 Linezolid was discovered in the 1990s by a team at Pharmacia and Upjohn Company and first approved for use in 2000 . It is on the World Health Organization 's List of Essential Medicines , the most important medications needed in a basic health system . Linezolid costs approximately US $ 100 per tablet in the United States . Nonetheless , it appears to be more cost @-@ effective than generic alternatives such as vancomycin , mostly because of the possibility of switching from intravenous to oral administration as soon as patients are stable enough , without the need for dose adjustments . 
