Medical applications of exosomes
Exosome therapy is gaining popularity in regenerative medicine. So what exactly are exosomes? Exosomes are particles that are released but cannot be replicated. They are intrical in how cells talk to each other. One cell will have a bunch of vesicles that leave and head to another cell to deliver a “message.” These vesicles contain information in the form of chemicals, cytokines to particles of messenger RNA.
Where are Exosomes found?
Exosomes are produced from stem cells and can be found in a variety of tissues.
How are they different from Stem Cells?
Exosomes are contained in stem cells. They are messenger cells that travel to communicate with other cells to produce the needed proteins to repair damaged areas. The use of exosomes does not require donor cells to be injected in the body. Exosomes can be extracted from mesenchymal stem cells (MSCs), sterilized and then injected into the body.
Stem cell therapy injects donor cells into a specific location. These stem cells grow and divide to repair the injured area and create healthier cells overtime. Exosomes are extracted from mesenchymal stem cells and like stem cells are injected into the injured area. Exosomes get to work at communicating with the patient’s own cells and enhance communication among the cells to generate the necessary and needed cells for healing.
What Exactly is Exosome Therapy ?
Exosome products are generally used for orthopedic injuries. Much like stem cell therapy, the exosomes would be injected into the injured site. This is generally an outpatient therapy that is relatively painless.
What does Exosome Therapy Treat? (Medical applications)
Exosome therapy is used for a variety of musculoskeletal injuries, chronic pain, degenerative diseases and genetic disorders. Aging and injuries suppress your cells ability to communicate with each other. The whole purpose of exosomes is to promote communication between cells to repair damaged tissues.
Exosomes are also used to help repair the skin from effects of aging. Overtime, the dermal layer of the skin is damaged because of fragmentation in the collagen, resulting in the signs of aging and hindering the ability to heal wounds. Exosomes have been found to help the body ramp up its collagen production. Exosomes also help inhibit inflammatory cytokines. This means exosomes can help with Atopic Dermatitis, a common skin disorder.
Exosomes can also help with lyme disease. Lyme disease is a very complex disease that compromises the immune system. This can lead to the disruption of cellular health and function. Oftentimes, lyme disease patients experience difficulty with inflammation which exosomes are also known to treat.
Are Exosomes Safer than Stem Cells
While both therapies have a low risk of complications, exosome therapy does not involve a surgical procedure for harvesting cells. Stem cells’ primary job is to grow and divide new and healthy cells from the donor cells. At times these cells may rapidly multiply resulting in a tumor. Exosomes do not multiply, rather they are responsible for improving the communication among cells.
If you want to become a specialist in stem cell therapies, exosomes and MSCs with us, check our next training dates here
Wharton’s Jelly Treatment
Wharton’s Jelly is the substance that helps lubricate and support the umbilical cord. What makes Wharton’s Jelly so special is it contains high levels of mesenchymal stem cells. These special stem cells adapt to fit the cells needed to help regenerate damaged tissue and relieve pain naturally.
The mesenchymal stem cells that come from Wharton’s Jelly contain the most potent stem cells that are rich in regenerative properties. Wharton’s Jelly also contains a good amount of collagen, hyaluronic acid, and anti-inflammatory properties. This makes them quintessential in regenerative medicine.
Regenerative medicine refers to treatments and medicine that is naturally occuring, stem cell therapies being included. Mesenchymal stem cells are harvested from the Wharton Jelly found in the umbilical cord that has been donated by a healthy mother of a full term baby. These stem cells contain all the regenerative properties needed to help the body heal and relieve pain naturally.
How does this treatment work?
Mesenchymal stem cells are injected into the body and have the ability to transmute into cells that are needed to repair damaged tissue and relieve inflammation. These cells harness the potent regenerative properties that help rebuild the injured part of the body and provide long lasting natural pain relief. Unlike pain medicines which provide temporary relief that mask the symptoms and are harmful to the body if taken long term, the stem cells found in Wharton’s Jelly are naturally occurring and natural to the body.
What is Wharton’s Jelly best used for?
Wharton’s Jelly is best used in patients with degenerative diseases and musculoskeletal injuries. The anti-inflamatory and regenerative properties go to work at repairing damaged tissues. Repaired tissue means lasting pain relief and restored function.
What can someone expect?
Once a patient and doctor have decided on this type of stem cell treatment, patients can expect a relatively painless process. Stem cells are injected into the site and immediately go to work. Injections are virtually painless and there are no known negative side effects. Patients can generally get right back to the activities they love. Doctors will discuss treatment plans based on individual needs and in some cases resting an injured area for a particular period of time will be needed.
