text: # -*- coding: utf-8 -*-
  # emacs: -*- mode: python; py-indent-offset: 4; indent-tabs-mode: nil -*-
  # vi: set ft=python sts=4 ts=4 sw=4 et:
  from __future__ import (print_function, division, unicode_literals,
                          absolute_import)
  
  import os.path as op
  import numpy as np
  
  from ... import logging
  from ...utils.filemanip import split_filename
  from ..base import (CommandLineInputSpec, CommandLine, BaseInterface, traits,
                      File, TraitedSpec, isdefined)
  iflogger = logging.getLogger('interface')
  
  
  class DWI2SphericalHarmonicsImageInputSpec(CommandLineInputSpec):
      in_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-2,
          desc='Diffusion-weighted images')
      out_filename = File(
          genfile=True, argstr='%s', position=-1, desc='Output filename')
      encoding_file = File(
          exists=True,
          argstr='-grad %s',
          mandatory=True,
          position=1,
          desc=
          'Gradient encoding, supplied as a 4xN text file with each line is in the format [ X Y Z b ], where [ X Y Z ] describe the direction of the applied gradient, and b gives the b-value in units (1000 s/mm^2). See FSL2MRTrix'
      )
      maximum_harmonic_order = traits.Float(
          argstr='-lmax %s',
          desc=
          'set the maximum harmonic order for the output series. By default, the program will use the highest possible lmax given the number of diffusion-weighted images.'
      )
      normalise = traits.Bool(
          argstr='-normalise',
          position=3,
          desc="normalise the DW signal to the b=0 image")
  
  
  class DWI2SphericalHarmonicsImageOutputSpec(TraitedSpec):
      spherical_harmonics_image = File(
          exists=True, desc='Spherical harmonics image')
  
  
  class DWI2SphericalHarmonicsImage(CommandLine):
      """
      Convert base diffusion-weighted images to their spherical harmonic representation.
  
      This program outputs the spherical harmonic decomposition for the set measured signal attenuations.
      The signal attenuations are calculated by identifying the b-zero images from the diffusion encoding supplied
      (i.e. those with zero as the b-value), and dividing the remaining signals by the mean b-zero signal intensity.
      The spherical harmonic decomposition is then calculated by least-squares linear fitting.
      Note that this program makes use of implied symmetries in the diffusion profile.
  
      First, the fact the signal attenuation profile is real implies that it has conjugate symmetry,
      i.e. Y(l,-m) = Y(l,m)* (where * denotes the complex conjugate). Second, the diffusion profile should be
      antipodally symmetric (i.e. S(x) = S(-x)), implying that all odd l components should be zero. Therefore,
      this program only computes the even elements.
  
      Note that the spherical harmonics equations used here differ slightly from those conventionally used,
      in that the (-1)^m factor has been omitted. This should be taken into account in all subsequent calculations.
  
      Each volume in the output image corresponds to a different spherical harmonic component, according to the following convention:
  
      * [0] Y(0,0)
      * [1] Im {Y(2,2)}
      * [2] Im {Y(2,1)}
      * [3] Y(2,0)
      * [4] Re {Y(2,1)}
      * [5] Re {Y(2,2)}
      * [6] Im {Y(4,4)}
      * [7] Im {Y(4,3)}
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> dwi2SH = mrt.DWI2SphericalHarmonicsImage()
      >>> dwi2SH.inputs.in_file = 'diffusion.nii'
      >>> dwi2SH.inputs.encoding_file = 'encoding.txt'
      >>> dwi2SH.run()                                    # doctest: +SKIP
      """
      _cmd = 'dwi2SH'
      input_spec = DWI2SphericalHarmonicsImageInputSpec
      output_spec = DWI2SphericalHarmonicsImageOutputSpec
  
      def _list_outputs(self):
          outputs = self.output_spec().get()
          outputs['spherical_harmonics_image'] = self.inputs.out_filename
          if not isdefined(outputs['spherical_harmonics_image']):
              outputs['spherical_harmonics_image'] = op.abspath(
                  self._gen_outfilename())
          else:
              outputs['spherical_harmonics_image'] = op.abspath(
                  outputs['spherical_harmonics_image'])
          return outputs
  
      def _gen_filename(self, name):
          if name == 'out_filename':
              return self._gen_outfilename()
          else:
              return None
  
