The WURSS-21 total QoL domain score ranges from 0 to 63, in which higher scores indicate higher severity. At baseline, the mean (±SE) of the WURSS-21 total QoL domain score of the mITT population observed was 37.5 (±1.15), which represents a mild (score = 27) to moderate (score = 45) severity level [Figure 3(c) and Supplemental Table 2]. Statistically significant decreases in the WURSS-21 total QoL domain score were observed consistently from day 1 (p = 0.0481) to day 7 (p < 0.0001) (Supplemental Table 2). By the last dose administered, the difference in WURSS-21 QoL domain score was −26.39 (95% CI: −29.75 to −23.03; p < 0.0001) compared with baseline, representing a 70.4% improvement from baseline in WURSS-21 total QoL domain score at the last dose of the treatment needed for all participants who completed the study (n = 100) [Figure 3(c) and Supplemental Table 2].