 Nuclear import depends on the importin binding its cargo in the cytoplasm and carrying it through the nuclear pore into the nucleus . Inside the nucleus , RanGTP acts to separate the cargo from the importin , allowing the importin to exit the nucleus and be reused . Nuclear export is similar , as the <unk> binds the cargo inside the nucleus in a process facilitated by RanGTP , exits through the nuclear pore , and separates from its cargo in the cytoplasm . 
