When people engage in explicit topic avoidance, they risk offending or hurting others. Using a goals theoretical framework, we examined how goal-relevant message features influenced participants' reactions to hypothetical topic-avoidance messages. Participants in this experiment (N = 536) responded to messages that friends might use to deflect a question about a stressful situation. Five types of messages reflected conventionally relevant interaction goals. Results indicated that message features influenced reactions (e.g., judgments of competence, and emotional and verbal responses) and that messages were generally perceived as more competent if they featured secondary relational and identity goals while simultaneously expressing the desire to avoid the subject. Certain secondary goals (e.g., expressing appreciation for the friend's concern) were especially well received compared with others.


Objective To investigate the effects of salidroside on airway remodeling and NF-κB and TGF-β1 signal transduction pathway in asthmatic mice. Methods Forty female BALB/c mice of clean grade were randomly divided into four groups(n = 10), such as control, egg protein(OVA) asthma, low-, and high-dose salidroside groups. OVA was used to establish the asthmatic mice model, and the left lung tissues of all mice were treated by HE, PAS, and Masson trichrome staining after the last excitation in 24 h. The right lung tissues were detected by enzyme linked immunosorbent assay(ELISA) to observe the expression levels of IL-4, IL-5, and IL-13 in bronchoalveolar lavage fluid(BALF), by RT-PCR to investigate the expression level of TGF-β1 mRNA, and by Western blotting to detect the expression levels of TGF-β1 and NF-κB p65 proteins. Results Compared with the control group, the inflammatory cell counts and the expression levels of IL-4, IL-5, and IL-13 in asthmatic model group were increased. The expression levels of TGF-β1 mRNA and NF-κB protein from lung tissues were significantly higher than those in the control group(P 0.01). Compared with the asthma model group, the inflammatory cell counts, the expression levels of IL-4, IL-5, IL-13 in BALF, TGF-β1 mRNA, and NF-κB of p65 protein were significantly decreased in the salidroside intervention groups, with significant differences(P 0.01). But for indexes mentioned above, there were no statistical significances between the two different treatment groups(P 0.05). Conclusion Salidroside might inhibit the development of airway remodeling in asthmatic mice, and the mechanism might be partly achieved through the inhibition of NF-κB/TGF-β1 signal transduction pathway.


Empirical estimates of fuel demand changes to price variation are based on historical consumption and prices, and can be applied as a single point estimate to a wide range of price movements. However, if fuel prices are set outside the boundaries of historical changes, policymakers may be concerned as to the validity of the empirically assessed price elasticity. We have developed a transport model to provide a techno-economic estimate of the price elasticity of fuel demand. It incorporates consumers' choices as a result of several factors, including fuel substitutes, available transport modes, income, value of time and magnitude of price change.


Abstract : The poly--glutamic acid (PGA) capsule produced by Bacillus anthracis is composed solely of D isomer glutamic acid while other Bacillus species produce mixed D, L PGA polymers. To see if the exclusive use of the D isomer confers an advantage against the host immune system, we compared the responses of human innate immune cells to Ba capsule, a predominantly D isomer PGA from B. subtilis subsp. chungkookjang (ch-k-j), and a predominantly L isomer PGA from B. licheniformis (PLGA). As the level of D isomer decreased, cytokine release by differentiating monocytes increased and diversified. Ba capsule elicited only IL-8 and IL-6, while ch-k-j elicited larger amounts of IL-8 and IL-6 plus IL-10 and TNF. PLGA elicited even more IL-8, IL-6, IL-10, and TNF plus IL-1. Similarly, Ba capsule elicited only IL-8 from immature dendritic cells (iDCs), while ch-k-j elicited IL-8 and IL-6, and PLGA elicited IL-6, IL-12p70, IL-10, IL-1, and TNF . When we assessed the PGAs as DC maturation factors, only PLGA induced increased surface expression of CD83 and CCR7 and CCR7 dependent chemotaxis. In a TLR2 assay, we found that ch-k-j and PLGA were both more effective agonists than Ba capsule. Further experiments indicated that ch-k-j is recognized by a TLR2/6 dimer while PLGA and Ba capsule are also recognized by TLR4. We conclude that the exclusive use of D isomer in its capsule provides B. anthracis with an advantage against the host immune system by greatly reducing its recognition by TLRs, thereby blunting the effectiveness of the immune response.


Background: A transverse vaginal septum is a rare congenital uterovaginal anomaly that may be diagnosed for
 the first time during labor with a frequency of 1 in 70,000 females. A 20 years old primigravida with a postterm
 pregnancy whose diagnosis was only made during labor following digital vaginal and speculum examination.
 On examination, she was diagnosed as having a transverse vaginal septum with a pinpoint septal opening. The
 emergency caesarean section, followed by dilatation of the septum, was performed.
Result: The post-operative event was smooth.
Conclusion: To avoid obstructed labor and injuries to the mother and new-born prophylactic caesarean section
 is recommended in patients presenting with a transverse vaginal septum in labor, especially in women who have
 conceived after a long period of infertility.


Emerging topic detection from microblogs has developed into an attractive task because events usually break on social channels. However, due to the features of high noise, short length, fast arriving rate and irregular writing style of microblogs, it has been proven to be a challenge to detect emerging topics from microblog streams early and accurately in a scalable way. Several approaches have been proposed to tackle this problem and have achieved sound performance in some aspects. However, from the point of novelty and scalability, there is still considerable space for improvement. Inspired by the consideration, we propose an emerging topic detection framework based on emerging pattern mining. Via encoding the term novelty into an efficient high utility itemset mining (HUIM) algorithm, a group of emerging patterns which are concise and interpretive representations of topics can be first detected, decreasing the computational cost of the clustering part.


PURPOSE: An epoxysilane coupling agent and vinylsilane coupling agent are added to a thermosetting resin composition for laminate containing 1,2-polybutadiene to improve the adhesion to copper foil and glass cloth. CONSTITUTION: For example, to a varnish obtained by dissolving a thermosetting resin composition for laminate, which contains 1,2-polybutadiene, in a solvent are added 0.5W2.0 parts, per 100pts.wt. of the resin, of epoxysilane coupling and vinylsilane coupling agent respectively. The base material is impregnated with the resulting composition, dried by removing the solvent to give prepregs, which are laminated with copper foil to produce laminated products. USE: The products show high peeling strength. COPYRIGHT: (C)1980,JPO&Japio


A simple method for quantitative determination of N-nitrosodimethylamine was established. The sample containing N-nitrosodimethylamine was passed through the columns of cationand anion-exchanger resins and of active carbon. The effluent was steam distilled under alkaline condition and the distillate was irradiated with UV-light to decompose N nitrosodimethylamine to nitrous acid and dimethylamine, and then the nitrous acid was colorimetrically measured. By using the above procedure, it was found that when the cells of Escherichia coli were incubated with dimethylamine and nitrite at neutral pH, N-nitrosodimethylamine was produced in proportion to the time of incubation and the amount of the cells used. However, N-nitrosodimethylamine was not produced with the boiled cells of E. coli or without the cells. This clearly indicates that N-nitrosodimethylamine is produced from dimethylamine and nitrite at neutral pH by the enzyme action of E. coli. (Received February 19, 1976)


Displaying both invasive and angiogenic tumor growth, glioblastoma (GBM) is characterized as the most aggressive primary adult brain tumor. And while a number of molecules discerning these growth modalities have been described, the mechanisms driving the pathological growth remain an enigma. Among the most clinically relevant, and perhaps also the most cryptic, is signaling generated by activation of the epidermal growth factor receptor (EGFR) tyrosine kinase. EGFR gene amplification is observed in upwards of 40% of GBM biopsies, and genetic aberration to EGFR at large has been described to occur in excess of 60%. Our lab has developed a clinically relevant in vivo model in which we are able to accurately study EGFR signaling in human GBM. We previously reported that wild-type EGFR amplification and activation promotes invasion and development of GBM independent of angiogenesis. Importantly, detected in half of GBMs harboring EGFR amplification, the most prominent EGFR mutation arises upon deletion of exons 2 through 7 to generate the constitutively active truncation mutant EGFRvIII. Expression analysis in combination with signaling complex immunocapture mass spectrometry motivated our hypothesis that EGFRvIII-mediated signaling is divergent from that of its wild-type counterpart. To investigate this, we performed the following animal experiments in accordance with The Norwegian Animal Research Authority's regulations for animal research. We implanted patient GBM tumor cells stably overexpressing EGFRvIII or oncogenic c-Src into the brains of immunodeficient rats. Compared with corresponding xenograft control tumors, those overexpressing EGFRvIII or oncogenic c-Src were substantially more aggressive. In addition, the tumors displayed increased contrast enhancement on MRI, enhanced histological features of angiogenesis, and upregulation of molecular markers for tumor angiogenesis on western blot. Patient GBM cells stably overexpressing wild-type EGFR, meanwhile, failed to promote angiogenesis and instead contributed to a more infiltrative phenotype consistent with our previous findings. Furthermore, tumors overexpressing EGFRvIII and simultaneously depleted of c-Src using specific shRNA were less aggressive and non-angiogenic. We hereby report evidence that EGFRvIII-driven c-Src protein upreguation and subsequent activation intensifies the malignancy of human GBM by facilitating aggressive tumor growth and promoting vascular endothelial growth factor (VEGF) mediated angiogenesis. In conclusion, our results suggest that the EGFRvIII-SRC-VEGF pathway represents a meaningful target in the therapeutic intervention of primary GBM.


