I am taking 200 mg of Pristiq and 30 mg lexapro and 450 wellbutrin. i need to raise my lexapro up to 40mg because i have alot of anxiety and it helped so much when i took 40 mg before i started the pristiq but now that pristiq has been added i m afraid to up it because of seratonin syndrome . what is your opinion on this? is it safe to up it to 40mg?
Hello...... Thanks for your query. Simultaneous administration of three antidepressant that too at higher doses is not advisable. At the maximum only two antidepressants are recommended to be combined. It definitely carries the risk of serotenergic syn Chat Doctor. Self-medication is not advisable. Request your psychiatrist to minimize number of medication and optimize the dosage. Wish you speedy recovery. Regards