instruction: when is the first time patient 005-48105 has been prescribed medicine in this hospital encounter?
response: SELECT medication.drugstarttime FROM medication WHERE medication.patientunitstayid IN (SELECT patient.patientunitstayid FROM patient WHERE patient.patienthealthsystemstayid IN (SELECT patient.patienthealthsystemstayid FROM patient WHERE patient.uniquepid = '005-48105' AND patient.hospitaldischargetime IS NULL)) ORDER BY medication.drugstarttime LIMIT 1