ABSTRACT As one of the financial instruments, the Bank plays a very important role, because the supervision of banking activities is increasingly being improved. However, with the current monetary crisis in Indonesia and the continuing turmoil of the political situation, it has brought the Indonesian banking industry into a really difficult situation. Considering the condition of this National Bank, the government decided to liquidate private banks with low performance. In the framework of national banking restructuring, the government also proposed to merge some national private banks and state-owned banks. This merger step has a strategic goal, namely to form a larger merged bank, strengthening the capital structure, has a comparative advantage as well as a stronger competitiveness in this globalization. The purpose of this study is to know the effect of merger on the level of profitability at Bank Danamon. The type of research used in this study is descriptive research while for data collection authors use secondary data. The population of this study include 9 Bank Take Over and samples taken as many as two banks, using purposive sampling technique. The analytical model used is, the analysis using the financial ratios of Gross Profit Margin, Net Profit Margin, Return On Investment, and return On eqiuty and Test T. The results show that: (1) Bank Danamon Tbk is a merged bank between Bank Danamon With Bank Take Over (Tiara Asia Bank, Risjad Salim Bank, Duta Bank, Tamara Bank, Bank Nusa Nasional, Rama Bank, Bank Jaya and Bank Pos Nusantara). (2) The implementation of the merger has a positive impact on the level of profitability at Bank Danamon. (3) There is a significant difference between profitability before and after merger, it can be seen from result of t test which show that tcount (4,039) is bigger than ttable (3,182). Keywords: Merger, Profitability


Objectives:To study for influencing factors on choosing early abortive methods.Methods: 196 early pregnant women were surveyed with questionnaire.They may choose one kind of methods ,and they were divided into two groups:medical abortion and surgical abortion.The reasons for choice were analysed.Results: When women had their choice between the two,then prefer medical abortion than surgical abortion.The young and unmarried and non parous women choose medical abortion much more than those elder,married and parous ones.Conclusion: Women take a one sided approach to abortive methods.they will consider many problems when they confront choice.Doctors should provide for women as far as possible consultation and suggestion.


The isomeric triazoles 4-methyl-5-phenyl-1-phthalimido-1,2,3-triazole (1) and 5-methyl-4-phenyl-1-phthalimido-1,2,3-triazole (2) have been pyrolysed in the vapour phase at 400–500°, and give the same products, which involve the antiaromatic 1H-azirine derivative, 2-methyl-3-phenyl-1-phthalimido-1H-azirine (3), as a common intermediate.


OBJECTIVE To explore the epidemiological characteristics of postoperative nosocomial infections in the femoral neck fracture patients undergoing hip arthroplasty and analyze the risk factors so as to provide guidance for prevention of infections.METHODS A total of 1 000 femoral neck fracture patients who underwent the hip arthroplasty from Jan 2009 to Oct 2014 were enrolled in the study,the clinical data of the patients were retrospectively analyzed,the incidence of nosocomial infections and infection sites were recorded,and the risk factors for the nosocomial infections were observed.The statistical analysis was performed with the use of SPSS16.0software,and the multivariate logistic regression analysis was carried out.RESULTS The nosocomial infections occurred in 36 patients with the incidence rate of 3.6%,of whom 41.7%(15cases)had the surgical incision infections.Totally58 strains of pathogens have been cultured,among which the gram-negative bacteria were dominant,accounting for 75.9%(44strains).The logistic regression analysis indicated that the length of hospital stay,types of surgery,types of antibiotics,and catheter indwelling time were the independent risk factors for the postoperative nosocomial infections in the patients undergoing hip arthroplasty(P0.05).CONCLUSIONThe gram-negative bacteria are the predominant pathogens causing the postoperative nosocomial infections in the femoral neck fracture patients undergoing hip arthroplasty.The independent risk factors for the postoperative nosocomial infections in the patients undergoing hip arthroplasty include the length of hospital stay,types of surgery,types of antibiotics,and catheter indwelling time.


A 36-year-old woman with effort dyspnea for 2 years, venous congestion of the left arm for 6 months and who did not have a history of a thoracic trauma was hospitalized. Posterior bilateral dislocation of the sternoclavicular joints and compression of the brachiocephalic vein were diagnosed and conformed by computed tomography (CT). The joint could not be reduced because of the old dislocation and destruction of the joint in the operation. The heads of the clavicles were resected and the vein compression was eliminated. Six weeks later, venous congestion disappeared and the brachiocephalic vein was patent.


The Sahel of Tunisia is part of the arid zone that extends from Morocco to Afghanistan. People in this region profess the religion of Islam. Their views on the links between divine power, human actions, and rain are based on the Quran and are expressed in the rain prayers (salat a1-isrisqa') prescribed by the Prophet and therefore common to all of them. This article refers to North Africa, centering on the village of Sidi Ameur in the Sahel of Tunisia.


149 Background: ASCO recommends CSFs such as pegfilgrastim for dose dense doxorubicin cyclophosphamide paclitaxel (ddACT) in breast cancer. It is unclear whether dose dense paclitaxel requires pegfilgrastim, and some community oncologists use pegfilgrastim selectively with the dose dense paclitaxel portion of ddACT. We reviewed the results of pegfilgrastim use based on physician preference within a single breast oncology community-based practice.

METHODS
This is a single-center, single-practice retrospective cohort study of adjuvant ddACT for breast cancer patients identified from the pharmacy database between 1/2010 and 6/2014. Patient demographics, stage, chemotherapy and pegfilgrastim use, chemotherapy delays, febrile neutropenic (FN) events, and pain records including narcotic use were collected from patient charts. Patients receiving pegfilgrastim routinely at cycle 1 were compared to those within the practice given pegfilgrastim selectively for ANC < 1.5 on day of treatment or nadir ANC < 1.0 during the preceding cycle. Differences between groups were analyzed using the Mann-Whitney test, with significance at the p < 0.05 level.

RESULTS
The two groups were balanced with regard to age and number of cycles. There were no significant differences in cycle delay, and FN. Routine pegfilgrastim resulted in more bone pain and higher cost.

CONCLUSIONS
The selective use of pegfilgrastim during the paclitaxel portion of ddACT did not result in chemotherapy delay, more infections or FN. It did decrease painful myalgia and arthralgias, and dramatically lowered treatment cost. These retrospective data, although limited by participant number, question the need for the routine use of pegfilgrastim for the paclitaxel portion of ddACT and require prospective validation. [Table: see text].


The present study was conducted to determine the allelopathic effect of wheat straw on three weed species, viz. Chenopodium album L., Boerhavia diffusa L. and Parthenium hysterophorus L. Straw treatments linearly decreased the germination and the length of roots and shoots of the test weeds relative to controls. At the higher concentrations of wheat straw leachates, seed germination was least affected in Parthenium hysterophorus and most affected in Boerhavia diffusa under burned and unburned straw treatments, whereas, at lower concentrations (25%) of the burned straw treatment, it remained similar to the water control. Seedling growth was less affected under lower concentrations. Thus, straw management practices should be considered when developing an integrated weed management program.


Objective To study the expression of ma tr ix metalloproteinase-2(MMP-2)and tissue inhibitor of metalloproteinase-2(T IMP-2)in endometriosis (EMs) and to discuss the role in the occurrence and dev elopment of EMs. Methods Immunohistochemistry S-P meth od was employed to detect the expression of MMP-2 and TIMP-2 in the ectopic en dometrium of the patients(50 cases), the eutopic endometrium of the patients w ith endometriosis(20 cases). Results The positive exp ressions of MMP-2 in the ectopic endometrium was 41 in 50 cases of the patients with endometriosis, the positive expression rate was 82%. But the expressions o f MMP-2 in the eutopic endometrium of 2 in 20 cases were positive; the positive expression rate was 10%. There was extremely difference between the two groups (P 0.01). The expression of MMP-2 was up-regulated with the increasing cl inical stage of endometriosis, but the expression of TIMP-1 was down-regulated with the increasing clinical stage. The difference has statistic significance i n MMP-2 and TIMP-2(P0.05). Conclusions The inc reasing expression of MMP-2 and the decreasing expression of TIMP-2 may be key role in occurrence and development of EMs, and the unbalanced expression degree could act as an index to evaluate the progress and prognosis in endometriosis.


The polycondensation of methyl α-D-mannopyranoside (I) with 1,x-bis(2-formylphenoxy)alkanes (II) using various acid catalysts leads to the formation of macrocyclic compounds [1+1] and [2+2] and linear copolymer. NMR and ESI-MS studies demonstrated the evidence of structure of macrocyclic compounds. The structure of dialdehyde, the nature of the catalyst, and in particular, the molar ratio of catalyst to dialdehyde, show a very pronounced effects on yield of the resulting macrocycles.


This research conducts tests to measure the quality of e-government websites of five Asian countries via web diagnostic tools online. We propose a methodology for determining and evaluating the best e-government website based on many criteria of website quality, consisting of linear weightage model (LWM), analytical hierarchy process (AHP), fuzzy analytical hierarchy process (FAHP), and one new hybrid model (NHM). This NHM has been implemented using combination FAHP and LWM to generate the weights for the criteria which are better and more fairly preferred. The results of this study confirmed that most Asian websites are neglecting in performance and quality criteria. By applying the hybrid model approach it has resulted in significant acceleration of implementation, raised the overall effectiveness and enabled more efficient procedure. To compare the ranking methods, a combination of Friedman's test and Dunn's multiple comparison procedure is adopted. When applied to the methods presented here, these tests indicate that AHP, FAHP, and Hybrid method methods perform better than LWM.


Most existing studies on selling strategies in online auctions do not distinguish auction heterogeneity when providing operational selling recommendations. They also tend to assume single objective for sellers. In this study, we incorporate seller and product heterogeneity into our analytical framework and implement data mining analysis in four auction segments. We use classification and regression tree (CART) to identify the critical factors along with their sequences for auction success and prices. We find different determinants for auction success and ending prices in these four auction segments. The classification and regression trees provide operational choices for sellers to build the most effective selling strategies. We propose that, by using expected auction prices with the classification and regression trees, sellers can integrate auction success and prices as multiple objectives in their selling strategies. Overall, this study contributes to the literature by providing an innovative methodology for effective selling recommendations, which can potentially lead to significant and smooth growth of the online auction market.


In accordance with a method according to the invention for operating an elevator, a travelling mode is prevented if it is established that an elevator load (L) exceeds a limit value. During normal operation, the limit value is equal to a basic limit value (G1). If it is established that a special situation, in particular an evacuation situation or a peak traffic situation, is present, the system is switched over to a special situation mode. In the special situation mode, the limit value is equal to a second limit value (G2), which is higher than the basic limit value (G1).


