 A large meta @-@ analysis of randomized controlled trials found linezolid to be more effective than glycopeptide antibiotics ( such as vancomycin and teicoplanin ) and beta @-@ lactam antibiotics in the treatment of skin and soft tissue infections ( SSTIs ) caused by Gram @-@ positive bacteria , and smaller studies appear to confirm its superiority over teicoplanin in the treatment of all serious Gram @-@ positive infections . 
