Is there a way to select only column labels using Pyhon Pandas library without any rows?
Just dodataframe.columns to get all column names
This might be a silly question to ask, however, it is for a specific task in a multi-step process to clean up some data. 
Basically, each column label is a location represented as a series of long numbers. Each column contains measurement values in each subsequent row for those locations. I do not need the measurements, only the locations (hence why I just need the column labels only). 
The reason I need this is because I need to replace some mixed up column labels in one CSV file with the correct column labels from another CSV file. 
I cannot do this in Excel since there are too many columns to read in (over 300,000 columns). I am essentially looking for a way to do a coded "Copy" and "Paste" from one file to another using Pandas if it can be done. 
I had a considered just dropping the columns I do not need, however, because the columns are labelled as numbers, I'd be filtering based on a multiple set of a conditions. I thought this method would be easier. 
Thank you for your help.