      def _gen_outfilename(self):
          _, name, _ = split_filename(self.inputs.in_file)
          return name + '_SH.mif'
  
  
  class ConstrainedSphericalDeconvolutionInputSpec(CommandLineInputSpec):
      in_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-3,
          desc='diffusion-weighted image')
      response_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-2,
          desc=
          'the diffusion-weighted signal response function for a single fibre population (see EstimateResponse)'
      )
      out_filename = File(
          genfile=True, argstr='%s', position=-1, desc='Output filename')
      mask_image = File(
          exists=True,
          argstr='-mask %s',
          position=2,
          desc=
          'only perform computation within the specified binary brain mask image'
      )
      encoding_file = File(
          exists=True,
          argstr='-grad %s',
          position=1,
          desc=
          'Gradient encoding, supplied as a 4xN text file with each line is in the format [ X Y Z b ], where [ X Y Z ] describe the direction of the applied gradient, and b gives the b-value in units (1000 s/mm^2). See FSL2MRTrix'
      )
      filter_file = File(
          exists=True,
          argstr='-filter %s',
          position=-2,
          desc=
          'a text file containing the filtering coefficients for each even harmonic order.'
          'the linear frequency filtering parameters used for the initial linear spherical deconvolution step (default = [ 1 1 1 0 0 ]).'
      )
  
      lambda_value = traits.Float(
          argstr='-lambda %s',
          desc=
          'the regularisation parameter lambda that controls the strength of the constraint (default = 1.0).'
      )
      maximum_harmonic_order = traits.Int(
          argstr='-lmax %s',
          desc=
          'set the maximum harmonic order for the output series. By default, the program will use the highest possible lmax given the number of diffusion-weighted images.'
      )
      threshold_value = traits.Float(
          argstr='-threshold %s',
          desc=
          'the threshold below which the amplitude of the FOD is assumed to be zero, expressed as a fraction of the mean value of the initial FOD (default = 0.1)'
      )
      iterations = traits.Int(
          argstr='-niter %s',
          desc=
          'the maximum number of iterations to perform for each voxel (default = 50)'
      )
      debug = traits.Bool(argstr='-debug', desc='Display debugging messages.')
      directions_file = File(
          exists=True,
          argstr='-directions %s',
          position=-2,
          desc=
          'a text file containing the [ el az ] pairs for the directions: Specify the directions over which to apply the non-negativity constraint (by default, the built-in 300 direction set is used)'
      )
  
      normalise = traits.Bool(
          argstr='-normalise',
          position=3,
          desc="normalise the DW signal to the b=0 image")
  
  
  class ConstrainedSphericalDeconvolutionOutputSpec(TraitedSpec):
      spherical_harmonics_image = File(
          exists=True, desc='Spherical harmonics image')
  
  
  class ConstrainedSphericalDeconvolution(CommandLine):
      """
      Perform non-negativity constrained spherical deconvolution.
  
      Note that this program makes use of implied symmetries in the diffusion profile.
      First, the fact the signal attenuation profile is real implies that it has conjugate symmetry,
      i.e. Y(l,-m) = Y(l,m)* (where * denotes the complex conjugate). Second, the diffusion profile should be
      antipodally symmetric (i.e. S(x) = S(-x)), implying that all odd l components should be zero.
      Therefore, this program only computes the even elements. 	Note that the spherical harmonics equations used here
      differ slightly from those conventionally used, in that the (-1)^m factor has been omitted. This should be taken
      into account in all subsequent calculations. Each volume in the output image corresponds to a different spherical
      harmonic component, according to the following convention:
  
      * [0] Y(0,0)
      * [1] Im {Y(2,2)}
      * [2] Im {Y(2,1)}
      * [3] Y(2,0)
      * [4] Re {Y(2,1)}
      * [5] Re {Y(2,2)}
      * [6] Im {Y(4,4)}
      * [7] Im {Y(4,3)}
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> csdeconv = mrt.ConstrainedSphericalDeconvolution()
      >>> csdeconv.inputs.in_file = 'dwi.mif'
      >>> csdeconv.inputs.encoding_file = 'encoding.txt'
      >>> csdeconv.run()                                          # doctest: +SKIP
      """
  
