Sure, here are some common signs or indicators that might suggest it's time to change the liquid in a custom liquid cooling system of a water-cooled PC:

- Discoloration of the liquid. If the liquid in your cooling system starts to turn cloudy or discolored, it's a sign that it's time for a change. This is because the liquid can break down over time and become contaminated with particles or other substances.
- Rust or corrosion. If you see any rust or corrosion on the components in your cooling system, it's a sign that the liquid is no longer doing its job of protecting them. This can lead to leaks and other problems, so it's important to change the liquid as soon as possible.
- High temperatures. If you're noticing that your CPU or GPU temperatures are starting to get too high, even when you're not running demanding applications, it could be a sign that the liquid in your cooling system is not circulating properly. This can be caused by a number of things, including a leak, a blockage, or simply old, dirty liquid.
- Noise. If you start to hear strange noises coming from your cooling system, such as gurgling or bubbling, it could be a sign that the liquid is not circulating properly. This can also be caused by a leak or a blockage.
- Odor. If you start to notice a strange odor coming from your cooling system, such as a sweet or sour smell, it's a sign that the liquid is contaminated. This can be caused by a number of things, including bacteria, algae, or mold.
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