 SR 22 begins at exit 50 on the concurrent I @-@ 82 / US 12 as a hybrid diamond – partial cloverleaf interchange The route heads south through farmland towards the town of Toppenish in Yakima County , which is also part of the Yakama Indian Reservation . While in Toppenish , the highway passes over double track belonging to BNSF Railway . On the south end of town , SR 22 intersects US 97 , turning southeast as US 97 heads south . Traveling southeast , SR 22 passes through more farmland , passing the small census @-@ designated place of Satus and an interchange with SR 223 . The city of Mabton is located just north of the highway , and is accessible by turning onto SR 241 . The highway leaves the reservation and turns southwest after passing the Sunnyside Wildlife Recreation Area , and crosses the Yakima – Benton county line , continuing through farmland until approaching the outskirts of Prosser , the county seat of Benton County . SR 22 serves as a bypass of Prosser , turning north until intersecting Wine Country Road and the Desert Wind Winery on the east side of Prosser before turning back southwest on Wine Country Road and terminating at a folded diamond interchange , exit 82 , on I – 82 . 
