV cause all these in an immunocompetent person? Ophthalmologist said that my eyes are perfect after an examination. Neurologist did a nerve conductivity test and said all reports normal. Infection specialist did western blot for HIV 1 and 2 at 16 weeks after symptoms started and said it is negative. HIV combo antibody and antigen also negative. If it is CMV, what is the treatment?
Hi,  Welcome to icliniq.com.  Answer to your queries are:  CMV IgG positivity indicates past infection. The exposure to CMV (cytomegalovirus) might have been there some weeks to years earlier. CMV is common in general infection and up to 60% are IgG positive. Sero- positivity percentage increases with age. Treatment for CMV is not given based on CMV IgG positivity. I suggest you to get following to rule out active CMV infection: 1. pp65 antigen.  2. ELISA CMV IgM.  3. CMV quantitative test.  4. Repeat your CMV IgG titers at least after six weeks of the above tests.  I suggest you to do thyroid profile, serum vitamin B12, and D3 tests. You can send pictures of your rashes for further assessment.  I hope this helps.