Hello doctor, Two weeks ago, I started Wellbutrin SR. I started with a dose of 100 mg in the first week. In the second week, I went up to 200 mg following doctor's orders. The doctor also prescribed Trazodone 100 mg at night when needed for sleep. I stopped taking Trazodone because I felt drained and exhausted all day. The next day, I was also taking Wellbutrin in the morning. Once I stopped the Trazodone, I immediately felt a difference. I was not exhausted and I was not irritable. It has been five days since I started experiencing a bad taste in my mouth and overall I am not feeling good. I have also been taking Phentermine 37.5 mg for weight loss for the past two weeks. I am also on a birth control pill. Could this be the cause of it? I have a bad taste in my mouth, constipation, headaches, and a stomachache. In the past, I have taken Lexapro for depression. I have gained weight of 20 pounds in three months, have lost the sexual drive, and I have exhaustion and I am irritable. What can be done?
Hello. Your unpleasant taste in the mouth could be due to one of the two reasons listed below:  Are you a smoker? Which type of OCPs are you taking? Do you have any family history of blood clots? Did you have any blood clots in the legs or lungs? I suggest you try Omeprazole 20 mg once daily 30 minutes before breakfast daily. Consult your specialist doctor, discuss with him or her and with their consent take the medicines. Preventive measures include the fact that the combo of Phentermine and Wellbutrin together can increase the risk for seizures. If you are prone to seizures, have only one of these drugs. You need to reduce spicy and sweet foods intake. You should also avoid eating in the last two hours before bedtime. Follow up as needed. For more information consult an internal medicine physician online -->