Hi, may I answer your health queries right now ?  Please type your query here...  My husband was diagnosed with polycythemia over 20 yrs ago.  He has had regular phlebotomies for 20 yrs.  He is now experiencing more fatigue, an increased incidence of kidney stones, and an unexpleained wieght loss.  Are these signs that his polycythenia is approaching a spent phase
Hello, Polycythemia can result in a high serum uric acid level which can cause one type of kidney stone, and if his uric acid level is high, a medication called allopurinol can bring it down. The other symptoms could be related to his disorder, but other causes like low thyroid, low cortisol levels, leukemia, and lymphoma are also possible, so he needs evaluating for those. Hope I have answered your query. Let me know if I can assist you further.