text: /* Created by Language version: 7.7.0 */
  /* NOT VECTORIZED */
  #define NRN_VECTORIZED 0
  #include <stdio.h>
  #include <stdlib.h>
  #include <math.h>
  #include "scoplib_ansi.h"
  #undef PI
  #define nil 0
  #include "md1redef.h"
  #include "section.h"
  #include "nrniv_mf.h"
  #include "md2redef.h"
   
  #if METHOD3
  extern int _method3;
  #endif
  
  #if !NRNGPU
  #undef exp
  #define exp hoc_Exp
  extern double hoc_Exp(double);
  #endif
   
  #define nrn_init _nrn_init__ProbAMPANMDA
  #define _nrn_initial _nrn_initial__ProbAMPANMDA
  #define nrn_cur _nrn_cur__ProbAMPANMDA
  #define _nrn_current _nrn_current__ProbAMPANMDA
  #define nrn_jacob _nrn_jacob__ProbAMPANMDA
  #define nrn_state _nrn_state__ProbAMPANMDA
  #define _net_receive _net_receive__ProbAMPANMDA 
  #define setRNG setRNG__ProbAMPANMDA 
  #define state state__ProbAMPANMDA 
   
  #define _threadargscomma_ /**/
  #define _threadargsprotocomma_ /**/
  #define _threadargs_ /**/
  #define _threadargsproto_ /**/
   	/*SUPPRESS 761*/
  	/*SUPPRESS 762*/
  	/*SUPPRESS 763*/
  	/*SUPPRESS 765*/
  	 extern double *getarg();
   static double *_p; static Datum *_ppvar;
   
  #define t nrn_threads->_t
  #define dt nrn_threads->_dt
  #define tau_r_AMPA _p[0]
  #define tau_d_AMPA _p[1]
  #define tau_r_NMDA _p[2]
  #define tau_d_NMDA _p[3]
  #define Use _p[4]
  #define Dep _p[5]
  #define Fac _p[6]
  #define e _p[7]
  #define gmax _p[8]
  #define u0 _p[9]
  #define weight_factor_NMDA _p[10]
  #define i _p[11]
  #define i_AMPA _p[12]
  #define i_NMDA _p[13]
  #define g_AMPA _p[14]
  #define g_NMDA _p[15]
  #define A_AMPA _p[16]
  #define B_AMPA _p[17]
  #define A_NMDA _p[18]
  #define B_NMDA _p[19]
  #define factor_AMPA _p[20]
  #define factor_NMDA _p[21]
  #define DA_AMPA _p[22]
  #define DB_AMPA _p[23]
  #define DA_NMDA _p[24]
  #define DB_NMDA _p[25]
  #define _g _p[26]
  #define _tsav _p[27]
  #define _nd_area  *_ppvar[0]._pval
  #define rng	*_ppvar[2]._pval
  #define _p_rng	_ppvar[2]._pval
   
  #if MAC
  #if !defined(v)
  #define v _mlhv
  #endif
  #if !defined(h)
  #define h _mlhh
  #endif
  #endif
   
  #if defined(__cplusplus)
  extern "C" {
  #endif
   static int hoc_nrnpointerindex =  2;
   /* external NEURON variables */
   /* declaration of user functions */
   static double _hoc_erand();
   static double _hoc_setRNG();
   static int _mechtype;
  extern void _nrn_cacheloop_reg(int, int);
  extern void hoc_register_prop_size(int, int, int);
  extern void hoc_register_limits(int, HocParmLimits*);
  extern void hoc_register_units(int, HocParmUnits*);
  extern void nrn_promote(Prop*, int, int);
  extern Memb_func* memb_func;
   
  #define NMODL_TEXT 1
  #if NMODL_TEXT
  static const char* nmodl_file_text;
  static const char* nmodl_filename;
  extern void hoc_reg_nmodl_text(int, const char*);
  extern void hoc_reg_nmodl_filename(int, const char*);
  #endif
  
