We just found out that our newly adopted son has sickle cell disease. His HbF is 10.8 % and his HbS is 86.5% and his HbA2 is 2.7%. We are still in Africa with him and we hope to fly back to the states in the next few weeks. How should we be treating him now? What do there numbers mean for him longterm? Can the 86.5% get lowered? If so, how?
Your son have sickle son disease. Permanent treatment of it is very difficult and costly. It required bone marrow transplant and its very tidy and difficult. So you required symptomatic treatment. Many sickle cell disease child Chat Doctor.  Best treatment is oxygenation at the time of crisis or and symptoms. Because in this disease the RBC becomes sickles shaped when deoxygenated, and sickle like RBC can't pass through capillary network easily, and it will create some crisis and other problems. So oxygen is the main treatment, moreover you need long term folic acid treatment. It is helpful.