Nature of Spaecimen
Hi, How are you? Thanks for the very detailed histo-path report of the needle biopsy. But unfortunately it is very difficult to interpret the biopsy report without a clinical context. Please do let me know the clinical condition of the patient, esp his / her age and any symptoms, if any, they might be suffering from. What was the indication for the biopsy? Just by looking at the biopsy report, I would guess it's from a child (due to the extramedullary erythropoietin). There appears to be changes due to bile duct blockage (homeostasis and pustular reaction) which seems to have been going on for a while (due to portal tract expansion and initiation of fibrosis). Although cirrhotic changes are not yet seen, I would say, whatever the condition of the patient now, he is on his way there. The three most common conditions causing cirrhosis in a child have been ruled out (hemochromatosis - increased iron, Wilson's - Increased copper and Alpha 1 anti-trypsin deficiency)Please do let me know some clinical details regarding the patient so that I can advise you better. Please do not hesitate to contact me for any further details required - rxsuresh@gmail.com