Hello doctor,My son was diagnosed with mediastinal neuroblastoma before nine months. He had undergone surgery and tumor was removed completely he had undergone chemotherapy for six cycles before three months. And the myc test was negative and favorable histology and pathology report. I want to know what the chances of recurrence and how to take care of that are? Is there a chance that it recurs in some other place also?
Hello. Can you answer a few questions? 1. What was the baseline stage? Whether bone marrow, lymph nodes, or bones were involved? Baseline imaging? 2. What was the histopathology report after surgery? 3. What was a response after chemotherapy? 4. Any cytogenetic studies? Neuroblastoma especially if the not high risk is highly curable. As per information available, he will be under the intermediate-risk group. Average five-year survival chance is 90 % in these cases. Usually, we keep patients on the follow-up to see for recurrence. There are no specific treatments to prevent recurrence in a low or intermediate-risk group as recurrences are rare. Transplant and new antibodies like anti GD2 are used in high-risk groups to prevent a recurrence. If you can provide me with the above details, I will be in a better position to answer your question.