 Keynote talks are presented in a single track and generally attract the largest audience . These presentations are chosen to highlight outstanding research in the field of bioinformatics . Notable ISMB keynote speakers have included eight Nobel laureates : Richard J. Roberts ( keynote speaker in 1994 , 2006 ) , John Sulston ( 1995 ) , Manfred Eigen ( 1999 ) , Gerald Edelman ( 2000 ) , Sydney Brenner ( 2003 ) , Kurt Wüthrich ( 2006 ) , Robert Huber ( 2006 ) and Michael Levitt ( 2015 ) . 
