 The Binding of Isaac 's main concept was the result of a weeklong game jam that McMillen had with Florian Himsl ; at the time , his co @-@ contributor on Super Meat Boy , Tommy Refenes , was on vacation . The concept McMillan had was two @-@ fold : to develop a roguelike title based on the first The Legend of Zelda game 's dungeon structure , and to develop a game that addressed McMillen 's thoughts on religion . McMillen had been inspired by Shigeru Miyamoto , the designer of the original Zelda games . 
