 RosettaDock was used to model docking between an antibody ( immunoglobulin G ) and a surface protein expressed by the cold sore virus , herpes simplex virus 1 ( HSV @-@ 1 ) which serves to degrade the antiviral antibody . The protein complex predicted by RosettaDock closely agreed with the particularly difficult @-@ to @-@ obtain experimental models , leading researchers to conclude that the docking method has potential in addressing some of the problems that X @-@ ray crystallography has with modeling protein – protein interfaces . 
