Individual scores ranged from 0 (not at all) to 7 (severely). The ‘physical activity’ category scores were calculated by adding the individual QoL factors scores grouped in this category. The ‘physical activity’ category score ranged from 0 (not at all) to 21 (severely). Higher scores indicate more negative impact of QoL domains. % Improvement is calculated as −100 * (mean change from baseline)/(baseline mean). p-Value presented using Student’s paired t-test.