The mesenchymal stem cells found in Whorton’s Jelly have proven to be a very successful therapeutic method to treat a number of degenerative issues and injuries. This therapy is relatively painless, with no known negative side effects making it an excellent choice in treatment. Instead of masking the pain with dangerous medicine, stem cell therapy offers a naturally occurring solution that aims to repair the damaged tissue and resolve the problem.
If you want to learn more about Wharton’s Jelly Treatment and how can you help your patients, you can check our next training course here
Matumizi ya matibabu ya exosomes Tiba ya exosome inapata umaarufu katika dawa ya kurudisha. Kwa hiyo, exosomes ni nini hasa? Exosomes ni chembechembe ambazo hutolewa lakini haziwezi kuiga. Ni ngumu sana kuona jinsi chembe zinavyowasiliana. Chembe moja ina vesicles nyingi ambazo zinaelekea kwenye chembe nyingine ili kutoa ujumbe, na vesicles hizo zina habari katika fomu ya kemikali, cytokines na chembe za RNA. Exosomes hupatikana wapi? Exosomes hutengenezwa kutoka kwa chembe za msingi na zinaweza kupatikana katika tishu mbalimbali. Zina tofauti gani na Chembe za Msingi? Exosomes ziko katika chembe za msingi. Seli hizo ni za ujumbe, ambazo hutumia nguvu za mwili kutengeneza protini zinazohitajiwa kurekebisha sehemu zilizoharibiwa. Matumizi ya exosomes haihitaji chembe za mchangiaji kutiwa ndani ya mwili. Exosomes inaweza kuchukuliwa kutoka kwa seli za msingi za mesenchymal (MSCs), kuzaa na kisha kuingizwa ndani ya mwili. Tiba ya chembe za shina huingiza chembe za mchangiaji katika eneo hususa. Chembe hizi za msingi hukua na kugawanyika ili kurekebisha eneo lililojeruhiwa na kuunda chembe zenye afya zaidi kwa muda mrefu. Exosomes hutolewa kutoka kwa seli za msingi za mesenchymal na kama seli za msingi huingizwa katika eneo lililojeruhiwa. Exosomes hufanya kazi ya kuwasiliana na seli za mgonjwa mwenyewe na kuongeza mawasiliano kati ya seli ili kuzalisha seli muhimu na zinazohitajika kwa uponyaji. Tiba ya Exosome ni nini hasa? Bidhaa za Exosome kwa ujumla hutumiwa kwa majeraha ya mifupa. Sawa na tiba ya chembe za shina, exosomes zingepandikizwa katika eneo lililojeruhiwa. Kwa kawaida, matibabu hayo hayana maumivu. Tiba ya Exosome hutibu nini? Tiba ya Exosome hutumiwa kwa majeraha mbalimbali ya misuli na mifupa, maumivu ya muda mrefu, magonjwa ya degenerative na matatizo ya urithi. Kuzeeka na majeraha huzuia chembe zako zisizozungumza. Kusudi lote la exosomes ni kuendeleza mawasiliano kati ya chembe ili kurekebisha tishu zilizoharibiwa. Exosomes pia hutumiwa kusaidia kurekebisha ngozi kutokana na athari za kuzeeka. Kwa muda mrefu, tabaka la ngozi la ngozi huathiriwa kwa sababu ya kugawanyika kwa collagen, na kusababisha dalili za kuzeeka na kuzuia uwezo wa kuponya majeraha. Exosomes zimegunduliwa kusaidia mwili kuongeza uzalishaji wake wa collagen. Exosomes pia husaidia kuzuia cytokines ya uchochezi. Hii inamaanisha exosomes inaweza kusaidia na Atopic Dermatitis, ugonjwa wa ngozi wa kawaida. Exosomes pia inaweza kusaidia na ugonjwa wa Lyme. Ugonjwa wa Lyme ni ugonjwa tata sana ambao huharibu mfumo wa kinga. Hilo laweza kusababisha kuvurugwa kwa afya na utendaji wa chembe. Mara nyingi, wagonjwa wa ugonjwa wa Lyme hupata ugumu na uvimbe ambao exosomes pia inajulikana kutibu. Exosomes ni salama kuliko seli za shina Ingawa matibabu yote mawili yana hatari ya chini ya matatizo, matibabu ya exosomes haihusishi utaratibu wa upasuaji wa kuvuna seli. Kazi kuu ya chembe