      _cmd = 'csdeconv'
      input_spec = ConstrainedSphericalDeconvolutionInputSpec
      output_spec = ConstrainedSphericalDeconvolutionOutputSpec
  
      def _list_outputs(self):
          outputs = self.output_spec().get()
          outputs['spherical_harmonics_image'] = self.inputs.out_filename
          if not isdefined(outputs['spherical_harmonics_image']):
              outputs['spherical_harmonics_image'] = op.abspath(
                  self._gen_outfilename())
          else:
              outputs['spherical_harmonics_image'] = op.abspath(
                  outputs['spherical_harmonics_image'])
          return outputs
  
      def _gen_filename(self, name):
          if name == 'out_filename':
              return self._gen_outfilename()
          else:
              return None
  
      def _gen_outfilename(self):
          _, name, _ = split_filename(self.inputs.in_file)
          return name + '_CSD.mif'
  
  
  class EstimateResponseForSHInputSpec(CommandLineInputSpec):
      in_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-3,
          desc='Diffusion-weighted images')
      mask_image = File(
          exists=True,
          mandatory=True,
          argstr='%s',
          position=-2,
          desc=
          'only perform computation within the specified binary brain mask image'
      )
      out_filename = File(
          genfile=True, argstr='%s', position=-1, desc='Output filename')
      encoding_file = File(
          exists=True,
          argstr='-grad %s',
          mandatory=True,
          position=1,
          desc=
          'Gradient encoding, supplied as a 4xN text file with each line is in the format [ X Y Z b ], where [ X Y Z ] describe the direction of the applied gradient, and b gives the b-value in units (1000 s/mm^2). See FSL2MRTrix'
      )
      maximum_harmonic_order = traits.Int(
          argstr='-lmax %s',
          desc=
          'set the maximum harmonic order for the output series. By default, the program will use the highest possible lmax given the number of diffusion-weighted images.'
      )
      normalise = traits.Bool(
          argstr='-normalise', desc='normalise the DW signal to the b=0 image')
      quiet = traits.Bool(
          argstr='-quiet',
          desc='Do not display information messages or progress status.')
      debug = traits.Bool(argstr='-debug', desc='Display debugging messages.')
  
  
  class EstimateResponseForSHOutputSpec(TraitedSpec):
      response = File(exists=True, desc='Spherical harmonics image')
  
  
  class EstimateResponseForSH(CommandLine):
      """
      Estimates the fibre response function for use in spherical deconvolution.
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> estresp = mrt.EstimateResponseForSH()
      >>> estresp.inputs.in_file = 'dwi.mif'
      >>> estresp.inputs.mask_image = 'dwi_WMProb.mif'
      >>> estresp.inputs.encoding_file = 'encoding.txt'
      >>> estresp.run()                                   # doctest: +SKIP
      """
      _cmd = 'estimate_response'
      input_spec = EstimateResponseForSHInputSpec
      output_spec = EstimateResponseForSHOutputSpec
  
      def _list_outputs(self):
          outputs = self.output_spec().get()
          outputs['response'] = self.inputs.out_filename
          if not isdefined(outputs['response']):
              outputs['response'] = op.abspath(self._gen_outfilename())
          else:
              outputs['response'] = op.abspath(outputs['response'])
          return outputs
  
      def _gen_filename(self, name):
          if name == 'out_filename':
              return self._gen_outfilename()
          else:
              return None
  
      def _gen_outfilename(self):
          _, name, _ = split_filename(self.inputs.in_file)
          return name + '_ER.txt'
  
  
  def concat_files(bvec_file, bval_file, invert_x, invert_y, invert_z):
      bvecs = np.loadtxt(bvec_file)
      bvals = np.loadtxt(bval_file)
      if np.shape(bvecs)[0] > np.shape(bvecs)[1]:
          bvecs = np.transpose(bvecs)
      if invert_x:
          bvecs[0, :] = -bvecs[0, :]
          iflogger.info('Inverting b-vectors in the x direction')
      if invert_y:
          bvecs[1, :] = -bvecs[1, :]
          iflogger.info('Inverting b-vectors in the y direction')
      if invert_z:
          bvecs[2, :] = -bvecs[2, :]
          iflogger.info('Inverting b-vectors in the z direction')
      iflogger.info(np.shape(bvecs))
      iflogger.info(np.shape(bvals))
      encoding = np.transpose(np.vstack((bvecs, bvals)))
      _, bvec, _ = split_filename(bvec_file)
      _, bval, _ = split_filename(bval_file)
      out_encoding_file = bvec + '_' + bval + '.txt'
      np.savetxt(out_encoding_file, encoding)
      return out_encoding_file
  
