 Discovered by Fox et al. in 2002 , paraspeckles are irregularly shaped compartments in the nucleus ' interchromatin space . First documented in <unk> cells , where there are generally 10 – 30 per nucleus , paraspeckles are now known to also exist in all human primary cells , transformed cell lines , and tissue sections . Their name is derived from their distribution in the nucleus ; the " para " is short for parallel and the " speckles " refers to the splicing speckles to which they are always in close proximity . 
