If a paitent experiences an allergic reaction to IV Cleo and is treated with benadryl and Tylenol and the IV site cannot be changed; how long should further antibiotic treatment be held (given that the antibiotic is DCd and replaced with another)? Should we wait for the half-life of benadryl to pass so as to not cover symptoms of a second allergy (the patient was unaware of the original allergy). Are there any published resources regarding this?
Cellophane You for contacting Chat Doctor. Whenever there is allergic reaction to Chat Doctor.  Reaction usually gets limited within few hours. After 4-6 hrs antibiotic can be given BUT same antibiotic group is avoided. Patients are in that case given alternative(second class) antibiotic for treatment. I would suggest to wait for at least 6 hrs and then start further medication. Hope this answers your question. If you have additional questions or follow-up questions then please do not hesitate in writing to us. Wishing you good health.