The history of coating goes back to the early 1950s when the first pills were coated with sugar to conceal the unpleasant taste. More and more attention was paid to processes that were not only faster and more efficient, but also had a decisive influence on the release of active ingredients. Conventional processes based on water and organic solvents were developed for this purpose. These processes are the most widely used today and are constantly being further developed. A new field is trying to apply the coating substances directly in dry form, without first dissolving them in water or organic solvents. These solvent-free processes could displace conventional methods in the future, as they are efficient, resource-saving, quick to implement and energy-saving.
Coating is a broad field even in pharmaceuticals, as the question arises: when, how, for how long, and where should the active ingredient be released? Even the released amount in each case can be controlled. All parts of a capsule or tablet can be coated: if, for example, the drug itself, the granules or the resulting capsule/tablet are coated differently, the release of the active ingredient can be controlled variably.
The coating process is used for mainly three reasons: Improvement of compliance/drug safety, protective function and improvement of bio pharmacy.
Improving compliance and drug safety is a main reason why tablets are coated: The applied coating makes the tablet look nicer, hides bad taste and facilitates identification (most active ingredients and excipients are white). The patient or customer can not only better identify his product, but also swallow it more easily: due to selected substances, there is no absorption of water from the oral mucosa (into the tablet). The result is pleasant swallowing without possible sticking to the inside of the mouth-esophagus.
The coating also protects the active ingredient from atmospheric oxygen, moisture, light and gastric acid. It also prevents mechanical abrasion, for example during transport: the resulting dust can be harmful to health if inhaled. The coating is not only a protection for the patient and from the active ingredient, but also a protection from other active ingredients: if several active ingredients are pressed into one tablet, chemical reactions can occur among the active ingredients. A protective film can prevent this and increase patient compliance by eliminating the need to take multiple tablets.
The biopharmaceutical setting is also advantageous: the applied coating not only protects the gastric mucosa from active ingredients, but also safeguards the drug against aggressive gastric acid. If the right coating materials are chosen, the drug delivery can be specifically modified or controlled (e.g. enteric-coated, small intestine-soluble coating).
In pharmacy, coating is one of the coated solid dosage forms with the main forms being dragées and conventional dragées. Dragées are further subdivided into conventional dragées and quick dragées.
In conventional dragées, the actual core is coated with sugar so that the resulting shape & volume are completely different from the original core. This also makes desired embossing impossible, as the sugar layer is too thick. In order to be able to apply these quantities of sugar, the core must have a certain web height and curvature. In this case, the sugar solution is applied in several layers of different composition (difference to fast dragées; see below) until the weight of the shell corresponds to the weight of the core. During the process, the liquid sprayed onto the tablet changes from a sticky liquid to a semi-solid and finally to a non-sticky dry surface. The disadvantage of conventional dragées is the poor shelf life due to the high sugar content and the long production times.
The actual process takes place in dragées vats, which resemble a large laundry drum. The rotation keeps the kernels moving and mixing evenly. In order to absorb the large amount of aqueous sugar solution, the core or blank is first sprayed with a cover layer of coating syrup with binder, anti-adhesive and structuring filler. The core is thus mechanically stable and protected from moisture. The masking layer is followed by the application layer, which consists only of coating syrup. Once several layers have been applied until the desired size has been reached, coloring can begin. Finally, another layer of smoothing syrup with clear pure syrups is applied to protect the coloring. To make the outer layer look more beautiful, another polishing layer with hard waxes is applied.
A similar type of dragées are the quick dragées, which are similar to the dragées in the principle of construction. Here also is a sugar solution applied several times until the shell is approximately 20-50% of the core weight. This enables shorter production times with less material input. The difference with conventional dragées is also the composition of the sugar layers: these are identical, unlike conventional dragées. Fast dragées are manufactured in the same way as conventional dragées. Both dragées are microbially susceptible due to their sugar content.
