My husband is hepatitis B carrier for the past one year.  He had a progression in SGOT and SGPT levels after taking Sebivo for the past one year.  The DNA level also came down from 7 IU to 1 IU.  But now this month, he checked for LFT and found elevated levels of SGOT and SGPT and we are awaiting results for DNA levels this week.  Could you guide me please.
HiT hanks for your query. Based on your query my opinion is1. Raised GOT and SGPT is indicative of liver pathology, in your husbands case, hepatitis. 2. Now that he is on treatment, the enzyme levels should have settled to normal. 3. Liver function would be better assessed by looking at other parameters like serum albumin and alkaline phosphatase levels along with DNA results.4. In the prevailing scenario, raised enzymes indicate continuing liver damage/ inflammation. Hope this yellowish him good health