My wife said she felt something bite the back of her hand while lying in bed.  It immediately went numb and tingly.  Within minutes she felt nauseated.   Hours or so later her arm is better, but she still feels sick.  Spyder?  Should she see a doctor?  We live in central Minnesota.
Hello, Welcome to Chat Doctor, I can understand your concern for insect bite. After reading your query it appears that you have developed insect bite hypersensitivity. This basically caused by hypersensitivity to the insect bite which can cause acute aggravation of the problem and flare up of the lesions. As you are not getting relief from the steroids an antihistamine, so I suggest you to meet a dermatologist and get your skin examined to get proper best treatment. You can apply steroid creams of higher potency for the early resolution of the lesions. You can take oral anti histamine like loratadine or levocetrizine under medial advice. If you have pain and irritation then you can take a tablet paracetamol or diclofenac. Do not scratch or rub the skin as it can lead to further aggravation. Despite above measures if the problem is not getting better than it is better to consult a dermatologist. Thank you.