Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced  = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H+ + H2O + oxidized . (5Z,8Z,11Z,14Z)-icosatetraenoic acid is also known as arachidonic acid is also and 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate as 20-HETE.
arachidonic acid hydroxylase activity