 One of Oscorp 's leading scientific minds who attempts to engineer a revolutionary regeneration serum to help regrow limbs and human tissue . Something goes wrong , and he is transformed into the monster known as the Lizard . Ifans said his character spends the majority of the film as a human . While playing the 9 @-@ foot @-@ tall reptile , Ifans was required to wear a CGI suit . Initially , a large stunt @-@ double was used as a stand @-@ in for the role , but Ifans insisted on portraying the transformed character . Commenting on the technology used to bring his character to life , Ifans continued , " I had a green suit on , and then this cardboard head , and these small claws ... Each and every time you see the Lizard , the technology is so advanced now that when the Lizard 's eyes move , they 're my eyes . If I frown or show any emotion , they 're my emotions . That 's how spectacularly advanced technology is . " Ifans said that he voiced the man @-@ beast as well , explaining , " I 'm sure the voice will be toyed with in the eventual edits , but when I was shooting the CGI moments , when I wasn 't actually human , when I was Lizard , I looked like a crash @-@ test dummy in a green leotard thing . There were many moments when I had to speak to Andrew Garfield and Emma Stone as the Lizard . " 