Purpose

The purpose of this study is to evaluate how accurately a 3D printer could manufacture basic porous models. Geoscience research is evolving toward numerical prediction of porous rock properties, but laboratory tests are still considered a standard practice. 3D printing digital designs of porous models (proxies) is a way to bridge the gap between these two realms of inquiry.

Design/methodology/approach

Digital designs of simple porous models have been 3D-printed on an inkjet-style (polyjet) 3D printer. Porosity and pore-throat size distribution of proxies have been measured with helium porosimetry, mercury porosimetry and computed tomography (CT) image analysis. Laboratory results on proxies have been compared with properties calculated on digital designs and CT images.

Findings

Bulk volume of proxies was by 0.6-6.7 per cent lower than digital designs. 3D-printed porosity increased from 0.2 to 1.9 per cent compared to digital designs (0-1.3 per cent). 3D-printed pore throats were thinner than designed by 10-31 per cent.

Research limitations/implications

Incomplete removal of support material from pores yielded inaccurate property measurements. The external envelope of proxies has been 3D-printed at higher accuracy than pores.

Practical implications

Characterization of these simple models improves understanding of how more complex rock models can be 3D-printed accurately and how both destructive (mercury porosimetry) and non-destructive (CT and helium porosimetry) methods can be used to characterize porous models.

Originality/value

Validation of 3D-printed porous models using a suite of destructive and non-destructive methods is novel.


Purpose- The aim of this study is to assess the factors limiting the full-scale adoption of process and product innovation by construction organizations in Nigeria with a view to suggesting probable ways of eliminating them
Design/Methodology- The study adopted a questionnaire survey approach in which data were collected from the participants using simple random sampling techniques in the study area. Frequency, percentage, mean item score, and Independent sample T-test was used to analyze the gathered data.
Findings- It was found that poor funding, poor support and commitment from management, fragmented nature of the construction business, poor coordination and communication among project participants, lack of qualified and experienced staff and the unwillingness of clients to pay for innovative ideas are the factors limiting innovations in construction.
Practical Implications- The outcome of this study will give the management of construction-based organizations an insight into the major limiting factors of innovation, so that appropriate strategies for overcoming them could be developed at the conception stage of construction projects.


This research work, was carried out, to find the importance of computerized analysis on spoilage of plantain, before harvest and carriage to market in Osun State, Nigeria. 3,600 open questionnaires were distributed to the 4 Local Governments, namely: (Ife East, Ife South, Ife Central, and Ife North), local government areas in Osun State, Nigeria. Out of which 900 was used for farmers, in each local government. A total of 36 locations were sampled in all the four local governments, out of which 100 questionnaires were used in each location. It was gathered that above 70% of the farmers supported, the importance of computerized analysis on spoilage of plantain, before harvest and carriage to market in Osun State, Nigeria, while less than 30% of the people could not even understand whether there was the needy, on the importance of computerized analysis on spoilage of plantain, before harvest and carriage to market in Osun State, Nigeria, or not. The results from the questionnaires when using Pearson one-tailed correlation coefficient, however revealed that there was no significant difference from all the farmers visited and sampled, (p < 0. 05), table 5. This shows a strong positive correlation, which implying that, the importance of computerized analysis on spoilage of plantain, before harvest and carriage to market in Osun State, Nigeria, was strongly influenced and enhanced farmer's support, and had therefore, made this research work to become a reality, (p < 0. 05), table 5. The reasons may be due to the fact that in Nigeria, as one of the major staple food, plantain products is not only commonly used for making DODO (fried ripe pulp), IPEKERE well known as chip (fried un-ripped pulp), and as plantain flour but there is a great potential for the processing of plantain. It could however be processed to food / foodstuffs, such as breakfast cereals, baby food (soy-musa), flour, chips and snacks food. Also, industrial product of plantain processing includes: wine / beer, syrups, vinegar, biscuit, among others. Pie Chart was used to depict the summary data of each of the local government areas sampled.


Toll-like receptors (TLRs) are membrane-spanning receptors that play a key role in the innate immune system.. They play an important role in providing innate immunity. TLR1 is one such protein that belongs to this family .It recognizes pathogen-associated molecular pattern and is specific for gram-positive bacteria. TLR1 dimerizes with TLR2 and identifies a mycobacterial lipoprotein .This interaction and recognition is considered to be a key step in the invasion of Mycobacterium based infections like tuberculosis. The protein structure for TLR1 has not yet been predicted, either theoretically or experimentally. This gave us scope for building a model structure for Human Toll like Receptor 1 using multiple templates and MODELLER 9v7 .


Objective:To investigate the effect of ghrelin administration on the severity of acute lung injury and on the production of proinflammatory cytokines and Substance P (SP) in rats with acute pancreatitis (AP). Methods:AP was induced in rats by sodium taurocholate injection through pancreaticobiliary duct. Ghrelin 20 nmol/kg was given before and after the treatment. Tumor necrosis factor-&agr;, interleukin-1&bgr;, and -6 levels in the serum were measured using the radioimmunoassay method. Morphological signs of lung injury, pulmonary water content, microvascular permeability, and myeloperoxidase activity were measured. Meanwhile, the determination of pulmonary SP mRNA level and its expression were performed by reverse transcriptase polymerase chain reaction and immunohistochemistry. Results:The serum proinflammatory cytokines, pulmonary water content, microvascular permeability, and myeloperoxidase activity were increased, and morphological damages were observed in the lung of AP rats. SP mRNA level and its expression were significantly higher in sham-operated rats (P < 0.05). Morphological damages were attenuated and serum cytokines and pulmonary parameters were reduced by pre- and posttreatment with ghrelin. Pulmonary SP expression was also significantly down-regulated by ghrelin (P < 0.05). Conclusions:Ghrelin attenuates the severity of acute lung injury induced by AP. The reduction of neutrophil sequestration, limitation of proinflammatory cytokines release, and inhibition of pulmonary SP expression may be the mechanisms involved in the therapeutic effect of ghrelin.


There was widespread occurrence of Fusarium head blight and the mycotoxin deoxynivalenol (DON) on barley produced in Minnesota, North Dakota, and South Dakota during 1993. To study the fate of Fusa...


This paper investigates the instability of capitalism defined as a condition under which capitalism creates inflation, unemployment, and business cycles. Great economists such as Marx, Veblen, and Schumpeter have examined this problem, concluding that capitalist instability will transform capitalism. A model is developed in this paper to investigate instability, and the finding is that the basic cause behind instability is the conflict on income share: wages and profits. The fluctua tions in the share of profits create inflation, unemployment, and business cycles. This generalization has been verified by using data from the American economy for the 1970s, 1980s, and the 1990s. Over this period, the paper concludes, when the profit share is high, moderate inflation and employment were generated, and when profit share is low, inflation, unemployment, and business cycles have ap peared.


In this study, a spring–mass physical model is proposed to study the complex band structure of a one-dimensional parity-time (PT)-symmetric local resonant phononic crystal. By solving the kinetic equations, the analytical solutions of the dispersion relation and effective mass are obtained. As is known, the infinite effective mass would appear at the resonant frequency in a Hermitian system without any gain or loss. Once the balanced gain and loss are added to form a PT-symmetric system, the infinite effective mass would become finite, and the exceptional points can be observed in the subwavelength realm. With the increase in gain and loss, exceptional points would coalesce and form a higher order one. The numerical simulations in a practical structure agree well with the analytical analysis. In addition, the simulated transmission/reflection spectrum and field distribution clearly demonstrate the anisotropic transmission resonances. Our investigation enriches the physical connotation of local resonant phononic crystals in non-Hermitian systems.


Urgency of the research. In conditions of negative changes in the external environment, anti-crisis stability plays a significant role in ensuring long-term effective business activity. Target setting. Anticrisis firmness is a complex system that is quite difficult to formalize. This requires the use of a systematic approach of assessing the crisis-proof sustainability of the enterprise, which will provide entrepreneurs with effective tools to ensure the stability of operations in crisis conditions. Actual scientific researches and issues analysis. Apart from the attention of those and other scientists, the problem of assessing the anti-crisis stability of the enterprise remains in the competitive environment. Uninvestigated parts of general matters defining. Theoretical-methodological and practical principles of anti-crisis activity of the enterprise are devoted to the work of many leading researchers: Gradova A. P., Gryaznova A. G., Ligonenko L. O., Tereshchenko O. O., Shershnyova Z. Y. The issues of ensuring the stability of enterprises were reflected in the works: Boyko A. V., Broilo O. V., Grigoryan K. S., Yachmenova V. M. The research objective. Applying a systematic approach of assessing the anti-crisis strength of the company in order to create a qualitative analytical and practical basis for ensuring the anti-crisis sustainability of the company in the long run. The statement of basic materials. The essence of the systematic approach of assessing the anti-crisis stability of the company in a competitive environment is revealed, which is taking into account the existing possibilities of providing external anti-crisis stability and anti-crisis stability of the functional subsystems of the enterprise with simultaneous improvement of the competitive position, that allows to provide models of enterprises according to the resulting index of competitive position and the level of systemic provision of anti-crisis stability. Enterprises. Conclusions. The resulting indicator of a competitive position in terms of providing anti-crisis stability of the enterprise allows comparative analysis in time and space, when it can reflect the actual level of competitive position in terms of providing anti-crisis stability of the enterprise.


There have been many advances in the management of maxillofacial infections. New classes of antimicrobial agents, non-invasive imaging techniques, improved culturing methods, and clearer understandings of the normal and pathologic functioning of the immune system are just some of the changes that have occurred. These and other technological advances have enhanced dramatically our ability to diagnose and treat these infections rapidly and accurately. As a result, the incidence of serious morbidity and mortality from odontogenic infections has fallen significantly over the years. It should be noted, however, that vigilance regarding research and technologic changes must be maintained. Just as we have made many advances in the management of these infections, an equal number of new and serious issues have arisen to test our resolve. For every new drug we formulate, resistance develops to an older and often used one. For every organism that we eradicate, another one suddenly emerges to take its place. Therefore, thorough understanding of newer infections is required for the survival of mankind.


