My mother has a chest infection and has grown klebsiella. It is sensitive to cephalosporins, quinolones, and amino glycosides. She is on cefpodoxime plus clavulanic acid. Herbsputum has changed from green tomyellow iver the past four days while on antibiotics.Is this cephalosporin appropriate to treat klebsiella? Would doxycycline be more appropriate give the fact that klebsiella devolpes resistance to cephalosporin relatively quickly. How quickly I am not sure. She has not measured her temperature, but says she feels clammy.Thank you
Dear Friend. Welcome to Chat Doctor. I am Chat Doctor. I understand your concern. See, the sensitivity depends on the culture. If the klebsiella is sensitive to cephalosporins then Cefuroxime would help good. There is no need of adding doxycycline to her. In fact, if her fever responds well to this antibiotic, let her complete course for at least 7 days. Some doctors also prefer to give treatment for 14 days. If her fever doesn't responds then adding a quinolone like Levofloxacin would be an appropriate decision. This is my personal opinion for you based on available details. If you have any further query please ask me. Stay HealthyChatDoctor, MD