 Dr. Mario was designed by Gunpei Yokoi , creator of the Game Boy and Game & Watch handheld systems , and produced by Takahiro Harada , who also acted as producer of the Metroid series . The game 's music , later re @-@ used and arranged in games such as Super Smash Bros. Melee , was composed by Hirokazu Tanaka , who later became president of Creatures Inc . , an affiliate of Nintendo that owns one @-@ third of the copyright regarding the Pokémon franchise . 
