Reports results of a questionnaire survey of 888 UK chief librarians, conducted as part of a British Library Research and Innovation Centre research project, to identify and analyse the personal qualities demanded by Library and Information Service (LIS) employers and those personal qualities that new graduate entrants are perceived to lack. Reviews the literature on the changing role of information professionals and the importance of personal factors in library and information recruitment and presents a comprehensive list of 50 desirable personal qualities arranged under five headings: characteristics needed for a user centred approach; characteristics needed for effective team work; thinking orientation; attitude to work; and style of working. Concludes that the ability to accept pressure, deal with a range of users and respond to change, are most essential for information work. The significant overlap between those qualities felt to be most essential and those perceived to be lacking raises the concern that qualities that are high in demand are also in short supply.


The article is devoted to considering legal and religious ideas as the important factors of English identity formation and the English crown prerogatives restriction in the XVIIth century. The author analyzes the Stewarts' image in public opinion of the epoch and known public figures' views on the royal prerogative. Special attention is paid to Puritans' views (as the representatives of one of the most impressive and influential Protestant trends) on history, law, labor and public management.


This study involves administration of the NSST and Concrete Objects Test to 30 trainable mentally retarded children. A comparison of test results indicates that the use of concrete objects to measu...


In this paper, the plane two-dimension numerical simulation is used to study the scour in a river whose bed is mostly cracked bedrock at the lower reaches of a spillway. In the case of cracked bedrock, there is short of an accurate control equation to express the condition of bed surface stability, which leads to the difficult to determine the change of scouring and silting through the routine simulation. Field and expenimental data are used to analyse and generalize the erosion-resisting capability which expresses the capacity of bed surface stability, so the plane distribution of the erosion-resisting coefficient in a river bed can be determined. The plane two-dimension hydrodynamic mathematical model and the auxliary control equation of bed surface stability are used to get the plane distribution of scour and silting when the riverbed is stable.


The swine breeding in the Minas Gerais semiarid has an initial characterization, but there are prospects for growth, however due to the high temperatures verified throughout the year, production is reduced. Therefore, the objective of this work was to evaluate the effect of the climatic environment on the physiological parameters of swine matrices before and after farrowing. The experiment was carried out in a representative swine breeding farm located in the region of the Gorutuba Project, in Nova Porteirinha city, MG. Six swine matrices housed in individual bays were used. The climatic variables, air temperature, relative air humidity, dew point temperature and black globe temperature were monitored through the use of two dataloggers. The physiological parameters evaluated were: body surface temperature, respiratory rate, heart rate and rectal temperature. The environmental and physiological variables were collected at 8am, 11am, 01pm, 03pm and 05pm. Data was submitted to analysis of variance, and when significant were submitted to the Tukey test at 5% probability for comparison between the means. With the data collected, it was observed that between 01pm and 05pm h and during the post-partum period, the animals were exposed to the thermal discomfort of the environment, being the responsible factor for the alteration in the respiratory rate, especially when associated with the ingestion of foods. The mean values (p<0.05) of body and rectal surface temperature were higher in the postpartum period, but did not express thermal discomfort of the swine matrices. The raising of these animals in the semiarid Minas Gerais is possible; however, it is necessary to adopt measures such as the use of ventilators and the use of curtains to minimize the animal's caloric stress.


This paper describes an innovative learning activity for educating students about human-computer interaction. The goal of this learning activity is to familiarize students with the way instrumentalists on the one hand, and technological determinists on the other, conceive of human-technology interaction, and to assess which theory students favor. This paper describes and evaluates the efficacy of this learning activity and presents preliminary data on student responses. It also establishes a framework for understanding how students initially perceive human-technology interaction and how that understanding can be used to personalize and improve their learning. Instrumentalists believe that technology can be understood simply as a tool or neutral instrument that humans use to achieve their own ends. In contrast, technological determinists believe that technology is not fully under human control, that it has some degree of autonomy, and that it has its own ends. Exposing students to these two theories of human-technological interaction provides five benefits: First, the competing theories deepen students' ability to describe how technology and humans interact. Second, they provide an ethical framework that students can use to describe how technology and humans should interact. Third, they provide students with a vocabulary that they can use to talk about human freedom and how the design of computing technology may constrain or expand that freedom. Fourth, by challenging students to articulate what theory they favor, the learning is personalized. Fifth, because the learning activity challenges students to express their personal beliefs about how humans and technology interact, the learning activity can help instructors develop a clearer understanding of those beliefs and whether they reinforce what Erin Cech has identified as a culture of depoliticization and disengagement in engineering culture.


On 30 July 1989 Chileans cast ballots in an historic but unheralded plebiscite, and approved a massive revision of the Constitution that in 1980 the Pinochet regime had crafted to institutionalise its rule. Some observers had doubted that it would be possible to change Pinochet's prized 'Constitution of Liberty', while others have since questioned the significance of the reforms that were achieved. In fact, as a result of the July referendum, 54 modifications involving 12 of the document's 14 chapters were enacted before the Constitution even went fully into effect. Moreover, since the reestablishment of democracy in Chile, the coalition government of Patricio Aylwin has won passage of still other constitutional reforms involving administrative decentralisation, and has introduced draft legislation designed to bring about changes in the judicial and electoral systems. His successor, Christian Democrat Eduardo Frei, is also committed to reform.


FIELD: mechanics. SUBSTANCE: fixture assembly with auxiliary bolt, used for the production of aircraft structure elements, is equipped with the bolt having the first end and the second end and a head that is on the first end, the first section of bolt body that mates the bolt head and has smooth side surface of first diametre performed according to the hole surfaces in the elements for elements positioning, the second bolt body section, that is located between the first section and the second end, coaxial to the first section and having the second diametre less than the first diametre, and outer thread performed at least on the specified part of the bolt body second section. Fixture assembly is also equipped with the nut that has the first and the second side. The first hole on the first nut side has diametre more than the said first diametre, in the hole there installed the first section of bolt body with the gap, and threaded hole located in the nut second side axial to the first hole as its extension where there installed the second section of the bolt body. The connection of the second section of the stem and threaded hole is performed with the possibility of fixing the elements with each other by compression between the first nut side and bolt head. The first nut hole has more depth along the axis than threaded hole. Assembly method of aircraft structure elements includes fixing of assembly elements in the position of correct element holes alignment by the said bolt, the said nut, input of the second bolt end into the aligned holes and letting the bolt through the aligned holes with close contact of the bolt body first section with hole surfaces and element positioning and nut screwing on the bolt with the gap of nut first hole of bolt body first section part, and connection of nut threaded hole with threaded part of bolt body section with elements fixing by compression from nut first side and bolt head. EFFECT: unit assembling and disassembling is made easier, hole surfaces damage is excluded. 16 cl, 3 dwg


Research into best practice in special education has concentrated on the identification and description of practice standards against which schools can evaluate their performance and thereby guide collective efforts toward program improvement. A Queensland special school wanted to update an Australian listing of basic indicators of best educational practice for students with significant disabilities (Beamish, 1992) that they has used for over a decade. This paper reports the Participatory Action Research (PAR) process undertaken by this school to develop a contemporary listing in partnership with university colleagues. Two cycles of the process took two years. In the first cycle, staff engaged in a systematic review of the original listing and then generated new teaching practices for their school. In the second cycle, staff refined the emergent listing through internal consultation. Key learnings from this PAR experience were commitment to the reciprocities of PAR process, the value of active administrative support, and the critical leadership role of teachers.


The planned date for completion of the Opcon military command transfer plan is April 2012, just two years away. At that time, the U.S.-R.O.K. Combined Forces Command, commanded by the U.S. commander in Korea, will be terminated. Two separate military commands will be created. South Korean military forces, now under the command in wartime of the U.S. commander of CFC, will then be under the wartime command of the R.O.K. military high command.


Introduction 1.1 The biopsychosocial model 1.2 The chronic pain patient 1.3 The children of chronic pain patients 1.3.1 Empirical evidence of compromised child functioning 1.4 The present dissertation 1.5 Overview of chapters Psychosocial functioning of mothers with chronic pain: a comparison to pain-free controls. 2.


Light that enters a room through the windows exist of short wavelength radiation (visible radiation) and out long wavelength radiation (thermal radiation). The visible radiation contributes to the ...


It is reduced to methane in the exhaust, as appropriate. Possible use of the fuel in the exhaust comprising a methane combustion engine 200, the combustion exhaust gas purification provided in the exhaust passage of the engine system 300 and, with respect to the intake passage, the exhaust emission control device for the exhaust of the internal combustion engine the exhaust control device 100 of the internal combustion engine in having a and capable EGR passage 400 to reflux in HPL path, adjust the exhaust gas recirculation amount of the EGR passage possible adjusting means 407 does not include the vehicle is provided with a first control means for controlling the adjusting means the first specifying means and said the specific methane concentration for specifying the methane concentration in the exhaust gas so as to if the reference value Lee Sangil, increasing the amount of exhaust gas recirculation of the HPL path.


Juvenile laws refer to all those laws which legally define juvenile crime or delinquency and its prevention,judging,dealing with and correction. Juvenile law is originated in criminal law but has its independent system. With regard to the aspects of judging units,governing object,judging procedure,and the method of dealing with,it is different from general criminal law in that it mainly targets at protection of children. There is now a great gap between juvenile legislation in China and those in other countries,and formulating a complete and systematic juvenile law is thus an important task in the process of governing by law.


(57) Abstract: X-ray inspection apparatus, X-rays source that emits X-ray beam and (1), X-ray detector for converting the optical image to detect the X-ray image and (6), X-rays detected a vessel to a video extractor which is coupled through an optical coupling device (9) and (8). The optical pickup (11) is provided for supplying the photosensor (12) a portion of the light beam on the optical coupling means (9), the photo sensor (12) adjusts the X-ray flux from the X-ray source (1) generating a control signal for. Photo sensor (6), the sequence of the sensor elements, weighting means for the signal detected by the or each pixel in each pixel, and, have a means for determining the mean value signal from the detected weighted signal and whereby the control signals obtained in order to adjust the X-ray flux emitted from the X-ray source (1) is fed back.


