 Mushroom <unk> from a number of species have attracted research interest for their <unk> and <unk> properties . <unk> from A. hygrometricus containing the <unk> named AE2 were found to inhibit the growth of several tumor cell lines in laboratory tests , and stimulated the growth of <unk> , <unk> , and bone marrow cells from mice . The extract also stimulated mouse cells associated with the immune system ; specifically , it enhanced the activity of mouse natural killer cells , stimulated macrophages to produce nitric oxide , and enhanced production of <unk> . The activation of macrophages by AE2 might be mediated by a <unk> @-@ activated protein kinase pathway of signal transduction . AE2 is made of the simple <unk> <unk> , glucose , and <unk> in a 1 : 2 : 1 ratio . 