   extern Prop* nrn_point_prop_;
   static int _pointtype;
   static void* _hoc_create_pnt(_ho) Object* _ho; { void* create_point_process();
   return create_point_process(_pointtype, _ho);
  }
   static void _hoc_destroy_pnt();
   static double _hoc_loc_pnt(_vptr) void* _vptr; {double loc_point_process();
   return loc_point_process(_pointtype, _vptr);
  }
   static double _hoc_has_loc(_vptr) void* _vptr; {double has_loc_point();
   return has_loc_point(_vptr);
  }
   static double _hoc_get_loc_pnt(_vptr)void* _vptr; {
   double get_loc_point_process(); return (get_loc_point_process(_vptr));
  }
   extern void _nrn_setdata_reg(int, void(*)(Prop*));
   static void _setdata(Prop* _prop) {
   _p = _prop->param; _ppvar = _prop->dparam;
   }
   static void _hoc_setdata(void* _vptr) { Prop* _prop;
   _prop = ((Point_process*)_vptr)->_prop;
     _setdata(_prop);
   }
   /* connect user functions to hoc names */
   static VoidFunc hoc_intfunc[] = {
   0,0
  };
   static Member_func _member_func[] = {
   "loc", _hoc_loc_pnt,
   "has_loc", _hoc_has_loc,
   "get_loc", _hoc_get_loc_pnt,
   "erand", _hoc_erand,
   "setRNG", _hoc_setRNG,
   0, 0
  };
  #define erand erand_ProbAMPANMDA
   extern double erand( );
   /* declare global and static user variables */
  #define mggate mggate_ProbAMPANMDA
   double mggate = 0;
  #define mg mg_ProbAMPANMDA
   double mg = 1;
   /* some parameters have upper and lower limits */
   static HocParmLimits _hoc_parm_limits[] = {
   0,0,0
  };
   static HocParmUnits _hoc_parm_units[] = {
   "mg_ProbAMPANMDA", "mM",
   "tau_r_AMPA", "ms",
   "tau_d_AMPA", "ms",
   "tau_r_NMDA", "ms",
   "tau_d_NMDA", "ms",
   "Use", "1",
   "Dep", "ms",
   "Fac", "ms",
   "e", "mV",
   "gmax", "uS",
   "i", "nA",
   "i_AMPA", "nA",
   "i_NMDA", "nA",
   "g_AMPA", "uS",
   "g_NMDA", "uS",
   0,0
  };
   static double A_NMDA0 = 0;
   static double A_AMPA0 = 0;
   static double B_NMDA0 = 0;
   static double B_AMPA0 = 0;
   static double delta_t = 0.01;
   static double v = 0;
   /* connect global user variables to hoc */
   static DoubScal hoc_scdoub[] = {
   "mg_ProbAMPANMDA", &mg_ProbAMPANMDA,
   "mggate_ProbAMPANMDA", &mggate_ProbAMPANMDA,
   0,0
  };
   static DoubVec hoc_vdoub[] = {
   0,0,0
  };
   static double _sav_indep;
   static void nrn_alloc(Prop*);
  static void  nrn_init(_NrnThread*, _Memb_list*, int);
  static void nrn_state(_NrnThread*, _Memb_list*, int);
   static void nrn_cur(_NrnThread*, _Memb_list*, int);
  static void  nrn_jacob(_NrnThread*, _Memb_list*, int);
   static void _hoc_destroy_pnt(_vptr) void* _vptr; {
     destroy_point_process(_vptr);
  }
   
  static int _ode_count(int);
  static void _ode_map(int, double**, double**, double*, Datum*, double*, int);
  static void _ode_spec(_NrnThread*, _Memb_list*, int);
  static void _ode_matsol(_NrnThread*, _Memb_list*, int);
   
  #define _cvode_ieq _ppvar[3]._i
   static void _ode_matsol_instance1(_threadargsproto_);
   /* connect range variables in _p that hoc is supposed to know about */
   static const char *_mechanism[] = {
   "7.7.0",
  "ProbAMPANMDA",
   "tau_r_AMPA",
   "tau_d_AMPA",
   "tau_r_NMDA",
   "tau_d_NMDA",
   "Use",
   "Dep",
   "Fac",
   "e",
   "gmax",
   "u0",
   "weight_factor_NMDA",
   0,
   "i",
   "i_AMPA",
   "i_NMDA",
   "g_AMPA",
   "g_NMDA",
   0,
   "A_AMPA",
   "B_AMPA",
   "A_NMDA",
   "B_NMDA",
   0,
   "rng",
   0};
   
  extern Prop* need_memb(Symbol*);
  
  static void nrn_alloc(Prop* _prop) {
  	Prop *prop_ion;
  	double *_p; Datum *_ppvar;
    if (nrn_point_prop_) {
  	_prop->_alloc_seq = nrn_point_prop_->_alloc_seq;
  	_p = nrn_point_prop_->param;
  	_ppvar = nrn_point_prop_->dparam;
   }else{
   	_p = nrn_prop_data_alloc(_mechtype, 28, _prop);
   	/*initialize range parameters*/
   	tau_r_AMPA = 0.2;
   	tau_d_AMPA = 1.7;
   	tau_r_NMDA = 0.29;
   	tau_d_NMDA = 43;
   	Use = 1;
   	Dep = 100;
   	Fac = 10;
   	e = 0;
   	gmax = 0.001;
   	u0 = 0;
   	weight_factor_NMDA = 1;
    }
   	_prop->param = _p;
   	_prop->param_size = 28;
    if (!nrn_point_prop_) {
   	_ppvar = nrn_prop_datum_alloc(_mechtype, 4, _prop);
    }
   	_prop->dparam = _ppvar;
   	/*connect ionic variables to this model*/
   