ABSTRACT This report deals with a time‐resolved fluorometric determination of progesterone by reversed‐phase high‐performance liquid chromatography. The method was simple to use and performed on a C18 column, with acetonitrile/water 80:20 as mobile phase (flushed at 1 mL · min−1), and a 0.03 mol · L−1 Tb(NO3)3, 0.005 mol · L−1 SDS methanolic miscellaneous solution as post‐column reagent (added at 0.8 mL · min−1). The validation of the assay was performed for a 200‐µL injection, and it showed that this method presented no interferences with estrogens, and that it was linear in the range 5 × 10−6–75 × 10−6 mol · L−1 (correlation coefficient of 0.99), repeatable (3.7% intra‐day relative standard deviation (RSD) and 5.6% inter‐day RSD, at 40 × 10−6 mol · L−1), with a detection limit at 2.5 × 10−6 mol · L−1, and a quantification limit at 5 × 10−6 mol · L−1.


As cradles for future teachers in secondary vocational schools, vocational and technological teacher's colleges regulate their targets according to the demand of the development of the secondary vocational education. The regulated objectives definitely have a higher demand on the quality of the teachers of the colleges. This paper analyzes the basic required teacher qualities and their features in an attempt to contribute ideas to the newly restored vocational and technological teacher's education in the university.


Background. Desmoplastic melanomas with and without neurotropism are thought to be more clinically aggressive than other melanomas of comparable thickness. This study evaluates the prognostic significance of desmoplasia and neurotropism in Patients with Stage I cutaneous melanoma completely excised at the initial presentation of disease and prospectively studied for a minimum of 8 years.


discover the fine thoughts that run in the minds of the subjects. Indeed, the writing of history is the product of the interpretation of the historian, which in itself is subjective. But since history is the result of the actions of individuals, the study of biographies as well as the interpretations of the historians gives us varied and alternative interpretations of the history itself. There should not be one 'official' history. Thus Women in Southeast Asian Nationalist Movements is an important addition to the study of nationalism, especially from the perspective of women participants.


This paper investigates the adaptive practical finite-time stabilization for a class of nonstrict feedback nonlinear systems. The nonlinear systems under consideration contain unknown nonlinearities and control coefficients, and unknown deadzone and saturation input nonlinearities. Without imposing any conditions on the unknown nonlinearities, neural networks are utilized as the approximators to cope with these unknown nonlinear functions. The adding a power integrator technique is employed to construct controller and adaptive laws. The stability of the corresponding closed-loop system is proved with the help of the finite-time Lyapunov theory. Finally, two simulation examples are provided to show the validity of the proposed design method.


The aim of this work is to present possibilities of the philosophy of difference as a practice of teacher training and to open gaps for an immanent curriculum, in which there can be space for experimental practices. This work seeks to present possibilities of openings of the curriculum to the experience, taking into account some philosophical concepts, mainly the philosophy of difference, to dislocate from transcendental characteristics presented in most of the curriculums which, very often reject the possibilities of creation and innovation, since they aim to produce subjectivities ideologically pre-configured in the modern project. Following authors like Deleuze and Foucault, as well as Spinoza and Nietzsche, we can understand better some terms which have been elected as fundamentals of education, such as: conscience, project, affectivity, essence, and others, and rethink them when we put our thought in becoming. So, we are going to point out a possibility in the use of the concepts of the philosophy of difference to the field of education, and also their connections with Arts and Science thoughts. The result of this work with the thought of the philosophy of difference in training courses for teachers is to lead them to think the importance of another class practice, where the teacher gives himself the chance of experimenting himself, as well as to the students he is trying to affect. With the possibility of the experimentation by the teacher we could proliferate thoughts more open to the differences, by articulating knowledges which seek variation, and not only the homogeneity of which is always the same.


The THz spectra of MgF2 and MgF2:Co crystals have been measured by Time Domain THz Spectral technology. The optical parameters of the crystals have been calculated.


Many epidemiologic studies have shown that the increase in mortality of cardiovascular and respira- tory diseases is closely associated with elevated level of ambient respirable particulate matter, however, the toxicological mechanisms of PM10 still remain unresolved. The study progress in oxidative damage and inflam- matory injury effects of PM10 on alveolar tissue were reviewed.


A method and a system for creating and operating contents by users are provided to for a user to generate and study voice study files according to language skills of the user. A method for creating and operating contents by users includes the steps of selecting a predetermined script(S310), determining a conversion format of the selected script to a voice file(S320), and carrying out the conversion as determined(S330). The script is created by the user or provided on a web page by a web server. The conversion format is set according to the level of the user, which is set by the user of automatically set by a UGC(User Generated Contents) web server.


In this paper, we investigate the constrained attitude control problem of hypersonic vehicles (HVs). An improved prescribed performance dynamic surface control method is proposed based on an adaptive scaling strategy. Because of the uncertain time-varying disturbances, the controlled state may violate the constraint in the prescribed performance control (PPC) framework. An adaptive scaling strategy is introduced in the PPC method to avoid state violation. The performance function is scaled with respect to the state adaptively. Moreover, a nonlinear disturbance observer is used to compensate the sum of external and other internal disturbances of the system. The proposed method improves the system dynamic performance while ensuring the system robustness. Furthermore, the stability of the closed-loop system is proved by Lyapunov analysis. Finally, numerical simulations are implemented to verify the effectiveness of the PPC method and superiority over other methods.


B–Y modified silicide coatings were prepared on Nb–Si based alloy by pack cementation at 1300 °C for 10 h. The effect of Y2O3 content in the pack mixtures on microstructure and oxidation resistance of the coatings was investigated. The results show that the four coatings have similar structures, which possess a (Nb,X)Si2 outer layer and a (Nb,X)5Si3 transitional layer. Y2O3 content in the pack mixtures has an obvious effect on the Si content in the coating. The mass gains of the coatings prepared with 0.5, 1, 2 and 3 wt% Y2O3 in pack mixtures are 2.33, 1.96, 2.05 and 2.86 mg/cm after oxidation at 1250 °C for 100 h, respectively. The coating prepared with 1 wt% Y2O3 exhibits the best oxidation resistance due to the formation of a dense glass-like borosilicate scale. & 2016 The Authors. Production and hosting by Elsevier B.V. on behalf of Chinese Materials Research Society. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).


Porous polyimide (PI) synthesized from 4,4′-oxydiphthalic anhydride (ODPA) and 4,4′-diaminodiphenyl ether (ODA) monomers is a promising material with an ultralow-dielectric constant. We report here a strategy toward engineering PI films of various porous textures using a small molecular phase dispersion agent, dibutyl phthalate (DBP), as porogen. In the presence of DBP, the ODPA–ODA poly(amic acid) solution, the precursor to PI, undergoes phase separation as N,N-dimethylacetamide (DMAc) solvent is slowly evaporated, forming spherical domains of DBP phase uniformly dispersed in the polyamidic acid matrix. Upon thermal imidization, a polyimide film with high porosity is attained after acetone extraction of DBP. It is demonstrated in this study that the porous texture of PI films can be readily engineered by tailoring the initial DBP content. The average pore size increases with increasing concentration of DBP, but was no larger than 6 μm. The PI film achieves a dielectric constant of 1.7 at an optimal porosity of 72%, This study examined the pore formation mechanism, the imidization chemistry, the surface morphology, the density, the thermal stability and mechanical properties of the formed porous PI films. Thermo-gravimetric analysis indicated that porous films retain the inherent exceptional thermal stability of polyimides, with thermal decomposition onset above 500 °C in nitrogen atmosphere.


At present practical project,this paper uses the application of reinforced bar concrete slope roof for testing object.The operation of ANSYS finite element software has an analysis on structure force characteristics and optimizes for structure according to the distribution optimization.It lightens the weight,saves material and simplifies construction for slope roof and at the same time it improves the structure force situations.


The recent article of Ju and Haas (1983) contains some errors in point of fact and interpretation which are rectified in the present correspondence.


The present invention is to provide a film having excellent durability which both the power generation properties and physical durability, the polymer electrolyte to the task. The present invention provides a polymer electrolyte membrane formed contains a fluorine-based polymer electrolyte composition in the pores of the microporous membrane, wherein the microporous membrane in the pore distribution, has a distribution center in the range of the pore diameter of 0.3 ㎛ ~ 5.0 ㎛, the fluorinated polymer electrolyte composition , is the ion exchange capacity of the polymer electrolyte membrane containing 0.5 to 3.0 milliequivalents / g of fluorinated polymer electrolyte (a component).


Aim at the inefficient re-design problem occurred in the design process of many typical parts,such as cylindrical helical spring,the conception and the basic structure of the function driven cylindrical helical spring 3Dpart library are proposed in order to design the cylindrical helical spring automatically according to its usage requirements.Then the corresponding implementation technology,such as the definition of the function parameters,the function driven cylindrical helical spring design process,the automatic design and modeling program are researched.The methods provided in the paper bring a new way to develop the automatic design system or 3Dpart library of the mechanical and electrical products through the effective reusing of the design data and knowledge.


Pavement performance prediction is an essential component of pavement maintenance management system, which directly affects the choice of maintenance measures and funds. Firstly, this paper uses the Gray theoretical model to predict the status of certain highway pavement damaged. Secondly, the Grey theory and Markov prediction method are combined to forecast it. Finally, the comparison of the results between Grey theory and Markov prediction method analyzes the similarities and differences .The results show that Grey theoretical model is more suitable for recent forecasting, while combination method is suitable for longer-term forecasting.


Two cases of severe and recurrent epistaxis were treated by superselective intra-arterial embolization of the internal maxillary artery. Since a 5-6 Fr catheter was used for selective angiography, a 3 Fr catheter was employed for superselective angiography and embolization. Gelform powder was delivered into the distal internal maxillary artery by the 3 Fr catheter. There were no complications due to these procedures in either of the cases in this study. Epistaxis occurred after embolization in one case and bilateral facial artery ligation was performed. Therapeutic intra-arterial embolization of the internal maxillary artery is considered to be an effective therapy for severe epistaxis and facial artery ligation is useful for selected cases.


