 The section of NY 78 between NY 5 in the town of Amherst and the Lake Ontario shoreline in Newfane was originally designated New York State Route 32 in the mid @-@ 1920s . In the 1930 renumbering of state highways in New York , NY 32 was absorbed into NY 78 , which ran from Gainesville to Newfane upon assignment . From East Aurora to Depew , NY 78 originally used a slightly more easterly alignment along several local streets and a section of NY 422 . Two realignments in the 1930s moved the route onto its modern alignment , and NY 78 's original routing between East Aurora and Depew was briefly designated NY 78A during the mid @-@ 1930s . 
