Progressive liver fibrosis is the primary cause of liver cirrhosis and hepatocellular carcinoma, and leads to considerable morbidity and mortality. Recent studies have demonstrated that microRNAs (miRNAs or miRs) are associated with fibrotic processes in liver disorders, although the exact role of miR-219 remains unclear and the relevant mechanisms remain to be completely understood. To the best of our knowledge, the present study was the first to demonstrate the functional implications of miR-219 expression during liver fibrosis. The present study reported that miR-219 exhibited significantly reduced expression in serum from patients and that its expression was negatively associated with clinical stage. It was also demonstrated that miR-219 attenuated angiotensin II-induced expression of pro-fibrotic markers, including α-smooth muscle actin, atlastin GTPase 1 and collagen. Additionally, a CCl4-induced mouse liver injury model was used to demonstrate that miR-219 strongly suppressed liver fibrosis in vivo. Furthermore, the present study identified tumor growth factor β receptor 2 (TGFBR2) as a direct target gene of miR-219. In conclusion, the results of the present study revealed that miR-219 may regulate pro-fibrotic markers by directly targeting the TGFBR2 gene and the miR-219/TGFBR2 signaling pathway may be a potential therapeutic target for liver fibrosis.


We studied the role played by a shift in perfusion to hypoxic lung areas after pulmonary embolism in post embolic hypoxemia. A tracheal divider was used to separate hypoxic (N2 ventilated) from oxygenated (100 per cent O2 ventilated) lung in anaesthetized dogs. Relative perfusion was assessed from total 133Xenon (133Xe) exhaled from each lung area after intravenous infusions. When one lung area was ventilated with N2 and the other with O2 at a normal PaCO2 to allow hypoxic pulmonary vasoconstriction (HPV), there was a significant (P < 0.001) shift away from the hypoxic side. Starch or blood clots were then infused to produce pulmonary emboli. Starch emboli were distributed predominantly to the oxygenated lung. After blood clot embolization in normocapnic dogs, pulmonary artery pressure increased 15 torr, perfusion to the hypoxic lung increased from 14 ± 2 to 23 ± 1 per cent, and PaO2 fell from 278 to 186 torr. When the degree of HPV was reduced in another group of dogs by hypocapnea, a similar increase in pulmonary artery pressure (14 torr) created by blood clot embolism did not shift perfusion or create hypoxemia. In all dogs the perfusion shift to hypoxic lung was sufficient to account for all the post embolic hypoxemia. In this dog model, post embolic hypoxemia is explained by preferential distribution of emboli to oxygenated lung followed by perfusion shift to hypoxic lung as the effect of HPV is overcome by pulmonary hypertension.


Videocapsule endoscopy (VCE) and double-balloon enteroscopy (DBE) are two endoscopic exams that permit the investigation of the small intestinal mucosa. There exists few studies that compare the diagnostic performance and results between these two diagnostic modalities.

 To compare the diagnostic performance between VCE and DBE.

 Retrospective study between 2016 and 2019. All patients at a tertiary care centre undergoing both VCE and DBE were recruited. Clinical and endoscopic information was compiled from patients' medical charts as well as the indications and results of the two endoscopic exams. The patients with an incomplete endoscopy report or who were unable to complete both VCE and DBE were excluded. The results of both VCE and DBE were compared using univariate analysis.

 In total, 126 patients underwent VCE. Of those patients, 15 further underwent DBE (average age: 69±17, 53% female). In total, 11 patients underwent upper DBE, 3 patients underwent lower DBE, and one patient underwent both upper and lower DBE. The indications for endoscopy were: gastrointestinal bleeding (47%), iron deficient anemia (40%), and other (13%). The VCE findings were: angiodysplasia (35%), inflammation (35%), polyp/neoplasia (20%), and other (10%). The DBE findings were: angiodysplasia (41%), normal (35%), polyp/neoplasia (12%), stenosis (6%) and other (6%). In 53% of cases there was at least one finding concordant between VCE and DBE. In only 20% of cases, DBE found a new lesion that was not seen by VCE. In comparison, 33% of DBE exams were normal despite a positive findings by VCE. The discordance between exams was possibly due to the delay between both exams (average 125 days).

 In over half of cases, there is at least one lesion consistent between both endoscopic modalities. DBE finds a new lesion that was not seen by VCE in only 20% of cases. Therefore, VCE should be the first choice in the investigation of the small intestine mucosa even though both exams seem to be complementary.

 None


Monascus strains M13(Monascus purpureus Went) was applied to make three different forms of starter cultures,inoculated to sterilized Pu-erh raw tea,the lovastatin content of fermented tea samples were determined. The results showed that the tea samples of the initial and the third turn both vaccinated with solid starter culture had the highest content of lovastatin,reached about 0.291mg/g. Sensory evaluation results showed that the tea samples had a significant characteristic of rice flavor. The tea samples applied starter cultures of Monascus strains containing lovastatin,laid the foundation for the development of lovastatin Pu erh tea.


A set of raising and lowering operators are constructed for Uq(gl(n)). Being Hermitian conjugates of one another, they are easily normalized and allow us to express arbitrary Gelfand–Tzetlin basis states as a product of lowering operators acting on the maximal weight state.


The synthesis and room temperature single-crystal X-ray structural characterization of the title compound [( PhCH =CHCH= NCHMePh )Fe(CO)2(PPh3)] are described, the first optically pure 1-azabuta-1,3-diene adduct of iron(0) to be so recorded. Crystals are orthorhombic, P212121, a 20.197(6), b 14.09(1), c 11.094(5) Ǻ, Z 4; conventional R on |F| was 0.061 for 2217 independent 'observed' (I> 3σ(I)) reflections. This compound has been employed to transfer the Fe(CO)2(PPh3) moiety to cyclic 1,3-dienes to give new complexes, including the first example of optically active dicarbonyl ( triphenyl - phosphine )(η4-1-methoxycyclohexa-1,3-diene)iron.


The idea of leisure and vacations in the Soviet Union at first glance suggests a paradox. As a system based on the labor theory of value, the USSR emphasized production as the foundation of wealth, personal worth, and the path to a society of abundance for all. Work—physical or mental—was the obligation of all citizens. But work took its toll on the human organism, and along with creating the necessary incentives and conditions for productive labor a socialist system would also include reproductive rest as an integral element of its economy. The eight-hour work day, a weekly day off from work, and an annual vacation constituted the triad of restorative and healthful rest opportunities in the emerging Soviet system of the 1920s and 1930s.


The thought of "moye as the capital of the poor" originated from Sima Qian. Developed by Ban Gu, It was enriched and advanced by Jia Sixie. At its core was the idea that the peasants should, besides their primary undertaking, furthermore pursue some commodity production. Even though they failed to pursue any commodity production, they should pay enough attention to the market in an effort to utilize it to their greatest advantage when they sell their agricultural products and byproducts on the market. Meanwhile, it can help improve their productive and living conditions. The idea itself is the product of small-scale peasant economy, combining elements of both natural and market economies, reflecting the complex and tangly relationship between the peasants and the commodity, market exchange and the traditional bazaar in feudal periods.


The Flexible Job-shop Scheduling problem(FJSP) is a generalization of the classical JSP,where operations are allowed to be processed on any among a set of available machines.According to the characteristics of the FJSP,an extended operation-based coding and its decoding mechanism of active scheduling is presented.Also,a mechanism of generating the initial solutions and two effective crossover operators and mutation operators are designed for the genetic algorithm.In order to preserve the good characteristics of the previous generation and reduce the disruptive effects of genetic operators,an improved genetic algorithm which combines elitist model and generation alteration model of genetic algorithm is proposed to solve the FJSP.The proposed algorithm is tested on a set of standard instance taken from the literature and compared with other approaches.The results have shown the effectiveness of the algorithms.


Thickness and square resistance are two significant characteristic parameters of carbon fiber materials used in gas diffusion layer(GDL).A testing rig is developed in this paper to align with the special testing requirement.When using the testing rig,it is combined with material testing system,caliper,and D.C.double bridge.By testing on different carbon fiber cloth samples,the conformity of the measuring system is verified,and the performance of the samples are compared and analyzed.The relationships among pressure,thickness,and square resistance are studied under diverse pressure condition.


Abstract A mining contractor is expected to provide equipment flexibility in spite of the fact that haulage unit production varies as mining progresses. Consequently, predicting the equipment needs well in advance is important for the mining contractor. African Mining Services (Ghana) Limited (AMS) is a mining contractor, responsible for the loading and hauling operations of Abosso Goldfields Limited (AGL) in addition to other tasks. This paper seeks to forecast the truck and shovel requirements in the Juno II Pit of AGL for the years 2001–2004. The load and haul practices of AMS have been studied using time and motion studies as well as other data collected from mine records. These data were used to construct a simulation model of the system using the SIMAN computer simulation package. This study shows that AMS will need 6, 7 and 8 Caterpillar 777D dump trucks to achieve the required production rate in December 2001, 2002 and the period 2003–2004, respectively.


The purpose of this study was to observe the types of muscle fibres and fibre size distribution of nerve to the triceps surae muscle. Ten adult human donated embalmed cadavers (five males and five females) in the Department of Anatomy, Medical University (1), Yangon, Myanmar and five human foetuses, three male foetuses and two female foetuses (crown rump lengths ranging from18 cm to 28 cm) from North Okkala General Hospital, Yangon, Myanmar, making a total of thirty lower limbson both sides were dissected. The back of thigh, back of knee region and back of leg of both sides of the lower limbs were dissected. Nerves to triceps surae of one adult specimen were post-fixed and stained neurohistologically with osmic acid to study the fibre size distribution of nerve and histochemically to demonstrate the types of muscle fibres. Altogether thirty adult human cadavers were used in this study. Histochemically, triceps surae muscle was found to be composed of white, intermediate and red type fibres with red fibres predominating. Morphometrically, nerve to medial gastrocnemius muscle in adult human cadaver contained (1605) myelinatedfibres on the right side and (1860)myelinatedfibres on the left side. Nerve to lateral gastrocnemius contained (1191) on right side and (1075) on left side. Nerve to soleus muscle contained (628) on right side and (574) on left side.Fibre sizes of these nerves ranged from less than 2.5 μ to 17.5μ. Histogram of each nerve showed unimodal distribution with a peak between (7.5μ) to (10μ).