"The Concept of Opera in the Creation of Contemporary Dance", is a research to formulate
a concept of opera in the of contemporary dance creation. To answer this research problem use
the theory of opera in a journal article titled "Exits and Entrances: on Opera" by Peter Sellar, and
the method of creating art research or artistic research as conveyed in the journal entitled "On
Reflecting and Making in Artistic Research" written by Maarit Makela and friends. This research
is a practice based research using research methods based on library research as well as
experience and experimentation of the process of realizing dance works by combining musical
elements in vocal and dance movements, and forms of dance opera works that have been done by
researchers. Observations were carried out by means of participant action research, in which
there was involvement as well as conducting experiments in creating dance work in the form of
opera.
The works in the form of dance operas, are works that use the elements of aural and body
as a medium of expression in the presentation of his work. Its creation through aural processing
in producing an ability and body processing to produce motion so that it becomes a form of
dance opera. These dance operas revealed the problem of women as subalterns that affect men's
lives in the perspectives of mothers, wives, and couples.


NaBH4, CH3CO2H, Pd/C has been described as an effective reagent system to hydrogenate alkenes. Here, we show that the hydrogenation occurs chemoselectively, making it possible to hydrogenate alkenes under Pd/C catalysis with hydrogen created in situ without O- or N-debenzylation.


Molecular minimal residual disease (MRD) analysis is fast emerging as an essential clinical decision‐making tool for the treatment and follow‐up of mature B cell malignancies. Current EuroMRD consensus IGH real‐time quantitative polymerase chain reaction RQ‐PCR assays rely on flow cytometric assessment of diagnostic tumour burdens to construct 'normalized', patient‐specific, diagnostic DNA‐based MRD quantification standards. Here, we propose a new 'hybrid' assay that relies on plasmid‐based quantification of patient‐specific IGH VDJ targets by consensus IGH real time (RQ)‐PCR, combined with EuroMRD guidelines, for MRD monitoring in lymphoid malignancies. This assay was evaluated for MRD assessment in a total of 273 samples from 29 mantle cell lymphoma (MCL) patients treated within a Groupe Ouest Est d'Etude des Leucémies et Autres Maladies du Sang (GOELAMS) Phase II trial and was feasible, reliable and consistently comparable to gold‐standard MRD techniques (99% concordance across all samples including 32 samples within the quantitative range) when analysed in parallel (117 samples). Integrating clinical prognostic parameters and MRD status in peripheral blood at the post‐induction stage was predictive of progression‐free survival (P = 0·034) thus demonstrating the clinical utility of the approach. Plasmid‐based standards for the quantification of IGH VDJ targets are therefore confirmed to offer new opportunities for further standardization and clinical evaluation of MRD‐guided management of patients with mature B cell malignancies.


Introduction: Wolff's Law qualitatively describes the response of bone to loading conditions. This study examines the interaction and dependence of loading frequency on the fatigue response of bone under axial load. It has been surmised that exposure to elevated frequencies may increase bone stiffness. The resulting stiffness response of bone based on work generated under sinusoidal loading over a range of frequencies was investigated. Elucidating the response characteristics of bone will help to determine the optimal loading conditions which stimulate bone growth and may be applicable to the improvement of bone fusion regimens as well as design of bioreactor systems. Materials and Methods: A 10-mm trephine was used to extract the central core from 30 frozen thoracic (T9, T10, T11) porcine vertebral bodies (Animal Technologies Inc., Tyler, Texas). The resulting heights from each of the cylindrical specimens of cancellous bone were recorded and used to normalize the resulting deformation data under loading. Cylindrical specimens were milled to achieve parallel surfaces for loading in phosphate-buffered saline. Specimens were subjected to compressive sinusoidal fatigue loading from –2 N to –15 N for 535 cycles at randomly selected rates of 1 Hz, 2.5 Hz, 5 Hz, 7.5 Hz, and 10 Hz using a materials' testing machine with continuous load versus deformation data acquired at cycle number 10 and at subsequent 25 cycle intervals thereafter. Stiffness at recorded cycle intervals was computed from the elastic region of the load versus deformation curve. At each axial count, the stiffness of the loading phase of the cycle was computed by determining the slope of the load versus deformation curve in the elastic region. A plot of the mean stiffness versus cycle number at each loading frequency tested was subjected to a nonlinear analysis (Prism 5.0, GraphPad Inc., San Diego, California). The resulting curve parameters of rate (K), plateau, stiffness change (span), and half-time were normalized to initial stiffness (Y0) and statistically analyzed using a one-way repeated measures ANOVA test with a Tukey posthoc test. Results and Discussion: The results of compression based on applied loading frequency are provided. The resonant frequency of the spine has been cited at 5 Hz. In addition to this 5 Hz resonant frequency, harmonics at 1 Hz and 10 Hz were also found to increase cycles required to achieve stability, as demonstrated by statistically increased half-life values seen at these loading rates. Among the half-life values, no statistically signifi cant differences were found between the 1 Hz and 5 Hz, 1 Hz and 10 Hz, or 5 Hz and 10 Hz frequencies. All other comparisons were statistically signifi cant (P < 0.05). Conclusions: The mechanical response of bone is highly dependent on loading frequency. This study demonstrates that increased stiffness at elevated loading frequencies may lead to predisposition of pathological clinical conditions. Frequency of loading rate should be considered as stiffness changes display preferential values near 2.5 Hz, 5 Hz, and 10 Hz.


The authors have developed a tunable laser technology based on optical pumping of Yb and Er doped high phosphate glass (Laporta, 2001). Er doped glass is widely used for fiber amplifiers in the 1550nm wavelengths. High phosphate glass permits very high doping of Yb and Er so that small cavity length solid-state lasers can be built. Methods for tuning these lasers include rotating glass etalon and tunable Bragg fiber. We have developed a tunable laser using piezoelectric moveable mirror for mode selection and cavity tuning. The properties of these lasers are high SMSR and low RIN


The use of new markers (nuclear transcription factors) that define linearly-specific and prognostically important biological properties of the tumor cells allow a pathologist at the present stage optimizing the available immunohistochemical algorithms and perform accurate morphological diagnosis.


Introduction: Previous reports demonstrate that individual patients may have distinctive electrocardiographic patterns preceding atrial fibrillation (AF) onset. However, these observations are based on single recordings, and are thus limited by their "snapshot" derivation; it is unclear whether patterns observed on these recordings are consistent over time. We hypothesized that the use of an implantable loop recorder (ILR) would be feasible for serial, long‐term characterization of electrocardiographic events preceding AF onset.


Our research goal was – taking into account the needs mentioned above – developing a cadastral database of
green roofs, as well as the presentation of the first results. Main data used in the database: year of
construction, type of green roof (extensive, intensive), dimensions (m2), customer's name, contractor
company's name, maintenance services (presence, absence), irrigation system (presence, absence). The big
advantage of the database is that it can be expanded to meet additional demande, the downside is its
voluntary basis. Based on the results of three years of research we can say that spreading of green roofs in the
90s in Hungary was slow. Real breakthrough was observed from 2000, mainly due to large investments in the
city. Based on the analysis of the customers, it became clear that the growth was not due to a general increase
in environmental awareness of the people, but to the stricter rules for creating green spaces in the National
Requirements Regarding Town Planning and Construction (OTEK, annex No. 5.) The amount of green roofs
constructed (m2) has a hectic fluctuation in the studied period (1991-2012), which comes from the fact that
both office and residential buildings are mostly developed in a project-like way. The analysis of the database
showed that a total of 287,843 m2 green roofs were built in Hungary by 31/12/2012 – of which 64,799 m2 (22.75%) was extensive green roof, and 219,943 m2 (77.25%) was intensive green roof. We evaluated the analysis of the model with SPSS 20.0 for Windows software package, based on the research of HARNOS and LADANYI (2005).
The coefficient of determination R2= 0.996, so the model offers a good explanation for the data dispersion.
Processing the related ANOVA we obtained F = 1678.52, which is very high so we can claim that the choosen bi-logistic model fits well. Based on the t-tests related to the parameters (calculated values are: tχ1 = 16.43; tχ2 = 7.99; tm1 = 61.80, Tm2 = 58.75; Δt1 = 6.4, Δt2 = 4.34), we accept the parameter estimates as good ones. In the last two years decline in the construction industry has a significant influence on the development volume of green roofs which is mainly due to global trends.


Data glut or unprecedented science? A global hunt for marine microbial diversity turns up a vast, underexplored world of genes, proteins, and "species." (Read more.)


Abstract Extract Spinal abscess and cord compression as it occurs in lambs in New Zealand has previously been described by Downey (1957) who gave a brief review of nine cases and by Hartley and Kater (1962). The anatomical detail was, however, inadequate and the former author found that "it had not been possible to decide where the original focus of infection [was] situated". He did not give an histological description of the lesions and suggested that the condition could be in all instances a manifestation of navel infection with localization of bacteria in bone marrow or synovial membranes. With respect to the organisms isolated in his cases, this author was not convinced that they were primary pathogens although no reasons were given for not accepting them as such.


Objective Application mini titanium board regular treatment condylar process fracture, observe the clinical effect after operation. Methods Before 3 regular fractures adopt ear screen, cutting edges and 6 examples select rear jaw to take off cutting edges after, fracture broken end reset uses mini titanium board strong fix. Results All case techniques rear wound I issue heals up, X line inspection condylar process is good, without broken end shift, occlusion relation returns to normal. Conclusion Application mini titanium board regular treatment condylar process fracture, operation may reach dissect type reset, firmly position effect reliability, short period feasible make jaw function, it is the method of a kind of worth-while popularization.