According to construction practice of lifting the Electric Time Tower of Wenzhou International Meeting and Exhibition Center,authors state some aspects of towering mast tower structures such as plan selection,working process and lifting construction technologies and so on.


The method for surface coating of potassium titanate whiskers (PTW) with inorganic SiO_2 was studied by using ethyl acetate as homogeneous precipitation agent. The coated layer on the surface of PTW were characterized and analyzed with SEM, FTIR, XRD, and EDX. Zeta potential measurement was used to compare the surface electric properties of coated PTW and pure SiO_2.The results showed that the surface of PTW was coated with inorganic SiO_2 layer and the surface properties are near to pure SiO_2 particles, which would help to further modification of PTW.


Implementing Enterprise Resource Planning ERP projects in many organizations are faced with failure concept in recent years. Researchers focused to implement ERP projects successfully by proposing the success model. However, through these attentions to get ERP benefits, the ERP failure measurement model is required. Therefore, the aim of this study is to develop the instruments for ERP post-implementation failure measurement model. To achieve this outcome, the study firstly evaluates the suitability of Technology-Organization-Environment framework for the proposed conceptual model. Constructs were used for this model included two formative and six reflective constructs. A questionnaire was developed to test the validity and reliability of instrument items. A survey was conducted among Iranian industries to collect data and data analyzed by Smart PLS software. The results indicated that all instruments items included 37 critical risk factors CRFs as measurement were acceptable for the ERP post-implementation failure model.


Despite the fact that there are rapid growth of mergers and acquisitions in both Western and Asian countries, little has been written about the mergers and acquisitions in Asia. Even if there are any on Asian mergers and acquisitions, most studies that have been done focused on the effect of mergers and acquisitions of that particular merged firm and also the post performance of the same, not many studies have been concentrated on the factors of the said transactions. This paper provides a research on the factors to the growth of mergers in Malaysia through questionnaires which have been distributed among selected groups involved in mergers and acquisitions transactions. The objective of this research is to gather the information on factors of mergers and acquisitions and further investigate on whether legal control plays a role in mergers and acquisitions transactions. Research evidence shows that legal control plays a role on mergers and acquisitions transactions but it has not been regarded as the most important factor.


The invention discloses an aluminum cable steel reinforced cutting wrench. The aluminum cable steel reinforced cutting wrench comprises a wrench handle and a wrench head; an annular wheel is rotatably arranged on the wrench head, and a plurality of sawteeth are arranged on the inner side of the annular wheel; the multiple sawteeth are circumferentially and evenly arranged along the inner side of the annular wheel, and a rotating handle is arranged on the wrench handle; and the rotating handle is in transmission connection with the annular wheel. By the adoption of the technical scheme, one person can rapidly finish cable cutting on the ground, so that the cable cutting time and the power failure time are greatly shortened; meanwhile, the risk of accidental saw breaking caused when a common steel saw cuts a cable is avoided, benefits are created for the enterprise and the society, and the aims of downsizing payrolls and increasing efficiency are achieved; and the construction technology is improved, the pressure joint time of a cable strained tube is reduced, and expenditures for the manual cost are directly reduced.


C_: itizenship education is the aged great-uncle at a family gathering. Everyone treats him with respect and some are genuinely fond of him, but few want to sit next to him at the dinner table. He used to command a lot of attention, but that was before the family grew up. Today some of the younger cousins are beginning to realize that he still has a lot to say, if only they will take the time to listen. The respect accorded citizenship edu cation can be traced to the early days of public education in America. Thomas Jef ferson, in supporting the establishment of schools at public expense, argued that students should learn to read, write, and figure so that they would be ready for the responsibilities of citizenship. In those days school subjects were considered mainly as means to the end of good citi zenship. Gradually the subjects taught in schools came to be ends in themselves, however, and the attention given to citi zenship education declined accordingly. Though it continues to be respected in principle, citizenship education receives less and less emphasis in practice. (Thus, contrary to what many may think, the back-to-basics movement continues an es tablished trend: It places emphasis on teaching the three Rs instead of using them to develop the first R, responsible citizenship.) Much of the attention given to citizen ship education is no more than lip service. In Texas, for example, numerous state laws and policies proclaim the importance of good citizenship as a goal of public education, but the practical incentives promote teaching of the three Rs rather than citizenship education. Boosting scores on competency tests has become an all-consuming goal of schools throughout the state, while citizenship education languishes. Accreditation data filed by 54 school districts in central Texas showed that in only three did the responsible of ficials consider citizenship a priority for improvement. In contrast, 33 districts identified reading, 27 identified mathe matics, and 15 identified English/lan guage arts as priorities. ' The situation in other states appears to be similar. Citizenship content may be considered superficially when texts are evaluated for adoption, and state policies usually call for the infusion of citizenship education (along with a potpourri of career education, multicultural education, crime and drug abuse education, etc.). But there is relatively little encourage ment, and even less real support, for teachers who take citizenship education seriously.


Campus culture and its civilization not only have their own characteristics on the conditions of appearance,the evidence of existence,the form of variability and the attribution of value,but also have their own relativity on the entity and change.To clarify the dialectic relation of campus culture and its civilization will help us understand the development theory of campus culture and construct an effective model of strengthening campus culture.


We propose a new, but relatively short, experimental program at HERA to use the existing HERA‐B detector to run in the 920 GeV proton beam to study the production and decay properties of centrally‐produced glueballs and hybrid mesons (the latter produced in P omeron‐R eggeon collisions). A search for о dderon‐Exchange will also be carried out by measuring isolated centrally‐produced I=0, C=−1 states such as ω0. A Level‐1 trigger based on rapidity‐gap vetoes at small and large angles outside the spectrometer aperture will efficiently select these events. We show the properties of such events extracted offline from > 70⋅106 triggered events, corresponding to about 5 minutes of data taking with such a rapidity‐gap trigger. For example, a 100 hour data‐taking run in the manner described herein will already yield a factor of 1000 times more data than displayed in this Proposal. Such a data sample would allow fundamental contributions to be made to a number of important fields.The 100‐hour run corresponds to ab...


Nabokov claims that the sole goal of the translation is to replace one language with equal textual material, and he stresses that the translation must be highly consistent with the original in terms of content, language forms, sentence structure, etc. Nabokov carries out the principle of literal translation in the Anglo-Russian, Russian-English translation works, especially in the English translation work Eugene Onegin. Absolutely faithful translation is extremely difficult for the translator, which is not only the restriction of translation, but also the fundamental problem of translation activity. Hence, the restriction of translation activity, in the aspects of vocabulary, rhythm and grammar, is analyzed based on Nabokov's Anglo-Russian translation works in this paper. Restriction and creation of translation activities are dualism factors without absoluteness, but Nabokov claims that a translator should not impose his own personal style upon translation, and translation activity is not the translator's personal creation activity. Nabokov's positive attitude toward translation activity restriction and negative attitude toward its creation are Nabokov's most important translation strategies. Moreover, the essential reasons for Nabokov to form his translation strategy are his life experiences, that is, his exile background and his Russian complex.


We present a Lipschitz continuous Transformer, called LipsFormer, to pursue training stability both theoretically and empirically for Transformer-based models. In contrast to previous practical tricks that address training instability by learning rate warmup, layer normalization, attention formulation, and weight initialization, we show that Lipschitz continuity is a more essential property to ensure training stability. In LipsFormer, we replace unstable Transformer component modules with Lipschitz continuous counterparts: CenterNorm instead of LayerNorm, spectral initialization instead of Xavier initialization, scaled cosine similarity attention instead of dot-product attention, and weighted residual shortcut. We prove that these introduced modules are Lipschitz continuous and derive an upper bound on the Lipschitz constant of LipsFormer. Our experiments show that LipsFormer allows stable training of deep Transformer architectures without the need of careful learning rate tuning such as warmup, yielding a faster convergence and better generalization. As a result, on the ImageNet 1K dataset, LipsFormer-Swin-Tiny based on Swin Transformer training for 300 epochs can obtain 82.7\% without any learning rate warmup. Moreover, LipsFormer-CSwin-Tiny, based on CSwin, training for 300 epochs achieves a top-1 accuracy of 83.5\% with 4.7G FLOPs and 24M parameters. The code will be released at \url{https://github.com/IDEA-Research/LipsFormer}.


It is assumed that the overall combination of the positioning of speech articulators such as the tongue, jaws and lips differs per language, which is commonly referred to as articulatory settings. Previous studies involving analytic listening, as well as acoustic analyses and those based on modern scanning techniques that can visualize the vocal tract claim to have found evidence for the existence of articulatory settings; yet, thus far none of these seems to have found unambiguous measurable evidence for language specific settings. The present study attempts to acoustically measure differences between the settings of English and Dutch under optimal conditions, based on within-speaker comparisons of comparable vowels in similar phonetic contexts. Formant frequencies of eight different Dutch-English vowel pairs that appear in interlingual homophones produced by five advanced Dutch learners of English were measured for this purpose. Statistical analyses of the acoustic data seem to point to overall distinct patterns in the positions of Dutch and English vowels, which can be related to the language-specific settings of the two languages examined. Most of all, the outcomes of the analyses seem to highlight the dynamic nature of articulation, which can explain the difficulty previous studies have encountered.


