Clint Capela (10) | Chris Paul (5) | Vivint Smart Home Arena18,306 | 11–13 |- style="background:#fcc;" | 25 | December 8 | @ Dallas | | James Harden (35) | Clint Capela (13) | Harden, Paul (8) | American Airlines Center20,254 | 11–14 |- style="background:#cfc;" | 26 | December 11 | Portland | | James Harden (30) | Chris Paul (11) | Chris Paul (10) | Toyota Center18,055 | 12–14 |- style="background:#cfc;" | 27 | December 13 | LA Lakers | | James Harden (50) | Clint Capela (13) | James Harden (11) | Toyota Center18,055 | 13–14 |- style="background:#cfc;" | 28 | December 15 | @ Memphis | | James Harden (32) | James Harden (12) | Harden, Paul (10) | FedExForum16,777 | 14–14 |- style="background:#cfc;" | 29 | December 17 | Utah | | James Harden (47) | Clint Capela (14) | Chris Paul (9) | Toyota Center18,055 | 15–14 |- style="background:#cfc;" | 30 | December 19 | Washington | | James Harden (36) | Clint Capela (12) | James Harden (9) | Toyota Center18,055 | 16–14 |- style="background:#fcc;" | 31 | December 20 | @ Miami | | James Harden (35) | Clint Capela (14) | James Harden (12) | American Airlines Arena19,600 | 16–15 |- style="background:#cfc;" | 32 | December 22 | San Antonio | | James Harden (38) | Clint Capela (22) | James Harden (10) | Toyota Center 18,055 | 17–15 |- style="background:#cfc;" | 33 | December 25 | Oklahoma City | | James Harden (41) | Clint Capela (23) | James Harden (7) | Toyota Center 18,055 | 18–15 |- style="background:#cfc;" | 34 | December 27 | Boston | | James Harden (45) | Clint Capela (18) | James Harden (6) | Toyota Center 18,055 | 19–15 |- style="background:#cfc;" | 35 | December 29 | @ New Orleans | | James Harden (41) | James Harden (9) | Austin Rivers (7) | Smoothie King Center17,555 | 20–15 |- style="background:#cfc;" | 36 | December 31 | Memphis | | James Harden (43) | Clint Capela (13) | James Harden (13) | Toyota Center18,055 | 21–15 |- style="background:#cfc;" | 37 | January 3 | @ Golden State | | James Harden (44) | Clint Capela (21) | James Harden (15) | Oracle Arena19,596 | 22–15 |- style="background:#fcc;" | 38 | January 5 | @ Portland | | James Harden (38) | Clint Capela (21) | James Harden (8) | Moda Center19,577 | 22–16 |- style="background:#cfc;" | 39 | January 7 | Denver | | James Harden (32) | Clint Capela (9) | James Harden (14) | Toyota Center18,055 | 23–16 |- style="background:#fcc;" | 40 | January 9 | Milwaukee | | James Harden (42) | Clint Capela (13) | P. J. Tucker (7) | Toyota Center18,055 | 23–17 |- style="background:#cfc;" | 41 | January 11 | Cleveland | | James Harden (43) | James Harden (10) | James Harden (11) | Toyota Center18,055 | 24–17 |- style="background:#fcc;" | 42 | January 13 | @ Orlando | | James Harden (38) | Clint Capela (10) | James Harden (12) | Amway Center16,982 | 24–18 |- style="background:#cfc;" | 43 | January 14 | Memphis | | James Harden (57) | James Harden (9) | Austin Rivers (6) | Toyota Center18,055 | 25–18 |- style="background:#fcc;" | 44 | January 16 | Brooklyn | | James Harden (58) | Harden, Tucker (10) | Harden, Rivers (6) | Toyota Center18,055 | 25–19 |- style="background:#cfc;" | 45 | January 19 | LA Lakers | | James Harden (48) | P. J. Tucker (9) | James Harden (6) | Toyota Center18,055 |