My father is having parkinson for the past 17 yrs. He is now 73. The following are the drugs he is taking Syndopa 110 = 6Am-10AM-2PM-6PM Syndoppa CR = 8AM-8PM Urimax F = night Waklert 50 = morning One aspirine tablet (myogrel 75) - noon Morning he is able to walk .. but by noon .. he could not walk and not able do anything with out any others help. At night things become worst .. his thigh muscles becomes stiff and very painful so that he could not sleep.. What could be the reason?
Hello, Thanks for the query, I understand your problem All these symptoms that you have listed are mostly related to Parkinson disease itself. This is the natural history of the disease. The fluctuation that you have mentioned could be related to OFF period after syn dopa that generally happens in patients with this disease. He would require further dose adjustment of his medications after careful clinical examination. Further, I will like you to tell that there is another option for treatment of Parkinson disease called as DEEP BRAIN STIMULATION. You need to consult a movement disorder specialist (Neurologist with advanced training in this disease) for the same. I am sorry that I do not know your location. If you are form India, the centers that will help you are 1. The Free Chiara tribunal center, Driven Chat Doctor.  SIMIANS Bangalore 3. AIMS Hyderabad etc. Best wishes