 Another component of Rosetta , RosettaDock , was used in conjunction with experimental methods to model interactions between three proteins — lethal factor ( LF ) , edema factor ( EF ) and protective antigen ( PA ) — that make up anthrax toxin . The computational model accurately predicted docking between LF and PA , helping to establish which domains of the respective proteins are involved in the LF – PA complex . This insight was eventually used in research resulting in improved anthrax vaccines . 
