As with all medications, it's essential to work closely with a veterinarian to ensure it's used safely and effectively.

Here's a brief summary:
**What is benazepril?**
Benazepril is an angiotensin-converting enzyme (ACE) inhibitor. It's commonly used in both human and veterinary medicine to treat conditions like high blood pressure (hypertension).
**How does it work?**
ACE inhibitors like benazepril block the conversion of angiotensin I to angiotensin II. Angiotensin II causes blood vessels to constrict and promotes the release of aldosterone, which can lead to fluid retention and further increase blood pressure.
By blocking this conversion, benazepril helps dilate blood vessels and reduce blood pressure. This can reduce the workload on the heart and decrease protein loss through the kidneys, which are both beneficial effects for cats with chronic kidney disease (CKD).
**Benefits in cats with kidney disease:**
Reduces proteinuria: Chronic protein loss in the urine (proteinuria) is a common problem in cats with CKD. Benazepril can help reduce proteinuria, which can slow the progression of kidney disease.
Lowers blood pressure: Hypertension is a frequent complication of CKD in cats. Maintaining a normal blood pressure can prevent further damage to the kidneys and other organs.
Possible protective effects on the kidneys due to improved blood flow and reduced intra-glomerular pressure.
**Dosage and Administration:**
The dosage and frequency of administration depend on the specific needs of the individual cat and should be determined by a veterinarian.
It's generally given orally, either in tablet form or as a liquid.
**Side effects:**
Generally well-tolerated in cats.
Potential side effects can include lethargy, decreased appetite, vomiting, diarrhea, and a worsening of kidney values.
Regular monitoring by a veterinarian is essential to ensure the drug is having the desired effect and not causing any adverse reactions.
**Contraindications and interactions:**
Benazepril should be used with caution in cats with certain medical conditions or those on specific medications. Always consult with a veterinarian before starting or changing any medication.
**Monitoring:**
Regular blood pressure checks and blood tests to monitor kidney values and electrolytes are crucial when a cat is on benazepril or any other medication for CKD.
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