In terms of physical activity, these results suggest that once participants were able to breathe easily, they were able to increase their daily activities and even perform mild exercise after 2 days of treatment. The ‘walk, climb stairs, exercise’ factor and ‘accomplish daily activities’ both had a severity level of mild-to-moderate at baseline. After treatment with xylometazoline hydrochloride 0.1%, a significant improvement was observed from day 2, correlating with the symptom of ‘feeling tired’ from the vitality category. Furthermore, the QoL factor ‘breathe easily’ showed significant improvement on day 1 and demonstrated the strongest positive correlation with nasal congestion (‘plugged nose’ symptom) (r = 0.72).