 In 2007 , at the 59th Primetime Emmy Awards , Heigl won the award for Outstanding Supporting Actress in a Drama Series , while Knight was nominated for Outstanding Supporting Actor in a Drama Series . Numerous guest actresses have been nominated for Outstanding Guest Actress in a Drama Series , including Burton in 2006 and 2007 , Christina Ricci in 2006 , Reaser in 2007 , Diahann Carroll in 2008 , and Sharon Lawrence in 2009 , but the only actress to have won the award is Devine in 2011 , who was nominated again in 2012 . The show has also been nominated for thirteen Creative Arts Emmy Awards , having won three of them : Outstanding Casting for a Drama Series , Outstanding Makeup for a Single @-@ Camera Series ( Non @-@ Prosthetic ) , and Outstanding Prosthetic Makeup for a Series , Miniseries , Movie or a Special . 