Both forms of sugar-coated dosage forms are produced in rotating kettles or non-rotating coaters. In the case of rotating kettles, a further distinction is made between conventional inclined and horizontal coating kettles. Non-rotating coaters are divided into fluidized bed processes (smooth, Wurster, ball coaters) and fluidized bed processes (see below).
In coating of film-coated tablets, the core is coated only with a polymer that does not change its shape & volume. The polymer, unlike dragée, consists of only a single layer and occupies only about 5-15% of the core. There are no requirements for the core shape, as the polymer solution dries more quickly than the sugar solution. During the process, the liquid sprayed onto the tablet changes from a sticky liquid to a semi-solid to finally a non-tacky dry surface. Advantages result from shorter manufacturing times, better shelf life and more differentiated dissolution properties depending on the type of film former.
The polymer solution usually consists of several substances contained in the polymer solution to be applied. These include:
Film former (see below) Plasticizer, to prevent curing polymer layer from becoming brittle. (e.g. citric acid ester) Anti-adhesive agents to prevent tablets from sticking together (e.g. talcum) Dispersing or smoothing agents (e.g. sorbitan monolaurate) Coating agent to protect the tablet or to enhance the subsequent coloring (e.g. titanium oxide) Dye
Solvent to dissolve the above substances. There is usually the possibility to work with aqueous and organic solvents.
The raw tablets are still sharp-edged due to the pressing process. These edges still have to be removed so that the polymer layer does not tear later. Once the tablets have been deburred, they are cleaned with air to remove dust residues. The tablets are placed in the coating kettles or fluid bed equipment.
Coating of tablets in the coating kettle differs from coating (see above) only in the liquid sprayed. There are several experimental setups for fluid bed processes (smooth, Wurster, spherical coater and fluidized bed processes), although they do not differ in principle: instead of mechanical rotation, the tablets are kept in motion by means of an air stream. These air streams are usually arranged in a circular pattern, so that the tablets always fall back to their starting position. Advantages result from the simple application of the polymer solution and the rapid drying of this.
If an aqueous or organic solvent is used, this must also be removed again. In all processes (including coating), this is done with the aid of air streams. Today, the eddy current process is increasingly being used.
The chemical substances of film formers are divided into chemical or functional groups. The chemical group is divided into: Cellulose derivatives, polyacrylates, polymethacrylates (known as eudragites), vinyl polymers (such as polyvinylpyrrolidone (PVP) and its derivatives) and the so-called shellac (this is a secretion of the insect Kerria lacca).
Although the chemical classification provides a good overview, the functional classification is more practical:
Fast-soluble film formers, such as PVP and its derivatives, and methacrylates.
Gastric juice-soluble and small intestine-soluble film formers, such as hydroxypropyl methylcellulose phthalate (HPMC), carboxymethylcellulose (Na-CMC), polyvinyl acetate phthalate, methacrylic acid ester and shellac
Insoluble film formers such as ethyl cellulose and methacrylic acid esters.
In general, there are no limits to the areas of application. Even frozen, meat and fish products can be coated accordingly. Large quantities are coated in the production of raw materials. But special coatings also give fruit and vegetables a "second protective skin". The processes used for coating are no different from those used in the pharmaceutical industry. If the requirements for the applied coating are not very high, simple spraying by means of nozzles can be used.
The coating substances must be suitable for foodstuffs and must not form toxic degradation products. Depending on the product, fats, waxes and water-soluble coating substances are thus used. If end products, such as fruit, are coated, there is no obligation to label the substances used.
Among the most common pharmaceutical dosage forms used today are tablets, dragées, pellets and pills. To make these dosage forms usable by the user, the odor, taste and color of the drug must be concealed. It is also advantageous to be able to release the active ingredient specifically at a desired location. Coating, or overcoating, is a process that applies a layer of coating material to the surface of the dosage form. This layer alone can fulfill all the requirements mentioned.
