WURSS-21 total score ranges from 0 to 133, in which higher scores indicate higher severity. At baseline, the mean [±standard error (SE)] of the WURSS-21 total score of the mITT population (n = 102) was 75.8 (±2.00), which represents mild (score = 57) to moderate (score = 95) severity level. Statistically significant decreases in the WURSS-21 total score were observed consistently from day 2 to day 7 of treatment with the study product (p < 0.0001 for all). At the last dose administered for all participants that completed the study (n = 100), a statistically significant difference in WURSS-21 total score indicated a significant improvement in symptoms and QoL factors [−51.09 (95% CI: −56.82 to −45.36; p < 0.0001)] compared with baseline [Figure 3(a) and Supplemental Table 2], with a 67.6% improvement from baseline to the last dose (Supplemental Table 2).