instruction: when was patient 004-11043 diagnosed with drug overdose- general - multiple agents ingested for the first time until 2 years ago?
response: SELECT diagnosis.diagnosistime FROM diagnosis WHERE diagnosis.patientunitstayid IN (SELECT patient.patientunitstayid FROM patient WHERE patient.patienthealthsystemstayid IN (SELECT patient.patienthealthsystemstayid FROM patient WHERE patient.uniquepid = '004-11043')) AND diagnosis.diagnosisname = 'drug overdose- general - multiple agents ingested' AND DATETIME(diagnosis.diagnosistime) <= DATETIME(CURRENT_TIME(), '-2 year') ORDER BY diagnosis.diagnosistime LIMIT 1