 Lisa and Francesco had five children : Piero , Camilla , Andrea , Giocondo , and Marietta , four of them between 1496 and 1507 . Lisa lost a baby daughter in 1499 . Lisa also raised Bartolomeo , the son of Francesco and his second wife , Camilla di Mariotto Rucellai , who was about a year old when his mother died . Lisa 's stepmother , Caterina di Mariotto Rucellai , and Francesco 's first wife were sisters , members of the prominent Rucellai family . 
