 The most recognized marker of acute Chagas disease is called <unk> 's sign , which includes swelling of the eyelids on the side of the face near the bite wound or where the bug feces were deposited or accidentally rubbed into the eye . Rarely , young children , or adults may die from the acute disease due to severe inflammation / infection of the heart muscle ( <unk> ) or brain ( <unk> ) . The acute phase also can be severe in people with weakened immune systems . 
