Hi I have been diagnosed with Pernious anemia through the finding of the intrinsic factor blocking Ab and have been taking B12 injections. I believe I have had the symptoms of Pernious many years but also have been told I have fibromyalgia and just had a lip biopsy for sjogrens. I am not seeing many if any benefits to the B12 injections and even wonder if they are causing worse problems. I have ringing and low tone noises in my ear have been told I have trigeminal neuralgia and recently have had trouble with my sight and told it may not be wise to have a cataract removed because of my auto immune disease.I have had all sorts of other symptoms...numbness in limbs and aching in joints constipation, pains running up the sides of my neck and a bit of a cough, tiredness but no depression of course dry eye and mouth etc. What is happening to me? I am a 64 yr old female, 130 lb and 5ft 2inches tall. No history of high blood pressure.
Pernicious anemia is a disease where large, immature, nucleated cells (megaloblasts, which are forerunners of red blood cells) circulate in the blood, and do not function as blood cells; it is a disease caused by impaired uptake of vitamin B-12 due to the lack of intrinsic factor (IF) in the gastric mucosa. You are already taking it B12 injections, but the effect will take some time to come I will suggest to stick on to treatment and take some B12 rich food supplements (Fish, pork liver, etc) also.