A 61 year old female friend has a swelling on her skull, between her skin and her skull for over one year. It started over her left ear and is not on her forehead. It came on suddenly and is extremely painful. She has been to Mayo Clinic twice and still no diagnosis and the only relief she gets is from taking pregnosone. They can tell her what is is NOT. She has had two big biopsies. It is not giant cell arteitis (sp?) It is not a cancerous tumor. They mentioned that it could be related to arthritis, which she has, but two types of arithitis medicine  do not eleviate the pain or the swelling. It just recently appeared on her right side of her skull above her ear also.
Hi, dairy have gone through your question. I can understand your concern. You may have some soft tissue tumor or skin adnexal tumor.  You should go for biopsy of that lump.  If you don't get exact diagnosis then you can go for Immunohistochemistry study.  It will give you exact diagnosis. Then you should take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using Chat Doctor. Wish you a very good health.