There is a substantial need for new effective therapies for patients with recurrent or refractory diffuse aggressive NHL. Efficacy and safety of sphingosomal vincristine (SV), a novel formulation of vincristine encapsulated in sphingomyelin liposomes or 'sphingosomes', were evaluated in a multinational study in aggressive NHL patients with multiple unfavorable prognostic factors. Methods: 119 pts with relapsed or refractory aggressive NHL were enrolled. SV was administered at 2 mg/m 2 without capping the dose as a 1 hr IV infusion every 2 weeks. The objective response rate (ORR) and 95% CI for the proportions and difference in proportions were calculated for the following subgroups: by age (≤ 60 vs. > 60); sensitive disease vs. resistant (refractory or relapsed within 3 months of prior treatment); IPI score 0–2 vs. 3–5; prior therapies 2 vs. >2; bone marrow involvement at baseline; and prior ABMT. Results: ORR in the entire group was 25% (7% CR/Cru and 18% PR) (ASH Abstr. 2353, 2003). Conclusion: Single-agent SV was active in heavily pretreated patients with relapsed and/or refractory NHL. A multivariate analysis showed that the two strongest predictors for response were number of prior regimens and sensitivity to the last therapy. The highest level of activity was observed in patients with sensitive disease and 2 prior regimens (ORR 64%). Response to SV in older patients was the same as in younger patients. Prior ABMT did not impact response with ORR being similar in both groups. SV was well tolerated and the safety profile was similar to standard vincristine despite a doubling of dose intensity.


As Assmann's theory proves, the Literature plays an important role for the collective memories. It changes the discourse structure of society, by means of letting marginal, repressed or forgotten voice be read, heard and then finally have the chance to be reflected. This article aims to analyze the "family trilogy" of Hurlimann, one of the most significant Swiss authors, in order to figure out the collective and literary memories associated with Jews in Switzerland and its impact on the construction of the their identity.


Bax and p53 proteins are interesting therapeutic targets, as they signal apoptosis and prevent neoplasms. In most cancers, these proteins are downregulated to support tumor survival. A C-phycpcyanin (C-PC) is a phycobiliprotein with diverse biological activities and could upregulate Bax and P53 in tumor cells. To assess the interaction between C-PC and pro-apoptotic proteins, docking is a valuable screening tool avoiding time and resources spent on in vitro experiments if this interaction does not occur in silico. Using PRISM web server (algorithm based on structural matching) the interaction of the C-PC (PDB ID: 1GH0) was verified in its complete form (Full) or just its F chain with two proapoptotic proteins (p53- PDB ID: 1C26- and Bax- PDB ID: 1F16). The C-PC does not interact with p53, only Bax in its two forms with binding energy of -1.54 (Full) and -21.97 (chain F). UCSF Chimera (program for the interactive visualization and analysis of molecular structures) revealed that the F chain was connected to Bax by two Hydrogen bonds and 180 varied connections (polar, nonpolar, favorable and unfavorable). In silico analyzes showed preferential interaction of C-PC with Bax, without any interaction with p53. The higher binding energy with the F chain in relation to the complete structure of C-PC indicates greater stability of the protein complex. The docking demonstrated the feasibility of carrying out in vitro and in vivo studies to assess the possible stimulatory role of C-PC on Bax.


Two new bothid species (Engyprosopon hensleyi and Arnoglossus sayaensis), and another (Parabothus malhensis) previously known only from a male holotype, are described from material recently collected from the western Indian Ocean (Saya de Malha Bank). Engyprosopon hensleyi differs from all known cogeners in having a more slender body, larger number of gill rakers, dark pectoral fins in males and a pair of dark spots on the caudal fin. Arnoglossus sayaensis is distinguished from other known species by a combination of meristic and morphometric characters as well as a unique caudal-fin color pattern that consists of a dark band and six dark spots. Parabothus malhensis is redescribed on the basis of female as well as male specimens. Generic placement is confirmed and sexual dimorphism (interorbital width) is noted for this species for the first time.


Packet inspection is widely employed in application-layer protocol analyzing systems to enable accurate protocol identification. Many existing systems, however, fail to meet the requirement of keeping up with wire speed in networking. There are two limitations: (1) software-based matching schemes are usually in a sequential manner which is slow and inefficient; (2) fast hardware-based matching schemes are inapplicable to network packet processing for lacking of intrinsic support for multiple flows.
 This paper proposes a novel approach for application-layer protocol identification called Co-Match, which combines software and hardware together to achieve fast and efficient signature matching for multiple flows. First, a grouping scheme is adopted to organize signatures into several matching sets. With this scheme, each packet is only matched against a subset of signatures, bringing about a remarkable improvement of matching speed in software. Second, an FPGA-based coprocessor is developed in order to support fast parallel regular expression matching for multiple flows in hardware. Moreover, a hardware-based flow-level traffic load balancer is employed to parallel multi-flow processing on multiple CPU cores. Experimental results show that our approach is efficient to handle multiple flows while system throughput can achieve the wire speed of Gigabit Ethernet links with moderate CPU usage.


A calculation of the optimal parameters of automatic control systems, which monitor the auxiliary controlled variables of the object without any constraints imposed on the relationship between the lags of the main and the auxiliary channels, is presented.


The study focuses on achieving a fast, continuous and high-resolution predicting model for temperate storm surge for Bohai Bay. Harmonic analysis was applied to provide open boundary conditions; and local deepening, water range reducing were to deal with the boundary of shallow water. The model could achieve the non-linear effect between storm surge and astronomical tide totally. Based on the upper conditions, three storm processes were simulated separately in 5min by the above-mentioned numerical model. Final results show that computed results are agreed well with observed values in three sea level and water elevation processes. We believe the model with great applicable value can accurately forecast sea levels and elevations due to storm surge in this region.


Based on the convergence theory of economic growth, this paper extends this concept to the human development index and carries out an empirical analysis of regional development in China between 1997 and 2006. Our research shows that the conditional convergence has been identified. Investment in fixed assets, government expenditure on education, health and infrastructure construction have positive effects on regional convergence of social development. Population weighted analysis of human development index provides support for weak convergence amongst provinces. Analysis of dynamics of regional distribution reveals the club convergence, which indicate two different convergence states. Central China is in the shade and lags behind, giving rise to the so-called "central downfall". To solve this problem, the "Rise of Central China" Plan is necessary to promote the connection between coastal and inland regions of China and reduce the regional development gap.


Cardiovascular disesaes are the leading cause of morbidity and mortality among diabetic patients. This study was a 12-months retrospective cross sectional audit of case folders of adult (>18 years) type 2 diabetic patients, who attended clinic at two (2) referral hospitals in North-East Nigeria, between June 2017 and May 2018. Patients' data including socio-demographic characteristics, cardiovascular risk factors, medication history and clinical characteristics were retrieved. The data were presented as proportions and percentages in tables and pie chart formats. The analysis was done using statistical package for social sciences (SPSS) version 21.0. Of the 807 case folders that were reviewed, 64.5% were female patients, with majority (61.3%) below 50 yearsof age and 90.2% were married. Over 50% had secondary/primary education and most (57.9%) were unskilled labourers. About one-third (34.6%) were engaged in moderate to regular physical activities. The prevalence of hypertension, dyslipidaemia and obesity was 84.8%, 5.1% and 47.1% respectively. More than three quarters of the patients (87%) were on multiple oralantidiabetic agents and metformin was the most prescribed medication (93.8%). The antihypertensive agents with the highest prescription rate was lisinopril (57.9%), while 50.9%, 6.5%, and 2.7% received low dose acetylsalicylic acid, lipid lowering agents and pregabalin respectively. Hypertension was the most prevalent cardiovascular risk factor in the study population, followed by overweight/obesity. The prescription rate of metformin and Lisinopril is commendable, but there is need to increase the use of statins and pregabalin in the study settings.


It is widely known in Brazil that, with the new context of the work environment, especially with the labor reforms and social security reforms in Brazil (constitutional amendment projects: PEC 6787/16 and PEC 287/16) will affect educational institutions. Besides technical skills, graduates should also have, managerial and so-called soft skills, which are characteristics usually found in successful entrepreneurs: group work, leadership, interpersonal relationships, creativity, flexibility, ethics, learning to learn, working under pressure, motivation, etc. Added to this new context, the demand for social responsibility is also a preponderant factor in the society in which we live. Therefore, a country as socially unequal as Brazil must demand from its university graduates a differentiated role, that is, a high-performance professional with an entrepreneurial or intra-entrepreneurial potential and consequently a manager of large projects that will create jobs and generate wealth for the country. Thus, we see that the entrepreneurial spirit and the ability to understand the social, political, economic, cultural environments in which the individual is inserted, present themselves as the main attributes required for a graduate in the current and future working environment. This requirement is also described in the curricular guidelines of undergraduate courses issued by the Ministry of Education's higher education department. Project Based Learning (PBL) and Entrepreneurship Education (EE) present themselves as active learning strategies for educational institutions that aim to be ahead and thus to train their student in order to face the new challenges of this new work environment. The Bota Pra Fazer UNIFEI (meaning: Make It Happen UNIFEI) program, an annual entrepreneurship competition, is an initiative of the Center of Entrepreneurship of the Federal University of Itajubá (CEUUNIFEI) with the objective of encouraging the academic community to be engaged through


The research objective is to determine the effect of service quality on the word-of-mouth of participants through the image of the institution, customer relationship management and participant satisfaction at private worker training institutions (LPKS) in Bakorwil I East Java. A total of 1,118 populations and with the Slovin formula, a total sample of 295 respondents were participants of the LPKS Hospitality and Cruise Ship training institutions in Bakorwil I East Java in 2018. Sampling used proportional random sampling. Analysis using SEM. The results showed that: 1). Service quality affects the image of the institution, CRM, and participant satisfaction. 2). The image of the institution influences the satisfaction of the trainees, and WOM. 3). CRM has no significant effect on the satisfaction of trainees, and significant on WOM trainees. 4). The satisfaction of the participants has an effect on the WOM of LPKS training participants. Given the large role of the institution's image of WOM, it is recommended that companies always maintain and enhance the image of the institution, because the image has an important role in building the impression obtained by someone about the company based on one's knowledge and experience of the company whether the company is good or not. Suggestions for other researchers should be made to increase the scope of research, taking into account broader areas, as well as grouping and segregation of respondents by district / city in East Java, so that a clearer picture of WOM participants in Private Work Training (LPKS) is obtained.


