The QoL category of sensation incorporates the senses of ‘smell’ (Q4) and ‘taste’ (Q5) from the additional QoL questions (Table 10). The sum of the individual scores determined the range of severity for the sensation category of 0–14. The ‘smell’ factor had a baseline mean (±SE) score of 4.8 (±0.16), considered to be moderate in severity level. The ‘taste’ factor had a mean (±SE) score of 4.2 (±0.19), considered mild (score = 3) to moderate (score = 5) in severity level. After day 1 of xylometazoline hydrochloride 0.1% use, the ‘smell’ and ‘taste’ senses improved significantly (p < 0.0001) (Table 10). Significant improvements continued throughout the study, and, at the last dose of treatment, the category of sensation had an improvement of 81%; the sense of ‘smell’ and the sense of ‘taste’ improved by 82.2% and 79.7%, respectively. The median time to resolution was day 3 for the sense of ‘taste’ and day 4 for the sense of ‘smell’ (Figure 4). A positive correlation with the symptom of ‘plugged nose’ and the sense of ‘smell’ was also observed (r = 0.61; p < 0.0001) (Table 12).