 New York State Route 376 ( NY 376 ) is a state highway located entirely within Dutchess County in the Hudson Valley region of New York in the United States . The route begins at an intersection with NY 52 in East Fishkill and passes north through Hopewell Junction and Red Oaks Mill on its way to the city of Poughkeepsie . It ends at a junction with U.S. Route 44 ( US 44 ) and NY 55 east of the city limits in Arlington , a hamlet in the town of Poughkeepsie . NY 376 was originally designated as part of NY 39 in the mid @-@ 1920s . In the 1930 renumbering of state highways in New York , the East Fishkill – Poughkeepsie portion of NY 39 was renumbered to New York State Route 202 . NY 202 was renumbered to NY 376 in 1934 to avoid numerical duplication with the new US 202 . 