  }
   static void _initlists();
    /* some states have an absolute tolerance */
   static Symbol** _atollist;
   static HocStateTolerance _hoc_state_tol[] = {
   0,0
  };
   static void _net_receive(Point_process*, double*, double);
   static void _net_init(Point_process*, double*, double);
   extern Symbol* hoc_lookup(const char*);
  extern void _nrn_thread_reg(int, int, void(*)(Datum*));
  extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
  extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
  extern void _cvode_abstol( Symbol**, double*, int);
  
   void _ProbAMPANMDA_reg() {
  	int _vectorized = 0;
    _initlists();
   	_pointtype = point_register_mech(_mechanism,
  	 nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init,
  	 hoc_nrnpointerindex, 0,
  	 _hoc_create_pnt, _hoc_destroy_pnt, _member_func);
   _mechtype = nrn_get_mechtype(_mechanism[1]);
       _nrn_setdata_reg(_mechtype, _setdata);
   #if NMODL_TEXT
    hoc_reg_nmodl_text(_mechtype, nmodl_file_text);
    hoc_reg_nmodl_filename(_mechtype, nmodl_filename);
  #endif
    hoc_register_prop_size(_mechtype, 28, 4);
    hoc_register_dparam_semantics(_mechtype, 0, "area");
    hoc_register_dparam_semantics(_mechtype, 1, "pntproc");
    hoc_register_dparam_semantics(_mechtype, 2, "pointer");
    hoc_register_dparam_semantics(_mechtype, 3, "cvodeieq");
   	hoc_register_cvode(_mechtype, _ode_count, _ode_map, _ode_spec, _ode_matsol);
   	hoc_register_tolerance(_mechtype, _hoc_state_tol, &_atollist);
   pnt_receive[_mechtype] = _net_receive;
   pnt_receive_init[_mechtype] = _net_init;
   pnt_receive_size[_mechtype] = 6;
   	hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
   	ivoc_help("help ?1 ProbAMPANMDA /Users/frankmazza/frankm/LFPy/mod/x86_64/ProbAMPANMDA.mod\n");
   hoc_register_limits(_mechtype, _hoc_parm_limits);
   hoc_register_units(_mechtype, _hoc_parm_units);
   }
  static int _reset;
  static char *modelname = "AMPA and NMDA receptor with presynaptic short-term plasticity ";
  
  static int error;
  static int _ninits = 0;
  static int _match_recurse=1;
  static void _modl_cleanup(){ _match_recurse=1;}
  static int setRNG();
   
  static int _ode_spec1(_threadargsproto_);
  /*static int _ode_matsol1(_threadargsproto_);*/
   static int _slist1[4], _dlist1[4];
   static int state(_threadargsproto_);
   
  /*VERBATIM*/
  
  #include<stdlib.h>
  #include<stdio.h>
  #include<math.h>
  
  double nrn_random_pick(void* r);
  void* nrn_random_arg(int argpos);
  
   
  /*CVODE*/
   static int _ode_spec1 () {_reset=0;
   {
     DA_AMPA = - A_AMPA / tau_r_AMPA ;
     DB_AMPA = - B_AMPA / tau_d_AMPA ;
     DA_NMDA = - A_NMDA / tau_r_NMDA ;
     DB_NMDA = - B_NMDA / tau_d_NMDA ;
     }
   return _reset;
  }
   static int _ode_matsol1 () {
   DA_AMPA = DA_AMPA  / (1. - dt*( ( - 1.0 ) / tau_r_AMPA )) ;
   DB_AMPA = DB_AMPA  / (1. - dt*( ( - 1.0 ) / tau_d_AMPA )) ;
   DA_NMDA = DA_NMDA  / (1. - dt*( ( - 1.0 ) / tau_r_NMDA )) ;
   DB_NMDA = DB_NMDA  / (1. - dt*( ( - 1.0 ) / tau_d_NMDA )) ;
    return 0;
  }
   /*END CVODE*/
   static int state () {_reset=0;
   {
      A_AMPA = A_AMPA + (1. - exp(dt*(( - 1.0 ) / tau_r_AMPA)))*(- ( 0.0 ) / ( ( - 1.0 ) / tau_r_AMPA ) - A_AMPA) ;
      B_AMPA = B_AMPA + (1. - exp(dt*(( - 1.0 ) / tau_d_AMPA)))*(- ( 0.0 ) / ( ( - 1.0 ) / tau_d_AMPA ) - B_AMPA) ;
      A_NMDA = A_NMDA + (1. - exp(dt*(( - 1.0 ) / tau_r_NMDA)))*(- ( 0.0 ) / ( ( - 1.0 ) / tau_r_NMDA ) - A_NMDA) ;
      B_NMDA = B_NMDA + (1. - exp(dt*(( - 1.0 ) / tau_d_NMDA)))*(- ( 0.0 ) / ( ( - 1.0 ) / tau_d_NMDA ) - B_NMDA) ;
     }
    return 0;
  }
   
