<|im_start|>system
You are a helpful AI assistant.<|im_end|>
<|im_start|>user
What are the most respected and/or recent studies about coffee consumption and whether it's healthy? Please give me top 5 to 10, with a quick summary and a link<|im_end|>
<|im_start|>assistant
I can provide you with a list of some influential studies on coffee consumption and its potential health effects. Here are ten notable studies with brief summaries and links to further explore:

"Association of Coffee Consumption with Total and Cause-Specific Mortality" (2017):
This study observed a lower risk of death among coffee drinkers, particularly due to cardiovascular disease and neurologic diseases.
Link: https://www.ncbi.nlm.nih.gov/pubmed/28737627

"Coffee Consumption and Health: Umbrella Review of Meta-analyses of Multiple Health Outcomes" (2017):
This review examined a range of health outcomes associated with coffee consumption, including cardiovascular disease, cancer, and liver disease, and found mostly beneficial or neutral effects.
Link: https://www.ncbi.nlm.nih.gov/pubmed/29053897

"Coffee, Caffeine, and Risk of Depression Among Women" (2011):
The study suggested that higher coffee consumption might be associated with a lower risk of depression in women.
Link: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1105943

"Association of Coffee Drinking with Mortality by Genetic Variation in Caffeine Metabolism" (2018):
This study indicated that coffee consumption may be associated with a lower risk of death in individuals with specific genetic variations related to caffeine metabolism.
Link: https://www.ncbi.nlm.nih.gov/pubmed/29972778

"Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review" (2013):
The review found an inverse association between coffee consumption and the risk of developing type 2 diabetes.
Link: https://www.ncbi.nlm.nih.gov/pubmed/23193023

"Coffee Consumption and Risk of Gastric Cancer: A Large Updated Meta-Analysis of Prospective Studies" (2019):
This meta-analysis suggested that higher coffee intake may be associated with a reduced risk of gastric cancer.
Link: https://www.ncbi.nlm.nih.gov/pubmed/30468035

"Coffee Consumption and the Risk of Colorectal Cancer" (2016):
The study found a potential inverse association between coffee consumption and the risk of colorectal cancer.
Link: https://pubmed.ncbi.nlm.nih.gov/27698025/

"Association of Coffee Consumption with Overall and Cause-Specific Mortality in a Large US Prospective Cohort Study" (2015):
This large cohort study indicated an inverse association between coffee consumption and mortality, particularly for heart disease, respiratory disease, stroke, injuries, accidents, and diabetes.
Link: https://www.ncbi.nlm.nih.gov/pubmed/26109579

"Coffee and Caffeine Consumption and Depression: A Meta-analysis of Observational Studies" (2016):
The meta-analysis suggested that coffee and caffeine consumption may be associated with a lower risk of depression.
Link: https://www.ncbi.nlm.nih.gov/pubmed/26757040

"Coffee Consumption and Risk of Nonmelanoma Skin Cancer: A Dose-Response Meta-analysis" (2021):
This meta-analysis found a potential inverse relationship between coffee consumption and the risk of nonmelanoma skin cancer.
Link: https://www.ncbi.nlm.nih.gov/pubmed/33338434<|im_end|>
<|im_start|>user
Sorry, but that's not what I wanted. Please try to give a list of 5 to 10 papers regarding coffee consumption.<|im_end|>
<|im_start|>assistant
Here is a rundown of some important studies on the effects of coffee consumption up to my last update.

1. **Association of Coffee Drinking with Mortality by Genetic Variation in Caffeine Metabolism** (2018)
    - This study from JAMA Internal Medicine showed a potential benefit from coffee consumption, with an association between drinking coffee and a lower risk of death, regardless of whether individuals metabolize caffeine slowly or quickly.
    - [Link to the study](https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2686145)

2. **Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes** (2017)
   - Published in The BMJ, this review of over 200 meta-analyses indicated that coffee consumption was more often associated with benefit than harm for a range of health outcomes across exposures including high versus low, any versus none, and one extra cup a day.
   - [Link to the study](https://www.bmj.com/content/359/bmj.j5024)

3. **Coffee Consumption and Coronary Artery Calcium Score: Cross‐Sectional Results of ELSA‐Brasil (Brazilian Longitudinal Study of Adult Health)** (2015)
   - The study suggested that moderate coffee consumption (about three cups per day) might be inversely associated with coronary artery calcium deposition, which is considered a marker of future heart disease risk.
   - [Link to the study](https://pubmed.ncbi.nlm.nih.gov/29574458/)

4. **Coffee Consumption and Health: A Review of Recent Human Research** (2006)
   - Published in Critical Reviews in Food Science and Nutrition, the review concludes that the overall benefits of coffee consumption appear to outweigh the risks.
   - [Link to the study](https://www.tandfonline.com/doi/abs/10.1080/10408390500400009)

5. **Coffee, Caffeine, and Health Outcomes: An Umbrella Review** (2017)
   - This review of 112 unique health outcomes related to coffee consumption, published in Annual Review of Nutrition, suggested that coffee consumption is associated with decreased all-cause mortality and a reduced risk of several chronic diseases.
   - [Link to the study](https://pubmed.ncbi.nlm.nih.gov/28826374/)

6. **Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases** (2019)
   - Published in The American Journal of Clinical Nutrition, the study suggests a moderate amount of coffee is linked to a lower risk of heart disease.
   - [Link to the study](https://academic.oup.com/ajcn/article/109/3/509/5369955)

7. **Coffee consumption and risk of type 2 diabetes mellitus: an 11-year prospective study of 28 812 postmenopausal women** (2006)
   - This research published in the Archives of Internal Medicine suggested that long-term (over 10 years) coffee consumption is associated with a statistically significantly lower risk for type 2 diabetes.
   - [Link to the study](https://pubmed.ncbi.nlm.nih.gov/16801515/)

8. **Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies** (2014)
   - Published in Circulation, this study found that moderate coffee consumption was inversely significantly associated with cardiovascular disease risk, with the lowest CVD risk at 3 to 5 cups per day, and heavy coffee consumption was not associated with elevated CVD risk.
   - [Link to the study](https://www.ahajournals.org/doi/full/10.1161/circulationaha.113.005925)

9. **Coffee Consumption and Total Mortality: A Meta-Analysis of Twenty Prospective Cohort Studies** (2014)
   - This study suggested a non-linear association between coffee consumption and total mortality, with the largest risk reduction observed at 3 to 4 cups/day.
   - [Link to the study](https://pubmed.ncbi.nlm.nih.gov/24279995/)

10. **Association of Coffee Consumption With Total and Cause-Specific Mortality in 3 Large Prospective Cohorts** (2015)
   - This study concluded that moderate consumption of coffee, up to 5 cups per day, was associated with a lower risk of death from cardiovascular disease, neurological diseases, type 2 diabetes, and suicide.
   - [Link to the study](https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.115.017341)

Remember to always consult a healthcare provider before making any major changes to your diet or lifestyle. The effects of coffee can vary based on many individual factors, including your overall health, genetic makeup, and the amount and type of coffee consumed.<|im_end|>