The purpose of this study was to determine the use of probiotics
Lactobacillus acidophilus and Bifidobacterium sp on feed consumption, Hen Day
Production (HDP), Feed Conversion Ratio (FCR), egg weight and analysis of
business laying hens infected with Escherichia coli. About 120 layers at 25 weeks
of age were randomized into six treatments. The treatment consisted of factors a
(infection and non-infection Escherichia coli) and factor b (basal feed, AGP and
probiotics). The results of the study gave probiotics an effect (p <0.05) on feed
consumption, HDP, FCR, egg weight and business analysis. The highest feed
consumption was found in the treatment of infectious probiotics, the highest HDP
was treated with non-infectious probiotics, the lowest FCR was non-infectious
probiotic treatment, the highest egg weight of non-infectious probiotic treatments.
Infection factors have an effect (p <0.05) on HDP, FCR, egg weight, acceptance
and profit but have no effect (p> 0.05) on feed consumption and variable costs.
There were interactions between probiotic and infection factors (p <0.05) on
HDP, FCR, egg weight, acceptance and profit but there was no interaction (p>
0.05) between probiotic and infection factors on feed consumption and variable
costs. It can be concluded that the administration of probiotics can produce good
production performance and high profits


The present study was conducted to provide some information and comparison about the effect of Mid-day Meal and enrolment in the Tribal area with respect to Urban area of Govt. Aided Primary School of West Bengal. Data was collected of 200 Teachers and 200 Parents from200 Primary School Teachers (100 Urban & 100 Tribal) and 200 Parents (100 Rural and 100 tribal) respectively in around four District of West Bengal by randomly. The results revealed that 1) Opinion of urban and tribal differ significantly with regard to Mid-day meal & enrolment in Govt. Aided Primary School 2) Urban area Teachers & Tribal area Teachers differ significantly with regard to Mid-day meal & enrolment in Govt. Aided Primary School, 3) Urban Parents & Tribal Parents differ significantly with regard to Mid-day meal & enrolment in Aided Primary School


Low order standard finite element formulations fail when subjected to bending action and when nearly or totally incompressible situations are encountered. However, due to numerical advantages, it is very desirable to have a reliable and efficient low order element, in particular for 3-D analysis. This thesis presents a new low order element which is based on a mixed interpolation of displacements (velocities), pressure and strains (velocity strains). The proposed element shows promise for general compressible and incompressible analysis of solids and fluids. We show that the element passes a numerical inf-sup test, and give results to some standard analysis problems that demonstrate the capabilities of the element. We also explore other alternatives that can be considered in the selection of the pressure as well as the strain interpolations which fail to satisfy the inf-sup condition. Thesis Supervisor: Klaus-Jiirgen Bathe Title: Professor of Mechanical Engineering


Abstract The article focuses on the non-agent construction of the ASKRIPTION of aussehen (er sieht mitgenommen aus, see basically Lasch 2016a) in the center of the considerations. On the basis of a corpuslinguistic evaluation of the KERN corpus at the DWDS it is shown that and why this construction belongs to the repertoire of linguistic patterns, which are especially established for descriptions in narrative texts.


Optical mesh network infrastructures have emerged as the technology of choice for next generation transport networks. At the same time, distributed, IP-based, control architectures have been proposed for intelligent optical networks, as a means to automate operations, enhance interoperability and facilitate the deployment of new applications. While distributed control in general enhances scalability and flexibility, it has also been observed that the requisite topology and link state information summarization may result in sub-optimal path computation, especially for shared mesh restoration paths. This paper presents a distributed control plane for optical mesh networks, focusing on the distributed path computation and provisioning mechanisms. It discusses the tradeoff between path computation efficiency for shared mesh restoration paths and the type of network link state and topology information that is disseminated via distributed routing protocols. We show that with appropriately aggregated link resource availability and sharing information the proposed distributed path computation algorithms are able to determine the shareability of restoration links with remarkable accuracy. A local channel assignment scheme, which is used in conjunction with the distributed path computation to assign shared channels when provisioning the restoration path, is also proposed. The information required to carry in the provisioning signaling messages in order to assign the shared channels at each node along the restoration path is discussed. In addition, we specify the extensions to the OSPF routing protocol that are necessary for disseminating the topology and link state information needed by the distributed path computation. We analyze the performance of path computation algorithms as well as the OSPF extensions. In particular, we study the tradeoffs of network capacity usage, computation complexity of restoration paths, control bandwidth usage for disseminating extended OSPF link state information and the amount of memory required to store the link state database.


Objective To identify mutations in the OSMR gene in a pedigree with familial primary cutaneous amyloidosis (FPCA).Methods Clinical data were collected from a pedigree with FPCA.Peripheral blood samples were obtained from the proband,his 19 relatives,and 50 unrelated healthy human controls.Genomic DNA was extracted from these blood samples,and subjected to PCR for the amplification of 18 encoding exons and their flanking sequences of the OSMR gene followed by DNA sequencing.Results A heterozygous missense mutation c.2081C > T,which leads to the substitution of proline by threonine at position 694,was detected in the OSMR gene of the proband and his affected relatives,but not in unaffected relatives or healthy controls.Conclusion The heterozygous mutation p.P694L in the OSMR gene may cause the clinical phenotype of FPCA in this family.

Key words:
Amyloidosis, familial;  Gene, OSMR;  Mutation, missense


Poisoning by antimony led to the death of a great individual in English literature. This case report gives as much of the history of the illness as can be found and tells a little about the individual.


So, you want to be a professional photographer the field and the importance of a good product your goals, aspirations and abilities - a self-analysis small business fundmentals - defining the product, developing your business plan more groundwork - your studio, pricing your product, administrative structure and computer needs developing a business identity establishing your legal business entity marketing - firing up the marketing plan and opening for business managing the cash cycle administering the business managing your time - the great juggling act don't let up on marketing! reality check - plan versus performance expense control strategies for the going concern managing growth employees your health insurance and retirement plan options tax obligations and strategies - preparing the tax returns networking - professional photographers groups and organizations the part-time photographer sample forms.


This article reports on the introduction of communications-based train control (CBTC) to two busy metro train lines in Madrid, Spain. The author explores how Metro Madrid and Bombardier completed these major resignaling projects without disrupting passenger travel. The project was completed at night, in rigid three-hour time slots, with no delays and no revenue service shutdowns. Metro Madrid installed Bombardier's Cityflo 650 moving block automatic train control (ATC) system, with driver semi-automatic train operation (STO) using radio communication between the train and wayside equipment. The conventional fixed-block interlocking remains in operation as a fall-back system. The author describes how the CBTC system works in the tunnel, how travel managers use the system for supervision and control, the working groups that were set up by Metro Madrid to plan the implementation process, the use of virtual track circuits (VTC) on one of the lines, and measures of the success of the CBTC program.


We present an exact computation of effective Hamiltonians for an elementary model obtained from the Yukawa theory by going to the limit of bare fermions being infinitely heavy and bare bosons being at rest with respect to the fermions that emit or absorb them. The coupling constant can be arbitrarily large. The Hamiltonians are computed by solving the differential equation of the renormalization group procedure for effective particles (RGPEP). Physical fermions, defined in the model as eigenstates of the effective Hamiltonians, are obtained in the form of an effective fermion dressed with a coherent state of effective bosons. The model computation illustrates the method that can be used in perturbative computations of effective Hamiltonians for realistic theories. It shows the mechanism by which the perturbative expansion and Tamm-Dancoff approximation increase in accuracy along the RGPEP evolution.


The internal stress calculation of continuous fiber reinforced composites under transverse loads is a complex problem. This paper established a stress calculation model based on "equal strain method", which greatly simplify the formula derivation. Three internal stress formulas under the transverse loads were derived based on the model. The first is the fiber stress formula, which shows that the ratio of fiber stress to load gradually decreases with increasing of fiber volume fraction. The second is the matrix stress formula, which shows the ratio of matrix stress to load gradually increases with increasing of fiber volume fraction. The third is the formula of average shear stress at the interface of fiber and matrix, which curve shows there is a maximum value of interfacial shear stress. The three formulas have important role for checking intensity.


In this paper, we discuss a control-flow transformation called loop folding, during the scheduling of register-transfer code for DSP-systems. Loop folding is functionally equivalent to data-path pipelining. An iterative loop-folding procedure, implemented in the CATHEDRAL II compiler, is presented. This technique may significantly improve the utilization of parallel hardware, available in a data path.


Abstract Introduction Dysmagnesemia has been demonstrated to be involved in the pathophysiology of kidney diseases and is common in cardiac surgical patients. It remains unknown whether changes of serum magnesium after cardiac surgery affect AKI. We aimed to investigate the association of early postoperative magnesium with cardiac surgery-associated AKI in adults. Methods We conducted a multicenter retrospective cohort study involving patients who underwent cardiac surgery in the eICU Collaborative Research Database between 2014 and 2015. AKI within 7 days after surgery was defined using both serum creatinine and urine output criteria of Kidney Disease Improving Global Outcomes definition. Postoperative AKI was analyzed using multivariable logistic regression with early postoperative serum magnesium measured within the first 24 h after surgery as a continuous variable and categorically by quartiles. Results Postoperative AKI was identified in 3498 of 6124 (57.1%) patients receiving cardiac surgery. The median (25th–75th percentiles) early postoperative serum magnesium level of the study population was 2.3 (2.0–2.7) mg/dL. Higher serum magnesium level was associated with a higher risk of developing postoperative AKI (adjusted odds ratio (OR), 1.46 per 1 mg/dL increase; 95% confidence interval (CI), 1.31–1.62; p<.001). The multivariable-adjusted ORs (95% CIs) of postoperative AKI across increasing quartiles of serum magnesium were 1.00 (referent), 1.11 (0.95–1.29), 1.30 (1.12–1.52), and 1.72 (1.47–2.02) (p for trend <.001). Conclusions These data demonstrate a significantly higher incidence of AKI in patients with higher early postoperative serum magnesium who underwent cardiac surgery.


