 The designations remained in place until 1924 , when actual route designations were assigned in the commonwealth . The part that was later made as part of U.S. Route 15 , which was then changed to an alignment of Route 287 , was designated as Route 4 ( over the Susquehanna Trail ) . The route received another designation in 1926 , upon the creation of United States Highways across the country . The portion from Tioga to an intersection with the current day U.S. Route 15 was designated as part of U.S. Route 220 . 
