one way to approach this question is to estimate the number of possible brain states. Assuming an average of 86 billion neurons, each with two possible states (firing or not firing), the total number of possible brain states would be 2 to the power of 86 billion, which is an astronomically large number. In fact, it's estimated to be around 10 to the power of 25,705,292.

Assuming exponential growth of the human population, with a current population of around 7.9 billion and a conservative growth rate of 1% per year, it would take approximately 7,000 years for the human population to reach 10 to the power of 100 (a number often used to represent the total number of particles in the observable universe).

If we assume that advanced technology allows for every possible experience to be had, it's possible that new experiences could continue to generate new brain states, potentially extending the timeline even further.

However, it's important to note that the concept of a "truly original thought" is difficult to define and quantify. Even if the number of possible brain states were to be exhausted, it's possible that new combinations of existing ideas and experiences could continue to generate novel insights and perspectives. Additionally, creativity and innovation are influenced by a complex interplay of genetic, environmental, and cultural factors, which makes it challenging to predict the limits of human creativity.
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