  static void _net_receive (_pnt, _args, _lflag) Point_process* _pnt; double* _args; double _lflag; 
  {    _p = _pnt->_prop->param; _ppvar = _pnt->_prop->dparam;
    if (_tsav > t){ extern char* hoc_object_name(); hoc_execerror(hoc_object_name(_pnt->ob), ":Event arrived out of order. Must call ParallelContext.set_maxstep AFTER assigning minimum NetCon.delay");}
   _tsav = t; {
     if ( Fac > 0.0 ) {
       _args[4] = _args[4] * exp ( - ( t - _args[5] ) / Fac ) ;
       }
     else {
       _args[4] = Use ;
       }
     if ( Fac > 0.0 ) {
       _args[4] = _args[4] + Use * ( 1.0 - _args[4] ) ;
       }
     _args[2] = 1.0 - ( 1.0 - _args[1] ) * exp ( - ( t - _args[5] ) / Dep ) ;
     _args[3] = _args[4] * _args[2] ;
     _args[2] = _args[2] - _args[4] * _args[2] ;
     if ( erand ( _threadargs_ ) < _args[3] ) {
       _args[5] = t ;
       _args[1] = _args[2] ;
         if (nrn_netrec_state_adjust && !cvode_active_){
      /* discon state adjustment for cnexp case (rate uses no local variable) */
      double __state = A_AMPA;
      double __primary = (A_AMPA + _args[0] * factor_AMPA) - __state;
       __primary += ( 1. - exp( 0.5*dt*( ( - 1.0 ) / tau_r_AMPA ) ) )*( - ( 0.0 ) / ( ( - 1.0 ) / tau_r_AMPA ) - __primary );
      A_AMPA += __primary;
    } else {
   A_AMPA = A_AMPA + _args[0] * factor_AMPA ;
         }
     if (nrn_netrec_state_adjust && !cvode_active_){
      /* discon state adjustment for cnexp case (rate uses no local variable) */
      double __state = B_AMPA;
      double __primary = (B_AMPA + _args[0] * factor_AMPA) - __state;
       __primary += ( 1. - exp( 0.5*dt*( ( - 1.0 ) / tau_d_AMPA ) ) )*( - ( 0.0 ) / ( ( - 1.0 ) / tau_d_AMPA ) - __primary );
      B_AMPA += __primary;
    } else {
   B_AMPA = B_AMPA + _args[0] * factor_AMPA ;
         }
     if (nrn_netrec_state_adjust && !cvode_active_){
      /* discon state adjustment for cnexp case (rate uses no local variable) */
      double __state = A_NMDA;
      double __primary = (A_NMDA + _args[0] * weight_factor_NMDA * factor_NMDA) - __state;
       __primary += ( 1. - exp( 0.5*dt*( ( - 1.0 ) / tau_r_NMDA ) ) )*( - ( 0.0 ) / ( ( - 1.0 ) / tau_r_NMDA ) - __primary );
      A_NMDA += __primary;
    } else {
   A_NMDA = A_NMDA + _args[0] * weight_factor_NMDA * factor_NMDA ;
         }
     if (nrn_netrec_state_adjust && !cvode_active_){
      /* discon state adjustment for cnexp case (rate uses no local variable) */
      double __state = B_NMDA;
      double __primary = (B_NMDA + _args[0] * weight_factor_NMDA * factor_NMDA) - __state;
       __primary += ( 1. - exp( 0.5*dt*( ( - 1.0 ) / tau_d_NMDA ) ) )*( - ( 0.0 ) / ( ( - 1.0 ) / tau_d_NMDA ) - __primary );
      B_NMDA += __primary;
    } else {
   B_NMDA = B_NMDA + _args[0] * weight_factor_NMDA * factor_NMDA ;
         }
   }
     } }
   
  static void _net_init(Point_process* _pnt, double* _args, double _lflag) {
      _args[1] = 1.0 ;
     _args[4] = u0 ;
     _args[5] = t ;
     }
   
  static int  setRNG (  ) {
     
  /*VERBATIM*/
      {
          /**
           * This function takes a NEURON Random object declared in hoc and makes it usable by this mod file.
           * Note that this method is taken from Brett paper as used by netstim.hoc and netstim.mod
           * which points out that the Random must be in negexp(1) mode
           */
          void** pv = (void**)(&_p_rng);
          if( ifarg(1)) {
              *pv = nrn_random_arg(1);
          } else {
              *pv = (void*)0;
          }
      }
    return 0; }
   
  static double _hoc_setRNG(void* _vptr) {
   double _r;
      _hoc_setdata(_vptr);
   _r = 1.;
   setRNG (  );
   return(_r);
  }
   
  double erand (  ) {
     double _lerand;
   
  /*VERBATIM*/
  	    //FILE *fi;
          double value;
          if (_p_rng) {
                  /*
                  :Supports separate independent but reproducible streams for
                  : each instance. However, the corresponding hoc Random
                  : distribution MUST be set to Random.negexp(1)
                  */
                  value = nrn_random_pick(_p_rng);
  		        //fi = fopen("RandomStreamMCellRan4.txt", "w");
                  //fprintf(fi,"random stream for this simulation = %lf\n",value);
                  //printf("random stream for this simulation = %lf\n",value);
                  return value;
          }else{
   _lerand = exprand ( 1.0 ) ;
     
