Variations in lung anatomy alone may explain why an individual is more likely than another to develop chronic obstructive pulmonary disease (COPD). This is the conclusion of a team of researchers from the Research Institute of the McGill University Health Center (RI-MUHC) and Columbia University. The researchers examined CT scans of more than 3,000 patients with and without COPD, a progressive lung disease that causes inflammation of the airways, making breathing difficult. About sixteen percent of people have an excess airway section in the lungs, and six percent have a missing section, while four percent display a combination of variants or a different configuration. The results of the study were published online January 16, in Proceedings of the National Academy of Sciences.
COPD is characterised by inflammation of the bronchi and remodelling of the bronchi. It causes progressive obstruction of the airways and difficulty breathing. Of exacerbations, i.e. a sudden worsening of symptoms, occurring in 80% of patients and often leads to hospitalisation and an excess risk of death in the months and years following – this is the problem the researchers wanted to target.
In two other respiratory diseases, asthma and fibrosis In the lungs, there is an increase in the concentration of fibrocytes, bone marrow stem cells that pass into the blood and colonise the inflamed regions, contributing to the aggravation of these diseases. In the case of asthma, these cells differentiate into smooth muscle cells (myocytes) that increase the contractions of the bronchi. In case of pulmonary fibrosis, fibrocytes differentiate into fibroblasts (tissue support cells) and accentuate fibrosis.
Forest Medical Spirometer Calibration
Spirometry is a breathing or ‘lung function’ test. It’s one of the most common tests people with asthma, or people who are being tested for asthma, are given. Your GP or asthma nurse will ask you to take a deep breath and then breathe out as fast as you can and for as long as you can through a mouthpiece linked to a ‘Spirometer’. You will have to blow a few times so your GP or asthma nurse can get an accurate result.
As with all medical equipment, Spirometers need thorough and comprehensive testing on a regular basis. Failure to adequately test a Spirometer puts it at risk of failure or of false readings being displayed from the equipment, which can have disastrous results.
We undertake thorough Spirometer Calibration to fully test your machines and ensure that they are safe and suitable for use.
Tofauti katika anatomia ya mapafu pekee yaweza kueleza kwa nini mtu mmoja ana uwezekano mkubwa zaidi kuliko mwingine wa kupatwa na ugonjwa wa mapafu usio na utaratibu (COPD). Utafiti huo ulifanywa na timu ya watafiti kutoka Taasisi ya Utafiti ya Chuo Kikuu cha McGill (RI-MUHC) na Chuo Kikuu cha Columbia. Watafiti hao walichunguza picha za CT za wagonjwa zaidi ya 3,000 walio na ugonjwa wa mapafu unaoendelea (COPD) na wasio nao, ambao husababisha uvimbe wa njia za kupumua na kufanya upumuaji uwe mgumu. Karibu asilimia 16 ya watu wana sehemu ya ziada ya njia za hewa katika mapafu, na asilimia 6 wana sehemu inayokosekana, wakati asilimia 4 huonyesha mchanganyiko wa aina tofauti au muundo tofauti. Matokeo ya utafiti huo yamechapishwa kwenye jarida la Proceedings of the National Academy of Sciences. COPD ni ugonjwa wa kawaida unaoathiri bronchi na kuchochea kwa njia ya upasuaji. Husababisha kizuizi cha kuendelea cha njia za kupumua na ugumu wa kupumua. Kwa sababu ya kuongezeka kwa ugonjwa, yaani, Madhara ya ghafla ya dalili, ambayo hutokea kwa asilimia 80 ya wagonjwa na mara nyingi husababisha kulazwa hospitalini na hatari kubwa ya kifo katika miezi na miaka inayofuata, ni tatizo ambalo watafiti walitaka kulenga. Katika magonjwa mengine mawili ya kupumua, asthma na fibrosis, kuna ongezeko la mkusanyiko wa fibrocytes, seli za msingi za mifupa ambayo hupita kwenye damu na kuhamia maeneo yenye uvimbe, na kuchangia kuongezeka kwa magonjwa haya. Katika ugonjwa wa pumu, chembe hizo hutokeza chembe za misuli laini (myocytes) ambazo huongeza kunyonyesha kwa mifupa. Katika kesi ya fibrosis ya mapafu, fibrocytes kutofautisha katika fibroblasts (chembe za msaada tishu) na kusisitiza fibrosis. Forest Medical Spirometer Calibration Spirometry ni kupumua au "ufanyakazi wa mapafu" mtihani. Ni moja ya vipimo vya kawaida watu wenye pumu, au watu ambao ni kupimwa kwa pumu, ni kupewa. Mtaalamu wa afya ya mwili au wa pumu atakuomba upumue kwa kina na kisha upumue kwa haraka iwezekanavyo na kwa muda mrefu iwezekanavyo kupitia mdomo uliounganishwa na spirometer. Ukifanya hivyo, utahitaji kupasua mara kadhaa ili daktari wako wa kawaida au muuguzi wa pumu apate matokeo sahihi. Kama ilivyo na vifaa vyote vya kitiba, Spirometers zinahitaji kupimwa kwa undani na kwa undani kwa ukawaida. Kushindwa kupima Spirometer kwa kutosha huweka hatari ya kushindwa au kusoma bandia kuonyeshwa kutoka kwa vifaa, ambayo inaweza kuwa na matokeo mabaya. Sisi kufanya kikamilifu Spirometer Calibration kikamilifu mtihani mashine yako na kuhakikisha kwamba wao ni salama na yanafaa kwa ajili ya matumizi.