Salvestrols cannot be made in the body. They have to be supplied through our diet and to date, herbalists have identified Salvestrols in many organic fruits, vegetables, and herbs. It is estimated that our modern diet contains 10 – 20% of the Salvestrols that it did 100 years ago.
The Need for A Salvestrol Supplement
Even with a solely organic diet, there is no guarantee of adequate levels, as many modern fruit and vegetable varieties are low in Salvestrol. Differing food-growing locations, food growing methods and whether the food was fully ripe at harvest all have an effect.
Salvestrols are mostly found in the skin, peel or rind of fruit and vegetables and in the modern diet, this is the part of the fruit or vegetable least appealing and often not eaten. Many of the modern varieties of fruit and vegetables have been bred to be less bitter and this has meant that the often bitter salvestrol component has been reduced or removed.
Discovery and Research
The discovery of Salvestrols evolved from the work of research scientist Professor Dan Burke. As a faculty member of Aberdeen University Medical School for nearly 20 years, he specialised in the Cytochrome P450 enzyme system. His research group discovered that an enzyme CYP1B1 was present in diseased cells but absent from healthy tissue.
Discovery in Nature
Initially the pair worked on developing synthetic pharmaceutical products to combat disease. But in 2002 they discovered similarly structured compounds were naturally present in many foods. Professor Potter called this new class of natural compounds Salvestrols.
How Salvestrols Work in Plants
The best way to picture Salvestrols is to understand their role in the plants that produce them. When attacked by pathogens, primarily fungi plants defend themselves with Salvestrols. Where pathogens contain a CYP enzyme, Salvestrols are metabolised by the enzymes and die.
The Potential for Humans
The CYP1B1 enzyme in diseased cells offers the potential to use the plants’ response and make it part of our own defence. Consuming Salvestrol-rich plants lets Salvestrols enter our diseased cells and induce their death through metabolism by CYP1B1.
Are Salvestrols Safe?
Salvestrol is made from organically grown fruit. Mostly they are extracted in high concentrations from tangerine or orange peel and blueberries and mixed with concentrated blackberry and strawberry powder.
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Salvestrols haiwezi kutengenezwa katika mwili. Salvestroli ni muhimu kwa afya ya binadamu na kwa sasa, wataalamu wa mimea wamegundua salvestroli katika matunda mengi ya kikaboni, mboga na mimea. Kwa mfano, inakadiriwa kwamba chakula cha leo kina asilimia 10 hadi 20 ya salvestrole kuliko kile kilichokuwa miaka 100 iliyopita. Hata na lishe ya kikaboni tu, hakuna dhamana ya viwango vya kutosha, kama aina nyingi za matunda na mboga za kisasa ni chini katika Salvestrol. Mahali tofauti pa kukuza chakula, mbinu za kukuza chakula na ikiwa chakula kilikuwa kimekomaa kabisa wakati wa mavuno yote yana athari. Salvestrole hupatikana katika ngozi, ganda au ganda la matunda na mboga, na katika chakula cha kisasa, hii ni sehemu ya matunda au mboga ambayo haipendi na mara nyingi hailewi. Aina nyingi za matunda na mboga za kisasa zimezalishwa kuwa na uchungu mdogo na hii inamaanisha kwamba sehemu ya salvestrol mara nyingi chungu imepunguzwa au kuondolewa. Ugunduzi wa Salvestrol ulijitokeza kutokana na kazi ya mwanasayansi wa utafiti Profesa Dan Burke. Alifanya kazi katika Chuo Kikuu cha Aberdeen kwa miaka 20 na alikuwa mtaalamu wa mfumo wa cytochrome P450 enzyme. Katika utafiti wake, aligundua kwamba enzyme ya CYP1B1 ilikuwa katika chembe za mgonjwa lakini haikuwa katika chembe za mwili. Ugunduzi katika Asili Mwanzoni jozi hiyo ilifanya kazi ya kuendeleza bidhaa za dawa za synthetic kupambana na ugonjwa. Lakini mwaka 2002 waligundua kwamba kemikali hizo zilikuwa zipo katika vyakula vingi. Profesa Potter aliita aina hii mpya ya misombo ya asili Salvestrols. Jinsi Salvestrole Inavyofanya Kazi Katika Mimea Njia bora ya kuelezea Salvestrole ni kuelewa jukumu lake katika mimea inayozalisha. Mimea inayoshambuliwa na vimelea, hasa kuvu, hujilinda kwa kutumia Salvestrols. Ambapo vimelea vina enzyme ya CYP, Salvestrols hubadilishwa na enzymes na kufa. Enzyme ya CYP1B1 katika seli zilizoambukizwa inatoa uwezekano wa kutumia majibu ya mimea na kuifanya kuwa sehemu ya ulinzi wetu wenyewe. Kwa sababu ya matumizi ya mimea yenye salvestrol, salvestrol huingia kwenye seli zetu na kuua kwa njia ya metabolism ya CYP1B1. Je, Salvestroli Ni Salama? Salvestrol hutengenezwa kutokana na matunda yaliyokuzwa kwa njia ya kikaboni. Kwa kawaida hutolewa kwa kiasi kikubwa kutoka kwa ngozi ya mandarini au machungwa na blueberries na kuchanganywa na unga wa blackberry na strawberry. Je, wewe ni mtaalamu wa afya ambaye angependa kupata bidhaa hizi? Kama wewe ni mgonjwa na ungependa kupata bidhaa hizi, kutumia ramani yetu kupata Mtaalamu wako wa ndani.