  /*VERBATIM*/
          }
   
  return _lerand;
   }
   
  static double _hoc_erand(void* _vptr) {
   double _r;
      _hoc_setdata(_vptr);
   _r =  erand (  );
   return(_r);
  }
   
  static int _ode_count(int _type){ return 4;}
   
  static void _ode_spec(_NrnThread* _nt, _Memb_list* _ml, int _type) {
     Datum* _thread;
     Node* _nd; double _v; int _iml, _cntml;
    _cntml = _ml->_nodecount;
    _thread = _ml->_thread;
    for (_iml = 0; _iml < _cntml; ++_iml) {
      _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
      _nd = _ml->_nodelist[_iml];
      v = NODEV(_nd);
       _ode_spec1 ();
   }}
   
  static void _ode_map(int _ieq, double** _pv, double** _pvdot, double* _pp, Datum* _ppd, double* _atol, int _type) { 
   	int _i; _p = _pp; _ppvar = _ppd;
  	_cvode_ieq = _ieq;
  	for (_i=0; _i < 4; ++_i) {
  		_pv[_i] = _pp + _slist1[_i];  _pvdot[_i] = _pp + _dlist1[_i];
  		_cvode_abstol(_atollist, _atol, _i);
  	}
   }
   
  static void _ode_matsol_instance1(_threadargsproto_) {
   _ode_matsol1 ();
   }
   
  static void _ode_matsol(_NrnThread* _nt, _Memb_list* _ml, int _type) {
     Datum* _thread;
     Node* _nd; double _v; int _iml, _cntml;
    _cntml = _ml->_nodecount;
    _thread = _ml->_thread;
    for (_iml = 0; _iml < _cntml; ++_iml) {
      _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
      _nd = _ml->_nodelist[_iml];
      v = NODEV(_nd);
   _ode_matsol_instance1(_threadargs_);
   }}
  
  static void initmodel() {
    int _i; double _save;_ninits++;
   _save = t;
   t = 0.0;
  {
    A_NMDA = A_NMDA0;
    A_AMPA = A_AMPA0;
    B_NMDA = B_NMDA0;
    B_AMPA = B_AMPA0;
   {
     double _ltp_AMPA , _ltp_NMDA ;
   A_AMPA = 0.0 ;
     B_AMPA = 0.0 ;
     A_NMDA = 0.0 ;
     B_NMDA = 0.0 ;
     _ltp_AMPA = ( tau_r_AMPA * tau_d_AMPA ) / ( tau_d_AMPA - tau_r_AMPA ) * log ( tau_d_AMPA / tau_r_AMPA ) ;
     _ltp_NMDA = ( tau_r_NMDA * tau_d_NMDA ) / ( tau_d_NMDA - tau_r_NMDA ) * log ( tau_d_NMDA / tau_r_NMDA ) ;
     factor_AMPA = - exp ( - _ltp_AMPA / tau_r_AMPA ) + exp ( - _ltp_AMPA / tau_d_AMPA ) ;
     factor_AMPA = 1.0 / factor_AMPA ;
     factor_NMDA = - exp ( - _ltp_NMDA / tau_r_NMDA ) + exp ( - _ltp_NMDA / tau_d_NMDA ) ;
     factor_NMDA = 1.0 / factor_NMDA ;
     }
    _sav_indep = t; t = _save;
  
  }
  }
  
  static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
  Node *_nd; double _v; int* _ni; int _iml, _cntml;
  #if CACHEVEC
      _ni = _ml->_nodeindices;
  #endif
  _cntml = _ml->_nodecount;
  for (_iml = 0; _iml < _cntml; ++_iml) {
   _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
   _tsav = -1e20;
  #if CACHEVEC
    if (use_cachevec) {
      _v = VEC_V(_ni[_iml]);
    }else
  #endif
    {
      _nd = _ml->_nodelist[_iml];
      _v = NODEV(_nd);
    }
   v = _v;
   initmodel();
  }}
  
  static double _nrn_current(double _v){double _current=0.;v=_v;{ {
     mggate = 1.0 / ( 1.0 + exp ( 0.062 * - ( v ) ) * ( mg / 3.57 ) ) ;
     g_AMPA = gmax * ( B_AMPA - A_AMPA ) ;
     g_NMDA = gmax * ( B_NMDA - A_NMDA ) * mggate ;
     i_AMPA = g_AMPA * ( v - e ) ;
     i_NMDA = g_NMDA * ( v - e ) ;
     i = i_AMPA + i_NMDA ;
     }
   _current += i;
   _current += i_AMPA;
   _current += i_NMDA;
  
