 The <unk> epidemic in the 19th century severely affected the Languedoc wine industry , killing off many of the higher quality <unk> <unk> that were susceptible to the <unk> . American <unk> that was naturally resistant to <unk> did not take well to the limestone soil on the hillside . In place of these vines , acres of the lower quality <unk> , Alicante <unk> and Carignan were planted . 
