My daughter has diffuse b cell lymphoma stage 4b, treatment with r chop disease progressed, treatment with r GDP, treatment progressed to cns, treatment with high dose methotrexate has reduced cns cancer but systemic cancer is now growing again.  She is 29 years old and will be starting chap next week for 2 cycles and then ?final restaging to determine if strictly palliative care is the only option.  What end stage symptoms should we expect?
Thanks for your question on Chat Doctor. I can understand your daughters situation and problem. Diffuse B cell lymphoma is very rapidly progressive in almost all lymph nodes in the body. It causes lymph node enlargement and obstruction in the lymphatic channel. So end stage symptoms can be bilateral lower limb lymphedema, superior vent cavalry syn Chat Doctor.  Opportunistic infections are also common due to lower immunity. So tuberculosis, fungal infection etc. are common in end stage of disease. Hope I have solved your query. I will be happy to help you further. Wishing good health to your daughter. Thanks.