My blood test results state CBC    Giant Platelets are present.  What does this mean?  I am a 68 year old woman with diabetes, polymyalgia rheumatica, hypertrophic cardiomyopathy, last year had a heart attack (mild), stroke and migraine that lasted more than 72-hours, even with hospital ER treatment (cant remember exact name of diagnosis).  I am 5 ft. in. and weigh 180.  I also have Charcot Joint disease and am scheduled to have my left foot operated on to remove bone that has caused a sore on the sole of my foot - had osteomylitis last year, and had my right foot operated on.   Id appreciate any info you can give me.  Sharon
Hi, Thanks for asking. Based on your query, my opinion is as follows.1. Giant platelets do not have any significance with normal platelet count and bleeding time.2. Do not worry about giant platelets. Most commonly secondary to It B12 deficiency.3. Take It B12 supplements and keep checking your platelet count monthly once. If it is normal. Not to worry. You can go for surgery, no problem. Hope it helps. Any further queries, happy to help again.