 Dr. Helen Bryce , portrayed by Emmanuelle Vaugier in nine episodes between seasons two and three , is a Smallville medical doctor who first appears in an anger management class Lex is sentenced to attend in the season two episode " <unk> " . She and Lex begin a romantic relationship which eventually turns into an engagement in season two 's " Precipice " . Her relationship with Lex concerns Jonathan when Helen — after taking a sample of blood from Clark during a period when he was infected by kryptonite — discovers Clark is not human in the episode " Fever " . Helen promises Jonathan she will keep Clark 's secret , but at the same time she does not destroy the vial of blood she took from Clark . As a result , the blood is stolen from her office in season two 's " Calling " , though it did not have Clark 's name on it . Lex confesses he stole the vial of blood , which causes Helen to break up with him . Helen returns in the season two finale , where she forgives Lex and goes through with the marriage . Helen then drugs Lex on the way to their honeymoon , and leaves him to die in his LuthorCorp jet . When Lex returns in the season three episode " Phoenix " , he orchestrates his own plan for revenge resulting in Helen 's own disappearance while the two go on their second honeymoon . 