Drugs form the cornerstone of treatment for a plethora of diseases, including kidney disease and its common comorbid conditions. Patients with kidney disease are routinely prescribed numerous drugs simultaneously. For instance, patients with CKD not dependent on dialysis are prescribed a mean of six


Investigations were conducted on the effect of sugar concentration, pH balance and high methoxy pectin concentration on quality characteristics of pineapple jam using standard analytical methods. Addition of 50% sugar improved the colour and texture of the jam. Non-sugar jam was too soft, and could not hold their form. The jam balanced to pH 3.2 and 3.5 with the addition of lemon juice as a source of acid was of acceptable finished pH. Jam colour was not greatly affected by the incorporation of lemon juice. Addition of pectin had no significant effect on the pH of the finished jam. Sufficient pectin levels (0.5%) however improved the texture, gel formation and enhanced spreadability of the jam. Non-pectin jam was hard, tough and stiff and this was more evident in the 100% sugar with no pectin jam formulations. At 1.0% pectin concentration, spreadability of the jam was poor and colour became redder. Sensory rating of the pineapple jam indicated that addition of sugar generally improved the taste acceptability of jam. Results show that there is a significant difference (p 0.5) in the jam formulations as a result of variations in concentrations of sugar, acid and pectin. For a good quality jam, a sugar concentration of at least 50%, with the addition of 0.5% pectin with pH between 3.2 and 3.5 would produce a jam of acceptable colour, spreadability, gel set and good taste as well.


Here we propose a penalized orthogonal-componentsregression (POCRE) for large p small n data. Orthogonal components are sequentially constructed to maximize, upon standardization, their correlation to the re- sponse residuals. A new penalization framework, implemented via empiri- cal Bayes thresholding, is presented to effectively identify sparse predictors of each component. POCRE is computationally efficient owing t its se- quential construction of leading sparse principal components. In addition, such construction offers other properties such as grouping highly correlated predictors and allowing for collinear or nearly collinear predictors. With multivariate responses, POCRE can construct common components and thus build up latent-variable models for large p small n data. AMS 2000 subject classifications: Primary 62J05; secondary 62H20,


Organized by SFI's Business Network and Education Offices in partnership with SFI External Professor Melanie Mitchell, this two-and-a-half day course is an intensive, immersive tour of the sciences of complexity, a broad set of efforts that seek to explain how large-scale complex, organized, and adaptive behavior can emerge from simple interactions among myriad individuals. The course is specifically designed for professionals. No significant math or science background is required. The course will provide an excellent opportunity to introduce new Business Network member executives to the sciences of complexity, as well as for experienced members to refresh their knowledge of the field.


Objective To analyze the surface of the surface-modified intraocular lenses (IOLs ) implanted into rabbits'eyes for 180 days. Methods The surface of the IOLs was observed with scanning electron microscope before operation and on day 180 postoperation. Results The surface morphology of the modified IOLs was unaffected by modification processes. The modified IOLs induced lower foreign-body reaction than that of unmodified IOLs. Conclusions The uveal biocompatibility of the surface-modified IOLs was improved.


The current lane change maneuver for vehicles in a platoon under the California PATH automated highway system (AHS) architecture is inefficient, because the follower has to split from the rest of the platoon before making a lane change. In this report, we propose to add a lane change within platoons maneuver that allows a follower to change lanes and be inserted into another platoon directly without splitting either platoon. This maneuver is performed by aligning and locking the longitudinal positions of the two platoons in adjacent lanes. The estimated improvement in the AHS utilization, in term of the space-time, is approximately 4342 ms. The longitudinal controller for the lane changing follower is designed and proved to maintain the string stability of the platoons. The leader law is modified for the common leader of the two locked platoons. An intra-platoon spacing adjustment procedure is also designed for the purpose of the proposed maneuver.


The development and stability of streamwise streaks are studied in an air-flow channel experiment at subcritical Reynolds numbers. The streaks were generated by continuous suction through small slots at the wall. The streak amplitude first grows algebraically, and if the amplitude exceeds a certain threshold secondary instability in the form of travelling waves is observed. These waves give rise to high urms values in the region of large spanwise mean flow gradient. Measurements with two hot-wire probes indicate that velocity fluctuations are 180° out of phase at two neighboring peaks at each side of a low velocity region and implies the existence of a sinuous type instability. Measurements were also made with controlled disturbances where earphones were used to force the secondary instability. Phase averaged data clearly show the oscillation of the low velocity region and also provides the growth rate, phase speed as well as amplitude and phase distributions of the secondary instability. Several of these...


Millimeter-wave (mmWave) radar is widely used in vehicles for applications such as adaptive cruise control and collision avoidance. In this paper, we propose an IEEE 802.11ad-based radar for long-range radar (LRR) applications at the 60 GHz unlicensed band. We exploit the preamble of a single-carrier physical layer frame, which consists of Golay complementary sequences with good correlation properties that make it suitable for radar. This system enables a joint waveform for automotive radar and a potential mmWave vehicular communication system based on the mmWave consumer wireless local area network standard, allowing hardware reuse. To formulate an integrated framework of vehicle-to-vehicle communication and LRR, we make typical assumptions for LRR applications, incorporating the full duplex radar operation. This new feature is motivated by the recent development of systems with sufficient isolation and self-interference cancellation. We develop single- and multi-frame radar receiver algorithms for target detection as well as range and velocity estimation for both single- and multi-target scenarios. Our proposed radar processing algorithms leverage channel estimation and time–frequency synchronization techniques used in a conventional IEEE 802.11ad receiver with minimal modifications. Analysis and simulations show that in a single-target scenario, a gigabits-per-second data rate is achieved simultaneously with cm-level range accuracy and cm/s-level velocity accuracy. The target vehicle is detected with a high probability (above 99.99 $\%$) at a low false alarm rate of 10 $^{-6}$ for an equivalent isotropically radiated power of 40 dBm up to a vehicle separation distance of about 200 m. The proposed IEEE 802.11ad-based radar meets the minimum accuracy/resolution requirement of range and velocity estimates for LRR applications.


The research is to support the website using two methods, PIECES and End-User Satisfaction (EUCS). The results showed that not all variables of the two methods have an influence on user satisfaction, the variable of the lowest PIECES method on user satisfaction is service variable (service), and the variable that most influences user satisfaction from the End User Computation User Satisfaction method is the timeliness variable. the results of testing and analysis of the quality of the website showed that there were satisfied and less satisfied respondents with the website. The PIECES method and the EUCS method prove that in terms of performance, control, service, accuracy, appearance, ease of use and accuracy on the website it is good enough to meet user satisfaction while in terms of information, economy, efficiency, and content produced by the average respondent still not satisfied and must be developed again.


Objectives: To deliver excellent performance when compared to existing method Mining Comprehensible Classification Rules for Time-Series (MCCR-TS) using zoo dataset collected from UCI repository comprising of more than 1000 records. Methods/Analysis: Research works on Time-series data has been evolving as a new trend in current scenarios due to the wide range of applications involved in it. One of the widely researched topics is the web usage mining and effective evaluation of time-series movements and transaction associated with them. Most of the studies conducted earlier, focused on identifying the time-series data from the entire logs. However, this type of patterns may not be accurate enough for evaluation due to differentiated behaviors of user patterns are not taken into consideration. Findings: In this paper, we examine the time series for temporal data using integrated cluster-based rule induction mining, by presenting a novel algorithm, namely, Integrated Cluster-based Rule Induction Mining for Time-Series analysis (ICRIM-TS). The algorithm discovers temporal data and the similarities between users are evaluated by the proposed measure, Time Series. To our best knowledge, this is the first work on mining and identification of user behaviors based on the time series data with preferences being given for both user relations and temporal data at the same time. Improvement: Through experimental evaluation, under various settings, the performance of web usage mining is evaluated in terms of precision of users, error threshold value and number of rules extracted.


LaMgAl11O19 was synthesized at 1550 °C using La2O3, MgO and Al2O3 as raw materials. The samples were characterization by XRD and SEM. The tablet shaped crystals free of impurity phase formed under this condition. The thermal diffusivities were measured by laser flash method and the determined intrinsic thermal conductivities decreased as temperature increases from 25 °C to 1000 °C. As comparison, intrinsic thermal conductivities of LaMgAl11O19 are lower than that of 7YSZ. The synthesized LaMgAl11O19 was heat treated at higher temperature from 1600 °C to 1700 °C and no change in the phase indicates that the LaMgAl11O19 phase is stable under 1700 °C, which is very important for thermal barrier coatings (TBCs) serving at elevated temperature.


This article considers American foreign relations with Angola by exploring the application of so-called adaptive education. Beginning in 1919, black American missionaries at the Congregational Galangue mission station instituted systems of schooling originally developed among freedmen and women in the American South after the Civil War. These pedagogies were specifically designed to educate black Americans without upsetting dominant white structures. When transferred to Angola, these same teachings helped to empower Angolans economically and, ultimately, politically. And yet, they carried with them the unresolved legacy of American slavery. The success of Southern-inspired mission schools among Angolans opens up new questions about the legacies of slavery in US foreign relations with Angola and Africa.


. Tourism is one of the driving sectors of the national economy. Nowa-days, the normal opening of tourist destinations after COVID-19 pandemic, tourist visits are currently increasing rapidly. Indonesia has a unique culture, nature, language, and cuisine. This is certainly a potential that can attract tourists to visit this archipelago country. To increase the attractiveness of tourism, one of the things that can be done is to create a recommendation system. This system needs to be built to provide users with personalized recommendations based on the input that the user has given. This research uses primary data. The data is a tourist place in the island of Madura. The amount of data consists of 160 tourist places. While the rating is done by 120 users. The system built consists of steps: preprocessing, creating, and training the model based on the data split, calculating the error, and showingdestinationrecommendationstoauser.Preprocessingconverts"user"and "place"intointegerindexes.Creatingthemodelisdonebyembeddingbetween "user"and"place".Theratingisnormalizedtoanumberbetweenzeroandone usingasigmoid.Furthermore,trainingdataiscarriedoutusingModifiedNeural Network.Thetestresultsshowvalidation_RMSEforeachregency(Bangkalan, Sampang, Pamekasan, and Sumenep) is 0.3663, 0.3523, 0.3581, 0.3905. The recommendation system produces seven destinations as recommendations for places that have not been visited by the user.