New research is being conducted in the direction of solvent-free coating. At the same time, this process enables resource-saving application (with all the other advantages). Several research projects have already been carried out to put this process into practice, two of which should be highlighted. Firstly, the core can be placed directly in a matrix, which then encases the core via a pressing process. This process would then be a hybrid of coating and tablet pressing. On the other hand, the polymer used can be applied to the cores in powder form and then converted into liquid form using external energy sources. If the liquid form is present, a film is automatically formed around the tablets. The form of energy introduced distinguishes the current processes and ranges from supercritical gases to UV light.
The manufacturing process is not only used in the pharmaceutical industry, but also in the food industry: here, too, attempts are made to modify the surface properties of raw materials.
Often, substances are needed in a free-flowing state to ensure improved dosing capability of substances. In this case, the substances already have the specified size, but cannot flow due to substance-specific properties (e.g. excessive adhesive forces between the individual particles). This results in inaccurate metering and consequently errors in the end product. If these fine-grained or crystalline materials are coated with appropriate substances, the materials can flow freely.
If grains are moved by bulk processes (e.g. during loading), friction occurs among the grains. The resulting dust can again cause flow problems or form explosive gases. A coating can reduce this effect and thus lead to higher productivity and safety in the manufacturing process.
As in the pharmaceutical sector, undesirable tastes and odors must also be masked in the food industry. A coating prevents these substances from being released onto the surface and thus leads to greater acceptance by the customer.
A coating also protects the substances from moisture, oxidation and undesirable chemical reactions in substance mixtures (see above).
A similar advantage arises from substances that are to be deliberately introduced into the coating: if these also meet the criteria of coating substances, they can be distributed more finely. These substances, which usually have an intensive effect, can thus be applied in a targeted and finely distributed manner.
Many foodstuffs contain substances that are initially dissolved on contact with water (e.g. sugar). Slow release (retarded delivery) is advantageous here, so that the end product does not dissolve too quickly (and lose its flavor, for example). With selected means, a coating material can meet these requirements.
Through uniform application, a coating can also be used for coloring (visual appeal to the customer). In the food industry, this is done with food coloring or, for example, paprika powder.
Coatings in the food sector are becoming more and more important. New natural materials can seal the products airtight and thus make secondary packaging (plastic) superfluous. Used plastic material can thus be avoided, which significantly improves the eco-balance of the goods. One current project is trying to spray a tincture of liquid silk (liquidseal) onto vegetables.
