 Languedoc @-@ Roussillon wine , including the <unk> de pays labeled Vin de Pays d 'Oc , is produced in southern France . While " Languedoc " can refer to a specific historic region of France and Northern <unk> , usage since the 20th century ( especially in the context of wine ) has primarily referred to the northern part of the Languedoc @-@ Roussillon <unk> of France , an area which spans the Mediterranean coastline from the French border with Spain to the region of Provence . The area has around 700 @,@ 000 acres ( 2 @,@ 800 km2 ) under vines and is the single biggest wine @-@ producing region in the world , being responsible for more than a third of France 's total wine production . In 2001 , the region produced more wine than the United States . 