Infertility, as a social and cultural problem affecting individuals and families, makes People Living with Infertility (PLWI) to seek solution through different pathways, but with little or no information on patriarchal barrier(s) militating against counselling in the course of treatment. The study, therefore, investigated infertility treatments and counselling in the context of patriarchy among Ijebu, south western Nigeria. The study utilized Ecology Model as theoretical guide and


Monoculture and intensive use of mechanization and inorganic chemicals are leading to degradation and erosion of our soils and agro-ecosystems. At the same time, the production of animal feeds that are rich in protein is constantly decreasing in many European countries. Modest cultivation needs, favorable content of nutrients, and beneficial effect on the environment, make field pea and oat mixtures promising crops to tackle these issues. In three growing seasons and without irrigation or fertilisation, we have examined two basic field pea cultivars (Kosmaj, OS Adam) and one leafless cultivar (OS Letin) intercropped with oat (NS Jadar), with seeding rates, field pea: oat – 100:10%; 100:20%. Results have shown that basic type cultivars have better overall development and higher yields compared to leafless cultivar, whether grown as single crops or in the mixture. Basic cultivars (OS Adam, Kosmaj) achieved higher protein content, compared to cultivar Letin, 163.9 g kg-1 , 153.3 g kg-1 , 136 g kg-1 , respectively. Yields were higher in 100:20% mixtures, compared to 100:10% mixtures and single grown crops, and we conclude that intercropping these species is superior to cultivating them separately. Protein content wasn't significantly different between two seeding rates, thus seed rates shouldn't be lower than 100:20%.


7558 Background: Lung cancer is the leading cause of cancer death. Response and survival of patients (pts) with stage III lung cancer in minority population is not well studied.

METHODS
79 pts treated between 2001 and 2006 were studied as a retrospective cohort. Clinical and survival data were analyzed using fisher's test, chi square test, Kaplan Meier analyses.

RESULTS
33 Pts had Stage IIIA; Median age at diagnosis was 58 yrs (37-75). 14 were males (42.4%) 19 females (57.6%) 26 African American (78.8%) and 7 Caucasians (21.2%). Median number of co morbidities 2 (0-4). Mean follow up was 25 months (mo) (2 - 93), 19 had surgery (12 Lobectomy (36.4%), 7 Pneumonectomy (21.2%)) and 14 were unresectable (42.4%). All pts received adjuvant chemotherapy. Unresectable pts received chemotherapy and radiation, 8 carboplatin and gemcitabine and 6 cisplatin and etoposide. Median time to progression in resectable IIIA was 23 mo (2- 67), unresectable IIIA was 12 mo (3-93). Median survival in pts with resection was 26 mo (2 - 67), unresectable was 12 mo (5 - 93). Overall survival and time to progression was not influenced by sex, race, tumor type. 46 pts had stage IIIB, median age at diagnosis 57.5 yrs (40-68). 31 were males (67.4%) 15 females (32.6%) 29 African Americans (63%) 11 Caucasians (23.9) 3 Asians (6.5%) and 3 Hispanics (6.5%). Median follow up was 10 mo (3-97). All pts received chemotherapy and radiation. 23 received cisplatin and etoposide (50%), 14 carboplatin and gemcitabine (30%), 5 carboplatin and etoposide (9%), 5 carboplatin and paclitaxel (9%). 13 had complete response (28.3%), 15 partial response (32.6%), 2 stable disease (4.3%) and 10 Progression (21.7%). Median time to progression was 9 mo (3-97). Median overall survival was 10 mo (3-97). Overall survival and time to progression was not influenced by sex, race, tumor type, chemotherapy regimen.

CONCLUSIONS
In this minority based cohort response, time to progression, overall survival in both IIIA and IIIB pts is much lower then historical controls. The overall survival and time to progression in both IIIA and IIIB is not influenced by race, sex, tumor type and type of chemotherapy regimen. Further investigations of disease and healthcare disparities in the underserved minority population, are warranted. No significant financial relationships to disclose.


Given a molecular valence‐bond wave function (constructed according to the approximation of perfect pairing), the general theory is presented for calculating either (1) the energy following complete nonadiabatic dissociation of the atoms (hence, the promotional energy) or (2) the intra‐atomic energy of the molecule for equilibrium positions of the nuclei. It is found that existent methods and tables are generally sufficient for treating only molecules having less than two unpaired electrons and, if hybridization is admitted, only molecules having less than two bonds. Tables are here given which serve the needs with respect to all possible structures involving s‐ and p‐valence electrons. Promotional energies for the CH and CH2 molecules are derived for illustration.


Prophylaxis with low‐dose aspirin may reduce the risk of pre‐eclampsia (PE) if introduced in first trimester. The performance of first trimester maternal serum screening for PE using free leptin index (fLI) and PAPP‐A, where fLI = leptin/leptin soluble receptor was studied.


Current policy encourages 'partnerships' - between statutory organisations and professionals; public and private sectors; with voluntary organisations and local communities. But is this collaborative discourse as distinctive as the government claims? These claims are critically examined, using evidence from a wide range of welfare partnerships.


The invention discloses a light source drive circuit, a color temperature controller and a method for controlling light source color temperature. The light source drive circuit for driving a light source with adjustable color temperature comprises an electric power converter coupled between a power supply and the light source and the color temperature controller coupled to the electric power converter, wherein the electric power converter is used for receiving electric energy from the power supply and providing the adjusted electric energy to the light source; the color temperature controller is used for receiving a switch monitoring signal for instructing the operation of a power switch coupled between the power supply and the electric power converter and adjusting the color temperature of the light source on the basis of the switch monitoring signal. The light source drive circuit has the advantages that light source color temperature adjusting is achieved by operating the power switch, extra special devices are not needed, simpleness and convenience are achieved, and cost is saved.


Contents: Introduction Seeing is believing: performing reform in Colley Cibbers' Love's Last Shift Sincerity as spectacle: Susanna Centlivre's The Gamester and George Farquhar's The Inconstant Reforming the reformer: female gaze and rake reform in Colley Cibber's The Careless Husband and The Lady's Last Stake Jokes and party strokes: Whig ideology and wife-reform in Richard Steele's The Tender Husband and Charles Johnson's The Masquerade Horns, whores, and happy marriages: reforming jealousy in Charles Johnson's The Generous Husband and Benjamin Hoadley's The Suspicious Husband Afterword Works cited Index.


Heizmannia (Heixmannia) greenii (Theobald, 1905) is one the the earliest recognized members of the genus, but it has never been adequately defined in its major life stages. This paper presents redescriptions of the male, female and larva, and a first description of the pupa of this species. The distribution of greenii and its bionomics, including man-biting behavior in Sri Lanka, are discussed.


Fluconazole is the most potent antifungal agent, after metabolic conversion to 5-fluorouracil, by the enzyme uracil phosphoribosyl transferase, is either incorporated into RNA or metabolized to 5-fluoro-2'-deoxyuridine-5'monophosphate, a potent inhibitor of thymidylate synthase, ultimately inhibition of DNA synthesis. Fluconazole is active against several Candida species, Blastomyces dermatitis, Human capsulatum, and Coccidioides species, Paracoccidioides brasiliensis, and ringworm fungi (dermatophytes). Fluconazole is also active against Aspergillus species, Scedosporium apiospermun (Pseudallescheria boydii), Fusarium, and Sporothrix schenckii, but these fungi are intermediate in susceptibility. Fluconazole penetration into cerebrospinal fluid is good and it successfully treated bacterial meningitis. Fluconazole is used either for prophylaxis and treatment of fungal infection and colonization either in infants and children. In infants, fluconazole treatment dosing-regimen consists of a loading dose (25 mg/kg) followed by a daily maintenance dose of 12 mg/kg, whose dosing intervals decrease according to postnatal age. In children, the recommended dose is of 12 mg/kg daily without loading dose. Following oral dosing, this antibiotic is well absorbed, mainly by small intestine, its bioavailability is about 100%, and it is almost completely eliminated by kidney. Half-life is lower in preterm and term infants (40 to 60 hours) compared to children (< 20 hours) because renal function is lower in infants, and it increases with infant maturation. Fluconazole has been found to be effective and safe in infants and children, however, it produces several birth-defects when administered at high doses, (400 mg daily) to pregnant women. This drug is metabolically cleared by CYP3A enzymes, and interacts with different drugs which are metabolized by CYP3A, enhancing or inhibiting their effects, pharmacokinetics or metabolism. Several Candida species may become resistant to fluconazole; the resistance-rate is flung-specie depended, and azole consumption causes fluconazole-resistance rate increasing infection-risks. The aim of this study is to review published data on fluconazole dosing, effects, distribution, prophylaxis, treatment, drug-interactions, meningitis, trials, metabolism, pharmacokinetics, and drug-resistance in infants and children. *Correspondence to: Gian Maria Pacifici, Associate Professor of Pharmacology, via Sant'Andrea 32, 56127 Pisa, Italy; E-mail: email@example.com


A method for analyzing biological data comprising expression values of a plurality of polypeptides in the blood of a subject. The method comprises calculating a distance between one segment of the curve and one axis defined in one direction, the distance being calculated at a point on the curve defined by the coordinates along the direction. The method further comprises associating the distance with the presence or likelihood of a bacterial infection of the subject. The coordinates are defined by a combination of expression values, and 90% or more of the segments are between a lower limit and an upper limit.


The article analyzes secularization as a factor of formation and evolution of the European civilization. The main stages of European history are connected with the changes in the religious sphere, with the shrinking of the sacral in favour of the secular. The article demonstrates the connection of the secularization phenomenon with the different spheres of the social and spiritual life. Today's break up with religion is the crisis of the West, when hedonism is coming to the forefront. The positive role of religion is becoming clear only now when the majority of Europeans have become non-religious.


