 Like other Florentines of their financial means , Francesco 's family members were art lovers and patrons . His son Bartolomeo asked Antonio di <unk> <unk> to paint a fresco at the family 's burial site in the Basilica della Santissima Annunziata di Firenze . Andrea del Sarto painted a Madonna for another member of his family . Francesco gave commissions to Leonardo for a portrait of his wife and to Domenico <unk> for a painting of Saint Francis of Assisi . He is thought to have commissioned Lisa 's portrait to celebrate both Andrea 's birth and the purchase of the family 's home . 