Historia ya kufunika inarudi nyuma hadi mwanzoni mwa miaka ya 1950, wakati dawa za kwanza zilipofunikwa na sukari ili kuficha ladha mbaya. Uangalifu zaidi na zaidi ulilipwa kwa michakato ambayo haikuwa tu ya haraka na yenye ufanisi zaidi, lakini pia ilikuwa na ushawishi mkubwa juu ya kutolewa kwa viungo hai. Utaratibu wa kawaida kulingana na maji na vimumunyifu vya kikaboni ulitengenezwa kwa kusudi hili. Utaratibu huu ni moja ya njia zinazotumiwa sana leo na unaboreshwa daima. Utafiti mpya unajaribu kutumia vifaa vya kufunika moja kwa moja katika fomu kavu, bila kwanza kuvifuta katika maji au vimumunyisho vya kikaboni. Utaratibu huu usio na vimumunyifu unaweza kuchukua nafasi ya mbinu za kawaida katika siku zijazo, kwa kuwa ni ufanisi, kuokoa rasilimali, haraka kutekeleza na kuokoa nishati. "Kupaka ni suala kubwa sana hata katika dawa, kwani swali linatokea: ni lini, ni jinsi gani, kwa muda gani, na ni wapi kiungo kinachotumika kinapaswa kutolewa?""" Hata kiasi kilichotolewa katika kila kesi kinaweza kudhibitiwa. Sehemu zote za vidonge vinaweza kufunikwa: ikiwa, kwa mfano, dawa yenyewe, granules au vidonge vinavyotokana na vidonge vinaweza kufunikwa tofauti, kutolewa kwa kiungo hai kunaweza kudhibitiwa tofauti. Utaratibu wa kufunika hutumiwa kwa sababu tatu kuu: Kuboresha kufuata usalama wa dawa, kazi ya kinga na uboreshaji wa dawa za kibiolojia. Kuongeza usalama wa dawa ni sababu kuu kwa nini vidonge ni coated: coating kutumika hufanya vidonge kuangalia nicer, huficha ladha mbaya na kuwezesha utambulisho (mengi ya viungo kazi na excipients ni nyeupe). Kwa sababu ya uwezo wa mgonjwa wa kuondoa maji kwenye mdomo, dawa hiyo inaweza kuingizwa kwa urahisi, na kwa sababu ya uwezo wa mgonjwa wa kuondoa maji kwenye mdomo, dawa hiyo inaweza kuingizwa kwenye mdomo. Matokeo ni kumeza vizuri bila uwezekano wa kushikamana na sehemu ya ndani ya mdomo-mkojo. Kifuniko pia inalinda kiungo hai kutoka oksijeni ya angahewa, unyevu, mwanga na asidi ya tumbo. Pia inazuia abrasion ya mitambo, kwa mfano wakati wa usafirishaji: vumbi linalotokana na inaweza kuwa na madhara kwa afya kama inhaled. Kwa sababu ya kuhifadhiwa kwa dawa, dawa hiyo inaweza kuhifadhiwa kwa muda mrefu, na ikiwa viungo kadhaa vya dawa vimeunganishwa kwenye kibao kimoja, athari za kemikali zinaweza kutokea. Filamu ya kinga yaweza kuzuia jambo hilo na kuongeza utii wa mgonjwa kwa kuondoa uhitaji wa kuchukua vidonge vingi. Biopharmaceutical kuweka pia ni faida: coating kutumika si tu inalinda mucosa ya tumbo kutoka viungo kazi, lakini pia inalinda dawa dhidi ya asidi ya tumbo ya fujo. Ikiwa vifaa vya kufunika vinachaguliwa vizuri, utoaji wa dawa unaweza kubadilishwa au kudhibitiwa haswa (kwa mfano, Urefu wa utando wa utando (kufunikwa kwa utando wa utando) Katika dawa, coating ni moja ya coated imara dosage aina na aina kuu kuwa dragées na dragées kawaida. Dragées ni zaidi subdivided katika dragées kawaida na dragées haraka. Katika dragées ya kawaida, kiini halisi ni coated na sukari hivyo kwamba umbo na kiasi yanayotokana ni tofauti kabisa na kiini awali. Hilo pia hufanya iwe vigumu kuchora kwa njia inayotakiwa, kwa kuwa tabaka la sukari ni nene sana. Ili kuweza kutumia kiasi