Yes, there's a neurological process that may overstimulate the vagus nerve, which causes pain, nausea, or chest tightness.
It is often said that the affects of heartache produces stress and other emotions.
Hey. My heart hurts from a broken relationship... That's too bad. A broken heart is a metaphor, but it can refer to physical pain or stress. That's interesting. What else do you know about broken hearts? It's a concept that's thought to be universal. Many cultures use the same words to describe it. Ah, OK. Is there anything physically happening when we feel a broken heart?
The neurological process involved in the perception of heartache is not known, but is thought to involve the anterior cingulate cortex of the brain, which during stress may overstimulate the vagus nerve causing pain, nausea or muscle tightness in the chest.