 Morpholinos have been used to block miRNA activity and maturation . <unk> tagged Morpholinos , combined with fluorescein @-@ specific antibodies , can be used as probes for in @-@ situ hybridization to miRNAs . Morpholinos can block ribozyme activity . U2 and U12 snRNP functions have been inhibited by Morpholinos . Morpholinos targeted to " slippery " mRNA sequences within protein coding regions can induce translational <unk> . Morpholinos can block editing of RNA . Activities of Morpholinos against this variety of targets suggest that Morpholinos can be used as a general @-@ purpose tool for blocking interactions of proteins or nucleic acids with mRNA . 
