 A component of the Rosetta software suite , RosettaDesign , was used to accurately predict which regions of amyloidogenic proteins were most likely to make amyloid @-@ like fibrils . By taking hexapeptides ( six amino acid @-@ long fragments ) of a protein of interest and selecting the lowest energy match to a structure similar to that of a known fibril forming hexapeptide , RosettaDesign was able to identify peptides twice as likely to form fibrils as are random proteins . Rosetta @ home was used in the same study to predict structures for amyloid beta , a fibril @-@ forming protein that has been postulated to cause Alzheimer 's disease . Preliminary but as yet unpublished results have been produced on Rosetta @-@ designed proteins that may prevent fibrils from forming , although it is unknown whether it can prevent the disease . 