Multiple processor systems are an integral part of today's high-performance computing environment. Such systems are often configured as a two-dimensional grid of processors called a mesh. Tasks compete for rectangular submeshes of this mesh. The choice of submesh allocation strategy can significantly affect the level of processor utilization and a task's waiting time. In addition, the execution speed of various allocation algorithms varies widely, which can further affect system performance. This paper describes and categorizes several submesh allocation strategies, including a previously unreported method that is superior to other methods in terms of execution speed. The paper includes results of simulation studies used to compare the performance characteristics of the most efficient allocation strategies in each category.


Influences of noise at contending sites on sports efficacy have always been paid close attention to.In this paper,the sources and characteristics were analyzed, and the effects of noise at competition sites on physical functions during exercise such as hearing,cardiovascular,nerve,hormone readjustment and metabolism of materials were synthetically discussed.Results showed that exposure to noise at contesting sites during exercise can speed up the occurrence of fatigue,so as to affect the sporting abilities.


I knew I was going to be stimulated by this book when I read in the preface 'In this book we try to stay with the patient'. This is not an excuse to 'bash the doctor or social worker' but a serious attempt to draw together all the threads of the various interpersonal relationships past and present which give rise first to crisis and then to care. The style of writing has some exciting aspects. First, there is a main problem running throughout, based around a young girl, Angie. Secondly, the descriptive writing with dialogue is vivid. Thirdly, the further examples for work at the end of each chapter emphasize the importance the authors place on group work. Statements are often backed by references detailed with notes. Using this structure with sensitivity but firmness we are made to look again at many assumptions and various scenarios, through different eyes. 'Knowledge of the facts shapes choice, yet it is rarely seen how selective this knowledge is.' I found myself, as a doctor, feeling sympathetic to the general practitioner in the book and then surprised by suggestions of alternative action which seemed equally obvious once stated. This felt good to me and I suspect similar reactions would arise from other professionals identifying with the various characters. As the book suggests, when we find ourselves in an unknown and potentially threatening landscape each person withdraws to familiar ground with which he can cope; for example, the doctor may reach for his prescription pad. I think the success of this book was to keep me stimulated but without too much threat. It broadened my potential response to ethical problems, and I hope some of it will remain with me in the heat and the rush of reality.


Many novel materials are under investigation for the future of superconducting radio-frequency accelerators (SRF). In particular, thin-film materials such as Nb3Sn, NbN, SIS multilayers, and also thin-film niobium on copper, may offer improvements in cost efficiency and RF performance over the standard niobium cavities. To avoid the difficulties of depositing thin films on full cavities, Cornell has developed a TE-mode sample host cavity which allows for RF measurements of large, flat samples at fields up to and over 100 mT. We present recent performance results from the cavity, reaching record high fields and quality factor using a niobium calibration plate. We also discuss plans for future collaborations.


There are many indexes to describe the whole performance of tall buildings in 'Code for seismic design of buildings' and 'Technical specification for concrete structures of tall building',for example,stiffness-weight ratio,torsional displacement ratio and period ratio,story stiffness ratio and ratio of shearing resistance capacity and so on.The applicability and limitation of these indexes are analyzed,especially to irregular tall buildings beyond the code-specification.It′s hard to calculating them correctly and the calculation results cannot guarantee the safety of high rise buildings even if they meet the demands of the code.The performance-based seismic design(PBSD) method is proposed in USA in 90′s,20th century,and it has been gradually applied in structural design of tall buildings beyond the code-specification in our country.This paper presents that how to select the performance objectives and how to carry out the performance-based seismic design according to the Code-exceeding types and degrees of high rise buildings.Applications of the PBSD method on some engineering projects,such as Changzhou Kaina Plaza,Zhejiang New World Wealth Center,Ningbo Global Shipping Plaza,and Wenzhou Lucheng Plaza,are also introduced.


We have succeeded in preparing very thin (nanometre order) alternating layers that can be called organic superlattices by using a special combination of materials, substrates and deposition conditions with good verification by various characterization techniques. Specially surface-treated single-crystal silicon substrates with hydrogen-terminated dangling bonds on the surface were used to induce van der Waals heteroepitaxial growth


Throughout the training or the entire competition competition, it provides a method for supporting the management of personal nutrition at different points. Competition it in addition to themselves information about the collected information about the person participating in Discipline, feedback based on this information provided to individuals to monitor the energy level of perspiration individuals and nutrition individual plan use this information to adjust. In one form, individual provides their information, may access the plan to nutrition customized for yourself using application web-based browser or mobile device.


The Zr3d spectrum in the XPS measurement of PZT ceramics was found to vary according to their crystalline phases. The Zr3d spectrum of the rhombohedral phase was deconvoluted to the Zr3d5/2 profile at 181.3±0.2eV (denoted as A1) and the Zr3d3/2 profile at 183.6±0.2eV (A2), corresponding to a single chemical state. In contrast, those of both the tetragonal phase and the MPB were deconvoluted to four profiles, Zr3d5/2 at 182.1±0.2eV (B1) and Zr3d3/2 at 184.5±0.2eV (B2) in addition to A1 and A2, corresponding to double chemical states. The area ratios of (B1+B2)/ (A1+A2) for the tetragonal phase and the MPB were 0.6 and 0.3, respectively. These results indicate that XPS has potential for a novel analytical application to PZT ceramics.


The aim of the article is to study the practice of regulation of migration and integration of refugees in the Eastern partnership countries of the EU to determine their positive experience and establish directions of its implementation in Ukraine. The article analyzes the approaches to the regulation of migration and integration of refugees in the countries of asylum (by the example of the policies of Armenia, Azerbaijan, Georgia, Belarus and Moldova). It is determined that the migration of refugees in these countries has a post-conflict nature, and the prerequisites for such migration are described. The experience of these countries regarding the consolidation of the rights of refugees and their status, the implementation of educational and social policies, policies in the field of accommodation and voting rights is processed. The article formulates the directions of individual policies that should be implemented in the national policy of Ukraine as one of the Eastern partnership countries, in particular, ensuring legal protection of the rights and interests of refugees, as well as political and legal guarantees of the implementation of these laws, improving the living conditions of refugees, wider access to social infrastructure, increasing employment and welfare, ensuring the availability of means of integration of migrants into the linguistic and cultural environment, obtaining education, while preserving the rights to national, ethnic and religious identification. This will strengthen the readiness of state and local government officials to work with refugees, create an appropriate information field to disseminate information about the rights of refugees, create conditions for ensuring a minimum level of well-being of refugees in the host country, and stimulate interaction between refugees and members of the host society on a conflict-free basis.


This letter presents a bifurcation analysis of the class-E inverter for switching-pattern derivations. The transition conditions of switching patterns are the same as the bifurcation condition of the border-collision bifurcation or the grazing bifurcation. Therefore, the switching-pattern distribution maps for wide parameter region can be obtained by applying the analytical algorithm of bifurcation-curve derivations.


The interferential method is presented for determining the inclination angle θ of molecules in homogeneously ordered plane-parallel liquid crystalline layers. The essence of the method is the analysis of the changes in the layer transmission caused by the change in conditions of interference. The angle θ is calculated from the exact, explicit relation where from no limitations the size of the angle results. The measuring-stand is described that enabled the method to be put into practice. The results for the PCB layer are presented by way of example.


Considering the pass-band independent of the traditional tri-band filter,a novel method is proposed,which is based on the stub loaded resonator(SLR) and defected stepped impedance resonator(DSIR).The three pass-bands are independently designed via the SLR and DSIR,the Qe of which is adjusted by the T-shaped feed line.This filter is characterized by independent pass-band design,fast design and a compact size.A tri-band filter with three pass-bands centering at 2.45/3.5/5.25 GHz is designed and fabricated.Measured results and simulation results are in good agreement.


Many parameters such as temperature,moisture,acidity,starch,reducing sugar during brewing of Dukang liquor were traced.The results indicated that changes of composition of chemicals showed regularity.Temperature increased slowly at beginning,and then maintained at high level in middle,and decreased slowly in last phase.Acidity and moisture content of grain substrate increased in fermentation.Content of starch decreased,while reducing sugar and total ester waved in fermentation.The results give some suggestions to systematical study on three-line systems "Matrix","Strains","Enzymes" in the liquor fermentation.


To provide a 1-N-phenylamino -1H- imidazole derivatives and pharmaceutical compositions containing them. The present invention The present invention also relates to a pharmaceutical composition comprising the compound. The present invention relates generally to hormone-dependent and independent of cancer, as well as to endocrine disorders. .BACKGROUND


The invention discloses a hinge type multifunctional operation machine which comprises a front frame and a back frame which are hinged. A driving front axle used for driving a front wheel is arranged on the front frame, a cab is installed on the front frame at the back of the driving front axle, a lifting door seat is installed vertically on the front frame between the driving front axle and the cab, a lifting door frame is installed on the lifting door seat in sliding mode, a speed multiplying sliding frame is installed in the lifting door frame, an accessory support is installed on the speed multiplying sliding frame, and an operation accessory is installed on the accessory support. The lifting door seat and the lifting door frame are moved to the back of the driving front axle and located between the driving front axle and the cab to enable the center of the operation machine to move backwards, and balance of the operation machine can be maintained by utilizing a slight weight box. The machine reduces vehicle body weight, reduces engine burden, can utilize a low-power engine, reduces integral machine production cost, enables energy consumption to be reduced and discharge of waste to be reduced, achieves the effects of saving energy and reducing emission and protects environment.


There are some major issues to be clarified about the quality of life in Albania. The standard of living as reflected by GDP and GDP per capita do not give the full picture of the quality of life in Albania. The indicators of standard of living given by GDP and GDP / capita do not show the real quality of life. The purpose of this research is to identify the problems about defining quality of life through accounting and to improve the reliability of parameters to be used. The methods used in the research are gathering figures, information, data, comparison of data with other countries, revealing results, giving recommendations. The main conclusion of the research is that in Albania most of the indicators of quality of life are not reliable and cannot be used to draw conclusions about the quality of life index. Citizens' level of education about the quality of life is low. Improving the quality of life is the basic and a major goal for a real guarantee on Albania's integration into regional, European and wider structures. DOI: 10.5901/mjss.2013.v4n10p312


A loss-of-thrust UAV (unmanned aerial vehicle) needs to land to a predetermined area, which not only requires a higher accuracy of landing area, but also needs to maintain a certain attitude angle. In this paper, the Schwartz inequality and state space form are used to derive the guidance law with angle constraint. The influence of heading error and angle constraint on aircraft landing area are analyzed quantitatively based on the adjoint method. The simulations show the range of the heading error and angle constraint on the condition of certain miss distance. Compared with traditional Monte-Carlo method, the method of adjoint in this paper has the advantages of small computation and simple data processing.


