My nephew aged 36yrs now badly suffering from misuse of drugs such as Lorazepam , Alprazolam , irritable attitude, . As advised by doctor he is not taking the TOPARIMATE tablet due to loss of appetite, in addition to Cyproheptadine, Lithium . Now he is on mood disorder .and taking 4 to 8 mg Lorazepam per day. What is your advice
Hello and welcome to Chat Doctor. Thanks for your query. Taking multiple benzodiazepines, especially in high doses such as 8\u00a0mg of lorazepam is definitely not good. It is likely that he has become dependent on benzodiazepines. I would advise you to discuss with his doctor regarding a gradual tapering of the necessary Chat Doctor.  Regarding his \"mood disorder\", it is difficult to say which medication would be appropriate for him without knowing a detailed history and doing a proper psychological assessment. So, please discuss is medication with the treating psychiatrist. If Topiramate is causing side effects like loss of appetite, you can report this to his doctor, so that necessary alterations can be made in his medication regimen. Wish you all the best.