 In adults and children over the age of 12 , linezolid is usually given every 12 hours , whether orally or intravenously . In younger children and infants , it is given every eight hours . No dosage adjustments are required in the elderly , in people with mild @-@ to @-@ moderate liver failure , or in those with impaired kidney function . In people requiring hemodialysis , care should be taken to give linezolid after a session , because dialysis removes 30 – 40 % of a dose from the body ; no dosage adjustments are needed in people undergoing continuous hemofiltration , although more frequent administration may be warranted in some cases . According to one study , linezolid may need to be given more frequently than normal in people with burns affecting more than 20 % of body area , due to increased <unk> clearance of the drug . 