Real-time 3D Result Visualization has become one of the elementary components of such numerical simulation codes as CFD/NHT software. It is obvious that GDI+ in C# can barely meet the need. Fortunately, there are some 3D graphics interface such as OpenGL and Direct3D, which both supply the function of API form in C. In addition, the technology of develop OpenGL in C/C ++ , VB and Fortran is already mature, while in .NET is still a challenge to programmers. The main objective of this paper is to summarize three ways of realization by C# and OpenGL, which could be taken for a general frame of numerical simulation software, taking HITurbine developed by PTT-HIT for example.


The preparation of 5α-[3β-2H]cholestan-3α-ol by isomerization of the easily accessible 5α-[3α-2H]cholestan-3β-ol was investigated. Isomerization of the mesylate in collidine–water or treatment of the 3β-ol with benzoic acid in the presence of triphenylphosphine and diethyl azodicarboxylate yielded the 3α-isomer with no loss of deuterium from C-3.


Based on multi-factor mixture experimental designs,Al_2O_3-CaO-CaF_2 system agglomerative fluxes with high toughness were investigated,and the thermal expansion coefficients of slag were determined.The complex interaction regularity among seven components in agglomerative flux on the thermal expansion coefficients of slag was studied.The relation between thermal expansion coefficients of slag and detachability was discussed and the quantatatine regression equation of thermal expansion coefficient with flux components was developed.Results showed that the addition of ZrO_2 has a significant effect on the thermal expansion coefficients of slag.When ZrO_210%,thermal expansion coefficients increase gradually with the addition of ZrO_2,but the mutual action of a small amount of ZrO_2 with MgO-CaF_2 can cause a decrease in thermal expansion coefficient.Furthermore,the ratio of MgO/CaF_2 is important to control the thermal expansion coefficients of slag,when it is close to 1,the thermal expansion coefficient decreases greatly.


Safety and protection of the environment are paramount to successful, effective operations. A prominent challenge in the offshore oil and gas industry is striking a balance between maximizing production from a field and managing risks to meet or exceed regulatory compliance and safety goals. Noble Energy currently manages integrity of its Gulf of Mexico deepwater assets through implementation of a riskbased integrity management (IM) program. The objective of this paper is to demonstrate the value of a risk-based assessment process to mitigate internal corrosion of a pipe-in-pipe (PIP) flowline by progressively advancing detailed engineering assessments from routine monitoring activities. The results improved understanding of internal corrosion degradation mechanism and allowed for an update to the IM plan for remaining service life. As part of Noble Energy's subsea IM program, annual asset risk assessments are conducted to identify, assess and control operational risks. Key performance indicators (KPIs) have been implemented to manage degradation mechanisms during design review and flag potentially unfavorable operational conditions. The exceedance of a KPI limit and the reliability of monitoring data directly affect the predictability of the associated degradation mechanisms. Elevated corrosion rates from a conservative corrosion model, combined with discrepancies in topsides corrosion coupon sampling, resulted in lower confidence for threat predictability. This prompted a more detailed assessment to confirm integrity of the flowline. The assessment included a review of design and historical monitoring data. A complete produced water analysis was executed to update the corrosion model. A flow regime analysis was conducted to assess the pipeline water-wet condition and water hold-up potential for current operational conditions. This paper presents challenges and assumptions in identifying representative load cases from a 10year operational history. The result of the assessment was the identification of areas along the flowline with medium to high water-wetting probability, and understanding of the hazards associated with internal corrosion at the identified locations. This study provided significant improvement in visibility of the internal corrosion degradation mechanism of the flowline and develop continued risk management strategy. This paper presents a holistic approach to managing internal corrosion threats for subsea flowlines. It demonstrates the value of linking data to degradation mechanisms to improve understanding of risks on


We prove that if $f:R \rightarrow S$ is a local homomorphism of noetherian local rings, and $M$ is a non-zero finitely generated or artinian $S$-module whose injective dimension over $R$ is bounded by the difference of the embedding dimensions of $R$ and $S$, then $M$ is an injective $S$-module and $f$ is an exceptional complete intersection map.


This paper analyzed representatives of the class Mammalia on the International Union for Conservation of Nature's (IUCN) Red List of threatened species and evaluated whether the Protected Areas have fulfilled their function of protecting habitats. In the literature review, Protected Areas were found to be part of programs for the protection and recovery of threatened species. However, these areas continue to be insufficient due to the increasing destruction caused by humans, mainly the degradation of habitats upon which these organisms depend. By reviewing twelve IUCN lists containing mammals (from 1964 to 2018), the number of threatened species on each list were found to be increasing, reflecting greater knowledge of mammal species. In Brazil, eight lists were reviewed. Notably, one list contained species that were not included in the subsequent list, which may imply that protections implemented for the conservation of these animals had an effect in mitigating their extinction, and the creation of Protected Areas are chief among the conservation measures that resulted in such successes.


Objective To find out the antibiotic resistance and incidence of bacterial spectrum,retrospective investigation of the respiratory secretion culture for 238 cases of patients with different conditions of refractory pneumonia was performed.Methods All the respiratory secretion samples,sputum and broncho-alveolar lavage fluid(BALF) of patients were cultured.Patients were divided into two groups according to patients' conditions,ICU group and generalward group.Results In ICU group,patients were of lower age,boys were more vulnerable,and easier to be complicated with congenital heart disease,bronchus-pulmonary hypoplasia and septicemia.The positive rate of acteria and ESBL was higher.Among those patients' sputum culture samples in ICU,the top two bacteria were Candida mycoderma(17 /109) and Klebsislla pneumoniae(15 /109).While cultured by BALF,they were Klebsislla pneumoniae(12 /109) and Escherichia coli(9 /109).Yet in general-ward,the top two bacteria were Candida mycoderma(11 /129) and Escherichiacoli(6 /129) through sputum culture.While by BALF culture,they were Klebsislla pneumoniae(12 /129) and Candida mycoderma(7 / 129).Conclusion The age of the refractory-pneumonia sufferers was lower,often complicated with some basic diseases.There were different bacteria spectra in different childrens' refractory pneumonia,therefore it is necessary to closely observe the change of bacteria during treatment and be concerned of the rational use of antibiotics.


Resonant tunneling(RT) phenomenon in double-barrier(DB) heterostructure[1,2] has a conceptual similarity to a transmission of optical waves in Fabry-Perot (FP) resonator and involves time delay. Its dynamics should be investigated since they limit the ultimate speed of RT devices. Such a study will also clarify similarities and differences between electronic and optical waves. In our previous work[3], we investigated the tunneling escape process of electrons from AlAs/GaAs/AlAs DBRT structures. The measured escape rate was well explained by the idealized theory of FP-like model, which predicts the tunneling escape time τ in DBRT structures is given by |t| 2vk/Lw, when |t|2 ≪1, where t is the transmission coefficient through the barrier, vk is the group velocity of electrons and Lw is the well width. This predicted escape time is equal to the one calculated by the sequential tunneling model, suggesting that the tunneling escape time is not strongly dependent on the coherency of electron waves. This simple relation may not hold for the tunneling process between quantum wells(QW), where resonant coupling effect plays a more sophisticated role. To clarify the resonant tunneling phenomena between QWs, we report, in this paper, our study on electron dynamics in several different double GaAs QW structures separated by thin AlAs barrier, where the coupling condition between QWs was varied by electric fields. Tunneling process was studied at ~20K by measuring time resolved photoluminescence(PL). Picosecond pulses of a mode-locked dye laser were used to generate electron hole pairs in QWs, and the subsequent PL from particular QWs was monitored by a streak camera to determine the time variation of electron density in the QWs. Note that the electrons are lost either by recombination (radiative[4] and nonradiative) and/or by tunneling process. Since the mass of heavy hole is quite heavy, hole tunneling can be neglected at least in the initial phase of tunneling.


Transl Pediatr 2021;10(4):1244-1247 | http://dx.doi.org/10.21037/tp-20-304 Leaders lead the way. They inspire and ignite in teams the desire to 'Be More and Do More'. They are recognized for the zeal they possess to have enhanced outcomes each time, every time. Ever so often, all we need is a different way to look at things. Some perspectives to consider as Radiology takes on the role of a care enabler in health care units are being discussed in this paper. These perspectives gain greater relevance in the uncertain times we currently live in. Treat them as life skills not just for leaders in positions of power and authority, but for every practitioner in the specialty.


Pollination is an often overlooked but large cost factor in crop production. In spite of the high diversity of flowers, which requires an adequate diversity of pollinators, almost all animal pollination is simplistically ascribed to the manageable but often less efficient pollinator, the European honeybee, Apis mellifera L. In the case of poor pollination by honeybees, a number of costly techniques is applied to enforce fruit set-often with poor results. Finally, growers may resort to hand pollination, which greatly raises production costs. Knowledge of the appropriate pollinator is already available in many cases, however. This is demonstrated in this paper with examples spanning the whole range of pollination syndromes. To make this knowledge accessible, an expert-based Internet-accessible database is suggested.


This paper briefly describes the structure and working principles of electrical-driven centrifugal nozzle,and testes its performance with special test-bed.The results show that rotary speed of spay dish,flow rate of nozzle and spray height have more effects on droplet size and spray width,but little on droplet distribution.Optimal spray parameters of un-manned helicopter have been obtained as 5m spray height,850mL/min flow rate,3094r/min rotary speed,296.29μm VMD,and 3.5m spray swath.


