Sure, I'd be glad to elaborate.

**Osteoarthritis (OA)**:
This is the most common form of arthritis and is often referred to as "wear and tear" arthritis as it typically occurs due to the gradual wearing away of cartilage in the joints. Symptoms usually develop slowly and worsen over time, and can include:

- Joint pain during or after movement.
- Stiffness upon waking up or after being inactive.
- Loss of flexibility in the joint.
- Tenderness when the joint is pressed lightly.
- A grating sensation during joint use.

OA generally appears in middle age and progresses with age, It's noteworthy that osteoarthritis can be asymmetric, meaning it can affect one side (e.g., a knee, hip, or hand) more than the other.

**Rheumatoid arthritis (RA)**: 
In contrast, this is an autoimmune disease where the body's immune system mistakenly attacks its own tissues, affecting the lining of the joints and resulting in painful swelling that can lead to joint deformity. 

Common RA symptoms include:

- Tender, warm, swollen joints.
- Morning stiffness that can last for hours.
- Rheumatoid nodules — firm bumps of tissue under the skin on your arms.
- Fatigue, fever, and weight loss.

RA often affects smaller joints first such as those in the fingers and toes before it progresses to larger joints like knees and elbows. Unlike OA, RA usually affects joints symmetrically.

So while both conditions can cause joint pain and stiffness, they are fundamentally different in their origin and progression. Diagnosing between them requires a careful review of symptoms, medical history, and often specific confirmation tests such as blood tests or imaging.
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