Sure, here's a simple melody that switches from pure E major to E major with a dissonant F:

``` 
X:1
T: E Major Melody
M:4/4
L:1/4
K:E
|: E2 G2 A2 | B2 B2 B2 | E2 G2 A2 | F2 F2 F2 |
E2 G2 A2 | B2 B2 B2 | E2 G2 A2 | F2 F2 F2 :|
``` 
In the first three measures, the melody follows a simple arpeggio of the E major chord, with the notes E, G#, and B played in sequence. In the fourth measure, the F# is replaced with F, which creates a dissonant effect.
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