 In October 2006 , RosettaDock was integrated into Rosetta @ home . The method used a fast , crude docking model phase using only the protein backbone . This was followed by a slow full @-@ atom refinement phase in which the orientation of the two interacting proteins relative to each other , and side @-@ chain interactions at the protein – protein interface , were simultaneously optimized to find the lowest energy conformation . The vastly increased computational power afforded by the Rosetta @ home network , in combination with revised " fold @-@ tree " representations for backbone flexibility and loop modeling , made RosettaDock sixth out of 63 prediction groups in the third CAPRI assessment . 