  
  class FSL2MRTrixInputSpec(TraitedSpec):
      bvec_file = File(
          exists=True, mandatory=True, desc='FSL b-vectors file (3xN text file)')
      bval_file = File(
          exists=True, mandatory=True, desc='FSL b-values file (1xN text file)')
      invert_x = traits.Bool(
          False, usedefault=True, desc='Inverts the b-vectors along the x-axis')
      invert_y = traits.Bool(
          False, usedefault=True, desc='Inverts the b-vectors along the y-axis')
      invert_z = traits.Bool(
          False, usedefault=True, desc='Inverts the b-vectors along the z-axis')
      out_encoding_file = File(genfile=True, desc='Output encoding filename')
  
  
  class FSL2MRTrixOutputSpec(TraitedSpec):
      encoding_file = File(
          desc=
          'The gradient encoding, supplied as a 4xN text file with each line is in the format [ X Y Z b ], where [ X Y Z ] describe the direction of the applied gradient'
          'and b gives the b-value in units (1000 s/mm^2).')
  
  
  class FSL2MRTrix(BaseInterface):
      """
      Converts separate b-values and b-vectors from text files (FSL style) into a
      4xN text file in which each line is in the format [ X Y Z b ], where [ X Y Z ]
      describe the direction of the applied gradient, and b gives the
      b-value in units (1000 s/mm^2).
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> fsl2mrtrix = mrt.FSL2MRTrix()
      >>> fsl2mrtrix.inputs.bvec_file = 'bvecs'
      >>> fsl2mrtrix.inputs.bval_file = 'bvals'
      >>> fsl2mrtrix.inputs.invert_y = True
      >>> fsl2mrtrix.run()                                # doctest: +SKIP
      """
      input_spec = FSL2MRTrixInputSpec
      output_spec = FSL2MRTrixOutputSpec
  
      def _run_interface(self, runtime):
          encoding = concat_files(self.inputs.bvec_file, self.inputs.bval_file,
                                  self.inputs.invert_x, self.inputs.invert_y,
                                  self.inputs.invert_z)
          return runtime
  
      def _list_outputs(self):
          outputs = self.output_spec().get()
          outputs['encoding_file'] = op.abspath(
              self._gen_filename('out_encoding_file'))
          return outputs
  
      def _gen_filename(self, name):
          if name == 'out_encoding_file':
              return self._gen_outfilename()
          else:
              return None
  
      def _gen_outfilename(self):
          _, bvec, _ = split_filename(self.inputs.bvec_file)
          _, bval, _ = split_filename(self.inputs.bval_file)
          return bvec + '_' + bval + '.txt'
  
  
  class GenerateDirectionsInputSpec(CommandLineInputSpec):
      num_dirs = traits.Int(
          mandatory=True,
          argstr='%s',
          position=-2,
          desc='the number of directions to generate.')
  
      power = traits.Float(
          argstr='-power %s',
          desc='specify exponent to use for repulsion power law.')
      niter = traits.Int(
          argstr='-niter %s',
          desc='specify the maximum number of iterations to perform.')
      display_info = traits.Bool(
          argstr='-info', desc='Display information messages.')
      quiet_display = traits.Bool(
          argstr='-quiet',
          desc='do not display information messages or progress status.')
      display_debug = traits.Bool(
          argstr='-debug', desc='Display debugging messages.')
      out_file = File(
          name_source=['num_dirs'],
          name_template='directions_%d.txt',
          argstr='%s',
          hash_files=False,
          position=-1,
          desc='the text file to write the directions to, as [ az el ] pairs.')
  
  
  class GenerateDirectionsOutputSpec(TraitedSpec):
      out_file = File(exists=True, desc='directions file')
  
  
  class GenerateDirections(CommandLine):
      """
      generate a set of directions evenly distributed over a hemisphere.
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> gendir = mrt.GenerateDirections()
      >>> gendir.inputs.num_dirs = 300
      >>> gendir.run()                                          # doctest: +SKIP
      """
  
