My co workers baby was admitted last night to Texas Childrens Hospital with high fever, extremely elevated white blood count and swollen liver and spleen, she was informed a little while ago they are admitting the baby to the oncology department.  I am wondering what all this could mean.  She said they are running more test but has no more information.  Do you know what this could be?
Hi and welcome to Chat Doctor. Thank you for your query. I am Chat Doctor, I understand your concerns and I will try to help you as much as I can. Enlarged spleen is called splenomegaly and there are various causes possibly leading to this. In first case these are infections such as mononucleosis Parasitic infections, such as toxoplasmosis or Bacterial infections. It means that any infection in your body may lead to spleen enlargement.  Second most common causes include autoimmune diseases such as thrombocytopenia. If this is ruled out by specific tests then some other causes may be considered and some are more or less serious such as Leukemia Lymphoma, or noninflammatory diseases such as acidosis, lupus, and rheumatoid arthritis. In every case, infectious causes are treated with antibiotics and other causes may require surgical removal of spleen. I hope I have answered you query. If you have any further questions you can contact us in every time. Kindly regards. Wish you a good health.