 <unk> Elmore James revived the song with recordings in 1954 and 1960 – 1961 . English guitarist Eric Clapton with Cream popularized the song as " Crossroads " in the late 1960s . Their blues rock interpretation inspired many cover versions and the Rock and Roll Hall of Fame included it as one of the " 500 Songs That Shaped Rock and Roll " . Rolling Stone placed it at number three on the magazine 's list of the " Greatest Guitar Songs of All Time " in recognition of Clapton 's guitar work . 
