Fixing any "foreign" apparatus to the body always risks infection or rejection by the body. Pacemakers can remain in place for many years because they provide only an electrical stimulus to the heart using a fine probe, to regulate its rate, rather than outright replacing it.
If the "foreign" apparatus replaces a major organ (such as the heart) even small complications, such as poor seals, or inflammation (extremely common with procedures such as shunts or stomas) can quickly become life-threatening or fatal.
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