 Cisplatin , or cis @-@ diamminedichloroplatinum ( II ) is the first of a series of square planar platinum ( II ) -containing chemotherapy drugs , including carboplatin and oxaliplatin . These compounds are capable of crosslinking DNA , and kill cells by similar pathways to alkylating chemotherapeutic agents . ( Side effects of cisplatin include nausea and vomiting , hair loss , tinnitus , hearing loss , and nephrotoxicity . ) 
