Earl Reece Stadtman
{{Infobox scientist
| name = Earl Stadtman
| image=Thressa & Earl Stadtman (30850367433) (cropped).jpg| caption= Earl Reece and Thressa Stadtman, 2004
| birth_name        = Earl Reece Stadtman
| birth_date        = 
| birth_place       = Carrizozo, New Mexico, USA
| death_date        = 
| death_place       = Derwood, Maryland, USA
| fields            = Biochemistry
| workplaces        = Georgetown University, Washington, DC; University of Maryland, College Park, Maryland; Johns Hopkins University; National Heart Institute, Bethesda, Maryland; many visiting appointments
| patrons           = 
| education         = University of California, Berkeley (Ph.D. 1949)
| thesis_title      = 'Mechanisms of Fatty Acid Synthesis by Clostridium kluyveri
| academic_advisors = Horace Barker
| doctoral_students = 
| notable_students  = 
| known_for         = Fatty aid biosynthesis, glutamine dehydrogenase, cycles of interconvertible enzymes
| influences        = 
| awards            = Pfizer Award in Enzyme Chemistry, American Academy of Arts and Sciences, National Academy of Sciences, National Medal of Science, many others
| spouse            = Thressa Campbell Stadtman
| children          = None
| parents           =
| father            =
| mother            =
}}
Earl Reece Stadtman NAS (November 15, 1919 – January 7, 2008) was an American biochemist,The Stadtman Way: A Tale of two biochemists at NIH
notable for his research on enzymes
and anaerobic bacteria.

 Career 
Stadtman started his career as a research assistant in the Division of Plant Nutrition of the University of California. Subsequently he was an Atomic Energy Commission Fellow with Fritz Lipmann in the Massachusetts General Hospital, but after 1960 he worked at the National Heart Institute,
where he became chief of the Laboratory of Biochemistry. In addition, he spent sabbatical periods at the Max Planck Institute in Munich and the Pasteur Institute in Paris.

 Personal life 
In 1944 Earl Stadtman married Thressa Campbell, also a distinguished scientist, the discoverer of  selenocysteine. They had no children during their marriage of more than sixty years.

 Research 

Stadtman's research covered a wide field. Early in his career he worked with Horace Barker on bacterial fatty-acid synthesis, with a series of four papers. In the same period he collaborated with Fritz Lipmann on the function of coenzyme A. Later his work took on a more enzymological character, with investigation of, for example, aldehyde dehydrogenase, aspartate kinase, work carried out during a period in the laboratory of Georges Cohen in France and, most notably, glutamine synthetase, an enzyme that will always be associated with his name.

From the 1970s onwards Stadtman published many papers with P. Boon Chock on the capacity of cycles of interconvertible enzymes, based especially on his results with glutamine synthetase, to generate very high sensitivity to effectors.

 Editorial work 

Stadtman was active as an editor of numerous prominent journals, including the Journal of Biological Chemistry, 1960–1965, Archives of Biochemistry and Biophysics, 1960–1969; Annual Review of Biochemistry, 1972–2000; Biochemistry, 1969–1976; Proceedings of the National Academy of Sciences, 1974–1981; Trends in Biochemical Sciences,  1975–1978.

He was (with Bernard Horecker) founding editor of Current Topics in Cellular Regulation,'' a major series in the subject, and continued in the role up to volume 23 (1984).

Awards and honours 

 1953: Pfizer Award in Enzyme Chemistry
 1966: Medallion of the University of Pisa, Italy
 1969: elected to the American Academy of Arts and Sciences
 1969: elected to the National Academy of Sciences
 1970: awarded Selman A. Waksman Award in Microbiology
 1972: Medallion of the University of Camerino, Italy
 1979: National Medal of Science
 1983: President, American Society of Biological Chemists
 1983: ASBC-Merck Award
 1987: Honorary Doctor of Science, University of Michigan
 1988: Honorary Ph.D., Weizmann Institute of Science, Israel
 1991: Welch Award in Chemistry
 1999: Honorary Ph.D., University of Pennsylvania

References

External links

1919 births
2008 deaths
University of California, Berkeley alumni
Members of the United States National Academy of Sciences
National Medal of Science laureates
People from Lincoln County, New Mexico
Scientists from New Mexico
20th-century American biochemists
National Institutes of Health people