General Interest and Reviews 4487 Column Principles and Technology 4488 General Information 4488 Stationary Phases 4488 Fundamental Characterizations 4488 High-Speed Separations 4488 Comprehensive Two-Dimensional Gas Chromatography 4491 Scope 4491 Reviews 4491 Instrumentation 4491 Theory and Data Handling 4492 Applications 4493 Gas Chromatography Detectors 4494 Mass Spectrometric Detectors 4495 Spectroscopic Detectors 4495 Other Detectors 4495 Literature Cited 4496


and legal standing due to their ''foreigner'' status. Similarly, the children who were sent to their mothers' countries—Thailand and Vietnam—after their parents' split faced exclusionary treatment as ethnic minorities. Despite discrimination and daily mistreatment, their mothers or other guardians are reluctant to give up the children's Japanese or Korean citizenship—membership in countries perceived to be more advanced— hoping for a chance that the children would go back and have full access to social and economic opportunities as citizens, which seem a distant dream. Essentially, migrants' legal, social, and cultural rights become vulnerable in the territory where they are not citizens, especially for migrants with severely curtailed economic power. To maximize their chances in life, therefore, immigrants and their descendants attempt to assimilate into the mainstream society, like Eurasian Sarawakians who identify themselves as Malays. While Marriage Migration in Asia offers a variety of case studies, some analysis was uneven and limited. Acknowledging previous works' incorporation of women's agency and critical engagement with citizenship questions, Ishii states that ''these households [with marriage migrants] and their children become transgressive forces that challenge the boundaries and sovereignty of nationstates and their notions of what constitutes citizenship'' (p. 14). However, this claim of ''transgressive forces'' is only loosely sutured with the emphasis on ''multi-marginalization,'' when migrants are portrayed in less nuanced ways as hopeless victims. This could have been avoided if Marriage Migration in Asia had engaged critical theoretical and analytic discourses that have enriched the field of marriage migration studies in the last decade and more. Identity: The Necessity of a Modern Idea, by Gerald Izenberg. Philadelphia: University of Pennsylvania Press, 2016. 552 pp. $59.95 cloth. ISBN: 9780812248081.


A method of providing product purchasing information, a system and server thereof are provided to perform product sale consultation effectively using the information about products. A receiver(310) supports moving picture based bidirectional service. A receiver transmits the information about the user interest commodity information and the information about user to a return server(320). The user interest commodity information and the user information received from the receiver are transmitted from the return server to the products seller server. The products seller server confirms the user information and concerned commodity information. The products seller server provides user with the concerned commodity information.


Objective To assess the feasibility and safety of performing vaginally assisted laparoscopic hysterectomy (VALH) on enlarged uteri up to gestation size of 26 weeks. Design A prospective observational study. Setting Cairo University Hospital and author's private practice. Subjects A total of 16 women with enlarged uteri 18–26 weeks' gestation size. Intervention VALH is essentially a laparoscopic hysterectomy that is assisted at the start of the procedure by dealing with the lower pedicles and ligaments vaginally, followed by closure of the vaginal cuff before turning to laparoscopy. Main outcome measures These include uterine size and weight, surgical outcome, estimated blood loss, operative time, complications, duration of hospital stay. Results The mean weight of removed uteri was 1403 ± 582 g (range 790–2850). All procedures were successfully completed. The operating time was 133 ± 12 min (range 105–205) and was largely dependent upon the weight of the uterus. The manual morcellation of 1 kg of tissue took 55 ± 12 min. Estimated blood loss was 280 ± 10 ml (range 150–530). The duration of hospitalization was 46 ± 17 h (range 22–70). Conclusion VALH is a safe and effective technique for performing a hysterectomy in patients with large uteri up to the weight of 2850 g.


Excerpt To the editor: Despite advances in the treatment of large-cell non-Hodgkin's lymphomas (1), patients who have relapses after chemotherapy still have a poor outcome with the presently availa...


The proposal of suitable processes for glycerin removal from crude biodiesel is an important task for making the overall biodiesel production process environmentally friendly and economically viable. In this article, we propose a dry purification process for biodiesel treatment with different polymeric materials [chitosan, cellulose acetate, poly(vinyl alcohol) (PVA), and sulfonated PVA]. Except for pure PVA, all of the proposed materials were able to reduce the free glycerin content of crude biodiesel from 0.03 wt % to values lower than 0.02 wt %. When the PVA was sulfonated, the glycerin removal increased from 12 to 82% compared that of pure PVA. The glycerin content in the biodiesel sample treated with sulfonated PVA was 0.0055 wt %. Mid-IR spectrometric analysis showed that the sulfonation of PVA increased the band due to HOH stretching vibrations; this enabled greater hydrogen bonding between glycerol and the SO3 groups of the sulfonated adsorbent. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45330.


AbstractA technique was devised for promoting specific aspects of ego development in groups. In its current form, this procedure employs two visualization and art experiences and is guided by two therapeutic models, transactional analysis and existential therapy. Loevinger's conception of ego development provides a larger framework in which to place the experiences and their accompanying models and offers a hierarchy of treatment goals. Details of the procedure, along with the supporting rationale—including a description of Loevinger's scheme—are presented. Examples from applications of the procedure are also discussed, and directions for further investigation are indicated.


The invention discloses a glass fiber grid reinforced type stone-plastic plate preparation method. The glass fiber grid reinforced type stone-plastic plate preparation method is suitable for preparing a high-intensity stone-plastic sheet with high inorganic material proportion. The glass fiber grid reinforced type stone-plastic plate preparation method includes that adding raw materials for producing the stone-plastic plate to the part between an upper layer of glass fiber grid cloth and a lower layer of glass fiber grid cloth in a steel shaping mould, locking the mould after charging materials, compressing the materials, heating the mould to a certain temperature, preserving the heat for a certain time, taking out the mould, adding water to cool, and opening the mould to take out a finished product. The glass fiber grid reinforced type stone-plastic plate preparation method is good for increasing the fracture resistance, tensile strength and rupture strength of the stone-plastic plate and good for preparing the thin high-intensity stone-plastic material with high inorganic padding proportion; the production process is easy to control, the plate intensity and plate size control are precise, and the stone-plastic plate with concave stripes and convex stripes can be prepared; the glass fiber grid reinforced type stone-plastic plate preparation method lowers the production cost, improves the art appreciation and market value of the product, increases the economical benefit of an enterprise and is easy to popularize and use.


ABSTRACT This article aims to integrate two interrelated strands in critical security studies. The first is mounting evidence for the fallacy of claims for precision and accuracy in the United States 'counterterrorism' programme, particularly as it involves expanding aerial surveillance in support of operations of extrajudicial assasination. The second line of critical analysis concerns growing investment in the further automation of these operations, more specifically in the form of the US Department of Defense Algorithmic Warfare Cross-Functional Team, or Project Maven. Building upon generative intersections of critical security studies and science and technology studies (STS), I argue that the promotion of automated data analysis under the sign of artificial intelligence can only serve to exacerbate military operations that are at once discriminatory and indiscriminate in their targeting, while remaining politically and legally unaccountable.


Angle-resolved normal-emission photoelectron spectra of Cu(110) are calculated within the frame of the three-step model of photoemission with spin-orbit interaction included. Corresponding experimental spectra for linearly polarized light ($\ensuremath{\hbar}\ensuremath{\omega}=21.22$ eV) are presented and good agreement between theory and experiment is obtained. Spin-orbit coupling is important and gives rise to a detectable relaxation of single-group dipole selection rules even for materials with low atomic number. Since measured Cu(110) photoelectron spectra depend critically on the experimental angle resolution, care must be taken to seperate properly this intrinsic relativistic effect from those extrinsic effects originating from finite instrumental resolution. All features in the experimental spectra may be interpreted by direct interband transitions.


Catch and effort data from the ICCAT database were standardised using General Linear
Models to provide indices of abundance for the 2009 Atlantic MFCL stock assessment. A
systematic approach based upon inspection of diagnostics was used. While to allow analyses to
be run prior to and efficiently at the meeting and to aid in transparency the analysis was
developed using the open source R statistical environment (cran.r-project.org) and code, data
and this manuscript are all available as part of a Google code project at
http://code.google.com/p/glmscrs/


The crease recovery forces that show in bending fabrics clepend upon the deformation recovery forces ef 'the yarns forming. fabrics and the single fibers forming yarn. Since yarns are twisted more or less, the relations between the stress and the deformation of singles yarn should be studied viscoelastically. In bending fabric$ made complicatecl!y of yarns, the study of the mutual friction forces between fibers as well as the viscoelastical study is important. The fiction forces in bending fabrics actually change along the longitudinal direction of the yarn, and the analysis in Kirchhoff'si) treatment is very complicate(! and so the friction forces are not discussed in thi$ paper,


The effects of copper along with some microalloying elements and the processing parameters are modeled with artificial neural network and adaptive neuro-fuzzy inference system. Both the tools are found to be useful for modeling the effect of copper and other alloying additions along with the processing parameters on the hardness of microalloyed DP steels. In case of the neural network, the proposed committee of models is found to be effective in handling the problem of mapping the input-output relation in these steels. The increase in the number of rules is found to improve the predictability of the neuro-fuzzy inference system. The predictions made by both the models substantiate the knowledge of physical metallurgy principles.


MAGNESIUM, because of its low density, has obvious possibilities as an aircraft structural material. The useful magnesium alloys have densities in the range 1·76 to 1·83, compared with the aluminium alloys range of about 2·5 to 2·8. The melting point of magnesium is 650 deg. C., almost identical with that of aluminium (660 deg. C.), so that generally the alloys of each of these base elements have applications in much the same temperature band.


Neuroses are psychogenic disorders that develop as a result of long-term exposure to a traumatic event with low intensity and sharpness. In these cases, there is usually talked of disagreements in the family, production, and work community, which are not even perceived by the patient as a factor of emotional trauma. The depth of mental disorders is relatively low in neuroses - there are no deep disturbances of thinking, cognition and consciousness, and a critical attitude to others and one's own state is preserved. The article looks into the neurosis and its causes and correlation with other illnesses.


Time-varying mappings are used in place of a stationary mapping to improve the performance of Euclidean-space codes on ISI channels.


Hybridization often occurs at the parapatric range interface between closely related species, but fitness outcomes vary: hybrid offspring exhibit diverse rates of viability and reproduction compared with their parental species. The mobile hybrid zone between two chickadee congeners (Poecile atricapillus × Poecile carolinensis) has been well studied behaviorally and genetically, but the viability of hybrids and the underlying mechanisms contributing to hybrid fitness have remained unclear. To better characterize the fitness costs of hybridization in this system, we analyzed 21 years of data from four sites, including more than 1,400 breeding attempts by the two species, to show that rates of hatching success changed substantially as the zone of hybridization moved across the landscape. Admixture-associated declines in hatching success correlated with reduced proportions of heterogametic (female) offspring, as predicted by Haldane's rule. Our data support an underlying mechanism implicating genetic admixture of the homogametic (male) parent as the primary determinant of offspring sex ratio, via incompatibilities on the hemizygous Z chromosome. Our long-term study is the first to directly measure changes in fitness costs as a vertebrate hybrid zone moves, and it shows that changes in these costs are a way to track the distribution of a hybrid zone across the landscape.


