Hi doctor, Is a CMIA Abbott fourth generation negative test 100 % reliable at 13 weeks? Can both p24 and antibody remain undetected by a combo test? Does CMV coinfection increase window period?
Hi. HIV infection has a window period of 1 to 3 months during which the test results can be a false negative. According to WHO, all results are considered conclusive at 12 weeks after the last exposure. Hence, your test is definitive if done at 13th week. As per the protocol, if infected, either the antigen or antibody would reach detectable levels by 12 weeks. CMV (cytomegalovirus) infection does not alter the window period. Kindly upload the latest report to confirm the same.