hicho cha sukari, kiini lazima kiwe na urefu na umbo fulani la kamba. Katika kesi hii, suluhisho la sukari hutumiwa katika tabaka kadhaa za muundo tofauti (tofauti na dragées ya haraka; angalia hapa chini) hadi uzito wa ganda unalingana na uzito wa msingi. Wakati wa mchakato, kioevu kunyunyizia juu ya kibao mabadiliko kutoka kioevu sticky kwa nusu-imara na hatimaye kwa uso kavu non-sticky. Hasara ya dragées ya kawaida ni maisha duni ya rafu kutokana na maudhui ya sukari ya juu na nyakati ndefu za uzalishaji. Utaratibu halisi hufanywa katika mitungi ya dragées, ambayo hufanana na ngoma kubwa ya kufulia nguo. Mzunguko huo hufanya mbegu hizo ziendelee kuhamia na kuchanganyika kwa usawa. Ili kuingiza kiasi kikubwa cha ufumbuzi wa sukari ya maji, msingi au blank kwanza hutiwa dawa na safu ya kifuniko cha syrup ya kufunika na binder, anti-adhesive na filler ya muundo. Kwa hiyo, kiini cha chombo hicho ni thabiti na kimehifadhiwa kutokana na unyevu. tabaka masking ni ikifuatiwa na tabaka la maombi, ambayo inajumuisha tu ya coating syrup. Mara tu tabaka kadhaa zinapowekwa hadi ukubwa unaotaka ufikie, rangi yaweza kuanza. Mwishowe, tabaka jingine la syrup ya kusafisha yenye syrups safi iliyo wazi hutumiwa kulinda rangi. Ili kufanya tabaka la nje liwe zuri zaidi, tabaka jingine la kupaka rangi kwa kutumia nta ngumu hutumiwa. Aina sawa ya dragées ni dragées haraka, ambayo ni sawa na dragées katika kanuni ya ujenzi. Hii ni kwa sababu ya mchanganyiko wa sukari, ambayo hutumiwa mara kadhaa hadi shell inakuwa karibu 20-50% ya uzito wa msingi. Hii inawezesha muda mfupi wa uzalishaji na pembejeo ndogo ya vifaa. Tofauti na dragées ya kawaida pia ni muundo wa tabaka za sukari: hizi ni sawa, tofauti na dragées ya kawaida. Dragées haraka ni viwandani kwa njia sawa na dragées kawaida. Dragées zote mbili ni microbially nyeti kutokana na maudhui yao ya sukari. Aina zote mbili za fomu za kipimo vilivyopakwa sukari hutengenezwa katika keteli zinazozunguka au coaters zisizo za kuzunguka. Katika kesi ya kettles kuzunguka, tofauti zaidi ni kufanywa kati ya kawaida tilted na usawa coating kettles. Non-rotating coaters ni kugawanywa katika fluidized kitanda michakato (smooth, Wurster, mpira coaters) na fluidized kitanda michakato (tazama chini). Katika coating ya vidonge film-coated, kiini ni coated tu na polima ambayo haina kubadilisha sura yake na kiasi. Polima, tofauti na dragée, ina safu moja tu na inachukua karibu 5-15% ya kiini. Hakuna mahitaji kwa ajili ya sura ya msingi, kama suluhisho polymer kavu haraka zaidi kuliko suluhisho sukari. Wakati wa mchakato, kioevu kunyunyizia juu ya kibao mabadiliko kutoka kioevu sticky kwa nusu-imara kwa hatimaye non-tacky kavu uso. Faida hutokana na muda mfupi wa utengenezaji, maisha bora ya rafu na mali tofauti zaidi ya kutenganisha kulingana na aina ya mtengenezaji wa filamu. Suluhisho la polima kwa kawaida lina vitu kadhaa vilivyo katika suluhisho la polima linalotumiwa. Hizi ni pamoja na: Filamu ya zamani (tazama hapa chini) Plasticizer, kuzuia kuponya safu ya polima kutoka kuwa brittle. (kwa mfano. Citric acid ester (ACE) - dawa ya kuzuia kuunganisha kwa dawa Talcum) dispersing au smoothing wakala (kwa mfano Sorbitan monolaurate (SOM) - dawa ya kufunika ili kulinda vidonge au