Dr. Tom Colletti
Objective: The purpose of this article is to review evidence-based literature on the reduction of type 2 diabetes (T2DM) in pre-diabetes (preDM) through lifestyle modifications and the prevention of microvascular and macrovascular complications.
Methods: Randomized controlled trials were reviewed on the current recommendations for diet, physical activity, and weight reduction in preDM to prevent T2DM and its complications. The review was conducted using a database search on evidence-based literature to include PubMed, British Medical Journal, and Google Scholar. The articles selected are peer-reviewed, between 2017-2019, and several focused on lifestyle modifications versus medications. A work librarian was consulted on article organization.
Results: Studies show that the onset of diabetes can be reduced with weight loss through lifestyle modifications. The studies also confirm lifestyle modifications are superior to metformin. There is a connection between microvascular and macrovascular disease in pre-diabetes.
Conclusion: All studies were successful in demonstrating that lifestyle modifications are essential in managing pre-diabetes. Weight loss is the key, and more specifically at ≥5%, in the prevention of T2DM. The lifestyle modification programs discussed are realistic and can be coordinated by clinicians in primary care. Microvascular and macrovascular diseases were often discovered at the diagnosis of type 2 diabetes. The link between pre-diabetes and cardiovascular disease (CVD) has been established. Clinicians should be aware of the outcomes for their patients.
Palmer J. The Efficacy of Lifestyle Modifications in Pre-diabetes to Prevent Type 2 Diabetes. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2021; 3(3).
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Lengo la makala hii ni kukagua fasihi ya msingi ya ushahidi juu ya kupunguza ugonjwa wa kisukari wa aina ya 2 (T2DM) katika kabla ya ugonjwa wa kisukari (pre-DM) kupitia mabadiliko ya mtindo wa maisha na kuzuia matatizo ya microvascular na macrovascular. Utafiti wa randomized uliopimwa ulionyesha kuwa viwango vya juu vya lishe, mazoezi ya mwili, na kupunguza uzito katika watu walio na ugonjwa wa pre-DM vinaweza kuzuia ugonjwa wa aina ya 2 na matatizo yake. Uchunguzi huo ulifanywa kwa kutumia utafutaji wa hifadhidata kwenye fasihi ya msingi wa ushahidi kujumuisha PubMed, Jarida la Matibabu la Uingereza, na Google Scholar. Makala zilizochaguliwa ni peer-reviewed, kati ya 2017-2019, na kadhaa zililenga mabadiliko ya mtindo wa maisha dhidi ya dawa. Mkurugenzi wa maktaba ya kazi aliulizwa juu ya utaratibu wa makala. Matokeo: Uchunguzi unaonyesha kwamba kuambukizwa kisukari kunaweza kupunguzwa kwa kupunguza uzito kwa kufanya marekebisho katika mtindo wa maisha. Uchunguzi huo pia unathibitisha kwamba marekebisho ya mtindo wa maisha ni bora kuliko metformin. Kuna uhusiano kati ya ugonjwa wa mishipa midogo ya damu na ugonjwa wa mishipa mikubwa ya damu katika hali ya kabla ya kisukari. Matokeo: Uchunguzi wote ulifanikiwa kuonyesha kwamba marekebisho ya mtindo wa maisha ni muhimu katika kusimamia kabla ya kisukari. Kupunguza uzito ni muhimu, na hasa kwa ≥5%, katika kuzuia T2DM. Programu za kurekebisha mtindo wa maisha zinazozungumziwa ni za kweli na zinaweza kuratibiwa na madaktari katika huduma ya msingi. Ugonjwa wa microvascular na macrovascular mara nyingi uligunduliwa wakati wa utambuzi wa ugonjwa wa kisukari wa aina ya 2. Uhusiano kati ya ugonjwa wa kisukari na ugonjwa wa moyo na mishipa ya damu (CVD) umethibitishwa. Madaktari wanapaswa kujua matokeo kwa wagonjwa wao. J. Palmer Ufanisi wa Marekebisho ya Mtindo wa Maisha katika Prediabetes Kuzuia Aina ya 2 ya Kisukari Chuo Kikuu cha Lynchburg DMSC Doctoral Project Assignment Repository. 2021; 3 (3) Inapatikana wakati wa kupata kupitia anwani ya IP ya chuo au kuingia na anwani ya barua pepe ya Chuo Kikuu cha Lynchburg. Watumiaji wa nje ya chuo pia wanaweza kutumia 'Off-campus Download' kifungo juu kwa ajili ya upatikanaji.