  } return _current;
  }
  
  static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type){
  Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
  #if CACHEVEC
      _ni = _ml->_nodeindices;
  #endif
  _cntml = _ml->_nodecount;
  for (_iml = 0; _iml < _cntml; ++_iml) {
   _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
  #if CACHEVEC
    if (use_cachevec) {
      _v = VEC_V(_ni[_iml]);
    }else
  #endif
    {
      _nd = _ml->_nodelist[_iml];
      _v = NODEV(_nd);
    }
   _g = _nrn_current(_v + .001);
   	{ _rhs = _nrn_current(_v);
   	}
   _g = (_g - _rhs)/.001;
   _g *=  1.e2/(_nd_area);
   _rhs *= 1.e2/(_nd_area);
  #if CACHEVEC
    if (use_cachevec) {
  	VEC_RHS(_ni[_iml]) -= _rhs;
    }else
  #endif
    {
  	NODERHS(_nd) -= _rhs;
    }
   
  }}
  
  static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type){
  Node *_nd; int* _ni; int _iml, _cntml;
  #if CACHEVEC
      _ni = _ml->_nodeindices;
  #endif
  _cntml = _ml->_nodecount;
  for (_iml = 0; _iml < _cntml; ++_iml) {
   _p = _ml->_data[_iml];
  #if CACHEVEC
    if (use_cachevec) {
  	VEC_D(_ni[_iml]) += _g;
    }else
  #endif
    {
       _nd = _ml->_nodelist[_iml];
  	NODED(_nd) += _g;
    }
   
  }}
  
  static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type){
  Node *_nd; double _v = 0.0; int* _ni; int _iml, _cntml;
  #if CACHEVEC
      _ni = _ml->_nodeindices;
  #endif
  _cntml = _ml->_nodecount;
  for (_iml = 0; _iml < _cntml; ++_iml) {
   _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
   _nd = _ml->_nodelist[_iml];
  #if CACHEVEC
    if (use_cachevec) {
      _v = VEC_V(_ni[_iml]);
    }else
  #endif
    {
      _nd = _ml->_nodelist[_iml];
      _v = NODEV(_nd);
    }
   v=_v;
  {
   { error =  state();
   if(error){fprintf(stderr,"at line 102 in file ProbAMPANMDA.mod:\n        SOLVE state METHOD cnexp\n"); nrn_complain(_p); abort_run(error);}
   }}}
  
  }
  
  static void terminal(){}
  
  static void _initlists() {
   int _i; static int _first = 1;
    if (!_first) return;
   _slist1[0] = &(A_AMPA) - _p;  _dlist1[0] = &(DA_AMPA) - _p;
   _slist1[1] = &(B_AMPA) - _p;  _dlist1[1] = &(DB_AMPA) - _p;
   _slist1[2] = &(A_NMDA) - _p;  _dlist1[2] = &(DA_NMDA) - _p;
   _slist1[3] = &(B_NMDA) - _p;  _dlist1[3] = &(DB_NMDA) - _p;
  _first = 0;
  }
  