kuongeza rangi ya baadaye (kwa mfano, Titanium oxide) Dye Solvent kwa kufuta vitu hapo juu. Kwa kawaida kuna uwezekano wa kufanya kazi na vimumunyisho vya maji na kikaboni. Vidonge visivyotiwa mafuta bado vina pembe kali kwa sababu ya mchakato wa kushinikiza. Bado pande hizo zinahitaji kuondolewa ili safu ya polima isianguke baadaye. Mara tu vidonge vimepasuliwa, vinasafishwa kwa hewa ili kuondoa mabaki ya vumbi. Vidonge ni kuwekwa katika coating kettles au vifaa vya kitanda cha kioevu. Coating ya vidonge katika coating kettle inatofautiana na coating (tazama hapo juu) tu katika kioevu kunyunyizia. Kuna seti kadhaa za majaribio kwa michakato ya kitanda cha kioevu (smooth, Wurster, spherical coater na michakato ya kitanda cha kioevu), ingawa hazitofautiani kwa kanuni: badala ya mzunguko wa mitambo, vidonge huhifadhiwa kwa njia ya mtiririko wa hewa. Kwa kawaida mtiririko huo wa hewa umepangwa kwa mviringo, hivyo kwamba mabamba hayo huanguka tena mahali pake pa mwanzo. Faida hutokana na matumizi rahisi ya suluhisho la polima na kukausha kwa haraka kwa hii. Kama kioevu cha maji au kikaboni hutumiwa, hii pia lazima kuondolewa tena. Katika michakato yote (ikiwa ni pamoja na coating), hii ni kufanyika kwa msaada wa mikondo ya hewa. Leo, utaratibu wa mtiririko wa eddy unatumiwa zaidi na zaidi. Dutu za kemikali za watengenezaji wa filamu zimegawanywa katika vikundi vya kemikali au vya kazi. Chombo cha kemikali ni pamoja na: polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines, polymethylamines. Ingawa uainishaji wa kemikali hutoa muhtasari mzuri, uainishaji wa kazi ni wa vitendo zaidi: Watengenezaji wa filamu wa haraka, kama vile PVP na derivatives zake, na methacrylates. Inaweza kuunganishwa na maji ya tumbo, na inaweza kuunganishwa na utumbo mdogo, kama vile hydroxymethylcellulose phthalate (HMC), carboxymethylcellulose (CMC), polyvinyl acetate phthalate (PVA), methacrylic ester asidi, na shellac. Kwa ujumla, hakuna mipaka kwa maeneo ya matumizi. Hata bidhaa zilizofungwa, nyama na samaki zaweza kupakwa rangi inayofaa. Kiasi kikubwa ni coated katika uzalishaji wa malighafi. Lakini vitambaa maalumu pia huwapa matunda na mboga " ngozi ya pili ya kulinda". Utaratibu unaotumiwa kwa ajili ya mipako si tofauti na ule unaotumiwa katika viwanda vya dawa. Kama mahitaji kwa ajili ya mipako kutumika si ya juu sana, dawa rahisi kwa njia ya nozzles inaweza kutumika. Vitu vya kufunika lazima viwe vinavyofaa kwa vyakula na havipaswi kuunda bidhaa zenye sumu za uharibifu. Kulingana na bidhaa, mafuta, waxes na maji-kuyeyuka coating vitu ni hivyo kutumika. Ikiwa bidhaa za mwisho, kama vile matunda, zimefunikwa, hakuna wajibu wa kutia alama vitu vilivyotumiwa. Miongoni mwa aina za kawaida za dawa zinazotumiwa leo ni vidonge, dragées, pellets na vidonge. Ili fomu hizi za kipimo ziweze kutumiwa na mtumiaji, harufu, ladha na rangi ya dawa lazima zifichwe. Pia ni faida kuwa na uwezo wa kutolewa viungo kazi hasa katika eneo linalotakiwa. Coating, au overcoating, ni mchakato ambao inatumika safu ya vifaa vya mipako kwa uso wa fomu ya kipimo. Safu hii peke yake inaweza kutimiza mahitaji yote yaliyotajwa. Utafiti mpya unafanywa katika mwelekeo wa mipako isiyo na vimumunyifu. Wakati huo huo, mchakato huu inaruhusu maombi