Catalyzes the multi-step reaction: L-tryptophan + 2 O2 + 2 reduced  = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H+ + 3 H2O + 2 oxidized .
L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)