I have had chronic lymphocytic leukemia for 20 years with no symptom Recently, I have had swelling in the lower legs. I have had my kidneys and heart checked and no problems. Can CLL be causing this? My lymphocyte count has risen to 11 from about 6 over the past 4 months. I
It is unlikely CLL by itself would cause these symptoms. Anemia, caused by CLL can cause leg swelling. Low levels of albumin (protein made in the liver), low levels of thyroid hormone, blockade of lymph supply from the legs (can be due to infections like filariasis, obesity), leaky valves in leg veins, and leg clots are other common causes of leg swelling. I would suggest seeing a general physician to evaluate this further. Keep your legs elevated when you are at rest.