Traditionally,the application of aluminum alloy component in transmission trusses is mainly focused on techniques,instead of structural side,resulting in accidents or hidden troubles.In recent years,aluminum alloy structural design criterions have been established one after another both domestically and overseas.The advantages of aluminum alloy components include light weight,easy to install and transport,hard to be corroded in the air,excellent strength-to-weight ratio,and high recyclability,etc.,making it a promising candidate in transmission truss constructions.Successful practices have been shown in foreign projects.Full life cycle economy comparisons of aluminum and steel structures show that the cost of aluminum structures is about 1.2~1.5 times of that of steel structures.


Love Somehow is a thirty-minute, one-woman film in verse. It is adapted from the poem, The Same Boat, by Phil Bowen. It forms part of a project researching adapting poetry to the screen. The film explores Caitlyn's relationship with poet Dylan Thomas as she struggles with their alcoholism, lack of money and a growing family. I first directed the piece in the theatre with actress Sally George, also in the film. Griff Rhys Jones plays the voice of Dylan. The film and accompanying promo are cutting copies and will be finished by June 2016 for submission to film and poetry festivals.

Research papers about this film and the accompanying work adapting poetry to the screen have been presented at JAM conference Reading April 14th 2016, The International Screenwriters Forum, September 2015, Bath Digital Mix Conference May 2015.


BACKGROUND: Curcumin is a polyphenol used as a natural colorant or spice with pharmacological properties including analgesic, anti‐inflammatory, anticarcinogenic and antioxidant. In this work the partition of curcumin was carried out in an aqueous two‐phase system (ATPS) under different conditions. RESULTS: Liquid–liquid equilibrium data for the ATPS composed of 2‐propanol + sodium phosphate + water were determined experimentally by the turbidimetric method at temperatures T = 288.15, 293.15, 298.15 and 303.15 K and pH values 4.0 and 5.0. The phase‐forming and salting‐out capability of the mentioned salt were discussed by determination of the exclusion volume effect (EEV) and salting‐out coefficient. The partition of curcumin was carried out. In order to investigate the driving forces that govern the curcumin partition we conducted a thermodynamic study by isothermal titration calorimetry (ITC). The Gibbs free energy transfer (ΔₜᵣG), transfer enthalpy variation (ΔₜᵣH) and transfer entropy variation (TΔₜᵣS) were measured during the dye partition for the systems at 298.15 K. CONCLUSION: The increase in the pH value promoted an increase in the salting‐out effect as well as in the exclusion volume value. It was observed that the dye had a strong tendency to transfer to the alcohol‐rich top phase, showing Kₚ high values (13.725–112.764). Thermodynamic analysis indicated that curcumin partition in the ATPS at 298.15 K was entropically driven to the top phase. The high values of theoretical recovery, selectivity and partition coefficient obtained in this study show that the investigated systems may be a promising alternative for curcumin pre‐concentration and purification. © 2019 Society of Chemical Industry


Precise geoid heights are not as important for understanding Earth's gravity field, but they are important to geodesy itself, since the vertical datum is defined as geoid in a cm-level accuracy. Several high-degree geopotential models have been derived lately by using satellite tracking data such as those from Gravity Recovery and Climate Experiment (GRACE) and Gravity Field and Steady-State Ocean Circulation Explorer (GOCE), satellite altimeter data, and terrestrial and airborne gravity data. The Korean national geoid (KNGeoid) models of the National Geographic Information Institute (NGII) were developed using the latest global geopotential models (GGMs), which are combinations of gravity data from satellites and land gravity data. In this study, geoid heights calculated from the latest high-degree GGMs were used to evaluate the accuracy of the three GGMs (European Improved Gravity model of Earth by New techniques (EIGEN)-6C4, Earth Gravitational Model 2008 (EGM2008), and GOCE-EGM2008 combined model (GECO)) by comparing them with the geoid heights derived from the Global Navigation Satellite System (GNSS)/leveling of the 1182 unified control points (UCPs) that have been installed by NGII in South Korea since 2008. In addition, the geoid heights derived from the KNGeoid models were compared with the geoid heights derived from the GNSS/leveling of the 1182 UCPs to assess the accuracy of the KNGeoid models in terms of relative geoid heights for further gravimetric geoid determination studies in South Korea. As a result, the EGM2008 model could be selected as the suitable GGM from among the three GGMs for determining a gravimetric geoid model for South Korea.


A bipartite biregular (m,n;g) $(m,n;g)$ ‐graph Γ ${\rm{\Gamma }}$ is a bipartite graph of even girth g $g$ having the degree set {m,n} $\{m,n\}$ and satisfying the additional property that the vertices in the same partite set have the same degree. An (m,n;g) $(m,n;g)$ ‐bipartite biregular cage is a bipartite biregular (m,n;g) $(m,n;g)$ ‐graph of minimum order. In their 2019 paper, Filipovski, Ramos‐Rivera, and Jajcay present lower bounds on the orders of bipartite biregular (m,n;g) $(m,n;g)$ ‐graphs, and call the graphs that attain these bounds bipartite biregular Moore cages. In our paper, we improve the lower bounds obtained in the above paper. Furthermore, in parallel with the well‐known classical results relating the existence of k $k$ ‐regular Moore graphs of even girths g=6,8 $g=6,8$ , and 12 to the existence of projective planes, generalized quadrangles, and generalized hexagons, we prove that the existence of an S(2,k,v) $S(2,k,v)$ ‐Steiner system yields the existence of a bipartite biregular k,v−1k−1;6 $\left(k,\frac{v-1}{k-1};6\right)$ ‐cage, and, vice versa, the existence of a bipartite biregular (k,n;6) $(k,n;6)$ ‐cage whose order is equal to one of our lower bounds yields the existence of an S(2,k,1+n(k−1)) $S(2,k,1+n(k-1))$ ‐Steiner system. Moreover, with regard to the special case of Steiner triple systems, we completely solve the problem of determining the orders of (3,n;6) $(3,n;6)$ ‐bipartite biregular cages for all integers n≥4 $n\ge 4$ . Considering girths higher than 6, we relate the existence of generalized polygons (quadrangles, hexagons, and octagons) to the existence of (n+1,n2+1;8) $(n+1,{n}^{2}+1;8)$ ‐, (n2+1,n3+1;8) $({n}^{2}+1,{n}^{3}+1;8)$ ‐, (n,n+2;8) $(n,n+2;8)$ ‐, (n+1,n3+1;12) $(n+1,{n}^{3}+1;12)$ ‐ and (n+1,n2+1;16) $(n+1,{n}^{2}+1;16)$ ‐bipartite biregular cages, respectively. Using this connection, we also derive improved upper bounds for the orders of other classes of bipartite biregular cages of girths 8, 12, and 14.


In the wake of the financial crisis and the ensuing fiscal crisis, international organizations, as well as the EU and its Member States reacted by putting forth new tax policy regulations at the national and international level. These innovations constitute a significant change, in tax policy and for the EU fiscal regime. In this chapter, the editors give an overview of the context and process that gave rise to the boom in regulations in recent years. All chapters in the book are outlined in the context of the tax ecosystem. This setting remains as a guideline throughout the analyses of global policies in the book.


This project is aimed for thermally analyzing stress and strain on cover plate of galvanizing bath tub at Bridge & Roof co. ( I) Ltd in order to maintain 450°C in bath tub. Along with analysis part, cover plate shape was modified due to its continuous use & prevailing conditions at the workshop. The cover plate consist of insulating materials compacted to retain the heat in the bath tub. The thermal convection of air is less than thermal resistance of insulating materials used, thus heat loss is negligible. Thermal convection (air) = 0.0579 w/ (m k) Thermal Resistance (Insulator) = 7.046 w/ (m k). Thermal analysis report show, at 450°C. Deformation is effecting end portion = 2-3 mm. Stress & Strain at that portion is also low = 0.1-0.3 Mpa. Heat transfer of air is more than insulating materials. Thus, Heat transfer rate of Insulating materials being low they don't conduct heat from the bath tub to th e atmosphere. So, temperature of the bath tub is maintained. QA = 1806.25 W, Heat transfer rate of Air by convection QI = 270.43 W, Heat transfer rate of Insulation materials


I should like in these remarks to try to place the discussions of this Congress in a larger perspective and perhaps to broaden somewhat our concept of what constitutes a medical emergency, and what should be labelled as a disaster. I should also like to ask whether emergency care and disaster planning as we usually think of these activities are either affordable or useful when viewed in a global context. What are the day-to-day emergencies and major disasters of this planet, and are we addressing them properly with the emergency medical services systems as now constituted?


Velocity effects in production technology provide technological and economic advantages, but they require consideration of strain rate dependent material behaviour in numerical process modelling. This paper proposes a deep drawing process with DC06 at high strain rates of up to 100 s-1. Basis of the investigation are the results of the inverse parameter investigation at high strain rates in [1]. In addition to the velocity dependent flow curve in numerical modelling, the damage parameters are also taken into account. The drawing ratio and the punch velocity that affects the strain rate and the stress state in the deep drawing process are varied while the blank holder force is constant. Due to the high punch speed and the pronounced inhomogeneity of the strain rate over the work piece volume, the punch speed and punch force is very well suited to verify the numerical results. Additionally, the mesh dependency of the temperature evolution in the sheet metal is examined for further investigations of the adiabatic heating of the work piece during deformation in experiment and simulation. In this context, the deep drawing tools as well as the results of the numerical and experimental investigations are presented and discussed.