What is Zantac?
Zantac and other ranitidine-based products belong to a class of drugs colloquially referred to as H2 (histamine-2) blockers. H2 blockers inhibit the cells in one’s stomach from being stimulated, thereby decreasing the amount of stomach acid produced. Because of this ability, Zantac is commonly used to treat the following conditions and symptoms:
- Acid Reflux
- Stomach Ulcers
- Sour Stomach
- GERD (Gastroesophageal reflux disease)
- Zollinger-Ellison Syndrome
- Gastric and Duodenal Ulcers
- Barrett’s Esophagus
Zantac was originally approved by the FDA in 1983, and hit $1 billion in annual sales in just five years’ time. In the decades following, Zantac became arguably the most popular antacid medication on the market– due to its popularity and availability, it is estimated that as many as 15,000,000 Zantac/ ranitidine prescriptions were written per year. After Zantac’s original US patent expired in 1997, dozens of generic ranitidine drugs were introduced into the market.
The Risks Associated with Zantac
Ranitidine, the active ingredient in Zantac, is an unstable chemical, meaning that over time its compounds break down and degrade. The byproduct of this degradation is N-nitrosodimethylamine, or NDMA.
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NDMA is a chemical that the FDA and WHO have classified as a human carcinogen since the 1970s. It acts as a carcinogen by modifying the victim’s DNA and causing inflammation, resulting in tumor growth and promotion. Other drugs have had NDMA contamination due to production or storage errors, but in the case of Zantac, the ranitidine molecule itself contains the binding elements to form the carcinogen. In other words, it’s prepackaged and doesn’t need any outside factors to form. NDMA is found naturally, and because of that the FDA has established a daily intake limit of 96 nanograms (ng). However, recent studies of Zantac using FDA-approved methods have found more than 250 to 3,100 ng of NDMA in a single 150 mg tablet, the dosage innumerable people take every day. When stored under high temperatures, Zantac has been able to produce over 3,000,000 ng of NDMA per tablet. After decades of being available for public consumption, the FDA ordered manufacturers on April 1, 2020 to recall all Zantac and generic OTC ranitidine drugs from the market immediately. Litigation is currently ongoing.
Trusted Zantac Lawyers
If you or a loved one has a history of taking Zantac and has since been diagnosed with cancer, consult with a medical professional to address any immediate concerns. Then contact the experienced staff of Las Vegas Zantac attorneys at Van Law Firm.
Call our Las Vegas office at (725) 900-9000 for a free consultation to discuss your potential case. Our personal injury and wrongful death lawyers can help recover multiple forms of damages such as medical costs, lost wages, and pain and suffering.
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Zantac ni nini? Zantac na bidhaa nyingine za msingi wa ranitidine ni sehemu ya darasa la dawa za kulevya zinazojulikana kama H2 (histamine-2) blockers. H2 blockers kuzuia seli katika tumbo la mtu kutoka kuchochewa, hivyo kupunguza kiasi cha asidi ya tumbo zinazozalishwa. Zantac ni dawa ya kawaida ya matibabu ya magonjwa ya tumbo, kama vile Acid Reflux, Magonjwa ya Matumbo, Magonjwa ya Matumbo, Gastroesophageal Reflux, Zollinger-Ellison Syndrome, Magonjwa ya Matumbo na Duodenal, na Barrett's Esophagus. Katika miongo iliyofuata, Zantac ikawa dawa maarufu zaidi ya antacid kwenye soko, kwa sababu ya umaarufu wake na upatikanaji, inakadiriwa kuwa kama dawa za 15,000,000 za Zantac au ranitidine ziliandikwa kwa mwaka. Baada ya patent ya awali ya Zantac nchini Marekani kumalizika mwaka 1997, kadhaa ya dawa za generic za ranitidine zilianzishwa kwenye soko. Ranitidine, kiungo hai katika Zantac, ni kemikali isiyo imara, ikimaanisha kwamba kwa muda, misombo yake huvunjika na kuharibika. Toleo la ziada la uharibifu huu ni N-nitrosodimethylamine, au NDMA. Kwa ushauri wa kisheria wa bure, piga simu (725) 900-9000 NDMA ni kemikali ambayo FDA na WHO wameweka katika orodha ya kemikali za kansa za binadamu tangu miaka ya 1970. Inafanya kazi kama carcinogen kwa kubadilisha DNA ya mhasiriwa na kusababisha uvimbe, na kusababisha ukuaji wa uvimbe na kukuza. Dawa nyingine za kulevya zimekuwa na uchafuzi wa NDMA kutokana na makosa ya uzalishaji au uhifadhi, lakini katika kesi ya Zantac, molekuli ya ranitidine yenyewe ina vipengele vya kuunganisha kuunda carcinogen. Kwa maneno mengine, ni prepackaged na haina haja ya mambo yoyote ya nje ya kuunda. Kwa sababu ya kuenea kwa NDMA, FDA imeweka kikomo cha kila siku cha 96 nanograms. Utafiti wa hivi karibuni wa Zantac, kwa kutumia mbinu zilizokubaliwa na FDA, umegundua zaidi ya 250-3100 ng ya NDMA katika kibao kimoja cha 150 mg, kipimo ambacho watu wengi huchukua kila siku. Wakati kuhifadhiwa chini ya joto la juu, Zantac imekuwa na uwezo wa kuzalisha zaidi ya ng 3,000,000 ya NDMA kwa kibao. Baada ya miaka kadhaa ya kutolewa kwa matumizi ya umma, FDA iliamuru wazalishaji Aprili 1, 2020 kukumbuka dawa zote za Zantac na generic OTC za ranitidine kutoka soko mara moja. Kesi hiyo inaendelea kwa sasa. Ikiwa wewe au mtu unayempenda una historia ya kuchukua Zantac na tangu wakati huo umegunduliwa kuwa na kansa, wasiliana na mtaalamu wa matibabu ili kushughulikia wasiwasi wowote wa haraka. Kwa hivyo, tafadhali wasiliana na wakili wa Las Vegas Zantac katika kampuni ya sheria ya Van. Piga simu ofisi yetu ya Las Vegas kwa 725-9000 kwa ushauri wa bure ili kujadili kesi yako ya uwezekano. Wanasheria wetu wa majeraha ya kibinafsi na mauaji ya makosa wanaweza kusaidia kurudisha aina nyingi za uharibifu kama vile gharama za matibabu, mishahara iliyopotea, na maumivu na mateso. Hakuna wajibu ushauri ni daima bure.Hebu kukusaidia! Piga simu kwa sasa: (725) 900-9900