Acadamia niche, limited customers - worth a startup?
I've been tossing around a startup idea designed to serve the biomedical acadamia niche.  I'm a molecular neurobiologist with a comp-sci background, so I'm familiar with the various difficulties the biomedical acadamic community faces.  I think my idea is a tractable problem that hasn't been addressed by others in a sufficient manner (yet).<p>My concern, however, is that the market is necessarily limited.  The academic biomedical community is not huge and has modest wallets.  I imagine the product would be licensed to institutes and universities as a site-wide service, rather than individual labs.<p>My question:  Should one jump into a startup knowing that the niche is small and has a ceiling on potential customers?  Customers who are at the mercy of limited budgets?