      _cmd = 'gendir'
      input_spec = GenerateDirectionsInputSpec
      output_spec = GenerateDirectionsOutputSpec
  
  
  class FindShPeaksInputSpec(CommandLineInputSpec):
      in_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-3,
          desc='the input image of SH coefficients.')
      directions_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-2,
          desc='the set of directions to use as seeds for the peak finding')
      peaks_image = File(
          exists=True,
          argstr='-peaks %s',
          desc=
          'the program will try to find the peaks that most closely match those in the image provided'
      )
      num_peaks = traits.Int(
          argstr='-num %s', desc='the number of peaks to extract (default is 3)')
      peak_directions = traits.List(
          traits.Float,
          argstr='-direction %s',
          sep=' ',
          minlen=2,
          maxlen=2,
          desc=
          'phi theta.  the direction of a peak to estimate. The algorithm will attempt to find the same number of peaks as have been specified using this option '
          ' phi: the azimuthal angle of the direction (in degrees). theta: the elevation angle of the direction (in degrees, from the vertical z-axis)'
      )
      peak_threshold = traits.Float(
          argstr='-threshold %s',
          desc=
          'only peak amplitudes greater than the threshold will be considered')
      display_info = traits.Bool(
          argstr='-info', desc='Display information messages.')
      quiet_display = traits.Bool(
          argstr='-quiet',
          desc='do not display information messages or progress status.')
      display_debug = traits.Bool(
          argstr='-debug', desc='Display debugging messages.')
      out_file = File(
          name_template="%s_peak_dirs.mif",
          keep_extension=False,
          argstr='%s',
          hash_files=False,
          position=-1,
          desc=
          'the output image. Each volume corresponds to the x, y & z component of each peak direction vector in turn',
          name_source=["in_file"])
  
  
  class FindShPeaksOutputSpec(TraitedSpec):
      out_file = File(exists=True, desc='Peak directions image')
  
  
  class FindShPeaks(CommandLine):
      """
      identify the orientations of the N largest peaks of a SH profile
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> shpeaks = mrt.FindShPeaks()
      >>> shpeaks.inputs.in_file = 'csd.mif'
      >>> shpeaks.inputs.directions_file = 'dirs.txt'
      >>> shpeaks.inputs.num_peaks = 2
      >>> shpeaks.run()                                          # doctest: +SKIP
      """
  
      _cmd = 'find_SH_peaks'
      input_spec = FindShPeaksInputSpec
      output_spec = FindShPeaksOutputSpec
  
  
  class Directions2AmplitudeInputSpec(CommandLineInputSpec):
      in_file = File(
          exists=True,
          argstr='%s',
          mandatory=True,
          position=-2,
          desc=
          'the input directions image. Each volume corresponds to the x, y & z component of each direction vector in turn.'
      )
      peaks_image = File(
          exists=True,
          argstr='-peaks %s',
          desc=
          'the program will try to find the peaks that most closely match those in the image provided'
      )
      num_peaks = traits.Int(
          argstr='-num %s', desc='the number of peaks to extract (default is 3)')
      peak_directions = traits.List(
          traits.Float,
          argstr='-direction %s',
          sep=' ',
          minlen=2,
          maxlen=2,
          desc=
          'phi theta.  the direction of a peak to estimate. The algorithm will attempt to find the same number of peaks as have been specified using this option '
          ' phi: the azimuthal angle of the direction (in degrees). theta: the elevation angle of the direction (in degrees, from the vertical z-axis)'
      )
      display_info = traits.Bool(
          argstr='-info', desc='Display information messages.')
      quiet_display = traits.Bool(
          argstr='-quiet',
          desc='do not display information messages or progress status.')
      display_debug = traits.Bool(
          argstr='-debug', desc='Display debugging messages.')
      out_file = File(
          name_template="%s_amplitudes.mif",
          keep_extension=False,
          argstr='%s',
          hash_files=False,
          position=-1,
          desc='the output amplitudes image',
          name_source=["in_file"])
  
  
  class Directions2AmplitudeOutputSpec(TraitedSpec):
      out_file = File(exists=True, desc='amplitudes image')
  
  
  class Directions2Amplitude(CommandLine):
      """
      convert directions image to amplitudes
  
      Example
      -------
  
      >>> import nipype.interfaces.mrtrix as mrt
      >>> amplitudes = mrt.Directions2Amplitude()
      >>> amplitudes.inputs.in_file = 'peak_directions.mif'
      >>> amplitudes.run()                                          # doctest: +SKIP
      """
  
      _cmd = 'dir2amp'
      input_spec = Directions2AmplitudeInputSpec
      output_spec = Directions2AmplitudeOutputSpec
  