Hi,My wife following Spine tuberculosis witChatDoctorplete destruction of Lumber 5 vertebrae and associtaed facetal conguity has been treated with anti-tb medicines but with days going on, her nerve pain is increasing during sitting or walking. She has been given pregablin and amitriptyline but no sign of improvement of leg pain. Any complete recovery of the nerve pain possible?
Hello, There are two contributory factors in causing neurological pain. One is the organic cause, and it is directly relate to the destruction of the L5 vertebra. There are chances that the nerve roots are getting impinged due to disc space narrowing and the destruction of the vertebra. First line is medication and physiotherapy. If there is no considerable improvement then surgery is the next option. Second is the Anti tuberculosis Chat Doctor.  It is well documented that ATT will cause peripheral neuropathy due to pyridoxine deficiency. Treat will highly dose of pyridoxine supplements.