 The protagonist of Dead Head Fred is Fred Neuman ( voiced by John C. McGinley ) , a private detective . Fred is the only playable character , but since each head gives him a different set of animations , he could be considered nine separate characters . As he does not have a proper face , Fred 's mood is portrayed by the tone of his voice and by face @-@ like expressions formed by his eyes and frontal lobes . Fred has a wisecracking , sarcastic personality and occasionally breaks the fourth wall , such as heckling the player when he dies . Ulysses Pitt ( Jon Polito ) , the game 's primary antagonist , is a small @-@ time hoodlum turned racketeer . Pitt employs many henchmen throughout Hope Falls , the most prominent of which is his lieutenant Lefty , whose right leg has been amputated and replaced with a tommygun . Fred makes several allies throughout the game , including Dr. Steiner , who resurrected him , his girlfriend Jeanne Rossini ( Kari Wahlgren ) , and his former partner Benny Salazar . Fred 's enemies are generally employees of Pitt , like the skeletal " bone thugs " , or creatures created by Hope Falls ' radiation , like zombies and animated scarecrows . 
