hi doctor, i have liver dysfunction after taking mext. now doctor stopped mext  but prescibed sazo, defza and hcqs.Can i take these drugs with such liver dysfunction?(sgpt 55, sopt 44, bilirubin1.1). is theer any alternatve of methotroxate which do not affect liver? very much worried abt my liver.. but cant stop medicine due to severe joint pain if i stop so..  e mail
Hi and welcome to Chat Doctor. Thank you for your query. There are no alternatives unfortunately. These are medicines with bad effect on liver, and you just need to do frequent liver LFT check ups and ultrasounds. Your doctor must determine cost-benefit of these cytotoxic medicines. Also, this isn't significant elevation of LFT and it dissent mean that liver function is compromised very much.  Wish you good health.