 The main goal of treatment is to treat shock and preserve kidney function . Initially this is done through the administration of generous amounts of intravenous fluids , usually isotonic saline ( 0 @.@ 9 % weight per volume sodium chloride solution ) . In victims of crush syndrome , it is recommended to administer intravenous fluids even before they are extracted from collapsed structures . This will ensure sufficient circulating volume to deal with the muscle cell swelling ( which typically commences when blood supply is restored ) , and to prevent the deposition of myoglobin in the kidneys . Amounts of 6 to 12 liters over 24 hours are recommended . The rate of fluid administration may be altered to achieve a high urine output ( 200 – 300 ml / h in adults ) , unless there are other reasons why this might lead to complications , such as a history of heart failure . 