  #if NMODL_TEXT
  static const char* nmodl_filename = "/Users/frankmazza/frankm/LFPy/mod/ProbAMPANMDA.mod";
  static const char* nmodl_file_text = 
    "TITLE AMPA and NMDA receptor with presynaptic short-term plasticity \n"
    "\n"
    "\n"
    "COMMENT\n"
    "AMPA and NMDA receptor conductance using a dual-exponential profile\n"
    "presynaptic short-term plasticity based on Fuhrmann et al. 2002\n"
    "Implemented by Srikanth Ramaswamy, Blue Brain Project, July 2009\n"
    "Etay: changed weight to be equal for NMDA and AMPA, gmax accessible in Neuron\n"
    "Tuomo: allowed different weights for AMPA and NMDA\n"
    "\n"
    "ENDCOMMENT\n"
    "\n"
    "\n"
    "NEURON {\n"
    "\n"
    "        POINT_PROCESS ProbAMPANMDA \n"
    "        RANGE tau_r_AMPA, tau_d_AMPA, tau_r_NMDA, tau_d_NMDA\n"
    "        RANGE Use, u, Dep, Fac, u0, weight_factor_NMDA\n"
    "        RANGE i, i_AMPA, i_NMDA, g_AMPA, g_NMDA, e, gmax\n"
    "        NONSPECIFIC_CURRENT i, i_AMPA,i_NMDA\n"
    "	POINTER rng\n"
    "}\n"
    "\n"
    "PARAMETER {\n"
    "\n"
    "        tau_r_AMPA = 0.2   (ms)  : dual-exponential conductance profile\n"
    "        tau_d_AMPA = 1.7    (ms)  : IMPORTANT: tau_r < tau_d\n"
    "	tau_r_NMDA = 0.29   (ms) : dual-exponential conductance profile\n"
    "        tau_d_NMDA = 43     (ms) : IMPORTANT: tau_r < tau_d\n"
    "        Use = 1.0   (1)   : Utilization of synaptic efficacy (just initial values! Use, Dep and Fac are overwritten by BlueBuilder assigned values) \n"
    "        Dep = 100   (ms)  : relaxation time constant from depression\n"
    "        Fac = 10   (ms)  :  relaxation time constant from facilitation\n"
    "        e = 0     (mV)  : AMPA and NMDA reversal potential\n"
    "	mg = 1   (mM)  : initial concentration of mg2+\n"
    "        mggate\n"
    "    	gmax = .001 (uS) : weight conversion factor (from nS to uS)\n"
    "    	u0 = 0 :initial value of u, which is the running value of Use\n"
    "        weight_factor_NMDA = 1\n"
    "}\n"
    "\n"
    "COMMENT\n"
    "The Verbatim block is needed to generate random nos. from a uniform distribution between 0 and 1 \n"
    "for comparison with Pr to decide whether to activate the synapse or not\n"
    "ENDCOMMENT\n"
    "   \n"
    "VERBATIM\n"
    "\n"
    "#include<stdlib.h>\n"
    "#include<stdio.h>\n"
    "#include<math.h>\n"
    "\n"
    "double nrn_random_pick(void* r);\n"
    "void* nrn_random_arg(int argpos);\n"
    "\n"
    "ENDVERBATIM\n"
    "  \n"
    "\n"
    "ASSIGNED {\n"
    "\n"
    "        v (mV)\n"
    "        i (nA)\n"
    "	i_AMPA (nA)\n"
    "	i_NMDA (nA)\n"
    "        g_AMPA (uS)\n"
    "	g_NMDA (uS)\n"
    "        factor_AMPA\n"
    "	factor_NMDA\n"
    "	rng\n"
    "}\n"
    "\n"
    "STATE {\n"
    "\n"
    "        A_AMPA       : AMPA state variable to construct the dual-exponential profile - decays with conductance tau_r_AMPA\n"
    "        B_AMPA       : AMPA state variable to construct the dual-exponential profile - decays with conductance tau_d_AMPA\n"
    "	A_NMDA       : NMDA state variable to construct the dual-exponential profile - decays with conductance tau_r_NMDA\n"
    "        B_NMDA       : NMDA state variable to construct the dual-exponential profile - decays with conductance tau_d_NMDA\n"
    "}\n"
    "\n"
    "INITIAL{\n"
    "\n"
    "        LOCAL tp_AMPA, tp_NMDA\n"
    "        \n"
    "	A_AMPA = 0\n"
    "        B_AMPA = 0\n"
    "	\n"
    "	A_NMDA = 0\n"
    "	B_NMDA = 0\n"
    "        \n"
    "	tp_AMPA = (tau_r_AMPA*tau_d_AMPA)/(tau_d_AMPA-tau_r_AMPA)*log(tau_d_AMPA/tau_r_AMPA) :time to peak of the conductance\n"
    "	tp_NMDA = (tau_r_NMDA*tau_d_NMDA)/(tau_d_NMDA-tau_r_NMDA)*log(tau_d_NMDA/tau_r_NMDA) :time to peak of the conductance\n"
    "        \n"
    "	factor_AMPA = -exp(-tp_AMPA/tau_r_AMPA)+exp(-tp_AMPA/tau_d_AMPA) :AMPA Normalization factor - so that when t = tp_AMPA, gsyn = gpeak\n"
    "        factor_AMPA = 1/factor_AMPA\n"
    "	\n"
    "	factor_NMDA = -exp(-tp_NMDA/tau_r_NMDA)+exp(-tp_NMDA/tau_d_NMDA) :NMDA Normalization factor - so that when t = tp_NMDA, gsyn = gpeak\n"
    "        factor_NMDA = 1/factor_NMDA\n"
    "   \n"
    "}\n"
    "\n"
    "BREAKPOINT {\n"
    "\n"
    "        SOLVE state METHOD cnexp\n"
    "	mggate = 1 / (1 + exp(0.062 (/mV) * -(v)) * (mg / 3.57 (mM))) :mggate kinetics - Jahr & Stevens 1990\n"
    "        g_AMPA = gmax*(B_AMPA-A_AMPA) :compute time varying conductance as the difference of state variables B_AMPA and A_AMPA\n"
    "	g_NMDA = gmax*(B_NMDA-A_NMDA) * mggate :compute time varying conductance as the difference of state variables B_NMDA and A_NMDA and mggate kinetics\n"
    "        i_AMPA = g_AMPA*(v-e) :compute the AMPA driving force based on the time varying conductance, membrane potential, and AMPA reversal\n"
