Hello my husband has glioblastoma grade 4 two year ago we went to the following procedures,surgery of the tumor in the frontal lobe, radiation and temodar for 2months, then 5days cycle monthly also on temodar , six months later he had a progression of the tumor , we stopped temodar and started on avastin every two weeks, he did well until two months ago he had a recurrent again, so we gave him one cycle of avastin and camptozar combination, his motor function is getting worse, what should I expect now?
HI, I can understand how much hardship you are facing this time due to cancer of your husband. I had a patient few months ago with similar kind of complaints. He is a young adult of 35\u00a0years, had nuroblastoma in frontal region. In spite of surgical resection and chemotherapy we could not make him alive for more than 6 months. What I mean from this scenario is, nuroblastoma is an aggressive cancer type with high rate of recurrence even after vigorous treatments. Even with good treatment options the life span is less than two years. Then God for giving more years of life to your husband. More the recurrence, less the duration of survival. Regarding the motor dysfunction, frontal lobe is the main motor area of brain. Any persisting disturbance in that area definitely causes worsening of functioning. I suggest you to give enough nutrition and physiotherapy for him. I am really sorry to say that the prognosis of this type of cancer is worse. Anyhow, continue the chemotherapy for better results.