PURPOSE: A method for carrying out rinsing operation when supplying a fiber softener in a washing machine is provided to prevent the solidification of a fiber softener by completely diluting the injected fiber softener in the final rinsing operation. CONSTITUTION: A method for carrying out rinsing operation when supplying a fiber softener in a washing machine includes the steps of supplying water for the last rinsing operation(S31), rotating a pulsator or a washing tub in a direction as necessary for diluting the fiber softener due to the lifting of water up to an upper wall surface of the washing tub or a water tub(S35), and discharging the water via a draining path after finishing the rinsing(S37).


ABSTRACT In this study, a comprehensive theoretical model of an in-position occupant restrained by seatbelt and airbag in an in-line frontal vehicle barrier impact is proposed. A novel approach is adopted in formulating the occupant motion based on occupant interaction with the seatbelt and airbag. Also, the airbag model developed in this paper simulates for airbag deflation both before and during occupant interaction. The proposed model is validated against test results by the system identification method through parameter optimisation. The optimisation problem is stated as a mixed integer non-linear programming problem to be solved by genetic algorithm. The results obtained with the proposed model are in good agreement with test results with a root mean square deceleration error of 0.13837 g. Furthermore, the computational time for the model has been estimated to be exceptional.


The microstructures and mechanical properties of the as-cast Mg-5.5Zn-1Y-0.5Zr based alloys with 0-1 wt pct stannum (Sn) micro addition were investigated. The results indicate that Sn has an obvious effect on refining microstructures, which is related to the variations of the hindering effect to grain growth and constitutional supercooling resulted from the segregated Sn atoms at advancing solid/liquid interfaces. Tensile tests indicate that the alloys exhibit excellent increasing strength but decreasing elongation with increasing Sn content, which is attributed to the improved grain bonding strength.


Dry itching skin is a concomitant of several skindiseases. It also is observed as a primary dermatologic complaint in the aged, and in persons intolerant to soap or frequent bathing. Pillsbury and associates (1) state that lack of water is the important defect contributing to dry skin, and that skin lipids may be important in preventing water loss from the stratum corneum. The studies of Berenson and Burch (2) indicate that keratin may act as a matrix in withholding lipids or lipoprotein complexes, and these complexes are probably the chief barrier to water loss. Prominent among the lipid constituents of the skin are the phospholipids. These polar, fat and water-soluble substances play a vitally important role in the physiologic activities of all living cells. It is significant that the concentration of phospholipids in both young tissue and repair tissue is considerably higher than in other types of cell (3). As the phosphatides form part of the cell membrane, the extent of their hydration may well be a determining factor of the water-carrying capacity of the whole tissue. In a recent study, Elworthy (4) measured the adsorption of water on phosphatides and found it to be of considerable magnitude. These observations on the role of the phospholipids stimulated interest in the development of a bath oil high in phospholipid content.' In contrast to most other bath oils which do not contain phosphatides but contain chiefly mineral oil, this new preparation is devoid of both mineral oil and lanolin. Thus it has a closer relationship to the normal lipid content of skin and advantageously lacks a potentially allergenic lipid of animal origin.


The present invention discloses a handle fitted onto the outer pan to the displacement direction of the operating member and the operation of the swing operation of the thumb swing direction of this body as far as possible the same, to provide a shift operation device having an excellent operational feeling of operation which is shift cable with the outer circumferential direction at a predetermined width of the handle adjacent the handle configuration is provided, which has about the pivot axis of the swing operation of swinging the operation member is provided with a handle adapted to the outer periphery of the mounting hole of the swing operation member decides swing guide member guide surface displacement path, and said pivot axis inclined to the axis of said handle.


It is shown that for the Exe Jahn–Teller problem, the circulation, the line integral along a closed loop, of the actual, or an approximation to the, derivative coupling can be used to determine the number of closely spaced conical intersections in that closed loop. This approach has advantages over the use of the geometric phase theorem, which can only count conical intersections mod 2. The circulation is used to establish the locus of the seam of the conical intersection of the 2 2E′ state of Na3. It is found that in addition to the D3h seam of the conical intersection, three symmetry equivalent seams with C2v symmetry exist in close proximity to the D3h seam. The three C2v seams intersect the D3h seam. The net geometric phase effect is largely suppressed and this ostensibly Jahn–Teller pair of electronic states is more like a Renner–Teller pair.


Through the lens of non-commutative function theory, we examine a non-selfadjoint variant of the Kadison--Singer problem on extensions of pure states. More precisely, given a unital subspace $M$ of a $C^*$-algebra $B$, we aim to characterize those pure states on $M$ admitting a unique extension to a state on $B$. We find naturally occurring examples where every pure state has this property. In the more structured setting of a subalgebra $A$ of $B$, we shed light on the uniqueness of extensions via the existence of excisions in $A$, in the sense of Akemann--Anderson--Pedersen. Certain non-commutative peak points, both in the state space and in the representation space of $B$, play a crucial role in our analysis. In particular, the question of abundance of non-commutative peak points is addressed.


The tremendous development in the past ten last years of the Internet and ICT at large (whether it be in general technologies like semantic modeling, knowledge mining, RFID or mobile technologies, or domain-oriented ones like e-commerce, collaborative spaces, digital mock-ups, etc.) has opened a large spectrum of potential applica-tions of ICT in the Construction sector. The real adaptation and deployment of ICT in Construction has indeed just started, and there is a high need to organize and plan future R&D actions for Construction ICT, while at the same time to better evaluate the benefits and thereby convince Construction actors. This is the role of the Strat-CON and BICT projects, respectively, which are introduced in this article in terms of their aims and major results.


wisely employed in reading Dean Inge's Plotinus, which will tax the grey matter of anyone. Preaching, of course, should contain both these elements, but its main function is not to indulge the sentimental or the intellectually conceited until they nod in complete satisfaction, but to make men conscious of God speaking to them directly, personally, challengingly, the truth of the New Testament. And if this be the case, then the tragedy of our day, so far as the Church is concerned, is that while many are prepared to 'accept the Church's gift of social fellowship throughout the week, and pastoral attention, it is the few who wish preaching-the instrument by which men hear God speak His word personally and challengingly to them, which is the most important thing in Christianity. 5. Is this not the summing up of that MarthaMary passage so oft distorted by people ? Of


A new ferroelectric, C NH2 3 4Br2SO4, has been characterized by dielectric, calorimetric and dilatometric methods, and its paraelectric and ferroelectric structures determined by x-ray diffraction. The crystal undergoes the first-order ferroelectric-paraelectric phase transition at TC=365.5 K. The transition is driven by disordering of the SO4 2− anions, but the spontaneous polarization originates essentially from the ionic displacements. The temperature dependence of the order parameter is well described by Landau's mean-field approximation. By comparing with C NH2 3 4Cl2SO4 crystal it has been shown that the Br/Cl halogen atom exchange caused the anisotropic deformation of the crystal lattice modifying the ionic and hydrogen-bond interactions, resulting in the upward shift of the Curie point, the essential changes in the crystal phase diagram, and modified ferroelectric properties. Although the paraelectric phases of C NH2 3 4Cl2SO4 and C NH2 3 4Br2SO4 are isostructural in tetragonal space groups I42m, below TC the first one becomes a two-directional ferroelectric in space group Cmc21, while the second one a one-directional ferroelectric in space group Fmm2. The roomtemperature ferroelectricity, and the high piezoelectric response and large electric field-switchable strain, revealed in C NH2 3 4Br2SO4, can be useful for electronic applications.


Both a product of globalization as well as a catalyst, the Internet connects computer users
around the world. Social networks are considered as a social communication in terms of
globalization. The impact of globalization processes on the integration of verbal and nonverbal
forms of social communication Two components of globalization – integration and
acceleration – will become the two projections in research of "social communication"
phenomena.


Using density functional theory (DFT) including van der Waals interactions, we examine work-function (WF) tuning of H:Si(111) over a range of 1.73 eV through the adsorption of alkyl monolayers with the general formula −[Xhead group]–(CnH2n)–[Xtail group], X = O(H), S(H), NH(2). The WF is practically converged at four carbons (eight for oxygen) for head-group functionalization. For tail-group functionalization and with both head and tail groups, there is an odd–even effect in the behavior of the WF, with peak-to-peak amplitudes of up to 1.7 eV in the oscillations. This behavior can be explained through the orientation of the terminal-group dipole. The shift in the WF is largest for NH2-linked chains and smallest for SH-linked chains, which can be rationalized in terms of interface dipoles. Our study reveals that the choice of the head and/or tail group effectively changes the impact of the alkyl chain length on the WF tuning using self-assembled monolayers. This is an important advance in utilizing hybrid ...


Human Attribute Recognition (HAR) is a highly active research field in computer vision and pattern recognition domains with various applications such as surveillance or fashion. Several approaches have been proposed to tackle the particular challenges in HAR. However, these approaches have dramatically changed over the last decade, mainly due to the improvements brought by deep learning solutions. To provide insights for future algorithm design and dataset collections, in this survey, (1) we provide an in-depth analysis of existing HAR techniques, concerning the advances proposed to address the HAR's main challenges; (2) we provide a comprehensive discussion over the publicly available datasets for the development and evaluation of novel HAR approaches; (3) we outline the applications and typical evaluation metrics used in the HAR context.


Coronary artery bypass grafting (CABG) is a common procedure performed commonly using left internal mammary artery (LIMA). We report a case of sternal wound dehiscence and breast necrosis following LIMA harvest in a 55‐year‐old obese lady with macromastia, diabetes mellitus, hypertension and end stage renal disease requiring dialysis. We also review the existing literature.


