 Prevention mostly involves eliminating kissing bugs and avoiding their bites . Other <unk> efforts include screening blood used for transfusions . A vaccine has not been developed as of 2013 . Early infections are <unk> with the medication benznidazole or nifurtimox . <unk> nearly always results in a cure if given early , but becomes less effective the longer a person has had Chagas disease . When used in chronic disease , medication may delay or prevent the development of end – stage symptoms . <unk> and nifurtimox cause temporary side effects in up to 40 % of people including skin disorders , brain toxicity , and digestive system irritation . 