Based on four seasonal oceanographic survey data during 1997-2000 in the East China Sea (23o30′~33oN, 118o30′~128o00′E),ecological characteristics such as quantity, community characteristics, species composition and dominant species were approached. This paper is first part; it shows that pelagic copepods abundance occupies about 55.5% of total abundance in the East China Sea and about 64.8% diet total abundance. Abundance peak occurred in autumn. Second peak occurred in summer, and the lowest abundance appeared in spring. Its horizontal distribution was not even. Normally, its abundance in coastal water is higher than that in off sea and Taiwan Strait, high abundance region appeared in convergence region of waters. Among them, its abundance value of convergence region of coastal current water and off seawater was higher than that in other mix region. Its abundance value of copepods was about 1/3 value only compared with 20 years before in the north part of the East China Sea(29°~32°N?west of 125°E). Horizontals distribution of pelagic copepods in the East China Sea is dependent upon some dominant species such as Calanus sinicus, Euchaeta concina, Eucalanus subcrassus etc.


This paper aims to re-think the role of the word similarity task in distributional semantics research. We argue while it is a valuable tool, it should be used with care because it provides only an approximate measure of the quality of a distributional model. Word similarity evaluations assume there exists a single notion of similarity that is independent of a particular application. Further, the small size and low inter-annotator agreement of existing data sets makes it challenging to find significant differences between models.


Background: Despite the high breastfeeding initiation rate in China (> 90%), the low exclusivity rate is of concern. Some traditional behaviors, combined with increasing popularity of infant formula, may negatively affect future breastfeeding rates. As suggested by the theory of planned behavior, understanding breastfeeding beliefs of young adults may help identify and address misperceptions of future parents, supporting maintenance of the current initiation rate while increasing rates of exclusivity and duration. No research has evaluated these factors among young adults in Mainland China. Objective: The objective was to explore any relationships between breastfeeding knowledge, attitudes, previous experiences, and future intention among undergraduate students in Mainland China. Methods: This was a cross-sectional, quantitative study conducted from May to June 2012. A convenience sample of 395 students from a major public university in southwest China participated in the survey. Results: Breastfeeding knowledge was moderate (76.7% of total score), and breastfeeding was considered to be painful (34.2%), to make breasts sag (43.1%), and to restrict the freedom of mothers (52.5%). In addition, 58.2% of students reported that they would feel embarrassed if they or their partners were to breastfeed in public, and acceptability of breastfeeding in public was low (34.7%). Three-fourths of the students (75.1%) expressed future breastfeeding intent, though males were more likely to report this intention (ie, to support a partner in breastfeeding) than were females (81.3% vs 71.7%, P = .04). Conclusion: To create a more breastfeeding-friendly culture, future research is warranted to explore these negative beliefs about breastfeeding and to counter misunderstandings among future parents in Mainland China.


Abstract Objective The purpose of this case report is to provide information regarding the importance and effectiveness of monthly maintenance therapy (if required) after completing full course of 36 TMS (Transcranial magnetic stimulation) sessions. (Most patients do not require the maintenance after full course of treatment.) This is the first study to evaluate the cause of relapse of depression after TMS treatment can be due to failure to do maintenance therapy, no related studies are found in the literature. Method The participant is a 57-year-old female with chronic history of treatment resistant MDD since her teenage years. She has been treated 3 times with full course of TMS treatment in 2 years with excellent results, and she went in remission from depression after every treatment. However, due to lack of her attendance for maintenance therapy, despite suggestions by the psychiatrist, her depression relapsed each time within 2–3 months. She was unable to follow-up with maintenance therapy due to her financial situation and lack of coverage of maintenance therapy cost through insurance. Result Patient was monitored from initiation of therapy each day until end with clinical rating scale PHQ9& GAD7 for depression & anxiety (in all 3 therapies in 2 years). Marked improvement was observed in her symptoms as shown with range during 3 therapies in the chart below. During each therapy, her remission started anytime from10th-14th treatment and after completion of treatment, she was in remission, fully functional & back to normal life. Clinical rating Baseline score in 3 Outcome score in therapies (Before 3 therapies (End TMS treatment of 36 TMS) PHQ-9 Range: 18-26 Range: 5-9 GAD-7 Range: 14-21 Range: 6-7 Conclusion Regardless of the limitations of the study (such as case study on one patient), our findings highly suggest that lack of maintenance therapy when needed after completing TMS treatment with full remission may be a cause of relapse of depression in MDD patients. Following through with proper maintenance therapy will prevent relapse of MDD and may have lead to more successful outcomes in subsequent patients. Randomized clinical trial is warranted on large patient population for further evaluation.


The era of big data provides the possibility of precision medicine. The most important idea we have for cancer is to divide and treat. Theoretically, each person's cancer should be different, so it is very necessary to make personalized treatment plans for different cancer patients. Subtype analysis of cancer can be viewed as a clustering problem, while ensemble clustering techniques are widely followed for their ability to combine multiple basic clusters into potentially better and more robust clusters. However, the reliability of the present ensemble clustering methods in cancer subtype analysis still needs to be improved. Therefore, we propose a double weighted ensemble clustering method (DWEC), which first derives the similarity matrix of each base cluster based on the local weighting method, and this process can be regarded as the first weighting based on clusters. Subsequently, the objective of finding the final partitions is regarded as an optimization problem, and the similarity matrix corresponding to each base cluster is weighted twice by the block coordinate descent algorithm to solve the optimal partitions result. The best experimental results were obtained in both labeled datasets and unlabeled cancer gene datasets, validating the superiority of the method. For cancer subtype analysis, although our proposed method did not show statistically significant differences in survival distributions of several subtypes in the subtype analysis of glioblastoma multiforme. However, it performed best in the results of the temporal test for all other four cancer gene data, and therefore, we conclude that our method is more effective for cancer subtype analysis compared with other methods.


This study investigated the impact ofprincipal'sleadership style and student's academic achievement in Daura education zone Katsina State. The descriptive survey design was adopted to the study ten (10) Secondary Schoos., six hundreds and ninety two (692) teachers Secondary School teachers formed the population of the study. The sample of the study consisted of two hundred and forty eight (248) teachers. The instrument used for data collection was a four Likertscale questionnaire design by the researcher. To test the reliability of the instrument of pilot study was carried out in neighboring local government Mani using fifty (50) respondents. The data collected were analyzed using frequency count and percentage score. Based on the finding the recommendations were made, the government should organize training and workshops for principals intermittently to improve their skills and competences. -------------------------------------------------------------------------------------------------------------------------------------Date of Submission: 26-05-2020 Date of Acceptance: 13-06-2020 -------------------------------------------------------------------------------------------------------------------------------------


The overall strategic objective of ESA'S Microgravity Applications Promotion Programme is to generate a European activity using the International Space Station as a facility for industrial R & D. "Applications" of microgravity may be understood as the exploitations of the ISS for applied research and as a testbed for the development of technology and processes useful on Earth and for long-duration space flight. The objective is therefore to develop projects in order to: optimise applied ground-based physical and biological processes; generate data and materials samples relevant for industrial R & D; and investigate space-related physiological changes relevant for long-duration space flight, which may also be relevant for clinical applications on Earth. The Microgravity Applications Promotion Programme has the objective to foster and to develop a first generation of projects with involvement from industry, which should demonstrate that microgravity is indeed a useful tool for industrial R & D. These projec...


The profound changes in the domestic and international situations not only provide favorable conditions for but also pose a challenge to ideological and political education of college students. As an important link between ideological and political education and social demand,entrepreneurial education is worth trying as a new and effective approach to ideological and political education in colleges and universities in the new situation.


The thermographic behaviour of bone and soft tissue tumors (168 malignant), submitted to this examination from 1971 to 1981, has been retrospectively analyzed and statistically evaluated. In the group of malignant neoplasms, thermography reached a good sensitivity (81.5%), a little better (but not significantly) in soft tissue tumors. Mainly three pathological features have been analyzed: histological type, size and site of neoplastic masses. None of them appears to be related with the result of thermographic examination. The authors emphasize (also from a possible prognostic point of view) the peculiar behaviour of Ewing's sarcoma, whose tendency to uniform distribution through the different thermographic classes cannot be currently explained.


This paper aims to engage with and respond to recent calls in the literature for a unifying theoretical framework to understand second language teacher education (SLTE). It critically reviews the major conceptualizations of SLTE in relation to the key conceptualizations of second language (L2) teaching. The review identifies shortcomings in traditional perspectives on L2 teaching and SLTE and the need to re-conceptualize SLTE as a field. A recent re-conceptualization of SLTE is seen through the shift towards a social constructivist perspective, a redefinition of the knowledge base, research that responds to the epistemological shift, and a sociocultural perspective on SLTE. The existing literature shows that although there is now a growing body of research that looks into the various dimensions of SLTE, few studies have gained a comprehensive and systematic view of the complexities of SLTE. The paper argues that a sociocultural perspective, especially a combination of Vygotsky's genetic method and Engestrom's proposal of the third generation of activity theory, has become a powerful way of understanding L2 teacher learning, which corresponds to the need for a re-conceptualization of SLTE. This paper calls for more research using a sociocultural framework to enrich its knowledge base.


There are few countries in the world where television is thought to be fulfilling its potential for the communication of culture and the illumination of public affairs: least of all is it doing so in new and small nations. Yet there is a tendency for people In each country to think that their problems are indigenous problems, that television is much better elsewhere. In some countries it is assumed that the ills of television are the result of commercial sponsorship; in some, television's cultural problems arec said to be related to political domination; in some, blame is assigned to inadequate funds, or to inadequate talent, or to the colonisation of television by the vested interests of radio. While each of these diagnoses has some substance, there is also something generically wrong. This journal article is available at ScholarlyCommons: http://repository.upenn.edu/asc_papers/166


Wide application of transgenic technology in agriculture brings the enormous benefit to the humanity,it also brings the unpredictable gene harm to the ecology and the environment.The traditional monitoring method of collecting rice pollen needs big workload and can not obtain the actual data of rice pollen's space-time distribution which the security evaluation model needs.The paper developed a portable instrument for both not disturbing the rice pollen subsidence naturely and obtaining the rice pollen's space-time distribution automatically.The rice pollen data obtained through image recognition method,enriched the data of rice pollen disfusion model,saved the human resources,and offered the powerful help for transgenic rice security monitoring and evaluating.


