my 20  year old has been treated with ITP since fri., it is now tues... count was at 2000 . platelets were given along with high dose iv steroids. came up to 6000wasnt given anymore platelets till sunday and platelets went to 3000. gave 1 more day of steroidsand 1 more platelets, monday was given ivig infusion with oral steroid. next morning level still at 6000 so waiting to see next step.. what should we anticipate? spleen looked normal. bone marrow test before taking spleen?
Hi! Thanks for your queries on the treatment protocol of ITP in young adults... Well, usually the platelets transfused into your circulation are destroyed the same way as your own platelets therefore, steroid is a must! Best way is to transfuse HLA-compatible platelets and IV immunoglobulin, monoclonal, to reduce other hazards as well, but the facility is hardly available...! In most ITP cases the bone marrow comes back to normal within 6-12 months if bone marrow contains large number of inactive megakaryocytes! Cytotoxic agents and bone marrow transplantation could be required in certain resistant cases...