Hello! I am awaiting test results for CADASIL, have been watching my nephew for several years as he complains of several of the same issues I ve had for years (headaches, leg pain, etc...). His father seems fine. Do you know what the odds would be of my nephew having CADASIL? It has been confirmed in my cousins.
Hello, If the father of your nephew is not diagnosed with CDA SIL, your nephew is very unlikely to have it (unless his mother is diagnosed with CADA SIL). This because CADA SIL is inherited in an autosomal dominant manner. This means that having a mutation in only one copy of the responsible gene in each cell is enough to cause CADA SIL. Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor.