 Besides the nucleolus , the nucleus contains a number of other non @-@ membrane @-@ delineated bodies . These include Cajal bodies , Gemini of coiled bodies , <unk> interphase <unk> association ( <unk> ) , promyelocytic leukaemia ( PML ) bodies , paraspeckles , and splicing speckles . Although little is known about a number of these domains , they are significant in that they show that the nucleoplasm is not a uniform mixture , but rather contains organized functional <unk> . 
