to_excel on desktop regardless of the user
This depends on your operating system.
You're saying you'd like to save the file on the desktop of the user who is running the script right? 
On linux (not sure if this is true of every distribution) you could pass in "~/desktop/my_file.xls" as the path where you're saving the file
Is there a way to use pandas to_excel function to write to the desktop, no matter which user is running the script? I've found answers for VBA but nothing for python or pandas.