 In 1937 , Macmillan 's health was failing . In June , a leg was amputated , and her heart was weak . On 21 September she died of heart disease , at home in bed at 8 Chalmers Crescent , Edinburgh . On 23 September her body was cremated . In her will , she specified bequests to the Open Door International for the Economic Emancipation of the Woman Worker , and to the Association for Moral and Social Hygiene . 
