A recent article in the New York Times reports on research that links long-term Proton Pump Inhibitors (PPIs) with a 30% increased risk of bone fractures. According to the article, the long-term use of PPIs may decrease absorption of calcium in the intestines.
PPIs reduce the acidity in the stomach in order to reduce symptoms of heartburn. While this is an effective approach for reducing the burning pain caused by the regurgitation of stomach acid into the esophagus, lowered acidity in the stomach decreases the absorption of some nutrients – including calcium – and increases the chances of getting several types of infection including infections of the digestive tract and lung.
Some forms of calcium do not require stomach acid in order to be absorbed. These forms include calcium citrate and calcium citrate/malate. When taking PPIs or other antacid medicines, it is a good idea to supplement calcium intake with these forms of calcium especially if you are at increased risk of osteoporosis or of fracture.
The only drawback of calcium citrate and calcium citrate/malate is that these forms of calcium are very bulky – capsules usually contain only 150mg of calcium. This means that the usually recommended dosage is 5 to 10 capsules per day.
Ensuring healthy vitamin D status is also very important for calcium absorption.
For more information on addressing osteoporosis, read my previous blog post on osteoporosis.
Other nutrients whose absorption can be decreased by acid lowering medications include magnesium and vitamin B-12.
Richard Malik, ND
Utafiti wa hivi karibuni wa New York Times unaonyesha kuwa matumizi ya dawa ya muda mrefu ya kuzuia protoni (PPI) huongeza hatari ya kuvunjika kwa mifupa kwa asilimia 30. Kulingana na makala hiyo, matumizi ya muda mrefu ya PPIs yanaweza kupunguza kunyonya kwa kalsiamu katika matumbo. PPI hupunguza asidi ya tumbo na kupunguza dalili za maumivu ya moyo. Ingawa hii ni mbinu ya ufanisi ya kupunguza maumivu ya kuchoma inayosababishwa na regurgitation ya asidi ya tumbo katika esophagus, acidity ya chini katika tumbo hupunguza kunyonya kwa baadhi ya virutubisho, ikiwa ni pamoja na kalsiamu, na huongeza uwezekano wa kupata aina kadhaa za maambukizo, ikiwa ni pamoja na maambukizo ya mfumo wa kumeng'enya na mapafu. Aina fulani za kalsiamu hazihitaji asidi ya tumbo ili zinyunywe. Aina hizi ni pamoja na kalsiamu citrate na kalsiamu citrate / malate. Wakati wa kutumia PPIs au dawa nyingine za antiacid, ni wazo nzuri kuongeza ulaji wa kalsiamu na aina hizi za kalsiamu, haswa ikiwa una hatari kubwa ya osteoporosis au kuvunjika. Kosa la calcium citrate na calcium citrate ni kwamba aina hizi za calcium ni kubwa sana - vidonge kwa kawaida vina 150mg tu ya calcium. Kwa kawaida, kipimo cha kawaida kinapendekezwa ni vidonge 5 hadi 10 kwa siku. Kuhakikisha hali nzuri ya vitamini D pia ni muhimu sana kwa kunyonya kalsiamu. Kwa habari zaidi juu ya jinsi ya kukabiliana na osteoporosis, soma chapisho langu la awali la blogi juu ya osteoporosis. Vyakula vingine vinavyoweza kupunguzwa na dawa za kupunguza asidi ni pamoja na magnesiamu na vitamini B-12. Richard Malik, ND