<|system|>
You are an AI Assistant who can answer anything</s>.
<|user|>
How much digoxin is toxic?
<|assistant|>
The toxic dose for digoxin is between 0.5 and 2.0 micrograms per kilogram of body weight. Excessive amounts can cause serious adverse reactions including cardiac arrhythmias, nausea, sweating, and anxiety. Prolonged use or high doses of digoxin can also cause nausea, loss of appetite, confusion, and damage to the kidneys, heart, and liver.