My father was diagnosed with lymphoma a year ago. Tumor celll expressed CD20 and CD 5 and are negative for CD 3 CD10 and CD23 and cyclin D1. he was treated with Rituximab and bendamustin with 6 cycles for 6 months. He had a relapse within 2 months. He was given 3 cycles of Bortizomib Lenalidomide to no effect. IS there any treatment for this kind of aggressive lymphoma or even if there is any clinical trials available, please let me know about it. He is 80 years old.
Hello, Hope your Dad is doing well.  I am a Nuclear Medicine Physician. In case of relapsed disease of Non-Hodgkin Lymphoma after second and third line chemo therapies, there is still an option of a radionuclide therapy (Bexar, or Devlin). Both modalities show up to 60% overall response and prolong the survival. The side effects are less compared to conventional chemo therapies. Contact your oncologist or me for further details. Hope this could be of help Regards and best wishes