    "	i_NMDA = g_NMDA*(v-e) :compute the NMDA driving force based on the time varying conductance, membrane potential, and NMDA reversal\n"
    "	i = i_AMPA + i_NMDA\n"
    "}\n"
    "\n"
    "DERIVATIVE state{\n"
    "\n"
    "        A_AMPA' = -A_AMPA/tau_r_AMPA\n"
    "        B_AMPA' = -B_AMPA/tau_d_AMPA\n"
    "	A_NMDA' = -A_NMDA/tau_r_NMDA\n"
    "        B_NMDA' = -B_NMDA/tau_d_NMDA\n"
    "}\n"
    "\n"
    "\n"
    "NET_RECEIVE (weight, Pv, Pv_tmp, Pr, u, tsyn (ms)){\n"
    "	\n"
    "	:weight_AMPA = weight\n"
    "	:weight_NMDA = weight*weight_factor_NMDA\n"
    "	:printf(\"NMDA weight = %g\\n\", weight_NMDA)\n"
    "\n"
    "        INITIAL{\n"
    "                Pv=1\n"
    "                u=u0\n"
    "                tsyn=t\n"
    "            }\n"
    "\n"
    "        : calc u at event-\n"
    "        if (Fac > 0) {\n"
    "                u = u*exp(-(t - tsyn)/Fac) :update facilitation variable if Fac>0 Eq. 2 in Fuhrmann et al.\n"
    "           } else {\n"
    "                  u = Use  \n"
    "           } \n"
    "           if(Fac > 0){\n"
    "                  u = u + Use*(1-u) :update facilitation variable if Fac>0 Eq. 2 in Fuhrmann et al.\n"
    "           }    \n"
    "\n"
    "        \n"
    "            Pv_tmp  = 1 - (1-Pv) * exp(-(t-tsyn)/Dep) :Probability Pv for a vesicle to be available for release, analogous to the pool of synaptic\n"
    "                                                      :resources available for release in the deterministic model. Eq. 3 in Fuhrmann et al.\n"
    "            Pr  = u * Pv_tmp                          :Pr is calculated as Pv * u (running value of Use)\n"
    "            Pv_tmp  = Pv_tmp - u * Pv_tmp             :update Pv as per Eq. 3 in Fuhrmann et al.\n"
    "            :printf(\"Pv = %g\\n\", Pv)\n"
    "            :printf(\"Pr = %g\\n\", Pr)\n"
    "                \n"
    "		   if (erand() < Pr){\n"
    "		    tsyn = t\n"
    "	            Pv = Pv_tmp\n"
    "                    A_AMPA = A_AMPA + weight*factor_AMPA\n"
    "                    B_AMPA = B_AMPA + weight*factor_AMPA\n"
    "		    A_NMDA = A_NMDA + weight*weight_factor_NMDA*factor_NMDA\n"
    "                    B_NMDA = B_NMDA + weight*weight_factor_NMDA*factor_NMDA\n"
    "\n"
    "                }\n"
    "}\n"
    "\n"
    "PROCEDURE setRNG() {\n"
    "VERBATIM\n"
    "    {\n"
    "        /**\n"
    "         * This function takes a NEURON Random object declared in hoc and makes it usable by this mod file.\n"
    "         * Note that this method is taken from Brett paper as used by netstim.hoc and netstim.mod\n"
    "         * which points out that the Random must be in negexp(1) mode\n"
    "         */\n"
    "        void** pv = (void**)(&_p_rng);\n"
    "        if( ifarg(1)) {\n"
    "            *pv = nrn_random_arg(1);\n"
    "        } else {\n"
    "            *pv = (void*)0;\n"
    "        }\n"
    "    }\n"
    "ENDVERBATIM\n"
    "}\n"
    "\n"
    "FUNCTION erand() {\n"
    "VERBATIM\n"
    "	    //FILE *fi;\n"
    "        double value;\n"
    "        if (_p_rng) {\n"
    "                /*\n"
    "                :Supports separate independent but reproducible streams for\n"
    "                : each instance. However, the corresponding hoc Random\n"
    "                : distribution MUST be set to Random.negexp(1)\n"
    "                */\n"
    "                value = nrn_random_pick(_p_rng);\n"
    "		        //fi = fopen(\"RandomStreamMCellRan4.txt\", \"w\");\n"
    "                //fprintf(fi,\"random stream for this simulation = %lf\\n\",value);\n"
    "                //printf(\"random stream for this simulation = %lf\\n\",value);\n"
    "                return value;\n"
    "        }else{\n"
    "ENDVERBATIM\n"
    "                : the old standby. Cannot use if reproducible parallel sim\n"
    "                : independent of nhost or which host this instance is on\n"
    "                : is desired, since each instance on this cpu draws from\n"
    "                : the same stream\n"
    "                erand = exprand(1)\n"
    "VERBATIM\n"
    "        }\n"
    "ENDVERBATIM\n"
    "        :erand = value :This line must have been a mistake in Hay et al.'s code, it would basically set the return value to a non-initialized double value.\n"
    "                       :The reason it sometimes works could be that the memory allocated for the non-initialized happened to contain the random value\n"
    "                       :previously generated (or if _p_rng is always a null pointer). However, here we commented this line out.\n"
    "}\n"
    "\n"
    "\n"
    "\n"
    "\n"
    "\n"
    "\n"
    ;
  #endif
  