Here's a `docker-compose.yml` file to set up N8N, Nginx Proxy Manager, Supabase, and Appsmith. This example assumes that you have your own domain and an existing network called "webproxy" where Nginx Proxy Manager connects.

```yaml
version: '3.8'

services:
  n8n:
    image: n8nio/n8n
    container_name: n8n
    environment:
      - N8N_BASIC_AUTH_ACTIVE=true
      - N8N_BASIC_AUTH_USER=your-username
      - N8N_BASIC_AUTH_PASSWORD=your-password
      - N8N_HOST=n8n.example.com
      - N8N_PORT=5678
      - N8N_PROTOCOL=https
      - NODE_ENV=production
    labels:
      - "traefik.enable=true"
      - "traefik.http.routers.n8n.rule=Host(`n8n.example.com`)"
      - "traefik.http.routers.n8n.entrypoints=websecure"
      - "traefik.http.routers.n8n.tls.certresolver=le"
    volumes:
      - ./n8n/data:/root/.n8n
    networks:
      - webproxy

  supabase:
    image: supabase/postgres:0.14.0
    container_name: supabase
    environment:
      POSTGRES_DB: your_database_name
      POSTGRES_USER: your_username
      POSTGRES_PASSWORD: your_password
    volumes:
      - ./supabase/data:/var/lib/postgresql/data
    networks:
      - default

  appsmith:
    image: appsmith/appsmith:latest
    container_name: appsmith
    environment:
      APPSMITH_MONGODB_URI: mongodb://mongodb:27017/appsmith
      APPSMITH_REDIS_URL: redis://redis:6379
      APPSMITH_ENCRYPTION_PASSWORD: your_encryption_password
      APPSMITH_ENCRYPTION_SALT: your_encryption_salt
    labels:
      - "traefik.enable=true"
      - "traefik.http.routers.appsmith.rule=Host(`appsmith.example.com`)"
      - "traefik.http.routers.appsmith.entrypoints=websecure"
      - "traefik.http.routers.appsmith.tls.certresolver=le"
    depends_on:
      - db
      - redis
    networks:
      - webproxy

  db:
    image: mongo:4.4
    container_name: appsmith-db
    volumes:
      - ./appsmith/data/db:/data/db
    networks:
      - default

  redis:
    image: redis:6-alpine
    container_name: appsmith-redis
    volumes:
      - ./appsmith/data/redis:/data
    networks:
      - default

networks:
  webproxy:
    external: true
  default:
    driver: bridge
```

Remember to replace the placeholder values with your own settings, such as domain names and credentials. Please note that the Nginx Proxy Manager service isn't included in this file, as it's expected to be set up separately. The services in this file are connected to the webproxy network, which should be the same network that the Nginx Proxy Manager is using.

You might need to adapt the Traefik labels if you're using a different reverse proxy solution or if your configuration differs from the example provided. Also, make sure to create the required volumes for data persistence on your host before starting the containers.
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