ABSTRACT The G20 is in transition from a short-term crisis institution to long-term steering institution, adopting a new 'G20 + established international organization' governance approach. In this approach, the main role of the G20 is to set the agenda and build political consensus for global economic governance. The established international organization provides the technical support and facilitates proposal implementation, while the precondition for the G20 institutional transition is that the emerging economies need to participate on an equal footing with the advanced economies. The case of global tax governance is among the few success stories of the G20's institutional transition. Within the 'G20 + OECD' governance architecture, the G20 builds the political consensus that the profits should be taxed where they are performed, while the OECD proposes the technical Base Erosion and Profit Shifting Action Plan. In this way, the G20's political leadership and the OECD's technical advantage complement each other, making a giant leap in global tax governance.


We show that rotating two-dimensional Fermi gases possess a nonrelativistic scale and conformal invariance at weak interactions, where the scale invariance of universal short-range interactions is not broken by quantum effects. We demonstrate the symmetry in the excitation spectrum of few-fermion ensembles in a harmonic trap obtained by exact diagonalization, which are constrained by the operator-state correspondence. The excitation spectrum is shown to split in a set of primary states, the energies of which correspond to scaling dimensions of conformal operators, and derived excited states that consist of breathing modes as well as two different center-of-mass excitations, which describe cyclotron and guiding-center excitations of the total particle cloud. Furthermore, the conformal symmetry is manifest in the many-body wave function, where it dictates the form of the hyperradial component, which we demonstrate using Monte Carlo sampling of few-body wave functions.


Throughout his philosophical career Dummett held firmly two theses: (i) the theory of meaning has a central position in philosophy and all other forms of philosophical inquiry rest upon semantic presuppositions, in particular semantic issues replace traditional metaphysical issues; (ii) the theory of meaning is a theory of understanding. I will defend neither of them. However, I will argue that there is an important lesson we ought to learn from a reflection on the link between linguistic competence and semantics, which I take to be part of Dummett's legacy in philosophy of language. I discuss the point in respect of Cappelen and Lepore's criticism of Incompleteness Arguments. 1 Dummett's Legacy: Semantics and Metaphysics Throughout his philosophical career Michael Dummett never gave up two theses: (i) The theory of meaning has a central and foundational place in philosophy. (ii) The theory of meaning is a theory of understanding. Thesis (i) is the climax of the linguistic turn started by Frege and adopted by logical positivists. It is the view that metaphysical issues must be resolved or dissolved by recourse to the theory of meaning. Contrary to positivists, who dismissed metaphysical issues either as nonsense or as issues concerning no matter of fact and reducible to pragmatic choices between different languages, Dummett never dismissed metaphysical issues as non substantive questions. Rather, he reinterpreted metaphysical disputes in any region of discourse as disputes concerning the truthconditions of the sentences in that area.1 Whether one is justified to be realist in See Dummett [8, p. xl]: "The whole point of my approach to these problems [the disputes concerning realism] has been to show that the theory of meaning underlies metaphysics. If I have made any worthwhile contribution to philosophy, I think it must lie in having raised this issue in these terms".


Optimal operation scheduling of energy storage systems (ESSs) has been considered as an effective way to cope with uncertainties arising in modern grid operation such as the inherent intermittency of the renewable energy sources (RESs) and load variations. This paper proposes a scheduling algorithm where ESS power inputs are optimally determined to minimize the microgrid (MG) operation cost. The proposed algorithm consists of two stages. In the first stage, hourly schedules during a day are optimized one day in advance with the objective of minimizing the operating cost. In the second stage, the optimal schedule obtained from the first stage is repeatedly updated every 5 min during the day of operation to compensate for the uncertainties in load demand and RES output power. The ESS model is developed considering operating efficiencies and then incorporated in mixed integer linear programming (MILP). Penalty functions are also considered to acquire feasible optimal solutions even under large forecasting errors in RES generation and load variation. The proposed algorithm is verified in a campus MG, implemented using ESSs and photovoltaic (PV) arrays. The field test results are obtained using open-source software and then compared with those acquired using commercial software.


Objective
To investigate the clinical effect and prognosis of sub-standard dose of donor stem cell infusion(DSI) mobilized by granulocyte colony-stimu1ating factor(G-CSF) in patients with relapsed acute leukemia (AL) after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Methods
From January 2010 to April 2017, a total of 17 patients with relapsed AL after allo-HSCT in Department of Hematology, the First Affiliated Hospital of Xi′an Jiaotong University were included in the study. They were divided into DSI combined chemotherapy group (n=7) and chemotherapy alone group (n=10) according to different treatment after relapse. The basic clinical data of patients with relapsed AL after allo-HSCT were collected by retrospective analysis. The infusion dose of DSI, treatment results, adverse reactions and survival outcomes were observed in both groups. Kaplan-Meier method was used to draw the overall survival (OS) and survival after first relapse (SAR) curves of two groups. The OS and SAR rate were compared by Log-rank test between two groups. This study protocol was approved by the ethics committee of the First Affiliated Hospital of Xi′an Jiaotong University (Approoal No. XJTU1AF2010LSL-020). Informed consents were obtained from all patients before treatment.

Results
① The median age of patients in DSI combined chemotherapy group was 28 years (11-49 years), 3 cases were positive in fusion gene, and 6 cases were achieved complete remission(CR)1 before transplantation, none of them had graft versus host disease(GVHD). The median age of patients in chemotherapy group was 22 years (15-37 years). The fusion gene was positive in 4 cases, and 2 cases had GVHD. ② In DSI combined chemotherapy group, 5 patients received single DSI treatment after conventional chemotherapy, and 2 patients received DSI treatment in every two weeks. Three patients (3 / 7) achieved CR. There were 4 patients with grade Ⅰ ~Ⅱ aGVHD of skin and liver, 3 patients with grade Ⅳ myelosuppression and pneumonia. Up to the end of follow-up, 1 patient survived and 6 died in DSI combined chemotherapy group. ③In the chemotherapy group, 3 patients (3 / 10) achieved CR after treatment. Up to the end of follow-up, 4 patients survived and 6 patients died. ④ The 1-year and 3-years OS rates of patients in DSI combined chemotherapy group were 57.1% and 19.0%, respectively, and those of patients in chemotherapy group were 66.7% and 17.8%, respectively. There were no significant differences between two groups (χ2 = 2.122, 0.136; P=0.58, 0.68). There was no significant difference in 1-year SAR rate between two groups (41.3% vs 29.8%; χ2=3.165, P=0.43).

Conclusions
The combination of G-CSF mobilized sub standard dose DSI with chemotherapy may improve the CR rate of patients with relapsed AL after allo-HSCT. Reducing dose of DSI may reduce the incidence of severe GVHD without affecting the therapeutic efficacy and graft versns leukemia(GVL) effect.

Key words:
Leukemia; Hematopoietic stem cell transplantation; Recurrence; Hematopoietic stem cell mobilization; Donor stem cell infusion


Cameroonian cancer patients more often consider spiritual explanations for the etiology of their sickness. In their opinion, it is the outcome of a witchcraft attack, and as such, they believe they should be treated by a traditional healer. The experience and expression of the theme of persecution, combined with the confrontation with death through cancer puts the patient in a situation akin to 'an ordeal'. Indeed, these patients often refer to an external authority when confronted with lethal danger as in other forms of ordalic behavior. The psychoanalytic psychotherapy of a female breast cancer patient allowed us to observe two types of socalled ordalic behavior: On the one hand the ancient perspective where the subject is passive, namely the perception of her sickness as the outcome of the transgression of the vow of chastity by her parents and the consequence of a witchcraft attack by the uncle; on the other hand, a more contemporary perspective with voluntary and repetitive confrontation with danger through astral travel. Both types of ordalic behavior permitted the resurgence and treatment of perinatal and periconceptional danger fantasies of the patient. As such, they allowed the reconstruction and restoration of bond and narcissism of the subject. It also showed that being around death in fantasy and reality, may be a mobilizer of the symbolization process.


We study the thermoelectric properties of three-dimensional topological insulators with many holes (or pores) in the bulk. We show that at high density of these holes, the thermoelectric figure of merit, ZT, can be large due to the contribution of the conducting surfaces and the suppressed phonon thermal conductivity. The maximum efficiency can be tuned by an induced gap in the surface states dispersion through tunneling or external magnetic fields. The large values of ZT, much higher than unity for reasonable parameters, make this system a strong candidate for applications in heat management of nanodevices, especially at low temperatures.


Gita Mehta's A River Sutra has been variously regarded as a philosophical treatise on the nature of love; as a description of the various sub-cultures within India, or sometimes even as mere entertainment – a light read. Few reviews or studies have ventured to examine the distinctively gendered nature of the narrative. This article attempts to uncover the subtle but persistent "sutra" that affirms the feminine principle throughout. The tales, beaded together in the frame narrative, connect rivers, serpents, the cult of the goddess, and the feminine principle in interesting and significant ways. It is noteworthy that this is accomplished despite the all-male coterie of characters who stud the frame narrative. The link between contemporary landscape, mythic patterns, and the feminine principle that is evidenced in the text, A River Sutra, brings to light its feminist context, one that has hitherto been overlooked.


According to video observations and analyses of 1984~1985 world swimming competitions in recent years,we found that to promote the efficiency we must make full use of the surroundings, improve the body postures and raise the effect of the limb movements.


Kron reduction is used to simplify the analysis of multi-machine power systems under certain steady state assumptions that underly the usage of phasors. In this paper we show how to perform Kron reduction for a class of electrical networks without steady state assumptions. The reduced models can thus be used to analyze the transient as well as the steady state behavior of these electrical networks.


