 Like nearly all antibiotics , linezolid has been associated with Clostridium difficile @-@ associated diarrhea ( CDAD ) and pseudomembranous colitis , although the latter is uncommon , occurring in about one in two thousand patients in clinical trials . C. difficile appears to be susceptible to linezolid in vitro , and linezolid was even considered as a possible treatment for CDAD . 
