Sure! C, C++, and C# are related but distinct, and they differ in many ways. 

C is the oldest and most widely-used of these three languages. It's a very low-level language that was invented in 1972 to replace assembly in complex projects. In general, C code is just as efficient as assembly code, and may beat all but the most carefully optimized assembly due to compiler optimizations. However, as an old and low-level language, C lacks many of the features and conveniences of modern languages. C is used in low-level applications, such as drivers, operating systems, embedded systems, and more. 

C++, published in 1985, is another highly popular language. It was invented as an enhancement to C, especially to add object-orientation, without sacrificing efficiency or capability. The C++ language also features a powerful standard library to aid development, and is generally less difficult to write and less error-prone than C. Like C, C++ is used in high-efficiency applications like operating systems and embedded devices, but has also found use in frontend applications like web browsers and games. 

C# is the most modern of the three languages, invented by Microsoft in 2002. C# adds garbage collection and other capabilities to C. C# compiles to bytecode, which is then compiled to machine code on the fly at runtime, whereas C and C++ compile directly to machine code. C# is often used in server-side software, and is notably used by the Unity game engine. 

Overall, these languages differ in many different ways despite their similar names. Choosing which one to use for a particular project will depend heavily on your use case.
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