It has been shown that student performance in chemistry problems decreases as the M demand of the problem increases, thus emphasizing the role of information processing in problem solving. It was hypothesized that manipulation (increase or decrease) of the M demand of a problem can affect student performance. Increasing the M demand of a problem would affect more the performance of subjects with a limited functional M capacity. The objective of this study is to investigate the effect of manipulation (increase) of the M demand of chemistry problems, having the same logical structure, on performance of students having different functional M capacity, cognitive style, and formal operational reasoning patterns. As predicted the performance of one group of students was lower after the manipulation (increase) in the M demand of the problem. This shows how even small changes in the amount of information required for processing can lead to working memory overload, as a consequence of a poor capacity for mobilization of M power.


The endocannabinoid system is extensively studied in neuroscience and clinical use of cannabinoid derivatives as substances with remarkable spasmolytic effects in multiple sclerosis and antiemetic potential in cancer therapy as well as pain-relieving properties is broadly acknowledged.
However, it becomes increasingly apparent, that in addition cannabinoids exert manifold functions in various organ systems, such as the immune system, the reproductive or cardiovascular system among others. Moreover, interactions with signaling pathways involved in programmed cell death, angiogenesis, metastasis or anti-tumor immunity make it highly suggestive that cannabinoids may have therapeutic potential in the treatment of cancer. Indeed, detailed reports have repeatedly shown anticancer efficacy in solid and hematologic tumor models, best characterized in human gliomas.
Anecdotal evidence of blast control in a young patient with acute myeloid leukemia has led us to systematically investigate the potential use of cannabinoids in the treatment of acute leukemia.
Owing to the critical cellular role of lysosomes in the myelination, mounting studies focus on the mechanisms underlying exocytosis of lysosome in nervous system has emerged. In this paper, we briefly introduce the recent advances in this respect.
These data are summarized herein in the context of key data regarding anticancer efficacy of cannabinoids.


Many bodies of serpentinite are scattered in and around Manhattan Island south of 59 Street based on a myriad of investigations over the years. A few years ago we reported on a newly discovered body near 43 Street and Sixth Avenue (Merguerian and Moss 2005) and our continued examination of borings has borne fruit in the form of three newly discovered small masses in northern Manhattan in an area formally mapped as Manhattan Schist (Figure 1). The present study is based solely on drill core and petrography as the borings were largely conducted for design purposes since to this day little or no excavation has taken place. Thus, the geological map and section provided below are interpretive owing to the lack of three-dimensional field data and the lack of oriented drill core. Yet the implications of the drill core analysis we performed are quite clear – sheared serpentinites occur here within a zone of mylonitic rocks formed at the contact of the Manhattan Schist and Walloomsac formations. In the past this ductile fault boundary has been named the St. Nicholas thrust and based on regional considerations it marks the Taconian frontal thrust in NYC (Merguerian 1994, 1996, 1998; Merguerian and Baskerville 1987). This extended abstract outlines the distinction between the various schist units, provides data on the lithologies, and concludes with some structural interpretations and tectonic implications of our findings.


Integrating wireless sensor networks (WSNs) in power substations for the future smart grid is growing in interest. Nevertheless, high voltage (HV) substations are harsh environments. In particular, impulsive noise needs to be taken into account. To tackle the constraints of these environments, we propose in this paper an efficient wideband channel coding scheme. The proposed approach consists in a robust physical layer based on the integration of several very interesting error correcting codes with Orthogonal Frequency Division Multiplexing (OFDM). Using real measurements of impulsive noise, the impact of rank metric (RC), Low Rank Parity Check codes (LRPC) and polar codes is evaluated in terms of BER and PER in a realistic multipath channel. The results show that using this coding scheme is very efficient in mitigating the bursty nature of impulsive noise while having a quite low level of complexity.


In order to test the effects of hyperbaric oxygen (HBO) and α-tocopherol on full-thickness skin grafts in rats, we performed full-thickness skin grafts bilaterally on rats. After surgery, we analyzed the tissue-concentrations of superoxide dismutase (SOD), catalase, and glutathione peroxidase(GPx)/reductase(GPr) on days 0, 2, 4, 7, 10, 14, 21 and 28. The four groups had similar patterns of change in SOD, catalase, GPx and GPr values. SOD increased initially, and was significantly increased at day 7, returning to the preoperative activity level on day 14 (control, HBO, and α-tocopherol treated alone) and 28 (HBO plus α-tocopherol). Catalase had a similar pattern of change as the SOD enzyme activity, except for the surgical control on day 2. Glutathione peroxidase/reductase activity in the four groups had a similar pattern of enzyme activity, with a significant increase from preoperative level on day 4, peaking during days 7 to 10, and returning to preoperative level on day 21(surgical control, HBO, and α-tocopherol-treated alone) and 28 (HBO plus α-tocopherol treated group). Hence, the clinical use of HBO and α-tocopherol mixture can be recommended as an adjunctive treatment fro free skin grafts in rats. But, the antioxidant used, its dose, and the timing of its administration, as well as, the exposure time and the pressure of HBO, should be the subject of further research.


It is done a review of evaluation methods of the inflammation in upper airways and bronchi used for diagnosis, therapeutic approach and prognosis of pathologies like rhinosinusitis and asthma. It is also analysed methods that supply relevant information of inflammation in COPD. The chronic inflammation of the airways is associated to respiratory distress, obstruction in basal lung function tests and to bronchial and nasal hyperreactivity. Computerized tomography informs about lumen dimensions, bronchial walls thickness and pulmonary density. These changes are associated to inflammation and to remodelling of the airways. Localized inflammation in respiratory tract can be


Background: Primary malignant tumors of the sternum are rare among bone tumors. Even with radical resection, the survival rate for sternal tumors remains low. Resection often results in significant bone defects in the chest wall, and reconstruction must provide adequate protection for pulmonary and respiratory structures. Flexible materials have historically been used for sternal reconstructions following failed sternotomies in cardiac surgery. Although these have had some success, they fail to provide adequate support for patients undergoing reconstruction secondary to tumor resection, who are otherwise healthy and active. Although rigid materials offer greater protection, they frequently cause chronic pain and respiratory complications. More recently, bone grafts have been used to reconstruct sternal defects, and the limited published reports are promising. Methods: We present the case of a patient diagnosed with an extramedullary solitary bone plasmacytoma who underwent a sternal resection and reconstruction with an autogenous bone graft taken from the iliac crest and secured in place with 5 plates (3 sternal and 2 mandibular). Results: At 9-month follow-up, bone marrow biopsy showed no evidence of multiple myeloma. X-ray, computed tomography, and Pulmonary Function Test (PFT) scans confirmed graft stability, and the patient has returned to normal activities. Conclusions: Sternal resection and reconstruction is an effective method for treating extramedullary solitary plasmacytoma when radiation is ineffective. In cases of significant segmental defects, iliac crest bone graft may be a viable option for repairing sternal defects following tumor resection.


Archaeological bones, found close to Mexico City (Tlatelcomila), with alterations due to probable thermal exposure attributed to a possible case of cannibalism, have been characterized by XRD, SAXS and SEM. It is shown how these non-destructive techniques, which are not conventionally used in archaeological research, may provide useful information. The deterioration degree of the bone structure is quantified through parameters such as gyration radius or fractal dimension. As some of the reported modifications could be attributed to diagenesis, a discussion is presented in terms of bone crystallinity and ionic exchange. Furthermore, the hydroxyapatite crystallite size increased depending on colour: this feature is not explained by diagenesis—it can only be attributed to temperature. We conclude that the samples were thermally treated. Indeed, thermal treatment alters the structure and morphology of bone at a very fine level (microscopic and nanometric), while morphology follows the structural modifications. It is determined that the studied human bones were treated at three different temperatures close to 100, 250 and 600°C. Therefore, they were either boiled (barbacoa) or grilled.


In this short note, we study the Fisher-KPP population model with a time-dependent Allee threshold. We consider the time dependence as sinusoidal functions and rational functions as they relate to varying environmental situations of the model. Employing the generalized Riccati equation mapping method, we obtain exact traveling wave solutions. Also, when the time-dependent Allee threshold decays to a constant value, we recover the traveling wave solution of the degenerate Fitzhugh-Nagumo equation from our general solution.


Measuring lexical similarity using WordNet has a long tradition. In the last decade, it has been challenged by distributional methods, and more recently by neural word embedding. In recent years, several larger lexical similarity benchmarks have been introduced, on which word embedding has achieved state-of-the-art results. The success of such methods has eclipsed the use of WordNet for predicting human judgments of lexical similarity. We propose a new set cardinality-based method for measuring lexical similarity, which exploits the WordNet graph, obtaining a word representation, which we called word2set, based on related neighboring words. We show that the features extracted from set cardinalities computed using this word representation, when fed into a support vector regression classifier trained on a dataset of common synonyms and antonyms, produce results competitive with those of word-embedding approaches. On the task of predicting the lexical sentiment polarity, our WordNet set-based representation significantly outperforms the classical measures and achieves the performance of neural embeddings. Although word embedding is still the best approach for these tasks, our method significantly reduces the gap between the results shown by knowledge-based approaches and by distributional representations, without requiring a large training corpus. It is also more effective for less-frequent words.


A relational analysis is made on the relationship between China's carbon emission and its influencing factors by using grey system theory and methods.The results show that coal consumption has the highest correlation degree with China's carbon emission among all influencing factors,followed by the consumption of oil,natural gas,hydropower and GDP,with nuclear power and population growth as the last two factors.The study also shows that reasonable selection of energy consumption structure in economic activities is one of the most important measures for realizing a win-win situation between carbon emission reduction and economic development.Meanwhile,based on the results of empirical study,some policy suggestions are made on how to realize the win-win outcome.


We investigate logarithmically enhanced electromagnetic corrections of all angular observables in inclusive B -> X_s l^+ l^-. We present analytical results, which are supplemented by a dedicated Monte Carlo study on the treatment of collinear photons in order to determine the size of the electromagnetic logarithms. We then give the Standard Model predictions of all observables, considering all available NNLO QCD, NLO QED and power corrections, and investigate their sensitivity to New Physics. Since the structure of the double differential decay rate is modified in the presence of QED corrections, we also propose new observables which vanish if only QCD corrections are taken into account. Moreover, we study the experimental sensitivity to these new observables at Belle II.


