Significant improvement in physical activity was observed by day 2 (p < 0.0001) (Table 8). The ‘breathe easily’ factor was found to significantly improve by day 1 (p = 0.0449) and had the strongest correlation with nasal congestion (‘plugged nose’ symptom) factor (r = 0.72; p < 0.0001) (Table 12). The other two QoL factors ‘walk, climb stairs, exercise’ and ‘accomplish daily activities’, improved significantly by day 2 (Table 8). At the last dose administered for all participants who completed the study, physical activity improved significantly by 70.7% to a mean (±SE) score of 3.8 (±0.46), which indicates an impact closer to a very mild (score = 3) severity level. After last dose, the percentage of improvement in ‘breathe easily’, ‘walk, climb stairs, exercise’, and ‘accomplish daily activities’ was >70% for all (Table 8). The median time to resolution was day 4 for ‘walk, climb stairs, exercise’, and ‘accomplish daily activities’ and day 5 for ‘breathe easily’ (Figure 4).