Biochar which is derived from agricultural wastes (crop residues, livestock manures, etc.) could contribute to a significant carbonemission reduction in the agricultural environment. In this study manufacturing of biochar from tomato crop residues was tried to findout an optimal manufacturing condition. It turned out that igniting at 550℃ led to a higher quality biochar in term of high surface areaper mass (BET) and C content. The manufactured biochar was successfully used to remove naphthalene in aqueous phase. This willcontribute to an eco-friendly removal of toxic volatile organic compounds including naphthalene found aqueous and gaseous phases.


[Objective] The aim was to screen out high-quality rape combinations for national test group of high-density.[Method] 6 kinds of high-quality combinations were made a broadcast test with random block experimental design.[Result] H0903 had the highest yield.Its average yield was 2 002.65 kg/hm2,which was 19.38% more than Youyan 10.Furthermore its comprehensive characters were better,so it was suitable for close-planting.The average yield of H0904 was 1 715.10 kg/hm2 which took the second place,so H0904 could participate in multi-point regional test appraisal.Compared with Youyan 10,H0901 had a reduction of output slightly,so it should be screened sequentially.Compared with Youyan 10,H0905 and H0902 had a larger reduction of output,so they should be eliminated.[Conclusion] H0903 could participate in the national test group of high-density.


Comprehensive screening for the detection of drugs and toxic compounds in biological samples is an important function of toxicological analysis. As the demand to monitor the ever increasing number of drugs continues to rise, so too does the need to detect and quantify these compounds in a simple, single and automated run; providing a fast turnaround time for the results. This presentation describes the rapid cleanup of serum samples and detection of over 100 drugs using On-line SPE LC-MS/MS screening and confirmation. The LC-MS/MS was operated in Multiple Reaction Mode (MRM) for detection. Dependent MS/MS spectra were acquired in the Enhanced Product Ion (EPI) mode after being triggered from a Scheduled MRMTM Pro Algorithm Information Dependent Acquisition (IDA) survey scan. Combining MRM and product ion spectral acquisition allows for compound identification with highest confidence based on mass spectral library matching. The automated workflow monitors large panels of analytes; detecting and quantifying these compounds in a single run.


In this study, we investigate the masses and decay constants of the light mesons with $J^P = 3^-$ ( $\rho_3, \omega_3, K_3, \phi_3$) within the QCD sum rules method by taking into account $SU(3)$ violation effects. We state that our predictions on masses of the considered mesons are in good agreement with experimental data within the precision of the model.


Introduce monitoring condition of medium and small pumps off-line with the SnapshotTM portable data collectors produced by GE company in our factory,and detail the instrument configuration,data collection,communication operation and diagnosis effects etc.


CONCLUSION AND PERSPECTIVES The cytochrome P450 (CYP450) enzymes and ABC drug transporters in the intestine and liver play a major role in the pharmacokinetics of drugs and other xenobiotics. If feed and food components also affect these enzymes or transporters, then the disposition of drugs can be altered leading to clinically relevant interactions. However, little is known about pharmacokinetic interactions between drugs and food or feed contaminants. Mycotoxins are such contaminants produced by fungi and are the number one threat regarding chronic toxicity. Moreover, our research group has shown a reduction in hepatic CYP3A activity in pigs (Goossens et al., 2013), and a down-regulation of hepatic CYP3A37, CYP1A4, CYP1A5 and MRP2 in broiler chickens after exposure to T-2 toxin (Osselaere et al., 2013). Therefore it is the aim of this project to investigate the influence of oral exposure to Fusarium mycotoxins on the pharmacokinetic behavior of drugs which are substrates for these enzymes and transporters.


This paper presents the UTD modified method of calculations of propagation losses in urban areas. This method involves using optic geometry in propagation model and formula used in UTD method for reflection and diffraction wave coefficients. The superposition method is used to calculate resultant field. The calculation algorithm is formed on basis of analyses. In our paper hypothetical calculations are presented.


The initial design of a high average efficiency depressed collector for a 140 GHz sheet beam traveling wave tube (SB-TWT) is presented in this paper. Based on the spent electron beam extracted at the output port of the slow-wave structure (SWS), a single-stage depressed collector with low back-streaming current is designed by using Particle Tracking solver implemented in CST. Initial simulation results show that the average collector efficiency is 92.64% and the average current back-streaming rate is 0.78%. It is shown that the designed collector is adequate in the design of a SB-TWT with an average high tube efficiency.


S. Kamyabi * , B. ghotbooie , M. hasanabadi 1 Department of Geography, Semnan Branch, Islamic Azad University-SemnanIran 2 Department of Geography, Semnan Branch, Islamic Azad University-SemnanIran 3 Department of Industrial Management, Semnan Branch, Islamic Azad University-SemnanIran Abstract. Several parameters have been involved in choosing a suitable landfill site. Various parameters have their own importance and limitation, but final aim should be ended to a site situation with the less environmental effects. A decision model base on AHP is represented to achieve a suitable place by using some decision methods like multi criteria technique. This model has been used in Semnan land fill site search. The research result shows that using this trend can put scientific ideas in priority for finding the best landfill site in Semnan industrial zone, also this choice can decrease the extra expenses caused by unsuitable site.


This paper introduced the status of food legume production,germplasm research, and breeding programs in Hebei province, analysed the major problems in research and production, and put forward the breeding aims and some proposals for development in the future.


We propose a scheme that excites rogue waves via electromagnetically induced transparency (EIT), which can also excite breathers and solitons. The system is a resonant Λ-type atomic ensemble. Under EIT conditions, the envelope equation of the probe field can be reduced to several different models, such as the saturable nonlinear Schrödinger equation (SNLSE), and SNLSE with the trapping potential provided by a far-detuned laser field or a magnetic field. In this scheme, rogue waves can be generated by different initial pulses, such as the Gaussian wave with (or without) the uniform background. The scheme can be used to obtain rogue waves, breathers and solitons. We show the existence regions of rogue waves, breathers, and solitons as the function of the amplitude and width of the initial pulse. The novelty of our paper is that, we not only show rogue waves in the integrable system numerically, but also present the method to generate and control rogue waves in the non-integrable system.


Aim. Evaluation of efficacy, safety and functional method of determining informativeness of bile acids in serum by gas-liquid chromatography. Material and methods. To determine the content of bile acids has been selected by gas-liquid chromatography. The effectiveness of this method is shown by the example of determination of cholic, deoxycholic, ursodeoxycholic, chenodeoxycholic acids having diagnostic value. The uniqueness of this method lies in the fact that for the first time will be shown in the chromatogram relationship qualitative and quantitative composition of bile acids in the blood with clinical manifestations of hepatobiliary tract pathology. Results. Based on the processing of chromatograms calculated relative correction factors of methyl esters of bile acids. The resultant chromatograms were evaluated by the method of internal standardization. Determined by the primary bile acids, such as cholic, chenodeoxycholic and secondary bile acids: deoxycholic and ursodeoxycholic. Their ratio in the blood serum of control subjects averaged 1:1:0,8:0,2 (0,67 mg%:0,66 mg%:0,44 mg%:0,33mg%). Gender and age did not affect the content of bile acids. The total amount of bile acids averaged (1,66±0,27) mg%. Conclusion. Determination of the main bile acids in serum by gas-liquid chromatography is sufficiently accurate, minimally invasive and informative. Represented a direct correlation between the qualitative and quantitative composition of bile acids in the serum with the development of the clinical picture, which would enable earlier diagnosis of diseases.


This article documents the results of the application of the 5´S methodology in the finance department of Hospital Guanajuato Sur. With a marked leadership in the management process of the Portability System in the State of Guanajuato; offering hospital medical care to 6 states: Nuevo Leon, State of Mexico, Mexico City, Puebla, Hidalgo and Michoacan.


This paper is concerned with the problem of observer-based fuzzy control design for discrete-time T-S fuzzy bilinear systems. Based on the piecewise quadratic Lyapunov function (PQLF), the piecewise fuzzy observer-based controllers are designed for T-S fuzzy bilinear systems. It is shown that the stability for discrete T-S fuzzy bilinear system can be established if there exists a PQLF can be constructed and the fuzzy observer-based controller can be obtained by solving a set of nonlinear minimization problem involving linear matrix inequalities(LMIs) constraints. An iterative algorithm making use of sequential linear programming matrix method (SLPMM) to derive a single-step LMI condition for fuzzy observer-based control design. Finally, an illustrative example is provided to demonstrate the effectiveness of the results proposed in this paper.


Introduction:
 Aortic atherosclerotic burden is known to be associated with an increased risk of ischemic stroke. However, longitudinal data and the risk factors about aortic plaque progression are limited.

 Hypothesis:
 We hypothesized that ambulatory blood pressure (BP) variables would play a role in progression of aortic atheroma over 2 years in patients with stroke

 Methods:
 115 patients with who underwent serial transesophageal echocardiography (TEE) over 2 years were enrolled. Aortic atheroma was graded as mild (2-3mm), moderate (3-5 mm), severe (>5mm), or complex (ulceration and/or mobile component) using TEE. Progression of aortic atheroma was defined as an increase of maximal plaque thickness by ≥1 grade. Ambulatory BP monitoring (ABPM) was performed when BP was stabilized. The association between ABPM variables and aortic atheroma progression was assessed.

 Results:
 During the median follow-up of 25.0 months, 10 (8.7%) were regressed, 13 (11.3%) were progressed, and 92 (80.0%) remained unchanged. Female had more progression of aortic atheroma (p=0.007). However, baseline LDL cholesterol, change of LDL cholesterol, intensity of statin and baseline plaque thickness were not significantly associated with change of aortic plaque. Regarding ABPM variables, systolic ABPM variables including 24 hour, daytime and nighttime mean systolic BP were associated with progression of aortic atheroma, whereas diastolic BP variables were not associated with change of aortic atherosclerosis. 24 hour, daytime and nighttime mean systolic BP were significantly related to plaque progression even after adjusting for clinical parameters (p=0.007 for 24 hour and daytime SBP, p=0.003 for nighttime SBP).

 Conclusions:
 Systolic BP variables were associated with progression of aortic atheroma in patients with stroke, which suggests systolic BP control can be a key to suppress progression of aortic plaques.


