My daughter has been ill since January, 2011. Neurologist, Stanford doctors, Infectious Disease specialists have been unable to diagnose. Could Lyme Disease cause elevated IgE - total mid 500 s as well as non-specific brain lesions? Lesions in r frontal and l parietal lobes. Lumbar puncture normal, Immunoblot non-reactive, most labs w/in norm limits. Many sx mimic lyme. Removed 2 ticks, not sure how long before onset of sx, I m guessing w/in 1 month. Thank-you, Jill Stanley
Hi, I did review your concernLymes disease can cause elevated IGE. But elevated IGE is seen in many conditions like parasites infections, certain fungal infections, allergic condition like asthma and atop and rarely in congenital immunodeficiency like Jobs syn Chat Doctor.  With lesions in brain, it could be a parasitic infection and my advice would be serum liters for antibodies to parasites like toxoplasma and cysticerosis and also for Lyme disease these are negative, then you can consult an immunologist and get her evaluated for immunodeficiency disorder. I hope this yellowish you all the best! Thank you for choosing Chat Doctor !