WURSS-21 total symptom domain score ranges from 0 to 70, in which higher scores indicate higher severity. At baseline, the mean (±SE) of the WURSS-21 symptom domain score of the mITT population observed was 38.3 (±1.12), which represents a mild (score = 30) to moderate (score = 50) severity level [Figure 3(b) and Supplemental Table 2]. Statistically significant decreases in the WURSS-21 total symptom domain were observed consistently from day 2 to day 7 (p < 0.0001) (Supplemental Table 2).