 A number of acquired conditions augment the risk of thrombosis . A prominent example is antiphospholipid syndrome , which is caused by antibodies against constituents of the cell membrane , particularly lupus anticoagulant ( first found in people with the disease systemic lupus erythematosus but often detected in people without the disease ) , anti @-@ cardiolipin antibodies , and anti @-@ β2 @-@ glycoprotein 1 antibodies ; it is therefore regarded as an autoimmune disease . In some cases antiphospholipid syndrome can cause arterial as well as venous thrombosis . It is also more strongly associated with miscarriage , and can cause a number of other symptoms ( such as <unk> reticularis of the skin and migraine ) . 
