instruction: provide the number of patients whose diagnoses long title is atherosclerosis of native arteries of the extremities with intermittent claudication and drug route is replace?
response: SELECT COUNT(DISTINCT demographic.subject_id) FROM demographic INNER JOIN diagnoses ON demographic.hadm_id = diagnoses.hadm_id INNER JOIN prescriptions ON demographic.hadm_id = prescriptions.hadm_id WHERE diagnoses.long_title = "Atherosclerosis of native arteries of the extremities with intermittent claudication" AND prescriptions.route = "REPLACE"