 In season 10 , Cristina decides to accept a job to run a state of the art clinic in Switzerland . Owen supports her decision as he realizes no good could come from him asking her to stay , but requests her not to leave him until she has to leave him for good , following which , they both spend two weeks leading to her permanent departure together . While saying her farewell to her colleagues of the last seven years , there is a possible act of terrorism in Seattle , which later turns out to be just a gas main explosion . Cristina has a quick but emotional goodbye hug with Derek , Bailey , and Webber , leaves her shares of the hospital to Alex , and dances it out with Meredith one last time to an old favorite song . Owen , however , is busy saving a patient in the O.R. , so they share a silent goodbye through the gallery 's glass . 
