 In the treatment of diabetic foot infections , linezolid appears to be cheaper and more effective than vancomycin . In a 2004 open @-@ label study , it was as effective as ampicillin / <unk> and Amoxicillin / <unk> acid , and far superior in patients with foot ulcers and no osteomyelitis , but with significantly higher rates of adverse effects . A 2008 meta @-@ analysis of 18 randomized controlled trials , however , found that linezolid treatment failed as often as other antibiotics , regardless of whether patients had osteomyelitis . 