The utility model discloses a double-stage enthalpy-adding compressor and an air conditioner provided with the same. The compressor comprises an outer shell, a motor and a pump body assembly both arranged in the outer shell, wherein the pump body assembly comprises a crankshaft, a high-pressure stage air cylinder, a low-pressure stage air cylinder, an upper flange, a lower flange and a silencer; the upper flange is arranged on the high-pressure stage air cylinder and is provided with an upper flange exhaust hole communicated with the high-pressure stage air cylinder; the lower flange is arranged on the low-pressure stage air cylinder and is provided with a lower flange exhaust hole communicated with the low-pressure stage air cylinder; the silencer is arranged on the upper flange and is provided with a mounting hole; the crankshaft passes through the mounting hole; an exhaust opening communicated with the high-pressure stage air cylinder is arranged on the silencer; the ratio Alpha between the equivalent diameter D3 of the exhaust opening and the equivalent diameter D1 of the exhaust hole of the upper flange is 1-2; and the ratio Beta between the equivalent diameter D3 of the exhaust opening and the equivalent diameter D2 of the exhaust hole of the lower flange is 1-1.5. Through optimization of Alpha and Beta, the effects of reducing exhaust resistance of the compressor and reducing noises are realized.


Agarwala, A. N. Health Insurance in India. Allahabad: East End Publishers (on behalf of the Indian Research Assoc.), n.d. Pp. iv+144. Agarwala, A. N. Pessimism in Planning: Being an Essay on the Bottlenecks of an E~conomic Plan for India in Her Present Institutional Setting and World Position. Allahabad: Kitab-Mahal, n.d. Pp. 320. Agarwala, A. N. Social Insurance Planning in India. Allahabad: Dikshit Press, n.d. Pp. iV+2i8. Amonn, Alfred. Das Lohnproblem. Bern: A. Francke AG., I945. Pp. 78. Amonn, Alfred. Volkswirtschaftliche Grundbegriffe und Grundprobleme: Einfihrung in das volkswirtschaftliche Denken. Bern: A. Francke AG., 1944. Pp. 221. Bachmann, Hans. Die Konventionen von Bretton Woods: Internationaler Wahrungsfonds und Internationale Bank fur den Wiederaufbau, mit Ubersetzung der Vertragstexte. ("Schweizerischen Instituts fUr Aussenwirtschaftsund Marktforschung an der Handels-Hochschule St. Gallen," No. 5.) St. Gallen: Fehr'schen Buchhandlung, 1945. Pp. ix+ I40. Backman, Jules. Regulation of Prices in the Reconversion Period. New York: American Enterprise Assoc., Inc., 1945. Pp. 38. Bain, Joe S. The Economics of the Pacific Coast Petroleum Industry, Part II: Price Behavior and Competition. (Publications of "Bureau of Business and Economic Research, University of California.") Berkeley: University of California Press, 1945. Pp. XV+438. Bemis, George W. Intergovernmental Coordination of Public Works Programs in the Los Angeles Metropolitan Area. Los Angeles: Haynes Foundation, 1945. Pp. 24. Blakey, Roy G. and Gladys C. Sales Taxes and Other Excises. Chicago: Public Administration Service, 1945. Pp. XiV+2i6. Bloomfield, Arthur I. The British Balance-of-Payments Problem. ("Essays in International Finance," No. 6.) Princeton: Department of Economics and Social Institutions, International Finance Section, 1945. Pp. 28. Bohi, Hans. Grundsdtze und Methoden zur Ermittlung der richtigen Wdhrungsrelation zum A usland. ("Untersuchungen des Instituts fur Wirtschaftsforschung an der Eidgendssischen Technischen Hochschule," Band i.) Bern: A. Francke AG., 1944. Pp. 1*76. Bohler, Eugen. Grundlehren der Nationalikonomie: Eine Einfuhrung in die Wirtschaftsbetrachtung. Bern: A. Francke AG., I944. Pp. 240. Chang, Chi-yun. The National Resources of China. ("Economic Pamphlets," No. i.) New York: Sino-International Economic Research Center, I945. Pp. 7I. Chase, Stuart. Tomorrow's Trade: Problems of Our Foreign Commerce: Guide Lines to America's Future as Reported to the Twentieth Century Fund. New York: Twentieth Century Fund, 1945. Pp. x+ I56. Chou, Shun-hsin. The Capital Levy. New York: King's Crown Press, 1945. Pp. x+142. Cohen, B. J., and Towy-Evans, M. M. Working Conditions and Employee Services. London: Institute of Labour Management, 1945. Pp. 87. Cronin, John F. Economic Analysis and Problems. New York: American Book Co., I945. Pp. xv+623. Dorfman, Joseph. The Economic Mind in American Civilization, i6o6-I865. Vols. I, II. New York: Viking Press, Inc., 1946. Pp. I, xii+499+xxxi; II, vii+503-987+lv. Dtirr, Karl. Steuermathematik der A.-G. und GmbH.: Grundlagen der Steuerentlastung. Bern: Wirtschaft und Recht, I945. Pp. 23. Edwards, Corwin D.; Kreps, Theodore J.; Lewis, Ben W.; Machlup, Fritz; and Terrill, Robert P. A Cartel Policy for the United Nations. New York: Columbia University Press, 1945. Pp. Vi+ 124. Eisler, Gerhart; Norden, Albert; and Schreiner, Albert. The Lesson of Germany: A Guide to Her History. New York: International Publishers Co., Inc., 1945. Pp. 222. Fabricant, Solomon. Labor Savings in American Industry, i899-i939. ("Occasional Papers," No. 23.) New York: National Bureau of Economic Research, Inc., 1945. Pp. iv+52. Fisher, Allan G. B. Economic Progress and Social Security. London: Macmillan & Co., Ltd., 1945. Pp. xi+362. Fisher, Irving. ioo% Money: Designed To Keep Checking Banks ioo% Liquid; To Prevent Inflation and Deflation; Largely To Cure or Prevent Depressions; and To Wipe Out Much of the National Debt. Ad ed. New Haven: City Printing Co.,


A series of lanthanoid complexes (E)-1-ferrocenyl-2-(N-hexadecylpyridinium-4-yl)ethylene tetrakis(dibenzoylmethanato)lanthanoides(III) (La, Nd, Dy and Yb) have been newly synthesized for second-order nonlinear optical LB materials. The monolayer behaviors at the air-water interface, ultraviolet spectra and second-harmonic generation (SHG) of the films have been reported. The values of second-order molecular hyperpolarizability β of the complexes were estimated to be (1.37–1.58) × 10−28 esu.


Capsaicin extracted from natural sources (Capsicum frutescens) and standard capsaicin (Sigma Chemicals) were used in this study. On acute treatment capsaicin produced a dose‐related inflammatory response in rat paw as measured by the volume displacement method. This response was found to be synergestic when injected with carrageenan. Preliminary experiments showed that pretreatment with diphenhydramine‐HCl produced a significant inhibition of this acute capsaicin induced paw oedema, whereas indomethacin and methysergide were ineffective in blocking paw oedema. On the other hand, chronically capsaicin treated rats (for 10 days) showed a significant inhibition of paw oedema when treated with either carregeenan or a single high dose of capsaicin. Both the extracted and the standard capsaicin showed a similar type of response in all experiments.


The macrocycle 1,4,7-triazacyclononane-N-acetate (L) reacted
with FeCl
 3
·6H
 2
O in water to form the
monomeric complex [FeCl
 2
L] 1. Hydrolysis of
1 in the presence of an excess of sodium acetate and sodium
perchlorate yielded the binuclear complex
[Fe
 2
(µ-O)(µ-O
 2
CMe)L
 2
]ClO
 4

·NaClO
 4
·2H
 2
O 2.
Complexes 1 and 2 have been characterised by X-ray
crystallography. In 1 the Fe
 III
 is surrounded by a
distorted-octahedral array of one fac-co-ordinated triamine
ring, one monodentate carboxylato group and two chloride ligands.
Complex 2 consists of a
µ-oxo-µ-acetato-diiron(III) core with the distorted
octahedral co-ordination sphere about each Fe
 III
 being
completed by the ligand L. A sodium ion, with distorted
trigonal-bipyramidal stereochemistry, bridges between the co-ordinating
carboxylate oxygens of the terminal ligands. Complex 2 exhibits
spectroscopic features and magnetic properties similar to those of other
µ-oxo-diiron(III) complexes as well as metalloproteins
incorporating a µ-oxo-diiron(III) unit at their active
sites.


A tellurium precursor for GST in ALD or CVD process is provided to form thin GST film without auxiliary plasma at low deposit temperature. A method for forming germanium-antimon-tellulium film on a substrate comprises: a step of providing a tellulium precursor on a semiconductor substrate; a step of adding alcohol on the semiconductor substrate to form a tellulium layer; and a step of maintaining the deposit temperature at 80-500°C. The tellulium precursor is selected from (R1R2R3Si)2Te, (R1R23Si)TeR4 and (R1R2R3Si)TeN(R4R5).


cone granuloma (Fig. 4b). Given that the primary left breast cancer appeared as suspicious pleomorphic calcifications in the region of a silicone granuloma, a decision was made to biopsy the PET positive nodule despite the fact that no mammographic or ultrasound abnormality was detected in the right breast. The final pathology showed no evidence of carcinoma and was confirmed a foreign body giant cell reaction, compatible with a silicone granuloma.


Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. Institute of Pharmacology, University of Marburg, Germany. Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland. Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland. Department of Cell Biology, Albert Einstein College of Medicine, New York, U.S.A. Department of Otorhinolaryngology and Head & Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands. iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.


