How soon does coumadin get in your blood system? My daughter was diagnosed with a blood clot in her right thigh and was put on coumadin we are giving her 2 injections every 12 hours and she is taking a pill as well. This was last Friday March 28,2014 Her leg is still very swollen, in the mornings when she wakes up it s not as swollen but by the evening time it s bad. She has it elevated up and her toes and foot get very cold is that normal? she said today it feels very tight and she is tired.
Hi, Thanks for asking. Based on your query, my opinion is as follows.1. Coumadin gets into the blood system immediately and gets activated within two hours and is active for up to 12 hours.2. Swelling is due to thrombus formation blocking the blood vessel leading to increased HY Chat Doctor. 3. continue the elevation. Not to worry, it will reduce slowly. Hope it helps. Any further queries, happy to help again.