Nancy Krebs, M.D., couldn't imagine not wanting to conduct research. Even under the rigorous demands of medical school and residency, she couldn't resist the opportunity.

Rather than viewing research as an innovative way of seeking answers to puzzling medical questions Dr. Krebs, recipient of the AAP 1991 Pediatric Resident Research Award, sees it as the only way.

"All of us have questions that occur to us as we work with our patients, or we read or hear of something that makes us curious," Dr. Krebs said. "Research is the logical way of getting the answers.


To study the effect of different total solids(TS)mass fraction on biogas production of muskmelon stems and leaves,a batch of single-phase anaerobic fermentation was conducted with muskmelon stems and leaves as the test raw material at different total solids mass fraction(60,80and100g/kg)under the condition of the reactor temperature at(35±1)℃and the inoculum to substrate ratios at 30%.The result showed that the average daily production of the feed liquid at different total solids mass fraction of 60,80 and 100g/kg was 202.9,303.5,and 345.4mL/d respectively,and the cumulative biogas production increased with the increase of total solids mass fraction,with 6 087.0,10 016.5,and 12 435.5mL respectively.But the gas rate of total solids(TS),gas rate of fresh raw material and gas rate of volatile solid(VS)were both 80g/kg100g/kg60g/kg,degradation rate of total solids(TS)had the same tendency.The CH4 volumn fraction were both increased at first and remain above 50%and peaked above 64%.


Cost of quality (COQ) is usually understood as the sum of the price paid for prevention of poor quality and the cost incurred due to product and service failure. It is a significant cost driver that firms need to control effectively in order to sustain competitive advantage. Nevertheless, the
literature suggests that only very few firms in fact track and report quality cost data and use it for management control purposes. The lack of the COQ use among the companies is frequently blamed on the implementation difficulties which can easily deter the organizations from undertaking a systematic analysis of their quality costs. In spite of that, there is only
little research-based literature that addresses the practicalities of implementing COQ. Furthermore, none of the research studies so far has gone into the depth of the issue in order to investigate factors that affect the implementation of COQ in organizations.

The main objective of this thesis is thus to thoroughly examine the use, the practicalities and the obstacles in implementing the COQ programs. A worldwide-launched questionnaire was used to gather the data from the quality professionals in the companies of various sizes, industrial sectors and geographical locations. A series of focused semi-structured personal interviews with managers and persons responsible for quality in several multinational companies were carried out in order to add the depth to the investigation, to validate the questionnaire and to verify the results. Graphical representations were generated to analyze the results and to determine the positive and negative impacts of various factors on the COQ implementation. Moreover, the areas on which each specific type of company, industry and department should concentrate in order to maximize the success of the COQ implementation were highlighted. The findings of this thesis can be used by companies to help in developing quality improvement processes and in increasing their effectiveness.


Chinese journals are reporting instances of misconduct by researchers similar to those that have been troubling the American scientific community. Several articles are cited which report cases of fabrication of data, plagiarism, or unfair claims to authorship. A Chinese scientific journal has begun a regular column on ethics in science, and researchers have drafted a code of ethics for the Peking scientific community.


A flat super-continuum (SC) generated by a 1.5 µm passively fibre modelocked laser incorporating a single-walled carbon-nanotube-based saturable absorber and a normal dispersion highly nonlinear photonic crystal fibre (PCF) is demonstrated. A compressed 620 fs pulse train from the modelocked laser is obtained and launched into the PCF. Since the pulses propagate in the normal dispersion regime of the PCF, linear frequency chirp is induced by self-phase modulation which leads to a flat SC. An SC covering 200 nm with less than 7 dB power fluctuation is achieved. The experimental results are consistent with the theoretical analysis based on the nonlinear Schrodinger equation.


—Using a simple apparatus designed to perfuse nervous tissue mini‐slices retained on glass fibre filter discs, slices of adult (13 week) rat cerebral cortex and spinal cord were shown to release radioactive GABA and glycine, but not 2‐amino‐isobutyric acid, in response to increased potassium ion concentration of the perfusing medium. A major portion of this potassium‐stimulated release was dependent upon the presence of calcium ions in the perfusing medium. Slices of cerebral cortex and spinal cord from rats of 1 day and 10 days postnatal age showed potassium‐stimulated, calcium‐dependent release of radioactive GABA and glycine respectively. These findings are consistent with other evidence that GABA and glycine are functioning as inhibitory transmitters in rats at least as soon as 1 day after birth.


Aims: Dapagliflozin, a selective, orally active inhibitor of the renal sodium–glucose co‐transporter type 2 (SGLT2) is in development for the treatment of type 2 diabetes mellitus (T2DM). Here, the pharmacokinetics (PK) and pharmacodynamics (PD) of dapagliflozin were evaluated in healthy Japanese subjects and in Japanese subjects with T2DM.


Graph Search, unveiled by Facebook cofounder and CEO Mark Zuckerberg in January, is being piloted in the US before being rolled out worldwide, but it promises to connect users to people and businesses via friend recommendations and activity. However only those salons that are active and working strategically on Facebook will benefit.


Abstract : The directional shear cell (DSC) prototype was commissioned with the aims of carrying out basic research and eventually the routine testing of undisturbed samples from the field under stress paths including controlled rotation of the principal stress axes. Advances were made from previous versions of the DSC. In this prototype, testing is completely automated (including cyclic tests) with the capability to rotate the principal stress axes through 360 deg. The new version also has a significantly higher stress capacity. The aim throughout apparatus development was to produce a device which would be easy to work with. In particular, the original apparatus design required the operator to use judgement in adjusting the positions of the normal-pressure bags and the alignment of the shear sheets as the specimen deformed. It was considered very important to make these adjustments automatic and therefore objective. There are many possible research areas that can be pursued using the new DSC. An important area for practical applications is assessing the performance of various types of constitutive models for soils by imposing complex stress paths that replicate prototype loading. Areas of research for improvement of the apparatus include quality of strain measurement and automation, comparative studies of other shear apparatuses, lubrication, and specimen preparation.


The ionization behavior of anthraquinones in atmospheric-pressure chemical ionization(APCI) source was studied.The formation of intramolecular hydrogen bond of anthraquinone molecules in APCI source was firstly proposed to explain the competition action between proton transfer and charge transfer in APCI source.The ionization regular pattern of anthraquinones was studied by flow injection sampling in positive and negative ion modes in APCI source,and by HPLC sampling in negative ion mode in APCI source.Effects of ionization environment,including reaction ions type and amounts in APCI source,on ionization mode of anthraquinones were examined by changing the flow rate and mobile phase proportion.The result indicated that the proton transfer was a predominant process in positive ion mode,while a competition existed between proton transfer and charge transfer in negative ion mode in APCI source.The charge transfer was considered to be the predominant process for anthraquinones in APCI.Thus,the ionization mode in APCI source was not only affected by the structure of compounds,but also affected by the types and amounts of reactive ions in ionization environment.


The reappointed Obama administration expresses that Asia is also its focus and the orientation of its Asian policy pivots from"return"to"rebalance". However,in 2013,facing the nuclear issue of DPRK and Middle East affairs such as Iran's nuclear development and Syrian issue,Obama seemingly paid attention to the latter and he did not attend the East Asia Summit. Accordingly,its Asia-Pacific rebalance strategy is questioned. In this paper,topics including how to assess the rebalance strategy,what about the future policy of the U. S. on East Asia and how China should deal with the situation are discussed.


The system of the electronic transformer is described. Two types of optical transmission systems are compared. The optical data transmission scheme with synchronous clock imitating asynchronous transmission is presented. The data transmission through single optical fiber is realized with 16-bits serial output A/D converter and single chip computer. Demodulation of synchronous clock and converting serial to parallel transmission of data are done with CPLD at secondary side. The linearity characteristic of the electronic transformer reaches level 0.2.


The transdermal delivery of theophylline was evaluated using various ethanol (EtOH)/water (60/40)-hydroxypropylmethylcellulose (HPMC) systems with or without lauric acid as a permeation enhancer. The in vitro skin permeability of theophylline across the excised hairless mouse skin and the in vivo skin absorption of the drug using abdominal rat skin were remarkably enhanced by the addition of lauric acid to the EtOH/water (60/40) binary vehicle or EtOH/water(60/40)-HPMC systems. The limited concentration of lauric acid for the maximal permeability of the drug was 4% (w/w). The in vivo skin absorptions of theophylline from EtOH/water (60/40)-HPMC systems with 4% (w/w) lauric acid and with various concentrations of three HPMCs(65SH-400, -1500, -4000) showed essentially same patterns as that from EtOH/water (60/40) binary vehicle with 4% (w/w) lauric acid. Furthermore, EtOH/water (60/40) -3% (w/w) HPMC 65SH-4000 system with 4% (w/w) lauric acid indicated the greatest bioavailability (92.7%) in the systems investigated and was considered as the most useful recipe for delivery of theophylline applicable to the skin.


The ability of polarization modulation IR reflection absorption spectroscopy (PM–IRRAS) to study the air/water interface is presented. A brief description of the set-up and of the experimental procedure is given. Theoretical simulations accounting for the uniaxial nature of the spread monolayer lead to optimum experimental conditions (71 ° for the angle of incidence) and to a specific surface selection rule. Application to the study of cadmium arachidate, dimyristolyl phosphatidylcholine (DMPC) and polypeptidic Langmuir films illustrates the potential uses of this method.


The present invention discloses an earphone insertion detection circuit. Circuit the left sound channel (L) pin therein, with the L pin and connected and the first pin cleavable, right sound channel (R) pin and the R pins and connections and cleavable second pins, the circuit is further comprising a left detection signal line connected to said first pin, left detection signal line connected or arranged to pull-up resistor, the second pin and the first pin is electrically connected, the said L pin R pin connects the pull-down resistor, respectively. The present invention circuit is simple, small area PCB is occupied, on the cost of the hardware has a low merit can effectively improve the reliability of the earphone insertion detection. .The