Over-time mean scores for the primary endpoint measures for the mITT population (N = 102). (a) Total score is the sum of questions 2 through 20, ranging from 0 to 133. (b) Total symptom domain score is a sum of questions 2 through 11 ranging from 0 to 70. (c) Total QoL domain score is a sum of questions 12–20 ranging from 0 to 63. (d) WURSS-21 plugged nose symptom score range from 0 to 7. Last dose refers to all participants’ last day if prior to day 7.