No, both the Flexbox and margin techniques should work well on both desktop and mobile browsers, provided that the browsers support the CSS specifications for these techniques.

It's important to note that some older mobile browsers may not support the latest CSS specifications, so you may want to test your site on a variety of browsers and devices to ensure that it looks and behaves as expected. Additionally, some mobile devices have different screen dimensions, so it may be necessary to adjust your CSS to account for these differences.

In general, both the Flexbox and margin techniques are widely supported and should work well on most modern browsers, both on desktop and mobile devices.
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