za msingi ni kukua na kugawanyika kwa chembe mpya na zenye afya kutoka kwa chembe za mchangiaji. Nyakati nyingine chembe hizo zaweza kuongezeka haraka na kutokeza uvimbe. Exosomes hazizidi, badala yake zinawajibika kwa kuboresha mawasiliano kati ya chembe. Ikiwa unataka kuwa mtaalamu wa matibabu ya seli za shina, exosomes na MSCs na sisi, angalia tarehe zetu za mafunzo ya pili hapa: Wharton's Jelly Treatment - Jelly ni dutu ambayo husaidia lubricate na kusaidia kamba ya umbilical. Kilichofanya Jelly ya Wharton kuwa ya pekee ni kwamba ina viwango vya juu vya chembe za msingi za mesenchymal. Chembe hizi za msingi za kipekee hujipatanisha na chembe zinazohitajika kusaidia kurejesha tishu zilizoharibiwa na kupunguza maumivu kwa njia ya asili. Chembe za msingi za mesenchymal zinazotokana na Wharton's Jelly zina chembe za msingi zenye nguvu zaidi ambazo zina mali nyingi za kuzalisha upya. Jelly ya Wharton pia ina kiasi kizuri cha collagen, asidi ya hyaluronic, na mali za kupambana na uvimbe. Hilo huwafanya wawe muhimu sana katika tiba ya kurudisha uhai. Tiba ya regenerative inahusu matibabu na dawa ambayo ni asili kutokea, tiba ya seli ya shina kuwa ni pamoja na. Seli za msingi za mesenchymal zinapatikana katika kamba ya umbilical iliyotolewa na mama mwenye afya ya mtoto wa muda kamili. Chembe hizi za msingi zina sifa zote za kuzaliana zinazohitajika kusaidia mwili kupona na kupunguza maumivu kwa asili. Matibabu hayo hufanyaje kazi? Chembe za msingi za mesenchymal huingizwa ndani ya mwili na kuwa na uwezo wa kubadilika kuwa seli zinazohitajika kurekebisha tishu zilizoharibiwa na kupunguza uvimbe. Chembe hizi hutumia uwezo wake wa kuzalisha upya, na hivyo kusaidia kujenga sehemu ya mwili iliyoharibiwa na kutoa misaada ya muda mrefu ya maumivu. Tofauti na dawa za maumivu ambazo hutoa misaada ya muda ambayo huficha dalili na ni hatari kwa mwili ikiwa inachukuliwa kwa muda mrefu, seli za shina zinazopatikana katika Jelly ya Wharton zinatokea kwa asili na ni asili kwa mwili. Jelly ya Wharton hutumiwa kwa njia gani? Jelly ya Wharton hutumiwa vizuri zaidi kwa wagonjwa wenye magonjwa ya degenerative na majeraha ya misuli na mifupa. Vipengele vya kuzuia uvimbe na kurudisha upya hufanya kazi katika kurekebisha tishu zilizoharibiwa. Tambo zilizorekebishwa humaanisha kupunguza maumivu kwa muda mrefu na kurudisha utendaji. Mtu aweza kutarajia nini? Baada ya mgonjwa na daktari kuamua kutumia aina hii ya matibabu ya chembe za msingi, wagonjwa wanaweza kutarajia matibabu yasiyo na maumivu. Chembe za msingi huingizwa mahali hapo na kuanza kufanya kazi mara moja. Injection ni painless na hakuna athari mbaya inayojulikana. Kwa kawaida wagonjwa wanaweza kurudi moja kwa moja kwenye shughuli wanazopenda. Madaktari watajadili mipango ya matibabu kulingana na mahitaji ya mtu binafsi na katika baadhi ya kesi kupumzika eneo lililojeruhiwa kwa kipindi fulani cha wakati kutahitajika. Chembe za msingi za mesenchymal zilizopatikana katika jelly ya Whorton zimethibitika kuwa njia ya matibabu yenye mafanikio sana kutibu masuala kadhaa ya degenerative na majeraha. Tiba hii ni kiasi painless, bila athari mbaya inayojulikana kufanya ni chaguo bora katika matibabu. Badala ya kuficha maumivu kwa dawa hatari, tiba ya seli za shina inatoa suluhisho la asili ambalo linakusudia kurekebisha tishu iliyoharibiwa na kutatua tatizo. Kama unataka kujifunza zaidi kuhusu Wharton ya Jelly Matibabu na jinsi unaweza kusaidia wagonjwa wako, unaweza kuangalia kozi yetu ya mafunzo ijayo hapa