 The University System of Ohio is the nation 's largest comprehensive public system of higher education . Member universities include the University of Cincinnati , which has a $ 3 + billion annual economic impact and is the largest employer in Cincinnati , Kent State University , which contributes a $ 1 @.@ 9 billion economic impact in Northeast Ohio , and the University of Toledo , which contributes a $ 1 @.@ 1 billion economic impact in Northwest Ohio . 
