Hello doctor,My friend's brother is diagnosed with blood cancer and has gone through first chemotherapy three weeks ago. According to acute leukemia immunophenotyping by flow cytometry report, morphologic and immunophenotypic findings are consistent with acute myeloid leukemia. Immunophenotypic findings include 73.6 % of viable cells are myeloblasts. The blast range from small to intermediate in size by a forward light scatter and express moderate CD 117, dim CD113, dim to negative CD33, bright CD34, heterogeneous CD38, heterogeneous HLA-DR but negative for CD10, CD20, CD3, CD45, CD56, Cd64. Advise given include cryogenetic studies including t(8,21), FLT3-ITD, NPMI, and CEBP-alpha mutation studies. The doctor is suggesting to do a bone marrow transplant for survival.
Hi. Sorry to hear about his ill health. Let me tell you that after seven days of the first round of chemotherapy, bone marrow biopsy should be done to check for the percentage of the blast. Ideally, it should be less than 5 % blast after the first round of chemotherapy. Then consolidation chemotherapy is given to prevent relapse of leukemia cells. Stem cell transplantation can be done in young age group people but it is costly. So various chemotherapy and stem cell transplant is the only therapy available. The mentioned cytogenetic and mutation study will help in predicting prognosis. You can follow hematooncologist advise for your condition.  AML. Cytogenetic study. Chemotherapy. Complete chemotherapy.