 Some frogs and toads inflate themselves to make themselves look large and fierce , and some spadefoot toads ( Pelobates spp ) scream and leap towards the attacker . Giant salamanders of the genus Andrias , as well as Ceratophrine and Pyxicephalus frogs possess sharp teeth and are capable of drawing blood with a defensive bite . The blackbelly salamander ( Desmognathus quadramaculatus ) can bite an attacking common garter snake ( Thamnophis sirtalis ) two or three times its size on the head and often manages to escape . 
