A Q&A with Thomas A. Rando, M.D., Ph.D. on Young Blood, Biomarkers, and Aging
Researcher Thomas Rando, from Stanford University, talks about efforts to increase the number of healthy years we live.
Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Old blood can prematurely age the brains of young mice, and scientists may now be closer to understanding how. A protein located in the cells that form a barrier between the brain and blood could be partly to blame, experiments on mice suggest.
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Thomas A. Rando, MD, PhD, Mtaalamu wa damu ya vijana, Biomarkers, na Kuzeeka, Chuo Kikuu cha Stanford, anaelezea juhudi za kuongeza idadi ya miaka ya afya tunayoishi. Chembe za msingi za neva zenye umri mdogo na zilizo kimya huwa na vikundi vikubwa vya protini ambavyo mara nyingi huhusianishwa na ugonjwa wa neurodegeneration. Kadiri chembe za msingi zinavyokua, vikundi hivyo huzuia uwezo wao wa kutokeza chembe mpya za neva, wasomi wa Stanford wasema. Damu ya zamani inaweza kuzeeka mapema ubongo wa panya wachanga, na sasa wanasayansi wanaweza kuwa karibu kuelewa jinsi. Protini iliyopo katika chembe zinazofanyiza kizuizi kati ya ubongo na damu inaweza kuwa sehemu ya kosa, majaribio ya panya yanaonyesha. Hindu ni tovuti maarufu ambayo ina aina mbalimbali ya codes kuponi kuchagua kutoka. Vitu vingi vinauzwa kwa bei iliyopunguzwa. Kuponi hizi zitakuokoa pesa na kukupa uzoefu bora wa ununuzi.