ya kuokoa rasilimali (na faida nyingine zote). Miradi kadhaa ya utafiti tayari imefanywa ili kuweka mchakato huu katika mazoezi, ambayo mawili yanapaswa kuangaziwa. Kwanza, kiini inaweza kuwekwa moja kwa moja katika matrix, ambayo kisha encloses kiini kupitia mchakato wa kushinikiza. Utaratibu huu basi itakuwa mseto wa mipako na tablet kushinikiza. Kwa upande mwingine, polima kutumika inaweza kutumika kwa cores katika poda fomu na kisha kugeuzwa katika fomu ya kioevu kwa kutumia vyanzo vya nje ya nishati. Ikiwa fomu ya kioevu iko, filamu hufanyizwa moja kwa moja kuzunguka vidonge. Aina ya nishati iliyowekwa inatofautisha michakato ya sasa na inatofautiana kutoka kwa gesi za supercritical hadi nuru ya UV. Utaratibu wa utengenezaji hautumiki tu katika sekta ya dawa, lakini pia katika sekta ya chakula: hapa, pia, majaribio yanafanywa kurekebisha mali ya uso wa malighafi. Mara nyingi, vitu vinahitajika katika hali ya mtiririko huru ili kuhakikisha uwezo wa kipimo cha vitu ulioboreshwa. Katika kesi hii, vitu tayari kuwa na ukubwa maalum, lakini hawawezi mtiririko kutokana na mali maalum ya dutu (kwa mfano nguvu ya kupita kiasi ya kushikamana kati ya chembechembe za mtu binafsi). Hii husababisha kupima usahihi na kwa hiyo makosa katika bidhaa ya mwisho. Ikiwa vifaa hivi vyenye chembechembe ndogo au vya kioo vimefunikwa kwa vitu vinavyofaa, vifaa hivyo vinaweza kutiririka kwa uhuru. Kama nafaka ni kuhamishwa na michakato wingi (kwa mfano wakati wa kupakia), msuguano hutokea kati ya nafaka. Vumbi linalotokezwa linaweza kusababisha matatizo ya mtiririko au kufanyiza gesi zenye mlipuko. Coating inaweza kupunguza athari hii na hivyo kusababisha uzalishaji wa juu na usalama katika mchakato wa utengenezaji. Kama ilivyo katika sekta ya dawa, ladha na harufu zisizohitajika lazima pia zifichwe katika sekta ya chakula. Coating huzuia vitu hivi kutolewa kwenye uso na hivyo husababisha kukubalika zaidi na mteja. Coating pia inalinda vitu kutoka unyevu, oxidation na athari zisizohitajika kemikali katika mchanganyiko wa vitu (tazama hapo juu). Faida sawa hutokea kutoka kwa vitu ambavyo vinapaswa kuingizwa kwa makusudi katika mipako: ikiwa hizi pia zinakidhi vigezo vya vifaa vya mipako, zinaweza kusambazwa kwa uangalifu zaidi. Vitu hivi, ambavyo kwa kawaida huwa na athari kali, vinaweza kutumiwa kwa njia iliyoelekezwa na kusambazwa vizuri. Vyakula vingi vina vitu ambavyo vimeyeyuka wakati vinapogusa maji (kwa mfano, sukari). Utoaji wa polepole (usafirishaji uliocheleweshwa) ni faida hapa, ili bidhaa ya mwisho isiwe na kuyeyuka haraka sana (na kupoteza ladha yake, kwa mfano). Kwa njia zilizochaguliwa, nyenzo ya mipako inaweza kukidhi mahitaji haya. Kupitia matumizi ya usawa, mipako pia inaweza kutumika kwa rangi (kuvutia kuona kwa mteja). Katika viwanda vya vyakula, hilo hufanywa kwa rangi ya vyakula au, kwa mfano, unga wa paprika. Coatings katika sekta ya chakula ni kuwa zaidi na zaidi muhimu. Vifaa vipya vya asili vinaweza kufunga bidhaa hizo bila hewa na hivyo kufanya vifurushi vya pili (plastic) visivyo na maana. Kwa hivyo nyenzo za plastiki zilizotumika zinaweza kuepukwa, ambayo inaboresha sana usawa wa ikolojia wa bidhaa. Mradi mmoja wa sasa unajaribu kunyunyizia mboga tincture ya hariri ya kioevu (liquidseal).