messages: 'dès lors que le système de gestion des risques est modifié, notamment en cas de réception de nouvelles informations pouvant entraîner un changement significatif du profil bénéfice/risque, ou lorsqu’une'
  
  
  
  Turn this sentence from French to English for me
messages: user
messages: 'Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of'
messages: assistant