 In 1520 the confraternity of the Blessed Sacrament ( Italian : <unk> del <unk> Sacramento ) was entrusted with the church 's care . The confraternity originated in Borgo in 1509 . On a windy evening of 1506 , a Carmelite coming from the old Santa Maria in Traspontina church ( lying near Castel Sant 'Angelo ) , followed by a lay brother bearing a candle , was bringing the sacramental bread to a sick person . Since the wind had extinguished the candle , the layman went into a nearby shop asking for fire , so that the priest was left alone . At the sight of the lone priest bearing the blessed Sacrament , several passers @-@ by were moved , gathered around him and accompanied him , bearing a baldachin and torches . The group grew , and on 3 September 1509 its members formed a <unk> . The Carmelites assigned it to a chapel in Santa Maria in Traspontina , and in 1513 Pope Leo X ( r . 1513 – 21 ) acknowledged the association , which in 1520 moved to San Giacomo . 
