Hi doctor, My brother is 37 years old. He is suffering from schizophrenia or schizoaffective (confused) disorder for the last three and a half years. The symptoms are an auditory hallucination, delusion, aggression, speaking to himself, grandiosity, and racing thoughts. Initially, for one and a half years, he was on Risperidone 3 mg and after six months of taking medicine, he got his insight. But, he was feeling some problem with Risperidone. So, after one year the doctor had changed the medicine to Quetiapine 400 mg. Just in two months, all the symptoms were gone (no auditory hallucination, no delusion, etc. He became alright. So the doctor decreased the Quetiapine dose to 300 then to 200. When we found him alright for three to four months, we have stopped the medicine, and the symptoms came again (first relapse). So the doctor increased the drug dose again to 300 mg. After one month, the symptoms were gone. But, we were giving the drug regularly without any miss. For the last one month, along with the previously mentioned symptoms, he has racing thoughts, aggression, sometimes weeping, sometimes laughing, and suicidal thoughts. The doctor had increased the dosage from 300 to 400 and now to 600 since one week, along with Clonazepam 75 mg. Still, his symptoms are not getting reduced. Please suggest us a good medicine. How can we handle the patient? He has a history of BP, fatty liver and gallbladder stone since one month. He is taking Amlopres AT and Udiliv 300.
Hi. I read your query with keen interest and understood your concern about the poor response of your brother to the current antipsychotics. I hope this answers you. Feel free to write back to me if you have more questions. I will be glad to assist you further. Thanks and regards. For further queries consult an andrologist online -->