The common cold can be caused by a plethora of different viruses.1,5 Due to the involvement of different pathologic mechanisms and the fact that the disease is acute and self-limited, there is no cure and it is usually managed through symptomatic treatment.5,18 Despite being a generally mild disease, the symptom severity of the common cold manifests widely among individuals9,19 and can impact QoL in terms of productivity9,20 and sleep quality, 9 among other factors. In particular, nasal congestion contributes significantly to sleep disturbances, absences from work, and general activity impairment.21,22