Simple Summary The ability of specific bioelectrical impedance vector analysis (BIVA) to classify subjects according to the percentage of fat mass has been recognized in different cross-sectional studies, but no longitudinal designs have yet been applied. The results of this investigations showed that specific BIVA can be used as a practical solution for assessing body composition management in former overweight/obese athletes. In particular, reductions in bioelectrical vector length adjusted according to the specific BIVA procedure were found to be associated with reductions in percentage of fat mass. Abstract Background: specific bioelectrical impedance vector analysis (BIVA) has been proposed as an alternative bioimpedance method for evaluating body composition. This investigation aimed to verify the ability of specific BIVA in identifying changes in fat mass after a 16-week lifestyle program in former athletes. Methods: The 94 participants included in the Champ4life project (clinicaltrials.gov: NCT03031951) were randomized into intervention (n = 49) and control (n = 45) groups, from which 82 athletes completed the intervention (age 43.9 ± 9.2 y; body mass index 31.1 ± 4.6 kg/m2). Fat mass was estimated by dual-energy X-ray absorptiometry. Bioelectric resistance, reactance, phase angle, and vector length were assessed by bioelectric impedance spectroscopy, and the BIVA procedure was applied. Results: A significant (p < 0.05) group x time interaction for fat mass, specific resistance, reactance, and vector length was found. Fat mass and vector length significantly (p < 0.05) decreased in the intervention group, while no change was measured in the control group. Considering the participants as a whole group, changes in vector length were associated with changes in fat mass percentage (r2 = 0.246; β = 0.33; p < 0.001) even after adjusting for age, sex, and group (R2 = 0.373; β = 0.23; p = 0.002). Conclusions: The specific BIVA approach is suitable to track fat mass changes during an intervention program aimed to reduce body fat in former athletes.


The mycangium is a microbe-storage organ present in several wood-feeding invertebrates; for example, it has been known for some time that bark and ambrosia beetles, and even leaf-roller weevils carry symbiotic fungi in special structures on their bodies (Beaver, 1989; Kobayashi et al, 2008). However, this organ has only been discovered recently in stag beetles (Tanahashi et al., 2010) and in a certain lizard beetle (Toki et al., 2012), probably because it is not an external structure. In their case, the mycangium is an ovipositorassociated organ, that is, an exoskeletal organ normally folded and hidden under the last tergal plate of the female's abdomen.


A collection of accessions of cultivated emmer wheat, Triticum dicoccum, was evaluated for economically important traits at Tel Hadya in northern Syria. Useful variation among and within accessions was detected for agronomic traits, including a high number of productive tillers and protein content. The results from the disease screening nurseries indicated that T. dicoccum offers a good source of resistance to common bunt and yellow rust. Most of the accessions tested were, however, susceptible to late frost, which occurred in the second season. In the dry areas of West Asia and North Africa (WANA) available moisture in the soil is limited, and biotic and other abiotic stresses, such as terminal heat stress, reduce the grain yield to a considerable extent. The present study indicates that T. dicoccum has a large potential for use in improvement of durum wheat for WANA, where 80 % of the world's production of this crop is grown.


The case and development of high capacity car in the former Soviet Union and Russia are described. Type Spectrum, main type car, import and export conditions are highlighted.


Abstract : Friendly fire continues to be a major source of casualties on the modern battlefield. The Vehicle Mounted Identification Friend or Foe (VMIFF) is a device designed to provide instantaneous feedback to the shooter identifying itself as friendly when interrogated by a friendly target laser designator or laser range finder. Current prototypes provide an omni-directional near infrared signature visible through night vision devices but not thermal imagers, and therefore are only effective during night operations. Thermal imagers require a 3-5 um mid-wave infrared (MWIR) signature. The integration of a MWIR signature into VMIFF will add a daytime capability. A new generation of compact MWIR sources is emerging to meet demands from a range of spectroscopy and communications applications. An evaluation was conducted on three commercially available thermal microradiators to determine suitability as MWIR signature generators for VMIFF applications. Frequency response and angular irradiance measurements were made in both the 3-5 um and 8-12 um regions using single-pixel thermal detectors and thermal imaging cameras. Based on data collected, a next-generation VMIFF design incorporating a thermal signature is proposed.


This paper gives a new class of generalized convex functions-strictly F-G generalized convex functions,and the conditions P1,P2 as well as their properties.It studies on the properties of strictly F-G generalized convex functions,gives two sufficient conditions of strictly F-G generalized convex functions,and points out that under certain conditions,F-G generalized convex functions which satisfies intermediate-point strictly F-G generalized convexity is strictly F-G generalized convex functions,and semi-strictly F-G generalized convex functions which satisfies intermediate-point strictly F-G generalized convexity is strictly F-G generalized convex functions.And the paper provides a realistic application of strictly F-G generalized convex functions in minimization problem.


The purpose of this study aimed to evaluate fatigue-related biochemical alterations, we measured various parameters just before and after a massage. 22 healthy female volunteers in their 20 to 40 years, were taken blood samples before and after 2 hours and half meridian massage. Fatigue substances and antioxidant enzyme related substances were analyzed. After the meridian massage, on the questionnaire of fatigue degree, person who answered 'a bit tired' or 'not tired', so called, less tired than normal status, is assorted to a healthy group. Person who answered more tired than normal status, is called a non-health group. After the meridian massage, healthy group, all 12showed lactic acid levels reduced. On the contrary, 8 in non- healthy group, showed increased levels. Uric acid after the meridian massage, increased 0.2% in the healthy group, 1% in the non-healthy group, respectively. The level of SOD after the meridian massage was obviously 2.5 times higher induction rate than in the healthy group compared with the non-healthy group. The level of GPx before the meridian massage was significantly 21% higher than in the healthy group compared with the non- healthy group. But, after the procedure, only the non-healthy group showed 7% decreased level. Based on these results, we suggest that a fast decomposition of lactic acid, SOD with the capability of induction, a high GPx concentration is considered as an important factor on the classification as ahealthy group, in the survey of fatigue levels.


In July 1976, an industrial accident contaminated a residential area surrounding Seveso, Italy, with high levels of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD). The exposure was acute, relatively pure, and affected more than 45,000 men, women, and children. By February 1978, 193 chloracne cases, mostly children, had been identified in the exposed population. 5 Twenty years after, we conducted a case-control study on subjects diagnosed with chloracne and control subjects, who had not developed chloracne after the accident, to evaluate their TCDD plasma levels, as well as the exposure-response relationship and possible determinants of susceptibility to TCDD effects in this population.


It is presented the knowledge engineering based design process for tricone bits and the principles of intelligent design systems. Based on Teamcenter, using NX system development software, taking full advantage of the existing design standard, design data, and materials such as design experiences, design criteria, tricone bit models accumulated by industry companies, a knowledge driven intelligent design system for tricone bits has been developed. It is a way of effectively reusing industrial product development knowledge, enhancing effectiveness and quality of product design, and achieving product full life cycle management.


Objective:To investigate the protective effect of supplementing qi,nourishing yin and promoting blood flow(SQNYPBF)method on sepsis-induced acute lung injury. Methods:Fifty patients with sepsis-induced acute lung injury/acute respiratory distress syndrome(ALI/ARDS)were randomly divided into control group(26 cases,2 patients lost to follow up)and observation group(24 cases,1 patient lost to follow up).Patients in both groups were treated according to international guidelines for sepsis,while cases in observation group were treated with SQNYPBF(They were intravenously dripped with Shenmai Injection and Sulfotanshinone Sodium Injection,once a day,for 7 successive days)in addition.On admission(D1),day 3(D3) and day 7(D7),arterial blood samples were taken for blood gas analysis and the oxygenation index(OI)was calculated. The concentrations of TNF-α and IL-10 in the broncho alveolar lavage fluid(BALF)and serum were detevted by ELISA. And acute physiology and chronic health evaluation(APACHE)Ⅱscores and the ICU length of stay were assessed. Results:Compared with the baseline value at D1,OI was significantly increased and APACHEⅡ scores were decreased at D3 and D7 in both groups,and TNF-α concentrations in the BALF and serum were decreased and IL-10 concentrations in the BALF and serum were increased at D7 in both groups(P0.05). The OI was significantly higher and APACHEⅡ scores were lower at D7 than that at D3 in both groups(P0.05).Compared to D3,TNF-α concentrations in the BALF and serum were decreased and IL-10 concentrations in the BALF and serum were increased at D7(P0.05). Compared with the control group,the OI was significantly increased at D7 and APACHEII scores and TNF-αconcentrations in the BALF and serum were decreased at D7,and IL-10 concentrations in the BALF and serum were increased at D7(P0.05). The ICU length of stay in observation group was shorter than that in control group(P0.05). Conclusion:SQNYPBF can reduce the sepsis-induced acute lung injury,improve the clinical condition of patients with sepsis and shorten the ICU length of stay,and regulating the balance between proinflammatory factors and anti-inflammatory factors and inhibition of inflammatory responses may be involved in the mechanism.


According to the evaluation of national mineral resource potential work,new cognition of the environment of Ashele copper of mineralization,characteristics,causes,metallogenic regularities,ore-controlling elements bring forward,Ashele copper-zinc deposit which born in Eshele rift valley with the Early-Middle Devonian volcanic-related marine volcano-sedimentary massive sulphide deposits,strictly controled by the bimodal volcanic construction.Mafic volcanic rocks and acidic volcanic rocks in the contact interface is important geological signs to find such deposits,gravity and TEM and rock geochemical exploration is the best technology combination of methods to find such deposits.


Laboratory amenability tests were run on these samples received from Four Corners Uranium Co. The discussion includes acid and carbonate leaching, ion exchange, and settling of acid-leached pulps. (auth)


1. A method for the treatment of recurrent genital herpes in a human in need of such treatment, which consists in that said human an effective amount of 9- (4-acetoxy-3-acetoxymethylbut-1-yl) -2-aminopurine (famciclovir), or a pharmaceutically acceptable salt thereof for the treatment of a treatment regimen for one day. ! 2. The method of claim 1, wherein the one-day treatment is initiated within 48 hours after rash onset. ! 3. The method of claim 2, wherein the treatment is initiated within 6 hours after onset of the rash. ! 4. The method of claim 1, wherein famciclovir is administered at a dose of 2000 mg. ! 5. The method of claim 1, wherein famciclovir is administered at a dose of 1000 mg twice in one day. ! 6. The method of claim 1, wherein famciclovir is administered at a dose of 500 mg four times during one day. ! 7. The method of claim 1, wherein famciclovir is administered at a dose of 250 mg eight times within one day. ! 8. The method of claim 1, wherein famciclovir is administered orally. ! 9. The method of claim 1, wherein the compound is penciclovir sodium salt. ! 10. The method of claim 1, wherein the compound is administered parenterally.