By choosing Django, you may miss out on some of the flexibility and simplicity that Flask offers, as Django comes with a lot of built-in features and can sometimes feel monolithic in comparison. However, the trade-off is that Django provides a lot of out-of-the-box functionality that can save you time and effort in building a website. Additionally, Django is well-suited for large, complex projects and can scale well as your site grows in popularity.

On the other hand, by choosing Flask, you may miss out on some of the robust, advanced features that Django provides, but you will gain more control over the specifics of your application. Flask is lightweight and flexible, making it a good choice for small to medium-sized projects, but it may require more effort to add additional functionality as your project grows.

In summary, it depends on the size, complexity and requirements of your project. If your site is expected to handle large amounts of traffic and requires a lot of advanced functionality, Django might be a better choice. On the other hand, if you are building a simple website or prototyping, Flask might be a good place to start.
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