 By the end of 2006 , ISCB was in financial difficulty . Two conferences ( ISMB 2003 , in Brisbane and ISMB 2006 , in Fortaleza ) had drastically reduced numbers of participants due to their location , with a corresponding reduction in income . To allow more delegates to attend , it was decided to limit conference locations to North America and Europe . In January 2007 , ISMB and ECCB agreed to hold joint conferences in Europe every other year , beginning with ISMB / ECCB 2007 . ISMB would be held in North America in the years between joint meetings . As of 2016 , this pattern has been confirmed to continue until at least 2019 . ISMB / ECCB 2007 ( held in Vienna , Austria ) marked the first conference for which ISCB took full responsibility for organising . Vienna became the first city to host ISMB twice with ISMB / ECCB 2011 . This ' return visit ' was an experiment intended to reduce the increasing effort required to find suitable conference venues . Although the return to Vienna was only deemed partially successful due to price increases , Boston ( which hosted ISMB 2010 and 2014 ) is predicted to become a ' safe ' site which ISMB can periodically return to . 
