I am a 27 year old African American female and I live with sickle cell disease. I have a sickle cell crisis between 2 to 5 times a year. I have a three year old son and I had a lot of complications with him but I am ready to have another child. Will me having sickle cell disease and so many crisis can this hinder my chances of conceiving?
HI, Sickle cell crisis is not known to hinder conception, it may affect maternal health, which may not be ideal for child bearing.  Another thing is, sickle cell being a genetically transmitted condition-its likely to pass same sufferings that you have to your offspring-thus making its life miserable.  From this point of view, I would advise to adopt a child instead, if you must have second child.  Thanks.